Podcasts about Ending Aging

In this episode of the Longevity Optimization Podcast, Dr. DeGray discusses groundbreaking research in aging and longevity, focusing on combination therapies, the hallmarks of aging, and the potential of stem cell and gene therapies. He emphasizes the importance of rejuvenation over merely slowing aging and explores the role of the immune system in health. The conversation also touches on biological age testing, lifestyle factors, and the future of gene therapy in enhancing longevity. Aubrey de Grey is a British biomedical gerontologist and the founder of the SENS Research Foundation. He is a leading advocate for regenerative medicine, focusing on reversing the effects of aging by repairing cellular damage. Known for his bold vision of life extension, de Grey believes that with advanced therapies, humans could significantly extend their lifespan. He is the co-author of Ending Aging, and his work continues to shape the future of longevity science. Takeaways Combination therapies are crucial for understanding aging. Rejuvenation may be easier than slowing down aging. Stem cell therapies hold great promise for the future. The immune system plays a significant role in aging. Biological age testing can provide insights into health. Gene therapy is a promising avenue for longevity research. Lifestyle factors have limited impact on lifespan extension. Understanding the hallmarks of aging is essential for interventions. Preventative maintenance is key to longevity. The future of aging research is bright with new technologies. Chapters 00:00 Introduction to Longevity and Aging Research 02:50 Combination Therapies in Aging Research 05:57 The Hallmarks of Aging 09:12 Interventions for Rejuvenation 11:57 Stem Cell Therapies and Their Future 15:03 The Role of the Immune System in Aging 17:56 Insights on Aging and Rejuvenation 20:47 Biological Age Testing and Its Implications 24:01 The Future of Gene Therapy in Aging 26:49 Lifestyle Factors and Aging 30:04 Conclusion and Final Thoughts Learn more about Aubrey's work: https://www.levf.org Visit Kayla's website: KaylaBarnes.com

Our topic in this episode is progress with ending aging. Our guest is the person who literally wrote the book on that subject, namely the book, “Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime”. He is Aubrey de Grey, who describes himself in his Twitter biography as “spearheading the global crusade to defeat aging”.In pursuit of that objective, Aubrey co-founded the Methuselah Foundation in 2003, the SENS Research Foundation in 2009, and the LEV Foundation, that is the Longevity Escape Velocity Foundation, in 2022, where he serves as President and Chief Science Officer.Full disclosure: David also has a role on the executive management team of LEV Foundation, but for this recording he was wearing his hat as co-host of the London Futurists Podcast.The conversation opens with this question: "When people are asked about ending aging, they often say the idea sounds nice, but they see no evidence for any actual progress toward ending aging in humans. They say that they've heard talk about that subject for years, or even decades, but wonder when all that talk is going to result in people actually living significantly longer. How do you respond?"Selected follow-ups:Aubrey de Grey on X (Twitter)The book Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our LifetimeThe Longevity Escape Velocity (LEV) FoundationThe SENS paradigm for ending aging , contrasted with the "Hallmarks of Aging" - a 2023 article in Rejuvenation ResearchProgress reports from the current RMR projectThe plan for RMR 2The RAID (Rodent Aging Interventions Database) analysis that guided the design of RMR 1 and 2Longevity Summit Dublin (LSD): 13-16 June 2024Unblocking the Brain's Drains to Fight Alzheimer's - Doug Ethell of Leucadia Therapeutics at LSD 2023 (explains the possible role of the cribriform plate)Targeting Telomeres to Clear Cancer – Vlad Vitoc of MAIA Biotechnology at LSD 2023How to Run a Lifespan Study of 1,000 Mice - Danique Wortel of Ichor Life Sciences at LSD 2023XPrize HealthspanThe Dublin Longevity Declaration ("DLD")Music: Spike Protein, by Koi Discovery, available under CC0 1.0 Public Domain Declaration

Dr. Aubry DeGrey Longevity specialist, author of Ending Aging and founder of LVEF.org explains to me the recent advances in allowing people to live longer and talks about some current projects. Please take a listen to this important message. @aubreydegrey @LongevityEVF http://levf.org/donate https://www.amazon.com/Ending-Aging-Rejuvenation-Breakthroughs-Lifetime/dp/0312367074

Dr. Aubry DeGrey Longevity specialist, author of Ending Aging and founder of LVEF.org explains to me the recent advances in allowing people to live longer and talks about some current projects. Please take a listen to this important message. @aubreydegrey @LongevityEVF http://levf.org/donate https://www.amazon.com/Ending-Aging-Rejuvenation-Breakthroughs-Lifetime/dp/0312367074Become a supporter of this podcast: https://www.spreaker.com/podcast/heartland-newsfeed-radio-network--2904397/support.

Dialogues In Longevity - A discussion with Dr. Aubrey de Grey & Dr. Michael Rose about the past, present and future of longevity biotechnology Host - Ira S. Pastor Special thanks to longevity advocate Eric Schulke (https://ruliaderic.wordpress.com/) for helping to organize and coordinate the episode - Dr. Aubrey de Grey, Ph.D., is President & Chief Science Officer of the Longevity Escape Velocity (LEV) Foundation ( https://www.levf.org/ ), an organization focused on proactively identifying and addressing the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease. Dr. de Grey is internationally recognized as a visionary biomedical gerontologist who devised the Strategies for Engineered Negligible Senescence: a comprehensive set of methods to rejuvenate the human body, thereby preventing age-related ill health and mortality. He has co-founded multiple non-profit organizations – including Methuselah Foundation, SENS Research Foundation, and now LEV Foundation – to specifically enable and accelerate its development and clinical translation. Dr. de Grey received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. He is the author of 'The Mitochondrial Free Radical Theory of Aging', 'Ending Aging', and a large number of academic papers. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the advisory boards of numerous scientific journals and research organizations. He is a prolific speaker who regularly presents at conferences and events world-wide. Dr. Michael Rose, Ph.D. ( https://www.faculty.uci.edu/profile/?facultyId=5261 ) is the Director of the Network for Experimental Research on Evolution (NERE), and Professor in the Department of Ecology and Evolutionary Biology at the University of California, Irvine, where his main area of work over the years has been the evolution of aging. He received his PhD from the University of Sussex in 1978. In 1991, Dr. Rose published seminal work per his text 'Evolutionary Biology of Aging' exploring a view of the subject based on antagonistic pleiotropy, the hypothesis that aging is caused by genes that have two effects, one acting early in life and the other much later. The genes are favored by natural selection as a result of their early-life benefits, and the costs that accrue much later appear as incidental side-effects that we identify as aging. Dr. Rose's laboratory has conducted the longest-running artificial selection experiment designed to test the theory of antagonistic pleiotropy using Fruit flies (Drosophila melanogaster) bred for longevity by collecting eggs from the longest-lived flies in each generation. The experiment has run since 1981, and has produced flies with quadruple the original life span. In 1997, Dr. Rose was awarded the Busse Research Prize by the World Congress of Gerontology. He has authored 10 books, including 'The Long Tomorrow: How Advances in Evolutionary Biology Can Help Us Postpone Aging'. Support the show

Michael Rae is the author with Aubrey De Grey of “Ending Aging”, and “is the author of five scientific articles and commentaries in peer-reviewed scientific journals. Much of his work has been devoted to elucidating... Source

Dr. Aubrey de Grey, Ph.D., is President & Chief Science Officer of the Longevity Escape Velocity (LEV) Foundation ( https://www.levf.org/ ), an organization focused on proactively identifying and addressing the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease. Dr. de Grey is internationally recognized as a visionary biomedical gerontologist who devised the Strategies for Engineered Negligible Senescence: a comprehensive set of methods to rejuvenate the human body, thereby preventing age-related ill health and mortality. He has co-founded multiple non-profit organizations – including Methuselah Foundation, SENS Research Foundation, and now LEV Foundation – to specifically enable and accelerate its development and clinical translation. Dr. de Grey received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. He is the author of The Mitochondrial Free Radical Theory of Aging (1999), Ending Aging (2007), and a large number of academic papers. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the advisory boards of numerous scientific journals and research organizations. He is a prolific speaker who regularly presents at conferences and events world-wide. Support the show

Aubrey David Nicholas Jasper de Grey is an English author and biomedical gerontologist. He is the author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007). He is known for his view that medical technology may enable human beings alive today not to die from age-related causes. As an amateur mathematician, he has contributed to the study of the Hadwiger–Nelson problem in geometric graph theory, making the first progress on the problem in over 60 years. De Grey is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies. He has been interviewed in recent years in a number of news sources, including CBS 60 Minutes, the BBC, The Guardian, Fortune Magazine, The Washington Post, TED, Popular Science, Playboy, The Colbert Report, Time, the Skeptics' Guide to the Universe, and The Joe Rogan Experience. He was the Chief Science Officer of the SENS Research Foundation. In late 2022, de Grey formed LEV Foundation as President and Chief Science Officer.This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/3240049/advertisement

Interesting interview about the future of Ageing with leading expert with Aubrey De Grey This week we interview the phenomenal Aubrey De Grey, the world's foremost authority on longevity and developing strategies to slow or eliminate aging altogether. The author of The Mitochondrial Free Radical Theory of Aging (1999) and Ending Aging (2007), De Grey is probably best known for the concept of Longevity Escape Velocity, a view that soon medical technology will enable human beings to prevent age-related deterioration, and eventually eliminated aging entirely. The future of Ageing with Aubrey De Grey Subscribe and listen to the Futurists Podcast where hosts Brett King and Robert Tercek interview the worlds foremost super-forecasters, thought leaders, technologists, entrepreneurs and futurists building the world of tomorrow. Together we will explore how our world will radically change as AI, bioscience, energy, food and agriculture, computing, the metaverse, the space industry, crypto, resource management, supply chain and climate will reshape our world over the next 100 years. Join us on The Futurists and we will see you in the future! Brett King is a world-renowned entrepreneur, futurist, speaker, international bestselling author, and media personality. China's President Xi Jinping cited his book Augmented: Life in the Smart Lane on the topic of Artificial Intelligence in his 2018 national address; the same book that was listed as a Top 10 non-fiction book in North America. In 2019 his book Bank 4.0 was awarded the Top Book by a Foreign Author in Russia for that year. Robert Tercek is an award-winning author, entrepreneur, and educator focused on the process of dematerialization and innovation. In his professional capacity, Mr. Tercek is a seasoned business executive with deep expertise in digital media and internet services. He is a prolific creator of interactive programs and products. He has designed and launched successful consumer experiences on every digital platform, including digital television, game consoles, broadband Internet, and mobile networks. In 2021, Mr. Tercek was recognized as the Humanitarian of the Year by the Media Excellence Awards for his leadership in designing and launching COVID SMART™, an interactive training program designed to keep workers safe on the job during the pandemic. See more reviews here. More about Irish Tech News Irish Tech News are Ireland's No. 1 Online Tech Publication and often Ireland's No.1 Tech Podcast too. You can find hundreds of fantastic previous episodes and subscribe using whatever platform you like via our Anchor.fm page here: If you'd like to be featured in an upcoming Podcast email us at Simon@IrishTechNews.ie now to discuss. Irish Tech News have a range of services available to help promote your business. Why not drop us a line at Info@IrishTechNews.ie now to find out more about how we can help you reach our audience. You can also find and follow us on Twitter, LinkedIn, Facebook, Instagram, TikTok and Snapchat.

The future of Ageing This week we interview the phenomenal Aubrey De Grey, the world's foremost authority on longevity and developing strategies to slow or eliminate aging altogether. The author of The Mitochondrial Free Radical Theory of Aging (1999) and Ending Aging (2007), De Grey is probably best known for the concept of Longevity Escape Velocity, a view that soon medical technology will enable human beings to prevent age-related deterioration, and eventually eliminated aging entirely. Subscribe and listen to the Futurists Podcast where hosts Brett King and Robert Tercek interview the worlds foremost super-forecasters, thought leaders, technologists, entrepreneurs and futurists building the world of tomorrow. Together we will explore how our world will radically change as AI, bioscience, energy, food and agriculture, computing, the metaverse, the space industry, crypto, resource management, supply chain and climate will reshape our world over the next 100 years. Join us on The Futurists and we will see you in the future! Brett King is a world-renowned entrepreneur, futurist, speaker, international bestselling author, and media personality. China's President Xi Jinping cited his book Augmented: Life in the Smart Lane on the topic of Artificial Intelligence in his 2018 national address; the same book that was listed as a Top 10 non-fiction book in North America. In 2019 his book Bank 4.0 was awarded the Top Book by a Foreign Author in Russia for that year. Robert Tercek is an award-winning author, entrepreneur, and educator focused on the process of dematerialization and innovation. In his professional capacity, Mr. Tercek is a seasoned business executive with deep expertise in digital media and internet services. He is a prolific creator of interactive programs and products. He has designed and launched successful consumer experiences on every digital platform, including digital television, game consoles, broadband Internet, and mobile networks. In 2021, Mr. Tercek was recognized as the Humanitarian of the Year by the Media Excellence Awards for his leadership in designing and launching COVID SMART™, an interactive training program designed to keep workers safe on the job during the pandemic.

This week we interview the phenomenal Aubrey De Grey, the world's foremost authority on longevity and developing strategies to slow or eliminate aging altogether. The author of The Mitochondrial Free Radical Theory of Aging (1999) and Ending Aging (2007), De Grey is probably best  known for the concept of Longevity Escape Velocity, a view that soon medical technology will enable human beings to prevent age-related deterioration, and eventually eliminated aging entirely.

Aubrey David Nicholas Jasper de Grey is an English author and biomedical gerontologist. He is the author of The Mitochondrial Free Radical Theory of Aging and co-author of Ending Aging. He is known for his view that medical technology may enable human beings alive today not to die from age-related causes. Become a member at https://plus.acast.com/s/unimpressedpodcast. https://plus.acast.com/s/unimpressedpodcast. Hosted on Acast. See acast.com/privacy for more information.

Most people think about Parkinson's disease as being just what it's called: a disease — a distinct clinical entity, which can be treated as a thing to itself. In fact, however, like all the other diseases of aging, it's the result of the lifelong accumulation of specific kinds of cellular and molecular damage that happen to all of us as part of the biological aging process. PD results from specific kinds of aging damage accumulating in key parts of the brain and nervous system, but similar damage accumulates in other aging tissues, causing dysfunction in those local tissues; these degenerative processes get labeled "diseases" when they reach a tipping point and the tissue can no longer carry out its normal function. The good news is that we now have a strategy for preventing, delaying, and one day even reversing Parkinson's and other diseases of aging through the revolution in rejuvenation biotechnology: therapies that directly remove, repair, replace, or render harmless the damage of aging. By clearing out that damage from the tissues, functionality can be restored and youthful health and vigor with it. SENS Research Foundation https://www.sens.org is a 501(c)3 medical research charity that is working hard to accelerate the development of a comprehensive suite of rejuvenation biotechnologies, to bring the benefits as soon as possible to as many people as possible. My guest today is Michael Rae, Science Writer at SENS Research Foundation, and coauthor with cofounder Dr. de Grey of "Ending Aging:" http://www.amazon.com/dp/0312367074 http://smile.amazon.com/dp/B01EBAP43C/  

BONUS EPISODES & EARLY RELEASES: https://www.patreon.com/auxoro Aubrey de Grey is a research scientist, author, and Chief Science Officer of the SENS Research Foundation.  Aubrey de Grey Links:Ending AgingSENS Research FoundationDonate to SENSSubscribe to SENS Newsletter Auxoro Links:InstagramFacebookTwitterTikTokYouTubeNewsletterPatreon (Bonus Episodes + Early Releases) 

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey will talk about the hallmarks of aging that he defined and more specifically about the stiffening of the extra cellular matrix a hallmark that was in his original list but not the 2013 paper. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about why SENS was founder and why the research that the foundation undertakes is not done by other organizations. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

In this episode of the Judgment Call Podcast – Aubrey de Grey and I talk about: 00:02:16 How Aubrey de Grey got into the ‘longevity research‘ in the first place?00:07:01 How Aubrey got the confidence to put a precise year to the ‘end of aging’.00:12:01 What were the biggest obstacles to overcome in persuading the public that ‘aging can be ended’00:13:30 Was setting up a money price for the extension of the lifespan of mice a good idea?00:21:10 Why the longevity industry is burgeoning at the seams suddenly?00:25:09 Will the benefit of an extended lifespan be equally available to a large part of the population?00:31:01 Once aging is solved will we see a population of 100 billion on earth?00:34:50 How Aubrey envisions life ‘past the Singularity’?00:38:30 How will our brains react to aging? Are there any drugs that we can use right now that may delay aging?00:42:01 Is the the FDA to blame for the slow innovation in the healthcare industry? Has COVID changed the regulatory environment? You may watch this episode on Youtube – The Judgment Call Podcast Episode #58 – Aubrey de Grey (Can we finally reverse aging ‘forever’?!). Aubrey de Grey is the Chief Science Officer of the SENS Research Foundation. He has been an evangelist of longevity research for decades. He is also the author of ‘Ending Aging‘. Big Thanks to our Sponsors! ExpressVPN – Claim back your Internet privacy for less than $10 a month! Mighty Travels Premium – incredible airfare and hotel deals – so everyone can afford to fly Business Class and book 5 Star Hotels! Sign up for free! Divvy – get business credit without a personal guarantee and 21st century spend management plus earn 7x rewards on restaurants & more. Get started for free! Brex – get a business account, a credit card, spend management & convertible rewards for every dollar you spend. Plus now earn $250 just for signing up (Terms & Conditions apply).

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about his view of what the future of aging will look like Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about his view on the latest rejuvenation technology. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about how the idea of an extended lifespan is being accepted by society and some of the implications of this. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey will talk about his view on the epigenetic aging clocks and their value in aging research. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey will talk about the hallmarks of aging that he defined and more specifically about the stiffening of the extra cellular matrix a hallmark that was in his original list but not the 2013 paper. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Aubrey de Grey is a biomedical gerontologist. He’s the co-founder and chief science officer of the SENS Research Foundation, which is a non-profit that does basic research on aging and treatments for aging. We start with the basics of aging, and some critical reactions to the notion that ageing could ever be overcome. Then Aubrey tells us about the seven types of damage that cause ageing and their corresponding repair technologies. I also ask him about the limits of model organisms in aging research. If at some point you’d like to skip to Aubrey talking about time estimates for ending aging and the effective altruism case for ending aging - you can skip approximately 1 hour and 32 minutes into the podcast.

Dr. Aubrey de Grey is a biomedical gerontologist based in Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) biomedical research charity that performs and funds laboratory research dedicated to combating aging. In addition, he is Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging.He received his BA in computer science and Ph.D. in biology from the University of Cambridge. His research interests encompass the characterization of all the types of self-inflicted cellular and molecular damage that constitute mammalian aging and the design of interventions to repair and/or obviate that damage.Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations. He is a highly sought-after speaker who gives 40-50 invited talks per year at scientific conferences, universities, companies in areas ranging from pharma to life insurance, and to the public.Topics Discussed:Brief overview of SENSWhy try to end aging?How soon do you think we will end aging?What role does rejuvenation biotech play in the COVID-19 pandemic? How would regenerative medicine help us better cope with the pandemic?How are you implementing the techniques you research in your own life?Which breakthrough are you most proud of?Aubrey's Links:LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/Personal Website: https://www.sens.org/Company Website: https://www.mfoundation.org/Twitter: https://twitter.com/aubreydegrey

Learn about the scientific breakthroughs that have unlocked the secret of aging. Ending Aging (2007) is a scientific exploration of aging and the factors which cause our bodies to decay. Founded on Dr. Aubrey de Grey’s groundbreaking research, this book demonstrates the new insights which have enhanced our understanding of the aging process and, consequently, what modern science can do to turn back the clock. *** Do you want more free audiobook summaries like this? Download our app for free at QuickRead.com/App and get access to hundreds of free book and audiobook summaries.

  Aubrey de Grey is an English author and biomedical gerontologist. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, Inc. He is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging (1999), and co-author of Ending Aging (2007). He is known for his view that medical technology may enable human beings alive today not to die from age-related causes. We will talk about his problem-solving skills, cutting edge anti-aging science, and what might happen if we were to live forever.  Some questions I ask: (03:47) How do you specifically tackle a huge problem? Do you have a procedure, or what do you do? (09:00) Why are you so optimistic that ending aging or increasing our lifespan might be right around the corner? (23:13) How long do you think it might take you to completely end aging? (29:35) Do you think that once this happens, people are going to start taking life for granted? (38:02) What’s your opinion on solutions that are solely for the sake of living longer like mind uploading?

Our conversation covers the importance of non-academic institutions in science, strategies for combating for repair the damage of aging, and an exploration of how extending human lifespan will change the Earth. In Dr. de Gray's perspective, age-related decline is a medical problem like any other that can be treated and cured by cutting edge technology. He's devoted himself to this pursuit as a founder of the SENS Research Foundation, the Methuselah Foundation, and the medical startup AgeX. Please subscribe to our channel so we can bring you more like this!!! Support Dr. de Grey & DS when you buy his books: Ending Aging: https://amzn.to/31Wyo4V Advocate for An Indefinite Human Lifespan: https://amzn.to/3kPHJUP SENS Foundation: https://www.sens.org Aubrey de Grey: https://twitter.com/aubreydegrey More readings from us: https://demystifyingscience.com Demystifying Science Mailing List: http://eepurl.com/gRUCZL Let's talk! @DemystifySci Twitter: https://twitter.com/demystifysci Instagram: https://www.instagram.com/demystifysci Facebook: https://www.facebook.com/demystifysci ~~~~~~~~~~~~~~ Music: ~~~~~~~~~~~~~~ Shilo Delay: https://soundcloud.com/laterisgone Blippy Trance by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/5759-blippy-trance License: http://creativecommons.org/licenses/by/4.0/ --- Support this podcast: https://anchor.fm/demystifying-science/support

Aubrey is the Chief Science Officer and Co-founder of the SENS Research Foundation and author of the book Ending Aging. He is working on undoing the damage of aging in order to help humans live much longer and healthier lives than most have ever imagined could be possible. -- Thank you for listening to Pod of Jake! All shares and reviews are appreciated! If you enjoy this podcast, you might like reading blogofjake.com If you prefer listening over reading, you might prefer Blog of Jake's blog on tape, available through any of your favorite podcast providers. Website: podofjake.com Twitter: @blogofjake Email: jake@blogofjake.com Call: superpeer.com/jake Support: patreon.com/blogofjake Bitcoin: 3ESGQxrJZmGqd2SifqCUiHPvah1uWtN1Zd

Learn about the scientific breakthroughs that have unlocked the secret of aging. Ending Aging (2007) is a scientific exploration of aging and the factors which cause our bodies to decay. Founded on Dr. Aubrey de Grey’s groundbreaking research, this book demonstrates the new insights which have enhanced our understanding of the aging process and, consequently, what modern science can do to turn back the clock. *** Do you want more free audiobook summaries like this? Download our app for free at QuickRead.com/App and get access to hundreds of free book and audiobook summaries.

Please join us as we sit down with Colin Milner, CEO of the International Council on Active Aging and founder of the active-aging industry in North America. Milner is also a leading authority on the health and well-being of the older adult, and has been recognized by the World Economic Forum as one of "the most innovative and influential minds" in the world on aging-related topics.An award-winning writer, Milner has authored more than 300 articles. He has been published in such journals as Global Policy, and the Annual Review of Gerontology and Geriatrics. He also contributed a chapter to the World Economic Forum book Global Population Ageing: Peril or Promise?Milner's speeches have stimulated thousands of business and government leaders, industry professionals & older adults worldwide.Whether Fortune 500 companies or governmental organizations, Milner's efforts have inspired a broad spectrum of groups to seek his counsel, include amongst these:World Health OrganizationWorld Economic Forum's Global Agenda Council on AgingOrganisation for Economic Cooperation and DevelopmentWhite House Conference on AgingUS Department of Health and Human ServicesUS Administration on AgingNational Institute on AgingAcademy of Nutrition and DieteticsThe Canadian Minister of State (Seniors) and (Finance)Canadian Special Senate Committee on AgingEuropean CommissionInformal Meeting of the European Union Ministers of SportNational Health Services - ScotlandWEF Think Tank: Preparing for Prosperous Longevity in AsiaWorld Economic Forum Expert NetworkingShanghai Forum4th International Strategy Conference on Safety and Health at WorkVancouver Olympic CommitteeBC Ministry of Healthy Living and SportDeloitte Life Sciences & Health CareErnst and YoungNew BalanceColin Milner received the CanFitPro Association "Lifetime Achievement Award" for his contributions to the Canadian fitness industry. He is also recognized as one Canada's Top 100 Health Influencers, and as a "Who's Who" in the US Fitness Industry. Milner's tireless efforts have leading-edge publications, television networks and radio stations seeking his insights. Among these outlets are: CNN, US News and World Report, Newsweek, Wall Street Journal, New York Times, Los Angeles Times, Chicago Tribune, Dow Jones Market Watch, Money Magazine, Entrepreneur Magazine, WebMD, The National Post, Globe and Mail, Parade Magazine, and Fox Business Radio.You can also enjoy this episode on our Podcast.BoomerLiving.tv website at: https://podcast.boomerliving.tv/active-aging-the-process-of-being-an-active-adult-with-colin-milner/You can enjoy more episodes at: https://podcast.boomerliving.tv/category/episodes/Please rate, subscribe, and share if you enjoyed this podcast episode.Colin Milner's Links:LinkedIn: https://www.linkedin.com/in/colinmilner/Twitter: https://twitter.com/colinmilnerInternational Council On Active Aging: https://www.icaa.cc/about_us/founder.htm

Scientists who study the biology of Aging agreed that we would someday be able to slow down the aging process substantially.Dr. Aubrey de Grey, Chief Science Officer at SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, believes that the critical biomedical technology required to eliminate aging derived debilitation and death is now within reach.In his book “Ending Aging” he and his research assistant Michael Rae described the details of this biotechnology. They explained that the aging of the human body, just like the Aging of manmade machines, results from an accumulation of various types of damage. As with manmade machines, this damage can periodically be repaired, leading to the indefinite extension of the machines fully functional lifetime just as is routinely done with classic cars.We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage.By demystifying aging, Dr. Aubrey de Grey systematically dismantles the fatalist presumption that aging will forever defeat the efforts of medical science.He is the author of “Ending Aging,” rejuvenation breakthroughs that could reverse human Aging in our lifetime. His book is available at Amazon.com: https://www.amazon.com/Ending-Aging-Rejuvenation-Breakthroughs-Lifetime/dp/B01EBAP43C/ref=sr_1_1?keywords=Ending+Aging+aubrey+de+grey&qid=1583555592&sr=8-1Aubrey's Links:LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/Personal Website: https://www.sens.org/Company Website: https://www.mfoundation.org/Twitter: https://twitter.com/aubreydegreyThis podcast is also available on Podcast.BoomerLiving.tv at the link: https://podcast.boomerliving.tv/ending-aging-by-reversing-human-aging-in-our-lifetime-with-dr-aubrey-de-grey-phd/

“Your future self is watching right now through your memories.”–Aubrey de Grey   The newly released volume, After Shock, features 50 of the world’s most renowned futurists reflecting on the 50-year legacy of Alvin Toffler’s Future Shock, and looking ahead to the next 50 years.  Seven of the contributors have been guests on Seeking Delphi™  This is […]

Meet Aubrey De Grey – Chief Science Officer at SENS Research Foundation, VP of New Technology Discovery at AgeX Therapeutics, and editor-in-chief of Rejuvenation Research, the highest-impact peer-reviewed academic journal focused on postponing aging. He works on the development of medical innovations that can postpone all forms of age-related ill-health with an undivided focus is on rejuvenation: that is, the active repair of the various types of molecular and cellular damage which eventually cause age-related disease and disability, as opposed to the mere retardation of the accumulation of such damage. Our guest tells his story of how he came to be a biologist from being destined to be a pianist according to his mother in the beginning and later choosing programming out of a wish to make more of a contribution to the progress of mankind. Insights Switching fields and how it helped Aubrey find fulfilment in his work. Understanding the process of aging – how it happens and what is the rational, sustainable, and effective way to combat it. Why public awareness on the topic is important, and how Aubrey has been striving to raise awareness. What makes us age faster is not just the unhealthy habits of ours, but also the mechanisms like breathing that are essential to our life. Whether fasting helps you combat the aging process or not. A revolutionary view in gerontology and how it became mainstream, thanks to Aubrey's untiring efforts. Where we hope to be in the coming decades in terms of defeating the process of aging altogether or even partially. Why individual contributions are important in the field of gerontology. Aubrey and his foundations Connect on LinkedIn - https://www.linkedin.com/in/aubrey-de-grey-24260b/ - SENS Research Foundation - https://www.sens.org/ The Methuselah Foundation - https://www.mfoundation.org/ ABOUT THE HOST My name is Sam Harris. I am a British entrepreneur, investor and explorer. From hitchhiking across Kazakstan to programming AI doctors I am always pushing myself in the spirit of curiosity and Growth. My background is in Biology and Psychology with a passion for improving the world and human behaviour. I have built and sold companies from an early age and love coming up with unique ways to make life more enjoyable and meaningful. Sam: Instagram (https://www.instagram.com/samjamsnaps/) Quora (https://www.quora.com/profile/Sam-Harris-58) Twitter (https://twitter.com/samharristweets) LinkedIn (https://www.linkedin.com/in/sharris48/) Sam's blog - SamWebsterHarris.com (https://samwebsterharris.com/) Support the Show - Patreon (https://www.patreon.com/growthmindset) Sponsor - Feals (https://feals.com/growth) Feals has me feeling my best every day and it can help you too.  Become a member today by going to Feals dot com slash growth and you'll get 50% off your first order with free shipping.  That’s F-E-A-L-S dot com slash growth to become a member and get 50% automatically taken off your first order with free shipping.  Feals dot com slash growth. Summary Aubrey's Career Path "I wanted to be a scientist, but ultimately, I wanted to make a difference to the world. And I recognized that scientists, in the long run, make the most difference.” Having chosen programming at the age of 15 and for the purpose of making more of a difference to the world, Aubrey continued in that career till he got exposed to something much more demanding. "I started programming, and I thought that one of the biggest problems the world faces is that people have to spend so much of their time doing stuff that they wouldn’t do unless they were being paid for it – I’ll stop that by helping in artificial intelligence research to create more automation. ” Learn why Aubrey chose to switch fields back in 1990 and pursue a career that could ultimately fulfil his desire of being able to make as big of a difference to the world as possible. "Having found out that nobody was working on trying to keep people healthy late in life – not properly, anyway – I thought, what? I better switch fields, really? And that’s what led to my moving into the biology of aging back in the early 1990s. ” https://images.unsplash.com/photo-1566669437687-7040a6926753?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=667&q=80 Raising Awareness and Concern about the Process of Aging Our guest is the person who played a key role in the introduction and spreading of this revolutionary idea in the field of gerontology – a switch from making efforts for the prevention of ‘aging’ to making efforts for the remediation of the process called ‘aging.’ "I was fortunate enough to have a few ideas in the late 90s that were quite well received, so I rose to great prominence in gerontology very quickly. In the year 2000, I had the idea that comprehensive damage repair is the most promising and practical way to keep people healthy late in life. ” "My goal is and has always been to grow this movement to a point that I become unnecessary, that there are people in the field who are better than me. And then I will retreat into glorious obscurity. ” https://images.unsplash.com/photo-1519171920866-a020bf47357b?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=750&q=80 A New Concept in Gerontology It took him much and more to make people realize that not only do they want to live, but they also want to live long and live healthy – that eventually leads to the idea that they want to defeat the biologically deteriorative process called aging. "If it’s all about simple health care and if one recognizes that longevity is simply a side effect of not getting sick, then the argument becomes a great deal easier to make. ” Learn why defeating aging is more about reducing the combined effect of time on biological systems than trying to prevent that effect from occurring at all. "The most common sense and most practical approach to keeping people healthy late in life was simply to repair the damage that the body does to itself throughout life, not necessarily perfectly, but well enough so that the overall amount of damage that remains in the body is within the capacity of the body to tolerate. ” https://images.unsplash.com/photo-1505682614136-0a12f9f7beea?ixlib=rb-1.2.1&auto=format&fit=crop&w=751&q=80 Striving for the Cause Aubrey has contributed much and more to the spreading of awareness about all these concepts because that is how the scientists can motivate people from all domains to donate and contribute to the progress of research that eventually benefits the whole of mankind. "If you’re working on something that is interesting and important, it’s not such a problem to get people to come and work for you.” https://images.unsplash.com/photo-1522211988038-6fcbb8c12c7e?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=750&q=80 Having an Understanding in Multiple Fields Learn how switching fields is one of the most innovative and productive things that can happen in one’s career. It opened a whole new dimension for Aubrey, and it also allows for a profitable transfer of skill sets from one domain to another. "It’s quite clear that when people switch fields, they very often do really good things in the new field because they’ve got the skill set to work on really hard problems because of their transferable skill, but they’re not encumbered by the conventional wisdom that everybody else in the field have.” https://images.unsplash.com/photo-1546188994-07c34f6e5e1b?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=751&q=80 Hope for the Future Aubrey has high hopes for the future of gerontology and welcomes any feedback or help that people have to offer him on his way to the achievement of these universal goals. "I think within the next 10 years, we will have reached the threshold of research that I historically have called robust master rejuvenation. It’s only a matter of time before we can bring aging under comprehensive medical control.” He also believes that only a collective effort can uproot the problem altogether. "I believe that at the end of the day, this problem of aging will not be solved by one person or one organization. It will be a collective effort because it should divide and conquer approach.” https://images.unsplash.com/photo-1478796415026-3c85ee65975e?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=750&q=80 Moving Forward Aubrey is trying to get people to move past all the obstacles that are stopping them from being concerned about aging. Any contribution to the movement that he has initiated is much appreciated. "It’s all about past people’s fear of getting their hopes up and knowing that people have been wrong about the defeat of aging right through the history of civilization.” Subscribe! If you enjoyed the podcast please subscribe and rate it. And of course, share with your friends! Special Guest: Aubrey De Grey.

Aubrey de Grey is the most famous expert in the world on ending aging, founder of SENS foundation and a real-life Gandalf.

This episode will take you through Dr. Aubrey de Grey’s Seven Pillars of aging, the research that he's currently doing, his opinion on biological age, AGEs and the different sources, and the impact of growth hormone on biological age.Who is Dr. Aubrey de Grey?Aubrey de Grey is an English author and biomedical gerontologist. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, Inc.He is the editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging and co-author of Ending Aging. He is known for his view that medical technology may enable human beings alive today not to die from age-related causes.He is also an amateur mathematician who has contributed to the study of the Hadwiger–Nelson problem.His research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage. De Grey is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies.He has been interviewed in recent years in a number of news sources, including CBS 60 Minutes, the BBC, The New York Times, Fortune Magazine, The Washington Post, TED, Popular Science, The Colbert Report, Time, the Skeptics' Guide to the Universe, and The Joe Rogan Experience. He is also a member of Flooved advisory board.Highlights[1:57] Where are we in the battle against aging?[4:29] Dr. de Grey explains the seven aspects of aging[8:38] Effects of lifestyle on the AGEs and aging[12:23] Measures for biological age[18:07] Why haven’t we evolved past aging?[20:28] Alzheimers, cancer and cardiovascular disease as components of aging[24:44] Transitioning from computer science to gerontology[27:53] Dr. de Grey answers the Superhuman sixResourcesThe Health Optimisation SummitHorvath’s Epigenetic clockReversing Biological Age by Greg FahyEnding Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our LifetimeOur sponsor today is CAR.O.L You don’t have time for that 45 minute jog.You need something fast, efficient, and leaves you wanting more. My favorite tool for this is the CAR.O.L. She is a life-changing bike, that provides you all the endurance you need into two 20 second bursts. Yes, you read that right. That’s 40 seconds of max-effort, including the warm up and cool downs, you get a kick-ass workout in 8 minutes and 40 seconds. The CAR.O.L is a resistance bike powered by artificial intelligence, which personalizes and optimizes the resistance, so you hit your maximum intensity levels and maximize glycogen depletion every single time. The proof is really in the pudding. CAR.O.L’s effectiveness was independently verified by the American Council on Exercise. I gave the CAR.O.L bike spin at Health Optimization Summit in London this year, and she kicked my ass so much that I had to get one. Check out CAR.O.L at carolfitai.com If you have limited time and want an amazing workout, which basically everyone that listens to this show does, use the code DECODING150 for a big discount, head over to CarolfitAI.com to secure yours.Continue Your High Performance Journey with Dr. de GreyWebsiteTwitterDisclaimer This information is being provided to you for educational and informational purposes only. This is being provided as a self-help tool to help you understand your genetics, biodata and other information to enhance your performance. It is not medical or psychological advice. Virtuosity LLC, or Decoding Superhuman, is not a doctor. Virtuosity LLC is not treating, preventing, healing, or diagnosing disease. This information is to be used at your own risk based on your own judgment. For the full Disclaimer, please go to (Decodingsuperhuman.com/disclaimer). See acast.com/privacy for privacy and opt-out information.

Ending Aging: Living Beyond 130 Years - Yuri Deigin   In this episode, Yuri discusses new scientific breakthroughs in Aging. Can Stem cells and Yamanaka factors be the key to stopping aging? Can we use Crisper technology to reverse the age of the cell and much more!    "Shinya Yamanaka has shown that an adult cell can be 'reprogrammed' back to embryonic state by OSKM transcription factors. Later research has shown that cells also undergo considerable rejuvenation in the process of reprogramming."   Guest Yuri Deigin, MBA   http://youthereum.io       Yuri is a serial entrepreneur, an expert in drug development and venture investments in biotechnology and pharmaceuticals. Yuri brings almost a decade of drug discovery and development experience from his previous role in a biotech startup where he oversaw research and development of original medicines aimed at treating diseases like Alzheimer's and rheumatoid arthritis. Yuri has a track record of not only raising over $20 million for his previous ventures but also initiating and overseeing 4 clinical trials and several pre-clinical studies, including studies in transgenic mice. He also has experience in pharmaceutical product launch, promotion, manufacturing and supply chain management. Since 2013 Yuri also serves as a vice-president of the non-profit Foundation "Science for Life Extension" whose goal is the popularization of the fight against age-related diseases. To further this cause, Yuri frequently blogs, speaks, writes op-ed pieces, and participates in various TV and radio shows. Yuri holds a B.Sc. from the University of Toronto and an M.B.A. from Columbia Business School.

Aubrey De Grey is known for his view that medical technology may enable human beings alive today not to die from age-related causes. He is also an amateur mathematician who has contributed to the study of the Hadwiger–Nelson problem.His research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage.--- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Aubrey De Grey is known for his view that medical technology may enable human beings alive today not to die from age-related causes. He is also an amateur mathematician who has contributed to the study of the Hadwiger–Nelson problem. His research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process. Today's guest is perhaps the most bullish of all such researchers and believes that the key biomedical technology required to eliminate aging-derived debilitation and death - is now within reach. In his book, he and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to the indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, our guest systematically dismantles the fatalist presumption that aging will forever defeat the efforts of medical science. We welcome the author of Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime Dr Aubrey de Grey. We discuss: The Sens Mission to end age The challenges of changing the age paradigm Decoupling aging from age-related diseases The 7 common age-related diseases The 7 solutions to those diseases The impact of immortality of society More about Aubrey and Sens here: https://www.sens.org

Although Aubrey practices biology, he started his career as a computer scientist. He worked several years after obtaining his computer science degree on Artificial Intelligence (AI). During that time he met a marine biologist and discovered that biologists, in general, were not interested in aging. Since then, he studied and has been working around the biology of aging.

This week on the show I chat with Mark Katakowski and Steven Clausnitzer of ForeverLabs. ForeverLabs is a Y Combinator company that helps people live longer by offering stem cell banking and storage.  In this episode, we'll chat talk about the book that inspired Mark and Steven to start the project (Ending Aging by Aubrey de Grey) as well as how ForeverLabs works (How do you get started banking your stem cells? Is it safe?). And I'll share my experience having my stems cells banks last week using ForeverLabs.  Learn more about ForeverLabs here: https://foreverlabs.com/ Details of my experience are online at: https://castig.org/how-i-banked-my-stem-cells/  And.....

Today we explore human longevity and life extension efforts focused on adding healthy years to a person's lifespan, and even reversing the aging process.   My guest is Dr. Aubrey de Grey, a leading voice in the field and the Chief Science Officer of the SENS Research Foundation which is doing pioneering work on significantly extending healthy, active lifespans. Aubrey is a biomedical gerontologist with a degree in Computer Science and a Ph.D. in Biology. He is author of the book "Ending Aging" and Editor-in-Chief of the scientific journal "Rejuvenation Research".   Aubrey sees life extension as a side effect of his efforts to make people healthier, and sees no inherent limit to how far this could ultimately extend. We explore such concepts the "pro aging trance", "longevity escape velocity" and "comprehensive damage repair" that can sustain a human body.   More on Aubrey and the SENS Research Foundation: https://www.sens.org   More at: https://www.MindAndMachine.io

Are you interested in space travel, genetic engineering and other futurist tech trends transforming our world/society? If so you will love this.Our Expert Panelists:Aubrey de Grey is a Cambridge researcher and Chief Science Officer of SENS Research Foundation focused on aging and extending human longevity. He proposes that the first human beings who will live to 1,000 years old have already been born. In addition to his research, Aubrey is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging(2007). De Grey’s research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls “Strategies for Engineered Negligible Senescence” (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage.Mike Selden is co-founder and CEO of Finless Foods, a food startup that uses cutting-edge cellular-agriculture technologies to grow marine-animal cells, creating fish and seafood products enjoyed around the world. They are working toward a sci-fi, soon-here world where everyone has access to healthy, delectable seafood, without the environmental devastation or the health hazards of traditional fishing and aquatic farming.Jenny Rooke is the founder and managing partner or Genoa Ventures (formerly 5 Prime Ventures) where she funds and builds companies that change the way science gets done with new tools and technologies. She has a PhD in Genetics, a Bachelors in physics, and a background in computer science and works closely with early-stage life science start-ups on issues of fundraising, market and product strategy, and business development.We cover a wide range of topics from genetic engineering and human longevity to personalized medicine, pharma, manufactured meats and much more...You can listen right here on iTunes--Make a Tax-Deductible Donation to Support FringeFMFringeFM is supported by the generosity of its readers and listeners. If you find our work valuable, please consider supporting us on Patreon, via Paypal or with DonorBox powered by Stripe.Donate

Aubrey de Grey (@aubreydegrey) is Cambridge researcher and Chief Science Officer of SENS Research Foundation focused on aging and extending human longevity. He proposes that the first human beings who will live to 1,000 years old have already been born.In addition to his research, Aubrey is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007).  De Grey's research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage.He has been interviewed by most major news sources, including CBS 60 Minutes, the BBC, The New York Times, Fortune Magazine, The Washington Post, TED, Popular Science, The Colbert Report, Time and the Skeptics' Guide to the Universe.You can listen right here on iTunesIn our wide-ranging conversation, we cover many things, including: * Why Aubrey switched from studying AI to the science of human longevity * The causes of aging and how we can "cure" them * Why prevention is orders of magnitude more effective than intervention * The reason Aubrey believes some humans today will live to be 1000 years old * Why there isn't enough funding or support currently for fighting aging * The reason stem cell research is progressing rapidly and proving fruitful * How caloric restriction effects metabolism and aging * Why SENS often spins out businesses to further their aims * The science of immortality * How mainstream media has reacted to prospect of increasing lifespanTranscriptProducing this podcast and transcribing the episode takes tons of time and resources. If you support FringeFM and the work we do, please consider making a tax-deductible donation. If you can’t afford to support us, we completely understand as well, but an iTunes review or share on Twitter can go a long way too! AUBREY DE GREY:  Well I do think it’s very probable. In fact, I think it’s quite likely that the first person to live to a thousand is already in their forties or fifties—or, and perhaps even older.  So the question is, “Why do I think that?” And a lot of people misunderstand this. Some people think that the reason I’m saying this is because I think that we are within a small number of decades of developing therapies that completely, one hundred percent eliminate aging by repairing every single aspect of the damage that the body accumulates as  a side effect of its normal operation. I don’t say that at all. I never have, and I never shall.  MATT:  Survival of the fittest—Darwin realized evolution is merely the process of survival.  Nothing has been more driving a force as survival. Nothing wants to die. I don’t want to die.  You don’t want to die—even if you’ve accepted death. When there’s a way around it, we would give anything.  Today we’ve got Aubrey de Grey. Aubrey’s the Cambridge researcher and chief science officer of th...

Aubrey de Grey is a biomedical gerontologist, and the Chief Science Officer of SENS Research Foundation, a California based non-profit charity dedicated to combating the aging process. Through his work at SENS, Aubrey works on the development of medical innovations that promote rejuvenation and can postpone all forms of age-related ill-health including diseases like alzheimers, certain forms of cancer and atherosclerosis. Aubrey started off as a computer scientist and AI Researcher before becoming a self-taught bio gerontologist, which makes him a fascinating example of someone who can pick up new skills and develop deep knowledge in new fields In this conversation we discuss: - The transferability of research as a skill and the multidisciplinary nature of innovation - The core ideas behind Aubrey’s research – and what that means for the future of human aging - How to successfully spread your message to attract interest to your work Aubrey has a love for bold statements and is often a magnet for controversy in the media, but he’s a remarkably flexible and original thinker, so whether you're curious about the future of human aging or want to learn more about how to communicate effectively in a world full of noise, this episode has you covered.

Phil and Stephen continue their discussion with Dr. Aubrey de Grey, reviewing some of the very encouraging life extension research currently taking place How does the treatment of other conditions (cancer, diabetes, obesity, heart disease, etc) ultimately contribute to the first generation of anti-aging medicine?Will devices such as those created for the Qualcomm Tricorder X Prize be a game-changer for treating aging? What role will CRISPR technology play in helping us to live longer?Metformin -- miracle youth drug or a lot of hype?Of the seven kinds of cell damage that constitute aging, which are we gaining on with the current research?And which is the most challenging? About Our Guest: Dr. Aubrey de Grey is a biomedical gerontologist who researched the idea for and founded the SENS Research Foundation. SENS stands for “Strategies for Engineered Negligible Senescence,” an idea that Aubrey outlined in his 2007 book, Ending Aging. Aubrey has a BA in Computer Science and a Ph.D. in Biology from the University of Cambridge. He is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations. He is also a contributor to our book Visions for a World Transformed. WT 327-636

Phil and Stephen welcome life extension researcher and visionary Dr. Aubrey de Grey to discuss the sometimes puzzlingly negative views much of the public seem to have about efforts to fight aging. Topics: A question Aubrey raises in Visions for a World Transformed:  What possesses people to defend the existence of the phenomenon that is far and away the most likely thing to kill them – and not only that, but to do so slowly and painfully? How is it that the elderly are themselves guilty of ageism? Glenn Reynolds in USA Today What is the pro-aging trance? Methuselah Mouse project as proof of concept for fighting aging Is life extension becoming more mainstream?  Is the first human being who will live to the age of 1,000 already among us? About Our Guest: Dr. Aubrey de Grey is a biomedical gerontologist who researched the idea for and founded the SENS Research Foundation. SENS stands for “Strategies for Engineered Negligible Senescence,” an idea that Aubrey outlined in his 2007 book, Ending Aging. Aubrey has a BA in Computer Science and a Ph.D. in Biology from the University of Cambridge. He is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations. He is also a contributor to our book Visions for a World Transformed. WT 326-635  

Crystal Society (or read it for free) Crystal Mentality Quick Links: Aubrey de Grey’s TED talk on extreme longevity Ending Aging – Aubrey de Grey’s book “The Sequences” – Compiled in book form. Max Harms on Cryonics (Video)  Micromort – The unit used … Continue reading →

Sex & Science Hour - S03 EP03: "Happy Dunky Dory" This is Episode 3 of Season 3 of Sex & Science Hour, with Brian Sovryn and Dr. Stephanie Murphy! Let the incendiary comments begin! Show Notes and Links: Segment 1 --"Smart Dumb: Samsung Washing Machines" Link: http://bit.ly/2eISgih --Promo: "Ending Aging": http://amzn.to/2fqUpPB Segment 2 --"The First Woman To Put Her Face On A Product Got Trolled!" Link: http://bit.ly/1Obn9q6 Segment 3 --Listener Question: "How To Not Do Jealous Boyfriend Rage" --"7 Reasons So Many Guys Don't Understand Sexual" Link: http://bit.ly/2fhG4pr After Show --"Your Amazon link purchases, City On the Edge of Forever, little black books, and more!" =================================================== Add the show to your favorite podcast app: http://feeds.soundcloud.com/users/soundcloud:users:77801291/sounds.rss =================================================== Email us feedback, comments, show prep, and relationship questions: show@sexandsciencehour.com =================================================== Love the show? Donate to us with Bitcoin: 1DNFqNvrKNBbFPux8PVFBUjmgwdZErHd9 =================================================== Shopping at Amazon? Use the SASH link! Just head to: http://stuff.sexandsciencehour.com =================================================== Awesome chiptunes that you heard in the show are by rolemusic! Hit the link: http://rolemusic.sawsquarenoise.com =================================================== Social Media Links: http://sexandsciencehour.com https://twitter.com/sexsciencehour https://instagram.com/sexandsciencehour https://soundcloud.com/sexandsciencehour =================================================== Thanks for tuning in!

Today, we are joined by Aubrey de Grey, biomedical gerontologist and Chief Science Officer of the SENS research foundation, and co-author of the book Ending Aging. You might know Aubrey from his appearances on 60 minutes, the BBC, The New York Times, Fortune, the Colbert Report, or his popular TED Talk. If you've heard him speak before, you'll know that he is one of the chief drivers behind the view that medical technology may one day enable people alive today to live… well, forever. Through his research on regenerative medicine, and what he calls “Strategies for Engineered Negligible Senescence, or SENS,” de Grey has proposed a number of ways to not only slow, but even stop and reverse the effects of age on the human body. During the episode, we talk about these methods, the effects of aging, and also raise some of the ethical and practical issues surrounding the idea of a-mortality. We talk about learning, and I was just blown away by how much knowledge and expertise my guest has accumulated - and how he has accumulated it. We also have an absolutely fascinating and engaging conversation about the potential of the future, and what humanity may look like in 20 or 30 years. We truly dive into the idea of what it might be to be “superhuman,” and the resulting conversation will definitely blow your mind. For those of you who really love the heavy, sciencey episodes where we geek out on technical terms, you're really going to love this episode, and for those of you who don't, well, you're going to learn a whole hell of a lot about your body and how it ages, and I'm quite sure you'll get a kick out of my guest's combination of jaw dropping wit and dry British humor.

Dr. Aubrey de Grey is a biomedical gerontologist who is the Chief Science Officer and Cofounder of SENS Research Foundation found at Sens.org. They work to extend the lifespan significantly. They believe the first person that will live to 1000 is alive today. He received a degree in  Computer Science and Ph.D. in Biology from the University of Cambridge. Dr. de Grey is Editor-in-Chief of Rejuvenation Research  and sits on numerous scientific advisory boards and journals. He is the author of  “Ending Aging”.   http://www.inspiredinsider.com/aubrey-de-grey-endaging-interview/  

Join Dr. Dan as he welcomes professor Aubrey de Grey. Dr. de Grey is the Chief Science Officer of the SENS Research Institute and is a leader in the field of longevity. He feels that human life has the potential to be extended 100's of years while maintaining youthful physiology. He is also featured in the critically acclaimed documentary: The Immortalists. Topics discussed: Is substantially extended human life-span possible? Will we see it in our lifetime? What technologies are necessary to get there? Where are we currently?

Aubrey De Grey is fighting the deadliest cause of death in the world. It kills two thirds of all people, far more than all other forms of death combined, and yet very little attention is given to curing it or solving it. That’s because unlike malaria or cancer or car accidents, people believe that aging is natural. This belief, which Dr. De Grey refers to as the pro-aging trance is the real barrier to combatting aging. In this episode, we focus on Dr. De Grey’s book, Ending Aging. Previously a researcher in the field of Artificial Intelligence, Dr. De Grey brings a unique perspective to the problem of aging. He approaches it as an engineering problem and in his book lays out the seven basic engineering problems that need to be solved in order to bring about the slowing and reversal of aging. In particular, we take a close look at the problem of mutations in mitochondrial DNA and how engineering can overcome this challenge. If you want to end aging, you can donate money to Dr. De Grey’s foundation http://sens.org/donate. It might be the best gift you can give your future self. Ending Aging is available on Amazon. You can follow Dr. De Grey on twitter at @aubreydegrey. By the end of this episode, we’ll be sure you’re convinced as we are that the biggest barriers to ending aging are not technological, they’re psychological.

Aubrey de Grey, PhD, is a biomedical gerontologist and Chairman and Chief Science Officer of The Methuselah Foundation. His major research interests are the role and etiology of all forms of cellular and molecular damage in mammalian aging, and the design of interventions to reverse the age-related accumulation of such damage. He has published extensively on these and other areas of gerontology, and is also Editor-in-Chief of Rejuvenation Research, the only peer-reviewed academic journal focusing on intervention in aging. He is the organiser of an ongoing series of conferences and workshops that focus on the key biomedical research relevant to SENS, and he also oversees the Methuselah Foundation's growing sponsorship of SENS research worldwide.In this conversation with D.J. Grothe, Aubrey de Grey explains aging, and the SENS (Strategies for Engineered Negligible Senescence) program that seeks to reverse aging in our lifetime. He explains how his work is, and is not, continuous with "transhumanism." He addresses challenges the medical and scientific establishment have brought against his work, and how his project is different than the quackery so widespread in the anti-aging movement. He also discusses some of the social and existential problems that ending aging may create for our civilization.