Podcasts about sens research foundation

Evgeny Lebedev joins Dr Aubrey de Grey, a pioneer in biomedical gerontology - the study of life extension and rejuvenation - and co-founder of the SENS Research Foundation.Known for his radical approach to ageing, Dr de Grey discusses his latest research, society's attitude to the human lifespan and his hopes for future anti-ageing treatments. Hosted on Acast. See acast.com/privacy for more information.

Evgeny Lebedev joins Dr Aubrey de Grey, a pioneer in biomedical gerontology - the study of life extension and rejuvenation - and co-founder of the SENS Research Foundation.Known for his radical approach to ageing, Dr de Grey discusses his latest research, society's attitude to the human lifespan and his hopes for future anti-ageing treatments. Hosted on Acast. See acast.com/privacy for more information.

Evgeny Lebedev joins Dr. Aubrey de Grey, a visionary in biomedical gerontology and co-founder of the SENS Research Foundation.Known for his radical approach to ageing, Dr. de Grey discusses why some need to awaken from a "pro-ageing trance".What's Aubrey's biological age?In this episode:Why we don't “have” to ageReversing cellular agingThe ethical questions surrounding life extensionThe societal shifts we might expect if ageing becomes a treatable conditionThe science behind extending the human healthspanPlus more. Hosted on Acast. See acast.com/privacy for more information.

In this episode of the Longevity Optimization Podcast, Dr. DeGray discusses groundbreaking research in aging and longevity, focusing on combination therapies, the hallmarks of aging, and the potential of stem cell and gene therapies. He emphasizes the importance of rejuvenation over merely slowing aging and explores the role of the immune system in health. The conversation also touches on biological age testing, lifestyle factors, and the future of gene therapy in enhancing longevity. Aubrey de Grey is a British biomedical gerontologist and the founder of the SENS Research Foundation. He is a leading advocate for regenerative medicine, focusing on reversing the effects of aging by repairing cellular damage. Known for his bold vision of life extension, de Grey believes that with advanced therapies, humans could significantly extend their lifespan. He is the co-author of Ending Aging, and his work continues to shape the future of longevity science. Takeaways Combination therapies are crucial for understanding aging. Rejuvenation may be easier than slowing down aging. Stem cell therapies hold great promise for the future. The immune system plays a significant role in aging. Biological age testing can provide insights into health. Gene therapy is a promising avenue for longevity research. Lifestyle factors have limited impact on lifespan extension. Understanding the hallmarks of aging is essential for interventions. Preventative maintenance is key to longevity. The future of aging research is bright with new technologies. Chapters 00:00 Introduction to Longevity and Aging Research 02:50 Combination Therapies in Aging Research 05:57 The Hallmarks of Aging 09:12 Interventions for Rejuvenation 11:57 Stem Cell Therapies and Their Future 15:03 The Role of the Immune System in Aging 17:56 Insights on Aging and Rejuvenation 20:47 Biological Age Testing and Its Implications 24:01 The Future of Gene Therapy in Aging 26:49 Lifestyle Factors and Aging 30:04 Conclusion and Final Thoughts Learn more about Aubrey's work: https://www.levf.org Visit Kayla's website: KaylaBarnes.com

They say aging is just a part of life, but have you ever wondered if it really has to be? What if getting older isn't just something we accept but something we could actually treat?    In this riveting episode of Peak Human Labs Podcast,  Dr. Sanjeev Goel, sits down with Dr. Aubrey de Grey, a trailblazing biomedical gerontologist and Chief Science Officer of the SENS Research Foundation. They dive deep into the revolutionary idea of treating aging as a medical condition. They explore how damage accumulates in our bodies over time and discuss the groundbreaking medical advancements that could extend our healthy lifespans. Dr. de Grey sheds light on the crucial need for investing in underfunded research and shares insights into the future of longevity science. Tune in and envision a future where health and longevity are not just aspirations but achievable realities!   Click HERE to sign in for Dublin Longevity Declaration. Key Takeaways   Aging as a medical condition versus a natural process Mechanisms of damage accumulation in the body Concept of "longevity escape velocity" Role of epigenetic changes in aging Importance of comprehensive interventions targeting different types of damage Current state of therapies for extending human lifespan Economic implications of aging therapies and preventative medicine Research on retroviruses and chronic infections in relation to aging Innovative therapies such as hyperbaric oxygen therapy and therapeutic blood exchange The significance of personalized health approaches and the microbiome's impact on longevity   In This Episode:   [00:00:00] Introduction to longevity research [00:00:51] Guest introduction [00:01:17] Personal connection [00:02:04] Dr. de Grey's background [00:03:14] Early research stages [00:04:05] Understanding aging as a machine [00:05:22] Accumulated damage mechanism [00:06:15] Comprehensive medical control [00:07:13] Categories of damage [00:07:55] Wear and tear concept [00:09:20] Epigenetic changes discussion [00:11:31] Partial reprogramming concept [00:13:30] Addressing multiple mechanisms [00:14:31] Longevity escape velocity [00:15:43] Initial pushback on longevity ideas [00:17:51] Positive outlook on aging research [00:19:51] The future of longevity research [00:20:54] Funding disparities in research [00:21:10] Business models in longevity research [00:21:58] Combining existing therapies [00:23:47] Current longevity therapies [00:24:56] Caloric restriction vs. drugs [00:25:36] Dublin Longevity Declaration [00:26:39] Community building through conferences [00:28:09] Anticipating longevity breakthroughs [00:29:12] Access to longevity therapies [00:30:58] Epigenetic clocks and age reversal [00:32:24] Retroviruses and aging [00:34:56] Persistent viral infections [00:37:24] Hyperbaric oxygen therapy [00:37:49] Therapeutic blood exchange [00:39:37] Discussion on active ingredients [00:40:41] Bone marrow transplant experimentation [00:42:09] Health benefits of bone marrow transplants [00:43:05] Personal health practices [00:43:55] Advice for maximizing healthy lifespan [00:45:01] Microbiome and longevity   Notable Quotes [00:03:14] "The idea that anyone could ever think that aging was just something we should accept has never made any sense to me at all." — Dr. Aubrey de Grey   [00:14:31] "I believe we need to get to about 20 years of postponement of the health problems of late life, which I think we might be able to achieve in the next 12 to 15 years." — Dr. Aubrey de Grey   [00:25:36] "Not only are they my favorite parts of the year, but also they are absolutely the fulcrum, the centerpiece of all of my community building effort." — Dr. Aubrey de Grey   [00:43:36] "I can eat exactly what I like and nothing ever happens, and I don't even need to do any exercise and I still stay fit, so you know, don't do as I do, do as I say." — Dr. Aubrey de Grey   [00:43:55] "Everybody's metabolism has its own strengths and weaknesses, and so honestly, the only generic advice that I feel that one can give in terms of maximizing one's healthy lifespan is to pay close attention to your body." — Dr. Aubrey de Grey   [00:44:28] "I honestly can see a strong argument for just recommending to absolutely everybody that they should eat gluten-free food for like a fortnight, just to see whether they feel different." — Dr. Aubrey de Grey Our Guest   Dr. Aubrey de Grey is a biomedical gerontologist and founder of the LEV Foundation, focused on repairing aging-related cellular damage. Based in Silicon Valley, he earned his BA in computer science and Ph.D. in biology from the University of Cambridge. His research targets the characterization and repair of aging damage. A Fellow of the Gerontological Society of America and the American Aging Association, he advises numerous journals and organizations and is a sought-after speaker at scientific and public events. Resources and Links Peak Human Labs https://www.youtube.com/@peakhumanlabs/videos https://www.peakhuman.ca/ https://www.instagram.com/peakhumanlabs/?hl=en https://open.spotify.com/show/5hx9R37ElxgzCrBccRWoHd?si=8atK0n82QbeL3DWg5-vjvg&nd=1&dlsi=ce0f77aa4f304724   Dr. Sanjeev Goel https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca   Dr Aubrey de Grey https://www.levf.org/ https://www.linkedin.com/in/aubrey-de-grey-24260b/ https://web.facebook.com/aubrey.degrey/?_rdc=1&_rdr

“Dr. Admasu earned his PhD in Biochemistry from national university of Singapore. In his PhD work he investigated interactions between lifespan extending drugs with the aim of engineering synergistic benefits in C. elegans. Dr. Admasu is currently a research fellow at SENS Research Foundation. His research focus on isolation and characterization of secondary senescent cells using surface markers and identification of novel approaches to ablate multiple types of senescent cells. He recently identified a novel senolytic approach to kill multiple types of senescent cells.Source: https://www.sens.org/endingagingforum-2022/ About the showThe Learning With Lowell show is a series for the everyday mammal. In this show we'll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn't normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. Learning with lowell linksYoutube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips:https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com/ Tesfahun Admasu linkshttps://www.linkedin.com/in/tessadmasuhttps://scholar.google.com.sg/citations?user=nJA2aaUAAAAJ&hl=enhttps://twitter.com/TessAdmasu Timestamps00:00 Introducing Tesfahun Admasu00:30 Ethiopia Conflict explained18:00 Abiy Ahmed in power21:30 Resolving conflict in Ethiopia23:15 Working for a better Ethiopia27:40 Future of Ethiopia / Abiy Ahmed31:50 Hope for the future of Ethiopia35:40 How can people help Ethiopia39:40 Tesfahun Admasu PhD Singapore / Aging & lifespan Extension47:55 Aging and the Immune system / SENS foundation01:02:08 Non-SENS senolytics trials that you're excited about (FANQ)01:07:05 Book recommendations01:08:33 End comment AgingResearch #EthiopiaConflict #longevity

Prof. Alexandra Stolzing is a pioneer in biogerontological engineering at Loughborough University. With over two decades of experience, including work at SENS Research Foundation, Prof. Stolzing shares insights on:Targeting senescent cells for anti-aging therapiesRevolutionizing cryopreservation techniquesDeveloping breath-based aging biomarkersHarnessing AI for rapid drug discovery in aging researchLearn how her journey from Germany to the UK shaped her multidisciplinary approach to solving aging. Discover the challenges and opportunities in longevity research, including the critical need for basic science funding.Show notes here: https://peterottsjo.beehiiv.com/ Hosted on Acast. See acast.com/privacy for more information.

Our topic in this episode is progress with ending aging. Our guest is the person who literally wrote the book on that subject, namely the book, “Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime”. He is Aubrey de Grey, who describes himself in his Twitter biography as “spearheading the global crusade to defeat aging”.In pursuit of that objective, Aubrey co-founded the Methuselah Foundation in 2003, the SENS Research Foundation in 2009, and the LEV Foundation, that is the Longevity Escape Velocity Foundation, in 2022, where he serves as President and Chief Science Officer.Full disclosure: David also has a role on the executive management team of LEV Foundation, but for this recording he was wearing his hat as co-host of the London Futurists Podcast.The conversation opens with this question: "When people are asked about ending aging, they often say the idea sounds nice, but they see no evidence for any actual progress toward ending aging in humans. They say that they've heard talk about that subject for years, or even decades, but wonder when all that talk is going to result in people actually living significantly longer. How do you respond?"Selected follow-ups:Aubrey de Grey on X (Twitter)The book Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our LifetimeThe Longevity Escape Velocity (LEV) FoundationThe SENS paradigm for ending aging , contrasted with the "Hallmarks of Aging" - a 2023 article in Rejuvenation ResearchProgress reports from the current RMR projectThe plan for RMR 2The RAID (Rodent Aging Interventions Database) analysis that guided the design of RMR 1 and 2Longevity Summit Dublin (LSD): 13-16 June 2024Unblocking the Brain's Drains to Fight Alzheimer's - Doug Ethell of Leucadia Therapeutics at LSD 2023 (explains the possible role of the cribriform plate)Targeting Telomeres to Clear Cancer – Vlad Vitoc of MAIA Biotechnology at LSD 2023How to Run a Lifespan Study of 1,000 Mice - Danique Wortel of Ichor Life Sciences at LSD 2023XPrize HealthspanThe Dublin Longevity Declaration ("DLD")Music: Spike Protein, by Koi Discovery, available under CC0 1.0 Public Domain Declaration

Reason is co-founder and CEO of Repair Biotechnologies. He has been an active angel investor in the longevity industry since its earliest days, with investments including Oisin Biotechnologies and Leucadia Therapeutics. He is a long-standing and well-connected patient advocate for aging research, involved in numerous fundraising and outreach initiatives conducted by organizations such as the Methuselah Foundation and SENS Research Foundation since the early 2000s. He is also the founder and writer of Fight Aging!, a noted news and commentary website in the biotechnology community. Prior to his involvement in the biotechnology industry, Reason was a consultant in the software industry. He holds Masters degrees in Astrophysics from the University of St. Andrews and Space Physics from Rice University.

Dialogues In Longevity - A discussion with Dr. Aubrey de Grey & Dr. Michael Rose about the past, present and future of longevity biotechnology Host - Ira S. Pastor Special thanks to longevity advocate Eric Schulke (https://ruliaderic.wordpress.com/) for helping to organize and coordinate the episode - Dr. Aubrey de Grey, Ph.D., is President & Chief Science Officer of the Longevity Escape Velocity (LEV) Foundation ( https://www.levf.org/ ), an organization focused on proactively identifying and addressing the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease. Dr. de Grey is internationally recognized as a visionary biomedical gerontologist who devised the Strategies for Engineered Negligible Senescence: a comprehensive set of methods to rejuvenate the human body, thereby preventing age-related ill health and mortality. He has co-founded multiple non-profit organizations – including Methuselah Foundation, SENS Research Foundation, and now LEV Foundation – to specifically enable and accelerate its development and clinical translation. Dr. de Grey received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. He is the author of 'The Mitochondrial Free Radical Theory of Aging', 'Ending Aging', and a large number of academic papers. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the advisory boards of numerous scientific journals and research organizations. He is a prolific speaker who regularly presents at conferences and events world-wide. Dr. Michael Rose, Ph.D. ( https://www.faculty.uci.edu/profile/?facultyId=5261 ) is the Director of the Network for Experimental Research on Evolution (NERE), and Professor in the Department of Ecology and Evolutionary Biology at the University of California, Irvine, where his main area of work over the years has been the evolution of aging. He received his PhD from the University of Sussex in 1978. In 1991, Dr. Rose published seminal work per his text 'Evolutionary Biology of Aging' exploring a view of the subject based on antagonistic pleiotropy, the hypothesis that aging is caused by genes that have two effects, one acting early in life and the other much later. The genes are favored by natural selection as a result of their early-life benefits, and the costs that accrue much later appear as incidental side-effects that we identify as aging. Dr. Rose's laboratory has conducted the longest-running artificial selection experiment designed to test the theory of antagonistic pleiotropy using Fruit flies (Drosophila melanogaster) bred for longevity by collecting eggs from the longest-lived flies in each generation. The experiment has run since 1981, and has produced flies with quadruple the original life span. In 1997, Dr. Rose was awarded the Busse Research Prize by the World Congress of Gerontology. He has authored 10 books, including 'The Long Tomorrow: How Advances in Evolutionary Biology Can Help Us Postpone Aging'. Support the show

The second part of my conversation with George Chanos. He discusses the incredible advances in healthcare and the potential for humans to live longer than ever before. He shares insights from Aubrey de Grey of the SENS Research Foundation, who believes that the first person to live to a thousand years old is alive today. While the specific numbers and timelines are up for debate, George emphasizes that the important thing is that these advancements are coming in our lifetime and will have significant global implications. Get ready for a future of ever-shifting global relations and technological warfare.[00:00:26] Advances in healthcare.[00:05:11] Reversing aging and genetic code change.[00:07:32] Surviving the technological tsunami.[00:11:21] Implications of spatial web.[00:16:07] TikTok as a news source.[00:19:36] Future wars and warfare.[00:25:33] Ukraine's NATO membership debate.[00:28:00] Insect drones in urban areas.[00:31:27] Unlearning and relearning.

Dr. Amit Sharma was awarded a Master's degree in Biomedical Sciences from Delhi University, India. He received his PhD in 2009 in Biotechnology from University of Pune for his work demonstrating microRNA regulation of cytokines invovled in allergic inflammation in mice models. Dr. Sharma's postdoctoral research at the Buck Institute, Novato, California involved investigating novel molecular regulatory pathways in regards to genotoxic stress and cellular senescence in invertebrate and mammalian models. Dr. Sharma has recently joined SENS Research Foundation as Group Lead in the Senescence Immunology Research Group. His research focus involves studying how aging and senescence affects the immune system and his research group will also investigate strategies to harness the immune system in mitigating deleterious effects of senescent cells with translational focus. Newsletter sign up (new and exciting developments)https://learningwithlowell.us12.list-manage.com/subscribe?u=08ed8a56013d8b3a3c01e27fc&id=6ecaa9189b Join this channel to get access to perks: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q/join https://youtu.be/8QwvcRvsT_0 Over 321 books from 170 plus interviews over 5 yearshttps://www.learningwithlowell.com/over-321-books-from-170-interviews-over-5-years-for-autodidacts/ PODCAST INFO:The Learning With Lowell show is a series for the everyday mammal. In this show we'll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn't normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com/ Amit Sharma Linkshttps://www.sens.org/about-us/team/https://youtu.be/AoRb1Z0XanMhttps://www.sens.org/our-research/https://www.linkedin.com/in/amit-sharma-1613b189/ Timestamps00:00 Dr. Amit Sharma00:45 Which path to achieve longevity/ healthspan02:40 integrated approach03:50 Typical week working on longevity07:20 Black swan events / SENS foundation08:30 Too high risk ideas09:09 Innovation brain / Elon Musk10:50 Dyslexia thinking in 3d and how Amit thinks12:40 Seeing opportunities14:20 Amit Sharma Leadership style16:00 Spinning off companies vs staying in pure research18:30 Mentorship, life events, inspiration and seeing longevity as the path for her21:00 Skills to be successful in longevity24:55 Project / moments at SENS that is awesome27:15 Longevity and Iron30:17 Visualizing senescence apoptosis32:30 Other uses / Cancer applications / USF34:40 Immune system not aware of eyes35:52 Blood brain barrier degradation with ate, NK cells, t cells36:47 T -cells, inflammation, and alzheimer's38:44 Crazy ideas for treating alzheimer's disease40:40 Cost to build an Amit Sharma center of research within SENS / Idea for Lisa43:00 Donating money to SENS / mito mouse45:00 Ancient infections hiding in genome47:35 Gut microbiome longevity Drosophila52:25 Mice / research / history of work56:30 Cell culture, senescence, mouse models creating new perspectives57:40 FanQ How do you know that the allogeneic CAR-NK cells won't cause Graft vs Host disease?1:00:01 FANQ How many possible senescent cell markers do you think there may be in senescent cells? Do you see being able to target say 70% of Senescent cells with just say 10 markers?1:03:50 FANQ How far do you think you are from an IND application?1:05:55 FANQ Do you have an orphan indication you might want to target first?1:06:50 Book recommendations1:10:00 Amit on never retiring1:10:30 What he needs help with

Dr. Aubrey de Grey, Ph.D., is President & Chief Science Officer of the Longevity Escape Velocity (LEV) Foundation ( https://www.levf.org/ ), an organization focused on proactively identifying and addressing the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease. Dr. de Grey is internationally recognized as a visionary biomedical gerontologist who devised the Strategies for Engineered Negligible Senescence: a comprehensive set of methods to rejuvenate the human body, thereby preventing age-related ill health and mortality. He has co-founded multiple non-profit organizations – including Methuselah Foundation, SENS Research Foundation, and now LEV Foundation – to specifically enable and accelerate its development and clinical translation. Dr. de Grey received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. He is the author of The Mitochondrial Free Radical Theory of Aging (1999), Ending Aging (2007), and a large number of academic papers. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the advisory boards of numerous scientific journals and research organizations. He is a prolific speaker who regularly presents at conferences and events world-wide. Support the show

Reason is co-founder and CEO of Repair Biotechnologies. He has been an active angel investor in the longevity industry since its earliest days, with investments including Oisin Biotechnologies and Leucadia Therapeutics. He is a long-standing and well-connected patient advocate for aging research, involved in numerous fundraising and outreach initiatives conducted by organizations such as the Methuselah Foundation and SENS Research Foundation since the early 2000s. He is also the founder and writer of Fight Aging!, a noted news and commentary website in the biotechnology community.Cholesterol is presented as much an enemy as a friend in this look at how direct clearance of localized excess cholesterol outperforms other strategies in a number of important medical conditions.Session summary: Reason, Fight Aging | Towards Biotechnology to Finally Defeat Cholesterol - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight's virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts. Hosted on Acast. See acast.com/privacy for more information.

  Dr. Aubrey De Grey, a distinguished biomedical gerontologist, is a visionary in the field of aging research. His groundbreaking work has focused on finding ways to slow, prevent, and even reverse the aging process in humans and animals. As the founder of the SENS Research Foundation, Dr. De Grey has played a pivotal role in advancing the field of gerontology and biogerontology.  With his unique background and revolutionary approach to aging, Dr. Aubrey De Grey has upended conventional wisdom, sparking both intrigue and controversy as he seeks to extend healthy human life. But what will be the implications of his discoveries? Dr. De Grey's passion for exploring the possibilities of ageless living has led him to challenge conventional wisdom and inspire countless gerontologists to rethink their approach to aging. Look into the Strategies for Engineered Negligible Senescence (SENS) Foundation, founded by Dr. Aubrey De Grey, to learn more about their research and approach to combating aging and age-related diseases. Explore the concept of Longevity Escape Velocity, which Dr. De Grey has proposed as a way to stay one step ahead of the aging process through repeated application of damage repair therapies. Familiarize yourself with the history of science and the paradigm shifts that have occurred throughout time, as this can help provide context for understanding the resistance Dr. De Grey faced in proposing his ideas on aging. Research the different types of age-related damage and their potential impact on health, including Alzheimer's disease, cancer, arthritis, and sarcopenia, to understand the importance of focusing on health span rather than just life span. Consider the analogy between living organisms and manmade machines, as proposed by Dr. De Grey, to better understand the concept of damage accumulation and the potential for repair in both living and non-living systems. Investigate the concept of negligible senescence as coined by Caleb Finch and how this idea has influenced Dr. De Grey's approach to engineered negligible senescence. Look for opportunities to engage with the gerontology community and participate in discussions surrounding the potential for extending health spans and combating age-related diseases. Engineered Negligible Senescence Engineered Negligible Senescence (ENS) seeks to prevent or reverse the aging process, focusing on the repair of cellular and molecular damage that accrues over time. The underlying principle is that our biological age, determined by the wear and tear our bodies undergo, can be slowed down and potentially extended through vigilant maintenance. The ultimate goal of ENS is not simply to prolong life for its own sake, but to increase health span, curtailing age-related illnesses such as Alzheimer's, cancer, sarcopenia, and arthritis. Dr. Aubrey De Grey, a guest on the Beauty and the BS with Dr. Peter Grossman podcast, elaborated on the concept of ENS and its importance in addressing age-related health problems. Although his ideas faced resistance initially, De Grey remains confident in their potential benefits within his lifetime. By focusing on periodic, preventative maintenance, he believes it may be possible to delay the issues related to aging by 20 or 30 years, ultimately leading to longer, healthier lives. About the Host, Dr. Peter Grossman: https://grossmanmed.com/about Podcast Page: www.beautyandthebspodcast.com

With his unique background and revolutionary approach to aging, Dr. Aubrey De Grey has upended conventional wisdom, sparking both intrigue and controversy as he seeks to extend healthy human life. But what will be the implications of his discoveries? In this episode of Beauty and the BS with Dr. Peter Grossman, you will be able to:  1. Discover the significance of gerontology and biogerontology in addressing the aging process.  2. Understand engineered negligible senescence and its role in comprehensive periodic maintenance.  3. Explore how repairing molecular and cellular damage can counteract aging.  4. Learn about the potential of stem cell therapy as a cutting-edge damage repair strategy.  5. Delve into the controversy surrounding prolonged human life and the benefits it may hold. Dr. Aubrey De Grey, a distinguished biomedical gerontologist, is a visionary in the field of aging research. His groundbreaking work has focused on finding ways to slow, prevent, and even reverse the aging process in humans and animals. As the founder of the SENS Research Foundation, Dr. De Grey has played a pivotal role in advancing the field of gerontology and biogerontology.  With a keen understanding of the complex interplay between molecular and cellular damage, he has developed innovative strategies for promoting healthier, longer lives. Dr. De Grey's passion for exploring the possibilities of ageless living has led him to challenge conventional wisdom and inspire countless gerontologists to rethink their approach to aging. The key moments in this episode are: 00:00:08 - Introduction to Gerontology and Biomedical Gerontology 00:02:13 - Chronological Age versus Biological Age 00:05:03 - Aging and Damage Accumulation 00:11:20 - Engineered Negligible Senescence 00:16:50 - Postponing Aging to Battle Health Issues 00:17:58 - Life Expectancy vs. Lifespan 00:21:17 - Longevity and the Controversy 00:24:02 - Categorizing Aging Damage 00:25:12 - Cell Loss and Stem Cell Therapy 00:27:05 - The Importance of Classification The resources mentioned in this episode are: Look into the Strategies for Engineered Negligible Senescence (SENS) Foundation, founded by Dr. Aubrey De Grey, to learn more about their research and approach to combating aging and age-related diseases. Explore the concept of Longevity Escape Velocity, which Dr. De Grey has proposed as a way to stay one step ahead of the aging process through repeated application of damage repair therapies. Familiarize yourself with the history of science and the paradigm shifts that have occurred throughout time, as this can help provide context for understanding the resistance Dr. De Grey faced in proposing his ideas on aging. Research the different types of age-related damage and their potential impact on health, including Alzheimer's disease, cancer, arthritis, and sarcopenia, to understand the importance of focusing on health span rather than just life span. Consider the analogy between living organisms and manmade machines, as proposed by Dr. De Grey, to better understand the concept of damage accumulation and the potential for repair in both living and non-living systems. Investigate the concept of negligible senescence as coined by Caleb Finch and how this idea has influenced Dr. De Grey's approach to engineered negligible senescence. Look for opportunities to engage with the gerontology community and participate in discussions surrounding the potential for extending health spans and combating age-related diseases. Engineered Negligible Senescence Engineered Negligible Senescence (ENS) seeks to prevent or reverse the aging process, focusing on the repair of cellular and molecular damage that accrues over time. The underlying principle is that our biological age, determined by the wear and tear our bodies undergo, can be slowed down and potentially extended through vigilant maintenance. The ultimate goal of ENS is not simply to prolong life for its own sake, but to increase health span, curtailing age-related illnesses such as Alzheimer's, cancer, sarcopenia, and arthritis. Dr. Aubrey De Grey, a guest on the Beauty and the BS with Dr. Peter Grossman podcast, elaborated on the concept of ENS and its importance in addressing age-related health problems. Although his ideas faced resistance initially, De Grey remains confident in their potential benefits within his lifetime. By focusing on periodic, preventative maintenance, he believes it may be possible to delay the issues related to aging by 20 or 30 years, ultimately leading to longer, healthier lives. About the Host, Dr. Peter Grossman: https://grossmanmed.com/about Podcast Page: www.beautyandthebspodcast.com

Aubrey David Nicholas Jasper de Grey is an English author and biomedical gerontologist. He is the author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007). He is known for his view that medical technology may enable human beings alive today not to die from age-related causes. As an amateur mathematician, he has contributed to the study of the Hadwiger–Nelson problem in geometric graph theory, making the first progress on the problem in over 60 years. De Grey is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies. He has been interviewed in recent years in a number of news sources, including CBS 60 Minutes, the BBC, The Guardian, Fortune Magazine, The Washington Post, TED, Popular Science, Playboy, The Colbert Report, Time, the Skeptics' Guide to the Universe, and The Joe Rogan Experience. He was the Chief Science Officer of the SENS Research Foundation. In late 2022, de Grey formed LEV Foundation as President and Chief Science Officer.This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/3240049/advertisement

Instead of a traditional newsletter, we'll do the Joel message and video launch This episode of the Rejuvenation Roundup Podcast features our Rejuvenation Roundup, as well as Ryan O'Shea's episode of Lifespan News on rapamycin's impact on embryo formation and a Life Noggin video on SENS Research Foundation's OncoSENS program! You can also subscribe on your favorite podcasting platform. Learn more at lifespan.io/roundup 0:00 Intro 0:40 Polyphenols and Mediterranean Diet Help with Weight Loss (1) 3:20 Activated Natural Killer Cells Fight Senescence in Humans (2) 5:23 NMN May Improve NAD+ and Walking Speed (3) 9:11 Cancer May Have Finally Met Its Match with OncoSENS (4) 13:00 Rapamycin Reduces DNA Damage & Improves Maturation of Egg Cells (5) Links: 1 - https://www.lifespan.io/news/polyphenols-help-reduce-visceral-fat/ 2 - https://www.lifespan.io/news/activated-natural-killer-cells-fight-senescence-in-humans/ 3 - https://www.lifespan.io/news/study-suggests-nmn-may-improve-nad-and-walking-speed/ 4 - https://youtu.be/r0cnavajNac 5 - https://youtu.be/dfX-lxzXmSA

This episode of the Rejuvenation Roundup Podcast features our Rejuvenation Roundup, as well as Ryan O'Shea's episode of Lifespan News on whether or not coffee is associated with longevity and a Life Noggin video on SENS Research Foundation's MitoSENS program! You can also subscribe on your favorite podcasting platform. Learn more at lifespan.io/roundup 0:00 Intro 0:37 The Effects of Niacin on Alzheimer's in Mice (1) 1:44 Nicotinamide Riboside May Make Existing Cancer Worse (2) 3:58 Protecting Memory Through Gut Bacteria (3) 6:05 Can Drinking Coffee Help You Live Longer? (4) 9:41 Your Body Needs This Tiny Change To Live Longer (5) Links: 1 - https://www.lifespan.io/news/the-effects-of-niacin-on-alzheimers-in-mice/ 2 - https://www.lifespan.io/news/nicotinamide-riboside-may-make-existing-cancer-worse/ 3 - https://www.lifespan.io/news/protecting-memory-through-gut-bacteria/ 4 - https://youtu.be/A3-MenLH-Vk 5 - https://youtu.be/goZ_HPBcT_Q

One area of technology that is frequently in the news these days is rejuvenation biotechnology, namely the possibility of undoing key aspects of biological aging via a suite of medical interventions. What these interventions target isn't individual diseases, such as cancer, stroke, or heart disease, but rather the common aggravating factors that lie behind the increasing prevalence of these diseases as we become older.Our guest in this episode is someone who has been at the forefront for over 20 years of a series of breakthrough initiatives in this field of rejuvenation biotechnology. He is Dr Aubrey de Grey, co-founder of the Methuselah Foundation, the SENS Research Foundation, and, most recently, the LEV Foundation - where 'LEV' stands for Longevity Escape Velocity.Topics discussed include:*) Different concepts of aging and damage repair;*) Why the outlook for damage repair is significantly more tangible today than it was ten years ago;*) The role of foundations in supporting projects which cannot receive funding from commercial ventures;*) Questions of pace of development: cautious versus bold;*) Changing timescales for the likely attainment of robust mouse rejuvenation ('RMR') and longevity escape velocity ('LEV');*) The "Less Death" initiative;*) "Anticipating anticipation" - preparing for likely sweeping changes in public attitude once understanding spreads about the forthcoming available of powerful rejuvenation treatments;*) Various advocacy initiatives that Aubrey is supporting;*) Ways in which listeners can help to accelerate the attainment of LEV.Music: Spike Protein, by Koi Discovery, available under CC0 1.0 Public Domain DeclarationSome follow-up reading:https://levf.orghttps://lessdeath.org

In the fifth episode of the Longevity & Aging Series, Dr. Amit Sharma, Group Lead from SENS Research Foundation, Mountain View, CA, discusses a research paper he co-authored that was published in Volume 14, Issue 5, of Aging (Aging-US), entitled, “Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells.” DOI - https://doi.org/10.18632/aging.203931 Corresponding Author - Amit Sharma - amit.sharma@sens.org Video - https://www.youtube.com/watch?v=WQR8_gm2gUI Abstract In the context of aging and age-associated diseases, Natural Killer (NK) cells have been revealed as a key cell type responsible for the immune clearance of senescent cells. Subsequently, NK cell-based therapies have emerged as promising alternatives to drug-based therapeutic interventions for the prevention and treatment of age-related disease and debility. Given the promise of NK cell-mediated immunotherapies as a safe and effective treatment strategy, we outline an improved method by which primary NK cells can be efficiently enriched from human peripheral blood across multiple donors (ages 20-42 years old), with a practical protocol that reliably enhances both CD56dim and CD56bright NK cells by 15-fold and 3-fold, respectively. Importantly, we show that our co-culture protocol can be used as an easily adaptable tool to assess highly efficient and selective killing of senescent cells by primary NK cells enriched via our method using longer co-culture durations and a low target to effector ratio, which may be more physiological than has been achieved in previous literature. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.203931 Longevity & Aging Series Aging (Aging-US) and FOXO Technologies have teamed up for a special collaboration on aging research with a monthly video series: Longevity & Aging Series. This series invites Aging researchers to speak with host Dr. Brian Chen, an adjunct faculty member at the University of California San Diego and Chief Science Officer of FOXO Technologies. Learn more - https://www.aging-us.com/longevity Keywords - aging, senescence, natural killer cells, NKCC, immune surveillance About Aging-US Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at https://www.Aging-US.com​​ and connect with us: SoundCloud - https://soundcloud.com/Aging-Us Facebook - https://www.facebook.com/AgingUS/ Twitter - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/agingus​ LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM

Explore the latest updates in longevity research in the September 2022 edition of the Rejuvenation Roundup Podcast! This episode of the Rejuvenation Roundup Podcast features our Rejuvenation Roundup, a look at a Life Noggin and SENS Research Foundation video exploring senescent cells (AKA "zombie cells"), Ryan O'Shea's episode of Lifespan News focused on JellyfishDAO, and more! You can also subscribe on your favorite podcasting platform. Learn more at lifespan.io/roundup 0:00 Intro 0:39 Umbilical Plasma Injections Reduce Biological Age in Humans (1) 2:13 Brief Rapamycin Treatment in Early Adulthood Combats Aging (2) 4:27 Ketogenic and Mediterranean Diets vs. Diabetes (3) 7:42 The Zombie Problem Inside of You (4, Life Noggin) 11:09 JellyfishDAO (5, Lifespan News) 16:12 Longevity Summit Dublin Links: 1 - https://www.lifespan.io/news/umbilical-plasma-injections-reduce-biological-age-in-humans/ 2 - https://www.lifespan.io/news/brief-rapamycin-treatment-in-early-adulthood-combats-aging/ 3 - https://www.lifespan.io/news/ketogenic-and-mediterranean-diets-effective-against-diabetes/ 4 - https://youtu.be/X2ixGNRdmpk 5 - https://youtu.be/83dcEIKM3Do 

➡ Nous enregistrons nos podcasts avec Riverside: Cliquer sur le lien pour commencer une période d'essai : https://tinyurl.com/5bxnwnda ⚠️ Découvrez du contenu EXCLUSIF (pas sur la chaîne) ⚠️ ⇒ https://the-flares.com/y/bonus/ ⬇️⬇️⬇️ Infos complémentaires : sources, références, liens... ⬇️⬇️⬇️ Sommaire : 0:00:00 Introduction 0:02:40 Pourquoi souhaitez vaincre le vieillissement et vivre plus longtemps ? 0:04:43 Quelles sont les plus grandes difficultés pour traiter la vieillesse ? 0:08:33 La théorie de réparation des dégâts (damage repair) 0:10:51 Le vieillissement est-il une maladie ou non ? 0:13:05 Quels ont été les progrès effectués dans la recherche ? 0:17:15 Comment convaincre les institutions publiques ? 0:20:13 L'état de la médecine anti-vieillesse en Chine ? 0:21:39 Voit-on une croissance exponentielle dans la recherche contre le vieillissement ? 0:23:00 Que faudrait-il changer pour accélérer la recherche ? 0:25:37 Quelles sont les grandes étapes que nous avons déjà franchies et celles restantes ? 0:28:46 Comment dépasser la limite maximale de durée de vie ? 0:34:31 L'utilité des médicaments et suppléments pour vivre en bonne santé plus longtemps 0:36:00 Le rôle des sénolytiques et thérapie liées au sang ? 0:40:28 Pourquoi les souris testées ne sont pas maintenues en vie ? 0:43:00 Les promesses de la médecine régénérative 0:47:00 Les raisons qui ont poussé Aubrey de Grey a travailler sur le vieillissement 0:49:00 L'affaire "me too" contre Aubrey de Grey 0:51:42 Comment évolua la société si le vieillissement est sous contrôle médical ? 0:53:32 Quel serait le moyen le plus efficace pour accélérer la recherche ? 0:54:54 Les autres centres d'intérêts transhumanistes 0:57:34 Comment contribuer sur le plan personnel ? ----------------------------------------------------------------- ✍️ QUI EST DERRIÈRE CE CONTENU ? ☕ ➡ Production : The Flares - https://the-flares.com ➡ Realisation : Gaëtan Selle - https://www.the-flares.com/y/gaetan-selle/ ➡ Animateurs : Gaëtan Selle - https://www.the-flares.com/y/gaetan-selle/ ➡ Animateurs : Didier Coeurnelle - https://the-flares.com/y/didier-coeurnelle/ -----------------------------------------------------------------

Dr. Kevin Perrott, Ph.D. is Founder and CEO, OpenCures (https://opencures.org/), Adjunct Professor, University of Alberta, Co-Founder and Advisor, Oisin Biotechnologies, President, of Global Healthspan Policy Institute, and Co-Founder and Treasurer, SENS Research Foundation. Kevin is a successful entrepreneur and owner of the largest motorcycle and snowmobile dealership in Canada, Riverside Honda and Skidoo Sales in Edmonton, Alberta. He became a cancer survivor, an experience which clearly highlighted the deficiencies of the current health technology development paradigm where the customer has almost no input in the development of their own health solutions. Armed with the realization that nothing is more valuable than health and the time to enjoy it with those you love, Kevin resolved to put his energies towards addressing these deficiencies. In 2003, Kevin joined Aubrey de Grey and David Gobel to form the Methuselah Foundation which offered competitive prizes for advances in longevity science. A few years later he became a co-founder with Aubrey de Grey and others of SENS Research Foundation to develop interventions able to repair or make harmless the damage that accumulates and underlies multiple age-related disorders. Mostly recently, Kevin formed OpenCures as a for-benefit corporation helping individuals perform self-directed research, generate data, and focus the value of data on the health solutions they are interested in. Kevin has authored and co-authored several peer-reviewed articles all focused on accelerating the science underlying the development of therapies for degenerative diseases. He is a co-founder of multiple non-profit and for-profit entities whose missions are aligned with that purpose. Kevin has a PhD in Biomedical Engineering from University of Alberta, with work performed at the Campisi Lab of the Buck Institute studying the effects of natural compounds on senescence, as well as a BSc, Double Major, in Biology and Chemistry.

#agereversal #lifeextension #humanlongevity #sensfoundation 2021 was a pivotal year in life extension research, we are much closer to finding the elixir which could stop, slow & possibly even revere human aging, Sens Research Foundation has been pioneering in Anti Aging. Dr. Amit Sharma was awarded a Master's degree in Biomedical Sciences from Delhi University, India. He received his Ph.D. in 2009 in Biotechnology from the University of Pune for his work demonstrating microRNA regulation of cytokines involved in allergic inflammation in mice models. Dr. Sharma's postdoctoral research at the Buck Institute, Novato, California involved investigating novel molecular regulatory pathways in regards to genotoxic stress and cellular senescence in invertebrate and mammalian models. Dr. Sharma has recently joined SENS Research Foundation as Group Lead in the Senescence Immunology Research Group. His research focus involves studying how aging and senescence effects the immune system and his research group will also investigate strategies to harness the immune system in mitigating deleterious effects of senescent cells with a translational focus. https://www.linkedin.com/in/amit-sharma-1613b189 https://www.sens.org Kindly Subscribe to CHANGE- I M POSSIBLE youtube channel www.youtube.com/ctipodcast

Most people think about Parkinson's disease as being just what it's called: a disease — a distinct clinical entity, which can be treated as a thing to itself. In fact, however, like all the other diseases of aging, it's the result of the lifelong accumulation of specific kinds of cellular and molecular damage that happen to all of us as part of the biological aging process. PD results from specific kinds of aging damage accumulating in key parts of the brain and nervous system, but similar damage accumulates in other aging tissues, causing dysfunction in those local tissues; these degenerative processes get labeled "diseases" when they reach a tipping point and the tissue can no longer carry out its normal function. The good news is that we now have a strategy for preventing, delaying, and one day even reversing Parkinson's and other diseases of aging through the revolution in rejuvenation biotechnology: therapies that directly remove, repair, replace, or render harmless the damage of aging. By clearing out that damage from the tissues, functionality can be restored and youthful health and vigor with it. SENS Research Foundation https://www.sens.org is a 501(c)3 medical research charity that is working hard to accelerate the development of a comprehensive suite of rejuvenation biotechnologies, to bring the benefits as soon as possible to as many people as possible. My guest today is Michael Rae, Science Writer at SENS Research Foundation, and coauthor with cofounder Dr. de Grey of "Ending Aging:" http://www.amazon.com/dp/0312367074 http://smile.amazon.com/dp/B01EBAP43C/  

Dr. Aubrey de Grey is a biomedical gerontologist and author based in Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) biomedical research charity that performs and funds laboratory research dedicated to combating the aging process. In addition, he is Editor-in-Chief of Rejuvenation Research, the world's highest-impact peer-reviewed journal focused on intervention in aging. He received his BA in computer science and Ph.D. in biology from the University of Cambridge. His research interests encompass the characterisation of all the types of self-inflicted cellular and molecular damage that constitute mammalian aging and the design of interventions to repair and/or obviate that damage. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organisations.

A panel talk with scientists and thought leaders in age reversal and longevity science. Featuring: Aubrey de Grey (Founder of SENS Research Foundation, author of "Ending Aging")  David Sinclair (Harvard Medical School, Life Biosciences, author of "Lifespan: Why We Age -- and Why We Don't Have to") Joao Pedro de Magalhaes (University of Liverpool, CSO at Centaura) Liz Parrish (Founder of Bioviva Science) Jean Hebert (Albert Einstein College of Medicine, author of "Replacing Aging") Alexandra Stolzing (SENS Research Foundation, Loughborough University) Greg Fahy (Intervene Immune) David Gobel (Methuselah Foundation, Methuselah Fund) Hosted by: Laura Minquini (MYKIGAI, Let's Talk Longevity), Avi Roy (Oxford University), and Nathan Cheng (Longevity Marketcap / Longevity List)  

Aubrey de Gray, the godfather of the longevity movement, has catered his research on how to put the breaks on ageing. Passionate about slowing the ageing process, the biomedical gerontologist and chief science officer co-founded the SENS Research Foundation to help fund research on living a longer life.Today, de Gray shares ways we can slow ageing. We discuss the definition of ageing, why we're living longer now than those who lived in the 19th century, and how nutrition plays a part in longevity.We talk about:What made de Gray want to study ageingThe definition of ageing and why we ageThe lifelong process and late-life processWays to extend our livesThe history of age longevity and medicineNutrition and age longevity

Aubrey de Grey is the Chief Science Officer and Co-Founder of SENS Research Foundation, an organization dedicated to changing the way the world researches and treats age-related diseases by researching, developing, and promoting the means to defeat the human aging process. A biomedical gerontologist, he co-authored Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime to explain the science behind the biomedical technology that would slow, and even reverse, aging. He is one of the foremost speakers on the topic of aging as a curable disease.

Check out our sponsors: Better Help: Get 10% off your first month at https://betterhelp.com/impacttheory Taft: Visit taftclothing.com and use code IT10 for 10% off your order of any full priced boot, shoe, or sneaker purchase. Helium 10: Get 50% OFF your first month of Helium 10 Platinum at Helium10.com and use code IMPACT at check out. SHEATH: Go to sheathunderwear.com/impact for 20% off your order with promo code: IMPACT Scientific break-throughs are happening all around you. As technology advances, biologists such as the Chief Science Officer of the SENS Research Foundation, Aubrey de Grey, is leading the way to pioneering tech that will allow you to choose how long you want to live. For years scientists have been trying to find a way to slow down the aging process, but Aubrey introduces the idea of repairing the damage that aging does on the body to theoretically restore the body’s biological age to maybe 30 years younger. If you are familiar with the obsession I’ve had with living forever, you already know how much this excites me.   SHOW NOTES: Quality of Life | Aubrey on why a long life depends on the quality and being invested in choice [0:58] Reverse Aging | Why damage repair could be easier than slowing aging & the push back met [4:40] Indefinite Life | Aubrey on why the result of expected life for reversed aging could be indefinite [8:08] Structure Repair | Landing on the idea of repairing structure to restore cellular level function [9:32] Pushback | Aubrey on pushback among scientists about reverse aging in biology [11:17] Body Damage | Aubrey on self-inflicted damage being reversed to same level 30 years prior [14:13] Longevity Escape Velocity | Aubrey on his theory how to reverse biological age 30 years [16:26] Types of Damage | 7 categories of damage that correspond to therapeutic methods of repair [21:18] Stem Cell Therapy | Aubrey explains how stem cells could treat loss of cell problems [22:17] Cancer Treatments | Aubrey gives category of damage due to too many cells [23:26] Senescent Cells | Aubrey explains how these cells can promote cancer [26:53] Mitochondrial Mutations | Aubrey explains problems at the molecular level inside cells [28:53] Cellular Waste | Aubrey breaks down how cellular waste over years impacts old age [33:35] Macular Degeneration | Aubrey explains specific enzymes that could prevent blindness  [35:24] Excretion | Aubrey explains diseases that could be resolved by breaking down waste [37:50] Alzheimer’s | Breaking down amyloid as extracellular waste and modest benefit [39:22] Advancing Therapies | Aubrey gives sobering guess how close effective therapies are [44:07]     QUOTES: “I want to make sure that my choice about how long to live, and, of course, how high quality that life will be, is not progressively taken away from me by aging.” [2:24]   “Old age is something that evolution doesn't care about at all. Evolution only cares about the propagation of genetic information.” [34:41]   “you've got to fix them all. You haven't got to fix any of them perfectly. But you've got to fix them all pretty well.” [43:28]   “what excites me is typically the breakthroughs that would take me half an hour background to describe why it's even important.” [46:16]   Guest Bio: Dr. de Grey is the biomedical gerontologist who devised the SENS platform and established SENS Research Foundation to implement it. He received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. Dr. de Grey is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association   Follow Aubrey De Grey: Website: https://www.sens.org/ Twitter: https://twitter.com/aubreydegrey LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/   Dive Deeper On Related Episodes: Reset Your Age with David Sinclair https://youtu.be/IEz1P4i1P7s Lifestyle For Longevity with Kellyann Petrucci https://youtu.be/l9QO0JlnU8w Secrets To Longevity https://youtu.be/Ulm01gzU8rU    

Better Help: Get 10% off your first month at https://betterhelp.com/impacttheory Taft: Visit taftclothing.com and use code IT10 for 10% off your order of any full priced boot, shoe, or sneaker purchase. Helium 10: Get 50% OFF your first month of Helium 10 Platinum at Helium10.com and use code IMPACT at check out. SHEATH: Go to sheathunderwear.com/impact for 20% off your order with promo code: IMPACT Scientific break-throughs are happening all around you. As technology advances, biologists such as the Chief Science Officer of the SENS Research Foundation, Aubrey de Grey, is leading the way to pioneering tech that will allow you to choose how long you want to live. For years scientists have been trying to find a way to slow down the aging process, but Aubrey introduces the idea of repairing the damage that aging does on the body to theoretically restore the body’s biological age to maybe 30 years younger. If you are familiar with the obsession I’ve had with living forever, you already know how much this excites me.   SHOW NOTES: Quality of Life | Aubrey on why a long life depends on the quality and being invested in choice [0:58] Reverse Aging | Why damage repair could be easier than slowing aging & the push back met [4:40] Indefinite Life | Aubrey on why the result of expected life for reversed aging could be indefinite [8:08] Structure Repair | Landing on the idea of repairing structure to restore cellular level function [9:32] Pushback | Aubrey on pushback among scientists about reverse aging in biology [11:17] Body Damage | Aubrey on self-inflicted damage being reversed to same level 30 years prior [14:13] Longevity Escape Velocity | Aubrey on his theory how to reverse biological age 30 years [16:26] Types of Damage | 7 categories of damage that correspond to therapeutic methods of repair [21:18] Stem Cell Therapy | Aubrey explains how stem cells could treat loss of cell problems [22:17] Cancer Treatments | Aubrey gives category of damage due to too many cells [23:26] Senescent Cells | Aubrey explains how these cells can promote cancer [26:53] Mitochondrial Mutations | Aubrey explains problems at the molecular level inside cells [28:53] Cellular Waste | Aubrey breaks down how cellular waste over years impacts old age [33:35] Macular Degeneration | Aubrey explains specific enzymes that could prevent blindness  [35:24] Excretion | Aubrey explains diseases that could be resolved by breaking down waste [37:50] Alzheimer’s | Breaking down amyloid as extracellular waste and modest benefit [39:22] Advancing Therapies | Aubrey gives sobering guess how close effective therapies are [44:07]     QUOTES: “I want to make sure that my choice about how long to live, and, of course, how high quality that life will be, is not progressively taken away from me by aging.” [2:24]   “Old age is something that evolution doesn't care about at all. Evolution only cares about the propagation of genetic information.” [34:41]   “you've got to fix them all. You haven't got to fix any of them perfectly. But you've got to fix them all pretty well.” [43:28]   “what excites me is typically the breakthroughs that would take me half an hour background to describe why it's even important.” [46:16]   Guest Bio: Dr. de Grey is the biomedical gerontologist who devised the SENS platform and established SENS Research Foundation to implement it. He received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. Dr. de Grey is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association   Follow Aubrey De Grey: Website: https://www.sens.org/ Twitter: https://twitter.com/aubreydegrey LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/   Dive Deeper On Related Episodes: Reset Your Age with David Sinclair https://youtu.be/IEz1P4i1P7s Lifestyle For Longevity with Kellyann Petrucci https://youtu.be/l9QO0JlnU8w Secrets To Longevity https://youtu.be/Ulm01gzU8rU  

BONUS EPISODES & EARLY RELEASES: https://www.patreon.com/auxoro Aubrey de Grey is a research scientist, author, and Chief Science Officer of the SENS Research Foundation.  Aubrey de Grey Links:Ending AgingSENS Research FoundationDonate to SENSSubscribe to SENS Newsletter Auxoro Links:InstagramFacebookTwitterTikTokYouTubeNewsletterPatreon (Bonus Episodes + Early Releases) 

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about why SENS was founder and why the research that the foundation undertakes is not done by other organizations. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey will talk about the hallmarks of aging that he defined and more specifically about the stiffening of the extra cellular matrix a hallmark that was in his original list but not the 2013 paper. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

In this episode of the Judgment Call Podcast – Aubrey de Grey and I talk about: 00:02:16 How Aubrey de Grey got into the ‘longevity research‘ in the first place?00:07:01 How Aubrey got the confidence to put a precise year to the ‘end of aging’.00:12:01 What were the biggest obstacles to overcome in persuading the public that ‘aging can be ended’00:13:30 Was setting up a money price for the extension of the lifespan of mice a good idea?00:21:10 Why the longevity industry is burgeoning at the seams suddenly?00:25:09 Will the benefit of an extended lifespan be equally available to a large part of the population?00:31:01 Once aging is solved will we see a population of 100 billion on earth?00:34:50 How Aubrey envisions life ‘past the Singularity’?00:38:30 How will our brains react to aging? Are there any drugs that we can use right now that may delay aging?00:42:01 Is the the FDA to blame for the slow innovation in the healthcare industry? Has COVID changed the regulatory environment? You may watch this episode on Youtube – The Judgment Call Podcast Episode #58 – Aubrey de Grey (Can we finally reverse aging ‘forever’?!). Aubrey de Grey is the Chief Science Officer of the SENS Research Foundation. He has been an evangelist of longevity research for decades. He is also the author of ‘Ending Aging‘. Big Thanks to our Sponsors! ExpressVPN – Claim back your Internet privacy for less than $10 a month! Mighty Travels Premium – incredible airfare and hotel deals – so everyone can afford to fly Business Class and book 5 Star Hotels! Sign up for free! Divvy – get business credit without a personal guarantee and 21st century spend management plus earn 7x rewards on restaurants & more. Get started for free! Brex – get a business account, a credit card, spend management & convertible rewards for every dollar you spend. Plus now earn $250 just for signing up (Terms & Conditions apply).

Dr. Aubrey de Grey is a biomedical gerontologist based in Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) biomedical research charity that performs and funds laboratory research dedicated to combating the aging process. In addition, he is Editor-in-Chief of Rejuvenation Research, the world's highest-impact peer-reviewed journal focused on intervention in aging. He received his BA in computer science and Ph.D. in biology from the University of Cambridge. His research interests encompass the characterization of all the types of self-inflicted cellular and molecular damage that constitute mammalian aging and the design of interventions to repair and/or obviate that damage. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits (uncompensated) on the editorial and scientific advisory boards of numerous journals and organizations. He is a highly sought-after speaker who gives 40-50 invited talks per year at scientific conferences, universities, companies in areas ranging from pharmaceutical to life insurance, and to the public. Support the show (http://www.paypal.me/BangProductions )

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about his view on the latest rejuvenation technology. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about his view of what the future of aging will look like Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about how the idea of an extended lifespan is being accepted by society and some of the implications of this. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Since the beginning of civilization, humans have been fueled by a desire to avoid the decay that's coming with old age. Today, we spend billions of dollars each year to eradicate cancer, dementia or diabetes. But even when we find cures for these and other diseases, we still don't change our ultimate prognosis: death. But what if, instead of focusing on diseases, we would focus on eradicating aging and reverse engineering our biological clock? Today, science is on the brink of providing us with the proverbial Fountain of Youth and the possibility of living radically extended and healthy lifespans. For those who are familiar with the subjects of aging, transhumanism and futurology, today's guest, Dr. Aubrey de Grey needs no introduction. He is the biomedical gerontologist known for his view that medical technology will one day allow humans to control the aging process and live healthily into our hundreds, or maybe even thousands. In fact, Aubrey has said that the first human being to live to 500 years old may already be alive today. Dr. Aubrey de Grey is the Chief Science Officer of SENS Research Foundation, a California based biomedical research charity that performs and funds laboratory research dedicated to combating aging. In addition, Aubrey is editor-in-chief of Rejuvenation Research, the world's highest impact peer-reviewed journal focused on intervention in aging. In this conversation with Aubrey, you'll hear:02:36 Why aging is the biggest health crisis the world is facing 04:28 The reason why we think about aging differently than other diseases 07:11 What causes aging 08:46 The hallmarks of aging and the strategies to prevent them 15:07 Does it make sense to maintain ourselves as well as possible until the anti aging technologies arrive via diet, biohacking and self care? 18:22 Why it is vital politicians and policy makers deal with the topic of drastically extended lifespan now. 24:08 How society and our economic systems will benefit from a healthy older generation with a drastically extended lifespan 25:53 Why overpopulation is not the problem it is commonly thought to be with regards to drastically extended lifespans 33:48 How far we are from the point in time when people will live to 150 years and more 41:32 Aubrey's practices Resources mentioned in this episode: https://www.sens.org (SENS Research Foundation) https://amzn.to/3vmjUZR (Lifespan: Why We Age and Why We don't Have to) by David Sinclair

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey will talk about his view on the epigenetic aging clocks and their value in aging research. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey will talk about the hallmarks of aging that he defined and more specifically about the stiffening of the extra cellular matrix a hallmark that was in his original list but not the 2013 paper. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

Aubrey de Grey is a biomedical gerontologist. He’s the co-founder and chief science officer of the SENS Research Foundation, which is a non-profit that does basic research on aging and treatments for aging. We start with the basics of aging, and some critical reactions to the notion that ageing could ever be overcome. Then Aubrey tells us about the seven types of damage that cause ageing and their corresponding repair technologies. I also ask him about the limits of model organisms in aging research. If at some point you’d like to skip to Aubrey talking about time estimates for ending aging and the effective altruism case for ending aging - you can skip approximately 1 hour and 32 minutes into the podcast.

Dr. Aubrey de Grey is a biomedical gerontologist based in Cambridge, UK and Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) charity dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world's highest-impact peer-reviewed journal focused on intervention in aging. EPISODE LINKS: SENS Research Foundation Website: https://www.sens.org/​ Aubrey de Grey's Twitter: https://twitter.com/aubreydegrey​ Ian Bott's Twitter: https://twitter.com/IanBott​ OUTLINE: 0:00​ - Introduction 1:43​ - How to define "aging" 3:25​ - The importance of ending aging 4:05​ - Why a "pro-aging trance" exists 5:59​ - Why repair is better than prevention 8:49​ - The central causes of aging 10:44​ - The impact of CRISPR 13:11​ - Rapid vs. Incremental Progress 14:36​ - "Eureka" Moments 15:56​ - Motivation to work on rejuvenation 17:51​ - Background as an AI researcher 18:38​ - When to "break the rules" 20:41​ - Problems with how research is funded 24:43​ - The "triangular logjam" 28:08​ - How to support human longevity research 29:07​ - How human values might change CONNECT: Subscribe to this YouTube channel United Sigma Intelligence Association (USIA): https://usiassociation.org​ USIA Twitter:

Dr. Aubrey de Grey is a biomedical gerontologist based in Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) biomedical research charity that performs and funds laboratory research dedicated to combating aging. In addition, he is Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging.He received his BA in computer science and Ph.D. in biology from the University of Cambridge. His research interests encompass the characterization of all the types of self-inflicted cellular and molecular damage that constitute mammalian aging and the design of interventions to repair and/or obviate that damage.Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations. He is a highly sought-after speaker who gives 40-50 invited talks per year at scientific conferences, universities, companies in areas ranging from pharma to life insurance, and to the public.Topics Discussed:Brief overview of SENSWhy try to end aging?How soon do you think we will end aging?What role does rejuvenation biotech play in the COVID-19 pandemic? How would regenerative medicine help us better cope with the pandemic?How are you implementing the techniques you research in your own life?Which breakthrough are you most proud of?Aubrey's Links:LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/Personal Website: https://www.sens.org/Company Website: https://www.mfoundation.org/Twitter: https://twitter.com/aubreydegrey

Aubrey Grey of the SENS Research Foundation and AgeX Therapeutics, Inc tells Tom about the treatments he is developing to reverse the effects of ageing, which he believes could extend human life expectancy tenfold. Aubrey reveals what this could cost, how this could affect what we are able to eat and drink, and how soon he thinks this could be made available to the general public.

In this important conversation on health, David Gornoski sits down with Jim O'Neill, CEO of the SENS Research Foundation. How do we effectively fight viruses such as COVID-19? O'Neill brings attention to the urgency of strengthening our immune systems. Why should we look into anti-aging? Anti-aging research, O'Neill says, looks into the possibility of targeting senescent cells where many diseases take hold. How soon can we see the results of this research? Given our societal norms, is overcoming death through scientific means something that we should look into? Visit A Neighbor's Choice website at aneighborschoice.com

Join me as I speak with Aubrey de Grey, Chief Science Officer and Co-founder of the SENS Research Foundation. Dr. de Grey is the biomedical gerontologist who devised the SENS platform and established SENS Research Foundation to implement it. There are plenty of subject matter experts; there are far fewer subject matter creators. I think this distinction needs to be made in the case of Aubrey de Grey, for he is writing new chapters in the book of human experience. In this episode, he is going to break down for us the breakdown of the human body.

Aubrey de Grey, Chief Science Officer at SENS Research Foundation, explores the concept of using biomedical technology and regenerative medicine to postpone aging-derived debilitation and death. We dive into many questions surrounding this topic, including the benefits of reversing aging/age-related disease vs. slowing it down and the potential ethical or medical concerns around extending life beyond what is “natural.”Schedule a meeting with Natalie Yeadon: https://www.meetwithnatalie.comNatalie Yeadon LinkedIn: https://www.linkedin.com/in/natalieyeadon/Impetus Digital Website: https://www.impetusdigital.com/Impetus Digital LinkedIn: https://www.linkedin.com/company/impetus-digital/Impetus Digital Twitter: https://twitter.com/ImpetusadboardsImpetus YouTube: https://www.youtube.com/ImpetushealthcareAubrey de Grey: https://www.linkedin.com/in/aubrey-de-grey-24260b/SENS Research Foundation: https://www.sens.org/

Our conversation covers the importance of non-academic institutions in science, strategies for combating for repair the damage of aging, and an exploration of how extending human lifespan will change the Earth. In Dr. de Gray's perspective, age-related decline is a medical problem like any other that can be treated and cured by cutting edge technology. He's devoted himself to this pursuit as a founder of the SENS Research Foundation, the Methuselah Foundation, and the medical startup AgeX. Please subscribe to our channel so we can bring you more like this!!! Support Dr. de Grey & DS when you buy his books: Ending Aging: https://amzn.to/31Wyo4V Advocate for An Indefinite Human Lifespan: https://amzn.to/3kPHJUP SENS Foundation: https://www.sens.org Aubrey de Grey: https://twitter.com/aubreydegrey More readings from us: https://demystifyingscience.com Demystifying Science Mailing List: http://eepurl.com/gRUCZL Let's talk! @DemystifySci Twitter: https://twitter.com/demystifysci Instagram: https://www.instagram.com/demystifysci Facebook: https://www.facebook.com/demystifysci ~~~~~~~~~~~~~~ Music: ~~~~~~~~~~~~~~ Shilo Delay: https://soundcloud.com/laterisgone Blippy Trance by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/5759-blippy-trance License: http://creativecommons.org/licenses/by/4.0/ --- Support this podcast: https://anchor.fm/demystifying-science/support

Future Hacker hosted the biomedical gerontologist Dr. Aubrey de Grey, the Chief Science Officer and Co-Founder of the SENS Research Foundation. We had an enlightening discussion about the global crusade to defeat aging, which he spearheads, and how to take an engineering approach to prevent the aging process and the diseases related to it. Will we be able to avoid aging-related illnesses from happening? Are we ready to go deeper into the gene-editing path? What are the consequences? Check out our interview and follow @aubreydegrey

Future Hacker hosted the biomedical gerontologist Dr. Aubrey de Grey, the Chief Science Officer and Co-Founder of the SENS Research Foundation. We had an enlightening discussion about the global crusade to defeat aging, which he spearheads, and how to take an engineering approach to prevent the aging process and the diseases related to it. Will we be able to avoid aging-related illnesses from happening? Are we ready to go deeper into the gene-editing path? What are the consequences? Check out our interview and follow @aubreydegrey

Aubrey De Grey is one of the most recognized gerontologist (the study of aging), Chief Science Officer at SENS Research Foundation, and VP of New Technology at AgeX Therapeutics. His TED talk: A roadmap to end aging has been viewed more than 4.3M times, where he provocatively claims that the first human being to live to 1,000 is already born today. In our convo, we dig into actionable steps you can do to reduce your aging process, the latest research on what science has discovered about longevity, cryogenic freezing your brain and organs (and how transformative this is to living longer), and more. Learn more about Aubrey here: https://www.sens.org/ Subscribe to the podcast here: https://podcasts.apple.com/us/podcast/growth-minds/id1482999379

Aubrey is the Chief Science Officer and Co-founder of the SENS Research Foundation and author of the book Ending Aging. He is working on undoing the damage of aging in order to help humans live much longer and healthier lives than most have ever imagined could be possible. -- Thank you for listening to Pod of Jake! All shares and reviews are appreciated! If you enjoy this podcast, you might like reading blogofjake.com If you prefer listening over reading, you might prefer Blog of Jake's blog on tape, available through any of your favorite podcast providers. Website: podofjake.com Twitter: @blogofjake Email: jake@blogofjake.com Call: superpeer.com/jake Support: patreon.com/blogofjake Bitcoin: 3ESGQxrJZmGqd2SifqCUiHPvah1uWtN1Zd

Explore the latest updates in longevity research in the April 2020 edition of the Rejuvenation Roundup Podcast, hosted by Ryan O'Shea of Future Grind! This episode features an interview with Dr. Aubrey de Grey of the SENS Research Foundation. More at lifespan.io/roundup

Scientists who study the biology of Aging agreed that we would someday be able to slow down the aging process substantially.Dr. Aubrey de Grey, Chief Science Officer at SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, believes that the critical biomedical technology required to eliminate aging derived debilitation and death is now within reach.In his book “Ending Aging” he and his research assistant Michael Rae described the details of this biotechnology. They explained that the aging of the human body, just like the Aging of manmade machines, results from an accumulation of various types of damage. As with manmade machines, this damage can periodically be repaired, leading to the indefinite extension of the machines fully functional lifetime just as is routinely done with classic cars.We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage.By demystifying aging, Dr. Aubrey de Grey systematically dismantles the fatalist presumption that aging will forever defeat the efforts of medical science.He is the author of “Ending Aging,” rejuvenation breakthroughs that could reverse human Aging in our lifetime. His book is available at Amazon.com: https://www.amazon.com/Ending-Aging-Rejuvenation-Breakthroughs-Lifetime/dp/B01EBAP43C/ref=sr_1_1?keywords=Ending+Aging+aubrey+de+grey&qid=1583555592&sr=8-1Aubrey's Links:LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/Personal Website: https://www.sens.org/Company Website: https://www.mfoundation.org/Twitter: https://twitter.com/aubreydegreyThis podcast is also available on Podcast.BoomerLiving.tv at the link: https://podcast.boomerliving.tv/ending-aging-by-reversing-human-aging-in-our-lifetime-with-dr-aubrey-de-grey-phd/

Aubrey De Grey is the founder of the SENS Research Foundation, an organization developing medical interventions to repair the damage the body does to itself over time. Stated more directly, Aubrey de Grey and his organization aim to defeat aging. In 2016 I interviewed him for the book "Advancing Conversations: Aubrey de Grey." here is the second part of the audio recording of that interview. It’s Sunday, March 1st, 2020 and I’m Douglas Lain the publisher of Zero Books and the host of this podcast. If you enjoy our podcasts support us on Patreon. Our Patreon supporters usually get access to two podcasts a week, audio versions of our youtube videos, as well as occasional Pop the Left specials. Zero Books book club members get access to Zero Books titles each month as well as a chance to join in a discussion with Zero Books authors.

Aubrey de Grey is an English author and theoretician in the field of gerontology and the Chief Science Officer of the SENS Research Foundation.

Aubrey de Grey is an English author and theoretician in the field of gerontology and the Chief Science Officer of the SENS Research Foundation.

Aubrey De Grey is the founder of the SENS Research Foundation, an organization developing medical interventions to repair the damage the body does to itself over time. Stated more directly, Aubrey de Grey and his organization aim to defeat aging. In 2016 Douglas Lain interviewed him for the book "Advancing Conversations: Aubrey de Grey." The first part of the audio recording of that interview is available now for our Patreon supporters.

SPEAKERS Aubrey de Grey Chief Science Officer, SENS Research Foundation; Vice President of New Technology Discovery, AgeX Therapeutics Inc. Robert Hariri M.D., Ph.D., Founder, Chairman, and CEO, Celularity Inc. Cynthia Kenyon Vice President of Aging Research, Calico; Professor Emeritus of Biochemistry and Biophysics, UC San Francisco Chip Walter Author, Immortality, Inc: Renegade Science, Silicon Valley Billions, and the Quest to Live Forever Alison van Diggelen Host, "Fresh Dialogues"; BBC Contributor—Moderator This program was recorded in front of a live audience at the Oshman Family JCC in Palo Alto, CA on January 30th, 2020. ** This Podcast Contains Explicit Language **

Meet Aubrey De Grey – Chief Science Officer at SENS Research Foundation, VP of New Technology Discovery at AgeX Therapeutics, and editor-in-chief of Rejuvenation Research, the highest-impact peer-reviewed academic journal focused on postponing aging. He works on the development of medical innovations that can postpone all forms of age-related ill-health with an undivided focus is on rejuvenation: that is, the active repair of the various types of molecular and cellular damage which eventually cause age-related disease and disability, as opposed to the mere retardation of the accumulation of such damage. Our guest tells his story of how he came to be a biologist from being destined to be a pianist according to his mother in the beginning and later choosing programming out of a wish to make more of a contribution to the progress of mankind. Insights Switching fields and how it helped Aubrey find fulfilment in his work. Understanding the process of aging – how it happens and what is the rational, sustainable, and effective way to combat it. Why public awareness on the topic is important, and how Aubrey has been striving to raise awareness. What makes us age faster is not just the unhealthy habits of ours, but also the mechanisms like breathing that are essential to our life. Whether fasting helps you combat the aging process or not. A revolutionary view in gerontology and how it became mainstream, thanks to Aubrey's untiring efforts. Where we hope to be in the coming decades in terms of defeating the process of aging altogether or even partially. Why individual contributions are important in the field of gerontology. Aubrey and his foundations Connect on LinkedIn - https://www.linkedin.com/in/aubrey-de-grey-24260b/ - SENS Research Foundation - https://www.sens.org/ The Methuselah Foundation - https://www.mfoundation.org/ ABOUT THE HOST My name is Sam Harris. I am a British entrepreneur, investor and explorer. From hitchhiking across Kazakstan to programming AI doctors I am always pushing myself in the spirit of curiosity and Growth. My background is in Biology and Psychology with a passion for improving the world and human behaviour. I have built and sold companies from an early age and love coming up with unique ways to make life more enjoyable and meaningful. Sam: Instagram (https://www.instagram.com/samjamsnaps/) Quora (https://www.quora.com/profile/Sam-Harris-58) Twitter (https://twitter.com/samharristweets) LinkedIn (https://www.linkedin.com/in/sharris48/) Sam's blog - SamWebsterHarris.com (https://samwebsterharris.com/) Support the Show - Patreon (https://www.patreon.com/growthmindset) Sponsor - Feals (https://feals.com/growth) Feals has me feeling my best every day and it can help you too.  Become a member today by going to Feals dot com slash growth and you'll get 50% off your first order with free shipping.  That’s F-E-A-L-S dot com slash growth to become a member and get 50% automatically taken off your first order with free shipping.  Feals dot com slash growth. Summary Aubrey's Career Path "I wanted to be a scientist, but ultimately, I wanted to make a difference to the world. And I recognized that scientists, in the long run, make the most difference.” Having chosen programming at the age of 15 and for the purpose of making more of a difference to the world, Aubrey continued in that career till he got exposed to something much more demanding. "I started programming, and I thought that one of the biggest problems the world faces is that people have to spend so much of their time doing stuff that they wouldn’t do unless they were being paid for it – I’ll stop that by helping in artificial intelligence research to create more automation. ” Learn why Aubrey chose to switch fields back in 1990 and pursue a career that could ultimately fulfil his desire of being able to make as big of a difference to the world as possible. "Having found out that nobody was working on trying to keep people healthy late in life – not properly, anyway – I thought, what? I better switch fields, really? And that’s what led to my moving into the biology of aging back in the early 1990s. ” https://images.unsplash.com/photo-1566669437687-7040a6926753?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=667&q=80 Raising Awareness and Concern about the Process of Aging Our guest is the person who played a key role in the introduction and spreading of this revolutionary idea in the field of gerontology – a switch from making efforts for the prevention of ‘aging’ to making efforts for the remediation of the process called ‘aging.’ "I was fortunate enough to have a few ideas in the late 90s that were quite well received, so I rose to great prominence in gerontology very quickly. In the year 2000, I had the idea that comprehensive damage repair is the most promising and practical way to keep people healthy late in life. ” "My goal is and has always been to grow this movement to a point that I become unnecessary, that there are people in the field who are better than me. And then I will retreat into glorious obscurity. ” https://images.unsplash.com/photo-1519171920866-a020bf47357b?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=750&q=80 A New Concept in Gerontology It took him much and more to make people realize that not only do they want to live, but they also want to live long and live healthy – that eventually leads to the idea that they want to defeat the biologically deteriorative process called aging. "If it’s all about simple health care and if one recognizes that longevity is simply a side effect of not getting sick, then the argument becomes a great deal easier to make. ” Learn why defeating aging is more about reducing the combined effect of time on biological systems than trying to prevent that effect from occurring at all. "The most common sense and most practical approach to keeping people healthy late in life was simply to repair the damage that the body does to itself throughout life, not necessarily perfectly, but well enough so that the overall amount of damage that remains in the body is within the capacity of the body to tolerate. ” https://images.unsplash.com/photo-1505682614136-0a12f9f7beea?ixlib=rb-1.2.1&auto=format&fit=crop&w=751&q=80 Striving for the Cause Aubrey has contributed much and more to the spreading of awareness about all these concepts because that is how the scientists can motivate people from all domains to donate and contribute to the progress of research that eventually benefits the whole of mankind. "If you’re working on something that is interesting and important, it’s not such a problem to get people to come and work for you.” https://images.unsplash.com/photo-1522211988038-6fcbb8c12c7e?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=750&q=80 Having an Understanding in Multiple Fields Learn how switching fields is one of the most innovative and productive things that can happen in one’s career. It opened a whole new dimension for Aubrey, and it also allows for a profitable transfer of skill sets from one domain to another. "It’s quite clear that when people switch fields, they very often do really good things in the new field because they’ve got the skill set to work on really hard problems because of their transferable skill, but they’re not encumbered by the conventional wisdom that everybody else in the field have.” https://images.unsplash.com/photo-1546188994-07c34f6e5e1b?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=751&q=80 Hope for the Future Aubrey has high hopes for the future of gerontology and welcomes any feedback or help that people have to offer him on his way to the achievement of these universal goals. "I think within the next 10 years, we will have reached the threshold of research that I historically have called robust master rejuvenation. It’s only a matter of time before we can bring aging under comprehensive medical control.” He also believes that only a collective effort can uproot the problem altogether. "I believe that at the end of the day, this problem of aging will not be solved by one person or one organization. It will be a collective effort because it should divide and conquer approach.” https://images.unsplash.com/photo-1478796415026-3c85ee65975e?ixlib=rb-1.2.1&ixid=eyJhcHBfaWQiOjEyMDd9&auto=format&fit=crop&w=750&q=80 Moving Forward Aubrey is trying to get people to move past all the obstacles that are stopping them from being concerned about aging. Any contribution to the movement that he has initiated is much appreciated. "It’s all about past people’s fear of getting their hopes up and knowing that people have been wrong about the defeat of aging right through the history of civilization.” Subscribe! If you enjoyed the podcast please subscribe and rate it. And of course, share with your friends! Special Guest: Aubrey De Grey.

This episode will take you through Dr. Aubrey de Grey’s Seven Pillars of aging, the research that he's currently doing, his opinion on biological age, AGEs and the different sources, and the impact of growth hormone on biological age.Who is Dr. Aubrey de Grey?Aubrey de Grey is an English author and biomedical gerontologist. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, Inc.He is the editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging and co-author of Ending Aging. He is known for his view that medical technology may enable human beings alive today not to die from age-related causes.He is also an amateur mathematician who has contributed to the study of the Hadwiger–Nelson problem.His research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage. De Grey is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies.He has been interviewed in recent years in a number of news sources, including CBS 60 Minutes, the BBC, The New York Times, Fortune Magazine, The Washington Post, TED, Popular Science, The Colbert Report, Time, the Skeptics' Guide to the Universe, and The Joe Rogan Experience. He is also a member of Flooved advisory board.Highlights[1:57] Where are we in the battle against aging?[4:29] Dr. de Grey explains the seven aspects of aging[8:38] Effects of lifestyle on the AGEs and aging[12:23] Measures for biological age[18:07] Why haven’t we evolved past aging?[20:28] Alzheimers, cancer and cardiovascular disease as components of aging[24:44] Transitioning from computer science to gerontology[27:53] Dr. de Grey answers the Superhuman sixResourcesThe Health Optimisation SummitHorvath’s Epigenetic clockReversing Biological Age by Greg FahyEnding Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our LifetimeOur sponsor today is CAR.O.L You don’t have time for that 45 minute jog.You need something fast, efficient, and leaves you wanting more. My favorite tool for this is the CAR.O.L. She is a life-changing bike, that provides you all the endurance you need into two 20 second bursts. Yes, you read that right. That’s 40 seconds of max-effort, including the warm up and cool downs, you get a kick-ass workout in 8 minutes and 40 seconds. The CAR.O.L is a resistance bike powered by artificial intelligence, which personalizes and optimizes the resistance, so you hit your maximum intensity levels and maximize glycogen depletion every single time. The proof is really in the pudding. CAR.O.L’s effectiveness was independently verified by the American Council on Exercise. I gave the CAR.O.L bike spin at Health Optimization Summit in London this year, and she kicked my ass so much that I had to get one. Check out CAR.O.L at carolfitai.com If you have limited time and want an amazing workout, which basically everyone that listens to this show does, use the code DECODING150 for a big discount, head over to CarolfitAI.com to secure yours.Continue Your High Performance Journey with Dr. de GreyWebsiteTwitterDisclaimer This information is being provided to you for educational and informational purposes only. This is being provided as a self-help tool to help you understand your genetics, biodata and other information to enhance your performance. It is not medical or psychological advice. Virtuosity LLC, or Decoding Superhuman, is not a doctor. Virtuosity LLC is not treating, preventing, healing, or diagnosing disease. This information is to be used at your own risk based on your own judgment. For the full Disclaimer, please go to (Decodingsuperhuman.com/disclaimer). See acast.com/privacy for privacy and opt-out information.

In this installment of the Future Grind podcast host Ryan O'Shea speaks with Dr. Josiah Zayner, the former NASA scientist who in 2017 became the first known human to attempt to modify themselves using CRISPR gene editing technology. Josiah's controversial company, The ODIN, provides educational courses and sells DIY gene editing kits for everything from bacteria to frogs, and soon plans to offer kits for the DIY modification of human cells. They discuss his experiments in human augmentation, bodily autonomy, the healthcare industry, and so much more. In addition to his work with The ODIN, Josiah hosts the annual Biohack The Planet conference, which will be held in Las Vegas from August 31st to September 1st, 2019. Speakers include Dr. Aubrey de Grey of the SENS Research Foundation, Hamilton Morris of the VICE series Hamilton's Pharmacopeia, magician and biohacker Anastasia Synn, and many more! More info and tickets at http://biohacktheplanet.com/   Show Notes: https://futuregrind.org Subscribe on iTunes: https://itunes.apple.com/us/podcast/future-grind-podcast-science-technology-business-politics/id1020231514 Support: https://futuregrind.org/support Follow along - Twitter - https://twitter.com/Ryan0Shea  Instagram - https://www.instagram.com/ryan_0shea/  Facebook - https://www.facebook.com/RyanOSheaOfficial/  If you have any questions or are interested in supporting or sponsoring Future Grind, you can reach us at hello@futuregrind.org.

Aubrey de Grey, Ph.D., Chief Science Officer and Co-founder of SENS Research Foundation, delivers an overview of aging and the many health problems that develop in our advanced years. Dr. de Grey is a respected member of the science community; he is the noted biomedical gerontologist who devised the innovative SENS platform and co-founded the SENS Research Foundation to further it. Dr. de Grey has written about his work and as an established researcher, he has been appointed to the editorial and scientific advisory boards of many journals, organizations, etc. Dr. de Grey is a Fellow of the Gerontological Society of America as well as the American Aging Association. He holds a BA in Computer Science and a Ph.D. in Biology from the prestigious University of Cambridge.  Dr. de Grey discusses his research in aging and the motivations for tackling the career. As he states, aging is the number one medical problem as it causes more suffering. He was motivated to research in this area because he found that not enough was being done to focus on aging and the myriad of problems that come with it. He talks about the many excuses that are given as reasons to simply accept aging as it is, or not focus on it at all, such as “it's inevitable…everything ages,” or the philosophical—“death gives meaning to life,” or social—“maybe we could do this, but it would create new problems worse than the problem we are solving.” And as the Ph.D. states, none of these excuses stand up to even the faintest scrutiny, however, they still remain quite popular.  Dr. de Grey explains that ‘why' and ‘how' we age are fairly well understood, but it is the understanding of what we already know that is important, to take the information we know to be true and utilize that to design and implement therapies that will prevent the health problems of old age. And this is the core of what Dr. de Grey's foundation, SENS Research, seeks to accomplish. SENS Research Foundation works to create, promote, and provide wide-ranging access to all kinds of therapies that can cure and prevent the diseases and detrimental disabilities of aging by essentially repairing the damage that builds up within our bodies over long periods of time. SENS Research seeks to change the way the world researches and thus cares for age-related ill health. The Ph.D. discusses stem cell therapy and its ability to repair the damage, loss of cells, etc. As he explains, stem cells can be injected that target areas within the body and repair damage, replace lost cells, and thus keep the body area, organ, etc. functioning in a healthier state. He explains in detail how cells function and the processes used to make genetic modifications. Additionally, Dr. de Grey expounds upon the kinds of complex research they engage in at his foundation, and the types of conditions that they seek to bring more understanding to in order to combat them.

Dr Aubrey De Grey is one of the world's leading experts in solving the problem of human ageing. A biomedical gerontologist, as well as Chief Science Officer and co-founder of the SENS Research Foundation (https://sens.org/), Dr DeGrey is at the forefront of research in solving diseases and disabilities related to human ageing, that will likely lead to us living much longer and healthier lives in the very near future. A few years ago, Dr De Grey put forward that the first person to live to be 1,000 years old has already likely been born, and if you're under 40 years of age now and in reasonably good health, you have a good chance of staying young and healthy forever. And while that may sound like science fiction to some, and was controversial in some fields, the fact is that as Dr De Grey will explain in this episode, we don't need to solve ageing tomorrow for this to happen — we only need to extend life by a decade or so with new advances in technology, and keep succeeding in that respect to make this a reality. In this episode, we discuss what it may take for humanity to live to be 1,000 years old, the kinds of problems we need to solve to achieve this, some of the breakthroughs SENS has been responsible for so far, why we may be only a few years away from some serious breakthroughs in solving the problem of ageing, why extending life won't only be something for the super-rich, some of the consequences of having a population living to be much longer, the things you can do now to extend your life — which may surprise you — and so much more. I urge all of you to check out the phenomenal work SENS is doing, which you can learn more about via the links below.   SENS: https://sens.org/ SENS ON INSTAGRAM: @senseresearchfoundation SENS RESEARCH: https://www.sens.org/our-research/    CONNECT Connect with Leon The Alchemist online for more intensive biohacking, longevity, and performance advice daily, with exclusive content you won't find anywhere else: INSTAGRAM: @LeonTheAlchemist | https://www.instagram.com/leonthealchemist  TWITTER: @AlchemistLeon | https://twitter.com/alchemistleon LINKTREE: https://linktr.ee/leonthealchemist WEBSITE: http://bioalchemy.co COURSE: http://bio.ax/    LEARN Want to take your biohacking skills to the next level? Wake up feeling better each and every day? Or as Dr Aubrey De Grey has suggested, see if you can implement some of the longevity biohacks that may see you living to 1,000 years or more with advancements in technology? Then my intensive biohacking course The Alchemist's Guide to Biohacking (http://bio.ax/) is something you should consider becoming a student of. Use the code "HALF" during the first month of this podcast being launched to get 50% off lifetime access, with all future updates. Check out this biohacking course at: http://bio.ax/    SUPPORT I spend a ton of time putting together this podcast, and would love your support. Whether as simple as reviewing this podcast, to checking out the products I recommend, or even becoming a student of my intensive biohacking course "The Alchemist's Guide To Biohacking", I appreciate every human who supports me, however large or small the action. ITUNES: https://apple.co/2GQnXH2  SUB ON GOOGLE: https://bit.ly/2SbvJ05  BIOHACKING COURSE: http://bio.ax/

Our guest today needs no introduction. It is the one and only Aubrey de Grey, a leading biomedical gerontologist, computer scientist, author, and entrepreneur whose work in longevity research is widely known and regularly referenced by many in the industry. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, Inc. In many respects, Aubrey is one of the most prominent, if not provocative figures in longevity science. What makes Aubrey so provocative? Well, aside from his exceptionally long beard, he is the leading advocate of the controversial view that technology may one day enable humans to control the aging process and live well into our hundreds, or even thousands. As much as he believes this, he also knows that there are two main obstacles to achieving this utopia: money and time. While Aubrey’s research is funded by some of the biggest investors, he notes that the “pro-aging trance” has historically held them back. This conversation with Aubrey uncovers the theory of his pro-aging trance phenomena and many incredibly insightful details, including: How to remove senescent cells from our body What investments are at the top of his list Why investor Peter Thiel gave him $6M in funding What locations are hot spots for longevity research and innovation Where he’s seen the biggest breakthroughs When we can expect to benefit from his research What is the “pro-aging trance” and why it’s holding us back This was a really exciting episode that gave the team a chance to hear a unique perspective. We hope you enjoy the episode and share it with your friends, family, and colleagues. About Aubrey Aubrey de Grey Aubrey de Grey on Twitter Show Links Sens.org Senolytics Unity Biotechnology Peter Thiel Insilico medicine Aubrey de Grey – Living to 1000 Years Old Ending Aging by Aubrey de Grey

The October 2018 edition of the Rejuvenation Roundup Podcast is now available! This podcast from Future Grind and Lifespan.io / Life Extension Advocacy Foundation brings you the latest breakthroughs in life extension and anti-aging science. This episode features Mike Kope of the SENS Research Foundation, Michael Greve of the Forever Healthy Foundation, Didier Cournelle of the Healthy Life Extension Society, Charlie Kam, and more! Links at lifespan.io/roundup. Subscribe on iTunes!

Today we explore human longevity and life extension efforts focused on adding healthy years to a person's lifespan, and even reversing the aging process.   My guest is Dr. Aubrey de Grey, a leading voice in the field and the Chief Science Officer of the SENS Research Foundation which is doing pioneering work on significantly extending healthy, active lifespans. Aubrey is a biomedical gerontologist with a degree in Computer Science and a Ph.D. in Biology. He is author of the book "Ending Aging" and Editor-in-Chief of the scientific journal "Rejuvenation Research".   Aubrey sees life extension as a side effect of his efforts to make people healthier, and sees no inherent limit to how far this could ultimately extend. We explore such concepts the "pro aging trance", "longevity escape velocity" and "comprehensive damage repair" that can sustain a human body.   More on Aubrey and the SENS Research Foundation: https://www.sens.org   More at: https://www.MindAndMachine.io

Are you interested in space travel, genetic engineering and other futurist tech trends transforming our world/society? If so you will love this.Our Expert Panelists:Aubrey de Grey is a Cambridge researcher and Chief Science Officer of SENS Research Foundation focused on aging and extending human longevity. He proposes that the first human beings who will live to 1,000 years old have already been born. In addition to his research, Aubrey is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging(2007). De Grey’s research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls “Strategies for Engineered Negligible Senescence” (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage.Mike Selden is co-founder and CEO of Finless Foods, a food startup that uses cutting-edge cellular-agriculture technologies to grow marine-animal cells, creating fish and seafood products enjoyed around the world. They are working toward a sci-fi, soon-here world where everyone has access to healthy, delectable seafood, without the environmental devastation or the health hazards of traditional fishing and aquatic farming.Jenny Rooke is the founder and managing partner or Genoa Ventures (formerly 5 Prime Ventures) where she funds and builds companies that change the way science gets done with new tools and technologies. She has a PhD in Genetics, a Bachelors in physics, and a background in computer science and works closely with early-stage life science start-ups on issues of fundraising, market and product strategy, and business development.We cover a wide range of topics from genetic engineering and human longevity to personalized medicine, pharma, manufactured meats and much more...You can listen right here on iTunes--Make a Tax-Deductible Donation to Support FringeFMFringeFM is supported by the generosity of its readers and listeners. If you find our work valuable, please consider supporting us on Patreon, via Paypal or with DonorBox powered by Stripe.Donate

Aubrey de Grey (@aubreydegrey) is Cambridge researcher and Chief Science Officer of SENS Research Foundation focused on aging and extending human longevity. He proposes that the first human beings who will live to 1,000 years old have already been born. In addition to his research, Aubrey is editor-in-chief of the academic journal Rejuvenation Research, author of... The post FringeFM 18 – Aubrey de Grey on the End of Aging, Increased Human Longevity and Living to 1000 Years appeared first on The Syndicate.

Aubrey de Grey (@aubreydegrey) is Cambridge researcher and Chief Science Officer of SENS Research Foundation focused on aging and extending human longevity. He proposes that the first human beings who will live to 1,000 years old have already been born.In addition to his research, Aubrey is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007).  De Grey's research focuses on whether regenerative medicine can prevent the aging process. He works on the development of what he calls "Strategies for Engineered Negligible Senescence" (SENS), a collection of proposed techniques to rejuvenate the human body and stop aging. To this end, he has identified seven types of molecular and cellular damage caused by essential metabolic processes. SENS is a proposed panel of therapies designed to repair this damage.He has been interviewed by most major news sources, including CBS 60 Minutes, the BBC, The New York Times, Fortune Magazine, The Washington Post, TED, Popular Science, The Colbert Report, Time and the Skeptics' Guide to the Universe.You can listen right here on iTunesIn our wide-ranging conversation, we cover many things, including: * Why Aubrey switched from studying AI to the science of human longevity * The causes of aging and how we can "cure" them * Why prevention is orders of magnitude more effective than intervention * The reason Aubrey believes some humans today will live to be 1000 years old * Why there isn't enough funding or support currently for fighting aging * The reason stem cell research is progressing rapidly and proving fruitful * How caloric restriction effects metabolism and aging * Why SENS often spins out businesses to further their aims * The science of immortality * How mainstream media has reacted to prospect of increasing lifespanTranscriptProducing this podcast and transcribing the episode takes tons of time and resources. If you support FringeFM and the work we do, please consider making a tax-deductible donation. If you can’t afford to support us, we completely understand as well, but an iTunes review or share on Twitter can go a long way too! AUBREY DE GREY:  Well I do think it’s very probable. In fact, I think it’s quite likely that the first person to live to a thousand is already in their forties or fifties—or, and perhaps even older.  So the question is, “Why do I think that?” And a lot of people misunderstand this. Some people think that the reason I’m saying this is because I think that we are within a small number of decades of developing therapies that completely, one hundred percent eliminate aging by repairing every single aspect of the damage that the body accumulates as  a side effect of its normal operation. I don’t say that at all. I never have, and I never shall.  MATT:  Survival of the fittest—Darwin realized evolution is merely the process of survival.  Nothing has been more driving a force as survival. Nothing wants to die. I don’t want to die.  You don’t want to die—even if you’ve accepted death. When there’s a way around it, we would give anything.  Today we’ve got Aubrey de Grey. Aubrey’s the Cambridge researcher and chief science officer of th...

Sought after guest speaker, Aubrey de Grey, has appeared on numerous popular programs including CBS 60 Minutes, BBC, TED and The Colbert Report to name just a few. Today, he joins The Future Tech Podcast, to share his vision on how we can improve the aging process through enhancing the human body's capability of rejuvenation through cell immortality and pluripotency to human aging and age-related disease. The. Vice President of New Technology and Discovery at AgeX Therapeutics, Aubrey de Grey, Ph.D., is also the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) biomedical research charity that performs, and funds research devoted to battling the progression of aging. In this fascinating discussion, Aubrey explains some of the obstacles that need to be overcome, including issues involving age-related tissue damage and stem cell decline which contribute to accelerating the aging process. He also discusses what AgeX is doing in stem cell research and in regenerative medicine that will improve not only the longevity of life, but also the quality and health of individuals throughout the aging process. He also touches on what he sees could be the future in the science of aging and treatments being worked on by the rejuvenation research community. For more information, visit: www.agexinc.com

Aubrey de Grey is a biomedical gerontologist, and the Chief Science Officer of SENS Research Foundation, a California based non-profit charity dedicated to combating the aging process. Through his work at SENS, Aubrey works on the development of medical innovations that promote rejuvenation and can postpone all forms of age-related ill-health including diseases like alzheimers, certain forms of cancer and atherosclerosis. Aubrey started off as a computer scientist and AI Researcher before becoming a self-taught bio gerontologist, which makes him a fascinating example of someone who can pick up new skills and develop deep knowledge in new fields In this conversation we discuss: - The transferability of research as a skill and the multidisciplinary nature of innovation - The core ideas behind Aubrey’s research – and what that means for the future of human aging - How to successfully spread your message to attract interest to your work Aubrey has a love for bold statements and is often a magnet for controversy in the media, but he’s a remarkably flexible and original thinker, so whether you're curious about the future of human aging or want to learn more about how to communicate effectively in a world full of noise, this episode has you covered.

The Sunday Times’ tech correspondent Danny Fortson brings on Aubrey de Grey, founder of the Sens Research Foundation, to talk the possibility of turning humans into a "multi-century species" (1:40), why rejuvenation is the key (4:40), aiming for “longevity escape velocity” (6:00), what’s wrong with the current approach to ageing, tackling the seven types of ageing damage (10:20), why the Google guys are wasting their money (11:30), getting funding from Peter Thiel and Vitalik Buterin (13:35), why cryptocurrency millionaires are enthused by living forever (15:25), why eternal life is the next step in evolution (18:45), what rejuvenation looks like (23:25), why he has no time for dystopic predictions (27:00), the coming war on ageing (31:20), how he ended up in Silicon Valley (35:45), why ageing doesn’t get much funding (38:20), and treating the human body like a car (39:30). See acast.com/privacy for privacy and opt-out information.

Dr. Aubrey de Grey is a biological gerontologist on a crusade to defeat aging. He thinks we are within a couple of decades of rejuvenation medicine capable of adding another 30 years to human lifespan, proposing that the first person to live to 1,000 years old may already be alive today. In the field of longevity science, there are a few roadblocks, but the biggest one is funding. They discuss why it isn’t a higher priority for average people to further this research.   Mark and Dr. de Grey cover a number of concepts at the forefront of anti-aging, such as whether increasing telomere lengths may be beneficial against aging or may cause side effects. Dr. de Grey suggests we learn more about the subject of defeating aging. Then become an advocate for the research, to bring about these medicines faster. Mark also asks Dr. de Grey about the morality of pursuing greater longevity for humans. Also on the podcast, Mark and Dr. Gladden discuss how the typical medical approach isn’t designed to promote longevity but treat the immediate problem. Medicine is still, after all, a business. Reimbursement is always going to trump research. They consider de Grey’s focus on finding a big breakthrough, versus the approach of making what you have better now, along the way. For more information on This Week in Longevity Science, visit https://news.osu.edu/news/2017/08/07/regenerative-med-study/. Dr. Gladden expands on the function of stem cells in regard to these new findings. Ask yourself, “How does it change your thinking about the structure of your family, your work, community, etc., when you consider the ability to live 120 robust years?” About the guest: Dr. de Grey is the biomedical gerontologist who researched the idea for and founded SENS Research Foundation. Learn more at http://www.sens.org/. He received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. Dr. de Grey is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations.  Follow de Grey on Twitter @AubreydeGrey and Facebook: https://www.facebook.com/drdegrey/

Dr. De Grey is a biomedical gerontologist who researched the idea for and founded SENS Research Foundation. SENS Research Foundation is a public charity that is transforming the way the world researches and treats age-related disease. SENS asserts that two thirds of all deaths worldwide, and about 90% of all deaths in the developed world, are from causes that only rarely kill young adults. If we look at the entire world, then the number of deaths that occur each day is roughly 150,000 and about two-thirds of them are because of aging. These causes include Alzheimer's, cardiovascular disease, Type II diabetes and most cancers. They are age-related because they are expressions of the later stages of aging, occurring when the molecular and cellular damage that has accumulated in the body throughout life exceeds the level that metabolism can tolerate. Before it kills us, aging, imposes on most elderly people, a long period of decline, debilitation and disease. For these reasons, aging is unarguably the most prevalent medically-relevant phenomenon in the modern world and the primary ultimate target of biomedical research. In this episode, we have the distinct honor and privilege to talk to one of the world’s foremost experts on aging and learn about his assertion that the first human beings who will live to be 1,000 years old have already been born.

Aubrey de Grey shares his perspective as chief science officer of the SENS Research Foundation where he directs research on regenerative therapies to thwart the aging process. (Originally released 4/3/15)

Phil and Stephen continue their discussion with Dr. Aubrey de Grey, reviewing some of the very encouraging life extension research currently taking place How does the treatment of other conditions (cancer, diabetes, obesity, heart disease, etc) ultimately contribute to the first generation of anti-aging medicine?Will devices such as those created for the Qualcomm Tricorder X Prize be a game-changer for treating aging? What role will CRISPR technology play in helping us to live longer?Metformin -- miracle youth drug or a lot of hype?Of the seven kinds of cell damage that constitute aging, which are we gaining on with the current research?And which is the most challenging? About Our Guest: Dr. Aubrey de Grey is a biomedical gerontologist who researched the idea for and founded the SENS Research Foundation. SENS stands for “Strategies for Engineered Negligible Senescence,” an idea that Aubrey outlined in his 2007 book, Ending Aging. Aubrey has a BA in Computer Science and a Ph.D. in Biology from the University of Cambridge. He is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations. He is also a contributor to our book Visions for a World Transformed. WT 327-636

Phil and Stephen welcome life extension researcher and visionary Dr. Aubrey de Grey to discuss the sometimes puzzlingly negative views much of the public seem to have about efforts to fight aging. Topics: A question Aubrey raises in Visions for a World Transformed:  What possesses people to defend the existence of the phenomenon that is far and away the most likely thing to kill them – and not only that, but to do so slowly and painfully? How is it that the elderly are themselves guilty of ageism? Glenn Reynolds in USA Today What is the pro-aging trance? Methuselah Mouse project as proof of concept for fighting aging Is life extension becoming more mainstream?  Is the first human being who will live to the age of 1,000 already among us? About Our Guest: Dr. Aubrey de Grey is a biomedical gerontologist who researched the idea for and founded the SENS Research Foundation. SENS stands for “Strategies for Engineered Negligible Senescence,” an idea that Aubrey outlined in his 2007 book, Ending Aging. Aubrey has a BA in Computer Science and a Ph.D. in Biology from the University of Cambridge. He is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations. He is also a contributor to our book Visions for a World Transformed. WT 326-635  

Aging could become a thing of the past. Not in 100 years, but within our lifetime (whatever that means) In this episode, I'm joined by Aubrey de Grey. Aubrey is a British biomedical gerontologist, chief scientist and founder of the SENS Research Foundation, an institution focused on using regenerative medicines to repair damage underlying the diseases of aging. In our conversation, we talk about some of the underlying causes of aging, where anti-aging research is at the moment, and what the near future might look like in the industry. Support the podcast at: talkoftoday/support patreon.com/talkoftoday Support this podcastSupport this podcast at — https://redcircle.com/talk-of-today/donations

Clearly throughout recorded history we’ve been fascinated by things like the Fountain of Youth and anything that would reverse the aging process. Let’s face it, if you’re over 40, you feel it physically. Your systems just start to break down. In modern medicine, this process has been seen as disease but this week’s guest, Aubrey de Grey, sees it more like an engineering challenge. Aubrey is a very controversial biomedical gerontologist and crusader against aging. He has a very specific plan that identifies the various components that cause human tissue to age, and he has very specific remedies for each of them. That’s what his non-profit, The SENS Research Foundation (a 501C-3) focuses on and it’s got some interesting people behind it, like Peter Thiel (one of the founders of PayPal) and Aubrey himself who has invested a large part of his inheritance to the cause.  Grow Big Always often has conversations with rebels that help us reshape the points of view that we take for granted, so Aubrey de Gray is a perfect guest. I hope you enjoy this conversation we had via Skype. Maybe you’ll end up agreeing with him— that the person that ends up living to 1,000 years old has already been born today. 

In this episode we explore technological challenges and solutions for extending the human life span and contemplate some of the challenges an extended lifespan might pose for our civilization. Visit the SENS Research Foundation: http://www.sens.org Watch the video version: https://youtu.be/kKmdc2AuXec Visit our Website: http://www.isaacarthur.net Join the Facebook Group: https://www.facebook.com/groups/1583992725237264/ Support the Channel on Patreon: https://www.patreon.com/IsaacArthur Visit the sub-reddit: https://www.reddit.com/r/IsaacArthur/ Cover Art by Jakub Grygier: https://www.artstation.com/artist/jakub_grygier

Biohacking, nootropics, and the notion of optimizing one's human performance are on a rapid rise. Nootrobox founders Geoffrey Woo and Michael Brandt are some of the foremost thinkers in this space, and they are here to have intellectual conversations that will make you THINK. Episode 9 features Aubrey de Grey, the Chief Scientist Officer of the SENS Research Foundation. In this episode, Geoff, Michael, and Aubrey discuss the nuances of aging and health and their differing opinions and tactics of how to fully optimize these notions. Nootrobox Twitter: twitter.com/nootrobox Nootrobox Instagram: www.instagram.com/nootrobox/ SUBSCRIBE for updates on the latest Nootrobox content! ⚡️

Biohacking, nootropics, and the notion of optimizing one's human performance are on a rapid rise. Nootrobox founders Geoffrey Woo and Michael Brandt are some of the foremost thinkers in this space, and they are here to have intellectual conversations that will make you THINK. Episode 9 features Aubrey de Grey, the Chief Scientist Officer of the SENS Research Foundation. In this episode, Geoff, Michael, and Aubrey discuss the nuances of aging and health and their differing opinions and tactics of how to fully optimize these notions. Nootrobox Twitter: twitter.com/nootrobox Nootrobox Instagram: www.instagram.com/nootrobox/ SUBSCRIBE for updates on the latest Nootrobox content! ⚡️

Dr. Aubrey de Grey is a biomedical gerontologist based in Cambridge, UK and Mountain View, California, USA. He is the Chief Science Officer of SENS Research Foundation, a California-based biomedical research charity that performs and funds laboratory research dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world's highest-impact peer-reviewed journal focused on intervention in aging. On today's episode of Bulletproof Radio, Dave and Aubrey talk about the seven things that cause aging, morbidity, the ethics of immortality, fighting cancer, aging goals for the immediate future and more. Enjoy the show!

Dr. Aubrey de Grey is a biomedical gerontologist based in Cambridge, UK and Mountain View, California, USA. He is the Chief Science Officer of SENS Research Foundation, a California-based biomedical research charity that performs and funds laboratory research dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world's highest-impact peer-reviewed journal focused on intervention in aging. On today's episode of Bulletproof Radio, Dave and Aubrey talk about the seven things that cause aging, morbidity, the ethics of immortality, fighting cancer, aging goals for the immediate future and more. Enjoy the show!

Topic: Fifty Years of SETI--Where is Everyone? Our speaker is Robert Buetner, the award-winning author of more than ten novels, a former intelligence officer, paleontologist, and lawyer. [News Item] Lifespan.io is a new crowdfunding platform dedicated specifically to research aimed at extending healthy human lifespan. Through centralizing such crowdfunding efforts, it can help create a powerful grassroots movement to overcome age-related disease—both by building a community of passionate donors who can fund research directly and by providing an accessible gateway for the public at large to be introduce to the idea of life extension. The first campaign, from the SENS Research Foundation, is already over 50% funded, and more projects will be launching soon. Please visit www.Lifespan.io to join the cause, and help #CrowdfundTheCure for aging. Hosted by Stephen Euin Cobb, this is the September 9, 2015 episode of The Future And You. [Running time: 37 minutes] This discussion was recorded in front of an audience at the science fiction and fantasy convention LibertyCon in Chattanooga TN, on June 27, 2015. Stephen Euin Cobb has interviewed over 350 people for his work as an author, futurist, magazine writer, ghostwriter, and award-winning podcaster. A contributing editor for Space and Time Magazine; he has also been a regular contributor for Robot, H+, Grim Couture and Port Iris magazines; and he spent three years as a columnist and contributing editor for Jim Baen's Universe Magazine. For the last nine years he has produced a weekly podcast, The Future And You, which explores (through interviews, panel discussions and commentary) all the ways the future will be different from today. He is an artist, essayist, game designer, transhumanist, and is on the Advisory Board of The Lifeboat Foundation. Stephen is the author of an ebook about the future entitled: Indistinguishable from Magic: Predictions of Revolutionary Future Science.

Last week we attended the 2015 Rejuvenation Biotechnology Conference where we heard about the latest developments in aging research. We were fortunate enough to sit down with two of the major figures in the field of aging research, Aubrey de Grey, CSO of the SENS Research Foundation and Brian Kennedy, CEO of the Buck Institute for Research on Aging. Brian and Aubrey have gone about their work in different ways but say that their approaches are now converging as the momentum behind aging research increases.

Dr. Aubrey de Grey is a biomedical gerontologist who is the Chief Science Officer and Cofounder of SENS Research Foundation found at Sens.org. They work to extend the lifespan significantly. They believe the first person that will live to 1000 is alive today. He received a degree in  Computer Science and Ph.D. in Biology from the University of Cambridge. Dr. de Grey is Editor-in-Chief of Rejuvenation Research  and sits on numerous scientific advisory boards and journals. He is the author of  “Ending Aging”.   http://www.inspiredinsider.com/aubrey-de-grey-endaging-interview/  

Aubrey de Grey is an English author and theoretician in the field of gerontology and the Chief Science Officer of the SENS Research Foundation.

Aubrey de Grey is an English author and theoretician in the field of gerontology and the Chief Science Officer of the SENS Research Foundation. http://sens.org/

  Dr. Aubrey de Grey is Co-Founder and Chief Science Officer at the SENS Research Foundation, a not for profit dedicated to defeating age-related disease. 

Rejuvenating hot tubs, the possibility of humans living for 1,000 years, and a global crusade to defeat aging. In this episode, I talk to scientist Aubrey de Grey, biomedical gerontologist who serves as the Chief Science Officer and Co-founder of the SENS Research Foundation, which is working to change the way the world researches and treats age-related disease.   Music Show Opening Mix: Brand New – Salt-n-Pepa / Brand New – Pharrell Williams (with Justin Timberlake) / Brand New Key – Melanie / Brand New – Kanye West (feat. Rhymefest) On Aging – Maya Angelou When I’m Sixty-Four – The Flaming Lips (feat. Def Rain & Pitchwafuzz) Show Closing Mix: Brand New Funk – DJ Jazzy Jeff & The Fresh Prince / Brand New You’re Retro – Tricky / Brand New Me – Dusty Springfield / Brand New Me – Isaac Hayes   Reading List Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime - by Aubrey de Grey   Watch List: The Immortalists

Guest: Aubrey de Grey, CoFounder, CSO, SENS Research Foundation Bio and Contact Info Chapters: (Advance the marker) 0:35 First Rejuvenation Biotechnology Conference 4:50 Shackled by “short-termism” 6:00 Aging was not a topic for biologists 11:32 A serious nuisance 17:13 Smoking out the opposition