Podcast appearances and mentions of David Sinclair

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Play Episode Listen Later Jun 11, 2026 66:11

At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives while supporting medical research into breakthroughs to improve all lives. We're building the world's largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks. __________________________________________ In this first episode of Lifespan Season 2, Dr. David Sinclair, A.O., Ph.D. - Professor of Genetics at Harvard Medical School and pioneer in longevity research - returns and explores one of the most consequential questions in science: How can aging be slowed or reversed? Drawing on more than 25 years of research at the forefront of aging biology, Dr. Sinclair explains why humanity has entered a revolutionary period. Advances in science and technology have converged and transformed aging into a promising target for intervention. This episode is a sweeping introduction to the science, breakthroughs, and emerging technologies that are fundamentally reshaping how we think about aging, disease, and the future of human health. __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in science and that our team has personally used for years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode - from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat and muscle mass (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan or with code LIFESPAN ○ WHOOP: Get a free WHOOP band and one month of membership at https://join.whoop.com/LIFESPAN or with code LIFESPAN ○ Withings: Get 10% off smart health devices at https://withings.com/lifespan or with code LIFESPAN __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship. Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research. The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

Radio Show / Podcast – June 7, 2026

Vital Health Download

Play Episode Listen Later Jun 9, 2026 59:46

Hosts: Ed Jones (Owner – Nutrition World) & Clint Powell A variety of topics for living a healthy life Presented by: Nutrition World www.nutritionw.com Broadcasting from the Nooga Dentistry Studio www.noogadentistry.com Production of: Whitfield Media Group www.vitalhealthradio.com Title: Digestive Enzymes, Gut Health, and Omega-3's with Guest Brenda Watson [0:00:00] Show Intro, National Club Foot Day & Prior Episode Reference Ed mentions National Club Foot Day (previous Wednesday). References a prior Vital Health Radio episode where he strongly criticized a local Chattanooga physician for poor club foot care that nearly harmed his grandson. Ed urges: Anyone with a child/grandchild with club foot seeing providers in Chattanooga listen to our Feb 15th (2026) episode Contact: NutritionWorld@comcast.net to get details of that show and the physician referenced. Emphasis on truth, empowerment, and avoiding harm from medical “inefficiency and ignorance.” [0:03:58] Delta-8 Gummies, Anxiety/Sleep & Lifespan Extension Concepts Recap of a recent show with Hemp House. Ed explains: Only about three weeks left to legally purchase Delta-8 gummies at Hemp House or Nutrition World. Why someone might use Delta-8: Anxiety Trouble sleeping Need to stay functional but calmer Must find the right dose individually (no standard dosing). Safer than many anti-anxiety drugs when used properly. He is saving several containers in his freezer for future “bumps in the road” (periods of poor sleep or high stress). Notes dogs may benefit for anxiety, thunder phobia, pain, etc., when used correctly and from a trusted company. Ed recommends Dr. David Sinclair's “Lifespan” podcast: Focus on practical drugs, supplements, and lifestyle strategies to extend lifespan. Central concept: cellular repair – if we repaired cells at 50 as well as at 20, lifespan could drastically increase. Key tools Dr. Sinclair highlights (as relayed by Ed): Rapamycin – Ed takes this drug himself; impacts mTOR; can extend lifespan even when started later in life. AMPK activators – sold at Nutrition World; support clearing out old/dysfunctional cells. Resveratrol – mimics some effects of fasting. Hyperbaric oxygen – discussed as a potential lifespan extender. Ed shares Sinclair's animal-longevity illustrations: A mole rat living ~20x longer than regular rats → proves there are mechanisms of extended lifespan. A long-lived whale (Clint jokes and riffs on the name) said to reach ~200 years, suggesting humans might mimic similar mechanisms. [0:08:46] Call for Listener Stories & Introduction of Guest Brenda Watson Ed invites listeners to share personal health recovery stories, especially involving “the Green Pharmacy” (natural, nutritional, and lifestyle approaches, including Nutrition World support). Announced collaboration with Clint Powell on a new podcast: Short, credible motivational/educational stories (5–20 minutes). Focus: “I was in bad shape, now I'm much better” recovery narratives. Participants receive a $50 Nutrition World gift card. Recordings at a studio ~5 minutes from Nutrition World. Introduction of guest Brenda Watson, founder of Vital Planet. Described as a guru of gut health and the microbiome: Leaky gut, SIBO, broad digestive health expertise. Ed recalls her long-running NPR fund-raiser specials on gut health that reached tens of thousands. [0:13:25] Digestive Enzymes, Gut Health & Problems with Acid Blockers Topic: What is an enzyme? Why does it matter? Brenda's explanation: Enzymes “break things apart”: Protease → breaks proteins into amino acids. Amylase → breaks starches into glucose. Lipase → breaks fats into fatty acids. Ideally, stomach, pancreas, liver, and gallbladder work together to digest food into absorbable units. Early digestive symptoms: Heartburn, gas, bloating, etc. Many people self-treat with OTC antacids or proton pump inhibitors (PPIs) and this often worsens underlying issues. Her main point: For early digestive symptoms, start with a full-spectrum digestive enzyme (protease, amylase, lipase) with meals, not acid-blocking drugs. As we age, natural digestion weakens, compounded by poor food quality. If food is not properly digested: It rots in the gut → gas, overgrowth of “bad bugs”. Contributes to SIBO, leaky gut, and broader dysbiosis. Leads to poor absorption of nutrients and worsening health. Enzymes as Step One: Should be a first-line intervention alongside or even before probiotics. Emphasizes that digestive enzymes for digestion must be taken with meals. Brenda notes she ran a stool test program with 12 people; often saw imbalanced gut bacteria driven by undigested food. Modern enzyme formulations can be more targeted: Gluten-support enzymes. General high-potency formulas. Formulas for dairy and fat, especially for people on keto who need extra fat-digesting support. She reiterates: Poor digestion = bad bacteria, leaky gut, SIBO, multiple gut issues. Digestive enzymes are a “no-brainer” first step when digestive symptoms appear. [0:23:47] Enzymes as a Foundational Strategy & Aging, Pancreas/Bile Physiology Emphasizes: Rotting food analogy: leftover food in a trash can on a 97°F day = what undigested food can be like inside the gut. Even without symptoms, after age ~40–45, enzymes may be wise especially for people who: Overeat Eat a lot of dairy or gluten Notes loose stools and general poor health can be caused by lack of pancreatic enzymes. Shares a case where a client's stool test showed zero pancreatic enzyme production, correlating with constant sickness. You can “get away with” some other health issues, but you cannot have a dysfunctional digestive tract and still expect even average health. Brenda further explains physiology and pH: Stomach should be very acidic (pH ~2) during digestion. When partly digested food moves into the small intestine: Bicarbonate is released to neutralize acid. Pancreas releases enzymes (protease, amylase, lipase). Liver/gallbladder release bile for fat digestion near the same region. If stomach acid is suppressed, the chain reaction is disrupted: Poor enzyme activation. Poor bile function. pH shifts can foster candida and other imbalances (e.g., colon getting too alkaline). She underscores: From mouth to colon, each region needs appropriate pH. Chronic use of acid blockers has long-term downstream consequences. Ed mentions a simple at-home baking soda test to roughly gauge stomach acid (baking soda in water between meals, watching for burping). Important caution: If you're on acid-blocking medications, you must wean off slowly; do not stop abruptly. Nutrition World's pharmacist, Dr. Curt Dearing, helps people step down from PPIs and H2 blockers safely (in partnership with their physicians). [0:30:58] Omega-3s , Purity, and Heart/Brain Health Ed highlights Vital Omega (Vital Planet): #1 selling product at Nutrition World. Exceptional purity and transparency (heavy emphasis on contaminant-free sourcing). Very high potency (2350 mg of EPA/DHA per serving). No “fish burp” complaints and virtually no returns. Contains lipase enzyme to support fat digestion and further reduce digestive discomfort. Omega blood tests on customers show high omega-3 levels when using this brand. Brenda agrees: Omega-3s are critical at any age, especially in today's toxic environment. You might skip a multivitamin, but you should not skip omega-3s. Ed's additional points: Olive oil and flax oil are not the same as concentrated EPA/DHA. EPA/DHA are essential for cell membranes, cardiovascular health, and cognitive function. Warns of contaminated fish oil from polluted waters (mercury, heavy metals, etc.). Website plug for Vital Planet: VitalPlanet.com for education, and product details. Ed reiterates his respect for Brenda's decades of ethical, passionate work and says they'll have her back on again. [0:38:54] Lifestyle, Local Food, Pillows, and Environmental Toxins Ed and Clint return; Ed summarizes the show's philosophy: Better aging is about strength, clarity, mobility, energy, not just added years. Introduces term “peak span”, maximizing the years we're at peak function, not just lifespan. Critiques normalization of poor health (hunched posture, chronic pain, poor sleep, anxiety) as “just getting old.” Local food talk: Discussion of Tallow House in Cleveland (burger restaurant, cousin of Tony from Portofino). Two-hour waits, excellent reviews, smash burgers, buns from Neidlovs bakery. Dust mites and pillows: Ed cites data that about 1/3 of a pillow can be dead skin + dust mites over time. Many pillows also contain fire retardant chemicals leading to chronic exposure while sleeping. Ed searched for non-toxic pillows via Mamavation: A site that tests products for chemical residues and rates them. His previous pillow (from Avocado) came out top-rated, so he bought a new Avocado pillow. Recommends buying via Mammovation's affiliate link for a small discount. [0:44:00] Essential Oils, Green Pharmacy & Polypharmacy Ed on essential oils quality: A test of 20 lavender oils from Amazon found: Only 3 were pure. 17 were diluted/contaminated with other oils. Smell alone isn't a reliable indicator of quality. Nutrition World only carries brands with Certificates of Analysis; dropped an entire line a few years back over quality concerns. Ed shares a Taiwanese blood pressure study: 58 adults with high blood pressure, many on meds. wore a face mask with a cotton pad containing small amounts of real lavender oil for 15 minutes/day over 7 days. Result: systolic blood pressure reduced by ~10 points. A placebo (fake) oil did not reduce blood pressure. One-day use showed no benefit – consistent use was required. He frames this as an example of the “Green Pharmacy”: Mentions Dr. Curt Dearing (pharmacist at Nutrition World): Helps people review and rationalize medication lists, with the goal of reducing polypharmacy in collaboration with prescribing doctors. References a recent Vital Health Radio episode on polypharmacy (average American takes ~17 prescriptions per year). [0:56:48] Meditation, Mindset, Ancient Wisdom & Fulfillment Story from the Daily Stoic: Kurt Vonnegut and Joseph Heller at a billionaire's party: Vonnegut points out the host made more money yesterday than Heller's Catch-22 ever did. Heller replies he has something the billionaire never will: “the knowledge that I've got enough.” Ed uses this to emphasize: The power of knowing you have enough. Shifting from chasing money to working for fulfillment once basics are covered. Clint adds: You must learn to be content with what you have while still pursuing goals. More stuff doesn't automatically create a content person. Ed reads a longer reflection on “ancient wisdom” vs. modern medicine: Fundamental philosophy: alignment with nature. Humans thrived for millennia without pharmaceuticals (acknowledges infectious disease issues before hygiene and antibiotics). Nearly every drug has unintended consequences and rarely treats root causes. Cites estimate: medical errors as the 3rd leading cause of death in the US (~250,000 deaths/year). Notes ~90% of American calories now come from processed foods and seed oils Argues seed oils are among the most destructive components of the modern diet. Many cardiologists still recommend them as heart-healthy, highlighting the conflict between mainstream and holistic views. Plug for Ed's book: “Are You Sick and Tired of Being Sick and Tired” available at TheHolisticNavigator.com, built around ancient wisdom. The post Radio Show / Podcast – June 7, 2026 first appeared on Vital Health Radio.

Godlike AI Is Here! Peter Diamandis Debates Brian Keating

Into the Impossible

Play Episode Listen Later Jun 1, 2026 60:02

Peter Diamandis has built more of the future than almost anyone alive. He founded XPRIZE. He co-founded Singularity University with Ray Kurzweil. He started Human Longevity with Craig Venter. And in his new book with Steven Kotler, We Are as Gods, he argues that artificial intelligence isn't just changing what we can do. It's changing what it means to be human. I'm not so sure. This is Peter's fifth time on Into the Impossible, and the conversation I've been waiting years to have. His thesis: AI will deliver not just intelligence at scale, but wisdom — and humanity is already crossing the threshold into godlike capability, whether we're ready or not. My pushback: an experiment one of my students and I ran shows large language models trained only on pre-1911 physics cannot reproduce what Einstein did with the same data. If wisdom were just scale, that shouldn't be true. We go after it for an hour. No hedging, no softening. What you'll hear: — Whether AGI can manufacture genuine wisdom or just better simulations of it — The pre-1911 Einstein test and what it reveals about the ceiling of current AI — The "five forks of humanity": longevity, BCI, off-planet speciation, creators vs. consumers, and uploading — What happens to human purpose when scarcity disappears — Why Peter thinks India dominates the next twenty years of science and technology — Peter's Fermi paradox theory and why he thinks we may be someone else's biosphere experiment — The Future Vision XPRIZE and how dystopian training data may be making AI more dangerous — David Sinclair's epigenetic age-reversal trials, now underway in human eyes Peter says what you did between breakfast and dinner would be godlike to your grandparents. We just stopped noticing. Subscribe if you want science with evidence, not speculation. CHAPTERS 00:00 Diamandis: AGI will generate wisdom by simulating billions of outcomes 04:07 Brian's counterargument: wisdom requires embodiment, not just simulation 07:07 The GPU + LLM architecture may already be a local maximum 09:48 AI is outpacing most math PhDs but the ceiling is still unknown 15:30 Diamandis fires back at the doomers 17:59 AI will eventually untangle the legal systems blocking the future 23:18 The Singularity has religious qualities and both hosts take that seriously 29:37 Post-scarcity splits humanity into creators and consumers 36:08 Peter's Fermi paradox theory: we may be someone else's biosphere experiment 43:07 Dystopian AI training data may be causing misalignment 51:46 Human trials are underway for epigenetic eye age reversal ——— Get the transcript, fascinating bonus content, and my Monday M.A.G.I.C. Message: https://briankeating.com/yt Have a .edu email and live in the USA? You automatically win a meteorite: https://BrianKeating.com/edu Subscribe: https://www.youtube.com/DrBrianKeating?sub_confirmation=1 Support Into the Impossible on Patreon — get my weekly M.A.G.I.C. Message, unfiltered bonus content, and live monthly Office Hours with me: https://www.patreon.com/drbriankeating Join this channel for perks, monthly Office Hours, and your name in the Member Roster at the end of every episode: https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join My books: Losing the Nobel Prize (memoir): http://amzn.to/2sa5UpA Think Like a Nobel Prize Winner: https://a.co/d/03ezQFu Focus Like a Nobel Prize Winner: https://a.co/d/hi50U9U Galileo's Dialogue (first-ever audiobook): https://a.co/d/iZPi9Un More: Peter Diamandis Moonshots Podcast: https://www.diamandis.com/podcast Peter Diamandis Substack: https://metatrends.substack.com/ Future Vision XPRIZE: https://futurevisionxprize.com/ Book We Are as Gods: https://a.co/d/0bfz2pBo Peter Diamandis YouTube: https://www.youtube.com/@peterdiamandis Follow Peter on X: https://x.com/PeterDiamandis Twitter/X: https://x.com/BrianKeating Substack: https://briankeating.substack.com Blog: https://briankeating.com/blog Audio-only: https://briankeating.com/podcast #intotheimpossible #briankeating #science #physics #astronomy #cosmology #podcast #universe #peterdiamandis #ai #agi #singularity #abundance #longevity Learn more about your ad choices. Visit megaphone.fm/adchoices

UnDisciplined: How athletes change their perception of time

UnDisciplined

Play Episode Listen Later May 28, 2026 25:56

A few years back, we had David Sinclair on the program. David is one of the world's top researchers working on the question of whether we can extend human lifespans.A couple years after that, Nate Price was with us. Nate is also looking at this question, though from a different angle: he wants to know how we can pack more healthy years into the lifespans we already have.But here on the program, we find ourselves returning to another version of that same question: what does it actually mean to lengthen a life?Brett Popplewell has been thinking about that too — about whether a life can feel longer not only through years added, but through attention, novelty, memory, movement, and the refusal to let the days become interchangeable.

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Dr David Sinclair: What if Aging Isn't Inevitable, But Something We Can Actually Slow Down or Reverse?

A Life of Greatness

Play Episode Listen Later May 25, 2026 70:27

In this groundbreaking conversation, Professor of Genetics and longevity scientist, Dr. David Sinclair, A.O., Ph.D., joins Sarah Grynberg to unpack the future of human aging, the science oflongevity, and how we live today impacts how we age tomorrow.From reversing blindness in mice to exploring treatments that could one day delay menopause and extend healthy human life, this episode will completely change the way you think about your body, your health, and your future.But beyond the science, this is also a deeply human conversation about purpose, suffering, love, family, and what it truly means to live a great life.In this episode, you will learn:Why aging may actually be reversibleThe daily habits accelerating aging in your body right nowHow stress, loneliness, and cortisol could impact longevityThe real science behind supplements like NMN, resveratrol, and NAD boostersWhy exercise, sleep, and relationships matter more than you thinkWhat Dr. Sinclair believes is coming in the next 10 years of medicineHow scientists are working to reverse female infertility and delay menopauseThe surprising reason your “biological age” may be younger or older than your real ageWhy suffering through disease and decline should not be considered “normal aging”The philosophy and mindset Dr. Sinclair lives by every dayThis episode is a powerful reminder that longevity is not just about living longer… it's about living better.To find out more about Dr Sinclair's work:Website: lifespan.com and friendsofsinclairlab.orgBook: Lifespan: Why We Age—and Why We Don't Have ToPodcast: Lifespan with Dr. David Sinclair on Spotify, Apple, YouTubePurchase Sarah's book: Living A Life Of Greatness here.To purchase Living A Life of Greatness outside Australia here or here.Watch A Life of Greatness Episodes On Youtube here.Sign up for Sarah's newsletter (Greatness Guide) here.Purchase Sarah's Meditations here.Instagram: @sarahgrynberg Website: https://sarahgrynberg.com/Facebook: facebook.com/sarahgrynbergTwitter: twitter.com/sarahgrynberg Hosted on Acast. See acast.com/privacy for more information.

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Can Science Slow Aging? | David Donnelly

Live Long and Master Aging

Play Episode Listen Later May 22, 2026 50:19 Transcription Available

For decades, aging was seen as inevitable — a slow and irreversible decline. But a growing number of scientists now believe we may be entering a turning point, with research increasingly focused on extending not just how long we live, but how well we live.In the documentary Forever Young, filmmaker David Donnelly — alongside producers Dr. James Johnson and Dr. Thomas Lewis — explores the rapidly evolving world of longevity science, from biological clocks and AI-driven research to the power of lifestyle, purpose, and social connection.The film also confronts some of the field's biggest questions: what aging actually is, whether it should be treated as a disease, and who stands to benefit if the science succeeds. In this conversation with Peter Bowes, Donnelly reflects on skepticism, scientific disagreement, and why he believes humanity may already be living through a longevity revolution.--Learn more about Forever Young: The end of aging has just begunApple TV Pre-order | Official Website | Substack | Instagram | X | Facebook | YouTube | Watch the Trailer--DISCLOSURE: This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts SpotifyEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountPartiQlar supplementsEnhance your wellness journey with pure single ingredients. 15% DISCOUNT - use code: MASTERAGING15Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

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Can we reverse aging and cure dry eye disease?

The Eye Show

Play Episode Listen Later May 22, 2026 9:50

In this episode of The Eye Show, Dr. Sandra Cremers discusses groundbreaking research from Dr. David Sinclair on epigenetics, longevity, and reducing “Inflammaging” — the chronic inflammation linked to aging and disease.From ocular surface health to the science of aging, this conversation explores what the future of medicine may hold for dry eye treatment and beyond.

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The Most Surprising Longevity Discoveries | Lifespan with Dr. David Sinclair Rewind

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Play Episode Listen Later May 21, 2026 76:10

What are the most important things you can do today to live longer and stay healthier while doing it? In this final Lifespan Rewind episode, Dr. David Sinclair, A.O., Ph.D., a Professor of Genetics for over 25 years at Harvard Medical School and a leader in the field of longevity research, revisits the most surprising insights from his #1-ranked Season 1 series, combining updated commentary with key moments from across all eight episodes. The result is a thought-provoking, focused, practical guide to the science of longevity – grounded in evidence and designed for real-world application. Whether you're new to longevity science or looking to refine your approach, this episode brings together the most important principles in one place so you can better understand not just what to do, but why it matters. At Lifespan, our mission is to help you and your loved ones live longer, healthier lives while supporting medical research aimed at breakthroughs to extend all our lives. Join us at: https://lifespan.com. We're building the world's largest longevity community who will grow, learn, and live longer together. Subscribe here for new Lifespan show episodes every two weeks. __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in strong science – and products our team has personally used for many years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode – from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat content and muscle gains (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan with code LIFESPAN ○. WHOOP: Get a free WHOOP band plus one month free at https://join.whoop.com/LIFESPAN with code LIFESPAN ○. Withings: Explore their smart health devices at https://withings.com/lifespan using code LIFESPAN __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship. Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research. The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

David Sinclair Interview, Cocodona Viewership Stats, & the State of Trail Race Live Streaming

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Play Episode Listen Later May 20, 2026 78:27

Join us for a special Wednesday edition of Rest Day, today at 1pm PT on the Freetrail YouTube channel. We'll talk to David Sinclair about his amazing course record victory at Transvulcania and his path to Western States. In the back half of the show, we'll be joined by Zac Marion to talk about the state of live-streaming and the amazing 125hr broadcast he led at the Cocodona 250. We'll be LIVE on YouTube starting at 1pm PT today. SUBSCRIBE TO FREETRAIL'S NEWSLETTER - https://mailing.freetrail.com/newslettersignup JOIN FREETRAIL PRO - https://freetrail.com/pro REGISTER FOR TRAILCON - https://trailconference.com/register/ Sponsors: Use code FREETRAIL25 for 25% off your first order of NEVERSECOND nutrition at https://www.never2.com Check out the Capilene Cool Sun Hoodie from Patagonia https://www.patagonia.com/shop/favorites/capilene-cool-tech-tees/sun Use this link for 30% off Ketone-IQ - https://ketone.com/pages/dylan-bowman?utm_source=partners&utm_medium=referral&utm_campaign=FREETRAIL30 Freetrail Links: Website | https://freetrail.com/ Freetrail Pro | https://freetrail.com/freetrail-pro/ Patreon | https://www.patreon.com/dylanbowman Instagram | https://www.instagram.com/runfreetrail/ YouTube | https://www.youtube.com/channel/UC8MKI1xB8YMchI1764zJXHg Freetrail Experts | https://freetrail.com/freetrail-experts/ Dylan Links: Instagram | https://www.instagram.com/dylanbo/ Twitter | https://twitter.com/dylanbo LinkedIn | https://www.linkedin.com/in/dylan-bowman-06174380/ Strava | https://www.strava.com/pros/1596921

Season 2 Official Trailer: Lifespan with Dr. David Sinclair

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Play Episode Listen Later May 18, 2026 1:32

What if aging is more reversible than we once thought? Season 2 of Lifespan with Dr. David Sinclair, A.O., Ph.D., explores the latest breakthroughs in longevity science - from epigenetic restoration to fasting, exercise, sleep, metabolism, and the emerging technologies that could help us live longer and healthier lives. Drawing on more than 30 years of research and conversations at the frontier of science and medicine, Dr. Sinclair breaks down complex discoveries into practical, evidence-based insights designed to help you understand how the body ages - and what may be possible to slow, optimize, or even reverse aspects of that process. This season features: • New episodes on fasting, exercise, metabolic health, and longevity science • The latest research on biological aging and cellular repair • Practical tools for healthier living backed by scientific evidence • New conversations around the future of medicine and human healthspan We're building the world's largest longevity community, focused on supporting medical research and living longer, together. Join us at https://lifespan.com Follow Lifespan: Instagram: https://instagram.com/lifespan X: https://x.com/JoinLifespan Follow Dr. David Sinclair: Instagram: https://instagram.com/davidsinclairphd Threads: https://threads.net/@davidsinclairphd X: https://x.com/davidasinclair Bluesky: https://bsky.app/profile/davidsinclairphd.bsky.social LinkedIn: https://linkedin.com/in/davidsinclairphd YouTube: https://www.youtube.com/@LifespanOfficial Watch or listen on YouTube, Spotify, and Apple Podcasts.

TRANSVULCANIA : POURQUOI LES CHRONOS ONT ÉTÉ FRACASSÉS ?

La Bande Ã D+

Play Episode Listen Later May 14, 2026 128:07

GRAND DEBRIEF avec la championne BLANDINE L'HIRONDEL et trois des meilleurs Français de cette édition 2026 DAMIEN HUMBERT, ROBIN JUILLAGUET et ANTHONY COSTA.Le 90e épisode de La Bande à D+, présenté par Nicolas Fréret de Distances+,est consacré à cette édition exceptionnelle de la Transvulcania aux Canaries… Exceptionnelle parce que l'épreuve phare, l'ultra-marathon de 75 km et 4200 m de dénivelé, remportée par la Française Blandine L'hirondel et l'Américain David Sinclair, a été marquée par des performances historiques en ce début de saison et une ribambelle de chronos canons.Pourquoi les chronos se sont-ils affolés? Écoutez cet épisode pour le découvrir, avec des nombreuses anecdotes de course puisque l'ensemble des chroniqueurs et invités ont participé à la Transvulcania cette année. Damien Humbert a terminé 4e, Robin Juillaguet 8e, et Anthony Costa, médecin cardiologue et traileur élite amateur, 29e.Également au sommaire de ce 10e épisode de la saison 5 du talk-show du trail :

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The 91-Year-Old Physicist Betting His Body on Mitochondrial Transplant | John Cramer PhD

Health Longevity Secrets

Play Episode Listen Later May 12, 2026 58:34 Transcription Available

What if aging isn't a hundred separate problems but a single one — an energy crisis inside the tiny power plants of every cell? At 91, Dr. John G. Cramer is betting his own body on the answer.In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. John G. Cramer — Emeritus Professor of Physics at the University of Washington and author of "How to Live Much Longer" — the oldest human on Earth to receive an experimental mitochondrial transplant. They unpack a unifying theory of aging built around damaged mitochondrial DNA, why replication errors (not just free radicals) drive most of the damage, and what it felt like to receive escalating doses of "Mitlets" — liposomes carrying fresh mitochondria harvested from young blood platelets — at a Texas right-to-try clinic.Buy Dr. Cramer's book "How to Live Much Longer": https://www.amazon.com/How-Live-Much-Longer-Cramer/dp/B0DV3ZW5T6 Cramer & Benson white paper (CBC): https://faculty.washington.edu/jcramer/Bio/CBC.pdf Mitrix Bio: https://mitrix.bio/CHAPTERS00:00 Cold open — "the oldest young human on the planet" 01:18 Meet Dr. John Cramer: physicist turned longevity pioneer at 91 03:45 Why a physicist became obsessed with aging 06:20 The unifying theory: aging as mitochondrial DNA damage 09:40 The 16,569 base pairs that run your life 13:05 Replication errors vs. free radicals — correcting Denham Harman 16:30 The damage doubling time: 12 years, then 3-4 19:50 David Sinclair's information theory of aging 23:15 James McCully and the birth of mitochondrial transplantation 27:00 "No negative results, only spectacular successes" 30:25 Mitrix Bio, Tom Benson, and the Mitlet platform 34:10 Inside Cramer's four Texas right-to-try sessions 38:30 Arm injection, belly fat, and the IV mainline that worked 42:15 What it actually feels like to receive young mitochondria 45:40 Haplogroup H2A1G1 and the Norwegian great-grandmother 48:20 The economics: scaling Mitlets to the world 51:05 Becoming the oldest young human — target age 129 54:30 What Cramer wants you to do tomorrow morning 57:00 Final reflections and where to find the bookKEY STUDIES & SOURCESCramer J.G. & Benson T. — Cellular Bioenergetic Crisis white paper: https://faculty.washington.edu/jcramer/Bio/CBC.pdfHarman D. (1972) — The biologic clock: the mitochondria?: ⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every Tuesday & Thursday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/

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Transvulcania y 101 ronda: Dos magníficas carreras de montaña, por Mayayo.

RADIO TRAIL Carreras de Montaña Mayayo

Play Episode Listen Later May 11, 2026 51:49 Transcription Available

Transvulcania y 101 ronda: Dos magníficas carreras de montaña, por Mayayo. Hoy en RADIO TRAIL MAYAYO toca viaje doble. Volvemos desde dentro a la Transvulcania más rápida jamás vista, con el ambiente eléctrico del Roque de Los Muchachos y las bajadas suicidas hacia Tazacorte, pero también regresamos al barro de Ronda, a los pueblos de la Serranía llenos de legionarios, frontales y corredores exhaustos peleando durante toda la noche. Dos formas distintas de entender el trail running. Una mirando a la élite mundial y otra abrazando el alma popular del ultrafondo español. Y las dos, este fin de semana, absolutamente inolvidables.https://go.ivoox.com/rf/173462178En La Palma vimos probablemente una de las mejores ediciones de Transvulcania de toda su historia. La carrera canaria rompió todos los registros posibles con ocho récords pulverizados entre Kilómetro Vertical, Media, Maratón y Ultramaratón. David Sinclair firmó una exhibición memorable en la Ultra con 6h32:24 mientras Blandine L'Hirondel conquistó la isla batiendo también el récord femenino en 7h43:43. Y no fueron casos aislados: la velocidad de cabeza fue tan brutal que hasta seis hombres bajaron el antiguo récord histórico de la Ultramaratón en una jornada sencillamente irrepetible para el trail mundial.Mientras tanto, en Ronda vivimos exactamente lo contrario… y quizá por eso mismo tan emocionante. Allí no hubo terreno seco ni pistas rápidas para volar. Hubo lluvia, barro, piernas destrozadas y una edición especialmente dura de los 101 de La Legión. Pero incluso así, José Ángel Fernández “Canales” firmó una actuación salvaje para romper el récord histórico con 7h42:46, rebajando la mejor marca previa en más de media hora sobre un terreno muchísimo más lento de lo habitual. Y junto a él, María Romero volvió a demostrar por qué ya es leyenda de esta carrera, ganando otra vez pese a correr lesionada en una edición donde terminar ya era una pequeña victoria personal para miles de populares. Sergio Garasa Mayayo.#carrerasdemontaña #radiotrail Conviértete en un supporter de este podcast: https://www.spreaker.com/podcast/radio-trail-carreras-de-montana-mayayo--4373839/support.

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TRANSVULCANIA Y 101 RONDA: Dos magníficas carreras de montañ, por Mayayo.

RADIO TRAIL CARRERAS DE MONTAÑA, por Mayayo

Play Episode Listen Later May 11, 2026 51:48

TRANSVULCANIA Y 101 RONDA: Dos magníficas carreras de montañ, por Mayayo. Hoy en RADIO TRAIL MAYAYO toca viaje doble: Volvemos desde dentro a la Transvulcania más rápida jamás vista, con el ambiente eléctrico del Roque de Los Muchachos y las bajadas suicidas hacia Tazacorte, pero también regresamos al barro de Ronda, a los pueblos de la Serranía llenos de legionarios, frontales y corredores exhaustos peleando durante toda la noche. Dos formas distintas de entender el trail running. Una mirando a la élite mundial y otra abrazando el alma popular del ultrafondo español. Y las dos, este fin de semana, absolutamente inolvidables. En La Palma vimos probablemente una de las mejores ediciones de Transvulcania de toda su historia. La carrera canaria rompió todos los registros posibles con ocho récords pulverizados entre Kilómetro Vertical, Media, Maratón y Ultramaratón. David Sinclair firmó una exhibición memorable en la Ultra con 6h32:24 mientras Blandine L'Hirondel conquistó la isla batiendo también el récord femenino en 7h43:43. Y no fueron casos aislados: la velocidad de cabeza fue tan brutal que hasta seis hombres bajaron el antiguo récord histórico de la Ultramaratón en una jornada sencillamente irrepetible para el trail mundial. Mientras tanto, en Ronda vivimos exactamente lo contrario… y quizá por eso mismo tan emocionante. Allí no hubo terreno seco ni pistas rápidas para volar. Hubo lluvia, barro, piernas destrozadas y una edición especialmente dura de los 101 de La Legión. Pero incluso así, José Ángel Fernández “Canales” firmó una actuación salvaje para romper el récord histórico con 7h42:46, rebajando la mejor marca previa en más de media hora sobre un terreno muchísimo más lento de lo habitual. Y junto a él, María Romero volvió a demostrar por qué ya es leyenda de esta carrera, ganando otra vez pese a correr lesionada en una edición donde terminar ya era una victoria personal para miles de populares. Sergio Garasa Mayayo #carrerasdemontaña #radiotrail

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What To Do For Longevity | Lifespan with Dr. David Sinclair Rewind

professor legal partners harvard university longevity emerging genetics harvard medical school sinclair whoop lifespan david sinclair withings ketone iq

Play Episode Listen Later May 6, 2026 59:10

What are the most important things you can do today to live longer and stay healthier while doing it? In this first Lifespan Rewind episode, Dr. David Sinclair, A.O., Ph.D., a Professor of Genetics for over 25 years at Harvard Medical School and a leader in the field of longevity research, revisits the most impactful insights from his #1-ranked Season 1 series, combining updated commentary with key moments from across all eight episodes. The result is a focused, practical guide to the science of longevity – grounded in evidence and designed for real-world application. This episode covers: What to eat – and what to avoid – for long-term health How to think about exercise for longevity (not just performance) The role of cold and heat exposure Which supplements may support healthy aging Emerging medical interventions and what the science actually shows The tools and protocols Dr. Sinclair personally uses in his own routine Whether you're new to longevity science or looking to refine your approach, this episode brings together the most important principles in one place so you can better understand not just what to do, but why it matters. At Lifespan, our mission is to help you and your loved ones live longer, healthier lives while supporting medical research aimed at breakthroughs to extend all our lives. Join us at: https://lifespan.com. We're building the world's largest longevity community who will grow, learn, and live longer together. Subscribe here for new Lifespan show episodes every two weeks. __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in strong science – and products our team has personally used for many years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode – from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat content and muscle gains (Withings). If you'd like to learn more or try these tools: Ketone-IQ: Get 30% off your first monthly order at ketone.com/lifespan with code LIFESPAN WHOOP: Get a free WHOOP band plus one month free at join.whoop.com/LIFESPAN with code LIFESPAN Withings: Explore their smart health devices at withings.com/lifespan using code LIFESPAN __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship. Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research. The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

What To Do For Longevity | Lifespan with Dr. David Sinclair Rewind

health professor partners harvard university longevity emerging genetics harvard medical school sinclair whoop lifespan david sinclair withings ketone iq

Play Episode Listen Later May 6, 2026 59:10

What are the most important things you can do today to live longer and stay healthier while doing it? In this first Lifespan Rewind episode, Dr. David Sinclair, A.O., Ph.D., a Professor of Genetics for over 25 years at Harvard Medical School and a leader in the field of longevity research, revisits the most impactful insights from his #1-ranked Season 1 series, combining updated commentary with key moments from across all eight episodes. The result is a focused, practical guide to the science of longevity – grounded in evidence and designed for real-world application. This episode covers: What to eat – and what to avoid – for long-term health How to think about exercise for longevity (not just performance) The role of cold and heat exposure Which supplements may support healthy aging Emerging medical interventions and what the science actually shows The tools and protocols Dr. Sinclair personally uses in his own routine Whether you're new to longevity science or looking to refine your approach, this episode brings together the most important principles in one place so you can better understand not just what to do, but why it matters. At Lifespan, our mission is to help you and your loved ones live longer, healthier lives while supporting medical research aimed at breakthroughs to extend all our lives. Join us at: https://lifespan.com. We're building the world's largest longevity community who will grow, learn, and live longer together. Subscribe here for new Lifespan show episodes every two weeks. __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in strong science – and products our team has personally used for many years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode – from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat content and muscle gains (Withings). If you'd like to learn more or try these tools: Ketone-IQ: Get 30% off your first monthly order at ketone.com/lifespan with code LIFESPAN WHOOP: Get a free WHOOP band plus one month free at join.whoop.com/LIFESPAN with code LIFESPAN Withings: Explore their smart health devices at withings.com/lifespan using code LIFESPAN __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship. Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research. The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

CrossFit's New CEO, Zwift Buys Rouvy, Tally Health Gets Acquired

Fitt Insider

Play Episode Listen Later Apr 30, 2026 2:33

April 30, 2026: Your daily rundown of health and wellness news, in under 5 minutes. Today's top stories: CrossFit appoints Bruce Edwards as CEO, former COO bringing experience from barre3 and Planet Fitness to stabilize brand amid HYROX competition Zwift acquires Rouvy combining gamified training with real-world routes, consolidating cycling stack after raising $600M+ and expanding into hardware Infinite Epigenetics acquires Tally Health co-founded by David Sinclair, creating vertically integrated platform across epigenetic testing and consumer longevity More from Fitt: Fitt Insider breaks down the convergence of fitness, wellness, and healthcare and what it means for business, culture, and capital. Subscribe to our newsletter → insider.fitt.co/subscribe Work with our recruiting firm → talent.fitt.co Follow us on Instagram → instagram.com/fittinsider Follow us on LinkedIn → linkedin.com/company/fittinsider Reach out → insider@fitt.co

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It's Never Too Late to Live Longer | David Sinclair Lifespan

Moonshots - Adventures in Innovation

Play Episode Listen Later Apr 30, 2026 47:39

What if aging isn't a fixed path—but a system you can influence?In this episode of Moonshots, Mike and Mark dive into the groundbreaking ideas of Dr. David Sinclair, author of Lifespan. Through a curated set of powerful clips, they unpack the science and philosophy behind longevity—and, more importantly, what it means for how we live today.Get your copy of Lifespan by David Sinclair here:

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David Sinclair: The GLP-1 Side Effect No One Talks About, What AI Found in His Lab, and Reversing Blindness | Q&A EP #251

Moonshots with Peter Diamandis

Play Episode Listen Later Apr 28, 2026 27:04

This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/ This Q&A is about longevity, and especially how David Sinclair sees AI speeding up drug discovery, biological-age reversal, and the future of healthspan. It also covers GLP-1s, telomeres, genetics, muscle preservation, hormone replacement, indoor environment, and the role of mindset in aging well. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 David A. Sinclair, A.O., Ph.D., is a tenured Professor of Genetics at Harvard Medical School and a serial biotech entrepreneur. Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter _ Connect with Peter: X Instagram Substack Website Xprize Connect with David X Instagram Website Listen to MOONSHOTS: Apple YouTube – *Recorded on March 9th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

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David Sinclair on the Longevity Pill, Age Reversal Timelines, and Updated Protocols | EP #250

Moonshots with Peter Diamandis

Play Episode Listen Later Apr 27, 2026 32:32

This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/ In this insightful interview, Dr. David Sinclair discusses groundbreaking advancements in longevity research, including epigenetic reprogramming trials, the potential for extending human lifespan, and accessible therapies. He shares his personal protocols and the future of anti-aging science, emphasizing the importance of innovation and community support. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends David A. Sinclair, A.O., Ph.D., is a tenured Professor of Genetics at Harvard Medical School and a serial biotech entrepreneur. Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter _ Connect with Peter: X Instagram Connect with David X Instagram Website Listen to MOONSHOTS: Apple YouTube – *Recorded on March 9th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

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We Can Now Drive Aging Forward and Backward at Will — Here's What That Means | Impact Theory W. Tom Bilyeu Dr. David Sinclair

Play Episode Listen Later Apr 18, 2026 82:22

Welcome back to Impact Theory with Tom Bilyeu. In this electrifying continuation, Tom Bilyeu dives deep with world-renowned aging researcher Dr Sinclair to explore the cutting edge of anti-aging science and regenerative medicine. Prepare for a mind-bending journey through lab-grown “mini brains,” the ethics of creating organs from scratch, and the real-world implications of reversing aging—in everything from skin and hair to the human brain and spinal cord. You'll hear insights on the latest advances in using AI to develop longevity drugs, the surprising possibilities for reversing age-related infertility, and how upcoming clinical trials may soon change the way we think about disease, aging, and human potential. Plus, Dr Sinclair shares his personal health protocol and practical strategies for extending your lifespan today, all while tackling big questions about the future—from living to 1000 years, to the cautionary tales and optimism inherent in this rapidly evolving field. Get ready for a conversation that bridges science fiction and reality as Tom Bilyeu and Dr Sinclair unpack what it means to truly disrupt aging. What's up, everybody? It's Tom Bilyeu here: If you want my help... STARTING a business: join me here at ZERO TO FOUNDER: https://tombilyeu.com/zero-to-founder?utm_campaign=Podcast%20Offer&utm_source=podca[%E2%80%A6]d%20end%20of%20show&utm_content=podcast%20ad%20end%20of%20show SCALING a business: see if you qualify here.: https://tombilyeu.com/call Get my battle-tested strategies and insights delivered weekly to your inbox: sign up here.: https://tombilyeu.com/ ********************************************************************** If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu's Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you. ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Blinkist: Start your free trial at https://blinkist.com/impactQuince: Free shipping and 365-day returns at https://quince.com/impactpodIncogni: Take your personal data back with Incogni! Use code IMPACT at the link below and get 60% off an annual plan: https://incogni.com/impactAT&T Business: Switch to AT&T Business at business.att.comNetsuite: Right now, get our free business guide, Demystifying AI, at https://NetSuite.com/TheoryKetone IQ: Visit https://ketone.com/IMPACT for 30% OFF your subscription orderSumm: code TOMVIP20 for 20% off your first year at https://summ.com?via=tombilyeu&coupon=TOMVIP20Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impactCozy Earth: code IMPACT for 20% off https://cozyearth.comQuo: Try for free PLUS get 20% off your first 6 months at https://quo.com/impact micro brains, stem cells, brain organoids, blood vessel cells, pituitary gland, calcium imaging, ethical questions in science, aging models, AI in biology, gene therapy, chemical cocktails, clinical trials, phase one trials, sirtuin activators, NAD IV, fertility reversal, uterus regeneration, brain health supplements, ketones, intermittent fasting, DNA methylation, gene expression, Alzheimer's disease, amyloid plaques, optic nerve regeneration, glaucoma treatment, skincare de-aging, hair regrowth, statins, metformin, anti-cancer nutrition Learn more about your ad choices. Visit megaphone.fm/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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We Can Now Drive Aging Forward and Backward at Will — Here's What That Means | Impact Theory W. Tom Bilyeu Dr. David Sinclair

Play Episode Listen Later Apr 18, 2026 85:52

Welcome back to Impact Theory with Tom Bilyeu. In this electrifying continuation, Tom Bilyeu dives deep with world-renowned aging researcher Dr Sinclair to explore the cutting edge of anti-aging science and regenerative medicine. Prepare for a mind-bending journey through lab-grown “mini brains,” the ethics of creating organs from scratch, and the real-world implications of reversing aging—in everything from skin and hair to the human brain and spinal cord. You'll hear insights on the latest advances in using AI to develop longevity drugs, the surprising possibilities for reversing age-related infertility, and how upcoming clinical trials may soon change the way we think about disease, aging, and human potential. Plus, Dr Sinclair shares his personal health protocol and practical strategies for extending your lifespan today, all while tackling big questions about the future—from living to 1000 years, to the cautionary tales and optimism inherent in this rapidly evolving field. Get ready for a conversation that bridges science fiction and reality as Tom Bilyeu and Dr Sinclair unpack what it means to truly disrupt aging. What's up, everybody? It's Tom Bilyeu here: If you want my help... STARTING a business: join me here at ZERO TO FOUNDER: https://tombilyeu.com/zero-to-founder?utm_campaign=Podcast%20Offer&utm_source=podca[%E2%80%A6]d%20end%20of%20show&utm_content=podcast%20ad%20end%20of%20show SCALING a business: see if you qualify here.: https://tombilyeu.com/call Get my battle-tested strategies and insights delivered weekly to your inbox: sign up here.: https://tombilyeu.com/ ********************************************************************** If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu's Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you. ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Blinkist: Start your free trial at https://blinkist.com/impactQuince: Free shipping and 365-day returns at https://quince.com/impactpodIncogni: Take your personal data back with Incogni! Use code IMPACT at the link below and get 60% off an annual plan: https://incogni.com/impactAT&T Business: Switch to AT&T Business at business.att.comNetsuite: Right now, get our free business guide, Demystifying AI, at https://NetSuite.com/TheoryKetone IQ: Visit https://ketone.com/IMPACT for 30% OFF your subscription orderSumm: code TOMVIP20 for 20% off your first year at https://summ.com?via=tombilyeu&coupon=TOMVIP20Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impactCozy Earth: code IMPACT for 20% off https://cozyearth.comQuo: Try for free PLUS get 20% off your first 6 months at https://quo.com/impact micro brains, stem cells, brain organoids, blood vessel cells, pituitary gland, calcium imaging, ethical questions in science, aging models, AI in biology, gene therapy, chemical cocktails, clinical trials, phase one trials, sirtuin activators, NAD IV, fertility reversal, uterus regeneration, brain health supplements, ketones, intermittent fasting, DNA methylation, gene expression, Alzheimer's disease, amyloid plaques, optic nerve regeneration, glaucoma treatment, skincare de-aging, hair regrowth, statins, metformin, anti-cancer nutrition Learn more about your ad choices. Visit megaphone.fm/adchoices

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AI Just Compressed 160 Years of Aging Research — Here's What They Found | Dr. David Sinclair | Impact Theory w. Tom Bilyeu & David Sinclair

Play Episode Listen Later Apr 16, 2026 54:25

You don't understand aging. You've been lied to about what's possible for the human body. You think the march toward old age and disease is inevitable, and that genetics are your destiny. The reality is, we're living through the greatest turning point in the history of human health—and most people have absolutely no idea just how fast it's all happening. What if I told you that not only can we slow the aging process, but that it's starting to look like we can actually reverse it? Thanks to the exponential power of AI and the most cutting-edge biotechnology, what used to take centuries and cost billions is now possible in months, for a fraction of the price. Today on Impact Theory, we are joined by a true pioneer who's redefining what it means to get old—someone at the intersection of AI, biology, and longevity: researcher, Harvard professor, and world-renowned expert on aging, Dr. Sinclair. Strap in, because this episode is packed with groundbreaking science, jaw-dropping experiments, and a vision for the future that will challenge everything you think you know about what it means to stay young. Let's dive in. What's up, everybody? It's Tom Bilyeu here: If you want my help... STARTING a business: join me here at ZERO TO FOUNDER: https://tombilyeu.com/zero-to-founder?utm_campaign=Podcast%20Offer&utm_source=podca[%E2%80%A6]d%20end%20of%20show&utm_content=podcast%20ad%20end%20of%20show SCALING a business: see if you qualify here.: https://tombilyeu.com/call Get my battle-tested strategies and insights delivered weekly to your inbox: sign up here.: https://tombilyeu.com/ ********************************************************************** If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu's Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you. ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Blinkist: Start your free trial at https://blinkist.com/impactQuince: Free shipping and 365-day returns at https://quince.com/impactpodIncogni: Take your personal data back with Incogni! Use code IMPACT at the link below and get 60% off an annual plan: https://incogni.com/impactAT&T Business: Switch to AT&T Business at business.att.comNetsuite: Right now, get our free business guide, Demystifying AI, at https://NetSuite.com/TheoryKetone IQ: Visit https://ketone.com/IMPACT for 30% OFF your subscription orderSumm: code TOMVIP20 for 20% off your first year at https://summ.com?via=tombilyeu&coupon=TOMVIP20Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impactCozy Earth: code IMPACT for 20% off https://cozyearth.comQuo: Try for free PLUS get 20% off your first 6 months at https://quo.com/impact Learn more about your ad choices. Visit megaphone.fm/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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"We Grew Human Brains in a Lab, Gave Them Alzheimer's, and Reversed It" | Impact Theory w. Tom Bilyeu & David Sinclair

Intermittent Fasting Stories

Play Episode Listen Later Apr 16, 2026 57:55

You don't understand aging. You've been lied to about what's possible for the human body. You think the march toward old age and disease is inevitable, and that genetics are your destiny. The reality is, we're living through the greatest turning point in the history of human health—and most people have absolutely no idea just how fast it's all happening. What if I told you that not only can we slow the aging process, but that it's starting to look like we can actually reverse it? Thanks to the exponential power of AI and the most cutting-edge biotechnology, what used to take centuries and cost billions is now possible in months, for a fraction of the price. Today on Impact Theory, we are joined by a true pioneer who's redefining what it means to get old—someone at the intersection of AI, biology, and longevity: researcher, Harvard professor, and world-renowned expert on aging, Dr. Sinclair. Strap in, because this episode is packed with groundbreaking science, jaw-dropping experiments, and a vision for the future that will challenge everything you think you know about what it means to stay young. Let's dive in. What's up, everybody? It's Tom Bilyeu here: If you want my help... STARTING a business: join me here at ZERO TO FOUNDER: https://tombilyeu.com/zero-to-founder?utm_campaign=Podcast%20Offer&utm_source=podca[%E2%80%A6]d%20end%20of%20show&utm_content=podcast%20ad%20end%20of%20show SCALING a business: see if you qualify here.: https://tombilyeu.com/call Get my battle-tested strategies and insights delivered weekly to your inbox: sign up here.: https://tombilyeu.com/ ********************************************************************** If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu's Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you. ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Blinkist: Start your free trial at https://blinkist.com/impactQuince: Free shipping and 365-day returns at https://quince.com/impactpodIncogni: Take your personal data back with Incogni! Use code IMPACT at the link below and get 60% off an annual plan: https://incogni.com/impactAT&T Business: Switch to AT&T Business at business.att.comNetsuite: Right now, get our free business guide, Demystifying AI, at https://NetSuite.com/TheoryKetone IQ: Visit https://ketone.com/IMPACT for 30% OFF your subscription orderSumm: code TOMVIP20 for 20% off your first year at https://summ.com?via=tombilyeu&coupon=TOMVIP20Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impactCozy Earth: code IMPACT for 20% off https://cozyearth.comQuo: Try for free PLUS get 20% off your first 6 months at https://quo.com/impact Learn more about your ad choices. Visit megaphone.fm/adchoices

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Episode 514: Peter Savich

Play Episode Listen Later Apr 16, 2026 55:40

In this episode of Intermittent Fasting Stories, Gin Stephens talks to Peter Savich from Hollister, CA.Join Gin in the new Fast Feast Repeat app for The Grown-Up Year: 52 Weeks to Listen, Play, and Nourish, as well as a growing collection of intermittent fasting resources. Go to app.fastfeastrepeat.com to join us or go to the App Store and download the Fast Feast Repeat app, available for both iPhone and Android.Are you ready to take your intermittent fasting lifestyle to the next level? There's nothing better than community to help with that. In the Delay, Don't Deny community we all embrace the clean fast, and there's just the right support for you as you live your intermittent fasting lifestyle. You can connect directly with Gin in the Ask Gin group, and she will answer all of your questions personally. If you're new to intermittent fasting or recommitting to the IF lifestyle, join the 28-Day FAST Start group. After your fast start, join us for support in The 1st Year group. Need tips for long term maintenance? We have a place for that! There are many more useful spaces beyond these, and you can interact in as many as you like. Visit ginstephens.com/community to join us. An annual membership costs just over a dollar a week when you do the math. If you aren't ready to fully commit for a year, join for a month and you can cancel at any time. If you know you'll want to stay forever, we also have a lifetime membership option available. IF is free. You don't need to join our community to fast. But if you're looking for support from a community of like-minded IFers, we are here for you at ginstephens.com/community. Peter is a patent consultant who embarked on his intermittent fasting journey not for weight loss, but to enhance his metabolic health. Peter shares how his interest in autophagy, sparked by a podcast featuring David Sinclair, led him to initially adopt a 20:4 fasting schedule. This approach has not only helped him maintain a healthy weight but also significantly reduced his biological age, showcasing the profound health benefits beyond mere weight management.Peter discusses the unexpected advantages of fasting, such as improved resilience to illnesses and enhanced metabolic flexibility. He recounts how his fasting routine, which began during the COVID-19 lockdowns, has transformed his health, allowing him to maintain muscle mass through strength training while experiencing a drop in weight. His story highlights the broader health benefits of fasting, emphasizing that it's not just about the numbers on the scale but about overall well-being and vitality.For those new to intermittent fasting, Peter advises focusing on the health benefits beyond weight loss. He encourages listeners to consider fasting as a tool for improving metabolic health and resilience, rather than just a weight loss strategy. By sharing his journey, Peter hopes to inspire others to explore the potential of fasting to unlock surprising health benefits and achieve a new level of wellness.Join Gin in the new Fast Feast Repeat app for The Grown-Up Year: 52 Weeks to Listen, Play, and Nourish, as well as a growing collection of intermittent fasting resources. Go to app.fastfeastrepeat.com to join us or go to the App Store and download the Fast Feast Repeat app, available for both iPhone and Android.Get Gin's books at: https://www.ginstephens.com/get-the-books.html. Good news! The second edition of Delay, Don't Deny is now available in ebook, paperback, hardback, and audiobook. This is the book that you'll want to start with or share with others, as it is a simple introduction to IF. It's been updated to include the clean fast, an easier to understand and more thorough description of ADF and all of your ADF options, and an all new success stories section. When shopping, make sure to get the second edition, which has a 2024 publication date. The audiobook for the second edition is available now! Join Gin's community! Go to: ginstephens.com/communityDo you enjoy Intermittent Fasting Stories? You'll probably also like Gin's other podcast with cohost Sheri Bullock: Fast. Feast. Repeat. Intermittent Fasting for Life. Find it wherever you listen to podcasts. Share your intermittent fasting stories with Gin: gin@intermittentfastingstories.comVisit Gin's website at: ginstephens.com Check out Gin's Favorite Things at http://www.ginstephens.com/gins-favorite-things.htmlSubscribe to Gin's YouTube Channel! https://www.youtube.com/channel/UC_frGNiTEoJ88rZOwvuG2CASee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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[SPECIAL SINGULARITY]

AI Unraveled: Latest AI News & Trends, Master GPT, Gemini, Generative AI, LLMs, Prompting, GPT Store

Play Episode Listen Later Apr 12, 2026 53:06

David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!

The Diary Of A CEO by Steven Bartlett

Play Episode Listen Later Mar 23, 2026 149:01

Scientist and Harvard professor Dr. David Sinclair, A.O., Ph.D., reveals his latest research on how to reverse ageing, insights into vitamins and supplements, why DNA is not your destiny, and the first clinical trials to reverse human ageing and blindness! Dr. David Sinclair is a world-renowned Professor of Genetics at Harvard Medical School and the leading authority on longevity science. He is Founder of Lifespan.com and multiple biotechnology companies, Co-Chief Editor of the journal Ageing, and bestselling author of ‘Lifespan: Why We Age - And Why We Don't Have To'. Dr. Sinclair explains: ◼️The “Information Theory of Aging” that regards ageing as a treatable disease ◼️Advances in resetting biological age using cellular “backup copies” ◼️His specific supplement stack for longevity ◼️Why fasting and “good stress” are science-based longevity strategies ◼️How his lab's gene therapy is being used to restore eyesight and reverse blindness Enjoyed the episode? Share this link and earn points for every referral - redeem them for exclusive prizes: https://doac-perks.com Follow David: Lifespan - https://link.thediaryofaceo.com/HKwBnm8 Instagram - https://linkly.link/2ajhU Podcast - https://linkly.link/2aji0 YouTube - https://link.thediaryofaceo.com/AiIza5B The Sinclair Lab - https://linkly.link/2ajhX You can purchase David's book, ‘Lifespan: Why We Age-and Why We Don't Have To', here: https://linkly.link/2ajhc The Diary Of A CEO: ◼️Join DOAC circle here - https://doaccircle.com/ ◼️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook ◼️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt ◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb ◼️Get email updates - https://bit.ly/diary-of-a-ceo-yt ◼️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb Sponsors: Bon Charge: https://boncharge.com/DOAC for 20% off Shopify - https://shopify.com/bartlett Ketone - https://ketone.com/STEVEN for 30% off your subscription order

Katie Herzog: The Science Behind Drinking To Get Sober

The Origins Podcast with Lawrence Krauss

Play Episode Listen Later Mar 23, 2026 130:53

Alcoholism is a scourge on modern society. Every year, 178,000 American die from alcohol abuse, and it has been estimated that over 200 billion dollars is lost from the US economy due to alcoholism, includingcosts of health care, lost productivity, and costs of crime enforcement. Given this immense social cost, it is equally amazing that there is no widely accepted cure. Rather, alcoholics are told they need to abstain from taking a single drink for the rest of their lives, or they are likely to revert to their earlier states of alcohol abuse. Katie Herzog is a journalist whose work I have enjoyed and I was happy to have a conversation with her in general. But even more so after the publication of her recent book, Drink your Way Sober. She discusses there a fascinating science-based approach that appears to provide a ‘cure' for many alcoholics that actually allows them to drink, if they wish, in moderation, for the rest of their lives. The idea is to use an opioid blocker, in this case something called naltrexone, that basically removes the pleasure response from drinking. A naltrexone pill can be taken a few hours before drinking, and over time, with the correct behavioral management, it has been shown to be effective for many drinking in removing the craving for alcohol.What makes Katie's book, and our discussion, so poignant is that Katie is not just a journalist writing about alcoholism, she was an alcoholic for most of her life, and her discovery of the work of of the so-called Sinclair Method, after the scientist David Sinclair, whose original work on naltrexone in Finland changed the field, changed her life. Her book intersperses her own experiences with the science underlying this new treatment for alcoholism, and it is thus perfect for our podcast, which connects science and culture. It also makes for a fascinating and informative conversation that I hope will help have a positive impact on treating this international blight. I hope you find it engrossing and as enjoyable to listen to as it was to produce.And there are still berths available on our Greece and Cyprus adventure. Go to originsproject.org and explore the possibilities!As always, an ad-free video version of this podcast is also available to paid Critical Mass subscribers. Your subscriptions support the non-profit Origins Project Foundation, which produces the podcast. The audio version is available free on the Critical Mass site and on all podcast sites, and the video version will also be available on the Origins Project YouTube. Get full access to Critical Mass at lawrencekrauss.substack.com/subscribe

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Is David Sinclair Wrong about Aging?

Healthy Lifestyle Made Simple With Rimon N. Lumen

Play Episode Listen Later Mar 7, 2026 8:27

Is David Sinclair Wrong about Aging?If you prefer to lead your health rather than react to decline, review the London Pilot here: https://www.clplongevityhub.com/✅ Get Rimon's 2026 updated supplement routine:https://Wellnessmessiah.com/List

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Mexican Cartel Biohacking, Google Anti-Aging Breakthrough, Measles Is Back, Age Reversal In 2026 : 1423

The Human Upgrade with Dave Asprey

Play Episode Listen Later Feb 27, 2026 9:22

This week's stories: Sinclair's This Is the Test: Are we about to see age reversal in humans? At the World Governments Summit 2026 in Dubai, Harvard geneticist David Sinclair told world leaders that ageing could soon be reversible and said the first human clinical trials of epigenetic reprogramming therapies are moving forward. The core idea is that ageing is partly an information problem, how cells read DNA, not just cumulative damage, and that partial reprogramming could restore youthful function without turning tissues into tumors. Dave frames this as a rare binary moment for longevity: either early, localized human trials (starting with tightly controlled tissue targets like the eye) show meaningful functional rejuvenation with acceptable safety, or the field has to recalibrate fast. Either way, the next couple of years will heavily influence where money, regulators, and serious researchers place their bets. • Sources: – World Governments Summit: https://www.worldgovernmentssummit.org/media-hub/news/detail/ageing-could-soon-be-reversible-says-harvard-scientist-at-wgs-2026 – NAD / Life Biosciences coverage: https://www.nad.com/news/fda-greenlights-life-biosciences-human-study-setting-up-pivotal-test-for-aging-theory-from-harvards-david-sinclair AlphaFold 4 in a locked box: DeepMind's private AI drug design engine Isomorphic Labs, DeepMind's drug discovery company, unveiled a proprietary drug design engine that outside scientists are comparing to an AlphaFold 4 moment, but for designing drugs, not just predicting structures. The big shift is that this system is closed: no public weights, no open database, and access appears to flow through partnerships with pharma companies. Dave breaks down why that matters for the longevity world: if AI makes early discovery cheaper and faster, we might see more serious shots on ageing targets over the next decade, but a closed model can also mean less transparency, bigger IP moats, and no guarantee that faster discovery leads to cheaper drugs. • Sources: – Nature: https://www.nature.com/articles/d41586-026-00365-7 – Isomorphic Labs: https://www.isomorphiclabs.com/articles/the-isomorphic-labs-drug-design-engine-unlocks-a-new-frontier Peptides in the freezer: El Mencho's anti aging stash and the dark side of wellness After reports and images from the final hideout linked to Jalisco New Generation Cartel leader Nemesio Oseguera Cervantes (El Mencho), coverage highlighted a detail that feels uncomfortably familiar to anyone in the modern wellness internet: injectable vials stored in a freezer with a schedule attached, including Tationil Plus, a glutathione based injectable marketed in some places for “cellular health,” cosmetic effects, and anti ageing. Dave uses the absurdity as a narrative wedge, not cartel gossip, to talk about how normalized gray market injectables have become, and how marketing (“detox,” “cellular reset”) often outruns evidence and safety. The segment pivots into a practical filter: which compounds are real therapeutics under medical supervision, and which are expensive folklore with sourcing risk and unknown long term downsides. • Sources: – New York Post: https://nypost.com/2026/02/25/world-news/inside-the-luxurious-love-nest-where-mexican-drug-lord-el-mencho-spent-his-final-days/ – Sky News (Reuters photos referenced): https://news.sky.com/story/inside-the-mexican-villa-where-feared-drug-lord-el-mencho-spent-final-hours-13511954 – Reuters photo gallery: https://www.reuters.com/pictures/el-menchos-last-hideout-inside-villa-where-cartel-leader-spent-final-hours-2026-02-25/W7DK5WEXS5IMLLZQO2P3CXGXFM The disease we thought was dead: measles comes roaring back Measles cases have surged in early 2026, with reporting citing at least 588 cases in the U.S. by late January, already more than many full year totals, and additional updates showing continued acceleration into February. Dave reframes this as a healthspan floor issue: you can argue about peptides and mitochondria all day, but measles is so contagious that once community immunity drops, outbreaks move fast and hit the most vulnerable first, especially infants and immunocompromised people. He also flags the systems problem: many clinicians have never seen measles, which increases the odds of delayed recognition and wider exposure in waiting rooms. The actionable move is boring and high ROI: verify MMR status for you and your family and close gaps before outbreaks get closer to home. • Sources: – AMA Morning Rounds (Week of Feb. 2, 2026): https://www.ama-assn.org/about/publications-newsletters/top-news-stories-ama-morning-rounds-week-feb-2-2026 – ABC News (CDC case count coverage): https://abcnews.com/Health/588-us-measles-cases-reported-january-cdc/story?id=129699078 – CIDRAP (case tracking context): https://www.cidrap.umn.edu/measles/us-measles-cases-soar-588-so-far-year-south-carolina-confirms-58-new-infections DC vs your health: Trump's State of the Union health reset President Donald Trump's 2026 State of the Union included a cluster of healthcare themes that function as a directional signal for agencies and payers this year, including drug pricing rhetoric, price transparency, and broader coverage and affordability framing. Dave translates the politics into a practical heuristic for biohackers: federal posture quietly determines what becomes easy versus painful to access in the legitimate system, from GLP 1 coverage rules and prior auth behavior to how friendly the environment is for telehealth, at home diagnostics, and eventually whatever “real longevity medicine” looks like. You do not need every policy detail in a weekly rundown, just the weather report: reimbursement and enforcement trends shape what stays niche, what scales, and what gets friction. • Sources: – Advisory Board: https://www.advisory.com/daily-briefing/2026/02/25/health-policy-roundup – Healthcare Dive: https://www.healthcaredive.com/news/trump-state-of-the-union-healthcare-2026/812962/ – This Week in Public Health analysis: https://thisweekinpublichealth.com/blog/2026/02/25/the-2026-state-of-the-union-what-it-means-for-health-and-public-health/ All source links are provided for direct access to the original reporting and research. This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on circadian biology, neurodegeneration signals, cognitive training, caffeine strategy, and supplement regulation. Host Dave Asprey connects emerging science, behavioral data, and policy shifts into practical frameworks you can use to build a resilient, adaptable health stack. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: David Sinclair age reversal, epigenetic reprogramming therapy, Yamanaka factors OSK, Life Biosciences clinical trial, human rejuvenation trial 2026, biological age reset, longevity breakthrough news, DeepMind Isomorphic Labs, AlphaFold 4 drug design, AI drug discovery engine, geroprotective drug development, peptide gray market risks, injectable glutathathione Tationil Plus, GLP-1 regulation FDA warning, wellness industry regulation, measles outbreak 2026 US, MMR vaccine status adults, vaccine trust public health, health policy 2026 State of the Union, GLP-1 access and reimbursement, telehealth longevity care, biohacking news, anti-aging research update Thank you to our sponsors! Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 - Introduction 0:30 - Story #1: David Sinclair 2026 2:13 - Story #2: Google Drug Discovery 3:48 - Story #3: El Mencho Biohacking5:30 - Story #4: Measles Outbreak 6:51 - Story #5: Trump State of the Union 8:00 - Weekly Roundup 9:10 - Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

270. Does MS Affect Brain Aging? What the Research Shows

The MSing Link

Play Episode Listen Later Feb 4, 2026 42:47

In this episode of The MSing Link Podcast, I'm thrilled to welcome Dr. Kelly Rich, neuroscientist at Harvard Medical School, for a deep dive into how multiple sclerosis (MS) might accelerate brain aging—and what the latest research reveals. We explore the connection between MS, cellular aging, and innovative new therapies like cellular reprogramming that could help protect and rejuvenate your nervous system. Dr. Rich shares practical insights on supporting brain health, resilience, and ways to slow neurological decline. Whether you're looking to reduce MS fatigue, improve mobility, or boost your cognition, this episode is packed with expert advice, empowering exercises, and actionable tools for living better with MS. Tune in for an inspiring discussion on MS treatments, neuroscience, anti-inflammatory strategies, and hope for future breakthroughs in MS care! About Dr. Kelly Rich: Dr. Kelly Rich, a neuroscientist and clinical genetic counselor at Harvard Medical School, who works in Dr. David Sinclair's lab studying how aging affects our nervous system at the cellular level. Connect with Dr. Kelly Rich:Instagram: https://www.instagram.com/kellyrichphd Connect with the Sinclair Lab:Instagram: https://www.instagram.com/sinclair_labWebsite: https://sinclair.hms.harvard.edu/?utm_source=ig&utm_medium=social&utm_content=link_in_bio&fbclid=PAZXh0bgNhZW0CMTEAc3J0YwZhcHBfaWQMMjU2MjgxMDQwNTU4AAGnPtOlP1oSYiX1wyDKp-8TxE5-kbY81__aH1AWVU_qn2JJGn-dihYq4uHn6Wg_aem_7n-6t_jlL2A68qgb0q7bVALifespan with Dr. David Sinclair Podcast: https://podcasts.apple.com/us/podcast/lifespan-with-dr-david-sinclair/id1601709306 Additional Resources: https://www.doctorgretchenhawley.com/insider Reach out to Me: hello@doctorgretchenhawley.com Website: www.MSingLink.com Social: ★ Facebook: https://www.facebook.com/groups/mswellness ★ Instagram: https://www.instagram.com/doctor.gretchen ★ YouTube: https://www.youtube.com/c/doctorgretchenhawley?sub_confirmation=1 → Game Changers Course: https://www.doctorgretchenhawley.com/GameChangersCourse → Total Core Program: https://www.doctorgretchenhawley.com/TotalCoreProgram → The MSing Link: https://www.doctorgretchenhawley.com/TheMSingLink

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Days with Bowie, Prince, the Stones, Hendrix & the Clash by David Sinclair

Word Podcast

Play Episode Listen Later Feb 2, 2026 62:16

David Sinclair was a long-running rock critic for the Times, Rolling Stone and many others and now makes records himself. He looks back here at some of the first bands he saw and the extraordinary people he interviewed, which touches on … … the day Bowie took him to the Hammersmith Odeon to stand on the spot where he announced his retirement … Keith Richards' dark side (and what he said about Lady Di) … interviewing Prince “who seemed like a shadow” … seeing Free in 1970: “I still think about it. Some bands are like footprints in fresh snow” … Hendrix on a bill with Cat Stevens and the Walker Brothers when he was 14 … singles he wore out in the days when you had to change the needle … his theory about the lyrics of Crossroads … “the Simon Templar of rock journalism” … the purgatory of being a serious musician when Spotify adds 100,000 new tracks a day … and the Shadows, the Scorpions, Sting, ZZ Top, David Coverdale and … Millstone Grit. David Sinclair's music here: https://open.spotify.com/artist/4oMczlXHj1pt6M4ZNGR14E?si=_9Dx_G_UQ3GifCFGFra07A To buy here: https://www.davidsinclairfour.com/shop Tickets to the 100 Club, May19: https://www.solidentertainments.com/100club/index.htmlHelp us to keep the conversation going: https://www.patreon.com/wordinyourear Hosted on Acast. See acast.com/privacy for more information.

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Days with Bowie, Prince, the Stones, Hendrix & the Clash by David Sinclair

Word In Your Ear

Play Episode Listen Later Feb 2, 2026 62:16

David Sinclair was a long-running rock critic for the Times, Rolling Stone and many others and now makes records himself. He looks back here at some of the first bands he saw and the extraordinary people he interviewed, which touches on … … the day Bowie took him to the Hammersmith Odeon to stand on the spot where he announced his retirement … Keith Richards' dark side (and what he said about Lady Di) … interviewing Prince “who seemed like a shadow” … seeing Free in 1970: “I still think about it. Some bands are like footprints in fresh snow” … Hendrix on a bill with Cat Stevens and the Walker Brothers when he was 14 … singles he wore out in the days when you had to change the needle … his theory about the lyrics of Crossroads … “the Simon Templar of rock journalism” … the purgatory of being a serious musician when Spotify adds 100,000 new tracks a day … and the Shadows, the Scorpions, Sting, ZZ Top, David Coverdale and … Millstone Grit. David Sinclair's music here: https://open.spotify.com/artist/4oMczlXHj1pt6M4ZNGR14E?si=_9Dx_G_UQ3GifCFGFra07A To buy here: https://www.davidsinclairfour.com/shop Tickets to the 100 Club, May19: https://www.solidentertainments.com/100club/index.htmlHelp us to keep the conversation going: https://www.patreon.com/wordinyourear Hosted on Acast. See acast.com/privacy for more information.

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Days with Bowie, Prince, the Stones, Hendrix & the Clash by David Sinclair

Word In Your Ear

Play Episode Listen Later Feb 2, 2026 62:16

David Sinclair was a long-running rock critic for the Times, Rolling Stone and many others and now makes records himself. He looks back here at some of the first bands he saw and the extraordinary people he interviewed, which touches on … … the day Bowie took him to the Hammersmith Odeon to stand on the spot where he announced his retirement … Keith Richards' dark side (and what he said about Lady Di) … interviewing Prince “who seemed like a shadow” … seeing Free in 1970: “I still think about it. Some bands are like footprints in fresh snow” … Hendrix on a bill with Cat Stevens and the Walker Brothers when he was 14 … singles he wore out in the days when you had to change the needle … his theory about the lyrics of Crossroads … “the Simon Templar of rock journalism” … the purgatory of being a serious musician when Spotify adds 100,000 new tracks a day … and the Shadows, the Scorpions, Sting, ZZ Top, David Coverdale and … Millstone Grit. David Sinclair's music here: https://open.spotify.com/artist/4oMczlXHj1pt6M4ZNGR14E?si=_9Dx_G_UQ3GifCFGFra07A To buy here: https://www.davidsinclairfour.com/shop Tickets to the 100 Club, May19: https://www.solidentertainments.com/100club/index.htmlHelp us to keep the conversation going: https://www.patreon.com/wordinyourear Hosted on Acast. See acast.com/privacy for more information.

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Dr. Aubrey de Grey: Why We Will Defeat Aging in Our Lifetime (and How You Can Help)

TrueLife

Play Episode Listen Later Dec 10, 2025 65:04

One on One Video Call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_USThe Lila Code: https://orcid.org/0009-0008-4612-3942

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CBP 288: Recurring Cash-Pay Revenue in Private Practice – How to Get Yeses to your Maintenance Memberships

The Cash-Based Practice Podcast

Play Episode Listen Later Nov 1, 2025 17:48

Every practice owner wants consistent, predictable revenue—and the best way to earn this are patients who keep coming back because you continue to transform their life, and they truly value what you provide. That's exactly what continuity and maintenance memberships can create. In this episode, I walk through the most effective strategies for getting more patients to say "yes" to your ongoing care memberships—without feeling salesy or pushy, or offering them anything that wouldn't be of significant value to them.. And since this episode releases right around Halloween, I'll start with a quick personal update.

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Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Huberman Lab

Play Episode Listen Later Oct 30, 2025 39:07

In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, regular exercise and NAD⁺-boosting compounds like NMN, can activate the body's natural longevity pathways. This discussion highlights how lifestyle choices profoundly influence the aging process and may even slow or reverse key aspects of biological aging. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (0:00) David Sinclair (0:20) Longevity, Anti-Aging, Aging as a Disease (2:27) Causes of Aging; Epigenome & Genes (4:53) CD & Scratches Analogy, DNA, Silencing & Expressing Genes (6:44) Physical Appearance & Aging (7:36) Sponsor: David (8:54) Childhood Development & Aging, Horvath Clock, Accelerate Aging (11:30) Rates of Puberty & Aging, Growth Hormone (12:37) Body Size & Longevity; Epigenetics (13:07) Fasting, Calorie Restriction & Longevity, Sirtuins, Insulin & Glucose (16:31) Tool: Skip a Meal (17:07) Longer Fasts & Autophagy, “Deep Cleanse” (18:07) Sponsor: AGZ by AG1 (19:36) Fasting, Fluids, Electrolytes (20:16) Sirtuins, Glucose, mTOR & Fasting; Leucine, Tool: Pulsing Behaviors (24:24) Breaking a Fast, Tools: Do Your Best; Transitions (27:00) Sirtuins, NAD, NMN Supplementation (29:04) Sponsor: Eight Sleep (31:10) Iron & Senescent Cells; Personalize Medicine (32:40) Tool: Blood Markers, CRP (34:50) Tool: Aerobic & Resistance Exercise (35:55) Estrogen, Fasting & Fertility; Aging & Rejuvenation (38:20) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode 153: Age Reversal Fueled by AI

Exponential Wisdom

Play Episode Listen Later Oct 24, 2025 26:06

Dan Sullivan and Peter Diamandis dive into the evolving concept of longevity, reframing it as age reversal. They discuss the ground-breaking work of David Sinclair, a leading researcher at Harvard Medical School, and his contributions to epigenetic age reversal. The conversation highlights the public's perception of aging and longevity, emphasizing the desire for not just a longer life, but a healthier and more vibrant one. In this episode: The shift from longevity to age reversal is now a more immediate and measurable goal in health and wellness. AI and robotics is accelerating research and development in age-reversal therapies and diagnostics. Muscle strength, particularly leg strength, is a key indicator of longevity and overall health.

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#232 NAD+, Energy & Longevity: How to Restore Cellular Power Naturally | Dr. Dan Pardi @Qualia

Mind Body Peak Performance

Play Episode Listen Later Oct 23, 2025 86:05

Ever wonder why your energy fades faster as you age? Dr. Dan Pardi of Qualia Life Sciences explains how NAD+ supports metabolism, DNA repair, & brain health, & how simple bioharmonizing habits can restore your cellular power naturally. Meet our guest Dr. Dan Pardi is the Chief Health Officer at Qualia Life Sciences, where he designs health-improvement journeys, guided protocols & education systems that simplify complex science for lasting results. Formerly the founder & CEO of humanOS.me & Chief Health Architect at Restore Hyper Wellness, he's led collaborations with top researchers, military units & wellness organizations. With a PhD in Cognitive Neuroscience & a background in Exercise Physiology, Dr. Pardi empowers people & institutions to master healthspan, performance & resilience through science-backed systems. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways NAD existed before life & kickstarted living processes NAD+ is a universal coenzyme that transfers energy across all cells, keeping you alive & well Enzymes act like machines while coenzymes (NAD+) serve as the tools they need to work NAD+ sits at the center of all metabolic processes, regulating glucose, building, & breaking down substances Mainstream interest in NAD+ surged after Dr. David Sinclair's book Lifespan hit shelves around 2017 NAD+ levels drop every decade, leading to less energy & slower cellular repair with age Sun exposure both helps & harms Too much damages DNA & drains NAD+ through increased repair demands Chronic inflammation & DNA damage reduce NAD+ levels faster, causing energy loss & fatigue Oral NAD+ precursors boost cellular energy more efficiently than IV NAD+ for daily health with fewer side effects Good sleep, regular exercise, & healthy habits maintain NAD+ levels, slowing aging & improving performance Episode highlights 0:00 Why NAD+ is the spark of life 01:44 How NAD+ fuels energy & longevity 11:15 Why NAD+ declines & how to preserve it 25:22 Choosing the right NAD+ strategy 48:31 Lifestyle habits that protect NAD+ 51:31 Signs your NAD+ is running low Links Watch it on YouTube: https://youtu.be/QKtf71Othu0 Full episode show notes: outliyr.com/232 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

#127 - David Sinclair

The Steep Stuff Podcast

Play Episode Listen Later Oct 16, 2025 76:40 Transcription Available

Send us a textTen hours on the edge, a live stream watched by hundreds of thousands, and a second-place finish that announced David Sinclair to the world stage. We unpack how an injury scare turned into a smarter build, why he chose CCC over OCC, and the exact training and fueling choices that helped him lead for hours, survive the low points, and find the grit to hold the podium in Chamonix.David takes us inside the chaos at Worlds—from canceled flights to a sky-high vert profile—and what that taught him about specificity and course targeting. Then we go deep on the nuts and bolts: threshold-focused workouts drawn from his ski background, a summer of cross-training and uphill-only running, and the course recon that let him pace with intent. We break down his fueling strategy in plain terms—80 to 100 grams of carbs per hour, flavor fatigue management, and why separating carbs, fluids, and electrolytes can save your stomach late. With Western States on the horizon, he shares a practical heat plan: steady sauna work, relentless ice at every aid, and simple systems that keep core temperature down without overcomplicating race day.We also talk shoes and gear, including Craft prototypes that balance cushioning with stability on runnable terrain, and why East Coast training—rolling dirt roads, rooty steeps, variable weather—can build world-class durability without altitude. David's philosophy is refreshingly clear: keep it fun, stay flexible, and double down on the basics that actually move the needle. If you're mapping your next build or just love a front-row view of a breakthrough season, this conversation is a masterclass in turning setbacks into fuel.If this episode adds value to your training, follow the show, share it with a friend, and leave a quick rating or review. Your support helps us bring on more voices you'll want to learn from.Follow David on IG - @david.a.sinclair.92Follow James on IG - @jameslaurielloFollow the Steep Stuff Podcast on IG - @steepstuff_podUse code steepstuffpod for 25% off your cart at UltimateDirection.com!

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Jeff Krasno: The Hard Truth About Chasing Your Dreams

A Life of Greatness

Play Episode Listen Later Oct 13, 2025 63:19

He is the co-founder of Wanderlust, a global movement that has brought together millions through yoga, mindfulness and community. Yet Jeff Krasno's story stretches far beyond festivals and studios.In this thoughtful and inspiring conversation, Jeff joins Sarah Grynberg to share the lessons of a life spent at the intersection of wellness and culture, from building Wanderlust into a worldwide phenomenon, to creating Commune Media, where he amplifies the voices of the world's leading teachers and thinkers. With honesty and depth, he explores the power of community, the role of spirituality in modern life, and why belonging is one of our most vital medicines.You'll learn:*Why community and connection are central to true healing.*How mindfulness and spirituality can ground us in a chaotic world.*What Jeff has learned about growth, resilience and meaning from building global movements.This episode is a moving reminder that wellness is not just a personal journey, but a shared one, and that the path to healing and purpose is often found together.Wanderlust WELLSPRING - October 25 & 26, 2025 in the Gold CoastSee Jeff alongside Kayla Barnes, Dave Asprey, Wim Hof, Dr David Sinclair, Dr Gabrielle Lyon, Dr Will Cole Plus 40 more! I'll be there too! Tickets on sale now via Humanitix, from $250 See more at wanderlust.com.au/eventsPurchase Sarah's book: Living A Life Of Greatness here.To purchase Living A Life of Greatness outside Australia here or here.Watch A Life of Greatness Episodes On Youtube here.Sign up for Sarah's newsletter (Greatness Guide) here.Purchase Sarah's Meditations here.Instagram: @sarahgrynberg Website: https://sarahgrynberg.com/Facebook: facebook.com/sarahgrynbergTwitter: twitter.com/sarahgrynberg Hosted on Acast. See acast.com/privacy for more information.

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#126 - Tyler McCandless

The Steep Stuff Podcast

Play Episode Listen Later Oct 13, 2025 48:22 Transcription Available

Send us a textThe race began before the gun—shoulder to shoulder, 12 rows deep, with a call-up protocol that flipped expectations and turned the opening meters into a high-stakes fight for position. From a fast frontage road into stairs and tight singletrack, Tyler McCandless had to manage chaos without panic: protect effort, find clean lines, and pass only when it counted. What followed was a masterclass in patience and presence—steady gains through the forest, a fierce late surge on a 30% wall to the summit, and a finish that helped Team USA lock down bronze at the World Mountain Running Championships in Confranc.We get into the texture of Worlds that you can't see on a results sheet: the camaraderie of sharing meals with athletes you'd never usually race alongside, the electricity of cheering other disciplines all week, and the way team identity changes how you suffer. Tyler breaks down the travel and course recon with Joe Gray, the jet lag fix that worked, and the quiet confidence that came from previewing key sections. We also revisit Broken Arrow VK—how a last-minute course change erased the runnable grind he wanted, why he still qualified under pressure, and what it feels like to crest steep singletrack with David Sinclair closing fast.There's gear talk too—Nike's radical cooling long sleeve, why it's more than a fashion statement, and how innovation is finally meeting trail reality. Then we look ahead: a winter marathon bid to punch a fifth Olympic Trials ticket (sub-2:16), plus a summer slate that fits Tyler's engine—Sierre-Zinal, Pikes Peak Ascent, and select Golden Trail races. And we make the case for a dedicated U.S. uphill series to cultivate specialists, build team culture, and grow the fan base with short, watchable vertical races.If you enjoy stories of resilience, smart racing on steep ground, and the power of team over self, you'll want to queue this one up. Hit follow, share it with a trail friend, and leave a quick review—what part of Tyler's strategy would you try on your next climb?Follow Tyler on IG - @tracktyFollow James on IG - @jameslaurielloFollow the Steep Stuff Podcast on IG - @steepstuff_podUse code steepstuffpod for 25% off your cart at UltimateDirection.com!

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Episode #55: Beast Coast Beast Mode with David Sinclair

The Running Kind Podcast

Play Episode Listen Later Oct 10, 2025 58:14

Today Aimee is joined by David Sinclair, a Craft mountain athlete that has been tearing up the scene for years now. He had a stellar race, most recently placing second at CCC at UTMB in France a few weeks ago. Though this is his most recent accomplishment, he holds the course record at JFK 50, won the USATF 50K championships, and was named #3 Ultrarunner of the Year last year… among a long list of impressive race finishes. You can find more information about The Running Kind here. https://therunningkind.net/ https://www.facebook.com/groups/therunningkind/ @therunningkind_ Aimee Kohler Founder of The Running Kind @aimskoh Produced by Aimee Kohler Music Dim Red Light by Don Dilego

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The Hidden Ingredient That Could Transform Your Health with guest expert Serena Poon

Your Healthiest Healthy with Samantha Harris

Play Episode Listen Later Oct 7, 2025 38:41

The Hidden Ingredient That Could Transform Your Health with guest expert Serena PoonIs This Serving Me?It's easy to forget that food nourishes more than just the physical body—it also feeds our emotional and energetic selves. Some meals are more than just nutrients on a plate; they're prepared with intention, love, and care—and that makes a difference.Yes, love is an actual ingredient. You might've heard of “Vitamin L”—that invisible but powerful energy you infuse into meals when cooking for someone you care about. That's energetic nutrition. And when we approach food with this kind of consciousness, we feed our whole being: physical, emotional, and spiritual.A simple practice I share with my community—and I'd love to offer yours—is to turn your gratitude practice toward food. Even if you don't currently have a daily gratitude routine, it's never too late to start. Begin by taking a quiet moment before meals to offer thanks—not just for the food itself, but for how it supports your entire being.In this episode, you will learn:Importance of preparing food with love (“Vitamin L”)The role of gratitude while preparing mealsImpact on physical, emotional, and energetic bodiesMindful inquiry: Is this serving me right now?Eating from joy vs. eating from stressSelf-Compassion in Health PracticesAcknowledging the challenge of maintaining routines (e.g., diet, exercise, meditation)Transcendental Meditation (TM) as a Healing ToolEncourages forgiveness and non-judgmentGratitude Practices for Holistic HealthIntegrating gratitude into daily ritualsUnderstanding Food Cravings HolisticallyDifferentiating physiological needs (e.g., magnesium from chocolate) from emotional cravings… And much more.About our guest expert: Serena PoonSerena Poon, CN, CHC, CHN is a certified nutritionist, celebrity chef, Reiki Master, and wellness advisor to A-list clients including Tom Brady and Sofía Vergara. She is the founder of Serena Loves®, Just Add Water®, and creator of Culinary Alchemy®, her method of blending functional and spiritual nutrition to nourish the body, mind, and soul.She co-founded Fully Aligned Co. with Dr. David Sinclair to bridge the science and soul of well-being™, and also serves as Head of Development at the Academy for Health & Lifespan Research. Serena's expertise has been featured in Forbes, Vogue, The Wall Street Journal, TODAY, and The New York Times, and she's a regular contributor on KTLA Morning News.Instagram: @chefserenapoon****************************************Get Jumping!! Rebounder Workouts = Cardio without ImpactI loooove my rebounder mini-trampoline workouts. Why? Efficient cardio without high-impact hurting my joints + the bonus of improving lymphatic flow.It's a great 1-2 punch to get a high energy, low-impact sweat on with the added benefit of using the trampoline as a step, bench and other uses to allow for building muscle (especially when you add-on the strength training kit for a true muscle-building workout!).You can even use code: SAMANTHA10 for 10% off fitness trampolines model 250 or higher. Just click HERE or visit:

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David Sinclair | World Championships Pre-Race Interview 2025

Play Episode Listen Later Sep 24, 2025 22:47

This show is part of Freetrail's coverage of the 2025 World Mountain & Trail Running Championships. Our shows and athlete interviews are hosted by Dylan Bowman who sits down to talk with some of the favorites from Team USA who are racing this year. Dylan sits down with David Sinclair (Craft) in advance of his race at the 2025 World Championships. David is racing the Short Trail on Friday. Make sure to tune into all of Freetrail's coverage leading into the 2025 World Championships: Tuesday September 23rd: Top 10 Storylines of the 2025 World Championships Wednesday September 24th: Opening Ceremony Recap + Uphill Preview Thursday September 25th: Uphill Recap + Short Trail Preview Friday September 26th: Short Trail Recap + Long Trail Preview Saturday September 27th: Long Trail Recap + Classic Preview Sunday September 28th: Short Trail Recap + Worlds Week Wrap Up Make sure to play Freetrail's own fantasy trail running at https://fantasy.freetrail.com/events for a chance to win sweet prizes including Freetrail swag and special items from our partners at Nike ACG! Our 2025 World Championships coverage is brought to you by Nike ACG (All Conditions Gear). Make sure to check out All Conditions Gear footwear and apparel. All Conditions Gear is the official partner of USA Team and the Racing Department. All Conditions Gear is designed, tested, and made on planet earth specifically for trail running. You can learn more and check out the latest ACG gear at allconditionsgear.com We're super grateful for their support! Freetrail Links: Website | https://freetrail.com/ Freetrail Pro | https://freetrail.com/pro/ Patreon | / dylanbowman Instagram | https://www.instagram.com/runfreetrai... YouTube | / @freetrail Freetrail Experts | https://freetrail.com/experts/ Dylan Links: Instagram | https://www.instagram.com/dylanbo/?hl=en Twitter | https://twitter.com/dylanbo?lang=en LinkedIn | / dylan-bowman-06174380

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Broken Arrow 46k Men's Podium - Eli Hemming, David Sinclair, Ryan Becker

Play Episode Listen Later Jun 22, 2025 28:54

Dylan sits down for a post-race interview with the men's podium from today's Broken Arrow 46k: Champion Eli Hemming (Terrex), 2nd place David Sinclair and 3rd place Ryan Becker after their incredible battle today. David and Ryan will be headed to Spain in September to represent Team USA in the Short Trail event. Eli has his sites set on OCC by UTMB in August and is evaluating if he can do both. Congratulations, Eli, David and Ryan! Want to learn more about Freetrail? Check out Freetrail.com to learn more and consider joining our membership community, Freetrail Pro, to be part of the best global online community of passionate trail runners. Best sport in the world! Make sure to play Freetrail's own fantasy trail running at https://fantasy.freetrail.com/events. Don't forget to pick your favorite athletes in Freetrail Fantasy at fantasy.freetrail.com for your chance to win sweet prizes. Our Broken Arrow coverage is brought to you by our good friends at HOKA. We're grateful for their generous support and belief in Freetrail. Make sure to check out the latest and greatest from HOKA, the Mafate X. The Mafate X is all about innovation and pushing past limits. HOKA evolved their max-cushion trail experience to provide the confidence, control, and adaptability ultra runners require for their biggest trail efforts. Embracing the paradox of max cushion and stability on trail to develop a new experience for the longest adventures. You can learn more and shop here: https://www.hoka.com/en/us/mafate/ Freetrail Links: Website | https://freetrail.com/ Freetrail Pro | https://freetrail.com/freetrail-pro/ Patreon | / dylanbowman Instagram | https://www.instagram.com/runfreetrai... YouTube | / @freetrail Freetrail Experts | https://freetrail.com/freetrail-experts/ Dylan Links: Instagram | https://www.instagram.com/dylanbo/?hl=en Twitter | https://twitter.com/dylanbo?lang=en LinkedIn | / dylan-bowman-06174380 Strava | / strava

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Broken Arrow 46k Recap & 23k Preview