Podcasts about embryonic stem cells

Stem cells are unique cells that have the ability to divide and differentiate into various specialized cell types in the body. There are two main types of stem cells, Embryonic Stem Cells and Adult Stem Cells. Embryonic Stem Cells are derived from the early stages of an embryo and have the potential to develop into any cell type in the body. Adult Stem Cells are found in mature tissues and organs and can differentiate into specific cell types within that tissue or organ. Stem cells can replace damaged or diseased cells, accelerate wound healing and restoring organ function ,target and destroy cancer cells while preserving healthy tissue and much more! We will discuss everything about stem cells that you need to know and have to know before seeing a doctor.

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As our bodies age, our cells are aging with us, and the messages they produce are decreasing. While growth factors have been used to take the message of youthful cells and use them to stimulate the skin, exosomes offer a more complete, natural, and protected version of those messages. Scientific researcher Dr. Jordan Plews, CEO and co-founder of ELEVAI Labs, joins Dr. Bass to discuss what's happening in the space of exosomes, stem cells, and regenerative medicine as a whole. Through experiments with stem cells, Dr. Plews and his colleagues discovered that the cells provided some benefit, but they weren't sticking around or fixing problems such as wounds. This led to the discovery of exosomes, nano-packages that the body uses to send signals to cells. When searching for the best exosomes to separate, Dr. Plews and his team found that by taking exosomes from age zero stem cells, they can safely be put back into the body to “remind it how to be young again.” Drawing on his two decades of research in the study of stem cells and regenerative medicine, Dr. Plews explains what exosomes are, how they were discovered, the potential they hold, and how we may be using them in medicine going forward. About Dr. Jordan Plews Dr. Jordan Plews is the co-founder and CEO of ELEVAI Labs, Inc. He has dedicated nearly 20 years to the study of stem cells and regenerative medicine. Following many years investigating the use of various types of stem cells on injury and degenerative diseases, he has gone on to build and lead teams, setting up stem cell culture labs and developing stem cell-based regenerative medicine solutions before pivoting into aesthetics. Learn more about Dr. Jordan Plews and ELEVAI Labs, Inc. Follow Dr. Plews on Instagram   About Dr. Lawrence Bass Innovator. Industry veteran. In-demand Park Avenue board certified plastic surgeon, Dr. Lawrence Bass is a true master of his craft, not only in the OR but as an industry pioneer in the development and evaluation of new aesthetic technologies. With locations in both Manhattan (on Park Avenue between 62nd and 63rd Streets) and in Great Neck, Long Island, Dr. Bass has earned his reputation as the plastic surgeon for the most discerning patients in NYC and beyond. To learn more, visit the Bass Plastic Surgery website or follow the team on Instagram @drbassnyc Subscribe to the Park Avenue Plastic Surgery Class newsletter to be notified of new episodes & receive exclusive invitations, offers, and information from Dr. Bass.   

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Amander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38334]

Gideon Krausz is CEO of the Cellular Renewal Clinic in Tijuana, Mexico. Dr. Adrian Robinson is an expert in Regenerative Medicine, Anti-Aging, Intra-articular Joint Injections, and Acupotomy. *Disclaimer* - Please speak with your doctor prior to seeking stem cell treatment to ensure it is a good, and healthy fit. SHOW SPONSORS:  Please support this podcast by checking out our sponsors: 

I thoroughly enjoyed the second part of my interview with life and behaviour philosopher, science guru extraordinaire, and all-round awesome dude, Dean Kilby. And I know you will love listening, too. If you haven't listened to the first part of my interview with Dean, please do so now. Click to Listen Part 1In the second part, we discuss the importance of our mind set, our thinking patterns and how to get to that higher and healthier level of thinking.The good news is, it's not difficult at all and with just a few reminders like these below, I've been on my way to higher level thinking since recording the episode.Prioritise opportunities to talk out ideas with other people, as real thinking often happens in conversation.Consider incorporating environmental stimuli that facilitate high levels of thinking, such as going for a walk in nature or spending time in silence.Utilise tools like a whiteboard to help facilitate brain dumps and visual organisation of thoughts.These actions can help facilitate deeper thinking and greater creativity, which can be difficult to achieve when solely relying on internal thought processes. By prioritising these strategies, we can all increase our capacity for generating innovative ideas and solutions.The Power of Mindful Decision-MakingMaking impulsive decisions based on our internal state can often result in negative consequences. This is especially true when we are feeling unhappy or stressed. In these situations, we are more likely to make rash decisions that can create even more problems, leading to further stress and dissatisfaction with life.However, it's not just the immediate decision that can cause problems. It's the accumulation of issues that can make us feel overwhelmed and helpless, as if we are trapped between a rock and a hard place. This can lead to feelings of resignation and cynicism, leaving us wondering how we got to this point.I created my Unique Beauty Affirmation cards as a gentle reminder for creating better mindsets and healthier and happier lives.  Finally, listen here to find out how our gut microbiome makes us behave in a certain way.Dean and I discuss a fascinating recent development around stool transplants. The idea that your gut is your second brain, is certainly gaining traction through scientific proof.Another indicator why your overall health in important in helping you make decisions that will make you happier and healthier. LINKSFor more info about Dean Kilby, check him out here:www.deankilby.comAnita's Socials:www.facebook.com/anitaeastauthor/www.instagram.com/anitaeast_www.youtube.com/channel/UC_bXeZS4a9OOFZUVAw29Y7Qwww.linkedin.com/in/anitaeastwww.twitter.com/AuthorAnitaEastBook and Online Shophttps://www.anitaeast.com/beautiful-unique-faces-book-second-editionhttps://anitaeast.com.au/shop/

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.06.26.546513v1?rss=1 Authors: Spits, C., Lei, Y., Al Delbany, D., Krivec, N., Regin, M., Couvreu de Deckersberg, E., Janssens, C., Ghosh, M., Sermon, K. D. Abstract: Human pluripotent stem cell (hPSC) cultures are prone to genetic drift, as cells that have acquired specific genetic abnormalities experience a selective advantage in vitro. These abnormalities are highly recurrent in hPSC lines worldwide, but currently their functional consequences in differentiating cells are scarcely described. An accurate assessment of the risk associated with these genetic variants in both research and clinical settings is therefore lacking. In this work, we established that one of these recurrent abnormalities, the loss of chromosome 18q, impairs neuroectoderm commitment and affects the cardiac progenitor differentiation of hESCs. We show that downregulation of SALL3, a gene located in the common 18q loss region, is responsible for failed neuroectodermal differentiation. Knockdown of SALL3 in control lines impaired differentiation in a manner similar to the loss of 18q, while transgenic overexpression of SALL3 in hESCs with 18q loss rescued the differentiation capacity of the cells. Finally, we show by gene expression analysis that loss of 18q and downregulation of SALL3 leads to changes in the expression of genes involved in pathways regulating pluripotency and differentiation, including the WNT, NOTCH, JAK-STAT, TGF-beta and NF-kB pathways, suggesting that these cells are in an altered state of pluripotency. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Feeling Lost in a World of Endless Health Advice? Here's What You Need to KnowToday's world is constantly bombarded with health advice that promises to improve our physical and mental well-being—from fad diets to miracle supplements, figuring out what works and what doesn't, can be overwhelming. You're not alone if you feel lost amidst this sea of information. In my podcast Difficult Conversations About Beauty, we dive into some hard-hitting topics with science and health expert Dean Kilby to explore how our diets and mindset affect our overall health and beauty. We'll also learn practical tips to overcome common roadblocks and shift towards a healthier lifestyle.My interview with Dean revealed some eye-opening insights about our relationship with food and our bodies. Dean suggests that we often eat poorly because we're disconnected from our physical selves. Instead of viewing our bodies as a "skin bag," he encourages us to approach our health objectively. This mindset shift can lead to a more intuitive, mindful approach to eating, where we listen to our bodies and nourish them accordingly. Dean reminds us that our bodies are not just a means to an end but an integral part of our well-being.Dean also emphasized the importance of movement in our daily lives. He notes that we often sit for prolonged periods, leading to stiffer joints and poor posture. Dean suggests incorporating more natural movement throughout the day, such as taking short walks or doing gentle stretches. This keeps our bodies limber and boosts our mental clarity and mood. Dean describes how our physical and mental well-being go hand in hand and that caring for both is crucial for holistic health.One significant takeaway from Dean's interview is the idea of "stop caring so much.' We spend so much time caring about our thoughts and feelings, but they're just that, thoughts and feelings. They are not us. They do not define us. This may sound flippant, but it's a powerful mindset shift that can help us overcome roadblocks in our health journey. Dean explains that we often create stories in our minds that hold us back from making positive changes. We may believe we're not disciplined enough or that a healthy lifestyle is too expensive or time-consuming. However, Dean suggests that we can choose to let go of these stories and focus on our "why"—our underlying motivation for wanting to improve our health. Doing so allows us to break through these roadblocks and create lasting change. Finally, Dean emphasizes the importance of being up to something bigger than ourselves. He notes that we see a greater purpose in our health journey when we shift our focus from internal struggles to external impact. This purpose can provide the motivation and inspiration to continue pursuing a healthier lifestyle, even when challenging. Dean encourages us to find a cause or community that resonates with us and use that to drive positive changes.In summary, feeling lost in a world of endless health advice is a common struggle many faces. However, by adopting a mindset of objectivity, incorporating movement into our daily lives, embracing the idea of "stopping giving a f*," and finding a greater purpose, we can overcome roadblocks and make lasting changes to our physical and mental well-being. Dean's insights provide a refreshing perspective beyond quick fixes and instead focus on holistic health. So the next time you feel overwhelmed by health advice, try applying some of Dean's tips and see how they positively impact your life.LINKSFor more info about Dean Kilby, check him out here:www.deankilby.comAnita's Socials:www.facebook.com/anitaeastauthor/www.instagram.com/anitaeast_www.youtube.com/channel/UC_bXeZS4a9OOFZUVAw29Y7Qwww.linkedin.com/in/anitaeastwww.twitter.com/AuthorAnitaEast

To bring us into the future of stem cells in aesthetics, regenerative medicine pioneer Dr. Steve Cohen joins Dr. Bass for a conversation about the future of this innovative area of medicine.  Because stem cells are not fully differentiated, they have the ability to turn into a muscle cell, a skin cell, or a blood vessel lining cell. This versatility allows them to be used in plastic surgery, where benefits include improving blood supply, making new blood supply, reducing inflammation, and repairing tissue, to name a few. In the future, stem cells might be used for such applications as rehabilitating the tissue during breast reconstruction before putting a breast implant in, healing or reversing radiated tissue in head and neck cancer patients, or in combination with laser treatments for the best possible skin resurfacing results.  Dr. Cohen and Dr. Bass share how stem cells can be incorporated today to get ideal results and how they might help reduce the complexity of procedures and increase longevity of results in the future.   About Steve Cohen, MD Dr. Steve Cohen is a San Diego-based and internationally recognized plastic surgeon, inventor, author, artist, and founder of FACES+. He currently specializes in cosmetic and craniofacial surgery. Learn more about Dr. Cohen's practice, FACES+  https://www.facesplus.com/  Read more about Dr. Steve Cohen  https://www.facesplus.com/about/dr-steven-cohen/   About Dr. Lawrence Bass Innovator. Industry veteran. In-demand Park Avenue board certified plastic surgeon, Dr. Lawrence Bass is a true master of his craft, not only in the OR but as an industry pioneer in the development and evaluation of new aesthetic technologies. With locations in both Manhattan (on Park Avenue between 62nd and 63rd Streets) and in Great Neck, Long Island, Dr. Bass has earned his reputation as the plastic surgeon for the most discerning patients in NYC and beyond. To learn more, visit the Bass Plastic Surgery website or follow the team on Instagram @drbassnyc Subscribe to the Park Avenue Plastic Surgery Class newsletter to be notified of new episodes & receive exclusive invitations, offers, and information from Dr. Bass.   

Stem cells are the building blocks for the human body, and without stem cell activity, the body can't repair, regenerate or renew itself. Stem cell activity decreases as we age, but there are several ways to reverse the effects of that biological process. In today's episode, I share simple, cost-effective wellness protocols that can help you create a healthy environment for stem cells to thrive. There are three main types of stem cells and different therapies associated with them. But, before you go down the path of procedures that cost tens of thousands of dollars, there are things you can do everyday to optimize healthy stem cell activity. Between your diet, exercise, and stress management, your experience of aging is within your control. One of the tools that has been instrumental for me in my journey of feeling younger while growing older has been using LifeWave patch technology. In this episode, I unpack the benefits of these patches and announce a giveaway I'm doing so you can try them out. Here's how to enter to win a 30-day supply of LifeWave X39 or X49 stem cell activation patches: Leave a review on Apple Podcasts. Screenshot your review and send it to dana@danafrost.com or via Instagram DM @danafrost.  Follow me on Instagram, link to this episode on your Instagram story and tag me in that story. The giveaway closes on May 8th, so be sure to enter before then! Listen in to learn more about what stem cells are and how you can continue to promote stem cell activity as you age. If you are enjoying these conversations, please subscribe and spread the love by leaving a review and sharing it with your friends.Listen to the episode on Apple Podcasts, Spotify, Google Podcasts, Stitcher, TuneIn, or on your favorite podcast platform. Topics Covered: The role that stem cells play in overall health and quality of lifeKey lifestyle changes that can promote the activation and growth of stem cellsThe pros and cons of different stem cell therapies that are available right now Non-invasive and convenient ways to support the body's natural production of stem cells. The changes that I've noticed in myself since I started using LifeWave patches Resources Mentioned:Episode 24. DNA Testing and Your Health with Kashif Khan, CEO and Founder of The DNA CompanyEpisode 60. The Ten Hallmarks of Aging with Chris MirabileLearn more about LifeWave   Get in Touch: My WebsiteInstagramSpecial offers: Download the Daily Vitality eBook at danafrost.com/daily-vitality/Credit:Podcast Production by the team at The Wave PodcastingMusic by Phoebe GreenlandPhotography by Amy Boyle PhotographyPodcast art by  SimplyBe. Agency

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.28.530008v1?rss=1 Authors: Kodera, T., Takeuchi, R. F., Takahashi, S., Suzuki, K., Kassai, H., Aiba, A., Shiozawa, S., Okano, H., Osakada, F. Abstract: Studying the non-human primate (NHP) brain is required for the translation of rodent research to humans, but remains a challenge for molecular, cellular, and circuit-level analyses in the NHP brain due to the lack of NHP brain system. Here, we report an NHP cerebral model using marmoset (Callithrix jacchus) embryonic stem cell-derived cerebral assembloids (CAs) that recapitulate inhibitory neuron migration and cortical network activity. Cortical organoids (COs) and ganglionic eminence organoids (GEOs) were induced from cjESCs and fused to generate CAs. GEO cells expressing the inhibitory neuron marker LHX6 migrated toward the cortical side of CAs. COs developed their neural activity from a synchronized pattern to an unsynchronized pattern as COs matured. CAs showed mature neural activity with an unsynchronized pattern. The marmoset assembloid system will provide an platform for the NHP neurobiology and facilitate translation into humans in neuroscience research, regenerative medicine, and drug discovery. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.08.519620v1?rss=1 Authors: Spildrejorde, M., Samara, A., Sharma, A., Leithaug, M., Falck, M., Modafferi, S., Sundaram, A., Acharya, G., Nordeng, H., Eskeland, R., Gervin, K., Lyle, R. Abstract: Background: Several epidemiological studies have found associations between long-term prenatal exposure to paracetamol and neurodevelopmental outcomes in childhood. Pharmacoepigenetic studies have identified differences in DNA methylation (DNAm) in cord blood between exposed and unexposed neonates. However, the causal implications and impact of prenatal long-term paracetamol exposure on brain development are not known. Methods: We exposed human embryonic stem cells (hESCs) undergoing in vitro neuronal differentiation to daily changes of media containing amount of paracetamol corresponding to human foetal exposure with maternal therapeutic doses. An integrated multi-omics approach was used to investigate epigenetic and transcriptomic effects of paracetamol on the early stages of human brain development. Results: Multi-omics analyses of DNAm, chromatin opening, and gene expression identified dose-dependent effects on cell proliferation and maturation. We found differentially methylated and/or expressed genes involved in signal transduction, neurotransmitter secretion and cell fate determination trajectories. Integration of single-cell RNA-seq and ATAC-seq showed that paracetamol-induced changes in chromatin opening were linked to transcription. For example, EP300 encoding a histone acetyltransferase and H3K27ac were linked to many putative cis regulatory elements and downregulated upon paracetamol exposure. Some of the genes are involved in neuronal injury, response to toxic insults and development-specific pathways, such as KCNE3, overlapped with differentially methylated genes previously identified in cord blood associated with prenatal paracetamol exposure. Conclusion: We identified dose-dependent epigenetic and transcriptional changes in hESCs undergoing neuronal differentiation after paracetamol exposure. The overlap of differentially methylated genes with our previous analysis in cord blood from children exposed to paracetamol during pregnancy could suggest a causal role in impaired neurodevelopment. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This episode is also available as a blog post: https://mdforlives.blog/2022/03/29/complex-kidney-tissue-generated-entirely-from-mouse-embryonic-stem-cells-for-improved-kidney-research-and-eventually-artificial-kidney-transplantation/ --- Send in a voice message: https://anchor.fm/mdforlives/message

Dr. Janet Rossant, senior scientist at the Hospital for Sick Children, and president of the Gairdner Foundation, joins us to dispel myths about aborted fetal cells or embryonic stem cells used in the COVID-19 vaccines, and explains how these cell lines are applied in science. See omnystudio.com/listener for privacy information.

Hello. Hello, please help me welcome Dr. Ross Carter, as he's been in private practice since 1996 in Atlanta, Georgia, and now resides in west Palm beach, Florida. He's a specialist in helping minimize suffering from joint and spine pain, regenerative and chronic disease due to hidden weaknesses in our bodies. He does this by using regenerative nanoparticles to find and heal those weaknesses before they become problematic. He works as a health consultant at the world famous Hippocrates Health Institute, which is the largest natural food health Institute in the country. He has one of the largest regenerative medicine podcasts in the world, The Regenerative Warrior Podcast and Show, which can be found on YouTube and Apple podcasts. He is a number one best-selling author of: Doc Stem Cell: how stem cell therapy can eliminate knee, hip, and shoulder pain and the Million Dollar Business Card- create your authority, attract ideal clients and 10 X your income, no matter what your business is. He's also a national and international speaker. He has received his fellowship in stem cell therapy from the American Academy of Anti-aging Medicine in 2017. And he is also a doctor of indigenous medicine, which is a holistic approach, which considers your body as sum of physical, emotional, spiritual, and intellectual wellbeing, as well as your place in the community. His expertise involves teaching on restorative sleep and sleep coaching as well as many other kinds of regenerative medicine procedures. Welcome Dr. Carter. It's such a pleasure to have you here today. My pleasure to be here. Thank you for having me. Can you explain to our listeners what exactly, what are stem cells and why do we hear about them so much? Well, to give you basically a definition of stem cells, it is an undifferentiated cell that can become any other type of cell that it wants to become, whether it be a muscle, a ligament, a bone cartilage, blood cell. So it's, it's really a blank cell that that can become something else. And we have them in our body and they're there to help our body repair itself. Our body is constantly getting damaged and when we have cells that die every day, we have about a hundred billion cells that die every single day. And if you pick up your phone, basically that's about the weight of the amount of cells that need to be replaced every single day. So the stem cells are really in charge of that feature of our body to stimulate the repair and replacement of all the damaged cells. So that's the essence of what a stem cell is. That is so interesting.  You're saying it can be molded to a specific use. Right, that's that's its purpose. It can become more of itself or it can delineate into one specific cell line. So for example, we're completely made out of cells and we have skin cells. We have eye cells, we have, T cells. We have cells that are for our blood, We have lung cells, we have liver cells. So we have a variety of different types of cells and those types of cells need to be replaced with the same type of cell. So, these blank cells get us some type of information or signal, and then they become the type of cell that is needed,  to replace , the damage. That is so fascinating. So where do you get stem cells from and what's the difference between human embryonic stem cells and then adult stem cell? Where do we get stem cells from? Well, we have them naturally in our body that if they weren't working and we didn't have any, we would die. So we naturally have a storage of a lot of stem cells in our body. As we get older, the amount of stem cells that we have definitely goes down a lot and it does, affect our ability to heal ourselves. So, there are tons of different cells. Now, when you're talking about treatment, there's really two areas. You can either get them from your own body or you can get, um, donated from somebody. So for example, we have a lot of different stem cells in our, in our bone marrow. So that's a commonplace for where we can get some stem cells. Also, we have it in our fat as well, or adipose tissue, and we can get those regenerative cells from those locations. But there are other locations, the primary areas that we typically get them from our own self. Now, sometimes as we get older, the ability of ourselves to repair and stimulate repair, um, definitely decreased tremendously. And because of that, that's when re other sales from other people may be of better benefit. And the most common place that we get them is from placental tissue back about 20 years ago, there was, there was some controversy, regarding in the use of embryonic stem cells and an embryonic stem cell is after the egg is fertilized. The cell starts to grow into a mass and they usually get those cells at a very early stage, you know, and that's obviously going to prevent the, the cells from becoming a being . And they use these for different experimentations. It's sometimes is used now, but very, a lot less common. Um, so that was very controversial because it obviously killed the potential baby. Now there's something called adult stem cell. And an adult stem cells is a little misleading because it's, when, when you're born, they're now considered adult stem cells, even though you're not in an adult, but it's post pregnancy, I guess. These adult cells, typically only become one different specific type of tissue and not like an organ system or another body. Like they can with embryonic, they can create a whole new body, like a clone for you. So, the adults stem cells are the ones that we get from our body. Now, the placental ones, um, typically come from a placental tissue. So when a woman is having a baby, the placenta is surrounding and protecting the baby. And when the baby comes out, the placenta does too. And that's usually either discarded or a lot more times it's saved w  than it was before. And those cells, that's little regenerative factory that, that comes out. We can utilize those again and recycle those so that we can get a lot of the benefits, from those cells and those are placental. That's funny that you used the word recycle because that's literally what I was thinking of. I think that's kind of cool. Something that was going to go in the trash can actually be recycled and help people , give him less pain and live a better life. That is amazing. And then it's like kind of being a donor without having to die. That's awesome. I love it. Why did doctors and scientists use stem cells? and tell us about the body's ability to accept or reject the stem cells. So why don't we use them? I've mean they stimulate repair and regeneration of the body is the prime. That's their primary reason.  So that's what they're utilized for, but we can in laboratories, they can do a lot of things that don't naturally happen in the body.  They can regenerate and create a whole new organ system and, and things like that, that's not what usually happens in the body so they can do a lot of things with science now that, you know, as, as time progresses, they, they just develop various new techniques and new methods of using these stills. And actually, what what's really cool is recently they've they figured out how to. The cells function in the body, which was different than, than what most people used to think. Now, what most of the majority of people in this industry used to think is that a stem cell itself would be the cell that repairs. The damage, but actually it's not exactly how it works. It actually stimulates the repair of damage and it doesn't actually do the repair itself. So it, we have what are called progenitor cells, which are really the tissue specific, stem cells in this case, but they're called progenitor cells and they make more of their own type of tissue. Meaning you'll have skin cells that make more skin cells, right. It doesn't want to make a heart cell. So those are very specialized types of cells and a stem cell basically orchestrates the repair. So if you damage your skin, the stem cells come to that area and then they tell all the spells, uh, what to do and how to repair. And they use little signaling to do that. Almost like a domino effect, it gets in there and makes a reaction like causes the other cells to do a repair job. Correct. It does. It stimulates the other cells. It sends information. It sends like a recipe of what needs to happen. this cell is going to communicate to this cell these little tiny chemical messages. And they're in, they're in a protective little bubble and it travels from this cell to this cell and it just floats over and that cell takes it in and then it has instructions or a recipe of what that cell wants the other cell to do. And so that's how cells work cells are primarily protein factories. They create proteins constantly, and that determines the function of the cell. So. You the cells say, okay, this is what we need you to do. And it sends the little instructions and that, that cell text and the instructions for each the instructions, it says, okay, now that this is what we're making and that's how the cells actually function. And they stimulate repair is through these instructions. So what's cool. Is that recently we found that we can just take the instructions and not even use the cell itself. Wow. And take just a concentration of a bunch of instructions or recipes and inject that into an area or the body. And just with instructions, it will stimulate that same type of response without a live cell. Because when we take cells from one part of the body and put them in another, they don't like that so much. Another thing, if you take someone else's cells and putting them in your body, Your body is going to kill those, they're going to be rejected. Maybe not initially, , but they will be found by the immune system and they're destroyed, but they have the ability to stimulate, send those little tiny bubbles I was telling you about so that it, they can stimulate the repair of the cells that are damaged. So fascinating. Holy cow! It's a, it's a new that's where we talk about nanoparticles. Nanoparticles are the things that are, that that really are molecules that stimulate the, are the recipes, it tells the cells what to do. That's incredible. And I love, I love the fact that you can do it without the cell, which seems to be the hinderance of it. It is, it's the most common problem because when you take cells and if you take a lot of them, you, your body's going to have a reaction and a rejection component, and that's, that's a problem. But what, you know, what's interesting is they're using stem cells and these signaling factors to decrease the host reaction when you take on other cells from other people. So they, they have a way of modulating the immune system, basically it's changing it so that it doesn't, it doesn't attack immediately. Like, if it was just a regular cell, it would be immediately, identified and attacked. I know people will drugs to try to help prolong that. And is it a time thing where the stem cells enter and that the message is trying to get out there and you don't want the body to reject it. Well, when someone has a transplant of an organ, that they have to take a lot of drugs for the rest of their life, so that the body doesn't reject that organ because it naturallywill. And what kind of risks are associated when you get stem cells? Well, it depends a lot of factors that go into that. What the type of cells you're using, where are they from? Are they from a laboratory or are they from a person? How have they been processed? There? There's a lot of factors that go into determining, you know, What's going to happen. Overall, the safety record for most of these, products and used as a therapy is really super high they're they're fairly, they, they don't usually cause a stimulation of problems that usually help enumerate them.  And people can donate correct, like the bone marrow ? Yeah, there are companies that do except, donations of different stem cells  and yeah, I don't do that. One other question,  I just want to get into the sleep a little bit because I love, I love that whole thing. People don't realize how valuable sleep is to their lives.  So what are your favorite tidbits one that you can share that most people probably haven't heard of in regards to protecting that quality sleep ? The primary problem that I see the majority of people have is they've messed up their circadian rhythm. The circadian rhythm is a natural rhythm of the body. And, um, because of technology like computers and televisions and light bulbs and these things that we utilize at night,  it affects our circadian rhythm. Our circadian rhythm is really controlled by the rising and the setting of the sun . And it's really the light that we're getting in our eyes. Ideally, what should happen is that when we wake up in the morning, we should get, you know, bright sunlight. It tells the brain that it's daytime not to create any melatonin. And then as the sun goes down, the, you should be in a dark place where the melatonin,  is being produced because the brain says, Hey, it's time to get ready to go to sleep. The challenge we have in regular society, and our society is that we have lights from phones, we have lights from our TV. We have just our light from our regular bulbs.  And what that does is it tells the brain that it's still daylight outside. Uh, even though it's not, and it tricks our circadian rhythm to believe that it's not time to go to bed and then it throws it off. You know, most of us as, as children, we're able to sleep pretty well. And we unlearn that ability, a lot of us over time because of things that happen as stresses that happen in our life. And then we screw up our ability to sleep well. And so working when, when you first start working on, uh, your sleep, the best area to start with is working on the light and dark that you receive throughout the day. So here are the easy ways to do, that when you wake up in the morning and you should wake up at the same time and go to bed at the same time. Easier for your body to stay on that rhythm. When you wake up in the morning, you need to go outside, get some air, gets them sunlight. It's the blue light, really the primary light that you're, that you're wanting to get that into your brain so that it can clear up some of the, some sleep that you may, you may be feeling a little sleepy going outside helps that, but when it comes to night, If you go to bed, let's say at 10 30, ideally what you want to do about two hours or so before you go to bed, you want to put it  sunglasses like a light blocking glasses, blue light blocking glasses are usually the best and make sure they're tend to not like these clear ones, because you'll see some, they say blocks blue light and, and it'll be these glasses. And then you get something blue and you can see it's blue. And you're like, well, that's not blocking can get very effective. True. The funny thing, the way to test your glasses. Put them on and look at blue light. Like if you're, if you have a microwave oven with time or something , if you look at that, if you put your glasses on, can you see it? If you can see it, it's not blocking all the blue light, right? If it does, if you don't see anything, which is what you're wanting. Nothing definitely is doing a good job. So that's a good way to test those. So put those on two hours before you go to bed every night. Every night before I go to bed, I have you, you create routines as well, routines and rituals to turn down your body, to relax your body so that it's not overly stimulated, don't watch scary movies or a lot of crazy dramatic TV before you go to bed. It just good for you. So decrease the stimulants that you're doing in your life. So you wind down, put our routine in, maybe should read or do yoga, or those are the things I do, or like a hobby, like, I like to play my guitar. That's my practice time. Every night I have it scheduled. And so I go through these routines every night and that way I can go to sleep really easily. And then I get plenty of sleep because my body is in a rhythm. As long as it keeps in this rhythm, then you're doing a lot better. It's when you stay up really late or go drink, a lot of alcohol drink, too much stimulants, do things that you shouldn't, eat a big meal. Uh, things like this, you should not do before you go to bed. Right. These things can really affect your circadian rhythm. And so the easiest way, like I said is to, to work with the light and that will help dramatically improve the ability of your body to go to sleep. Are you a fan , I believe it's red light, isn't it? A lot of people will use red light at night. I'm like put a red light bulb in table lamps and not use overhead lighting . So they're more red. Yes, absolutely. And they don't affect, your circadian rhythm. So there's true dark has a light bulb, I actually used that one in my room at night when we're going to bed. I'll turn that on so I don't have to wear the glasses. Right, right. Yeah. That's a, that's a good way to do it. Yeah. Another question about melatonin, I know, when your circadian rhythm is correct that your body releases out at the correct time in the evening. Um, when you take melatonin like an artificial supplement of melatonin, I've read that, that messes up your body's natural ability to then produce melatonin. But how do you feel about that? To some degree? That could be the case. It's really, I haven't read a lot of things. That say negative things about use of melatonin, but you want to keep your dosage kind of reasonable three milligrams or less. It is a great antioxidant in addition to helping you sleep. So I've seen many clients that use melatonin every night, for basically their entire life and they don't really have any challenges with that. So can it affect your ability to make your own probably, but just as long as you don't get crazy with it, I think it's okay. Well, I have definitely big time rituals and routines, but, I drink tea that has passion flower in it  and I take Ashwaganda. And I tell you what, it's like shutting off a light bulb within an hour. My lights are out. It works beautifully every night.   Well I'd say I take those supplements actually passionflower, uh, ashwagandha.  The other one  chamomile.  There's a lot of them, there's even, some that help with the rise of cortisol. If you, if you're a little bit stressed, there are something called milk, milk, peptides, or casein peptides,  which you could get the supplements for online. And those are good for reducing the, the cortisol response to increase cortisone, I'm saying that wrong to increase melatonin supplement that I like, that's natural that makes your own has to do with sour cherry powder. Sour cherrypowder is good to stimulate your own melatonin production. If you're low in melatonin, this'll help stimulate it. I've heard a lot of things about the sour cherry. I didn't associate it with the melatonin production. That's very interesting. So would you kindly tell our listeners where they can locate you so they can get more information? Sure. Sure. They can just simply go to my website. This is my name, Dr. Ross carter.com. There they can, they can find everything they need . If they have questions, they can set up a time to chat and, yeah, it's really simple. Such an exciting arena, the whole stem cell thing. I mean, what a cool job to have to try to help people stay out of pain and live better, longer, that must be very rewarding. I it's all such a blessing. Let me, let me throw something in.  If your listeners are really interested in learning about, uh, regenerative procedures, as well as stem cells and the signaling factors I mentioned, because medicine is going in the way of regenerative or RNA is really the major driver here and that's what our vaccine is made out of. It is an RNA in a protective coating. So you want to learn how more about that in a, in a simple way. I just published a book about it. It's called Bio Hack Aging, and it just became a best seller yesterday, actually on. Yeah, very happy. I did a launch yesterday and it became a bestseller quick. And, uh, so it's called Bio Hack Aging and right now I have a special on it, the ebook, I have it at 99 cents. It'll go back up to $10 for the ebook, probably tomorrowor the next day. But if you go now that you can, uh, you can get it for 99 cents. It's on Amazon, just type in BIOhack aging, and you'll find it. I spent two years researching for this. That's like the deal of the day people.  I will so be going to do that right after we get off the air here. I definitely will be purchasing that! You know, I love when, when you can find out the things that make you live better, it's not necessarily how long you live, but to me, it's how you live with the energy and the quality of life, that's so important. So I hope, my listeners do as well. Well, they want to learn how to stop the aging process, this is it, I'll give you a quick summary. There's three things that cause us to age. The three things are this, your daily metabolism, meaning your cells are functioning that causes damage to your body, stress, which is physical, emotional, and chemical, and our epigenetic changes or the, the changes of our genetics over time. Right? All three of those combined cause damage to our body. As, as we get older, the ability to repair that damage decreases, eventually it reaches a threshold and then we start developing conditions like, you know,  like back pain or arthritis or some type of conditions. And that is really when we're truly aging is when our, our repair system can't keep up with the amount of damage that we're sustaining. So I teach a way it's simple one procedure that can undo that, that can stimulate our body to repair like it used to when we were younger and not like, if you want, like, not like a 51 year old. Right. That's awesome. Okay. Last question on my question. Um, if there is one thing you could eliminate from this world, what would it be and why ? So one thing I would want to eliminate in this world, um, I mean, fear is what stops us from doing pretty much anything in our life. Uh, I would say that would be one of them that would be. Uh, but you know, fear does stop us from killing ourselves a lot of times from doing something stupid. So if you took away all fear, then everyone would be fearless and we would be dead. So that would probably not be the best one. So how about this? I'll go with something simple. If we could eliminate sleep problems, that would be the ultimate, I think because we have to do that every day. And if we could always just go to bed and wake up and feel refreshed every morning, I think that that would solve a lot of problems. It's all around the world. Nobody's ever said that and you know, it's so true because I feel like. Most of us are so sleep deprived. And I think that irritability out there, the loss of patience, the lack of kindness, the ability to focus, productivity, parenting. Yeah. Yeah. Your whole mental state and your positivity. It affects all of that. And what else do you spend doing a third of year? You know what I mean? Like that's, it's, it's a tremendous part of your life and nobody focuses on it at all. Um, and yeah.  I agree with you. That is one of the best answers I've ever gotten. So thank you for that. Okay. Vitality feed listeners. I hope everyone got some notes and I will put all the details in the show notes because this one had some, a little more technical information in there. Uh, but this was really fascinating and so informative. Thank you for sharing what you do and for your ability to help people and improve their lives. This was so awesome. I just want to remind our listeners that life has no remote. Get up and change it yourself.  

The ISSCR Recommends New Embryonic Stem Cell Research Guidelines

In this episode, we talk to our stem cell experts Kristina Runeberg and Catharina Brandsten about the use of clinical-grade human embryonic stem cells (hESCs) as starting material for cell therapy. Tune in to learn about some of the advantages of hESCs over other stem cell types and important points to consider when picking a line for cell therapy applications.

We’d love to hear from you (feedback@breakingbadscience.com)Look us up on social media Facebook: https://www.facebook.com/groups/385282925919540Instagram: https://www.instagram.com/breakingbadsciencepodcast/Website: http://www.breakingbadscience.com/Patreon: https://www.patreon.com/breakingbadscienceStem cells are a mysterious cellular construct with some pretty unique properties. Properties which have led to intense discussions about life, aging, cancer, the nature of disease itself, and even religion.  But what are they? Why was the discovery of these cells so important? Why are they so controversial and how has that controversy affected research in the last few decades? Join hosts Shanti and Danny as we discuss stem cells, the confusion surrounding them, and why the controversy is not only important but necessary in this episode of Breaking Bad Science. ReferencesPlatt, A.; A Brief History of U.S. Stem Cell Policy. Research America. 2020. https://www.researchamerica.org/advocacy-action/issues-researchamerica-advocates/stem-cell-research/brief-history-us-stem-cellHwang, N., et. al.; Controlled Differentiation of Stem Cells. Advanced Drug Delivery Reviews. 11-Oct-2007. 60:2 (199 - 214). Doi: https://doi.org/10.1016/j.addr.2007.08.036Robinton, D., Daley, G.; The Promise of Induced Pluripotent Stem Cells in Research and Therapy. Nature. 18-Jan-2012. 481 (295 - 305). Doi: https://doi.org/10.1038/nature10761Chin, M., et. al.; Induced Pluripotent Stem Cells and Embryonic Stem Cells are Distinguished by Gene Expression Signatures. Cell - Stem Cell. 2-Jul-2009. 5:1 (111 - 123). Doi: https://doi.org/10.1016/j.stem.2009.06.008Biehl, J., Russell, B.; Introduction to Stem Cell Therapy. Journal of Cardiovascular Nursing. Mar/Apr-2009. 24:2 (98 - 105). Doi: https://doi.org/10.1097/JCN.0b013e318197a6a5Ayala, F.; Cloning Humans? Biological, Ethical, and Social Considerations. PNAS. 21-Jul-2015. 112:29 (8879 - 8886). Doi: https://doi.org/10.1073/pnas.1501798112Hernandez, D.; 500 Years Later, da Vinci’s Mechanical Lion is Brought to Life. Popular Mechanic. 19-Sep-2019. https://www.popularmechanics.com/technology/a29020685/leonardo-da-vinci-mechanical-lion-display/Ayob, A., Ramasamy, T.; Cancer Stem Cells as Key Drivers of Tumour Progression. Journal of Biomedical Science. 06-Mar-2018. 25:20. Doi: https://doi.org/10.1186/s12929-018-0426-4Kim, K.S.; Converting Human Skin Cells to Neurons: A New Tool to Study and Treat Brain Disorders? Cell - Stem Cell. 2-Sep-2011. 9:3 (179 - 181). Doi: https://doi.org/10.1016/j.stem.2011.08.004Support the show (https://www.patreon.com/breakingbadscience?fan_landing=true)

Will the Covid 19 vaccine contain embryonic stem cells?

Cormac and Saoirse chat to Marcela Iglesias about her $6000 treatment which uses embryonic stem cells to try and prevent aging. See acast.com/privacy for privacy and opt-out information.

Will the Covid 19 vaccine contain embryonic stem cells?

This week the Crawford Broadcasting Roundtable discusses the false claims by the media that President Trump's COVID-19 treatments of Regeneron were created by aborted fetus cells.  What is the truth behind the rumor that  the Regeneron drug given to the President to treat his COVID-19 was made from aborted fetus cells?  What are some of the ethical issues with embryonic stem cell research.  How can we know which vaccine's may involve fetal cells?

Top news, current events and politics, Say What You Will Radio Live Stream - The John Smith Show Greyfeather Farm https://www.etsy.com/shop/GreyfeatherFarm?coupon=SMITH Check out Good Talk Radio http://www.goodtalkradio.com Need a Logo? Tee-shirts? http://www.hardiewear.com Get your CCW or tactical shooting classes: http://www.fastconceptsllc.com --- Send in a voice message: https://anchor.fm/johnsmithshow/message Support this podcast: https://anchor.fm/johnsmithshow/support

Mark Tuszynski MD, PhD UC San Diego Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36353]

Mark Tuszynski MD, PhD UC San Diego Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36353]

Mark Tuszynski MD, PhD UC San Diego Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36353]

Mark Tuszynski MD, PhD UC San Diego Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36353]

Mark Tuszynski MD, PhD UC San Diego Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36353]

Mark Tuszynski MD, PhD UC San Diego Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36353]

Mark Tuszynski MD, PhD UC San Diego Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36353]

Mark Tuszynski MD, PhD UC San Diego Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36353]

In this episode of Life Matters Commissioner Johnston examines the issue of embryonic stem-cell research and California’s upcoming ballot measure Proposition 14. The California Institute for Regenerative Medicine (CIRM) was established in 2004 with the help of more than $6 billion (after interest) by California taxpayers through then Ballot Proposition 71. CIRM has now run out of money. It has spent billions of dollars. Though it had promised miraculous cured through the use of embryonic stem-cell research, each and every experiment was a failure. But they weren’t just failures in the sense of ‘not successful.’ These ethically-questionable medical experiments created tumors, growths and other serious medical problems. In this episode, Brian examines the ethical aspect in addition to the medical, scientifically demonstrated problems of embryonic stem-cell research. Brian goes into depth regarding the facts of the new Proposition 14 which is seeking 5.5 billion dollars more.  

- ROBIN BERTRAM: Hidden Treasures: Finding Hope at the End of Life's Journey - A REMINDER THAT EMBRYONIC STEM CELLS DO NOT CURE ANYTHING! - DR. TIM CLINTON: "Keys to Regaining Emotional and Spiritual Balance in a Post-Pandemic World""Keys to Regaining Emotional and Spiritual Balance in a Post-Pandemic World" - The Centers for Disease Control are Reporting a Dramatic DROP in the Number of Deaths Related EXCLUSIVELY TO COVID 19. Here's How We Can Use this New Data to HELP People Who are Concerned About the Pandemic

The drive to design a COVID-19 vaccine calls attention to the moral concerns about vaccine research using embryonic stem cells, which destroy a human life in the embryonic stage of development. We share two stories about Pluristem Therapeutics, an Israeli biotech company working to produce a vaccine using placental cells, an ethical alternative to embryonic stem cells. We study Power Point slides #25 What Does Rabbi Bleich Say?, and #76 The Use of Language Medical Research. We close the episode with the meditation for today's Omer count. Aired 4/15/20. Preliminary Data from Pluristem's PLC Cell Program Shows Promise in COVID-19 https://www.biospace.com/article/preliminary-data-from-pluristem-s-plc-cell-program-is-promising-in-covid-19/ Stem cells from a baby's placenta may save life of coronavirus victim in NJ. https://nypost.com/2020/04/13/could-stem-cells-from-a-babys-placenta-treat-covid-19/#content-wrapper Moral Implications of Human Fetal Cell Lines in Vaccine Production.  https://thevaccinereaction.org/2019/10/moral-implications-of-human-fetal-cell-lines-in-vaccine-production/ Counting the Nightly Omer https://learnemunah.com/holidays/omercount.html. For Info, Help & Healing please visit jewishprolifefoundation.org

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.08.192591v1?rss=1 Authors: Adolfo Lopez-Ornelas, Itzel Escobedo-Avila, Gabriel Ramirez-Garcia, Rolando Lara-Rodarte, Cesar Melendez-Ramirez, Beetsi Urrieta-Chavez, Tonatiuh Barrios-Garcia, Veronica Caceres-Chavez, Xochitl Flores-Ponce, Francia Carmona, Carlos A Reynoso, Carlos Aguilar, Nora E Kerik, Luisa Rocha, Leticia Verdugo-Diaz, Victor Trevino, Jose Bargas, Veronica Ramos-Mejia, Juan Fernandez-Ruiz, Aurelio Campos-Romo, Ivan Velasco Abstract: Human embryonic stem cells (hESCs) differentiate into specialized cells, including midbrain dopaminergic neurons (DAN). Non-human primates (NHPs) injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine develop some alterations observed in Parkinson disease (PD) patients. We obtained DAN from hESCs and confirmed that they express dopaminergic markers, generate action potentials, and release dopamine (DA) in vitro. DAN were transplanted bilaterally in the putamen of parkinsonian NHPs. After grafting, animals improved motor behavior, evaluated by the HALLWAY task, and in agreement with this recovery, DA release was detected by microdialysis. Imaging techniques revealed changes in fractional anisotropy and mean diffusivity in magnetic resonance imaging and higher 11C-DTBZ binding in positron-emission tomography scans, associated with grafts. Postmortem analysis showed that transplanted DAN survived over ten months in the putamen, without developing tumors, in the immunosuppressed NHPs. These results indicate that cell replacement therapy with hESCs-derived DAN causes long-term biochemical, anatomical, and physiological improvements in this model of PD.Competing Interest StatementThe authors have declared no competing interest. Copy rights belong to original authors. Visit the link for more info

Dry AMD research was a hot topic at this year's ARVO annual meeting. Could ethically sourced stem cells from human embryos provide a solution to this challenging disease? Chris Riemann, MD, shared data from an early phase trial that sought to understand the safety of RPE cells surgically implanted below the retina.

Dry AMD research was a hot topic at this year's ARVO annual meeting. Could ethically sourced stem cells from human embryos provide a solution to this challenging disease? Chris Riemann, MD, shared data from an early phase trial that sought to understand the safety of RPE cells surgically implanted below the retina.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.13.094110v1?rss=1 Authors: Griffin, S. M., Pickard, M. R., Hawkins, C. P., Williams, A. C., Fricker, R. A. Abstract: Emerging evidence indicates that a strong relationship exists between brain regenerative therapies and nutrition. Early life nutrition plays an important role during embryonic brain development, and there are clear consequences to an imbalance in nutritional factors on both the production and survival of mature neuronal populations and the infant's risk of diseases in later life. Our research and that of others suggest that vitamins play a fundamental role in the formation of neurons and their survival. There is a growing body of evidence that nicotinamide, the water-soluble amide form of vitamin B3, is implicated in the conversion of pluripotent stem cells to clinically relevant cells for regenerative therapies. This study investigated the ability of nicotinamide to promote the development of mature catecholaminergic neuronal populations (associated with Parkinson's disease) from mouse embryonic stem cells, as well as investigating the underlying mechanisms of nicotinamide's action. Nicotinamide selectively enhanced the production of tyrosine hydroxylase-expressing neurons and serotonergic neurons from mouse embryonic stem cell cultures (Sox1GFP knock-in 46C cell line). A 5-Ethynyl-2'-deoxyuridine (EdU) assay ascertained that nicotinamide, when added in the initial phase, reduced cell proliferation. Nicotinamide drove tyrosine hydroxylase-expressing neuron differentiation as effectively as an established cocktail of signalling factors, reducing the proliferation of neural progenitors and accelerating neuronal maturation, neurite outgrowth and neurotransmitter expression. These novel findings show that nicotinamide enhanced and enriched catecholaminergic differentiation and inhibited cell proliferation by directing cell cycle arrest in mouse embryonic stem cell cultures, thus driving a critical neural proliferation-to-differentiation switch from neural progenitors to neurons. Further research into the role of vitamin metabolites in embryogenesis will significantly advance cell-based regenerative medicine, and help realize their role as crucial developmental signalling molecules in brain development. Copy rights belong to original authors. Visit the link for more info

Mike West is a legend in the field of Gerontology, the study of aging. Back in the 90's, Mike's company Geron Corp, was the first company to not only successfully isolate embryonic stem cells, but to also isolate the telomerase gene, also known as the immortalizing gene. Gerons discoveries were so significant they prompted the former President of the United States to address the nation. It was an absolute honor to speak with Mike West, who is currently the CEO of Age X Therapeutics. The conversation, initially planned for only 30 minutes, flew by as it turned into an hour and a half long, mind blowing conversation about pluripotent stem cells, telomerase, and the absolute sci fi levels of potential behind these technologies. Arnold Schwarzenegger babies, glowing dogs, a 600 year human life span, and growing replacement organs in a petri dish are just a few of the topics we discussed on today's episode. Strap in, because this conversation is going to take you into orbit. -James Ruhle, SimpleBioTechPodcast.com Stay up to date with the latest episodes and BioTech updates by following me on instagram @SimpleBioTech If you want to know which BioTech companies I'm currently excited about, connect with me on Angel List at Angel.co/jamesruhle

On today’s show, John explains how embryonic stem cell research functions, why it is so unethical, and why it has not been successful in developing treatments and cures. He also discusses the despicable attempt to insert abortion funding into the coronavirus relief package being debated in Congress.

Luke McCoy gives Conduit News his take on Embryonic Stem Cell Research.