Podcasts about pragmatic

Pragmatic Powerlifting with Michael Greeno Grab my

HEADLINE: GAIUS & GERMANICUS IN LONDINIUM 91 AD: Discussing the Pragmatic 28-Point Plan for Ukraine. Broadcasting live from Londinium, where the Thames is too rough for boatmen due to the grim weather, Gaius and Germanicus analyze the 28-point plan aimed at ending the Ukrainian disruption. This plan, a multiple of Wilson's 14 points, is driven by an emperor in Washington, and the Kremlin is currently prevailing. The core provision involves the ceding of territory, specifically Donbas, to Russia, followed by Russian-won elections. Unlike the disastrous Versailles Treaty that led to future conflict, the 28 points are deemed pragmatic, solving the issue of ardent Russian nationalists within Ukraine's borders. The plan also prevents Ukraine from joining NATO and offers Russia reintegration into the world order, potentially rejoining the G8. The speakers agree the solution is positive, allowing Ukraine to survive as a sovereign nation while losing only territories that did not want to be a part of it. 1037

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There is only one successful way to adopt new technology, and that is transformational! Sounds like a high-level consulting pitch but our industry has a track record to validate this statement. Just look at the recent web or cloud-native transformations!Pini Reznik has been helping organizations along the current AI-Native transformational journey. And what a timing: He just published his book on From Cloud Native to AI-Native where he provides a pragmatic approach to leveraging AI from Pioneering to Gradually Scaling!Tune in and hear from Pini why he thinks that AI projects are not failing because of bad AI, but because they approaching the problem the old and wrong way!And, stay until the end to hear how it was to write a book about AI using AI!Links we discussedPini's LinkedIn: https://www.linkedin.com/in/pinireznik/Link to Book: https://re-cinq.com/bookOur previous episode: https://www.spreaker.com/episode/ai-native-the-next-revolution-after-cloud-native-with-pini-reznik--67692567Prompt Engineering Conference Talk: https://www.youtube.com/watch?v=W7z5XMnvYt8

What are the political and human risks of a world increasingly defined by transactional politics and national interests? Björn Holmberg, executive director of the Dag Hammarskjöld Foundation, joins the "Values & Interests" podcast to discuss the power of pragmatic idealism across international relations, the need to inject morality into the practice of geopolitics without moralizing, and how we can create realistic conditions for greater global cooperation. For more, please go to: https://carnegiecouncil.co/values-interests-holmberg

Send us a textNetworks can sometimes feel like a maze of licenses, tunnels, and 2 a.m. pager alerts. We sit down with Graphiant CEO Ali Shaikh to unpack how Network as a Service makes connectivity on-demand, consumption-based, and finally as flexible as the cloud it serves. From the SD-WAN wave to the pandemic reset, Ali explains why the old build-and-forget model couldn't keep pace with multi-cloud, remote work, and fast-moving partnerships—and how a stateless, metadata-driven fabric changes the game.We explore two clear buyer paths. Pragmatic teams want turnkey connectivity that lowers cloud egress costs, reduces NAT and transit complexity, and keeps operations calm. Futuristic teams need dynamic, auditable data exchanges for AI workloads, research projects, and payments ecosystems—publisher-subscriber connectivity that negotiates policy and stands up in days, not quarters. In both cases, the network becomes evergreen, with new capabilities landing in the service rather than hidden behind feature licenses. Pay for what you move, not for buttons you can't press.Security shifts from signatures to assurance. In an AI-fueled threat landscape, we focus on what should move, where it may travel, and who can subscribe—then we detect anomalies and lock down exfiltration. Ali digs into continuous audit trails, sovereignty-aware routing, and why pushing complexity to the edges keeps the core lean and reliable. Expect candid talk on cloud cost traps, how to cut NAT sprawl, and the reason a hollow core with metadata labels beats hop-by-hop state.If you're ready to trade SKU spreadsheets for clear outcomes—and want a network that can spin up for a week and tear down without drama—this conversation will reset how you think about connectivity. Subscribe, share with a teammate who owns the cloud bill, and drop a review to tell us where ephemeral networking would save you the most.Connect with our guest:https://www.linkedin.com/in/alifshaikh/https://www.graphiant.comPurchase Chris and Tim's book on AWS Cloud Networking: https://www.amazon.com/Certified-Advanced-Networking-Certification-certification/dp/1835080839/ Check out the Monthly Cloud Networking Newshttps://docs.google.com/document/d/1fkBWCGwXDUX9OfZ9_MvSVup8tJJzJeqrauaE6VPT2b0/Visit our website and subscribe: https://www.cables2clouds.com/Follow us on BlueSky: https://bsky.app/profile/cables2clouds.comFollow us on YouTube: https://www.youtube.com/@cables2clouds/Follow us on TikTok: https://www.tiktok.com/@cables2cloudsMerch Store: https://store.cables2clouds.com/Join the Discord Study group: https://artofneteng.com/iaatj

Stephen Grootes speaks to Minerals Council SA CEO Mzila Mthenjane about the B20 energy mix and just transition dialogue, where South Africa’s mining and industrial leaders stressed that the country’s energy transition must be pragmatic, policy-stable, and collaborative to unlock its mineral and industrial potential. The Money Show is a podcast hosted by well-known journalist and radio presenter, Stephen Grootes. He explores the latest economic trends, business developments, investment opportunities, and personal finance strategies. Each episode features engaging conversations with top newsmakers, industry experts, financial advisors, entrepreneurs, and politicians, offering you thought-provoking insights to navigate the ever-changing financial landscape.    Thank you for listening to a podcast from The Money Show Listen live Primedia+ weekdays from 18:00 and 20:00 (SA Time) to The Money Show with Stephen Grootes broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3Nk For more from the show, go to https://buff.ly/7QpH0jY or find all the catch-up podcasts here https://buff.ly/PlhvUVe Subscribe to The Money Show Daily Newsletter and the Weekly Business Wrap here https://buff.ly/v5mfetc The Money Show is brought to you by Absa     Follow us on social media   702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/CapeTalk 702 on YouTube: https://www.youtube.com/@radio702   CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/Radio702 CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

Process innovation in the pharmaceutical industry is never easy, but its best chance of success comes when companies come together to work on big problems – especially when they bring in regulators and other stakeholders.   In today's episode of the pharmaphorum podcast, host Jonah Comstock speaks with Rob DiCicco, vice president of portfolio management at TransCelerate Biopharma, a membership organisation where big pharma companies work together to innovate around the discovery, development, and manufacturing of new drugs.   DiCicco gives an update on TransCelerate's work with pragmatic trials and the group's meetings last year with the FDA. He discusses what pragmatic trials are and how they can improve the efficiency of clinical research, as well as describing the work that was done at the meeting last year and the report that's come out of it.   He also gets into next steps, how the new administration has and hasn't affected the work TransCelerate is doing with the FDA, and the role TransCelerate plays in taking these recommendation and putting them into practice.   Tune in to learn how the pharma industry is working together to change the way clinical trials are done.

Our very special guest today is Angus Fletcher, professor of story science at Ohio State's Project Narrative. His research has been called “life-changing” by Brené Brown and “mind blowing” by Malcolm Gladwell; has been endorsed by psychologists, neuroscientists, and doctors such as Martin Seligman and Antonio Damasio; and has been supported by institutions ranging from the National Science Foundation to the Academy of Motion Picture Arts and Sciences. In 2023, he was awarded the Commendation Medal by the U.S. Army for his “groundbreaking research” with U.S. Army Special Operations into primal intelligence. His latest book is called Primal Intelligence: You Are Smarter Than You Know. There are very few books or writers who have affected me as much as Angus and this book have. In the few weeks since I have read it, my coaching has changed. My thoughts about intuition, imagination and emotion have changed. I've watched close to 20 videos featuring Angus on youtube… and I don't typically ever watch that many videos about one person. Dr. Fletcher says that as humans, we think in story, not in words or pictures. He has plenty of research and street cred to back this up. Hollywood studios consult with him regularly. In addition to everything else, he's a screenwriter, and a very compelling author. I could go on and on but that wouldn't leave much time for us to talk, would it? So I will start with something familiar, and soon you will discover how mind-blowingly different some of Angus's groundbreaking ideas are. But first, the amazingly familiar part… Copy is powerful. You're responsible for how you use what you hear on this podcast. Most of the time, common sense is all you need. But if you make extreme claims... and/or if you're writing copy for offers in highly regulated industries like health, finance, and business opportunity... you may want to get a legal review after you write and before you start using your copy. My larger clients do this all the time. 1. A lot of people in the direct marketing community have felt boxed-in by the conventional wisdom that the only true kind of story is a hero's journey. I believe you have a very different point of view about stories, that includes that anatomy of the brain. Could you tell us about it? 2. Let's talk about primal intelligence. When I first found out about your book and before I read it, my guess about primal intelligence was, well, pretty primal. Lizard brain stuff. That is, the animal description that you either mate with something, or you kill it, or you eat it. You have a different and I think much more sophisticated and I would say much more useful definition of primal intelligence and it has to do with four qualities of thinking that have nothing to do with logic. Could you talk about that? 3. Our listeners are copywriters and business owners who use direct response copy in their businesses. Pragmatic creativity is high on the list of capabilities people always want to increase. Could you share your thoughts on what creativity is, from the point of view of primal intelligence? And how to increase our abilities to be creative? 4. In your book there's a surprisingly long list of people, including politicians, scientists and even a famous classical composer, as well as writers, who have mentioned Shakespeare as a major influence in their lives. What is it about Shakespeare's work that is so valuable to all these people? 5. Can you give us some more tips about using stories in our content and advertising that will capture people's attention and help us with our businesses? 6. Tell us about your work with Army special operators? 7. Would you like to give us a preview of the book Primal Intelligence? Links: Primal Intelligence https://www.amazon.com/Primal-Intelligence-Smarter-Than-Know/dp/0593715306 Angus's LinkedIn Address https://www.linkedin.com/in/angus-fletcher-99713617/ Download.

Rep. Maria Salazar: The Need for a Pragmatic Immigration Fix (10 min) Learn more about your ad choices. Visit megaphone.fm/adchoices

Send us a textEnglish-IELTS Word of the Day: [Pragmatic]Unlock your English potential with our daily IELTS vocabulary series!

Tell us what you think of the show! This Week in Cleantech is a weekly podcast covering the most impactful stories in clean energy and climate in 15 minutes or less featuring Paul Gerke of Factor This and Tigercomm's Mike Casey. This week's episode features special guest David Roberts, host of the Volts podcast, who recently sat down with clean-energy analyst Michael Liebreich to discuss calls for a “climate reset” that emphasizes costly technologies over proven clean energy solutions. This week's "Cleantechers of the Week" are:Andrew Otazo who has hauled more than 17 tons of trash, mostly from the islands around Biscayne Bay. Otazo wants to clear as much trash as he can. Forrest Smith, former chief petroleum engineer for the National Park Service. Forrest was the only individual responsible for cleaning up dozens of abandoned oil and gas wells at national parks across the country. Last month, he was forced to step down and the NPS is not looking to replace him. Juan Naula. Juan struggled to find funding for his ride-sharing startup, so he quit his job to pick up trash on the streets of L.A. Juan started a social media account titled, “Clean L.A. With Me,” and started a nonprofit to raise money and recruit volunteers to help him.This Week in Cleantech — November 07, 2025How virtual power plants could meet data centre energy demand — The Financial TimesWhite House Fossil Fuel Bet Is Losing to Green Energy — BloombergSlow rollout throttled Biden's big clean energy ambitions, former staffers say — POLITICO$615,000 a Day: Order to Keep Coal Plant Open Ignites Debate in Michigan — The Wall Street JournalMichael Liebreich on a "pragmatic climate reset" – VoltsWant to make a suggestion for This Week in Cleantech? Nominate the stories that caught your eye each week by emailing Paul.Gerke@clarionevents.com

This episode dives deep with Benny Fergusson, a foundational member of the show, about his journey from marketing to a career focused on connection, particularly with the body. Benny recounts how his early experiences with marketing highlighted a disconnect from himself, leading him to explore inner connection. He emphasizes that true wants come from within, citing the example of herbs like ashwagandha that foster inner connection.   Benny's current work, the Neurosomatic School, is all about understanding the body and its relationship to life. He shares his personal struggles with spinal issues in his 20s, which forced him to slow down and reconnect. He critiques externalized views of the body, like those in sports, where the body is seen as a tool for tasks rather than a source of inner wisdom.   The conversation touches on the modern world's approach to bodywork, with Mason noting the proliferation of practices like weights, yoga, and meditation to keep society from "breaking." Benny introduces his "SAFE" acronym for cultivating awareness: See, Allow, Feel, Embody. He explains that true healing isn't about fixing something broken, but about allowing what is, and creating the environmental circumstances to support the body's natural healing process. He challenges the idea of "letting go" as an act of doing, emphasizing the need to develop internal reference points for states like relaxation.   Benny also discusses the importance of integrating practice into daily life, rather than separating it as a form of escapism or spiritual ego. He advocates for exploring the full spectrum of human experience, from love to hate, to truly embody qualities. He highlights the interrelationship of things in the body, using knee pain as an example where the focus should be on supporting structures like the ankle and hip, rather than just the knee itself.   The discussion then shifts to the Neurosomatic School's approach for practitioners, focusing on bringing humanity back to health and addressing the "wounded healer" dynamic. Benny stresses the importance of personal embodiment for practitioners, as you can only guide others where you've been yourself. He outlines the school's four pillars: connection, breathing, mobility, and cultivation, emphasizing a pragmatic, individualized approach rather than a "one-size-fits-all" methodology. He aims to develop "all-terrain vehicle practitioners" who can adapt their tools to different contexts and individual needs.   Key takeaways from Benny and Mason: [00:00:37] Internal Connection as a Foundation   [00:04:43] Holistic Body Understanding   [00:17:57] Interconnectedness of the Body   [00:17:57] Pragmatic and Individualized Methodology   [00:23:47] The "SAFE" Framework for Awareness   [00:38:02] Integrating Practice into Daily Life   [00:41:48] Practitioner Embodiment and Humanity  Call to Action Alright, so we've just ripped into a deep chat with Benny Fergusson, one of the OG members of the show, about ditching the external hustle and getting real about internal connection. If you're being honest with yourself and you're tired of just throwing bodywork at a problem to keep from 'breaking,' this is your next, essential step.   The Neurosomatic School isn't just theory; it's the pragmatic, individualized approach that moves beyond the spiritual ego and 'unembodied advice.' It's time to truly apply the SAFE Framework and embrace the messy spectrum of human experience. Remember, as Benny says, you can only guide others where you've been yourself.   Dive into the four core pillars: Connection, Breathing, Mobility, and Cultivation. This work is about building real, internal reference points and developing those "all-terrain vehicle" skills.   Ready to get out of the superficial and start living the work? Don't just listen to the wisdom—go embody it.

China's AI rollout diverges sharply from the US, favoring open-source models and broad adoption over high-cost infrastructure. China's top tech firms including Tencent, Baidu and Alibaba will invest less than 10% of the $370 billion that US hyperscalers plan to spend on AI capex this year. This cost-conscious approach aligns with Beijing's AI Plus strategy, aiming to embed AI across all sectors by 2027 to boost productivity. Who will win the AI race? And are we in a bubble in AI infrastructure spending? Robert Lea, senior tech analyst at Bloomberg Intelligence, joins John to discuss why China's broader economy, rather than its tech companies, may be the main beneficiary of the nation's AI rollout.See omnystudio.com/listener for privacy information.

Reagan's Pragmatic Cold War Victory, Don Regan's Disastrous Tenure, and the Iran-Contra Near-Death Experience. Max Boot discusses how Ronald Reagan had no patience for communism, and in his first term, his policy toward the Soviet Union was somewhat unsuccessful, though it improved in 1985 with the ascension of Mikhail Gorbachev. Reagan's genius was recognizing that Gorbachev was a different communist leader he could "do business with," and they established a rapport that allowed them to constructively reduce nuclear armaments and peacefully end the Cold War. The transition into Reagan's second term saw a catastrophic personnel decision when Reagan allowed Jim Baker and Don Regan to swap jobs. Regan lacked political instincts and presided over problems that culminated in the Iran-Contra scandal. Reagan was highly exercised by American hostages seized by Hezbollah, and National Security Advisor Bud McFarlane suggested shipping weapons to supposed Iranian moderates in exchange for hostage releases, which was a fiasco. The scandal intensified when McFarlane's successor, John Poindexter, and Oliver North diverted the profits from the weapon sales to fund the anti-communist Contras in Nicaragua. This incident could have led to impeachment, but Reagan's salvation was his reputation for being hands-off and disengaged. Reagan also faced criticism over a human rights double standard, speaking eloquently about violations behind the Iron Curtain but being less exercised about apartheid in South Africa.

Fresh out of the studio and we hit our 500th episode milestone, guest host Yana Fry from Yana TV turns the tables on Bernard Leong, CEO of Dorje AI and host of Analyse Asia, in a special ask-me-anything format. We start with Bernard's journey from finding his first guest to navigating 11 years of podcasting, revealing his 12-word life philosophy: "Learn from everyone, follow no one, observe the patterns, work like hell." Following on, Bernard shares how his theoretical physics background provides the tools on everything from digital transformation to building Dorje AI's vision of reimagining ERP systems. The conversation dives deep into Bernard's pragmatic idealist worldview, product management philosophy and focus on the future. Bernard announces a major rebrand: Analyse Asia is dropping "Asia" to become the Analyse Podcast as it expands to a global audience, marking a new chapter in the show's evolution."For Dorje AI, what great looks like is being able to solve the ERP problem for businesses. It could take five years, ten years, or even two decades — because every technology adoption cycle takes time. We're at the beginning of a massive shift, but many still cling to the old ways of doing things. The one thing I've learned about digital transformation is this: everyone loves transformation, but they hate to change. Everything that people say will happen in two years usually takes five.When I think about Analyse Asia, greatness for me is being able to do an interview without looking at a set of questions — to tease out a guest's story authentically, without prejudice, without being a fanboy. Just getting the story out. If I can do that, that's great. Of course, hitting a million subscribers would be fantastic — that's the next milestone I'm chasing. But for me, it's always: ‘I've reached this milestone — what's next?'When you think about frugality at the highest level, it's not about resources — it's about time. The real measure is how much time you can spend doing what truly matters. That's what great looks like for me: asking, what's the minimum amount of time I can make the maximum impact? Maybe I'll never fully get there. But if we can say we lived this life without regret — that's enough." - Bernard LeongEpisode Highlights:[00:00] Quote of the Day by Bernard Leong[01:00] Introduction: Yana Fry (Guest Host) and Bernard Leong[02:05] Early Days of Analyse Asia Finding first guest was biggest initial challenge[04:30] Looking at Everything from a corporate executive like a theoretical physicist[06:23] Podcast interviews are combinations of science and art[08:19] Pragmatic idealist philosophy shapes Bernard's worldview[10:17] 12 Word Advice: Learn from Everyone, Follow No One, Observe the Patterns & Work like Hell[13:00] Dorje AI solving fundamental ERP ledger problems[16:15] Attacking competitors' strongest strength - Lessons of history from Kublai Khan[21:34] New is Easy and Right is Hard for Product Management[24:00] Audio to video was hardest podcast pivot[29:25] Japanese craftsman approach keeps Bernard going[33:09] Analyse Asia rebranding to Analyse Podcast globally[39:55] Father's 50-year loyalty shaped Bernard's management philosophy[44:00] Asia is diverse cities, not monolithic continent[46:00] Most problems aren't AI problems after questioning[51:00] What does Great Look Like for Dorje AI, Analyse Asia and Bernard Leong?[52:10] ClosingProfile: - Bernard Leong, Host of Analyse Asia Podcast, CEO of Dorje AI https://dorje.ai, Adjunct Associate Professor from NUS Business School & Institute of Systems Science. - Guest Host: Yana Fry from  @yanatvsg  which we highly recommend and subscribe to: https://www.youtube.com/@yanatvsgLinkedIn: https://www.linkedin.com/in/yanafry/Podcast Information: Bernard Leong hosts and produces the show. The proper credits for the intro and end music are "Energetic Sports Drive." G. Thomas Craig mixed and edited the episode in both video and audio format.

Join us on a transformative journey through the Bhagavad Gita as we explore the profound wisdom of transcending delusion. In this enlightening podcast, we delve into the teachings of Lord Krishna, who guides Arjuna on the path to spiritual liberation by overcoming the confusion and attachments that bind us to material existence.Discover the key to attaining a steadfast intellect, known as Stithaprajnya, and learn how to navigate the dense forest of delusion, or Moha Kalilam. Krishna's teachings in verses 2.51-2.54 illuminate the path of Buddhi Yoga, emphasizing detachment from the fruits of our actions as a way to rise above desires and achieve clarity. By aligning with Krishna's divine wisdom, we can cultivate equanimity (samatvam) and steady our intellect to transcend life's distractions.Through the insights of renowned spiritual masters like Swami Vivekananda and Adi Shankaracharya, we explore the importance of transcending delusion in the pursuit of spiritual growth. Practical guidance is offered on how to perform duties without attachment, cultivate clarity, and develop unwavering wisdom.This episode also addresses Arjuna's poignant question about recognizing a Stithaprajnya, one who has transcended delusion and achieved a steady state of wisdom. Krishna explains that true spiritual attainment resides within and cannot be judged by external appearances. Drawing inspiration from examples like Ramana Maharshi, we highlight how inner transformation is the essence of spiritual growth.Join us on this illuminating journey as we unravel the transformative power of Krishna's timeless teachings. Discover how to break free from the cycles of confusion and attachment and embark on the path to spiritual liberation. With Krishna as your guide, learn how to achieve inner peace and steadfast wisdom through the practices of Karma Yoga, detachment, and surrender.Tune in now and take the first step toward overcoming the illusions that bind you, as we unlock the secrets to attaining clarity, equanimity, and liberation through the profound teachings of the Bhagavad Gita.krsnadaasa (Servant of Krishna)Full transcript can be found here: Chapter 2: Transcending Delusion: Sankhya Yoga: Shlokas 51 to 54 - Pragmatic Bhagavad Gita

Stephanie C. DeMasi, MD, joins CHEST® Journal Podcast Moderator, Matt Siuba, DO, MS, to discuss her research comparing neurologic outcomes between lower and higher oxygen saturation targets following cardiac arrest.  DOI: 10.1016/j.chest.2025.04.027 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

Lately, everyone from Tony Blair to Daniel Yergin is calling for a “climate reset,” so I brought on clean-energy analyst Michael Liebreich to discuss his own, very different version. While others push expensive distractions, Liebreich argues that the inexorable growth of cheap renewables is already on track to displace fossil fuels, a “tortoise” strategy that will win without the need for crisis politics. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.volts.wtf/subscribe

Dr. Geo speaks with cancer immunologist Matthew Halpert, PhD about Immunocine, a dendritic-cell platform that “double-loads” patient-specific tumor signals to trigger a strong, physiologic immune response. Discussion includes mechanism, prostate cancer cases, how it can complement ADT and focal radiation, eligibility, workflow, and access.Chapters00:00 How the Immune System Fights Prostate Cancer02:00 Why dendritic cells matter; generals vs NK/T “soldiers”07:00 The “double-loading” breakthrough and fail-safe concept14:00 Trials in difficult cancers; safety and early signals18:00 Prostate cases: CRPC responses; lesions regressing22:00 Combining with ADT and focal radiation; timing27:00 Critical need for viable tissue; preservation tips34:00 Patient journey: review → tissue + apheresis → 3 doses/6 weeks41:00 Peri-lymphatic delivery; what patients feel; follow-up/boosts49:00 Cost, access, insurance help; foundations; closing takeawaysKey TakeawaysDendritic cells orchestrate immunity; NK/T cells execute.Precision double-loading overcomes a built-in fail-safe to amplify activation.Tissue access and preservation are essential for a broad, personalized target set.Pragmatic combination care: ADT and selective radiation can create a therapeutic window and enhance antigen presentation.________________________

Send us a textWe sit down with Drs. Paul Freeman and Nick Jeffery to discuss a treatment for down dogs that's changing outcomes and conversations: percutaneous intradiscal chondroitinase injections that act like chemical fenestration, reduce extruded disc material, and help non-ambulatory dogs recover without opening the spine.We walk through the origin of the idea, the ethical hurdles, and the growing dataset behind safety and effectiveness. You'll hear why deep pain–positive dogs with acute disc injuries often do as well with enzyme injections as with decompressive surgery, and how careful case selection can minimize risk. We get practical about inclusion criteria—currently focused on dogs under 15 kg, with French Bulldogs now included under close monitoring—and the technical realities of needle placement, imaging guidance, and when to add MRI. We also dig into the strategy of treating three to five disc levels to lower recurrence, and why this multi-level approach could outperform single-site surgery over the long term.The conversation doesn't dodge the hard calls. We compare large compressive lesions versus primarily contusive injuries, discuss when early surgery still makes sense, and share early experiences expanding to cervical cases with ultrasound and fluoroscopic checks. Looking ahead, we explore research priorities: defining time windows for chronic presentations, tracking recurrence across breeds, and building the evidence to place chondroitinase correctly in the treatment pathway. We even touch on how AI could one day use imaging data to predict which dogs need urgent decompression and which can safely recover with enzyme-first care.If you're an ER vet, GP, or neurologist looking to offer owners real choices, this is a grounded, data-informed guide to a less invasive option that can preserve mobility and reduce euthanasia driven by cost. Listen, share with your team, and help more “down dogs” stand again. Subscribe, leave a review, and tell us: where would you place chondroitinase in your spinal care protocol?JAVMA article: https://doi.org/10.2460/javma.24.12.0790INTERESTED IN SUBMITTING YOUR MANUSCRIPT TO JAVMA ® OR AJVR ® ? JAVMA ® : https://avma.org/JAVMAAuthors AJVR ® : https://avma.org/AJVRAuthorsFOLLOW US:JAVMA ® : Facebook: Journal of the American Veterinary Medical Association - JAVMA | Facebook Instagram: JAVMA (@avma_javma) • Instagram photos and videos Twitter: JAVMA (@AVMAJAVMA) / Twitter AJVR ® : Facebook: American Journal of Veterinary Research - AJVR | Facebook Instagram: AJVR (@ajvroa) • Instagram photos and videos Twitter: AJVR (@AJVROA) / Twitter JAVMA ® and AJVR ® LinkedIn: https://linkedin.com/company/avma-journals

This is the full episode of The Morning Show with Preston Scott for  Wednesday, October 22nd.Our guests today include:- Tom Clavin- L.G. Jay Collins Follow the show on Twitter @TMSPrestonScott. Check out Preston's latest blog by going to wflafm.com/preston. Listen live to Preston from 6 – 9 a.m. ET and 5 – 8 a.m. CT!WFLA Tallahassee Live stream: https://ihr.fm/3huZWYeWFLA Panama City Live stream: https://ihr.fm/34oufeR Follow WFLA Tallahassee on Twitter @WFLAFM and WFLA Panama City @wflapanamacity and like us on Facebook at @wflafm and @WFLAPanamaCity.      

The message from Rome is clear: You can still buy certainty, but it'll cost more. Italy's flat tax overhaul is less about politics and more about arithmetic.View the full article here.Subscribe to the IMI Daily newsletter here. 

This summer, Michael Liebreich wrote two essays under the title of the Pragmatic Climate Reset. The first challenged the idea that the clean energy transition has failed. And the second challenged the clean energy and climate community to a reset, exploring eight areas which he thinks the transition has gone astray.In this special episode, Bryony Worthington sits down with Michael Liebreich, to unpack Part 2 of “The Pragmatic Climate Reset.”Michael lays out a bold vision for cutting through the noise — replacing ideology with realism, and paralysis with progress. From net zero targets and critical minerals to global politics, energy security, and the economics of clean tech, this is a conversation about what it takes to deliver a just and workable climate transition.Bryony asks Michael,Why criticise Greta Thunberg rather than call out anti-climate commentators like Joe Rogan or President Trump?Did he go too easy on the fossil fuel industry?What does he think he got wrong?How has the essay been received, and did he get any good feedback, either positive or negative.Michael puts forward the idea that if the transition is to succeed in the long run and keep the public on board, we must proceed as a tortoise, not a hare, building on the considerable momentum of renewables to phase fossil fuels out of our energy mix while also keeping energy affordable, and everyone's lights on.Listen now, or watch the full episode on YouTube.Leadership Circle:Cleaning Up is supported by the Leadership Circle, and its founding members: Actis, Alcazar Energy, Davidson Kempner, EcoPragma Capital, EDP of Portugal, Eurelectric, the Gilardini Foundation, KKR, National Grid, Octopus Energy, Quadrature Climate Foundation, SDCL and Wärtsilä. For more information on the Leadership Circle, please visit https://www.cleaningup.live.Links and more:Read Part I here: https://about.bnef.com/insights/clean-energy/liebreich-the-pragmatic-climate-reset-part-i/Read Part 2, here: https://about.bnef.com/insights/clean-energy/liebreich-the-pragmatic-climate-reset-part-ii-a-provocation/Watch the first part of the pragmatic climate reset: https://www.youtube.com/watch?v=OHKGor2_BzQExplore all of Michael's audioblogs and essays: https://www.youtube.com/playlist?list=PLe8ZTD7dMaaAGobfBqd5eRQfeb5l9vPLG

 “If you can't afford a pet, you shouldn't own one.” Ever said this line?Once you've  been on the receiving of someone's anger about the cost of their vet bill, it's an easy thought to have. But it's not the whole story, is it?In this episode, I sit down with Dr. Paul Manktelow - a veterinary surgeon with 20+ years in UK animal charities and current Director of Veterinary Services at Blue Cross. Dr Paul shares lessons learned in not-for-profit vet care to help us untangle that tension between care, compassion, and commercial reality.We cover:Trends from the front lines in the charity sector How “affordability” is shifting under rising cost of livingDecision-making tools that balance optimal vs achievable careBusiness models that either enable or block access to careHow vets can approach financial conversations with clarity, dignity, and trustYou'll learn about:

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter David Allison is a world-renowned scientist and award-winning scientific writer who has spent more than two decades at the forefront of obesity research. In this episode, David joins for his third appearance on The Drive to bring clarity to one of the most contentious topics in modern nutrition—protein. He explores the historical pattern of demonizing macronutrients, the origins and limitations of the RDA for protein, and what the evidence really says about higher protein intake, muscle protein synthesis, and whether concerns about harm are supported by actual data. He also discusses the challenges of conducting rigorous nutrition studies, including the limits of epidemiology and crossover designs, as well as conflicts of interest in nutrition science and why transparency around data, methods, and logic matter more than funding sources. The episode closes with a discussion on processed and ultra-processed foods, the public health challenges of tackling obesity, and whether future solutions may depend more on drugs like GLP-1 agonists or broader societal changes. This is part one of a two-part deep dive on protein, setting the stage for next week's conversation with Rhonda Patrick. We discuss: The cyclical pattern of demonizing different macronutrients in nutrition and why protein has recently become the latest target of controversy [3:15]; The origin and limits of the protein RDA: from survival thresholds to modern optimization [6:30]; Trust vs. trustworthiness: why data, methods, and logic matter more than motives in science [13:30]; The challenges of nutrition science: methodological limits, emotional bias, and the path to honest progress [17:15]; Why the protein RDA is largely inadequate for most people, and the lack of human evidence that high protein intake is harmful [30:30]; Understanding the dose-response curve for muscle protein synthesis as protein intake increases [45:15]; Why nutrition trials are chronically underpowered due to weak economic incentives, and how this skews evidence quality and perceptions of conflict [48:15]; The limitations and biases of nutrition epidemiology, and the potential role of AI-assisted review to improve it [56:15]; The lack of compelling evidence of harm with higher protein intake, and why we should shift away from assuming danger [1:04:15]; Pragmatic targets for protein intake [1:09:30]; Defining processed and ultra-processed foods and whether they are inherently harmful [1:16:15]; The search for a guiding principle of what's healthy to eat: simple heuristics vs. judging foods by their molecular composition [1:25:00]; Why conventional public health interventions for obesity have largely failed [1:38:15]; Two ideas from David for addressing the metabolic health problem in society [1:42:30]; The potential of GLP-1 agonists to play a large role in public health [1:46:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Pragmatic. A man of action. Preacher and practicer. That's how one might describe the prophet Haggai. As our teacher Dr. McGee says, “Haggai doesn't have his head in the clouds, he gets right down to the nitty gritty, where the rubber meets the road.” Learn more about Haggai and his relationship to Zechariah and Malachi.

This interview was recorded for the GOTO Book Club.http://gotopia.tech/bookclubRead the full transcription of the interview here:https://gotopia.tech/episodes/383Pragmatic Dave Thomas - Pragmatic Programmer Turned PublisherSarah Taraporewalla - CTO APAC at ThoughtworksRESOURCESDavehttps://pragdave.mehttps://twitter.com/pragdavehttps://github.com/pragdavehttps://linkedin.com/in/dave-thomas-53aa1057Sarahhttps://sarahtaraporewalla.comhttps://twitter.com/sarahtaraphttps://www.linkedin.com/in/sarahtaraporewallahttps://github.com/staraporfLinkshttps://pragprog.comhttps://agilemanifesto.orgDESCRIPTIONSarah Taraporewalla (CTO APAC at Thoughtworks) sits down with programming legend Dave Thomas—co-founder of The Pragmatic Programmer and co-creator of principles like DRY (Don't Repeat Yourself)—to discuss his latest book "Simplicity."Dave reveals why he believes "Agile is Dead" and shares his disillusionment with how agile practices have become rigid, corporate processes rather than the flexible, value-driven approach originally envisioned in the Agile Manifesto he helped create. The conversation centers around his new Orient-Step-Learn framework, designed to help individual developers master true simplicity through deliberate practice and feedback loops, emphasizing that real simplicity requires mastery and cannot be achieved overnight.Dave advocates for developers to take personal agency, reduce unnecessary dependencies, and focus on what they can control rather than waiting for organizational change, arguing that simplicity is ultimately about cutting away complexity to reveal elegant, minimal solutions.RECOMMENDED BOOKSDave Thomas • simplicity • https://amzn.to/43FghBJDave Thomas & Andy Hunt • The Pragmatic Programmer • https://amzn.to/43QuMBjDave Snowden & Friends • Cynefin • https://amzn.to/3FSnF3Inspiring Tech Leaders - The Technology PodcastInterviews with Tech Leaders and insights on the latest emerging technology trends.Listen on: Apple Podcasts SpotifyBlueskyTwitterInstagramLinkedInFacebookCHANNEL MEMBERSHIP BONUSJoin this channel to get early access to videos & other perks:https://www.youtube.com/channel/UCs_tLP3AiwYKwdUHpltJPuA/joinLooking for a unique learning experience?Attend the next GOTO conference near you! Get your ticket: gotopia.techSUBSCRIBE TO OUR YOUTUBE CHANNEL - new videos posted daily!

What does it mean to be pragmatic about AI adoption, while staying true to the values and mission driving people and organizations? When Elisa Lindinger decided to talk about AI, her intention was to say what she had to say once, and then move on with her life without having anyone ask about AI ever again. The plan backfired heavily, but somehow, that turned into a good thing. Lindinger is the Co-founder of SUPERRR, an independent non-profit organization. SUPERRR was created to serve the thesis is that digital policy is social policy, and it needs bold visions and feminist values. Like most other individuals and organizations today, Lindinger's inbox has been flooded with new invitations every day. Invitations to discuss AI, to facilitate workshops on feminist AI, or the inevitable coaching offer to finally learn how to prompt properly. This made Lindinger feel that other topics that are just as crucial are disappearing from the conversation. "AI and Unlikelihood" was an attempt to situate how the people at SUPERRR view the phenomenon of AI, and why they believe it's essential to return our attention to other topics as well. What happened instead was that SUPERRR's post got viral on LinkedIn, reigniting the topic of AI and stealing the limelight. An algorithmic glitch? Perhaps. But SUPERRR's stance of rejecting the narrative of blind adoption of generative AI resonated with many people. We met with Lindinger to explore the nuance behind what some might superficially call a Luddite approach, and to talk about setting priorities right, imagining futures people want to live in, and how to go From AI literacy to futures literacy. With cracks in the AI narrative beginning to show, the backdrop could not be more timely. Article published on Orchestrate all the Things: https://linkeddataorchestration.com/2025/10/02/pragmatic-ai-adoption-from-futurism-to-futuring/

Metaphysics and Faith: A reasonable approach to the Supernatural.

In this thought-provoking episode of Thinking Out Loud, Nathan Rittenhouse is joined by Pastor Mike Gehry of Communitas Church to explore the rising interest in Christianity—particularly among young adults—and the theological challenges and opportunities that come with it. Drawing from their seminary days and Mike's expertise in spiritual formation and direction, Nathan and Mike engage in a rich, biblically grounded discussion about pragmatic conversions, cultural Christianity, spiritual disciplines, and the dangers of reducing the Gospel to mere self-help. With insights into the tension between tradition and modern evangelicalism, this episode offers deep encouragement for Christians who crave substance, nuance, and clarity in their walk with Christ. Whether you're a pastor, church leader, or just someone seeking authentic spiritual growth, this conversation will challenge and inspire you to pursue Christlikeness through the power of the Holy Spirit, within the life of the Church, and grounded in Scripture.DONATE LINK: https://toltogether.com/donate BOOK A SPEAKER: https://toltogether.com/book-a-speakerJOIN TOL CONNECT: https://toltogether.com/tol-connect TOL Connect is an online forum where TOL listeners can continue the conversation begun on the podcast.

Pragmatic language is about more than just talking—it's the invisible set of social rules that help conversations flow and relationships grow. For children on the spectrum, these skills can be tricky, but they're also essential, especially as they move from elementary into middle school.In this episode of the Not Your Average Autism Mom podcast, Shannon explains what pragmatic language really means, why it matters so much, and how you can practice these skills at home. You'll walk away with practical strategies, everyday examples, and a new perspective on helping your child build confidence and connection—one conversation at a time. And if you missed it, Shannon was recently featured on News Nation Now with Nichole Berlie, ahead of the administration's autism announcement on September 22nd. She shares her perspective as a mom raising an autistic son and as the founder of Not Your Average Autism Mom. Every chance she gets to use her voice for families like ours is a privilege—and this conversation was no exception.

Michael Rosen on the linguistic comfort food of clichés, pragmatics and how we use language to connect us beyond the actual words used. Derek Bousfield explains how words do more than carry meaning: context governs what we say and how it's understood. Dr Bousfield is Reader in Pragmatics and Communication and Co-Director of The Manchester Centre for Research in Linguistics and co-author of Talking in Clichés: The Use of Stock Phrases in Discourse and Communication. Produced for BBC Audio Bristol by Beth O'Dea, in partnership with the Open University. Subscribe to the Word of Mouth podcast and never miss an episode: https://www.bbc.co.uk/sounds/brand/b006qtnz

Sam Matterface is alongside talkSPORT's Alex Crook and European football expert Kevin Hatchard to debrief the latest round of Premier League actionComing up: Pep channels his inner Mourinho at the Emirates, a huge win for Amorim over Chelsea, and Potter on borrowed time at West Ham Hosted on Acast. See acast.com/privacy for more information.

The election of Donald Trump to a second term as President marked a turning point in the politics of climate action – not just in the US, but around the world.The airwaves are suddenly awash with commentators, claiming that the transition has failed, that it was always a fool's errand, and that we must resign ourselves to a fossil-based future forever.The narratives of failure all revel in pointing out that we have not seen dramatic cuts in fossil fuel use globally, consistent with keeping the temperature increase to 1.5C, and are not on track to achieve global net zero by 2050.The climate and clean energy community is facing a choice. It can remain reactive, doubling down on old narratives, pressing on with existing policies, preaching to the converted and watching the pace of change slow for the next few years.Or it can undertake what I call a Pragmatic Climate Reset: Wind back historical over-reach, accept harsh realities, address legitimate concerns, refresh its offer and find new ways of communicating with a confused public.Leadership Circle:Cleaning Up is supported by the Leadership Circle, and its founding members: Actis, Alcazar Energy, Davidson Kempner, EcoPragma Capital, EDP of Portugal, Eurelectric, the Gilardini Foundation, KKR, National Grid, Octopus Energy, Quadrature Climate Foundation, SDCL and Wärtsilä. For more information on the Leadership Circle, please visit https://www.cleaningup.live.Links and more:• Read the full article on BNEF: https://about.bnef.com/insights/clean-energy/liebreich-the-pragmatic-climate-reset-part-ii-a-provocation/• Watch the first part of the pragmatic climate reset: https://www.youtube.com/watch?v=OHKGor2_BzQ

In this episode of CAREER-VIEW MIRROR, we're celebrating the career to date of Richard Savoie.Richard is the co-founder and CEO of Adiona, which uses AI to power millions of efficient, lowest-carbon deliveries around the world for brands such as Coca-Cola and Amazon. He's a sought-after speaker and thought leader on transport, mobility, and AI.His career has taken him from New Hampshire to Boston, and eventually to Sydney, Australia, through roles at EMC, Smiths Medical, and Medtronic. Along the way, he's gained experience across engineering, medical devices, and entrepreneurship — building resilience, adaptability, and the insight to eventually launch his own business in sustainable technology.In our conversation, we talk about Richard's early years in Nashua, New Hampshire, where family challenges and early responsibilities shaped his determination. He shares how severe asthma inspired him first toward medicine, then pivoted him into engineering after falling in love with physics.We follow his path through Northeastern University, internships with Panametrics and EMC, and his transition into medical devices with Smiths Medical and Covidien. He reflects on career setbacks during the financial crisis, lessons from mentors, and the importance of empathy and relationships in leadership.We also talk about his relocation to Australia, his experience running a small medical device company, and the difficult decision to leave after equity disagreements — a setback that ultimately led him into entrepreneurship. Richard describes how Adiona's optimisation technology, developed through a partnership with Coca-Cola, delivered dramatic reductions in emissions and on-road time, and how branding, support structures, and resilience are critical to startup success.Connect with RichardLinkedIn:  https://www.linkedin.com/in/richsavoie/Website: https://www.adionatech.com/About AndyI'm a business leader, coach, and the creator of the Fulfilling Performance framework—designed to help people bring more of themselves to what they do and experience greater fulfilment and performance as a result.Over the past 25+ years, I've led and developed businesses including Alphabet UK, BMW Financial Services in the UK, Singapore, and New Zealand, and Tesla Financial Services UK. Alongside this, I've coached individuals and facilitated leadership development programmes in 17 countries across Asia, Europe, and North America.In 2016, I founded Aquilae to support leaders and teams in the mobility sector and beyond. Through workshops, coaching, and peer mentoring, we enable high performance that's also fulfilling—for individuals, teams, and organisations.Learn more about Fulfilling PerformanceCheck out Release the Handbrake! The Fulfilling Performance HubConnect with AndyLinkedIn: Andy FollowsEmail: cvm@aquilae.co.ukJoin a peer mentoring team: Aquilae AcademyThank you to our sponsors:ASKE ConsultingEmail: hello@askeconsulting.co.ukAquilaeEmail: cvm@aquilae.co.ukEpisode Directory on Instagram @careerviewmirror  If you enjoy listening to our guests career stories, please follow CAREER-VIEW MIRROR in your podcast app. Episode recorded on 09 September, 2025.

On this episode of the Chuck ToddCast, Chuck sits down with Brian Bengs, who challenged John Thune in South Dakota and is running for senate as an independent, and Todd Achilles, an independent from Idaho, to explore what it really means to run outside the two-party system. They open up about why they chose independence, the challenges of campaigning in red states where the word “Democrat” is a nonstarter, and the dysfunction they see as the product of both parties. From tariffs hurting farmers to the growing cost of attention in politics, the conversation highlights how America's political and economic systems reward division and extremism over pragmatism and compromise.The discussion also tackles the bigger picture: whether the Republican Party could split between MAGA and traditional conservatives, why democracy no longer serves as a pressure release valve, and how corporate power and money in politics further erode trust. Bengs and Achilles share lessons from Ross Perot's run, their views on immigration reform, and the importance of building bipartisan relationships in an age where the middle is punished. For them, independence isn't just about rejecting partisanship—it's about offering voters an alternative path forward in a system that too often feels broken.Got injured in an accident? You could be one click away from a claim worth millions. Just visit https://www.forthepeople.com/TODDCAST to start your claim now with Morgan & Morgan without leaving your couch. Remember, it's free unless you win!Timeline:(Timestamps may vary based on advertisements)00:00 Brian Bengs & Todd Achilles join the Chuck ToddCast01:30 Why are you running and why as an independent?02:45 Someone needed to challenge John Thune in SD03:45 Voters in red states hear “Democrat” and tune out despite agreement05:00 We have huge levels of debt, division and dysfunction06:00 70% of Idahoans identify as independent06:45 Democrats haven't provided a counter message in red states09:00 Will the MAGA and traditional wings of the Republican party split?10:45 Trump's tariffs hurting farmers, can they be won over?12:15 Republican leaders get in trouble for “not being MAGA enough”13:30 Tariffs and market concentration are squeezing farmers15:30 What does “caucusing on your own” look like?17:30 Deny both parties a majority and independents are swing votes18:15 Is Thune's leadership an impediment to your candidacy? 19:15 The status quo dysfunction is a product of both parties20:30 The information ecosystem punishes the middle & incrementalism22:15 Attention is incredibly expensive for candidates23:45 The attentional incentive structures reward extremism 25:30 The importance of meeting voters in person26:30 How did we get to the point where political violence isn't shocking? 27:30 Democracy is supposed to be a pressure release valve, but it isn't working28:30 Talking to the voter who prioritizes economics over democracy29:45 We need to fix democracy to fix other issues30:45 There's a “race to blame” in wake of Kirk shooting32:00 Corporations are pushing their operation costs onto taxpayers33:30 Guardrails on the private sector have been chipped away at35:00 The Big Beautiful Bill will shutter rural hospitals37:15 How can we make money in politics a salient voting issue?39:00 Lessons that can be learned from Ross Perot's run?41:30 Pragmatic immigration requires border security and path to citizenship43:45 Congress more worried about their own security than deescalation44:45 The importance of building bipartisan relationships46:45 What 2 senators would you most look forward to working with if elected48:00 Favorite Democratic and Republican president?49:45 Eisenhower was the closest to an independent of any modern president50:30 Military service doesn't lend itself to partisanship Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

On this episode of the Chuck ToddCast, Chuck explores the frustrations of the “mainstream middle” in red states and why Democrats can't seem to reach them, even as discontent with the country grows. From the poisonous information ecosystem that radicalizes voters to the outsized influence of social media and big tech money in Washington, the conversation digs into how extremism thrives while moderation is punished. Chuck also examines the rise of independents, the possibility of a third-party shake-up, and how redistricting battles in California, Missouri, and Georgia could reshape the political map. With major races in New Jersey and Virginia looming, and Democrats struggling to find the right message, the episode highlights both the dangers and the opportunities in an increasingly unsettled political landscape.Then, Chuck sits down with Brian Bengs, who challenged John Thune in South Dakota and is running for senate as an independent, and Todd Achilles, an independent from Idaho, to explore what it really means to run outside the two-party system. They open up about why they chose independence, the challenges of campaigning in red states where the word “Democrat” is a nonstarter, and the dysfunction they see as the product of both parties. From tariffs hurting farmers to the growing cost of attention in politics, the conversation highlights how America's political and economic systems reward division and extremism over pragmatism and compromise.The discussion also tackles the bigger picture: whether the Republican Party could split between MAGA and traditional conservatives, why democracy no longer serves as a pressure release valve, and how corporate power and money in politics further erode trust. Bengs and Achilles share lessons from Ross Perot's run, their views on immigration reform, and the importance of building bipartisan relationships in an age where the middle is punished. For them, independence isn't just about rejecting partisanship—it's about offering voters an alternative path forward in a system that too often feels broken.Finally, Chuck gives his ToddCast Top 5 states that could elect an independent candidate to the U.S. Senate and answers listeners' questions in the “Ask Chuck” segment.Got injured in an accident? You could be one click away from a claim worth millions. Just visit https://www.forthepeople.com/TODDCAST to start your claim now with Morgan & Morgan without leaving your couch. Remember, it's free unless you win!Timeline:(Timestamps may vary based on advertisements)00:00 Introduction02:00 There is a mainstream middle in red states, but Dems can't reach them03:00 Feeling terrible about the state of the country, don't see a path out04:30 We have a poisonous information ecosystem that radicalizes people05:15 Social media is poisoning the well, but big tech doesn't shoulder blame06:30 When algorithms curate content, it makes the platform a publisher 08:00 Public schools finally starting to ban phones in classrooms09:00 The phones are toxic for adults too, not just kids11:00 Big tech companies have saturated D.C. with money to avoid regulation13:00 The administration is speaking in the language of the red scare13:45 Bipartisanship hasn't been good for Donald Trump14:30 The fastest growing political party is “no party”15:45 The two major parties need a time out in order to course correct16:45 Spencer Cox can't succeed in MAGA, but would be a great leader18:00 A third party scare could sober up the two major parties19:45 The one commonality between the parties is internet radicalization21:30 We need a moderate temperament to lead the country22:45 Our information ecosystem punishes moderation25:00 It could be a tough year for incumbents26:45 The big redistricting fight brewing in California28:00 There are 3 big money entities trying to get CA voters to vote no28:45 California voters are educated and want the redraw to be temporary30:00 Missouri redistricting law could go before voters and be repealed31:30 California Democrats have been very organized33:00 Democrats' messaging problem over redistricting35:00 The Georgia Democratic primary for governor is fascinating37:15 GA governor primary could be bellwether for progressive vs moderate38:00 Big money pouring into NJ and Virginia races39:30 Virginia AG race will show whether law & order politics will be effective41:45 Trump conceding the NYC mayor's race to Mamdani42:45 Jeffries in a tough spot, can't be seen embracing a socialist 45:45 Brian Bengs & Todd Achilles join the Chuck ToddCast 47:15 Why are you running and why as an independent? 48:30 Someone needed to challenge John Thune in SD 49:30 Voters in red states hear "Democrat" and tune out despite agreement 50:45 We have huge levels of debt, division and dysfunction 51:45 70% of Idahoans identify as independent 52:30 Democrats haven't provided a counter message in red states 54:45 Will the MAGA and traditional wings of the Republican party split? 56:30 Trump's tariffs hurting farmers, can they be won over? 58:00 Republican leaders get in trouble for "not being MAGA enough" 59:15 Tariffs and market concentration are squeezing farmers 1:01:15 What does "caucusing on your own" look like? 1:03:15 Deny both parties a majority and independents are swing votes 1:04:00 Is Thune's leadership an impediment to your candidacy? 1:05:00 The status quo dysfunction is a product of both parties 1:06:15 The information ecosystem punishes the middle & incrementalism 1:08:00 Attention is incredibly expensive for candidates 1:09:30 The attentional incentive structures reward extremism 1:11:15 The importance of meeting voters in person 1:12:15 How did we get to the point where political violence isn't shocking? 1:13:15 Democracy is supposed to be a pressure release valve, but it isn't working 1:14:15 Talking to the voter who prioritizes economics over democracy 1:15:30 We need to fix democracy to fix other issues 1:16:30 There's a "race to blame" in wake of Kirk shooting 1:17:45 Corporations are pushing their operation costs onto taxpayers 1:19:15 Guardrails on the private sector have been chipped away at 1:20:45 The Big Beautiful Bill will shutter rural hospitals 1:23:00 How can we make money in politics a salient voting issue? 1:24:45 Lessons that can be learned from Ross Perot's run? 1:27:15 Pragmatic immigration requires border security and path to citizenship 1:29:30 Congress more worried about their own security than deescalation 1:30:30 The importance of building bipartisan relationships 1:32:30 What 2 senators would you most look forward to working with if elected 1:33:45 Favorite Democratic and Republican president? 1:35:30 Eisenhower was the closest to an independent of any modern president 1:36:15 Military service doesn't lend itself to partisanship1:39:00 ToddCast Top 5 states most likely to elect an independent to the senate 1:40:15 #1 & #2 - Vermont & Alaska 1:41:15 #3 Minnesota 1:42:45 #4 Arizona 1:43:30 #5 Florida 1:45:00 Runner ups 1:46:15 Ask Chuck 1:46:30 Is it possible for a candidate to run as a uniter in the current climate? 1:51:30 At congressional hearings, are the subjects provided questions in advance? 1:54:15 The importance of presenting multiple viewpoints in a fractured ecosystem 1:57:45 Instances of a political death being used to attack other side so soon? 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Pablos Holman is a hacker and inventor and the author of Deep Future: Creating Technology that Matters, the indispensable guide to deep tech. Previously, Pablos worked on spaceships at Blue Origin and helped build The Intellectual Ventures Lab to invent a wide variety of breakthroughs. Pablos also hosts the Deep Future Podcast and is managing partner at Deep Future.This episode is brought to you by:Cresset prestigious family office for CEOs, founders, and entrepreneurs: https://cressetcapital.com/timMaui Nui Venison​, delicious, nutrient-dense, and responsible red meat: https://mauinuivenison.com/lp/timAG1 all-in-one nutritional supplement: https://drinkag1.com/timTimestamps:00:00 Intro02:12 The hacker mindset33:05 Nuclear52:35 Autonomous ships58:48 Pragmatic optimism01:00:29 Risk tolerance01:04:50 Blue Origin01:11:59 Zero Effect philosophy01:34:43 China01:43:07 Taiwan01:45:04 AI01:50:42 Salsa02:08:44 Deep tech investing*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Bulletproof Dental Podcast Episode 407 HOSTS: Dr. Peter Boulden and Dr. Craig Spodak DESCRIPTION In this episode of the Bulletproof Dental Practice Podcast,  Craig and Peter celebrate Craig's birthday while delving into the importance of team dynamics and relationships in the dental business. They discuss the common misconceptions about needing the right team to succeed and emphasize that great people are created through effective leadership. The conversation explores the challenges of managing a dental practice, the significance of time and freedom, and the realities of selling a practice to a DSO. They provide pragmatic steps for overwhelmed dentists looking to improve their business and work-life balance.  TAKEAWAYS The importance of celebrating milestones in life and business. Great people in business are created, not just found. Building strong relationships is key to business success. Leadership growth is crucial for organizational success. Managing the urgent versus the quiet important tasks is essential. More money does not equate to more freedom. Understanding the value of time is critical for dentists. The DSO model can be misleading for practice owners. Creating a business that works for you is vital for long-term success. Pragmatic steps can help overwhelmed dentists regain control of their practices. Maximizing productivity can be achieved with a three-day work week. Clarity in goals is essential for success. Reverse engineering helps in creating actionable plans. Effective communication aligns the team with the vision. Delegation empowers team members and fosters growth. Dentists need to adopt a business mindset for freedom. Clarity reduces confusion and enhances team performance. Your dental license is a valuable asset for business. CHAPTERS 00:00 Celebrating Milestones: Craig's Birthday Episode 01:05 The Importance of Team Dynamics in Dentistry 03:15 Building Relationships: The Key to Business Success 06:40 Navigating the Challenges of Business Management 10:09 Understanding the Value of Time and Freedom 12:34 The Evolution of a Dentist's Career 14:03 The DSO Dilemma: Selling Your Practice 17:05 The Financial Realities of Selling a Dental Practice 18:50 Pragmatic Steps for Overwhelmed Dentists 21:15 Creating a Business That Works for You 25:00 Maximizing Productivity: The Three-Day Work Week 27:59 Clarity and Reverse Engineering Your Goals 28:56 Communicating Vision: Aligning Your Team 31:57 Working on Your Business: Strategy and Innovation 36:02 The Importance of Clarity in Leadership 39:58 Delegation: Empowering Your Team for Growth 43:57 Creating a Business Mindset in Dentistry  

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Mark Laurence and I had a great discussion on AI and the future and A.icehouse, a new initiative for SMEs that he is working on with Icehouse, to learn more about the future of AI and what it might mean for companies and directors and business owners as well as charities and other organisations.  Have a look at these links to find out more.   A.icehouse website: https://www.theicehouse.co.nz/a.icehouse   Ten Past Tomorrow site: https://www.tenpasttomorrow.com  Icehouse: https://www.theicehouse.co.nz  For more episodes visit www.theseeds.nz  More on A.icehouse: "You don't need to master every new app, platform or update. You need practical and pragmatic AI knowledge that powers your business to navigate the evolution AI is asking of you. AI is moving faster than leaders can follow. It can feel overwhelming, noisy, and hard to know what really matters. A.icehouse is designed to give Kiwi SME owners and senior teams clarity, in practical and tangible ways. No hype. No waffle. We focus on AI literacy and skills first, then layer in the tools so you can build the confidence to make better informed decisions. Back in 2000, Icehouse helped SMEs make sense of the internet and the knowledge era. Today, with applied AI expertise from Ten Past Tomorrow, we're helping businesses make sense of AI and the intelligence era. In A.icehouse you'll find: Plain-English explanations and demonstrations to build AI literacy around what AI is, what it isn't, and how it is reshaping business models and industries, right now. Practical AI skill training, so you yourselves become powerful users of frontier AI tools to drive radical and immediate efficiency and productivity in your own roles. Pragmatic strategies and maps so you can drive the same AI-powered efficiency and productivity as mentioned above, throughout your entire organisation Time-respectful sessions designed for busy leaders. Honest conversations about unknowns and trade-offs, not hype or silver bullets. A mix of formats, from quick webinars, online courses, to live in-person in-depth symposiums; so you can choose what fits your time and needs. A trusted partnership: Icehouse's 20+ years of SME support with Ten Past Tomorrow's applied AI excellence."

Segment 1: • Methodist preacher goes viral for endorsing divorce in the name of “authentic self.” • This message twists God's Word and moves the goalposts on covenant. • Jesus gave narrow reasons for divorce—yet culture demands limitless excuses. Segment 2: • The preacher doubles down—arguing against God's design for marriage. • His message: don't stay in marriages that “aren't working.” • Marriage pictures Christ and His Church—God is not pleased with false preaching. Segment 3: • Thousands claimed “saved,” but the gospel wasn't preached. • A watered-down message reflects seeker-sensitive culture. • The stakes are eternal—souls are lost when the full gospel is missing. Segment 4: • China unveils the first pregnancy humanoid—praised by many. • Pragmatic arguments ignore reality: robots aren't image-bearers of God. • With AI poised to replace jobs, what happens to human purpose and economics? ___ Thanks for listening! Wretched Radio would not be possible without the financial support of our Gospel Partners. If you would like to support Wretched Radio we would be extremely grateful. VISIT https://fortisinstitute.org/donate/ If you are already a Gospel Partner we couldn't be more thankful for you if we tried!

Ace Wizards Arroai the Pragmatic and N'erevine Livolias travel the country to find old, neglected dungeons and restore them to their former glory! Today, they arrive in Lake Town, home to the wizard tower of Xalatan the Triumphant. But before they can start renovating, they need to embark on the greatest adventure of all: getting buy-in from local stakeholders!! CREDITS: Max Knightley as Arroai the Pragmatic Iris Christianson as N'erevine Livolias Molly Rhinebeck as Sevette Passan Lexi Waltner as Olin Bootman MUSIC BY MAX KNIGHTLEY EDITED BY MAX KNIGHTLEY AND CRYSTAL ZASLAVCHIK CONTENT WARNING: This episode contains fireworks sounds.

Season 15 of the Knowing Faith podcast begins on August 21st! In this episode, Jen Wilkin, JT English, and Kyle Worley give you a preview of what is to come in Season 15.Questions Covered in This Episode:What are some of our main disagreements?What is our goal?What are we talking about this season?Resources Mentioned in this Episode:Romans 9-11 Follow Us:Twitter | Instagram | Facebook | WebsiteOur Sister Podcast:Tiny TheologiansSupport Training the Church and Become a Patron:patreon.com/trainingthechurchYou can now receive your first seminary class for FREE from Midwestern Seminary after completing Lifeway's Deep Discipleship curriculum, featuring JT, Jen and Kyle. Learn more at mbts.edu/deepdiscipleship.To learn more about our sponsors please visit our sponsor page.Editing and support by The Good Podcast Co.

The 2025 generative AI image market is a trade-off between aesthetic quality, instruction-following, and user control. This episode analyzes the key platforms, comparing Midjourney's artistic output against the superior text generation and prompt adherence of GPT-4o and Imagen 4, the commercial safety of Adobe Firefly, and the total customization of Stable Diffusion. Links Notes and resources at ocdevel.com/mlg/mla-25 Try a walking desk - stay healthy & sharp while you learn & code Build the future of multi-agent software with AGNTCY. The State of the Market The market is split by three core philosophies: The "Artist" (Midjourney): Prioritizes aesthetic excellence and cinematic output, sacrificing precise user control and instruction following. The "Collaborator" (GPT-4o, Imagen 4): Extensions of LLMs that excel at conversational co-creation, complex instruction following, and integration into productivity workflows. The "Sovereign Toolkit" (Stable Diffusion): An open-source engine offering users unparalleled control, customization, and privacy in exchange for technical engagement. Table 1: 2025 Generative AI Image Tool At-a-Glance Comparison Tool Parent Company Access Method(s) Pricing Core Strength Best For Midjourney v7 Midjourney, Inc. Web App, Discord Subscription Artistic Aesthetics & Photorealism Fine Art, Concept Design, Stylized Visuals GPT-4o OpenAI ChatGPT, API Freemium/Sub Conversational Control & Instruction Following Marketing Materials, UI/UX Mockups, Logos Google Imagen 4 Google Gemini, Workspace, Vertex AI Freemium/Sub Ecosystem Integration & Speed Business Presentations, Educational Content Stable Diffusion 3 Stability AI Local Install, Web UIs, API Open Source Ultimate Customization & Control Developers, Power Users, Bespoke Workflows Adobe Firefly Adobe Creative Cloud Apps, Web App Subscription Commercial Safety & Workflow Integration Professional Designers, Agencies, Enterprise Core Platforms Midjourney v7: Premium choice for artistic quality. Features: Web UI with Draft Mode, user personalization, emerging video/3D. Weaknesses: Poor text generation, poor prompt adherence, public images on cheap plans, no API/bans automation. OpenAI GPT-4o: An intelligent co-creator for controlled generation. Features: Conversational refinement, superior text rendering, understands uploaded image context. Weaknesses: Slower than competitors, generates one image at a time, strict content filters. Google Imagen 4: Pragmatic tool focused on speed and ecosystem integration. Features: High-quality photorealism, fast generation, strong text rendering, multilingual. Weaknesses: Less artistic flair; value is dependent on Google ecosystem investment. Stable Diffusion 3: Open-source engine for maximum user control. Features: MMDiT architecture improves prompt/text handling, scalable models, vast ecosystem (LoRAs/ControlNet). Weaknesses: Steep learning curve, quality is user-dependent. Adobe Firefly: Focused on commercial safety and professional workflow integration. Features: Trained on Adobe Stock for legal indemnity, Generative Fill/Expand tools. Weaknesses: Creative range limited by training data, requires Adobe subscription/credits. Tools and Concepts In-painting: Modifying a masked area inside an image. Out-painting: Extending an image beyond its original borders. LoRA (Low-Rank Adaptation): A small file that applies a fine-tuned style, character, or concept to a base model. ControlNet: Uses a reference image (e.g., pose, sketch) to enforce the composition, structure, or pose of the output. A1111 vs. ComfyUI: Two main UIs for Stable Diffusion. A1111 is a beginner-friendly tabbed interface; ComfyUI is a node-based interface for complex, efficient, and automated workflows. Workflows "Best of Both Worlds": Generate aesthetic base images in Midjourney, then composite, edit, and add text with precision in Photoshop/Firefly. Single-Ecosystem: Work entirely within Adobe Creative Cloud or Google Workspace for seamless integration, commercial safety (Adobe), and convenience (Google). "Build Your Own Factory": Use ComfyUI to build automated, multi-step pipelines for consistent character generation, advanced upscaling, and video. Decision Framework Choose by Goal: Fine Art/Concept Art: Midjourney. Logos/Ads with Text: GPT-4o, Google Imagen 4, or specialist Ideogram. Consistent Character in Specific Pose: Stable Diffusion with a Character LoRA and ControlNet (OpenPose). Editing/Expanding an Existing Photo: Adobe Photoshop with Firefly. Exclusion Rules: If you need legible text, exclude Midjourney. If you need absolute privacy or zero cost (post-hardware), Stable Diffusion is the only option. If you need guaranteed commercial legal safety, use Adobe Firefly. If you need an API for a product, use OpenAI or Google; automating Midjourney is a bannable offense.