Podcasts about Viro

MIllaiset ovat politiikan asetelmat eduskunnan aloittaessa kevätkautensa? Puhelimessa yliopistotutkija Jenni Karimäki Itä-Suomen yliopistosta. Yhdysvaltain presidentti Donald Trump on iskenyt silmänsä Grönlannin ja Ukrainan luonnonvaroihin. Millainen poliittinen ase luonnonvaroista on tulossa? Vieraana maailmanpolitiikan professori Teivo Teivainen Helsingin yliopistolta. Puhelimessa johtaja Hannu Lahtinen GTK:sta. Lähetyksessä kuullaan myös Ukrainan-toimittaja Justas Stasevskijin raportti. Viro ja muut Baltian maat irtautuvat viikonloppuna Venäjän ja Valko-Venäjän sähköverkosta. Virossa oleva toimittaja Rain Kooli ja Venäjän-kirjeenvaihtaja Heikki Heiskanen kertovat, kuinka isosta operaatiosta on kyse. EK esittää, että hallituksen pitäisi tehdä selvitykset Turusta Tukholmaan rakennettavasta tunnelista ja sillasta, Helsingistä Tallinnaan rakennettavasta tunnelista ja Vaasasta Uumajaan rakennettavasta tunnelista tai sillasta. Millaisia vaatimuksia huoltovarmuus asettaa Suomessa liikenteen infrastruktuurille? Keskustelemassa johtava asiantuntja Tiina Haapasalo Elinkeinoelämän keskusliitosta, väylä- ja liikennetekniikan professori Pekka Leviäkangas Oulun yliopistosta ja logistiikkajohtaja Pekka Rajala Väylävirastosta. Juontajana Mira Stenström, toimittajana Justus Laitinen, tuottajana Annette Blencowe.

A United Nations report from late October has criticised France for their crackdown on protestors in New Caledonia earlier this year. Wire Host Caeden spoke to Viro Xulue, a Kanak advocate in New Caledonia, about the report and the continued movement for independence. They started by asking about what the report said.

En este episodio, nos adentramos en los detalles esenciales que a menudo se pasan por alto al momento de evaluar una propiedad. Más allá de la ubicación o el precio, conversamos sobre esos "puntos ciegos" que los compradores y arrendatarios suelen ignorar y que pueden marcar una gran diferencia en una inversión. Con una mirada honesta y práctica, compartimos nuestras propias experiencias y te guiamos a través de los aspectos cruciales que debes tener en cuenta al visitar y analizar un inmueble. Este es un episodio indispensable para quienes buscan tomar decisiones informadas y evitar sorpresas en la compra o alquiler de una propiedad residencial.

Goddess Reverie of Viro Playspace is this week's guest on Adult Site Broker Talk. Goddess Reverie performs on ViRo Playspace, an adult haptics-driven VR social space. She is powered by ViRo Live Studio, the only software to integrate body tracking, haptic teledildonics, and cam site API, allowing anyone on Earth to perform as an adult virtual avatar. She is a real live person who streams with an avatar using motion capture. The company developed several tools to handle her body tracking, facial tracking, voice capture, cam site integration, and many adult haptic toys so she can interact with her audience. The company wants to make her style of live-streaming accessible to anyone interested in trying it out, which is why they packaged those in-house tools into what is now ViRo Live Studio. Adult Site Broker is the most experienced company to broker adult sites. They've sold and helped people buy more xxx sites than any other broker. Adult Site Broker is the leading company to sell porn sites and buy porn sites. They help their clients work out equitable deals. Check out their brand-new website at www.adultsitebroker.com, the leading destination to broker porn sites. Adult Site Broker also has an affiliate program, ASB Cash, at https://asbcash.com, where you can earn 20% referring people to buy adult sites and sell adult sites to Adult Site Broker, the porn website broker. For more information, please visit us at www.adultsitebroker.com to help you broker adult sites. Listen to Goddess Reverie of Viro Playspace on Adult Site Broker Talk, starting today at www.adultsitebrokertalk.com

Food Friday--Viro's Italian Bakery! Bruce Ash, Chris, and YOU discuss what we're streaming on television.

Highlights this week. Interviews may be abbreviated. For the date and hour podcast to hear more, see the note (0:00) Dr. JoAnn di Filippo [Sept 30, Hr 2] (8:40) Joe DeSimone [Sept 30, Hr 3] (22:20) Grover Norquist previews the VP debate [Oct 1, Hr 2] (40:24) Tucson Councilman says policing is an extra that you need to increase taxes for [Oct 1, Hr 3] (46:57) Chris, Carlos Ruiz, and Matt discuss bare nalgas at a street takeover [Oct 2, Hr 3] (49:25) VP debate recap [Oct 2, Hr 1] (1:00:32) Carlos Ruiz with the Job Creators Network [Oct 2, Hr 3] (1:09:07) US Rep David Schweikert [Oct 3, Hr 2] (1:16:29) Southern Arizona Red Cross Exec Director Courtney Slanaker--how you can help the hurricane victims [Oct 3, Hr 3] (1:22:44) Viro's Italian Bakery [Oct 4, Hr 2] (1:28:40) Ted Maxwell and Sergio Mendez discuss RTA (excerpt of full discussion) [Oct 4, Hr 3]

En el episodio 89 de "Espacio Diseño", Michelle Urtecho y Rosángela Viro se unen a Massiel Sánchez y Rosario Rivas, las jóvenes creadoras del podcast "Más que Diseño", para una conversación intergeneracional sobre el mundo del diseño de interiores. Esta conversación no solo explora la pasión que las une, sino también las diferencias y aprendizajes que surgen de sus distintas trayectorias profesionales.En un tono íntimo y realista, comparten experiencias sobre lo que significa ser diseñadora en diferentes etapas de la vida y cómo el camino de cada una, aunque diferente, está marcado por momentos comunes de crecimiento, retos y evolución. Este episodio es una celebración de la conexión entre generaciones y un recordatorio de que, más allá del diseño, lo que verdaderamente importa es el aprendizaje mutuo y la inspiración compartida.Sumérgete en una conversación cercana, llena de empatía y sabiduría entre dos generaciones de diseñadoras apasionadas.

En este episodio Michelle Urtecho y Rosángela Viro invitan a Frinette Torres, madre de Michelle, para compartir una charla profundamente personal y artística. Frinette, además de ser gran gestora empresarial, es una talentosa artista cuya obra refleja su sensibilidad y conexión con el alma.Este episodio es un viaje hacia el proceso creativo de Frinette, quien combina la investigación artística con la experimentación técnica. Desde el óleo tradicional hasta obras abstractas en madera, su arte es una expresión pura de sus emociones y su pasión. Junto a su hija Michelle, exploran el poder de decirle "sí" a los deseos más profundos del ser, y cómo el arte se convierte en un reflejo de la propia vida.Conéctate con esta historia de amor, creatividad y profunda presencia.

En este episodio  tuvimos el honor de recibir al Sr. Angelo Viro, un empresario que no solo ha dejado su huella en la República Dominicana con su empresa Cerarte, sino que también ha sido un ejemplo de perseverancia, trabajo constante  y fe para su hija, Rosángela Viro, quien lo invita a este episodio junto a Michelle Urtecho. Juntos, nos regalan una conversación emotiva sobre cómo los valores fundamentales—como el trabajo incansable, el amor por la familia y la fe en Dios—han sido los pilares que han guiado el camino del Sr. Angelo en el competitivo mundo de los acabados y terminaciones para la arquitectura.Esta historia no solo refleja el éxito de un inmigrante italiano que encontró su destino en tierras dominicanas, sino que además es una poderosa lección sobre cómo el crecimiento en la industria del diseño es posible cuando se combina una visión de vida íntegra con pasión por el trabajo.Para todos los diseñadores y arquitectos que buscan inspiración, este episodio es un legado vivo.

Miércoles 4 de septiembre.Energía.Viro con energía gracias a lo divino en mí. Gustavo Alberto

¿Has imaginado qué super poder elegirías si pudieras tener uno? En este episodio, Rosángela y Michelle nos invitan a una conversación fresca y divertida, alejándose del contenido habitual. En esta charla espontánea, nos muestran un lado más personal, revelando sueños y risas que buscan conectar con la audiencia en un nivel más cercano. Este episodio es una oportunidad para conocerlas desde una perspectiva diferente y disfrutar de la química que las caracteriza.

Valtiovarainministeriön budjettiesityksestä ja syksyn työmarkkinanäkymistä keskustelemassa SAK:n pääekonomisti Ilkka Kaukoranta ja EK:n pääekonomisti Penna Urrila. Matkustaminen Venäjälle Viron kautta vaikeutuu entisestään: Viro aloittaa tänään täydet tullitarkastukset. Narvan rajanylityspaikalta raportoi Rain Kooli. Merihanhen ja kanadanhanhen metsästys alkaa pelloilta huomenna. Aikaistetulla metsästyksellä halutaan estää hanhiparvien aiheuttamia viljelyvahinkoja ja mahdollistaa riistavaran hyödyntäminen. Metsästyskauden alkamisesta kertoo Riistakeskuksen vs. riistapäällikkö Jörgen Hermansson. Syksyn tautitilanne: mikä kaataa työikäisiä petiin. Studiossa HUS:n infektioylilääkäri Asko Järvinen ja THL:n tartuntatautilääkäri Aino Nyqvist. Juontaja Atte Uusinoka, toimittajat Roosa Kajander, Seppo Kivimäki ja Mikko Haapanen. Tuottaja Anna-Maria Haarala.

¿Alguna vez has deseado llevar tu negocio de diseño al siguiente nivel mientras mantienes la creatividad y la libertad que te inspiraron a emprender? En este episodio, exploramos cómo lograrlo con la ayuda de un acompañamiento especializado.  En esta ocasión, Rosángela Viro, co-anfitriona del podcast, diseñadora de interiores, coach organizacional certificada y empresaria del mundo del diseño, nos habla sobre los beneficios de contar con un proceso de acompañamiento especializado para moverte desde tu estado actual hacia tu estado deseado.  Descubre cómo puedes prosperar en tu negocio de diseño y vivir conectado al disfrute, la creatividad y la libertad.

En este episodio, nos sumergimos en una conversación llena de anécdotas, risas y reflexiones espontáneas. Queremos conectar contigo de una manera relajada y cercana, compartiendo las historias y experiencias que han marcado parte de nuestro recorrido en conjunto en el mundo del diseño.Este episodio refleja nuestras charlas habituales: menos estructuradas, más genuinas y cargadas de momentos memorables.   En esta ocasión, queremos compartir  contenido más ligero y real, conectando contigo de una forma auténtica y espontánea.Únete a nosotras para revivir memorias llenas de risas, aprendizajes y experiencias que han sido parte de nuestras trayectorias como diseñadoras. 

¿ Buscas inspiración y perspectivas valiosas sobre el camino hacia el éxito en el diseño?  En este episodio compartimos reflexiones profundas sobre nuestra trayectoria profesional.  En esta ocasión  Rosángela Viro diseñadora de interiores y coanfitriona del podcast, comparte  su trayectoria profesional. Desde sus inicios hasta los desafíos y vivencias que ha enfrentado, su filosofía de vida y trabajo, así como su actual papel como mentora de diseñadores, interioristas y arquitectos, guiándolos hacia el éxito en sus negocios de diseño.Esta conversación íntima y abierta ofrece un espacio de confianza y libre expresión, permitiéndonos conocer más a fondo la vida de Rosángela. Descubre cómo superó obstáculos y limitaciones de juventud para transformarlos en una carrera de grandes logros.

Miten Gazaa hallitseva terroristijärjestö Hamas vastasi Israelin uuteen tulitaukoehdotukseen? Haastattelussa Suomen Lähi-idän instituutin säätiön tutkija Antti Tarvainen. EU-vaalit lähestyvät. Millaista valtaa mepit käyttävät ja mitä parlamentin toiminnasta olisi hyvä ymmärtää? Studiovieraina Ulkopoliittisen instituutin Euroopan unioni-tutkimusohjelman ohjelmajohtaja Juha Jokela ja Helsingin yliopiston Eurooppa-tutkimuksen keskuksen professori Johanna Kantola. Viro on Venäjän hyökkäyssodan alkamisen jälkeen järjestelmällisesti karkottanut maasta Venäjä-mielisiä aktivisteja, vaikka nämä olisivat asuneet maassa pitkäänkin. Toimittaja Rain Koolin raportti Tallinnasta. Venäjän epäillään häiritsevän laajasti gps-signaaleja. Häirintä on vaikuttanut viime aikoina erityisesti Finnairin lentoihin Tarttoon. Miten ilmailun turvallisuus taataan? Haastateltavina tutkimusjohtaja Martti Lehto Jyväskylän yliopistosta ja johtaja Jari Pöntinen Traficomista. EU:n maatalousministerit kokoustivat maanantai-iltana Luxemburgissa. Hellittävätkö Ukrainan viljaan kohdistuvat rajoitukset viimein? Kokouksen antia ruotii tutkimusprofessori Jyrki Niemi Luonnonvarakeskuksesta. Juontajana Mira Stenström. Toimittajina Veera Sinervo ja Anssi Väisänen, tuottajana Marija Skara.

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¡Hola a todos nuestros queridos oyentes de Espacio Diseño!  Estamos súper emocionadas porque marcamos el inicio de una nueva etapa en nuestro podcast. Después de más de un año al aire, sentimos que era el momento perfecto para evolucionar y llevar nuestra experiencia a un nuevo nivel.En este episodio, queremos compartir con ustedes todos los detalles de esta transformación. Hablaremos sobre el proceso que vivimos, los cambios que implementamos y cómo queremos que se sienta y viva la experiencia del podcast a partir de ahora.Fue un proceso emocionante y desafiante, pero estamos seguras de que valió la pena. Queríamos asegurarnos de que cada cambio estuviera alineado con nuestra visión para el futuro de Espacio Diseño y cómo queremos conectarnos con ustedes, nuestra increíble audiencia.Así que los invitamos a que nos acompañen en este viaje de evolución y crecimiento. Compartiremos las pautas que trazamos para nuestro futuro juntos y cómo estamos emocionadas de continuar creando contenido que inspire y motive a todos ustedes.Gracias por su paciencia y por sintonizarnos una vez más. ¡Estamos felices de embarcarnos en esta nueva etapa con todos ustedes.

Food Friday! Viro's Italian Bakery. Vito Jr. brings in lots of treats, previewing tomorrow's Wake Up Tucson brunch Happy Hour. Check them out, Broadway and Sarnoff. Bakery, cafe, gelato, deli meats. Movies with Mark! Top Italian-American movies not involving the mob

Jenna Viron Tuhkimoleikkaus on vaikuttava, häiritsevä ja vaivaamaan jäävä viihdyttävä kokeellinen kirja, jota olen viimeisen puolen vuoden ajan suositellut eniten muille. Tänään oli kunnia päästä keskustelemaan Arkikullan studiolla itse tekijän kanssa kirjasta, kokeellisesta taiteesta, kauneudesta ja muistakin oleellisista asioista. Kiitos Jenna vierailusta! Tuhkimoleikkaus: https://www.kosmoskirjat.fi/kirjat/tuhkimoleikkaus-kovakantinen-kirja/ Kuva: Meri Björn --- Takakansi-podcast --- Some ja www: Instagram: https://instagram.com/takakansipodcast Facebook: https://facebook.com/takakansipodcast Takakansi.fi https://takakansi.fi Tuottaja Marko Suomi: https://instagram.com/markosuomi https://twitter.com/markosuomi https://linkedin.com/in/markosuomi Tunnusmusiikki: Bucket - No More Than Human https://bucketpunk.bandcamp.com/album/always-chasing-greener-grass https://www.instagram.com/bucketpunks/

US Representative David Schweikert. NDAA vote, Colorado diqualifies Trump from ballot, public debt is equal to GDP. Vito Croce Sr. and Vito Jr. from Viro's Italian Bakery and CJ Hamm from Saguaro Corners Restaurant join Chris. Check out virosbakery.com for hours and location. Bakery, meats, cafe. Your sweet and savory favorites! 22nd St and Sarnoff.

Notkahtaneet Pisa-tulokset ovat huolettaneet tällä viikolla useassa länsimaassa. Lähes kaikissa OECD-maissa tulokset heikkenivät neljän vuoden takaisesta. Etelänaapurimme Viro näyttää pärjäävän Euroopassa parhaiten. Erityisesti virolaiset pojat oppivat koulussa paremmin kuin suomalaiset. Ohjelmassa käydään Virossa selvittämässä, mihin perustuu Viron koulujen nousu. Lisäksi kuullaan raportti Britanniasta, jossa oppimistulosten heikentymistä pidetään koronapandemian koulusulkujen syynä. Lopuksi tavataan Suomessa vieraillut YK:n erityisraportoija, jolla on rauhoittelevia sanoja Pisa-tutkimuksesta. Maailmanpolitiikan arkipäivää -ohjelman ovat toimittaneet Kirsi Crowley, Jani Parkkari ja Paula Vilén. Äänitarkkailijana on Matias Puumala. Kuva: Tuuli Laukkanen/Yle.

En este episodio exploramos la fascinante conexión entre la moda y el diseño, descubriendo cómo la moda se convierte en una fuente de inspiración para propuestas creativas y experiencias llenas de emociones. Analizamos cómo la moda no solo establece tendencias actuales, sino que también sirve como un rico depósito de estilos pasados. Exploramos cómo esta disciplina influye en diversas industrias, desde la fabricación hasta los acabados, texturas y pinturas, inspirándonos a transmitir mensajes y proponer nuevas perspectivas en nuestras creaciones. Únete a nosotras en este episodio para aprender de nuestra perspectiva de cómo encontrar inspiración en el apasionante mundo de la moda.This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

En esta ocasión repetimos concepto de episodio, se trata de una conversación espontánea donde compartimos con ustedes contenido profesional y personal del cual solemos conversar entre nosotras y que en esta oportunidad quisimos que ustedes también sean parte.Esperamos que este contenido les dé una visión de cómo nos encontramos actualmente viviendo nuestro último trimestre del año y qué cosas estamos realizando para culminar el mismo en orden, claridad y enfoque.Deseamos que este episodio pueda serles útil y a la vez les brinde una mirada alternativa de cómo podrías prepararte para un cierre de ciclo.This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

Nick Arbuckle, Founder and CEO of Viro, a revolutionary platform that mitigates the effects of global climate change by tracking the positive impact of your … Read more The post Building a Future of Climate Actions that Get Rewarded appeared first on Top Entrepreneurs Podcast | Enterprise Podcast Network.

En esta entrega, tus anfitrionas Michelle Urtecho y Rosángela Viro, ambas diseñadoras de interiores, te invitamos a nuestra honesta conversación del cliente ideal.Juntas exploramos las características clave que definen a este cliente utópico y compartimos nuestras reflexiones sobre el por qué detrás de cada una de ellas. A través de divertidas anécdotas, revelamos experiencias gratificantes y desafiantes con clientes, brindando una visión auténtica y sincera sobre lo que realmente importa para nosotras en una colaboración exitosa.Prepárate para reírte y sentirte identificado con las reacciones espontáneas y comentarios reveladores que surgieron en esta conversación. Si eres amante del diseño de interiores o simplemente buscas “insights” valiosos sobre cómo encontrar el cliente ideal, ¡este episodio es para ti!This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

En el episodio 44 de Espacio Diseño, compartimos abiertamente algunos desafíos que hemos enfrentado al presentar nuestras propuestas de diseño.A través de anécdotas reveladoras, exploramos situaciones vividas y destacamos cómo hemos evolucionado para afrontarlas con confianza a lo largo del tiempo. Este episodio no solo ofrece un vistazo entre bastidores de nuestras experiencias, sino que también les brindará una valiosa oportunidad de identificación, permitiéndoles descubrir si han vivido situaciones similares en el emocionante mundo del diseño.¡No te lo pierdas!This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

¡Bienvenidos a un nuevo episodio de Espacio diseño! Hoy tenemos un programa muy especial, titulado "¿Te ha pasado...?", donde Rosángela Viro y Michelle Urtecho, tus anfitrionas, compartimos algunas de nuestras vivencias en una dinámica divertida y cercana.En este episodio, decidimos abrir nuestras experiencias profesionales para que conozcan un poco más sobre nosotras como interioristas. Queríamos que se sintieran parte de la conversación, como si estuvieran sentados con nosotras tomando un café y compartiendo anécdotas del mundo del diseño de interiores.La razón por la que creemos que este episodio vale mucho la pena escucharlo es porque en él nos mostramos auténticas y transparentes, sin filtros. Compartimos tanto nuestros éxitos como los desafíos que hemos enfrentado en nuestra carrera, y cómo hemos aprendido a superarlos.A lo largo de la dinámica, no solo nos reímos y nos divertimos compartiendo historias curiosas, sino que también ofrecimos consejos prácticos que pueden aplicar en su propia trayectoria profesional en el mundo del diseño. Nuestra intención es inspirar a todos aquellos que estén interesados en este campo y deseen conocer cómo enfrentamos situaciones diversas en nuestro día a día.Esperamos que se sientan identificados con algunas de nuestras vivencias y que, a través de nuestras experiencias, puedan aprender y crecer como profesionales. ¡Así que no te lo pierdas! Te aseguramos que será una conversación espontánea y enriquecedora llena de valiosas lecciones para el mundo del diseño de interiores. This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

Hour two of the 1000 hours podcast takes a look at the first widely known and studied African-American wrestling star: Viro "Black Sam" Small. Viro Small was born into slavery in South Carolina. After being freed following the Civil War, he traveled north and became a wrestling champion and well known boxer. He survived being shot in the neck but what happened afterward has been lost to history. Plus, some discussion about one of the most important pioneer wrestling stars: William Muldoon. In order to get an hour 3 of 1000 hours we need a new Patreon supporter at any level or a cash donation via the front page of WhenItWasCool.com to either Patreon or CashApp in the next 72 hours. As soon as it is received I will produce hour three.

En este episodio de Espacio Diseño, exploramos el fascinante mundo de la decoración monocromática. Descubre cómo crear diseños monocromáticos sin caer en lo aburrido y lograr espacios visualmente cautivadores. Este episodio te brinda las claves para lograr diseños monocromáticos vibrantes y llenos de vida.This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

Somos Michelle Urtecho y Rosángela Viro, las conductoras de Espacio Diseño, y en nuestro último episodio decidimos hacer algo diferente. Queríamos compartir con ustedes una conversación íntima y espontánea, esas que solemos tener entre nosotras, pero esta vez la hicimos pública para que también formen parte de ella.Nos hicimos preguntas mutuamente, sin saber de antemano qué nos íbamos a preguntar. Fue emocionante y un poco aterrador al mismo tiempo, ya que nos adentramos en aspectos de nuestras vidas y personalidades que tal vez no habíamos explorado en profundidad antes.Nos sorprendimos al descubrir cosas nuevas sobre la otra. Preguntas que parecían sencillas, pero que nos llevaron a reflexionar y revelar partes de nosotros mismos que quizás no compartimos regularmente en el podcast. Fue una oportunidad para conocernos aún más y profundizar en nuestra amistad y conexión como conductoras.Estamos emocionadas de compartir esta conversación especial con ustedes. Creemos que les dará una visión más completa de quiénes somos como personas y cómo esos aspectos de nuestras vidas se entrelazan con nuestro amor por el diseño.Si están interesados en conocer más a fondo a las conductoras de Espacio Diseño y descubrir cómo nuestras experiencias personales influyen en nuestra perspectiva sobre el mundo del diseño, los invitamos a sintonizar este episodio. Prepárense para una charla íntima y reveladora que les permitirá acercarse aún más a nosotras y comprender mejor nuestra pasión por este apasionante campo.¡Esperamos que disfruten de este episodio tanto como nosotras disfrutamos compartiéndolo con ustedes!This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

Interview with Robert W. Holloway, MD, and Sarfraz Ahmad, PhD, authors of Clinical Activity of Olvimulogene Nanivacirepvec–Primed Immunochemotherapy in Heavily Pretreated Patients With Platinum-Resistant or Platinum-Refractory Ovarian Cancer: The Nonrandomized Phase 2 VIRO-15 Clinical Trial. Hosted by Jack West, MD. Related Content: Clinical Activity of Olvimulogene Nanivacirepvec–Primed Immunochemotherapy in Heavily Pretreated Patients With Platinum-Resistant or Platinum-Refractory Ovarian Cancer

Interview with Robert W. Holloway, MD, and Sarfraz Ahmad, PhD, authors of Clinical Activity of Olvimulogene Nanivacirepvec–Primed Immunochemotherapy in Heavily Pretreated Patients With Platinum-Resistant or Platinum-Refractory Ovarian Cancer: The Nonrandomized Phase 2 VIRO-15 Clinical Trial. Hosted by Jack West, MD. Related Content: Clinical Activity of Olvimulogene Nanivacirepvec–Primed Immunochemotherapy in Heavily Pretreated Patients With Platinum-Resistant or Platinum-Refractory Ovarian Cancer

En este episodio descubrirás cómo lograr fotos espectaculares de tus espacios, un tema crucial para cualquier arquitecto, diseñador o decorador de interiores.Aprenderás secretos y trucos de estilismo utilizados por expertos para crear imágenes impresionantes de espacios interiores, desde elegir la iluminación adecuada hasta seleccionar los objetos y muebles correctos para cada toma.Te invitamos a que no te pierdas este episodio. Mejores la calidad de tus fotos y resalta tus habilidades como diseñador con nuestros consejos.This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

The guys sit down with Founder Nick Arbuckle on why he started Viro and his vision for this company! Remember to review and subscribe and connect with us on LinkedIn as well!

Bruce, the adult site broker, host of Adult Site Broker Talk and CEO of Adult Site Broker, the leading adult website broker, who is known as the company to sell adult sites, is pleased to welcome Vex Ruby and Shift D of Viro Live Studio to Adult Site Broker Talk. Vex Ruby and Shift-D of ViRo Live Studio are this week's guests on Adult Site Broker Talk. Vex Ruby is the world's most advanced virtual cam performer, and spokeswoman for ViRo Playspace, an adult haptics driven VR social space. Shift-D is the founder and creative director of ViRo Playspace and ViRo Live Studio. You can follow Vex on Twitter @vexxxruby and ViRo Playspace @ViRoPlayspace. Bruce, host of the show and CEO of Adult Site Broker said: “This was one of our most interesting podcasts. What Shift and Vex are doing over there is truly groundbreaking. I'm sure you'll enjoy it.” Adult Site Broker is the most experienced company to broker adult sites. They've sold and helped people buy more xxx sites than any other broker. Adult Site Broker is the leading company to sell porn sites and buy porn sites. They help their clients work out equitable deals. Check out their brand-new website at www.adultsitebroker.com, the leading destination to broker porn sites. Adult Site Broker also has an affiliate program, ASB Cash, at https://asbcash.com, where you can earn up to 20% referring people to buy adult sites and sell adult sites to Adult Site Broker, the porn website broker. And they are now offering a FREE marketplace for sellers with properties valued at less than their minimum listing amount of $50,000, www.asbmarketplace.com. For more information, please visit us at www.adultsitebroker.com to help you broker adult sites. Listen to Vex Ruby and Shift D of Viro Live Studio on Adult Site Broker Talk, starting today at www.adultsitebrokertalk.com

En este episodio Rosángela Viro y Michelle Urtecho conversan sobre la importancia de loscuartos de baños dentro de los espacios interiores.-¿Cómo ha evolucionado el concepto del baño al espacio que es hoy en día?Importancia de este espacio para el cuidado personal.Divertidas anécdotas dentro de estos espacios.¿Qué criterios de diseño tomar en cuenta a la hora de diseñar los baños?Accede al siguiente enlace para conocer las 7 tendencias actuales de diseño parainspirarte a crear BAÑOS CON ESTILO que Rosángela Viro comparte en un webinargratuito: https://www.nhapstudio.com/registro-webinar-banos-con-estiloThis show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

Viro tuomitsi Venäjän. Työnteko ja psyyke. Omistusasuminen. Säveltäjä Kari Tikka on kuollut. Auringonpimennys. Sää.

¿Cómo evitar la contaminación de ideas de otros para crear tu propio concepto auténtico de diseño? En este episodio te contaremos el proceso creativo de Rosángela Viro donde la creatividad conecta con cada fase de elaboración y presentación de la propuesta de diseño.This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

Venäjä yrittää paikata heikkoa sotamenestystään Ukrainassa Putinin määräämällä osittaisella liikekannallepanolla. Se on alkanut onnahdellen. Puolustusministeriön mukaan yli 200 000 miestä on kuitenkin mobilisoitu. Tosin samaan aikaan Venäjältä on paennut tätäkin enemmän ihmisiä. Ohjelmassa kuullaan kutsuntoja Armeniaan paenneita. Lisäksi selviää, miten Viro suhtautuu maassa olevien venäläisten mahdolliseen rintamalle lähtöön. Ohjelmassa pohditaan myös, miten liikekannallepano voi vaikuttaa Venäjän ydinaseisku-uhkaan Ukrainassa. Ohjelman toimittavat Heikki Heiskanen, Rain Kooli ja Paula Vilén. Äänitarkkailijana on Juha Sarkkinen.

En este episodio conversaremos sobre la historia detrás de Michelle Urtecho & Rosángela Viro y te contaremos y por qué queremos hablar de diseño.This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/5664376/advertisement

We're 3 years into Steve Yzerman's tenure as GM of the Detroit Red Wings, and it's time to take stock of the #Yzerplan. Tune in as we discuss The Athletic's NHL Front Office Confidence rankings, and whether Yzerman and the Detroit Red Wings ranking among the league's best is warranted, what Yzerman, Draper & Co. have done well & what hasn't worked out, & whether the Yzerplan is still on track (6:55). Also, we take a look at Detroit's prospects at the World Juniors, discussing Simon Edvinsson's less-than-stellar performance, Carter Mazur & Red Savage doing work for Team USA, Sebrango & Cossa winning with Canada, Viro, Wallinder, Niederbach, & more (27:30)! Of course, Mason McTavish's insane goal-line save leading to Kent Johnson's OT gold medal winner (46:00). Finally, a look at Nazem Kadri's huge contract with Calgary, Montreal taking on Monahan's contract in an insanely confusing deal (52:35), & so much more - enjoy!  Head over to wingedwheelpodcast.com to find all the ways to listen, how to support the show, and so much more. 

On Episode 104 of Taking the Pulse, we're joined by Dr. Nicholas Vafai, Founder and President of Viro Research. Dr. Vafai tells us about the innovative work he and his father, Dr. Abbas Vafai, are doing at their company, along with some of the unique challenges that come with the complex FDA approval process. Tune in!

Keskustelijoina ovat Juha itkonen, Anu Koivunen ja Taru Tujunen. Suoraa puhetta johtaa Pauli Aalto-Setälä. Onko aika kopioita jotain Virosta? Puheenjohtaja luettelee perusteluita: Lehdistönvapausindeksissä Viro meni Suomen ohi, sen BKT on kehittynyt enemmän kuin Suomen ja Pisa-tuloksissakin Viro oli parempi. Tujunen lisää, että ansaitsemme tulevan näpäytyksen: Viro aikoo ratifioida Suomen mahdollisen Nato-hakemuksen ensimmäisenä Nato-maana. Koivunen huomauttaa kuitenkin, että kansalaisyhteiskunnan ja hyvinvointivaltion rakentaminen jääneet Virossa Suomea vähemmälle. Juha Itkonen pohtii naisten maanpuolustustahtoa. Suomalaisten maanpuolustustahto on EVAn selvityksen mukaan kova: 73% miehistä ja naisista 36% on valmis puolustamaan maata aseellisesti. Ja 46–55-vuotiaista naisista jopa 48% on valmis tarttumaan aseeseen. Naisten luvut ovat Itkosen mukaan suuria. Anu Koivunen miettii kuntapäättäjien ja konsulttien suhdetta. – Onnea kotikaupunkini Kemi: ette lakkauttanut ensimmäisenä kaupunkina kaupunginteatteria! Itkonen paljastuu toiseksi Kemin tilanteen tuntijaksi, ja Tujunen puolestaan haluaisi nousta pöydälle ja lyödä kenkää pöytään kuntatalouden vuoksi. Taru Tujunen ei pysty hillitsemään itseään vaan katsoo jo kohti seuraavia eduskuntavaaleja. Hänestä taistelu käydään SDP:n ja Kokoomuksen kesken, ja suomalaiset tulevat palkitsemaan Kokoomusta Nato-kysymyksestä.

On this episode, Paige chats with the incredibly talented, kind and inspirational visual artist, mother and business owner, Isabel Seidel. Isabell is a German ex-pat living in Ourense, Spain where she creates vibrant contemporary landscapes.Isabell and Paige chat about how they became instant Instagram friends thanks to their mutual connections and friendships from Bri Custer's, Non Toxic Crit Group. Isabell shares her beautiful story of how she studies architecture but later switched to German and Spanish Philology and Pedagogy. Isabell shares her experience moving to Spain to teach German at Universidade de Viro. During her time teaching in Spain, she became very involved in the Urban Sketching community and started to organize her own sketch meet-up groups, teach watercolor and plein air painting workshops, and participate in outdoor speed painting competitions.Isabell share's her experience transitioning from teaching full time to becoming a full time artist and how her entrepreneurial husband, Victor has been such a supportive accountability partner throughout the whole process. Isabell expresses how Victor's "go-getting" attitude has helped her create unique opportunities for her art business. Paige and Isabell weave in and out of beautiful topics of conversation, such as being a self-taught painter, creating a set schedule and routine to create balance, productive/nurturing environments in the studio and at home, motherhood and what success means and looks like in both of their lives.To follow and support Isabell, check out https://isabellseidel.com and https://www.instagram.com/isabell.seidel

This week I'm thrilled to have Dr. Veronica Ruelas and Denise Gaffney as my guests to chat Forgiveness. Veronica and Denise are the co-founders of Forgivity, an app designed to foster a habit of forgiveness. To be fair, when I first heard about turning forgiveness into a habit, I was a bit hesitant. Forgiveness as a habit was nowhere near anything I would have considered. Throw on top of it a neuroscientific and psychological angle, and all of a sudden I'm becoming a big fan. I love the concept, especially in the context of the workplace. We touch on it in the podcast, but ultimately it should lead to a broader conversation of those “soft” words and terms (think vulnerability, psychological safety) that are vital to a functioning and more productive workplace culture. Ironically, these words we attribute as “soft” are embraced by the strongest and bravest leaders we know. They work. Beyond the workplace, there is an accountability aspect to forgiveness that I never gave much thought. It's a personal power to be able to forgive, and is one more notch on the belt of what we ultimately have control over. In fact, it's the lack of forgiveness that often prevents us from getting to where we need to go. Lots more to come on forgiveness – and one topic I encourage you to explore for yourself and your teams. Listen to the interview – they are fantastic – and learn how forgiveness just may be the buzzword that makes a significant difference for you this year. The Forgivity app is now available for download on iOS. For more information on the app, please visit www.forgivity.com. For more on Veronica and Denise, please hit up their channels: https://www.instagram.com/forgivity/ https://www.facebook.com/Forgivity https://www.tiktok.com/@forgivity Your Title Goes Here Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings. Click Here for an Unedited Transcript of the Podcast I'm Jim Frawley and this is bellwether. Welcome to bellwether. Thank you for being here this week. We have guests, multiple guests for the first time we're doing, you know, we've got a trio going here and it's gonna be very, very good. The topic is forgiveness, and I know it's, you know, it's forgiveness. We, we can all talk about forgive for some reason. It's one of the hottest words in corporate right now. I've gotten multiple phone calls about it right now. Everybody wants to know about how do you bring forgiveness into the workplace and what does that actually mean? Uh, which took me a little by surprise and, and very fortunately, almost, you know, as the world and universe can kind of work at the same time, I was introduced to these two wonderful individuals who have a solution for forgiveness in the workplace, and they have the app. Everything is an app, and this is, uh, this is going to be a very, very cool app. So I wanna talk to you about forgiveness. I'm gonna talk about the forgive app and let me introduce our wonderful guest this week. I'm gonna start with, we have Denise and Vero Vero. Please introduce yourself.Hi, I'm I'm Dr. Veronica OS and I'm the co-founder and co CEO of forg.And I'm Denise Kaney, I'm the other co-founder and co CEO of forg. Um, I have 20 years on wall street. I'm a certified, uh, energy leadership coach, and now I'm an entrepreneur,Which is a wonderful journey to be on. And when I think about wall street, I don't typically think of forgiveness unless you think about it in, you know, kind of government handouts, but we'll, we'll talk about, um, at, in a difficult corporate environment. Talk to me, we'll get it right out of the way. Yeah. Talk to me about the forgiving app, what it does and why you created it.So, um, it's, it's an, we use, uh, clinical neuroscience methods to, um, make forgiveness a more intuitive behavior because it's, it's not something we're, we're all taught that forgiveness is important and it's universal, but, uh, the, how is really missing from the equation. And so, um, yeah, so we, we infuse, uh, humor. It's a multisensory program. There's audio learning, there's engaging digestible, uh, nuggets throughout and, and, uh, yeah, and it's a, it's a beautiful, uh, fresh clean platform.Yeah. And you got a lot of us on there. We, uh, Vero mentioned the audio. We had a great time bringing a different type of learning to the app. So you'll hear our voices. We, we recorded these little snippets called pod drops, and we'll introduce each of the steps of the program with, uh, a little warm invite from the two of us. And then you'll hear us throughout the program, uh, either with a bit of information or a quote or, um, some personal experience because like, who wouldn't wanna hear us, Jim? Right.Everybody wants to hear you cause why you're here. It's why I have everyone on the, the show. My goodness,Hear this. They're gonna be like, let me at the app. and you've, you'll be in that too. You're everywhere. Um, so forgiveness and science would never have paired the two together. Mm-hmm um, you hear that you're supposed to forgive people. It's very much, um, you know, when we teach people how to forgive, uh, how does that even work? Right. When I think of forgiveness, I think of it externally, right? You had some wrong come to you and how do you let them, that person know that it's okay. And, and talking to you, it's not necessarily letting them know that what they did was okay. It's about letting them know that you won't let it bother you. Is that how do you define forgiveness and, and how do we really start that?So we, uh, um, we were a lot, all of us were taught the importance of forgiveness and, um, and it was either through culture, through our family, through our religious practice that we were born into. And so, uh, we are actually empowering the user to have forgiveness come from within them. Um, people can still use the ways that they learned, uh, how to forgive, but we F that a lot of, a lot of times we say we forgive, and then yet a little time further down the road, we think of the person that has quote, wronged us. Um, and we still have a physical reaction to it. So when you say the science, there's, there's a deep biological, chemical reaction that is happening when we live in this kind of quote unforgiveness. And so, uh, our heart rate can increase. We, um, uh, lose sleep. Uh, there's a lot of different ways that it is affecting us. And so when we teach forgiveness, it's really about how do we get to that fully, that full process of letting go and releasing it and knowing that it is that have the power within us to do that.So it's, it's not just, when you think about forgiveness, it's not just a mental health thing, there's physical attributes to it as well. And, and we talk about how the physical and the mental always, they go hand in hand, right? You know, what you eat can affect the way you think in all of those types of things, forgiveness is actually has a, a physical response. Is that what you're saying?A hundred percent? What if, what if we broke it down to, um, what if we took the word forgiveness out and spoke about stress, everybody's familiar with the effects that stress has on the body? Right. Well, the link between forgiveness and stress is unforgiveness and resentment and anger and irritation and grudge holding. So all of those things, right, that all of us do, um, contribute to the increased stress in our bodies. So does that feel like more of a linear type of, of thing to understand? Sure.And, and the resentment of, as we sit there, you know, we, when you think about coaching and what, and what everybody teaches people to do is focus on what you can't control, right? You can't control when somebody treats you like garbage, you can't control when something wrong happens to you, you can't, but you can't control how you react much easier said than done. Mm-hmm . So when we think about, it's almost meditative, the way you're doing it, it's, it's a stress relief of, you know, parasympathetic, nervous system, all of those types of things. And how do you turn off? But this is something that's got to become habitual, I would imagine, right? Because this will constantly come back. Resentment will constantly come back. When other stressors come in, you can always fall back on the resentment that you had and, and you're ultimately blaming other people. How does, you know, how do habits cut into this? How does accountability, uh, set into this? Because ultimately this is your responsibility for forgiveness, not necessarily, regardless of what somebody else does to you. Talk to me a little bit about that,Jim. I mean, um, you're hired, do you want a board position? I mean, you nailed, let's do it. Yes. Seriously.You, I mean, you're good. It's Jim's sandwich.It's it's um, that's exactly right. When we see it's a neuroscience program, we're talking about, uh, the neuroplasticity, uh, we re we talk about retraining brain. So that's how we start to create habitual, uh, patterns. So that behaviors start to, um, uh, express themselves in sustainable ways. Right. So, um, we've used the analogy, right? It can't like, uh, wake up one day and just run the marathon. Right? So we, it takes, it takes practice. It takes muscle memory. And so as we start to educate ourselves, I mean, these are things that we also needed to learn too. We've gone through 50 years of research. I mean, there has been so much in terms of cultural, culturally, how we forgive changes, um, our religious organizations. Uh, so it's all there, but it's so interesting. There's all these little or caveats that like, you can forgive if it's this, or you forgive on this day, or you forgive if you go to this person.And so, um, we respect and honor all of that. Uh, but there, but there's still that kind of like, like you said, every day we can wake up and there's new resentments. If any of us are in, um, partnership, we know that mm-hmm . And so every day a were given ample opportunity to be able to use this. And so we really believe that it's just, as we just don't know, we don't know how damaging living in unforgiveness is. We don't know the magic and miracles of forgiveness can bring in our lives. Once we excavate, uh, that resentment from us and, uh, start to really cut those chains that bind us what the possibilities are. And once we start to learn that through the program, because it is gently and lovingly reminding throughout, um, we start to lay down those new neural tracks so that when something happens, instead of safety of resentment, we have the confidence and the faith to now turn and go into a different direction of forgiveness.And if, if I could, um, piggyback on that, Jim, you mentioned coaching and, um, we can't control the outside forces. We can only control how we react, right. Um, it's the other person. We, if this, we teach forgiveness is innate. It's the power we have within ourselves. The minute we start putting condition on what forgiveness looks like, we give the power away. We wanna keep that here. So no matter what happens from the smallest transgression to something horribly traumatic, that we know that, that we have a choice and it's only about us. Otherwise we keep ourselves tied energetically to the very thing that's causing the resentment, the pain, the trauma, who would wanna do that. If you, if you break it down into a real simplistic terms, it's like, do you choose to be hurt? Or do you choose to be empoweredNow? Well, so some people are gluts for punishment.Yep.So let's talk about those people who are looking to be wrong, right. Who are looking for those types of things who are looking for, you know, uh, is that just some kind of mental health issue? Is that something where, you know, they have to, when we think about forgiveness, how does it, because I'm, I'm eventually gonna tie this back to corporate, right. And that's where I really wanna go with this because yes. You've said three things between the two of you. One is it's never about the other person. So it's individual accountability. What's personal capability in bringing that in mm-hmm . And where does that tie into things? Like you said, Vero, you said the word safety, so psychological safety and the lack of forgiveness. I think a lot of what you're talking about is not just forgiveness, but it's more important is the lack of forgiveness that exists in the workplace. How do you, how do you measure other people on that? How do you teach that in a corporate environment? Talk to me a little bit about, you know, individual personal capability, teaching that within the context of psychological safety and, and the corporate environment.So, um, so in terms of, in terms of the individual, um, I'm, I'm sorry, I'm just trying, I'm trying, cuz I'm I'm on the, it wasA loaded question with like 17 built into it.IOgrapher can I, can you read that back to me please? CanWe get a read back? yeah, let me break, let me ask it this way. Cuz I, I did ask seven questions in one we'll start with psychological safety.Okay. Yeah. So psychological,How do you create an environment where forgiveness is accepted or that, that doesn't reward? Lack of forgiveness.Okay. There was a, there was something about victim that was coming up when you were speaking in the, in the first time. Um, so how do we create a safe environment? And um, but I, I also want to, uh, validate and affirm that, uh, there's some really heavy things that need to be forgiven. And uh, and so when we're talking about forgiveness, it's not like we're putting ourselves up on a hierarchy. Oh, I have the power to forgive I'm bestowing forgiveness onto this. It's not about that. Um, and we want to, and along the way, we really, when we wrote the program, kept in mind the people that, uh, really have some big trauma that need to be forgiven. So, um, holding onto a resentment feels like a boundary, a safe boundary that I'm, I'm keeping up between me and my transgressor and that, um, that feels very real.Um, and so what we're, what we're saying is by forgiving them, we're not, um, putting our selves in harm's way. We're not putting ourselves in, in an, in an unsafe environment. It's just that we're releasing these binds that they have to us. Right. So we can forgive and never be in relationship with the other person. Again, we can forgive and never have to, um, let them into our lives. And so that's a really important distinction to make because we, a lot of us have been taught, forgive and forget. Yeah. Or, um, forgiveness doesn't mean that I condone what you did to me or that, um, you and I are ever gonna be friends again. Right. So that's really important in terms of safety. Um, so I wanted to just, uh, put that in there. And then in terms of, uh, co company and culture, we Denise and I talk a lot about this because we offer forg, um, to, uh, businesses now for bulk subscription because, uh, there is, um, widespread, toxic company culture going on.And so how can we start to again, create that, um, retraining the brain to under standing that like one, something people are gonna fail us every single day that is we're human, right. So, I mean, it's just gonna happen. Um, I'm gonna fail my husband. He's gonna fail me. Even those that we love our children, our children are gonna fail us. So in inside the, um, work environment, um, when that happens already having those tools and be being able to look at the person who has done something as an entire human being, right. Humanizing that person so that we're not just, um, hyper focusing on what they did. Um, but we're able to see, yes, they did that. And there are all these other things, right. They're a good parent, they're they have goodness in them. So it's, it's allowing, it's allowing ourselves to, um, have the capacity to be able to, uh, not be, um, not see, uh, not see someone as their act alone. So that already starts to invite in, um, a more way of how we, uh, are in our, in our careers.Um, Denise,Do you wanna add to that?I, I would love to. Yeah. Um, we are working with a lot of corporations at the moment. And so this pitch is right on the tip of our tongues and I want to, um, bring it back to the safety of the corporate environment. Boundaries are hugely important. We teach, um, having good boundaries in the app because otherwise you leave the door open for, uh, transgressions to just keep coming in. Right. Um, and when we forgiveness fluency and we, and we get that muscle, that forgiveness muscle tight leadership is more effect teams work more coherently employees have better time management skills because they're not sitting at their desk ruminating about the guy that stole their idea or, you know, screwed them out of a deal or whatever. Um, attendance is better. Productivity is better all because of forgiveness, because if I am a able to be, um, an empowered person with great boundaries and the ability to not let resentment live inside of me, I have all of this bandwidth for so many other things, creativity, um, you know, productivity, uh, just the things that a leader or a corporation will on an employee. They don't,It's amazing how much resentment just takes away from productivity and how much timeEvery, I mean, well, it starts with, you're laying in bed at night. And you're thinking about Joe Schmo, who, who got, who got your deal, who got your client or who, whatever who's, you know, and then, so it starts with lack of sleep, everybody, what lack of sleep does right then it's inflammation then it's you, can't, you're tired. So you can't concentrate. So now your time management's screwed up and your resiliency layer is thin. So you're irritable, you're nasty. You're not a good team player. You suck as a leader. If we could just draw the lines from, from all those things, it seems very like simple right now.And that be,Go ahead, Viro.I was gonna say, and that behavior's contagious, right? Yes. So then all of a sudden now, um, now my, uh, colleague and my team members are gonna pick up on this anger bug that I have. And then now it's just like, you know, and then that's starts to have that you, um, effect. And so now if we came in to work in from the forgiving lens, from the compassionate lens, um, from having a tremendous amount of self-awareness and presence, let's let that be the contagion contagious effect. Right?So in terms of that, and I, I have to ask this question because when I talk about psychological safety and I pitch it to clients, mm-hmm , they roll their eyes. Cause they don't know what it is. And they think it sounds like a very weak word mm-hmm . And when I think back to becoming a coach and leaving corporate, also wall street words, like love never came out, right. It just don't do it. Psychological safety sounds like something, you know, soft for millennials, forgiveness, compassion. This is a place of work. We don't all need to be friends depending on which generation you're from and everything else. We know that the science is there, that there's validity to it. And once I explain to people what psychological safety is, they say, oh yeah, of course. It's just, you know, that's just a weak title. Um, of course we want that. We want everybody to talk and, and feel comfortable and everything. That's what we want. How do we get people past the fact that it's a weak word? When in actuality, we know that the bravest leaders are the ones who are able to do it. And, and it's a very strong word. How do we convince people to sign on at the beginning to at least first filter is there's validity to this and it's not just kind of weakness. How would you answer that?Um, well I would say just asking the people, do you wanna live be life or do you wanna be angry all the time? Do you wanna feel sick and have lack of connection and control or do you want to have power and freedom? Um, because forgiveness may sound like a weak word, but it's actually the bravest step we can take in our own freedom, our own power, um, independence. Right. Um, I hear what you're saying, but 10 years ago people thought meditation was weak.Exactly. Right, right. And now you've got like whim off the Iceman breathing for, you know, whatever. Yeah. So,You know what you wanna be brave. You wanna be cutting edge, jump on the forgiveness wagon because that's the brave way to go. Not sitting in the old story, in the feeling of, of unhealth and unforgiveness. That's actually not brave. That's the weak. That is the weaker choice.And I'm sure we could tie it down like psychological, safety's tied to bottom line revenue forgiveness. I imagine very similarly. How much of this going back to what you said before, not leaving the door open for other additional transgressions. Right. And I think to Adam grants, uh, hello, kittycat Adam grants give her taker, um, you know, there are givers at work and there are takers at work and you'll burn out. Yeah. How can you head it off at the pass? Can you stop transgressions before they come? And how much of forgiveness is done in advance where you're communicating expectations of what's acceptable and not?Um, I don't know if, I don't know if you can, you can stop transgressions at the door cause people are gonna be people, right. It's almost like saying like I wanna lift li life without being triggered. Triggers are gonna happen. Right. Um, these, these, um, so I see a transgression, almost like a trigger. It's an, it's almost an opportunity for us to kind of, um, to go ahead and, uh, transcend what's happening. And so, um, but, uh, when we have really clean and clear boundaries, that definitely makes it more difficult for other, other people. Like we're already setting a precedence, this is my space. This is how I communicate. Um, and, uh, I'm loving with boundaries. Mm-hmm . And so, uh, boundaries don't mean that I, I have to be a jerk to anybody. Um, but it just means that I'm clean and clear. And so, uh, that start, that sends, definitely sends out a clear signal. And if we look at, from a place of energetics, um, you know, there's that saying, like, if you choose the right environment, it'll do the rest of the work for you. And so, um, so it's really, really important. Um, the energy that, that we have within us, that we're exuding out. That doesn't mean that bad things aren't still gonna happen. You know, mean bad things happen to good people all the time.And, and I think it goes back to building the muscle too. Like, um, the, if, if we are in a practice of something, it becomes intuitive. Um, and so with the, with forg, that's actually what we're teaching people. We're, we're reinforcing the practice. We're retraining rain, we're creating new neuro pathways. It then becomes an intuitive reflex so that the transgresion as zero said is always going to happen. But our response and our response time will change with time as that muscle gets really strong.Now, one of the words that keeps popping into my head is we talk is cons sequence, right? I know people who are not getting crossed at the workplace because people fear consequence. Right. I would never cross this individual because you know, it's gonna burn me in the end. And there are other people where you feel like fine. You can forgive me all you want, I'm still gonna, you know, do that transgression and you have that power and whatever. Where does concert sequence fit in or is that too externally focused? You know, what, where does consequence fall into boundaries and, and what does that look like?Well, there, there, there should always still be, uh, justice, right? We're not saying forgiveness doesn't mean like, you know, you have car blanche to do here's the other cheek. Okay. Here's the, you know, okay, let me do it myself. I mean, it is, it's about, um, yeah, I mean, if, if someone, if someone wrongs us, we should speak up, we should, uh, defend ourselves. Uh, that has, that is completely separate from forgiveness. And, and again, that's, that's so interesting. And I'm so happy you brought up this point, Jim, because that's what people think mm-hmm, , I've, I, that's what I thought. That's why it's seen as such a soft, uh, topic when it's like, when, because it's like, yeah, no, I'm not gonna leave myself open to, um, to people wronging me no way. And, um, and so that, that's why having the resentment gives that illusion sense of safety. Um, but no, stand your ground, speak your voice. Um, we're just saying don't hold onto it.Right? Let itGo internally. Let it go. That'sThere's something too. That's coming up for me. And like I say, this, uh, a lot, this ain't your mom's forgiveness, Jim, this is the modern approach to what forgiveness means. This is non dogmatic. This is, um, nontraditional. This is, I choose to recognize that X, Y, and Z happened. This is how I feel about it. This is what I lost. This is what I learned. This is how a human, the other person. And then this is how I move on from the event. And that's where all the power happens.So we're separating it and it is a unique, right. We're separating it from standing up for yourself. We're self-respect and all of those types of things. And this is really, you know, a mental exercise are there. I I've been thinking about this since we first talked and I don't know how to frame it. So gonna ask it who's better at forgiving men or women.Right. That's a great question. So we, um, there, there's been a lot of studies on this and, um, and they've even split up cultures to which cultures have more masculine traits and which cultures have more feminine traits. So women are better at forgiving. Men are better at forgetting. And so when we say, um, so when we say in terms of forgiveness, women are better at forgiving because we, uh, tend to, or, um, forgive more from the heart. It's, it's more of an emotional decision. Um, and when we do it, we're doing it because it it's for kind of, for the betterment of the tribe. So there's a collective that's part, that's called a collectivistic culture. And so that tends to have more feminine traits. Um, I'm doing it for us and men will forgive, um, um, and forget more easily, which is, again, we don't teach forgive and forget.Right. But, um, but is good, right? I mean, it's like the definition of hap yeah. The Def definition of happiness is good health and a bad memory. Right. So we're all about that too. Um, we're not negating that. Um, but men will forgive more decisionally from their head, which is, um, more for self, which is, uh, part of what's called the indivi individualistic it culture. So the United States is an individualistic culture. Um, and then we look at, you know, some, uh, uh, like, uh, some countries in south America are more, um, are more collectivistic. So it's, it's not so much in terms of like, who's better at it. It's just different ways of going at it. And, um, yeah, I mean, I, I, I bet women wish that they could forget more easily too. Um, but they, they, they seem to have they process it differently. That's all.Um, if I might drop in a personal little story, um, Vero and I were talking about this and I, I was saying, how 20 years on a trading floor, I witnessed some really gross behavior, not just, you know, the, the stuff that you read about, you know, in, uh, the articles, but physical anger come out on the floor. I mean, pun hitting with a hard, you know, those big, old, black hard phones. I saw people beating each other and it's primarily men. So I could say like, you know, everybody around me was, was basically male except for a few. And then they were just stop. And then it would be over because they needed the next deal. They were like, I'm beating somebody one minute and shaking hands the next minute, or having a, or having a beer after work because they need that guy for, for money in their pocket. So that was like a real, that, that was so obvious to me about how, I don't know if it's forgiveness, but it, it was definitely moving on from the, from the, from the event.Right. I, I feel like, you know, boys, growing up, you get into a fist fight and then it's over. Mm. Whereas I think of, you know, the story of just girls growing up, never speak to each other again, because they wore the same outfit or something ridiculous. Um, but, but you're right. You know, when I think of me, there are people wrong, me and they're effectively dead to of me. Like, I just don't think about them anymore and they're not, you know, I would never, but I'm sure if I saw them, it would bring everything back where I'm like, I don't like you. Um, but my wife on the other hand is fantastic about just addressing something and just clearing, clearing the air and, and getting rid of it. Um, is there a place for the forgive and forget, or is that just kind of irrelevant for this part of the, you know, do we need to teach more people how to address the, you know, yes. Logically I know I'm never gonna do anything with these people, and that's how I forget, like logically you're dead to me and that's fine. Emotionally. I haven't, is there a logic versus emotion component to this that that needs to be talked about?Yeah, well, we have to really be careful because I think that, uh, so there's something called bypassing, right. So if I just is like, okay, you're dead to me. I haven't processed what's happened. I haven't really like honored. There was, there was something that was done and it hurt that I felt. And, um, I need to honor that. And what, and what is my lesson in that? Right. So, um, so we can just forget through a, by just bypassing, I'm just gonna skip over that part. And so, um, so there's that, um, and, um, yeah, I mean, I just, so I, I just wanted to drop that in there because it's really important. I don't know if either is like more healthy than the other, the way the women do it, or the way that men are do it. Um, forgive and forget is amazing. If we can truly do it, mm-hmm right. That's really like, I'm gonna forgive really forgive because I went through the entire process. I did digested everything. I alchemized it. And I transmuted it out into space. It's done. And I'm able to forget every time I see you, my heart's not gonna start racing. Right. That kind of having that kind of charge, um, really shows us that we haven't really, we haven't completed the process yet.Right. We haven't addressedThat. You, you mentioned that with your own experience, Jim, right? Like if you see the person, all of a sudden you get jacked up again, it's because you parked all that somewhere down deep so that you could be a productive member of society, but the truth is it's still there. It's like, you know, hanging out, down there, taking up space festering. I like to use the example. I may have said this to you in the past of, you know, when you're, um, RS probably says like hearing this, but when you're recycling the peanut butter jar, it's the most annoying, difficult thing to get into the recycle bin because there's that stuff at the bottom of the peanut butter jar that you gotta clean out somehow, that's what real forgiveness is. It's getting to the bottom of the thing. That's bugging the crap out of you and, and real leasing it. And like Vero said, alchemizing it. And transmuting it. And then you're, then you're good. Then you can toss that thing in the, in the thing, in the,I mean, you could just throw it away anyway. But it's not the right thing. I hear what you're saying.You're right. But you're firedFinal question off the board very quickly. That was a very quick, is there a limit, is there a limit to forgiveness? Is it possible to, to do things or, or, or, you know, where does, where does forgiveness actually end or the, the ability to forgive end?We, we really believe that everything is forgivable. And again, we wanna honor that there are huge things that people, uh, will feel called to forgive huge traumas that have happened, but we've got endless stories of, um, people who've ordinary people who are forgiven extraordinary things and the magic that has come into their lives, uh, the miracles that have come into their lives, the, the places they've gone to that they've elevated to, uh, is, is, I mean, it's remarkable. Mm-hmm . And so, yeah, everything, everything is forgivable. And I, and, you know, we, we ask that question in our podcast, like, what's that thing that's unforgivable, mm-hmm, , you know, everyone, and everyone's got an answer and it's, it's usually similar and of course has to do around children. And, and so, um, so, you know, again, honoring, honoring how painful and devastating that is, um, and just knowing that there are people out there that are able to forgive that. And, um, and, and yeah, I mean, that's, that is, uh, and it's just anyway, so I, yeah, so that, that's our belief, but I'll let Denise drop in on that too.Yeah. I would say that, um, prior to doing this deep, deep work unforgiveness, I would've said that certain things were unforgivable. Um, what I've learned in these beautiful that we are going to include, um, in forgi 2.0, they're called, uh, catching miracles. Um, there are so many stories of people that went through horrific trauma and they made a choice to work through it. Of course, a lot of work through it. We're huge proponents in therapy. And we understand mental health is, uh, it has to be addressed tremendous traumatic situations. Um, they did the work and they decided to do other things. Um, they have, that's why I say, it's not your mom's for forgiveness. They forgave, they forgave even a way that, um, honored their loss and allowed them to move forward in a different capacity without being tied to that awful, awful thing that happened. And I, we look at them and say, if they can do it, anybody can do it. The human, the human heart and mind has the CAPA, this type of healing. And if one of us can do it, all of us can do it.Excellent. That's a perfect way to, to wrap it. I love the idea. I love the topic of forgiveness. Um, the final things we always end on the book recommendation and how people can find you. So why don't you tell me about how people can find you first, uh, more information be on bellweather hub.com, but how can people find you help support you? What's next?I'm just gonna give VES, uh, cell phone number out so they can just start calling her.Um, no, it's, we're really easy to find. So, um, if you wanna email us, um, I'm Denise D N is egi.com and VES at the same handle, Vero forgi com. You could also hop on our website, which, um, I will just drop in a little note. We are a little bit under construction, but live, so get your info on there. Um, we'd also, we're also on IG, um, forgi we're on Facebook for all you Facebook fans. Um, we're on TikTok, check on, check out our talks. You'reEverywhere. My goodness,My God. We're everywhere. And, uh, Vero you wanna share what our gift is?Uh, yeah, so our gift is, uh, anyone that is listening. Oh, we'd like to give the app away for free to them to download. So all they have to do is go on the website, um, put in their email address, uh, or actually, you know, they can just email us, right, Denise, and then we'll send a free link out. Yeah. Either wayYou'll quicker. If you email one of us, ifYou email us directly. Yeah. That's true. And, um, yeah, we'll send you the free link. Uh it's uh, O only for I iOS iPhone users. Now we're working on getting it available for Android. Um, yeah. And so favorite book recommendations. I love anything by David Seras, just because laughter is the best hum best medicine, and that's why we use it. Uh, we use humor in the program. Um, and, um, and from, from a more personal, uh, uh, I used to read the Alchemist, every new year's, uh, I reread that book and, um, I just, I just love the, uh, story of the journey and, um, really listening to how the universe is speaking to us and how we can really stay connected to flow. And so, um, yeah, that's one of my all time favorites.That's actually one of my all time favorites too. Um, I am, I brought a current read with me because I also thought this was tied into your audience gym. It's called emotional currency. Um, and the, uh, the tag is a woman's guide to building a ha a healthy relationship with money and it's, um, money as energy. And that the re better the relationship is with one type of energy. The better the relationship is with every type of energy. So I'm in the process of reading that I'll send my book review in to bellwether when I'm done.Yes. I want to know. Um,Also I just started re-reading untethered soul.Yep.Um, which, and I bought the journal to go along with it because though we're teaching forgiveness, there's always work to be done and there's always, you know, good stuff when you go deeper. So that'sMy all part of the journey. That's good.What's your favorite book? Jim?My favorite book is the Kani crystal, but I love your out chemist. Um, but I prefer sidhartha if you've read SidharthOh, I love Herman. He, yeah, amazing. SoThat's, that's myAmazing, that's a,Goodhart's my journey. Sidhartha Walden Kani, Christo. Probably my top three. SoThose are, oh, I love thatAlso.Yeah. Well, thank you. Well, thank you both for doing in this forgi forgi app. Look at them everywhere. I'll have their info contact info email address. You can get the app for free. If you have iOS better get on Android soon. Cause I'm an Android user. Um, but that's gonna be out soon. Use it. Come on, apple. My goodness. 20, 22, we need,We can open it up on an iPad. If you have an iPad appFor why would I have it had ?I mean,My wife has one, so we'll do it on that. Um, but forg is, is it, it is. I do honestly sincerely believe, you know, psychological safety is, is the buzzword of the day it's taking over organizations. Forgiveness is gonna be a significant part of that and right behind it. So this is, this is huge from personal accountability to changing a corporate culture. Forgiveness is a, a fundamental aspect to that. So Denise Vero, thank you so much for beingOn theShow. Thanks Jim.I appreciate it. And I look forward to seeing everybody out there soon.Thanks.Thank you so much for listening. Now, do something for yourself. Bellweather is much more than just a podcast. Join us@bellweatherhub.com, where you can read riveting articles, view upcoming events and connect with other interesting people. I look forward to seeing you out there soon.

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It’s been a year since we last spoke with our vaccine expert, Dr. Peter Khoury. We discuss the different types of vaccines available, if there is a best one to take, if there are side effects or dangers to be worried about, and whether or not Covid 19 will be here for the long run. Dr. Peter Khoury, is the President and CEO of Ology Bioservices Inc. He is an expert on vaccines and biologics and during his 30-year career, he has worked for the Bill & Melinda Gates Foundation, Merck, and Baxter International. Dr. Khoury has involved in international forums on vaccines, pandemic planning, and biodefense preparation, including working with the Olympic Committee. TRANSCRIPT: Intro: 0:01 Inventors and their inventions. Welcome to Radio Cade and podcast from the Cade Museum for Creativity and Invention in Gainesville, Florida, the museum is named after James Robert Cade, who invented Gatorade in 1965. My name is Richard Miles. We’ll introduce you to inventors and the things that motivate them, we’ll learn about their personal stories, how their inventions work and how their ideas get from the laboratory to the marketplace. James Di Virgilio: 0:39 Welcome to Radio Cade . I’m your host, James Di Virgilio. And today we are bringing you a special episode. It is part two of the, everything you need to know about vaccinations and COVID-19, it’s been almost a year since I last spoke with Dr. Peter Khoury, you can catch that episode anywhere you listen to this podcast. Dr. Peter Khoury is the president and CEO of Ology, Bioservices, he’s an expert on vaccines and biologics. And during his 30 year career, he’s worked for the Bill and Melinda Gates foundation, Merck and Baxter International. Dr. Khoury has been involved in international forums on vaccines, pandemic planning, biodefense prep, including working with the Olympic Committee. Dr. Khoury, welcome back to the show. Dr. Peter Khoury: 1:20 Thank you, James. And it’s unfortunate. We can’t do it in person. Certainly. I’m sure you, myself and others are so used to doing teleconferences and Zoom calls. So we’ll see how this goes. And hopefully you can hear me well. James Di Virgilio: 1:35 Yes, we can. We’ll make this work last time. In our first episode, of course we were together. We were in a large room sitting far apart, but it is always great to have, of course, the person you’re talking with in front of you, like all of the listeners know and understand as well. So since the last time we spoke, a lot of things have changed, but really a lot of things that you had talked about on the first episode have essentially come to pass. You mentioned there’d be a potential small wave of infections followed later on by a much larger wave of illness that certainly happened. And then we got into the discussion, which is really going to be the crux of our discussion today of essentially game theory and viruses, which again, viruses are smart. They react, they change, they have different strands. I think a lot of the public across the world has learned about these things. And how do you deal with them? How do you stay one step ahead. So let’s open up now with that in the background and ask you sort of this big question, looking back now, what happened that maybe you didn’t foresee the first time we spoke? Dr. Peter Khoury: 2:29 There’s a couple of things and they, I guess aren’t really biology related, but they really did make an impression on me and were something I did not foresee. The first really was the amount of compassion and caring that people show when they’re in uncertain circumstances. It did once again, show me that compassion is an inherent trait and caring helps ease the burden. A pandemic can cause think about the long hours and risks that healthcare workers put themselves in, especially at the beginning of COVID-19. And there was so much unknown in so many people being infected and to be an emergency room nurse or physician at that time, and having to put in those long hours and put yourself at risk and your family at risk and not really sure if one mask or two mask or a shield or what exactly was going to really protect you, but they came in for work day after day, policemen, firemen, emergency workers, all of them. It’s amazing for them to really take care of those who had severe cases of COVID-19. So I think that’s the first thing that I didn’t really foresee that there would be that kind of positive response. And so many people that really took up caring for others. The other thing that I didn’t foresee was the ability of people who may otherwise be intelligent to actively ignore the science and the data. And instead believe what I thought were ridiculous, conspiracy theories and false information generated by self-proclaimed experts whose credentials are measured by the number of people who follow them on social media. So I was surprised by that, that otherwise people that I thought were pretty intelligent would trust that for their information instead of the experts in the field. Actually, there is another thing, a third thing that I didn’t really foresee a year ago, and that’s really how different people’s tolerance for being inconvenienced and then their mental calculation of the risk and reward removing something that is inconvenient. So simply stated their reasoning for justifying doing something that increases their risk . I happen to live out towards one of the most populated Springs in the area. And it was amazing during the weekends of this past summer, the hundreds, if not thousands of people that would go to these Springs and no mask, no nothing, whole family. And they would put themselves at risk. And it’s hard for me because I wouldn’t do that to actually see that. And now here we have, I think at least two States, Texas, and Mississippi that are basically taking down everything, no mask, full restaurants, everything back to normal, and I’m afraid. We’re just going to see another huge wave from this. So people need to understand, yes, you’re going to be in convenience for awhile , but that’s the only way to stop spreading a virus like this. Or of course, get everyone vaccinated and protected at least to a number where you get protection of the movement of the virus amongst a population. James Di Virgilio: 6:05 Yeah you mentioned an interesting narrative there with listening to experts and in my own field of investing, I like to tell people all the time, if you ask me questions about investing, I can speak as an expert in the past. This is why this strategy worked here are the data sizes and samples. Here’s the research done here. So we know it’s worked in the past. Here’s, what’s likely to work in the future, but if someone asked me six months from now, what exactly is going to happen in this market or this investment? The only right answer is, I don’t know, and neither does anyone else. And there seems to be some confusion between experts that know how to speak on things that have occurred, that they’ve witnessed and people making prognostications, using whatever kind of modeling, either simple, or as you mentioned, an opinion that comes from your mind and gets put onto social media, prognostications are difficult, but the hard data, the data we’ve observed, the data we know to be true of course tells a different story. And that I think is what you’re looking for. Obviously in a free society for people to begin to clean to what is the truth are things that we’ve observed before. So let’s set the stage for vaccinations. In general, last time you had mentioned, there’s essentially five main ways that you can create a vaccine to overly simplify and with Corona virus with COVID, we have essentially not used all five of them. If you could kind of walk through the landscape right now for the vaccines, we have the ones that may be worked on, and then we’re going to walk through them because I know that’s a huge question area for most people. Should I get an mRNA vaccine? Should I wait? What’s the difference? Is it risky? So if you could set that landscape again, what these vaccines are, and then we’ll dive into each one and give everyone out there a good chance to grasp what the differences are. Dr. Peter Khoury: 7:41 Sure. And I have to admit, I didn’t listen before this, to what I had said a year ago, but there are tried and true methods for making a vaccine, whether it’s a live attenuated vaccine, where they take either a virus or bacteria and they make it. So you have, what’s called a subclinical infection where you don’t really get sick from it, but your body responds as if you did. So you produce antibodies and an immune response to this modified bacteria or virus that’s been attenuated, or sometimes you just kill it and put it in hall in the person. An example is at the early days of vaccines, the very first one was a smallpox vaccine made with Cowpox. And they realize that milkmaids were not getting serious cases of smallpox it’s because they were infected with cowpox, which was a milder version. And that’s sort of like an attenuation in a sense. And so then they were able to take that and literally just bake it or whatever you want to do to kill the bacteria and use that. Then as a virus itself, you can also put it in a mixer and slice it up and you have a bunch of small pieces of a virus or a bacteria. And I say a mixer. It’s nothing like that, but you get the idea of slicing it up and in your body sees that as foreign. And it can develop an immune response to that. But the vaccines that are now on the market actually use newer technology, which really is ingenious. And unfortunately people fear mRNA’s or DNA and they think, Oh, this is genetic engineering. And they’re putting something into me and it’s integrating into my chromosomes. And I don’t know, the government can track me because of that. And it’s nothing like that. Really. If you look at it in the science behind cell biology is just amazing what each of your cells can actually do. And it’s really using that mechanism as a small factory in itself. So I think most people realize there’s a third vaccine that was just approved by the FDA, by a company. You know, them as Johnson and Johnson, they have a subsidiary called the Anson, which is out of the Netherlands, their vaccine portion of the company. And so this new vaccine just came on the market. It’s given us a single dose and the other two, which had been around now for a few months, the Pfizer in Moderna vaccines, those are really two dose vaccines. And so the Pfizer Moderna vaccine utilizes this manufacturing platform that you mentioned, which is mRNA or messenger RNA. What they do is they have this piece of genetic material that in a sense codes, it’s the recipe, for what’s called the spike protein or part of the spike protein, which is part of the Corona virus. And they encapsulate it in like this fatty particle. So it’s called a VLP. And so inside this, let’s say glob of fat, little glob of fat is this little piece of genetic code. Well you’re cells need energy. And so when they see that they use that for energy, this gets injected in your arm and your cells in your arm , see that those fatty particles and they start sort of sucking them in for energy use. And as they suck them in. And the middle is this little piece of genetic material, which is the messenger RNA once inside the cell . Well , your body has all the mechanisms to take that recipe, which is in a sense listed on this piece of messenger RNA and start producing the protein it’s encoded in it, which is that spike protein. So that spike protein is then released from yourselves and other cells. See, it may say, Hmm , that’s not part of our body that’s foreign to us. And so it generates immune response by your other cells, by your immune cells. In those remember seeing that particle after it eats it up or whatever. So it sees this spike, protein decides it’s foreign to your body. The immune cell then ingests that, but it remembers seeing it. So if you’re ever infected with a virus, your body immediately elicits an immune response. You don’t even know you were infected because antibodies instantly take up the Corona virus that you’ve been infected with. And that’s how you’re protected by that type of vaccine. Johnson and Johnson vaccine actually uses a different type of technology. They use what’s called a viral vector in what that is. It’s a virus, the one they use is called adenovirus, 26. It’s basically a virus that’s similar to what the common cold viruses is. They genetically engineer that. So it can infect cells, but it won’t replicate inside the cells. So it can’t spread throughout your body and give you any kind of infection or whatever, but it does have inside of it , the genetic instructions like that recipe again, to make that spike protein that is used to elicit an immune response. So instead of being carried in these little fat or lipid balls, the genetic instructions are injected by that weakened virus into the arm cells. And then they make that particle, which is the spike protein of the Corona virus. And that again is identified by your other cells as being foreign in your body. And it elicits the immune response. So that’s sort of the mechanisms for the three different viruses. Again, hearing that people consider that genetic engineering, you know , I just want to set the record straight. There is no modification of your genetics or of the virus genetics. So what is happening is, as I said, it’s truly amazing. If you think about that, the cells in your body, which have all the machinery to make any kind of protein, it has the recipe for that’s what’s included on your chromosomes are all these recipes for proteins that make your eyes a certain color and your hair, a certain color, et cetera, all it’s doing is simply introducing a new recipe, which either is delivered by a harmless virus that won’t replicate or that’s provided in like this little energy bar, these little lipid fat balls, and that recipe delivered uses the cell machinery to make the part of the spike protein that causes the immune response. Sorry, that’s a long-winded answer, James. James Di Virgilio: 14:41 No, it’s a good start. So mRNA founded in 1990 or so essentially by a Hungarian scientist, she had this novel idea and then all the way up until COVID-19 was never used or approved. Should there be concern that it now for the first time is being used in a vaccination that is going to be used worldwide. If it’s never been used in the real world before. Dr. Peter Khoury: 15:04 Now, it really should not be in the reason as is it does not modify your genetics at all. It literally is just, as I said, use the mechanism of your cell to produce a protein. I’m trying to think if there’s any other comparable in either veterinary medicine and nothing’s coming right to mind. But as I said, it’s not genetic engineering by any means. It’s literally putting a small piece of messenger RNA, which is normally in your body. So your chromosomes, which are DNA are transcribed into messenger RNA, which is read to make the proteins, this just skips the DNA part and goes right to the messenger RNA. James Di Virgilio: 15:47 So we don’t have to worry as the public, as far as we can tell scientifically that this is going to turn into something that’s going to alter body chemistry cause sickness down the road have any longterm effects. As far as anyone can tell. There’s nothing about these MRNs current vaccines that we should be afraid of. Dr. Peter Khoury: 16:03 Right. And it’s new technology. You really can’t tell the future. All indications are that it’s very safe in very efficacious. The amount of clinical studies that go behind products like this before they’re released is truly tremendous. I think that there would have been clear indications as they were either studying this technology early on or as it gets further on and goes through the phase one phase two and finally phase three clinical studies that there would have been warning signs that there were problems, but certainly none have arisen yet with this technology. And if you think about it, theoretically, there really is very little, if anything that could rise from having this done, but you never know until time’s passed. James Di Virgilio: 16:55 Right? The famous French economist in the 1840s, Frederick [inaudible] would talk a lot about unintended consequences of whatever you put in place in society. There are always unintended consequences that you cannot foresee, but scientifically it is good to note like you’re mentioning as far as anyone can tell scientifically this is not injecting a large risk into your own body. It is not altering genetic code, as you mentioned. Um , and that that’s , that’s something to hang on. So now let’s talk about something more nuanced. So we have two mRNA vaccinations that are available. Obviously big advantages are it’s much faster to bring them to market logistically before we get into the other ones. Are there any hurdles with an mRNA vaccination logistically with regards to freezing or refrigeration or transport that maybe would give a more traditional vaccination at advantage and delivery and rollout ? Dr. Peter Khoury: 17:41 Yeah, actually there is. I know with the mRNA vaccines, as far as the fats surrounding it, the VLP structured itself needs to be kept at low temperatures. So would that Moderna and Pfizer vaccines, the storage in shipping was between minus 80 centigrade minus 60 centigrade. So that’s minus 112 degrees Fahrenheit to minus one 76 Fahrenheit. So that caused a lot of trouble at first for States or for injections sites and clinics because they didn’t have those special freezers. We have them because of the work we do here, but they’re just not readily available. People don’t keep these in physician offices , et cetera. But what they did do is immediately started looking at temperature changes and how long the vaccine in a sense could survive at regular refrigeration temperature or in a freezer, regular freezer. So the FDA did ease up on those requirements, but even now that vaccine still only can be held in a refrigerator for five days and then must be used within six hours of being thawed and diluted. So there is a small window, and it’s because of those VLP that ball of fatty acid , that carries, that, that makes it. So you have to have careful handling per both the Johnson and Johnson vaccine, which uses the adenovirus actually can be kept at refrigerator temperatures for up to three months. So it’s far easier to store and ship because of that. Another difference between these one, as I mentioned is a one dose vaccine and that’s the Johnson and Johnson vaccine in the Pfizer and Moderna, the vaccines are both given as a two dose series. Obviously giving one dose is much easier since there’s no follow-up visits, which involves making sure the person in the vaccine are there at the right time for dose number two. So coordinating all of that goes away, where if you do have to come back for a second dose with the Pfizer/Moderna vaccine, you obviously have to coordinate it. So the person and the doses they’re at the appropriate time to administer at , but there are clinical studies were done a little differently. So when you look at the efficacy of Pfizer and Moderna, those vaccines had a rate of effectiveness during the clinical trials of 94 to 95%. So that means that they vaccinated people and they looked for antibodies production. In those people. It makes sense . Every hundred people that we vaccinated basically 95% over, I think it was four weeks had developed immunity by , in contrast with the Johnson and Johnson or the Yansen vaccine, they said it was 85% effective against severe disease and a 100% effective at preventing death. So during their clinical trials, not one person who got the vaccine. And I think there were 44,000 died from COVID-19. And I think 100% didn’t even go to a hospital. There were some people that did have severe disease about 15%, and there were people that had what they call moderate to severe illness. So that would be in a sense they were home, not feeling well, et cetera. So it’s hard to compare apples to oranges. In this case, since one was a two dose vaccine looking purely at efficacy and production of antibodies in the other was a one dose looking at severity of illness. So getting either vaccine is a great thing to do. If you get the one dose vaccine, you don’t have to go back for a second dose, but there is some chance that if you’re exposed to COVID, you may get a mild illness from COVID. And in fact, there’s a lower chance of only 15% that you could have a severe illness from that. We don’t know if you’ll die from it, but for the 44,000 people they had in their clinical studies, I think it was 44,000. None of them died from illness. So I think those really are the main differences. There’s a little difference as far as how quickly you’re protected that Johnson and Johnson vaccine works about two weeks after people get vaccinated with Madonna and Pfizer people don’t get full protection until about two weeks after the second dose. And the second dose is usually three to four weeks after the first dose. So from the very first dose, you’re talking five to six weeks after the first dose and you’re fully protected. James Di Virgilio: 22:53 Let’s bring this down to the granular level now and get to a decision point. So let’s assume, and I’m going to throw a fourth one in here with Novavax, which may or may not come through, but it’s another different type vaccine just to give us the thought experiment of being, let’s say late August, you haven’t had a vaccination yet. And you have this choice in front of you. You essentially have the mRNA, which you’ve mentioned is Moderna and Pfizer. You have Johnson and Johnson, and then you have Novavax, which is going to be one of the most traditional and time-tested vaccinations. If it makes it again, we’re speculating here, just to give an idea of what this may look like, and you have a choice. Does it matter Dr. Khoury, which one you choose? Is it simply saying, you know, it doesn’t really matter. Take either one of these for convenience or one you can follow through on, or is there a more educated decision that needs to be made if you’re facing a choice between these let’s call them three different vaccine deployments, Dr. Peter Khoury: 23:44 Right? Of course, a choice like that is personal on whether people want it to be vaccinated or not. I would say that the first hurdle is get vaccinated. There is no doubt that vaccination protects you when it comes to the choice. And there are so many people in videos, out of people, literally on their death bed, dying of COVID by themselves, in a hospital saying, I wish I had not gone to that party. I wish I had done this or that. You may think you’re otherwise healthy, but you’re playing Russian roulette with something that impacts people in very different ways. Even though they think that I’ve never been sick in my life, this couldn’t impact me. You would be surprised at the number of younger people and other people that get this disease and either suffer long-term consequences from that, or truly die within a few weeks of contracting the virus. The question is if you had the choice of vaccines, which one based on the technology used would be better. I always tell everyone if it’s been reviewed by the FDA in the United States or the other one is the Korean FDA. Korea has an incredibly competent FDA based really off the US FDA and both are very, very good at looking at the risk and rewards of every vaccine, European union, also very particular and conscientious about looking at the impact of vaccines. So I would say that if it’s been approved by the FDA in the United States, it’s a safe and effective product . So if Novavax does get approval, I would not hold back at all on getting that vaccine versus either Moderna Pfizer or the J&J products. All of them are winners. If you get at , if you’re needle shy, obviously you may want the one dose versus the two dose. So there may be some advantages mentally for you there. If you want to make sure the odds of being protected the best look at efficacy after two doses, it’s much higher than it would be after one dose. But again, all of them are safe, effective vaccines, and the technology makes very little difference in this case. James Di Virgilio: 26:12 So the take home there is assuming that they all have FDA approval and you have that choice. The reality is you don’t need to spend a ton of time researching which one to get, because the odds are, all of them, of course are going to work for you. And there’s just different sort of personal mechanisms. Like you mentioned one dose or two things like that. But right now there’s not a significant difference that should have you necessarily favoring one over the other. If you’re looking to get a vaccine. Dr. Peter Khoury: 26:37 Right. Just based on the last sentence you mentioned, I’m not sure what the composition is of the vaccine that may come out later on this year, but I know the Moderna, the Pfizer, the J&J vaccines do not have adjutants in them. So in they’re not produced like an egg. So if you have an allergy to eggs or egg protein, it’s no issue with these vaccines. If you have been issue , there’s what are called adjuvants, they help boost the immune system with certain vaccines. None of these have this. So they’re pretty pure vaccines. Some of the older technology you’ve had to use either a chicken, eggs, or hens eggs to produce the product. I think the one you had mentioned is a Viro cell product . So it is not produced in, in hens eggs, but some of that older technology does use adjutants and other things, which is that chemical treatment. So some people have had reactions to that in the past. James Di Virgilio: 27:39 To look for individual things that maybe you yourself have an allergy to, or , or some reaction to, but all in all, if it gets FDA approval at this stage, it’s gone through the rigors. And if you want to get a vaccination again, no need to sparse out exactly which one to get. The differences are not going to be, as you mentioned significant, despite the fact that they are in fact different delivery mechanisms. Now let’s talk about different variants. This has obviously gotten a lot of news play here. When we first talked, we talked about how stable COVID-19 was. Uh , we also talked about, of course, the fact that virus has changed and that we could expect COVID-19 to change. We just didn’t know how yet, given what you’ve seen with the variants . And we know we’ve seen numbers, Johnson and Johnson is almost 70% effective against variants. Each one of these is a different number. What is this variant landscape look like to you? And I know you don’t see the future, but as of right now, if I get a vaccine tomorrow, do I have decent protection against the variants we’re aware of right now? Dr. Peter Khoury: 28:32 Yeah . It’s important that people get vaccinated as quickly as possible because the quicker we can shut down the circulation of this, the chances of it mutating in doing what I had talked about is drifting and shifting gets eliminated. So through replication, that genetics change is virus adapt to their surroundings, just like humans do. If you look back at Neanderthals and us you realize that certain people are born with traits that allow them to survive better. In certain circumstances, that’s true with virus and bacteria. It just happens thousands and thousands of times faster than we replicate. So literally in 24 hours, virus have gone through 10,000 fold replications where humans takes nine months to birth out a baby. And it literally happens so fast that these genetic changes in that adaptation to your surrounding can happen very quickly. And as long as those changes have little impact on the spike protein, that’s a protein has been utilized by all manufacturers that I can think of as the target for the immune response, then really vaccinating now should protect you against most of the variants. The variants, it wouldn’t protect against would be ones that have totally shifted away from that current spike protein configuration. So if there’s a little drifting away that protection will go down a little bit. Some people won’t be protected as well, but if there’s a major shift, it doesn’t provide any protection. Now you don’t know if that’s going to happen. I talked to other people that are experts in the field, and some believe what’ll happen is this’ll become like the yearly flu vaccine that will be able to see the shifting happening in other parts of the world. And people will just change the messenger RNA or whatever it is that’s coding for the latest variant that’s circulating around the world. And then a few years later, if it changes again, you need to get another dose of vaccine against that. I’m hoping we don’t have to do that. I’m hoping that we’re able to shut this down as quickly as possible and make it just a one-time pandemic event and basically eliminate it from the world soon. James Di Virgilio: 31:03 And that’s a great point. And that’s something again, that wisdom would say, no one knows the answer to that question, but certainly we hope that COVID is not here to stay like influenza or influenza has some mutation strains that become very famous, like the Hong Kong flu in the sixties, for example, right. That’s influenza just a different strand. It’s still here today. Obviously it’s just not that significant bumps. So that’s a , we’re all hoping for, as you mentioned, and of course, like you said, one of the best ways to make sure that happens is if everyone does get vaccinated faster than you’re going to give this virus less of a chance to make these game theory changes, to look at what humans are doing and respond and say, okay, well, I’ll do this to try to keep myself alive. Essentially you’re reducing its options. And if you’re doing this options further enough, it may just totally be gone. Of course, that is over simplification . So here’s a question for you. What happened to the flu in this flu season? The CDC records indicate that the flu is essentially non-existent despite about a million tests. You’ve had very few positive results at all. Hospital admissions are down to levels, never seen before. What does influenza and COVID have to do with each other? What does this mean for the future? Any thoughts on that? Dr. Peter Khoury: 32:10 What we may be seeing is just impacted by the distance. People keep from each other and making sure they’re washing their hands, wearing masks, all of that impact flu also the transmission of flu. So I think flu is still here. There are cases, but people have become very conscientious about spreading viral diseases during this time. I think once the unmasking happens and people are back to what we consider a normal life, I think you’ll see dlu come back to the levels that it was before. James Di Virgilio: 32:50 Yeah. It’s an interesting thing to follow, obviously, because one of the major fears was, you know, what if you had COVID and influenza stacked on top of each other, and we don’t know yet how much these things co-mingle. Do you get one and not the other, can you get both in States like Florida, which had been largely open, you still have extremely low or non-existent really statistically influenza cases. There’s just a lot that we will unpack obviously in the future. All right . Let’s ask you this big question before we talk about what you were working on to close up today’s episode. So let’s put you in hindsight mode a year ago. If you knowing what you know now had the power to implement one change to impact the outcome of what we’ve gone through in the past year or so, what would that change have been? Dr. Peter Khoury: 33:30 Hmm , I think if truly there was a chance of getting all governments in the world together. I mean, that would potentially never happen. But I think in hindsight, if they were able to take a year and take a look at where we are now and the impact that it’s had on people’s lives. So the morbidity, the mortality, the impact on economics, all of that. And you could take all the decision-makers to this time and look back. I think all of them would agree that if we literally shut the world down for a week, made everyone stay home, put in very, very serious measures, whether it was a week or even two weeks that we could have stopped this right at the beginning, it literally wouldn’t have been able to become what it did. And if you look back at countries going to use Korea as an example where they did exactly that, or China or India, here’s a country with over a billion people and boy did an impact the number of cases they had much less than we have, but it’s an inconvenience obviously to do it. And if we had done something like that worldwide for a week or two, of course, people would have been inconvenience without knowing in the future of the impact or what that could prevent from happening. So looking back and having that hindsight now it’s nothing I could have done alone or whatever, but that would have been my advice to get as many people to stay home and watch Netflix or whatever you want to do for two weeks. Just get ready, implemented day that it starts in the day and the day it ends and enforce it . James Di Virgilio: 35:10 Yeah. It’s so interesting that the topic for a whole different podcast, like you mentioned, the hindsight hindsight analysis is always undefeated because you have information you don’t have. And as you mentioned, the question then becomes, how many days is it? How long is it? What if it doesn’t work the way we think it works? So then what happens is there’s a lot of decision points, but that’s why it’s a hindsight question is knowing what we now know that it did spread, it was highly contagious. It was going to go all over the world. Of course, as with any virus, if you can isolate you reduce the spread, right? It’s like playing tag as a kid. If you’re too fast and they can’t touch you and tag you, then you’re not going to be it. And so , uh , that’s an oversimplification, but that’s a good point about potentially the future. What do you do the next time this happens and what happens if it does fade away and its own. Okay. Will you said we lost 14 days, 14 days, certainly a lot better than a year. So lots of interesting thoughts there, let’s bring this right back down to what you and your company are working on. Tell us a little bit about an update. Last time we spoke, you are working on something COVID related. Tell us what’s going on with that. Dr. Peter Khoury: 36:07 Yeah, so we work with the US government on a couple projects, specifically with the department of defense to help protect military personnel and war fighters. And so we manufacture a vaccine for COVID-19 and we manufacture what are called monoclonal antibodies, which are also utilized to protect and treat, actually treat COVID infections. Both of these are in clinical studies. Currently we are expanding here in the Gainesville area. We’re in Alachua, we’re doubling our capacity . So the construction is underway for this. And I think it’s a great opportunity for this region because of University of Florida, some of the great research that goes on at that university in gene therapy and cell therapy, and in vaccines, it makes a lot of sense for us to make an investment, expand our workforce. So we’ve almost doubled our workforce. Since I last spoke to you, we’re over 300 employees during 2021, we expect to expand by over a hundred more employees. So there’s a lot happening here. All of that, very cutting edge science and all use to provide protection against infectious diseases. James Di Virgilio: 37:34 And let me bridge a gap here, because this could be maybe the best way to end this podcast. You obviously are an established expert in this field. You’re an expert on viruses on vaccinations, on deliveries. You’ve done it for your whole career. If you saw something that you thought was risky or reckless or not good for society or the population I’m imagining you would be standing on the rooftop, shouting this out, don’t take this vaccination, don’t do this. This is not safe. That would be correct. Dr. Peter Khoury: 38:01 It’s funny, James, because those that know me well, including our employees here, know that I speak the truth, I have great courage of conviction about what I say. My father was a United Methodist minister. My mom was a nurse that took care of some of the riskiest patients and both were just devoted people to what they did. And I think one of the most important things for any human being is their own dignity and not being able to stand up for what you think is right. And when you see something that, especially if you’re a professional and you know, information, not raising your hand saying that there’s an issue in something’s wrong is not good at all. So it’s not part of my being to ever cover anything up or whatever. And that’s a philosophy actually of our business here. I attend every one of our new employee orientations. And I tell them that everyone has the right to stop the process. If you see something being wrong done, or you’ve done something wrong immediately, we will stop. We’ll look at it, figure a fix and find a way of putting a parameter around it. So it never happens again. That’s all I care about. No one’s getting fired. You’re not going to be yelled at. We’re going to find a way. So it doesn’t happen again and fix what happened. That’s all there is to it. James Di Virgilio: 39:27 Yeah. That’s such a great commitment. And I think that perhaps is something that’s really gotten lost during this pandemic, is that not everyone is on two sides of offense fighting with each other and not every expert one way or the other is out there just trying to run a political agenda. It’s safe to say that many people are doing exactly what you said. Hey, if I think this science looks good or this looks good, I’m going to say this is safe. And if it’s not, I would say the opposite. And perhaps that bridge, as we mentioned, is something to move forward as a free society in the future. We’re looking for truth via evidence and data. And recognizing, as you mentioned, there’s a lot of people with that, very commitment. You’re simply trying to follow the evidence and say, Hey, look, I think this is what’s best for you and your family. You’re my neighbor. I love you. I care for you. And this is why I’m saying that. So a wonderful stuff as always, thank you for being with us. He is Dr. Peter Khoury, the president and CEO of Ology, Bioservices. You can find them on the web with a quick Google search. And of course, as we mentioned before, your illustrious bio, an expert on vaccines and biologics, and certainly one of our favorite guests here on the Radio Cade podcast. Thank you for spending a considerable amount of time with us today, Dr. Khoury. Dr. Peter Khoury: 40:29 Always my pleasure, James, thank you. James Di Virgilio: 40:31 And for Radio Cade I’m James Di Virgilio. Outro: 40:35 Radio Cade is produced by the Cade Museum for Creativity and Invention located in Gainesville FL. This podcast episodes host was James Di Virgilio and Ellie Thom coordinates, inventor interviews, podcasts are recorded at Heardwood Soundstage, and edited and mixed by Bob McPeak. The Radio Cade theme song was produced and performed by Tracy Collins and features violinists , Jacob Lawson.

Red Wings Rant Podcast brings the brotherly love and war to the Detroit Red Wings conversation. They may sound the same, but their opinions couldn't be more different. Born and raised in South (east) Detrooooit! This wild ride could go AAAANNNNNYWHERE!Website: bodpodcast.com & brothersofdiscussion.comTwitter: @bodhockey IG: @brothers_of_discussion@hockeypodnet

Red Wings Rant Podcast brings the brotherly love and war to the Detroit Red Wings conversation. They may sound the same, but their opinions couldn't be more different. Born and raised in South (east) Detrooooit! This wild ride could go AAAANNNNNYWHERE! Website: bodpodcast.com & brothersofdiscussion.com Twitter: @bodhockey IG: @brothers_of_discussion@hockeypodnet Learn more about your ad choices. Visit megaphone.fm/adchoices