Podcasts about Bolero

Oggi a Cult Estate: Cinzia Poli con gli ascoltatori e le ascoltatrici del viaggio al Dromos Festival, in Sardegna; Assia Petricelli sul libro "Le ragazze ce la fanno" (Il Castoro); la chiusura del festival Sopra di me la Grigna 2025; la regista Anna Fontaine sul film "Bolero"; Giulia Melideo sul suo romanzo "La casa al mare" (augh); le 4 serate di "8 albe. Tramonti: cosmogonie e fini dei mondi" a Noto...

Hola!! Para echar el cierre a esta 4º temporada, me he sentado a conversar con Tamara, una de las voces mas reconocidas de este pais, y que es conocida como "La Reina del Bolero. Tamara ha cosechado durante sus 25 años de carrera, que celebra este año, multitud de premios y galardones, y con ella vamos a repasar su trayectoria, y mucho mas.

Der „Boléro“ von Maurice Ravel ist der perfekte Ohrwurm – und war 1928 eine kleine musikalische Revolution. Was nicht nur mit der erotischen Uraufführung des Stücks zu tun hat.

con Stefano Chiantini regista di "Come gocce d'acqua"; dal Milano Film Fest: Anne Fontaine su "Bolero" e Ali Ahmadzadeh su "Buonanotte a Teheran - Critical Zone". Tra le uscite: "Volvereis" di Jonas Trueba; "Dragon Trainer" di Dean DeBlois; "Dancer in the Dark" di Lars Von Trier.

Wat zit er in De 7 vandaag?Doorgeefschenkingen worden pijlsnel populairder. Vorig jaar deden Vlamingen er zo een kwart meer. Da's een record. Hoe werkt het precies?De fiscus eist een recordbedrag aan fiscale kortingen terug van ondernemers. Goed voor bijna 200 miljoen euro. Hoe komt dat? En over wat voor kortingen gaat het?Beleggen op de beurs wordt hoe langer hoe toegankelijker. Na Saxo, Keytrade en Rebel verlaagt nu ook Bolero z'n tarieven voor kleinere bedragen. De slag om de jongere belegger woedt volop!En we gaan ook even naar LA. Onze man is daar ter plaatse voor het zware protest tegen het migratiebeleid van Donald Trump. Host: Bert RymenProductie: Roan Van EyckSee omnystudio.com/listener for privacy information.

Sintonía: "Tikjda" - Ahmed Malek"La ville", "La ville part 2", "Maya", "Autopsie d´un complot", "Henya" y "Bolero", extraídas de la recopilación (1xLP) "Musique originale de films" (Habibi Funk, 2016)Todas las músicas compuestas e interpretadas (al piano/flauta) por Ahmed Malek"Soul Raga", "Ghame Tanhai" y "African Jumbo", extraídas del álbum "Mehrpouya Sitar Featuring African Jumbo" (1976-Life Goes On Records/Persianna, 2009)Todas las músicas compuestas e interpretadas (al sitar/guitarra) por Abbass Mehrpouya Bonus tracks: "Halla" y "La Cote", de Ahmed Malek "Ghabile Leyli" (inédito), de MehrpouyaEscuchar audio

ESSENTIEL, UN MONDE DE LIVRES Josyane Savigneau reçoit Karol Beffa compositeur, pianiste et universitaire, pour ses livres sur Ravel et Satie « En avant la musique ! Maurice Ravel » aux éditions des Equateurs « Erik Satie de A à Z - Un musicien à la plume fantasque » aux éditions Flammarion. À propos du livre : « En avant la musique ! Maurice Ravel » paru aux éditions Equateurs Mondialement célèbre pour son emblématique Bolero, Maurice Ravel (1875-1937) était un prestidigitateur de la musique. Minutieux jusqu'à la perfection, fasciné par les contraintes, il fut le compositeur de tous les défis : la difficulté était pour lui source de beauté. Mais Ravel était aussi un esprit fantaisiste, un éternel enfant. Grand amateur de voyages, ce dandy à l'élégance raffinée alla puiser une part de son inspiration dans les musiques anciennes, espagnoles, orientales, ainsi que dans le jazz. Maître de l'harmonie, de la forme, de l'orchestration, ce fut un créateur de sortilèges, un magicien des sons. Le compositeur et pianiste Karol Beffa lève le rideau sur « l'énigme Ravel ». Dans un style vif et enlevé, il nous fait pénétrer dans le secret de son atelier, nous révèle ses étonnantes fréquentations et nous initie à son art de vivre, à ses manies de collectionneur, à son goût de la solitude et de la marche. Comme l'écrivit Léon-Paul Fargue, « Ravel fur un poète précieux et noble, un musicien du genre fine lame, un hidalgo gentil et probe, un être au coeur d'or ».     Coup de coeur des libraires ?? « C'est en qualité de musicien que Karol Beffa nous invite à percer les secrets de composition de ce magicien de la musique qu'était Maurice Ravel. Perfectionniste à l'extrême, soucieux du moindre détail, l'auteur du Boléro a révolutionné son art par une orchestration raffinée, des harmonies complexes et des textures rythmiques innovantes, créant des atmosphères riches et nuancées qui ne laissent pas de fasciner. Un vibrant hommage à un génie musical souvent perçu comme énigmatique, mais profondément humain ! » Librairie Compagnie (Paris) A la fois compositeur, pianiste, musicologue et écrivain, Karol Beffa, artiste franco-suisse, incarne une carrière artistique exceptionnelle, et témoigne d'un goût et d'une parfaite connaissance de l'histoire de la musique. À propos du livre : « Erik Satie de A à Z - Un musicien à la plume fantasque » paru aux éditions Flammarion Satie ne fut pas qu'un musicien. Il n'a cessé d'accorder une attention toute particulière à l'écriture, il a multiplié les jeux de mots, les calembours, les formules faisant mouche, qui peuplent ses partitions et les rendent reconnaissables entre toutes. Épistolier souvent drolatique, décontenançant ses correspondants par son agressivité ou ses incongruités, aphoriste à ses heures, il a laissé quantité de textes, dont le présent ouvrage offre une sélection. Au fil de sa plume incisive, les souvenirs intimes succèdent aux portraits de compositeurs ou aux caricatures. Ses opinions tranchées donnent un tableau réjouissant de la vie musicale et culturelle de son temps et dressent en creux un portrait farfelu de ce musicien bien connu. Compositeur et pianiste, Karol Beffa enseigne à l'École normale supérieure. Il a été titulaire de la chaire de Création artistique au Collège de France en 2012-2013, et a été sacré meilleur compositeur aux Victoires de la musique 2013. Il est l'auteur d'une biographie de György Ligeti (2016), de Parler, composer, jouer : Sept leçons sur la musique (2017) et, avec Cédric Villani, de Les Coulisses de la création (Champs-Flammarion 2017).

"Bolero", le dernier film de Anne Fontaine été présenté au Milano Film Festival, hors compétition. La biographie d'une des oeuvres musicales plus connues au monde et le conte du procès de création plus compliqué pour Maurice Ravel, une histoire pas connue et très intéressante. The post “Bolero”, interview avec la réalisatrice Anne Fontaine appeared first on Fred Film Radio.

Como todos los primeros martes de mes, el periodista Andrés Soto Guillén sobre temas lo cales y latinoamericanos con los antropólogos Ricardo Mariani en Ponce y Javier Hidlago Cabeza desde Chile. En esta edición, la conversación gira en torno al aumento en la represión política y social en El Salvador, la novel elección de jueces por voto popular en México. El diálogo culmina comentando el bolero que sirve de banda sonora a la película In The Summer

What are the best brokers for investors in Belgium?Which ones are the cheapest?Which ones are the safest?Which ones handle all Belgian taxes?Which ones are the easiest to use?In this episode, we analyse and compare the 12 main brokers used by investors in Belgium, so that you can pick the best one.We cover the following brokers: Bolero, Degiro, Keytrade, Saxo, Re=Bel, Mexem, MeDirect, ING Self Invest, Lynx, Trade Republic, Bux and Interactive Brokers.Over the past 13 years investing in the stock market, I've changed brokers several times. And because I have a portfolio of index funds of over 1 million euros, it's important for me to pick the best one.I have also helped thousands of investors (from very beginners to advanced) select their brokers. To do so, I've developed a comprehensive research and comparison framework, which we explain in this episode. For this 2025 version, Toon and I have spent 3 months reviewing all brokers information, emailing them and calling them to fill the gaps. It's a ton of work. Huge thanks to Toon for doing the heavy lifting for this 2025 update.The FIRE Belgium Broker Comparison Table used to be for the participants of the Index Investing Online Course only, but I'm making it available for free so that everyone can benefit from the research. I also hope this will help brokers improve their services over time.If you find this helpful, please subscribe, hit the like button and share the episode (or this email) with a friend. They'll thank you later.To get the full value of this episode, make sure to download the full FIRE Belgium Broker Comparison Table for free on the FIRE Belgium website: http://firebelgium.com/brokers What's next?Brokers are an important part of index investing. But it's only one part of the system you need to setup.You also need to understand taxes, pick the right ETFs, determine your asset allocation build your personal investment plan, and then figure out all the practical stuff.It can feel overwhelming.And to help you I invite you to watch the Free Workshop on the FIRE Belgium website: How to Build Wealth on Autopilot: Evidence-based Investing, optimized for Belgian taxes.In the workshop you will learn:How to invest to get better results than banks and professional fund managers – while doing 0.1% of the work and paying 10 times less. Proven by 50 years of academic research.How to minimize Belgian investment taxes and optimize returnsHow to invest well with 100 euros (you don't need much to get started!) in less than 5 minutes a monthHow to get started with index investing in Belgium in just a few weeks – my practical roadmap to learn everything you need to know and start investing with confidence.Watch the workshop on demand at http://firebelgium.com/investingworkshop And if you want quick responses to your questions, Toon (who is the special guest on this episode) and myself are also available for 1-on-1 consultation calls. You will find those details on http://firebelgium.com/1on1 ---Learn about Financial Independence in Belgium: https://firebelgium.com

¡¡NUEVO PODCAST!!-Primera Bailarina. Elisa Carrillo...  “Gala Elisa y Amigos  con Bolero de  Maurice Béjart”  -Roberto Jaime González… “Hot Sale 2025”-Dra. Miriam Neri Carmona… “Día Mundial contra el Melanoma”  -Martín Barba y   Xevi Aranda…  Obra: “Manual Básico de Lengua de Señas para Romper Corazones”

Ella regresa al Auditorio Nacional con una noche inolvidable de ballet: Bolero

Fergus Grady, Director of the French Film Festival Aotearoa, previews this year's programme – a star-studded affair featuring Sarah Bernhardt, Charles Aznavour, Marie Antoinette, the Count of Monte Cristo, Laure Calamy, two films about art thieves and the story behind Ravel's “Bolero”!Go to this episode on rnz.co.nz for more details

90.9 WRCJ's Haley Taylor speaks with the Detroit Symphony Orchestra's Music Director & Conductor Jader Bignamini. The Orchestra performs a 150th birthday celebration for Ravel which includes Le Tombeau de Couperin, Bolero and the Piano Concerto in G. Listen to them discuss the concert in this excerpt.

Invité par le Théâtre du Châtelet, le ballet du Grand Théâtre de Genève a présenté un triple programme avec : « Strong » de Sharon Eyal, « Bolero » de Damien Jalet, Sidi Larbi Cherkaoui et Marina Abramović et « Busk » de Aszure Barton. L'occasion pour moi d'inviter Aminata du compte @amyxus_ (sur instagram et tiktok) et d'en discuter ensemble dans un café bruyant. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Heute im Life After SAE Podcast: Till Schreiner (SAE Bochum), Testingenieur bei Riedel Communications. Till spricht über seinen Weg von der SAE Bochum über RTL zu Riedel. Er diskutiert die Bedeutung von Zertifikaten, die Herausforderungen seines Jobs und stellt das Bolero-System vor, für das sein Team und er einen Emmy Award erhalten haben. Er erläutert den Testprozess, die Entwicklung neuer Firmware und die Bedeutung von Cloud-Technologien undRemote Production für die Zukunft der Branche. Zudem diskutieren wir die Wichtigkeit von Zertifikaten, die Verantwortung als Testingenieur und geben Einblicke in den flexiblen Arbeitsalltag. Abschließend gibt Till wertvolle Tipps fürangehende Fachkräfte im Audio- und Broadcast-Bereich.https://www.linkedin.com/in/till-schreiner-324047187/Life After SAE auf Instagram: https://www.instagram.com/lifeaftersae/Mehr zu Kurt gibt's hier:https://www.instagram.com/kurt_jonathan_engert/Mehr zu Glen gibt's hier:https://glenschaele.com/linktree

Giovanni Bottesini - BoleroJoel Quarrington, double bassAndrew Burashko, pianoMore info about today's track: Naxos 8.554002Courtesy of Naxos of America Inc.SubscribeYou can subscribe to this podcast in Apple Podcasts, or by using the Daily Download podcast RSS feed.Purchase this recordingAmazon

En este episodio, recibimos a Comisario Pantera y Fabiola Roudha, quienes nos presentan su emotiva colaboración “Vuelveme a Besar”, un bolero soul con tintes de rock que revive la nostalgia romántica con un sonido fresco y elegante. Hablamos sobre el proceso creativo detrás del tema, cómo surgió la idea después de una presentación en vivo en Los Ángeles y la magia que se generó al unir dos estilos tan distintos pero complementarios. Además, exploramos el valor emocional de un beso, la evolución del bolero y lo que podemos esperar del próximo álbum de la banda. Síguelos en redes: @comisariopantera en Instagram y TikTok, y @fabiolaroudha en Instagram, Facebook y TikTok. Mi Libro: Echale a Tu Dinero en Amazon: https://amzn.to/4iNdVGm Videos Similares a este: Helen Ochoa: https://www.youtube.com/watch?v=407bZH5NBlk Luisito Comunica: https://youtu.be/paNJ6aHFc3A?si=3Lp_dRCcc3ngfMY6 Sergio Catalan Primera Parte: https://youtu.be/4P3idZm54Tk?si=fIjNgL1Ur78zUtWc Karina Manzur entrevista: https://youtu.be/hpTnVun9okY?si=Ny_D3tLkPbskHcD9 Luis Rodriguez Entrevista: https://youtu.be/aUjKUoIZyR0?si=-3tU6EABGiFE-MYf Playlist "Making Money" "Generar Dinero" https://youtube.com/playlist?list=PLJ7-6Qe9CXRUdOtxWj5vWqOqzQHIDcHt9&si=7IlpL5w-FeMLbYDY _________________________________________________________________________________________________ Descarga el Libro, "Guia De Inversion para principiantes" GRATIS https://echale.net/shop/5120108b-a0e3-45ef-b578-284b66237c65?pageViewSource=lib_view&referrer=https%3A%2F%2Fechale.net%2F&show_back_button=true _________________________________________________________________________________________________ Descarga Plan de Gastos https://shop.beacons.ai/josequinterotv/80cb7775-a5b8-4cd2-b271-cf3d62df3f75?pageViewSource=lib_view&referrer=https%3A%2F%2Fbeacons.ai%2Fjosequinterotv&show_back_button=true _________________________________________________________________________________________________ Robinhood: Regístrese en Robinhood con mi enlace y ambos elegiremos nuestro propio stock de regalo.

“Unraveling Bolero”: When a middle-aged scientist experiences unexpected success as an artist, it seems like little more than a surprising career change. But then, she becomes obsessed with interpreting a repetitive orchestral piece called “Bolero.” As her obsession deepens, her health takes a turn for the worse – and the cause has a surprising connection to her favorite piece of music.“Crossing Over”: A few days after arriving in Boston, an immigrant from Mexico starts coughing up blood and experiencing horrible stomach pain. As doctors scramble to save his life, they have to contend with their patients' reluctance to share his background. But when they finally learn the truth, it unlocks the key to everything.Be the first to know about Wondery's newest podcasts, curated recommendations, and more! Sign up now at https://wondery.fm/wonderynewsletterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jay takes us back to 1997 to revisit the album S.C.I.E.N.C.E. by Incubus. The album preceded their commercially successful 1999 album, Make Yourself. It's heavier and funkier and was the last album to include DJ Life. It is worth a listen, you should check it out.Songs:Incubus - “Summer Romance (Anti-Gravity Love Song)”Incubus - “Deep Inside”This week on News with Nick, Snoop & Dre collab on a Nashville Gin bar, and we have a selection of music related films coming out soon to discuss.Song: Tortoise - “Organesson”Finally, can we talk about Greg Loman for a second? We close the show out with a very special Review the Review. It seems as though a write for SDShowz made it to the Beck's Bolero & Red Not Chili Peppers' gig in San Diego last week and, boy oh boy, were they impressed with Greg! We read the whole darn review, we bask in Greg's awesomeness and we celebrate his modesty. If you wanna read/laugh along, you can find it here: https://sdshowz.com/f/red-not-chili-peppers-beck-bolero-at-house-of-blues-san-diegoSong: Nas - “N.Y. State of Mind”

Llegó el momento de retomar la última parte de la música en Latinoamérica. Ya escuchaste hablar de géneros emblemáticos del continente como la salsa, el merengue, la bachata, la cumbia, el reggaetón y la ranchera. Y hoy daremos finalización al tema con 3 géneros más. Los videos de las canciones de los que acá hablaremos los podrás encontrar en la transcripción del episodio, que se publicó en el blog espanolcontodo.com. 🔴 Artículo publicado en: https://www.espanolcontodo.com/2025/03/la-musica-en-america-latina-tango-bolero-pop-rock.html 🔴 Revista "Lecturas Niveladas", número 2: https://espanolcontodo.gumroad.com/l/revista-lecturas-niveladas-2 🔴 Todos los episodios gratuitos del Podcast Español Con Todo: https://www.espanolcontodo.com/p/podcast-espanol-con-todo.html 🔴 Clases de español para extranjeros (ELE) con Luddey Florez en Italki: https://www.italki.com/teacher/3089491 🔴 Clases de inglés y español para extranjeros (ELE) con César Florez: https://preply.com/es/profesor/4371710 🔴 Materiales exclusivos de cultura, história y curiosidades de Latinoamérica: https://espanolcontodo.gumroad.com/ Español Con Todo, presentado por los profesores de español como lengua extranjera (ELE), Luddey y César Florez. ✅ MÚSICA DE FONDO ✅ Real Estate Explainer Corporate - Notas de Sucesso Home and Real-Estate Corporate - Notas de Sucesso Corporate Aspirational Music (Business Presentation) - Notas de Sucesso Business For Life (Optimistic Background) - Notas de Sucesso Good Sales (Corporate, Business) - Notas de Sucesso Autumn Background (Ambient, Motivational) - Notas de Sucesso Uplifting Motivational Corporate - Notas de Sucesso Tropical Background (Summer Corporate) - Notas de Sucesso ✅ LICENCIA DE FUENTES ✅ ► Pond5 https://www.pond5.com/pt/artist/NotasDeSucesso?ref=NotasDeSucesso

Tras el disco “Juerga y vino”, del año 2021, el pianista granadino David Montañés nos sorprende con un giro en su música transitando hacía ecos inspirados en las jarchas mozárabes y en el sonido supuesto de la Iberia de las tres culturas. “Aljimía” se llama su nuevo disco recién editado, y La Tarataña la abrimos hoy con dos de sus canciones. Hay otro estreno, “Hibernarse”, el adelanto de lo que va a ser el segundo disco del dúo gallego Fillas de Cassandra. Comentamos los conciertos secretos en Toledo de Ana Alcaide, el cierre hoy mismo de la décima edición en Yepes, también en Toledo, del Festival Música Munda con Carlos Soto-Castijazz, la próxima celebración de los quince años de El Naán en su guarida de El Cerrato palentino, y las dos inminentes citas de Los Viernes de la Tradición en la villa madrileña de San Sebastián de los Reyes con Torrezneros (día 4) y Mixtura (día 11). Eclecticismo total para el último día con los relojes marcando el horario de invierno que, de todo lo dicho antes, deja constancia este repertorio: 1.- David Montañés, “Sahhára” (con J Planeta y Fandila Folk) 3:40 y “Yá fatín” 2:152.- Ana Alcaide, “Yezemi” 5:593.- Fillas de Cassandra, “Hibernarse” 2:414.- Mixtura, “Bolero de Fuente Álamo” 4:005.- Torrezneros, “Milonga para Aguedita” 3:106.- El Naán, “Afroiberia” 5:52 y “Arqueología celeste” 6:187.- Carlos Soto-Castijazz, “Lamento por Gaza” (con Isabel Martín y Diego Galaz) 5:53 y “Páxaro d’hermozura” (con Javier Ruibal) 4:33Escuchar audio

Greg's side project, Beck's Bolero, opened for the Red Not Chili Peppers to a sold out crowd at the House of Blues in San Diego this past weekend. It the group's first show and Greg shares the experience. The band features Harry Waters on the keys, Greg on guitar, Cain Daniel drums, and Zephyr Avalon on bass.Songs:Beck's Bolero - “Air Blower”Beck's Bolero - “Scatterbrain”Whenever Jay has an melange (or a stew, or a gumbo) of different topics to share, he serves up Jay's Jambalaya. Jason Isbell eschews the songwriter approach on his new solo acoustic album, King Gizzard has an unreleased documentary called Chunky Shrapnel, and the greatest two-hit wonders as written by Chris Dalla Riva (https://www.cantgetmuchhigher.com/p/the-greatest-two-hit-wonders).Songs:Jason Isbell - “Gravelweed”King Gizzard & The Lizard Wizard - “The River”We close with Three for Thursday. Nick brings new indie/alternative tracks released in the past month from Moreish Idols, Sharp Pins, and YHWH Nailgun.Songs:Moreish Idols - “All In The Game”Sharp Pins - “With A Girl Like Mine”YHWH Nailgun - “Tear Pusher”

Negotiating With Isabella.Based on a post by Ostrich Mack. Listen to the ► Podcast at Steamy Stories.Sex sells: Isabella's New Skills.Isabella Cobelli admired her reflection in the mirror. As you could guess from the name, Isabella had Italian roots.Her father emigrated from Italy in the eighties and met and married Isabella's English mother.Isabella was an only child and after her father passed away suddenly when she was 14, she became very close to her mum.Now 23 years old and graduated with an honors degree in marketing, she had matured into a beautiful young woman. Isabella had Raven-black straight hair which hung all the way down to the small of her back. She often wore it in a French plait which meant her pretty face was plain to see.Isabella had light olive skin and funnily enough an sprinkling of freckles across her nose. Her hazel colored eyes were almond shaped and her eyebrows were thicker than was considered classical beauty. Her lips looked eminently kissable.Today Isabella had chosen a slightly daring red lipstick to emphasize the shape of her pretty mouth.Her outfit was business-like and sexy at the same time. Thigh high stockings under a grey pencil skirt, topped by a matching Bolero jacket over a semi sheer impeccable white blouse. Isabella liked to dress in pretty underwear and had chosen a half-cup lace bra and matching thong. To complete the look, she had chosen two inch heels in black to give her a little more height than her 1 meter 65.So, why all this bother to get all dressed up? After graduating Isabella tried to break into a marketing job. As the economy was in a major dip, jobs in marketing were few and far between. In fact marketing experts were all looking over their shoulders, hoping not to get their exit cards.Isabella got a job eventually in sales. Not her strongest point and she hated when people assumed that sales and marketing were one and the same. ECO-Hygiene was an up and coming supplier of Eco-friendly products for industrial use.After two months there Isabella's sales figures were under target, and she was concerned that she might just get her marching orders if she didn't at least hit her goals. As a newcomer she was assigned an area in which her predecessor had failed to drum up enough business. This geographically difficult area lay half in the urban sprawl of London and half in the leafy suburbs of Sussex. Isabella was struggling and desperate to get some decent sales under her belt. Thus, what a relief it was when, two weeks ago, all of the sales reps were invited for a weekend sales seminar in one London's prestigious hotels. All of this on their free time of course.After checking in on Friday evening, Isabella decided to have one glass of wine at the bar to see if there was any male talent attending the seminar. For some reason, despite her beauty, she didn't seem to be able to hold down a relationship for long. Men of her own age bored her. They were mostly full of themselves and only wanted to talk about their amazing feats. Isabella had missed a father for her formative years and found herself graduating towards more mature men. Problem there was that most of them were married, or un-marriable, or just plain creepy.As she sat at the bar observing the melee of sales reps loudly proclaiming their victories, Isabella was shocked when a woman sat next to her and offered her a drink."Kate", the woman said."Excuse me?" replied Isabella."Kate Connors. Senior sales director for South East" came the reply."Oh, nice to meet you." Said Isabella. "Isabella Cobrelli, My friends call me Izzy" she replied offering her hand to Kate who shook it firmly."So what do you think? Any talent in here tonight?" asked Kate.Isabella blushed."Aw come on", said Kate. "I know the drill. Been here many times and had my share of dalliances""Well" said Isabella "Up until now, not much interesting to see here. Just lot of guys full of themselves holding a pissing contest."Kate laughed out loud. "I like it" she said. "You call it as it is young lady.""What in god's name brings a beautiful woman like you to a sales conference for Industrial Hygiene products?""Well, it wasn't my first choice, and it may not be sexy, but it pays the rent." Answered Isabella."It should damn well do more than just pay the rent." Answered Kate. "What are your sales figures like?" she asked.Isabella blushed once more. "It's a struggle." She answered. "I haven't been able to score any big accounts yet and I am worried I might not hit the target.""Well maybe I can help you." Replied Kate. "After all I didn't get my position by not meeting my sales targets.""Tell me your tactics." Kate asked."Well, I like to dress in a business attire so that I look serious about the product. I make sure I know all of the specs of the particular products that I want to sell on the day, so I am well prepared for the pitch. But somehow it just seems to fall flat when I am there.""What is business attire?" Kate asked."Trouser suit with a nice blouse. Low heels for practicality." Isabella replied."Humph," snorted Kate. "No wonder that the presentations fall flat. You need to make it personal. Sure, you should be all business, but you need to be sexy too. Let me guess, most of the clients are 45 plus males bored out of their minds. You need to give their day a boost. Bring something that gets their attention, and not just the product. Don't forget there are a so many industrial hygiene products on the market, and they all do the same thing. You need to make the men want to see YOU again."Isabella listened carefully to this charismatic woman, totally in awe of her self-confidence. She quietly wished she could be like her.Kate continued. "I have done all sorts to get my sales figures up, including entertaining the clients in the broadest possible sense. These men have a boring married vanilla life. They crave excitement and attention. While their wives are away at the Rotary Club organizing charity things, the men are sitting home bored out of their skulls. Work is the same thing day after day until YOU show up. Not in a pantsuit and a blouse laced up to the neck, but in something which gives their fantasy food for thought. The women too. I have also put myself out there and entertained women."Isabella was shocked and blushed intensely. Kate was basically saying she should whore herself out to get the sale."Women too?" she asked shyly."Don't knock it till you've tried it." Replied Kate. "I have had amazing encounters with women too. And though I am not gay, I do enjoy a dally with the softer sex. Haven't you ever experimented in college?"Isabella felt like she was turning purple. "No. Never." She replied."Well play your cards right and tonight might be the first night." Kate replied.Isabella was shocked and turned on at the same time.What if she could seduce her regional sales manager? She thought. That might go some way to keeping her job.Kate signaled the bartender. "A bottle of champagne." She ordered. The bartender nodded and made a gesture toward a booth on the other side of the bar.Kate wasted no time and took Isabella's hand in hers, dragging her across the bar.The sat next to each other, watching the show.Kate turned to Isabella. "Drink up. The show has just begun. Just watch how stupid it gets."Isabella took a sip of her glass and sat back to observe. "Idiots," she thought. "Tomorrow they will be too hungover to follow the seminar."The buzz from the champagne made Isabella relax and she began to fire more questions at Kate."What did you do with all those male clients then?" she asked."Everything." Replied Kate. "From flirting to blow jobs, from blow jobs to sex, to threesomes, to gang bangs. Just as long as I got my sales. My commissions were huge, I bought my house and car for cash with everything I earned. Men are stupid. They think with their dick, and once that is engaged then they will sign anything.""And the women then?" asked Isabella."Ah that is a different story." Kate replied. "That needs a lot more subtlety.""I can show you if you want." Kate offered.Isabella though about it for some minutes, whilst watching the meat market in front of them."Okay." She said. "Show me."Kate turned to her in shock. "Really?" She asked."Yes really." Isabella replied. "I have nothing to lose and everything to gain from your experience. And besides, for some reason the thought of it makes me horny.""Right." Said Kate. "Let's take this upstairs."Kate took Isabella by the hand and lead her to the lifts. They stepped in together and Kate pushed the button for the top floor. As soon as the lift doors closed, she took Isabella in her arms and kissed her gently on the lips. Isabella swooned from the alcohol and the excitement of this new adventure. It didn't take long before she responded to Kate, kissing her passionately back, her tongue exploring Kate's mouth.Kate moaned with pleasure. "Umm; Hmm. You're good at this. Sure you haven't tried this before?"Isabella grinned and said. "Definitely not. Good catholic upbringing don't you know."They arrived at Kate's floor and exited the lift. Kate's suite was just a few meters away, and when they got there Kate fumbled to get the key to work. Isabella took the key from her gently and held it against the lock. She was amazingly calm, determined to enjoy the ride wherever that might take her.Laughing, both Kate and Isabella fell through the door into the suite. Isabella couldn't help but be impressed. "So, this is what a Senior regional manager gets," she thought. "Not bad at all."There was a bottle of champagne on ice on the hall table and Kate proceeded to open it.She poured two glasses and passed one to Isabella. "Cheers Izzy." She said, raising her glass."Cheers." Isabella replied.Kate took a draught and put her glass on the table. She took Isabella in her arms and kissed her passionately on the lips. Isabella responded with her tongue and soon they were locked in a passionate embrace.Kate opened the buttons on Isabella's blouse one by one until it was completely open.She pushed the blouse back over Isabella's shoulders leaving er bra exposed. Kate bent forward and kissed Isabella's tits through the bra. Isabella held her breath, not knowing how she would react.She was surprised that it really turned her on to have all this attention to her tits. She felt her panties getting moist.Isabella decided to take some initiative herself, and opened the buttons on Kate's blouse. Kate groaned in anticipation. Isabella rubbed her thumb over Kate's right nipple and then over the left. Kate groaned even harder. Isabella moved her finger under the fabric of Kate's bra and pinched gently with her thumb and forefinger on Kate's nipples.Kate moved her arms around Isabella's back and unclasped her bra, freeing her 32c tits. Isabella's nipples were hard as bullets. Kate couldn't resist and lowered her mouth on first one and then the other nipple.Isabella felt a shockwave go through her whole body. Her juices were now flowing freely and she felt her panties get dripping wet. Not to be outdone she released Kate's 36 c tits from their restraint and copied Kate's sucking and licking.Kate almost crumpled at the knees. For a first timer Isabella sure learned quickly."Wait." She said. "Let's take this to the bed.""Yes please." said Isabella.They half stumbled to the bed, taking their skirts off in the process.Isabella stood before Kate with only her panties and her thigh high stocking still left on. Her cunt was on fire and leaking like a fire hydrant. Her juices were running down her thighs.Kate took a moment to admire this beautiful woman in front of her before slowly rolling her panties down her thighs, over the stockings and down to the floor.Isabella stepped out of her panties. She lay down on the bed, her hand demurely over her cunt.Kate knelt down at the side of the bed and removed Isabella's hand from her cunt. Kate sat admiring the neatly trimmed cunt in front of her, all the while sniffing the scent of Isabella's sex.Isabella was panting with desire. Her cunt on fire, her juices flowing freely and her nipples hard and sore. The anticipation of what was about to happen was excruciating.And then. Kate leaned forward and drew her tongue slowly from the bottom of Isabella's lips. Slowly licking and penetrating Isabella's sex.Isabella held her breath. Her heart was beating at 200 beats per minute, or so she thought.Kate was gentle. Each time drawing her tongue from under to above. Gently she penetrated Isabella with first one, and the two fingers. Isabella gasped.Kate moved once more upwards, and this time stopped at Isabella's clit. She gently licked at Isabella's love bud taking it gently between her lips and massaging it with her tongue.Inside Isabella something exploded. Her brain seemed to short circuit and her legs began to tremble uncontrollably. Her hands grabbed the back of Kate's head and pushed her harder into her cunt. Her orgasm was coming and there was nothing going to stop it.A tsunami of electric shocks shot through Isabella's body. There was no more control. Her muscles and nerves exploded in ecstasy and her juices simply spurted out of her cunt. Isabella screamed her orgasm out as hard as she could. It was an animalistic sound which she had never heard before.

Noventa y dos dias y 18 horas para florecer, resucitar, renacer. Primavera en un universal lenguaje, el de la flores. Orquídeas, rosas, violetas, claveles, nardos que se hacen canción en ”La Violetera",´“Clavelitos” o "” entre las mas conocidas, “Laberintos y espejos" o “Corazón de Bolero”, entre las que te sorprenderán. La estación de los dias que se alargan, la del amor que rima con flor. Sus luminosas canciones, sus olvidadas maneras, su lenguaje sin trampa ni cartón. . Puedes hacerte socio del Club Babel y apoyar este podcast: mundobabel.com/club Si te gusta Mundo Babel puedes colaborar a que llegue a más oyentes compartiendo en tus redes sociales y dejar una valoración de 5 estrellas en Apple Podcast o un comentario en Ivoox. Para anunciarte en este podcast, ponte en contacto con: mundobabelpodcast@gmail.com.

At the top we have confirmation of a new album by Mars Volta, and speculation of something new from Radiohead. Then, Tempo Music Investments recently acquired a quarter interest in Bruno Mars 2012 song “When I Was Your Man.” The company is now suing Miley Cyrus, claiming exploitation of their copyright for her Grammy winning 2023 hit song “Flowers.” Cyrus claims she wrote it for her ex-husband, Liam Hemsworth, who reportedly dedicated the song to her in the past. Cyrus' lyrics seem to respond to the chorus of the Mar song. Does that entitle the new copyright holder to a cut? Apparently that's for a hurry to decide.Song: KEG - “Strangers”Greg shares some Sound Advice from Chick Corea. The legendary & influential jazz pianist and composer laid down some serious wisdom about playing and improvising with other musicians. Greg found and is sharing these nuggets for everyone to reflect on. Also, Beck's Bolero will be opening for the Red Not Chili Peppers at the House of Blues in San Diego Friday, March 21. Check it out if you're in the area.Songs: Miroslav Vitouš - “Freedom Jazz Dance”Chick Core - “Humpty Dumpty”This past Sunday, a 70 year drought ended when Newcastle United beat Liverpool in the EFL Cup Final. Jay has been a fan since childhood and he's celebrating the win with an album review from Newcastle native Sam Fender. We listened to the title track from “People Watching” a few episodes back, but the full album is now out and Jay feels like it's something worth checking out. Songs:Sam Fender - “Little Bit Closer”Sam Fender - “Rein Me In”Sam Fender - “TV Dinner”

Noctámbulo, húmedo, febril, nostálgico y sutil, el bolero.Brilló de los 30 hasta bien pasados los sesenta en nombres como Los Panchos o Lucho Gatica, Agustin Lara o Consuelo Velázquez. Estrellas como Gloria Estefan no hace tanto pero entre todas, la más fugaz, poderosa y singular, “Freddy”.Una voz de contralto como un contrabajo perezoso que superaba los 150 kilos pero un 31 de Julio de 1961 le falló el corazón. Un solo disco, un relato de Cabrera Infante (“Ella Cantaba Boleros”) y la memoria de los que allí estuvieron. Meme Solis, invitado especial hoy, la conoció además de acompañar al piano a Olga Guillot o Elena Burke, ver nacer el “filin” y morir a una escena habanera de cabarets de leyenda a manos de un régimen. De todo ello en esta edición. No apta para "distantes emocionales”. Puedes hacerte socio del Club Babel y apoyar este podcast: mundobabel.com/club Si te gusta Mundo Babel puedes colaborar a que llegue a más oyentes compartiendo en tus redes sociales y dejar una valoración de 5 estrellas en Apple Podcast o un comentario en Ivoox. Para anunciarte en este podcast, ponte en contacto con: mundobabelpodcast@gmail.com.

El autor del legendario “Bolero” es objeto de una serie de homenajes en el marco de 150 aniversario de su nacimiento. Carrusel de las Artes evoca su obra con el compositor franco-español Ramón Lazkano, autor de una ópera sobre los últimos años de Maurice Ravel.

Despite a raft of laws and programmes in France to address the gender pay gap, women still earn less than men. Organic farmers try to adapt to a drop in demand for organic food. And the story of Ravel's Boléro – the world's most performed piece of classical music. There are some explanations for France's 22 percent gender pay gap – women work fewer hours on average and in lower-paid jobs. But even doing the same job and putting in the same hours, women still earn 4 percent less than men, and a barrage of legal measures hasn't managed to change that. We look at what's going on with economist Anne Eydoux and lawyer Insaff El Hassani – founder of a company helping women negotiate salaries. El Hassani highlights negative images around wealthy women and how France's "female wage", dropped in 1946, still impacts the way some employers view women's salaries. (Listen @0')France has downsized its ambitions to increase the amount of organic agriculture after a drop in consumer demand for organic food . After years of growth, especially during the Covid pandemic, inflation and a distrust in labelling have turned consumers away from buying organic produce, even as new farmers are drawn to the prospect of working in a different way. At the recent annual agricultural fair in Paris, farmers and others working in the organic sector talk about how they are adapting to the new economic reality, and the need to raise awareness of the value of organic food, beyond the price tag. (Listen @17')France is marking the 150th anniversary of the birth of composer Maurice Ravel, whose most famous piece, Boléro, is considered an avant-garde musical expression of  the machine age. (Listen @9'50'')Episode mixed by Cecile Pompeani. Spotlight on France is a podcast from Radio France International. Find us on rfienglish.com, Apple podcasts (link here), Spotify (link here) or your favourite podcast app (pod.link/1573769878).

This podcast is also recorded in Naarm, Victoria, with fellow critic Nadine Whitney reviewing two of the films screening at the 2025 Alliance Française French Film Festival.In the following reviews, Nadine discusses Anne Fontaine's Bolero and Éric Besnard's Miss Violet.For all the festival details and to purchase tickets, visit AFFrenchFilmFestival.org.If you want to find out more about the work we do on The Curb, then head over to TheCurb.com.au. We are a completely independent and ad free website that lives on the support of listeners and readers just like you. If you can and have the means to support us, please visit Patreon.com/thecurbau to support our work from as little as $1 a month. Hosted on Acast. See acast.com/privacy for more information.

This podcast is also recorded in Naarm, Victoria, with fellow critic Nadine Whitney reviewing two of the films screening at the 2025 Alliance Française French Film Festival.In the following reviews, Nadine discusses Anne Fontaine's Bolero and Éric Besnard's Miss Violet.For all the festival details and to purchase tickets, visit AFFrenchFilmFestival.org.If you want to find out more about the work we do on The Curb, then head over to TheCurb.com.au. We are a completely independent and ad free website that lives on the support of listeners and readers just like you. If you can and have the means to support us, please visit Patreon.com/thecurbau to support our work from as little as $1 a month. Hosted on Acast. See acast.com/privacy for more information.

Maurice Ravel war zwar Franzose, aber er hatte baskische Wurzeln und beschäftigte sich in vielen Werken mit Spanien. Ganz besonders in der spanischen Rhapsodie, seinem ersten großen Orchesterwerk von 1907, Die Suite verzaubert durch folkloristisches Kolorit, sinnliche Süße und einen Orchesterklang, der süchtig macht. Von Michael Lohse.

Einen „Schweizer Uhrmacher“ hat Kollege Igor Strawinsky den Franzosen Maurice Ravel genannt, der als Sohn eines Erfinders und Konstrukteurs tatsächlich mit äußerster Präzision an seinen Werken gearbeitet hat. Seine Fantasie schweifte freilich in exotische Regionen aus 1001 Nacht, in Visionen antiker Mythen, vor allem aber in die Heimat seiner geliebten Mutter, die Baskin war und deren Gesänge er tausendfältig verwandelt hat – bis hin zum berühmtesten seiner Werke, dem „Bolero“, der freilich nach seiner eigenen Aussage „keine Musik enthält“. Was war Musik für diesen rätselhaften Mann? Im Musiksalon versuchen wir dem auf die Spur zu kommen.

Albrecht, Jörg www.deutschlandfunk.de, Corso

El sábado de la semana pasada, 15 de febrero, grabamos en riguroso directo un programa con algunos de los participantes en la quinta edición del Folk Fest Región de Murcia. Dijimos ayer al acabar La Tarataña con la entrevista a Los Hermanos Cubero que hoy lo emitiríamos, y así lo hacemos. Tanto las charlas con cada uno de los participantes como sus respectivas intervenciones musicales se grabaron de corrido y sin interrupciones. Y tal cual lo emitimos, sin trampa ni cartón ni post producción.Así que con los inconvenientes del directo, he aquí todo el programa que grabamos de tirón el sábado 15 en Murcia:1.- El Pantorrillas, “Amores sin nombre” (con Juan José Robles)Charla con El PantorrillasCharla con Carlos Núñez2.- Carlos Núñez, “For Paddy”Intro con Ismael Clemente3.- Ismael Clemente, “Mayo de Valdetorres del Jarama”Charla con Ismael ClementeIntro con Juan José Robles y Carolina Palencia (Mixtura)4.- Mixtura, “Bolero de Fuente Alamo”Charla con Juan José RoblesEntrevista con Alicia Baltasar (Directora Artística del Folk Fest Región de Murcia)Intro con Carmen María Martínez Salazar5.- Carmen María Martínez Salazar, “Los santos fueron testigos”Charla con Carmen María Martínez SalazarEntrevista con Zimi Matilla (Castora Herz – Samain Music)Intro y charla con Jaime Lafuente (Presentador de todos los conciertos del Festival)6.- Jaime Lafuente-Torrezneros, “A la rueda de los alimentos” (con Juan José Robles, Ismael Clemente y Carmen María Martínez Salazar)Charla con Manuel Luna7.- Manuel Luna, “Vengo de moler/La zarza ardía”Entrevista a Esperanza Lamet (Celtic Seas)8.- Celtic Seas, “P stands for Paddy”Escuchar audio

Sich ein zweites Arschloch freuen, gilt ja als Ausdruck ausgeprägter Amüsiertheit. Hier also die Chance auf drei Arschlöcher, Flimmerfreunde, maximales Entertainment. Ist das irgendwie falsch rüber gekommen? Kommt jedenfalls gut alles mit Marvels neuem, aber auch alten CAPTAIN AMERICA: BRAVE NEW WORLD? Mit dem Gähnen wieder aufgehört dann bei AMERICAN PRIMEVAL, Style ja, Substanz, naja. Mehr Spass mit Gewalt in der heiter hitzigen Stephen King Verfilmung, THE MONKEY. Hexen, Horror, Österreich, dann bei WELCOME HOME BABY und gequältes Genie wohin man schaut, ohne notwendig schauen zu mögen, das also in BOLERO. Direkt vorweg nochmal THE DIPLOMAT nachgepudert. ANORA auch. Ahoi.

We would love to hear from you, wherever you are!https://www.perfectpitchpod.com/contact/@NickHelyHutchThank you for listening - please do get in touch with any comments!

RAVEL: Bolero, Ballet para orquesta (15.32). Orq. de la Asoc. de Conciertos Lamoreux. Dir.: M. Ravel. Gaspard de la nuit (21.46). V. Perlemutter (p.). Quel galant m’est comparable (0.58). Tou gai (0.48). E. Ameling (sop.), R. Jansen (p.).Escuchar audio

Maurice Ravel - BoleroRoyal Philharmonic Orchestra Adrian Leaper, conductorMore info about today's track: Naxos 8.554044Courtesy of Naxos of America Inc.SubscribeYou can subscribe to this podcast in Apple Podcasts, or by using the Daily Download podcast RSS feed.Purchase this recordingAmazon

Jackie Ryan is an extraordinary jazz singer who the JazzTimes Magazine has called “one of the outstanding jazz vocalists of her generation”. She sings in different languages, styles and genres including Blues, Bebop, Bossa Nova, Samba and Bolero. She's played with Clark Terry, John Mayer, Cyrus Chestnut and many others. She's performed at Ronnie Scott's in London, Jazz At Lincoln Center and the Telluride Jazz Festival.My featured song is “The Gift”, my recent single which took my ballad and, through the genius of Michael Abene, was transformed into a Big Band Samba. Spotify link.---------------------------------------------The Follow Your Dream Podcast:Top 1% of all podcasts with Listeners in 200 countries!For more information and other episodes of the podcast click here. To subscribe to the podcast click here .To subscribe to our weekly Follow Your Dream Podcast email click here.To Rate and Review the podcast click here.“Dream With Robert”. Click here.—----------------------------------------Connect with Jackie at:www.jackieryanmusic.com—---------------------------------------ROBERT'S SINGLES:“SOSTICE” is Robert's newest single, with a rockin' Old School vibe. Called “Stunning!”, “A Gem!”, “Magnificent!” and “5 Stars!”.Click HERE for all links.—---------------------------------“THE GIFT” is Robert's ballad arranged by Grammy winning arranger Michael Abene and turned into a horn-driven Samba. Praised by David Amram, John Helliwell, Joe La Barbera, Tony Carey, Fay Claassen, Antonio Farao, Danny Gottlieb and Leslie Mandoki.Click HERE for all links.—-------------------------------------“LOU'S BLUES”. Robert's Jazz Fusion “Tone Poem”. Called “Fantastic! Great playing and production!” (Mark Egan - Pat Metheny Group/Elements) and “Digging it!” (Peter Erskine - Weather Report)!Click HERE for all links.—----------------------------------------“THE RICH ONES”. Robert's sublime, atmospheric Jazz Fusion tune. Featuring guest artist Randy Brecker (Blood Sweat & Tears) on flugelhorn. Click HERE for all links.—---------------------------------------Audio production:Jimmy RavenscroftKymera Films Connect with the Follow Your Dream Podcast:Website - www.followyourdreampodcast.comEmail Robert - robert@followyourdreampodcast.com Follow Robert's band, Project Grand Slam, and his music:Website - www.projectgrandslam.comYouTubeSpotify MusicApple MusicEmail - pgs@projectgrandslam.com

In this JCO Article Insights episode, Giselle de Souza Carvalho provides a summary on  "Navigating Treatment Pathways in Metastatic Hormone Receptor–Positive, HER2-Negative Breast Cancer: Optimizing Second-Line Endocrine and Targeted Therapies" by Bhardwarj, et al and "US Food and Drug Administration Approval Summary: Capivasertib With Fulvestrant for Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Locally Advanced or Metastatic Breast Cancer With PIK3CA/AKT1/PTEN Alterations" by Dilawari et al published in the Journal of Clinical Oncology.  TRANSCRIPT Giselle Carvalho: Hello and welcome to JCO Article Insights episode for the December issue of the Journal of Clinical Oncology. I'm your host Giselle Carvalho, Medical Oncologist in Brazil focusing on breast cancer and melanoma skin cancers and one of the ASCO Editorial Fellows at JCO this year. Today, I will be discussing two articles. The first one is “Navigating Treatment Pathways in Metastatic Hormone Receptor–Positive, HER2-Negative Breast Cancer: Optimizing Second-Line Endocrine and Targeted Therapies,” and the second one is the “US FDA Approval Summary on Capivasertib with Fulvestrant  for HR-positive HER2-negative Locally Advanced or Metastatic Breast Cancer with PIK3CA/AKT1/PTEN Alteration.”  As we know, 65% to 70% of all breast cancers are HR-positive HER2-negative and this is also the most common subtype of metastatic breast cancer. The current standard of care for frontline therapy of patients with luminal metastatic disease is a CDK4/6 inhibitor in combination with endocrine therapy. However, as new endocrine and targeted therapies gain approval, choosing the best systemic therapy upon disease progression after frontline therapy is a topic of ongoing debate. Nearly 40 to 50% of HR-positive breast cancers have actionable genomic alterations and molecular testing should be a routine recommendation for patients with metastatic HR-positive HER2-negative disease. This can be performed repeating tissue biopsy at the time of progression or from archival tissue. Treatment options after progression on CDK4/6 inhibitors include alpelisib in combination with fulvestrant in patients with PIK3CA mutant tumors as seen in the SOLAR-1 trial, or capivasertib with fulvestrant in patients with a tumor mutation in (PI3K)–AKT–PTEN pathway as seen in the CAPItello-291 study, which will be discussed further.  In approximately 30% of patients, progression on frontline endocrine plus CDK4/6 inhibitor treatment is caused by endocrine resistance, frequently involving activating mutations in ESR1. For those tumors, elacestrant, an oral SERD is an option as demonstrated in the EMERALD trial. For patients with a BRCA mutation, PARP inhibitors represent another option. If no mutations are detected, everolimus, an mTOR inhibitor, can be used based on the BOLERO-2 results. The phase 2 MAINTAIN and PACE trials, along with the phase 3 postMONARCH trial support changing the endocrine therapy backbone with or without switching the CDK4/6 inhibitor. In less resourced areas, fulvestrant monotherapy is still an option to delay cytotoxic chemotherapy, though its efficacy is limited when used as a single agent. Finally, after progression on at least one line of chemotherapy, antibody drug conjugates including sacituzumab govitecan or trastuzumab deruxtecan may be an option.  Now focusing on the PI3K AKT PTEN signaling pathway, activating mutations in PIK3CA and AKT1 and inactivating alterations in PTEN occur in approximately half of luminal breast cancers. In June 2023, the CAPItello-291 trial was published and treatment with fulvestrant plus capivasertib, a PTEN AKT inhibitor, demonstrated a 3.6 month PFS benefit compared to fulvestrant alone, regardless of the presence of AKT pathway alterations. However, for those with tumors without AKT pathway alteration, an exploratory analysis showed that although there was a numerical improvement in PFS, it did not meet statistical significance, indicating that the biomarker positive population primarily drove the positive results noted in the overall population. Therefore, capivasertib plus fulvestrant was approved by the US FDA in November 2023 exclusively for patients with PI3K/AKT1/PTEN tumor alterations after progression on an aromatized inhibitor with or without a CDK4/6 inhibitor. The approved schedule of capivasertib is slightly different from that of other agents used in breast cancer. It is 400 milligrams taken orally twice a day for four days per week every week in a 28-day cycle in combination with fulvestrant. Diarrhea, rash and hyperglycemia were the most commonly reported grade three or four adverse events in the interventional group. I would like to highlight that even though the CAPItello trial excluded patients with glycosylated hemoglobin levels higher than 8% or those diagnosed with diabetes who required insulin, hyperglycemia occurred in 19% of biomarker positive patients treated with capivasertib, with nearly 2% of this population experiencing grade 3 or 4 hyperglycemia and some patients experiencing life threatening outcomes such as diabetic ketoacidosis.  By way of comparison, hyperglycemia of any grade was three times higher with alpelisib therapy in the SOLAR-1 trial, occurring in 64% of the patients and grade three or higher hyperglycemia was seen in 37% of the patients. Diarrhea was the most common treatment related adverse event experienced by 77% of the biomarker positive population. Prompt use of the antidiarrheal drugs when needed, such as loperamide must be encouraged as untreated diarrhea can lead to dehydration and renal injury. Cutaneous rash occurred in 56% of the biomarker positive population in the interventional group and 15% experienced a grade 3 or 4 rash. Nearly half of the patients with cutaneous adverse reactions required treatment and this was the leading reason for dose reduction of capivasertib.  In the biomarker positive population, the improvement in medium PFS were 4.3 months by investigator assessment. Overall survival data from the CAPItello-291 trial is still immature, but quality of life data was recently published in September this year and was assessed by the 30 item QLQ C30 questionnaire and the QLQ BR23, the breast module. According to Oliveira et al, global health status and quality of life were maintained for a longer period with capivasertib fulvestrant than with placebo fulvestrant except for symptoms of diarrhea which were significantly worse in the capivasertib group. The median time of deterioration of global health status and quality of life was twice as long in the capivasertib group being almost 25 months versus 12 months in the placebo fulvestrant group. These data reinforced the use of capivasertib in combination with fulvestrant for the treatment of HR-positive HER2-negative advanced breast cancer patients with PIK3CA/AKT1/PTEN tumor alterations who have progressed after an aromatase inhibitor-based therapy with or without a CDK4/6 inhibitor.  Thank you for listening to JCO Article Insights. This is Giselle Carvalho. Don't forget to give us a rating or review and be sure to subscribe so you never miss an episode. You can find all ASCO shows at asco.org/podcasts. See you next time.   The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.  Guests on this podcast express their own opinions, experience and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement.  

Increíblemente, un hombre pequeño, delgado, con imagen totalmente alejada de lo farandulesco, se convirtió, desde 1953, en uno de los cantantes más populares de Cuba. Otra de las valiosísimas entrevistas de Don Galaor, en la revista Bohemia, nos presenta a Orlando Vallejo, sin auto, en casa de madera, acariciando el éxito después de cantar con unas veinticinco agrupaciones. Concluye el periodista que, en Vallejo, está la esencia del bolero. El presente episodio constituye una semblanza del recordado bolerista, uno de los grandes del género. En el acostumbrado Calendario Musical de Cuba, las remembranzas del flautista Antonio Arcaño, el percusionista y compositor Silvestre Méndez y el inolvidable Pepe Olmo, esa voz de la Orquesta Aragón.Tus comentarios son muy valiosos. Envía un mensaje de texto. Send us a Text Message.Support the show

Join Andrew Dunn and Chris Triebel as they discuss Venom The Last Dance Then stick around for a review of Bolero by Wyatt Kennedy. The Bolero is a kind of dance. There is no dancing in this comic. Unless you dance while you read it. SUBSCRIBE HERE: https://www.youtube.com/c/themedialunchbreak?sub_confirmation=1 BUY SOME MERCH: https://the-media-lunch-break.creator-spring.com Twitter: twitter.com/MediaLunchBreak Patreon: www.patreon.com/TheMediaLunchBreak Youtube: www.youtube.com/c/TheMediaLunchBreak Facebook: www.facebook.com/TheMediaLunchBreak Instagram: @TheMediaLunchBreak Or email us at: TheMediaLunchBreak@gmail.com Listen to and review us on Apple Podcasts, Spotify, and Google Podcasts! The Media Lunch Break on YouTube: www.youtube.com/c/themedialunchbreak Graphic art by: Melinda Filonuk - www.melgraphics.com www.etsy.com/shop/melgraphicscreations Eric Scotolati - https://twitter.com/ericscotolati

Un abrazo musical para el Colectivo Sedajazz de Valencia que ha visto su escuela de música dañada por la Dana, con algunas referencias recientes de su discográfica Sedajazz Records: 'Xano xano' de Martina Sabariego ('Intro', 'Bolero tonal', 'Elvira'), 'El salt del cavall' del cuarteto de Carlos Medina ('L´estrena', 'On estava?', 'Deixar anar part I balada', 'Deixar anar part II samba'), 'Where do we start' de Yuri Storione ('Eu sei que vou te amar') y 'Cool session' de Latino Blanco, Mark Nightingale & Friends ('Five brothers', 'Festive minor'). Escuchar audio

P. Juan Carlos (Ecuador)¿No te entran ganas de gritar a ti, que estás también parado a la vera del camino, de ese camino de la vida, que es tan corta; a ti, que te faltan luces; a ti, que necesitas más gracias para decidirte a buscar la santidad? [Ver Meditación Escrita] https://www.hablarconjesus.com/meditacion_escrita/solamente-una-vez/

#533 Eternal Wee - Richard is back in Bedford, reminiscing about his second appearance on Top of the Pops. His guest is ex-Bedford public schoolboy Al Murray. They chat about how many pints you can drink during Ravel's Bolero, the weirdness of being sent away to boarding school at the age of 9, but the disappointing lack of psychological damage that resulted from this, how Al got into drama and comedy to meet girls, playing Charles II in a Restoration romp, pretending to machine gun trains in a World War Two plane, thirty years of the Pub Landlord and whether he caused Brexit and which PM would Al have sex with if he had to?See a live recording of RHLSTP - https://richardherring.com/rhlstpSUPPORT THE SHOW!Watch our TWITCH CHANNELSee extra content at our WEBSITE Become a member at https://plus.acast.com/s/rhlstp. Hosted on Acast. See acast.com/privacy for more information.

Hour 1 The Mets won again last night but Gio is still being cautious with his expectations for this season because of what happened 2 years ago. Boomer is not being cautious and is all in, but Gio said Boomer got to see the ‘69 Mets and the ‘86 Mets so he has seen them win it all. Jerry is here for his first update of the day and starts with the sounds of the Mets beating the Blue Jays and audio from the afternoon show's excitement with the win. Francisco Lindor hit a HR in the ninth to break up the no hitter. Juan Soto hit a HR in the same at bat he fouled a ball off his foot. Shannon Sharpe said he was embarrassed by the Instagram live that went out with the sounds of him having sex. Deshaun Watson met the media and was asked about the latest lawsuit. Aaron Rodgers called the season a ‘nice, slow Bolero'. In the final segment of the hour, Joe Buck's wife needed foot surgery after he hit her with a golf ball off the tee. Anthony in Belleville calls in and wants credit for stuff. Hour 2 Boomer was comparing Jim Harbaugh and Justin Herbert with Brian Daboll and Daniel Jones. Harbaugh was putting the fire into Herbert's heart, and that's what Daboll needs to do with Jones. Boomer thinks the relationship between Jones and the Giants was frayed because of the offseason Hard Knocks where he knew they were looking for another quarterback. Gio thinks he's a hard worker but he's just not good enough. Jerry returns for an update and starts with Gary Cohen's call of ‘Linsanity', after Francisco Lindor hit a HR in the ninth to break up a no-hitter. The Yankees walked off the Royals with a Jazz Chism single in the 11th. Juan Soto fouled a ball off his foot, then hit a HR. Shannon Sharpe accidentally put the sounds of him having sex on Instagram live. Ochocinco commented on this. In the final segment of the hour, a caller wonders how Gio knew that Sam Darnold would play well this year, albeit one game. Hour 3 Nick Bosa talked about playing the Vikings this week compared with the Jets last week and it sounds like he doesn't think the Jets are very good. There was an open mic at the Raiders facility where a reporter was trashing the team and QB Gardner Minshew. Gio is trying to decide what team to take in the knockout pool this week. A caller is sick of Boomer making excuses for Daniel Jones. Jerry returns for an update and starts with the Mets beating the Blue Jays, 6-2. The Mets were no-hit until the ninth. Lindor broke up the no-hitter with a HR and he thanked police and firemen after the game on 9/11. The Yankees beat the Royals in the 11th on a Jazz Chisholm single. Shannon Sharpe came clean as his Instagram live recorded the sounds of him having sex with a woman. Ochocinco was baffled and disappointed (tongue in cheek). Deshaun Watson met the media after yet another allegation from another woman. Boomer thinks he looks miserable. Daniel Jones is not getting caught up with fan reaction. Joe Buck explained what happened on the golf course when his wife wound up with a broken ankle. In the final segment of the hour, there is a Japanese restaurant in NY that does not allow tipping. We took a call from a restaurant owner who has a problem with Al's complaints about food quality and tipping. Hour 4 Boomer told a story about golfing with Dan Marino years ago where one of the guys in his foursome hit boomer in the testicles with a 200 yard drive. The Shannon Sharpe/Instagram story seems a little fishy as it's not so easy to just accidentally go live. Jerry returns for an update and starts with Shannon Sharpe saying he is embarrassed for having the sounds of him having sex were on Instagram live. Francisco Lindor hit a HR in the ninth to break up the no-hitter and tie the game that they eventually won. Moment of The Day: ‘They're eating the pets, right Eddie?' In the final segment of the show, Jon Bon Jovi talked a woman off a bridge in Nashville. Gio's favorite, Dua Lipa, will be profiled on 60 Minutes this week.

The Mets won again last night but Gio is still being cautious with his expectations for this season because of what happened 2 years ago. Boomer is not being cautious and is all in, but Gio said Boomer got to see the ‘69 Mets and the ‘86 Mets so he has seen them win it all. Jerry is here for his first update of the day and starts with the sounds of the Mets beating the Blue Jays and audio from the afternoon show's excitement with the win. Francisco Lindor hit a HR in the ninth to break up the no hitter. Juan Soto hit a HR in the same at bat he fouled a ball off his foot. Shannon Sharpe said he was embarrassed by the Instagram live that went out with the sounds of him having sex. Deshaun Watson met the media and was asked about the latest lawsuit. Aaron Rodgers called the season a ‘nice, slow Bolero'. In the final segment of the hour, Joe Buck's wife needed foot surgery after he hit her with a golf ball off the tee. Anthony in Belleville calls in and wants credit for stuff.

GOOD EVENING: The show beginsin Pennsylvania, discussing with Salena Zito the political lanscape for the popular young Governor Josh Shapiro of Montgomery County.... CBS EYE ON THE WORLD WITH JOHN BATCHELOR FIRST HOUR 9-915 #KeystoneReport: Josh Shapiro needs a full term before superstardom. Salena Zito, Middle of Somewhere, @DCExaminer Pittsburgh Post-Gazette, New York Post, SalenaZito.comhttps://www.washingtonexaminer.com/opinion/3079107/republican-chairman-says-party-is-ready-to-handle-any-democratic-nominee/ https://6abc.com/post/2024-election-josh-shapiro-president-joe-biden/15054618/ 915-930 #LANCASTER REPORT: Hot air balloon descending and a giant Black Bear perusing. Jim McTague, former Washington Editor, Barrons. @MCTagueJ. Author of the "Martin and Twyla Boundary Series." #FriendsofHistoryDebatingSociety https://lancasteronline.com/news/politics/lancaster-county-republicans-divided-over-pa-s-new-47-6b-state-budget/article_78a901ea-4089-11ef-8aec-272c41415596.html 930-945 #SCOTUS: The opioid decision satisfies no one but the Sacklers. Richard Epstein, Hoover Institutionhttps://www.hoover.org/research/upending-sackler-bankruptcy 945-1000 #POTUS #SCOTUS: Amendment to set age limits for office. Richard Epstein, Hoover Institutionhttps://www.nytimes.com/2024/07/12/us/politics/hakeem-jeffries-biden-democrats.html SECOND HOUR 10-1015 #PacificWatch: #VegasReport: Elvis Presley impersonators in a heat wave. @JCBlisshttps://www.nytimes.com/2024/07/11/us/las-vegas-heat-houston-power.html 1015-1030 #ITALY: Ravel's Bolero in San Marco Square. Lorenzo Fiori, Ansaldo Foundationhttps://en.wikipedia.org/wiki/Piazza_San_Marco 1030-1045 1/2: ##EDUCATION: University faculties are one-sided & What is to be done? Peter Berkowitz, Hoover Institution.https://www.realclearpolitics.com/articles/2024/07/07/roots_of_and_remedies_to_americas_illiberal_education_151212.html 1045-1100 1/2: ##EDUCATION: University faculties are one-sided & What is to be done? Peter Berkowitz, Hoover Institution.https://www.realclearpolitics.com/articles/2024/07/07/roots_of_and_remedies_to_americas_illiberal_education_151212.html THIRD HOUR 1100-1115 1/8: The Wide Wide Sea: Imperial Ambition, First Contact and the Fateful Final Voyage of Captain James Cook by Hampton Sides https://www.amazon.com/Wide-Sea-Imperial-Ambition-Contact/dp/0385544766/ref=tmm_hrd_swatch_0?_encoding=UTF8&dib_tag=se&dib=eyJ2IjoiMSJ9.xvSnWMwZwkRk3nB_oha-u7YL0k9kTC4voIQCoSWDz75eZXBRk_ZvRqUZ_P6pMaemKHJ8AhEdiyCpLrikQsp9iSIHNpX0v0n71kJqmCUW1VujrRMuDnenOyoWd5NtaDroImV4hSJ-hXf41L0HQmBS2q4Ws_PUqdVAXpvxskDgbzkPGE54c4xCqXxznyoRsahmmC7zXsNKkmipQCOKWZt728zHdG1ntVV4xSjkKJdX0v4.qQvWTGgLh4U5mw9t7ELNeecNVMkHQl35VNFyULPNX4g&qid=1720822146&sr=8-1 1115-1130 2/8: The Wide Wide Sea: Imperial Ambition, First Contact and the Fateful Final Voyage of Captain James Cook by Hampton Sides 1130-1145 3/8: The Wide Wide Sea: Imperial Ambition, First Contact and the Fateful Final Voyage of Captain James Cook by Hampton Sides 1145-1200 4/8: The Wide Wide Sea: Imperial Ambition, First Contact and the Fateful Final Voyage of Captain James Cook by Hampton Sides FOURTH HOUR 12-1215 #RUSSIA: #TURKEY: #NATO: US seeks to compete with ROSATOM in Istanbul. Andrea Striker, FDDhttps://www.fdd.org/analysis/2024/07/10/u-s-considers-nuclear-cooperation-with-turkey-as-congress-tees-up-sanctions/ 1215-1230 #COLOMBIA: Lawfare and M-19. Mary Anastasia O'Grady, WSJ https://www.wsj.com/articles/foreign-lawfare-comes-to-u-s-courts-legal-courts-politics-latin-america-colombia-cc034b83?st=52c85gk1lsps7gy&reflink=article_gmail_share 1230-1245 SPACEX: Rare fail. Bob Zimmerman, BehindtheBlack.com https://behindtheblack.com/behind-the-black/points-of-information/spacex-launch-experiences-a-failure-of-upper-stage/ 1245-100 am WEBB: Exoplanet with a nitrogen atmosphere. Bob Zimmerman, BehindtheBlack.comhttps://behindtheblack.com/behind-the-black/points-of-information/webb-an-exoplanet-in-the-habitable-zone-with-a-possible-nitrogen-co2-atmosphere-and-water-ocean/ 1945 Lancaster County

#ITALY: Ravel's Bolero in San Marco Square. Lorenzo Fiori, Ansaldo Foundation https://en.wikipedia.org/wiki/Piazza_San_Marco 1900 Bologna