Podcasts about evaluation ihme

The last Lancet Voice of the year delves into the latest findings from the Institute for Health Metrics and Evaluation (IHME) from our recently released US Special Issue. Ali Mokdad and Emmanuela Gakidou join Miriam Sabin and Gavin Cleaver to explore the comprehensive analysis of the Global Burden of Disease, the alarming trends in obesity and life expectancy, and the critical need for policy changes to improve public health in the United States.Read the US special issue here:https://www.thelancet.com/journals/lancet/issue/vol404no10469/PIIS0140-6736(24)X0050-1?dgcid=buzzsprout_tlv_podcast_generic_lancetSend us your feedback!Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancetCheck out all the podcasts from The Lancet Group:https://www.thelancet.com/multimedia/podcasts?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

De acuerdo con el Institute for Health Metrics and Evaluation (IHME), más de 145 millones de personas en todo el mundo tuvieron covid largo en 2020 y 2021, y muchas personas reportan que después de 4 años, ya no fueron los mismos, que si todo se les olvida, que siempre están agotados… Viene Paco Morenos a explicarnos más sobre el Long Covid. Hosted on Acast. See acast.com/privacy for more information.

De acuerdo con el Institute for Health Metrics and Evaluation (IHME), más de 145 millones de personas en todo el mundo tuvieron covid largo en 2020 y 2021, y muchas personas reportan que después de 4 años, ya no fueron los mismos, que si todo se les olvida, que siempre están agotados… Viene Paco Morenos a explicarnos más sobre el Long Covid. Hosted on Acast. See acast.com/privacy for more information.

HEALTH NEWS   ·         Intermittent fasting improves Alzheimer's pathology ·         Melatonin and its derivatives found to enhance long-term object recognition memory ·         Heat therapy boosts mitochondrial function in muscles ·         Too young for arthritis? 15% of global population over age 30 have condition ·         Decreased acetyl-L-carnitine levels associated with depression ·         Floatation Therapy for Specific Health Concerns      Intermittent fasting improves Alzheimer's pathology  University of California San Diego School of Medicine, August 21, 2023 One of the hallmarks of Alzheimer's disease is disruption to the body's circadian rhythm, the internal biological clock that regulates many of our physiological processes. Nearly 80% of people with Alzheimer's experience these issues, including difficulty sleeping and worsening cognitive function at night. However, there are no existing treatments for Alzheimer's that target this aspect of the disease. A new study from researchers at University of California San Diego School of Medicine has shown in mice that it is possible to correct the circadian disruptions seen in Alzheimer's disease with time-restricted feeding, a type of intermittent fasting focused on limiting the daily eating window without limiting the amount of food consumed. In the study, published in Cell Metabolism, mice that were fed on a time-restricted schedule showed improvements in memory and reduced accumulation of amyloid proteins in the brain. The authors say the findings will likely result in a human clinical trial. “Circadian disruptions in Alzheimer's are the leading cause of nursing home placement,” said Desplats. “Anything we can do to help patients restore their circadian rhythm will make a huge difference in how we manage Alzheimer's in the clinic and how caregivers help patients manage the disease at home.” Compared to control mice who were provided food at all hours, mice fed on the time-restricted schedule had better memory, were less hyperactive at night, followed a more regular sleep schedule and experienced fewer disruptions during sleep. The test mice also performed better on cognitive assessments than control mice, demonstrating that the time-restricted feeding schedule was able to help mitigate the behavioral symptoms of Alzheimer's disease. The researchers also observed improvements in the mice on a molecular level. In mice fed on a restricted schedule, the researchers found that multiple genes associated with Alzheimer's and neuroinflammation were expressed differently. They also found that the feeding schedule helped reduce the amount of amyloid protein that accumulated in the brain. Amyloid deposits are one of the most well-known features of Alzheimer's disease.     Melatonin and its derivatives found to enhance long-term object recognition memory Sophia University (Japan), August 21, 2023 Multiple studies have demonstrated the memory-enhancing effects of melatonin and its derivatives in animal models. It is also known that the formation of both short- and long-term memories require the phosphorylation of certain memory-related proteins. However, the molecular mechanisms underlying melatonin-induced memory enhancement have remained elusive. Now, medical researchers from Sophia University, Japan, have made important findings that contribute significantly to the elucidation of the underlying mechanisms in a recent article that was published NeuroReport on June 7, 2023. The research team, which included Dr. Masahiro Sano (currently affiliated with Tohoku University) and Dr. Hikaru Iwashita (currently affiliated with Kansai Medical University), examined the effects of three compounds on memory formation; these compounds were melatonin, a hormone secreted by the pineal gland located in the brain; N1-acetyl-5-methoxyquinuramine (AMK), melatonin's biological metabolite; and ramelteon, a drug that binds and activates the melatonin receptor. Initial experiments conducted on male mice clearly showed that the administration of melatonin, ramelteon, or AMK at a dose of 1 mg/kg facilitated the formation of long-term memory. The researchers did not investigate the effects of the three compounds on female mice to avoid any likely data variability resulting from the reproductive cycles occurring in female mammals. Prof. Chiba concludes, "Our findings suggest that melatonin is involved in promoting the formation of long-term object recognition memory by modulating the phosphorylation levels of memory-related proteins such as ERK, CaMKIIs, and CREB in both receptor-mediated and nonreceptor-mediated signaling pathways."   Heat therapy boosts mitochondrial function in muscles Brigham Young University, July 31, 2023 A new study finds that long-term heat therapy may increase mitochondrial function in the muscles. The discovery could lead to new treatments for people with chronic illness or disease.  Mitochondria, the "energy centers" of the cells, are essential for maintaining good health. Exercise has been shown to create new mitochondria and improve function of existing mitochondria. However, some people with chronic illnesses are not able to exercise long enough--previous research suggests close to two hours daily--to reap the benefits. Rodent studies have suggested that heat exposure may also induce the production of more mitochondria. Researchers from Brigham Young University in Utah studied 20 adult volunteers who had not participated in regular exercise in the three months prior to the study. The research team applied two hours of shortwave diathermy--a type of heat therapy generated by electrical pulses--to the thigh muscles of one leg of each person every day. The researchers based the six-day trial of heat on the minimum amount of exercise needed to measure changes in muscle, or about two hours each day. They designed the treatment to mimic the effects of muscle heating that occurs during exercise.  Mitochondrial function increased by an average of 28 percent in the heated legs after the heat treatment. The concentration of several mitochondrial proteins also increased in the heated legs, which suggests that "in addition to improving function, [repeated exposure to heat] increased mitochondrial content in human skeletal muscle," the research team wrote. "Our data provide evidence to support further research into the mechanisms of heat-induced mitochondrial adaptations," the researchers explained. People who are not able to exercise for long periods of time due to their health may benefit from [heat] treatments.   Too young for arthritis? 15% of global population over age 30 have condition Institute for Health Metrics and Evaluation (US), August 21, 2023 Arthritis is just a problem for the elderly, right? Not so fast. A recent study finds that osteoarthritis affects 15 percent of individuals over the age of 30 worldwide. Contributing factors include obesity, as well as an aging and growing global population. Remarkably, excess weight is responsible for 20 percent of these cases. Moreover, for those over 70, osteoarthritis ranks as the seventh leading cause of years people live with a disability. Experts forecast that by 2050, one billion people will be afflicted by this condition. Women tend to be more susceptible than men. The most commonly impacted areas include the hands, hips, knees, and other joints like the shoulders and elbows. By 2050, estimates predict a 78.6-percent increase in hip pain cases, 75 percent in the knee, 50 percent in the hand, and a staggering 95.1-percent increase in other areas. This research, led by the Institute for Health Metrics and Evaluation (IHME) in Seattle, assessed three decades of osteoarthritis data from over 200 countries. In 1990, the global count was 256 million individuals with osteoarthritis. By 2020, this number skyrocketed to 595 million, marking a 132-percent increase from 1990. The dramatic rise can be attributed to three primary causes: aging, population growth, and the obesity epidemic. The team's findings underscored the mounting influence of obesity over time as its rates have soared. They estimate that effectively addressing obesity could reduce the osteoarthritis burden by one-fifth.   Decreased acetyl-L-carnitine levels associated with depression Stanford University, July 30 2023  An article that appeared in the Proceedings of the National Academy of Sciences reported a link between low levels of acetyl-L-carnitine and a greater risk of depression. Acting on the findings of animal research conducted by lead author Carla Nasca, PhD, the researchers recruited men and women between the ages of 20 and 70 years who had been admitted to Weill Cornell Medicine or Mount Sinai School of Medicine for treatment of acute depression. Clinical assessments were conducted upon enrollment and blood samples were analyzed for levels of acetyl-L-carnitine. In comparison with levels measured in blood samples provided by 45 demographically matched healthy men and women, acetyl-L-carnitine blood levels in depressed subjects were substantially lower. Acetyl-L-carnitine levels were lowest among depressed patients who had severe symptoms, a history of treatment resistance, or early onset disease. Having a history of childhood abuse was also associated with low acetyl-L-carnitine levels. "We've identified an important new biomarker of major depression disorder,” Dr Rasgon stated. “We didn't test whether supplementing with that substance could actually improve patients' symptoms. What's the appropriate dose, frequency, duration? This is the first step toward developing that knowledge, which will require large-scale, carefully controlled clinical trials."   Floatation Therapy for Specific Health Concerns  Medical University of South Carolina, August 6, 2023 We conducted a search of multiple databases using the following search terms: float, floatation therapy, floatation REST, isolation tank, stress, relaxation response, magnesium sulfate, transdermal magnesium, cortisol, pain, depression, anxiety, sleep, and addiction.  The reviewed studies revealed benefits of floating, specifically regarding participants experiencing muscular pain, depression, anxiety, stress, and sleep disorders. Long-term benefits appear variable. Traditionally, isolation tanks are enclosed to inhibit light and sound as much as possible and reduce all incoming stimuli. The float experience minimizes sensory signals including visual, auditory, olfactory, thermal, tactile, and gravitational.  The studies discussed were conducted with the combination of water and Epsom salt. The salt-saturated water in most commercial centers is cleaned with a filtration system that runs between each session, in addition to manual skimming and treatment with ultraviolet light, hydrogen peroxide, and ozone. Generally, a float session lasts for 60 minutes, although it can be shorter or longer. The benefits of magnesium sulfate (MgSO4), better known as Epsom salt, are well known. The World Health Organization (WHO) lists it as an essential medication.   A proposed mechanism of action of the aforementioned benefits of floatation therapy lies in the transdermal absorption of MgSO4. Given the selectivity of the stratum corneum layer of the skin and the ionic nature of elemental magnesium, it appears that specific lipophilic carriers are required for MgSO4 to cross the dermal layer into the circulation. Among the benefits the analysis of studies suggest include: Pain:  Kjellgren and colleagues found a significant improvement with floatation therapy in those who experienced the most intense muscle pain (P=0.004), but there was no benefit found in participants who experienced lower levels of pain. There were 37 participants in this study, all of whom had chronic muscular pain of the neck and back regions. Individuals floated 9 times during a 3-week period. Of the 32 participants in this study, 22% became pain-free, 56% had improvement of pain, 19% experienced no increase or decrease of pain, and 3% experienced worsening of pain. Depression and Anxiety:  At the Laureate Institute for Brain Research in Tulsa, Oklahoma, researchers have extensively studied floatation therapy, particularly in the areas of depression and generalized anxiety disorder (GAD). One study involving 50 participants at LIBR examined the anxiolytic and antidepressant effects of floating. Results showed a significant reduction in anxiety among participants, regardless of gender. All changes were significant. Anxiety and stress-related disorders in this study included post-traumatic stress disorder, generalized anxiety disorder, panic disorder, agoraphobia, and social anxiety disorder. In addition to reduced anxiety, there was a significant improvement in mood characterized by “serenity, relaxation, happiness, positive affect, overall well-being, energy levels, and feeling refreshed, content and peaceful.” Stress:  Research generally finds floatation therapy to be beneficial for stress reduction. The relaxation response (which is associated with the parasympathetic nervous system) occurs when floating, lowering blood pressure and lowering cortisol levels in some studies.  Sleep:  People have used floatation therapy to aid with sleep. Since magnesium is a common supplement used to aid with sleep, this is a logical area of float research interest. In a study looking at 19 athletes and floating, participants not only had improved athletic performance recovery, but also experienced significant improvements in having “deeper sleep, fewer awakenings during the night, and a sense of renewed energy upon awakening in the morning.”

The Global Burden of Disease Study (GBD) began in 1991 sponsored by the World Bank and the World Health Organization to fill a critical gap in global health information. It has grown steadily to become an active collaboration of more than 8,000 scientists, researchers and policy-makers from 156 countries working together to quantify health at the national and subnational level. In this program, Christopher J.L. Murray, Professor and Chair of Health Metrics Sciences at the University of Washington and Director of the Institute for Health Metrics and Evaluation (IHME), discusses what we've learned over the last 30 years studying global health. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Health and Medicine] [Show ID: 38270]

The Global Burden of Disease Study (GBD) began in 1991 sponsored by the World Bank and the World Health Organization to fill a critical gap in global health information. It has grown steadily to become an active collaboration of more than 8,000 scientists, researchers and policy-makers from 156 countries working together to quantify health at the national and subnational level. In this program, Christopher J.L. Murray, Professor and Chair of Health Metrics Sciences at the University of Washington and Director of the Institute for Health Metrics and Evaluation (IHME), discusses what we've learned over the last 30 years studying global health. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Health and Medicine] [Show ID: 38270]

The Global Burden of Disease Study (GBD) began in 1991 sponsored by the World Bank and the World Health Organization to fill a critical gap in global health information. It has grown steadily to become an active collaboration of more than 8,000 scientists, researchers and policy-makers from 156 countries working together to quantify health at the national and subnational level. In this program, Christopher J.L. Murray, Professor and Chair of Health Metrics Sciences at the University of Washington and Director of the Institute for Health Metrics and Evaluation (IHME), discusses what we've learned over the last 30 years studying global health. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Health and Medicine] [Show ID: 38270]

The Global Burden of Disease Study (GBD) began in 1991 sponsored by the World Bank and the World Health Organization to fill a critical gap in global health information. It has grown steadily to become an active collaboration of more than 8,000 scientists, researchers and policy-makers from 156 countries working together to quantify health at the national and subnational level. In this program, Christopher J.L. Murray, Professor and Chair of Health Metrics Sciences at the University of Washington and Director of the Institute for Health Metrics and Evaluation (IHME), discusses what we've learned over the last 30 years studying global health. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Health and Medicine] [Show ID: 38270]

The Global Burden of Disease Study (GBD) began in 1991 sponsored by the World Bank and the World Health Organization to fill a critical gap in global health information. It has grown steadily to become an active collaboration of more than 8,000 scientists, researchers and policy-makers from 156 countries working together to quantify health at the national and subnational level. In this program, Christopher J.L. Murray, Professor and Chair of Health Metrics Sciences at the University of Washington and Director of the Institute for Health Metrics and Evaluation (IHME), discusses what we've learned over the last 30 years studying global health. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Health and Medicine] [Show ID: 38270]

The Global Burden of Disease Study (GBD) began in 1991 sponsored by the World Bank and the World Health Organization to fill a critical gap in global health information. It has grown steadily to become an active collaboration of more than 8,000 scientists, researchers and policy-makers from 156 countries working together to quantify health at the national and subnational level. In this program, Christopher J.L. Murray, Professor and Chair of Health Metrics Sciences at the University of Washington and Director of the Institute for Health Metrics and Evaluation (IHME), discusses what we've learned over the last 30 years studying global health. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Health and Medicine] [Show ID: 38270]

The Global Burden of Disease Study (GBD) began in 1991 sponsored by the World Bank and the World Health Organization to fill a critical gap in global health information. It has grown steadily to become an active collaboration of more than 8,000 scientists, researchers and policy-makers from 156 countries working together to quantify health at the national and subnational level. In this program, Christopher J.L. Murray, Professor and Chair of Health Metrics Sciences at the University of Washington and Director of the Institute for Health Metrics and Evaluation (IHME), discusses what we've learned over the last 30 years studying global health. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Health and Medicine] [Show ID: 38270]

In this podcast, Dr. Eeks chats with Dr. Christopher Murray about his recent article published in The Lancet (2022) titled The Global Burden of Cancer Attributable to Risk Factors, 2010-2019, a Systematic Analysis for the Global Burden of Disease Study 2019. This is the largest effort to date to determine the gobal burden of cancer due to risk factors. He will discuss what the global burden of disease study is, how he and his team estimated the burden of cancer, the risk factors and the assessment framework used to link specific cancers to specific risks, what percentage of cancer is attributed to risk factors, what the greatest risks are, differences in high income vs low income countries and public health implications. Dr. Murray is Chair of Health Metrics Sciences at the University of Washington and Director of the Institute for Health Metrics and Evaluation (IHME). He also leads the Global Burden of Disease collaboration ( a systemic effort to quantify the comparitive magnitude of health loss due to diseases, injuries and risk factors.)He is both a physician and a health economist and his work has led to innovative methods for strengthening health measurements, analyzing the performance of health systems and producing forecasts for the future state of health. During the COVID-19 pandemic, the White House, European Commission, WHO EURO and Africa CDC have used IHME forecasts and policy scenarios as sources of evidence. You can contact Dr. Eeks at bloomingwellness.com.Follow Dr. Eeks on Instagram here.Or Facebook here.Or Twitter.Subcribe to her newsletter here!Support the show

The effects of drinking is a constant news headline. Every month or so, there seems to be a new study released that weighs the benefits and risks of drinking alcohol. Is some level of alcohol good for your health or should everyone completely avoid drinking? On today's episode we invited two experts with differing views on alcohol consumption to help us examine the data and decide. Our guests: Emmanuela Gakidou, Professor of Health Metrics Sciences and Senior Director of Organizational Development and Training at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.   Eric Rimm, Professor of Epidemiology and Nutrition and Director of the Program in Cardiovascular Epidemiology at the Harvard T.H. Chan School of Public Health and Professor of Medicine at the Harvard Medical School.   

1. 南京大屠杀死难者国家公祭仪式举行︱Nanjing holds national memorial ceremony for Nanjing Massacre victims In front of the darkly-dressed crowd, China's national flag flew at half-mast as the country held its eighth national memorial ceremony Monday for the victims of the Nanjing Massacre.2021年12月13日是第八个南京大屠杀死难者国家公祭日，公祭仪式在侵华日军南京大屠杀遇难同胞纪念馆集会广场举行，现场庄严肃穆，国旗下半旗。At exactly 10:01 a.m., sirens started to blare and the city came to a halt. Drivers in the downtown area stopped their cars and honked; pedestrians paused for a minute of silence in remembrance of the victims.上午10点01分，南京市拉响防空警报，全场向南京大屠杀死难者默哀，汽车停驶鸣笛，行人就地默哀。The Nanjing Massacre took place when Japanese troops captured the city on Dec. 13, 1937. Over six weeks, they killed more than 300,000 Chinese civilians and unarmed soldiers in one of the most barbaric episodes of World War II.1937年12月13日，侵华日军制造了南京大屠杀惨案。六周时间里，大量平民及战俘被日军杀害，无数家庭支离破碎，遇难人数超过30万，是日军在二战中最惨绝人寰的暴行，是人类历史的至暗时刻。In 2014, China's top legislature designated Dec. 13 as the national memorial day for the victims of the Nanjing Massacre.2014年，国家最高立法机关通过决定，将12月13日确定为国家公祭日。2. 全球人口预计在2064年达到顶峰︱World population set to decline for the first time in centuries says studyAccording to a new study published in theLancet journal, the world population will decline for the first time in the next century.发表在《柳叶刀》杂志上的一项新研究表明，下个世纪全球人口将首次下降。The world's population is currently estimated to be at 7.8 billion people. According to the estimate, the global population would peak at around 9.7 billion in 2064. Then it will fall to 8.79 billion in 2100.目前，全球人口约为78亿。据预测，全球人口将在2064年达到峰值，约为97亿。然后在2100年下降到87.9亿。 Due to low birth rates and aging populations, up to 23 countries, including Japan, Thailand, Italy, Spain, Portugal, South Korea, and others, might see their populations fall by more than 50%.由于低出生率和人口老龄化，包括日本、泰国、意大利、西班牙、葡萄牙、韩国等在内的多达23个国家的人口可能会下降50%以上。China is the world's most populated country. But it will see its population drop from 1.4 billion in 2017 to 732 million in 2100.中国是目前世界上人口最多的国家。而到2100年，国内人口将从2017年的14亿下降到7.32亿。Lead study author and Professor of Global Health at the Institute for Health Metrics and Evaluation (IHME), Stein Emil Vollset, told IFLScience, “The last time that global population declined was in the mid 14th century, due to the Black Plague. If our forecast is correct, it will be the first time population decline is driven by fertility decline, as opposed to events such as a pandemic or famine.”研究牵头人、华盛顿大学健康指标与评估研究所全球健康教授斯坦因·埃米尔·沃尔赛特指出：“全球人口上一次下降是在14世纪中叶，是黑死病导致的。如果预测正确，这将是第一次由生育率下降而导致人口下降，而不是由于疫情或饥荒等原因。”The worldwide total fertility rate is likely to steadily drop, from 2.37 in 2017 to 1.66 in 2100. It is significantly below the minimum rate (2.1 live births per woman) necessary to maintain population levels, he added.全球总生育率或将稳步下降，从2017年的2.37下降到2100年的1.66，远低于维持人口水平所需的最低生育率——平均每位女性2.1的生育率。3. 疫情期间美国离职潮引发“劝留”面谈︱Employers roll out 'stay' interviews as record number of Americans walk off the jobAmericans are walking away from their jobs in record numbers as remote work has uncoupled jobs from geography, and droves of employees are re-evaluating the relationships they have with their employers.自从远程工作让员工摆脱了地域限制，美国的离职人数创下了历史新高，大批员工开始重新评估他们和雇主之间的关系。To keep workers happy and on the job, more companies are turning to “stay interviews,” one-on-one meetings with top performers to give those key people the chance to talk about what works, and what doesn't work, about their current jobs.为了让员工快乐地留下来工作，越来越多的公司开始进行“劝留面谈”，与业绩最突出的员工进行一对一会面，让这些业务骨干有机会谈一谈现在工作中哪些方面是有成效的，哪些是行不通的。 Managers who conduct stay interviews are coached to ask workers open-ended questions about what they like most about their jobs, what they dislike and under what events or circumstances they might leave.开展劝留面谈的主管人员会按照培训内容询问员工一些开放式问题，比如这份工作让他们最喜欢的是什么，他们不喜欢什么，以及在什么情境下他们会离职。Sometimes workers switch jobs in pursuit of higher salaries, but recruiters say a significant factor is the higher expectations of job candidates today when it comes to feeling seen and supported by their bosses.有时候员工跳槽是为了追求更高的薪酬，但是招聘人员指出了另一个重要因素，那就是现在求职者对于得到老板重视和支持的期待更高了。Other departures are spurred by chances to have more flexible hours, remote work or professional development opportunities.其他离职原因还包括想获得更多弹性工作时间、希望远程工作或谋求职业发展机会。Dave Carvajal, the CEO of Dave Partners, a tech industry recruiting firm, said small businesses, which struggle to compete with huge companies in salaries and benefits, have more at stake and tend to use processes like stay interviews more frequently.技术行业招聘公司Dave Partners的首席执行官戴夫·卡瓦哈尔表示：“对小公司来说，薪酬和福利竞争不过大企业，人才流失风险更高，劝留面谈次数往往更为频繁。”halt英 [hɔːlt]；美[hɔːlt] n. 停止；暂停half-mast英 [ˌhɑːf ˈmɑːst]；美[ˌhæf ˈmæst] n. 半旗；下半旗v. 下半旗adj. 半旗的fertility英 [fəˈtɪləti]；美[fərˈtɪləti] n. 生育力；富饶；丰富uncouple英 [ˌʌnˈkʌpl]；美[ˌʌnˈkʌpl] v. 使（二者）分离，分开；脱钩one-on-one英 [ˌwʌn ɒn ˈwʌn]；美[ˌwʌn ɑːn ˈwʌn] adj. 面对面的；一对一的

This episode of Ask Theory features Dr. John Wong, a Filipino epidemiologist with over 30 years of experience in epidemiology and health systems research. In 2016, he became the first Filipino to win the Roux Prize, an international award that honors innovation in the application of disease burden research, from the Institute for Health Metrics and Evaluation (IHME) of the University of Washington. He is a co-founder and current senior technical adviser of EpiMetrics, a public health research firm, where he continues to work with the Department of Health, IHME, and USAID, among others, in reforming the health system, while training and working with young researchers in public health. We talked about what Pinoys need to know about COVID-19 vaccines, what we can and can't do after getting the COVID-19 vaccine, how to prepare ourselves in case a family member gets infected, how COVID-19 variants affect vaccine effectiveness, why we're sure that COVID-19 vaccines are safe and that they weren't “rushed,” and more. This special episode was made possible by EpiMetrics, a Philippine-based health research institution, as part of a special initiative called Life Stages: How to Do Everything Again Differently.

In my first episode, I interview Dr. Vin Gupta, global health policy expert, Critical Care physician, and Affiliate Assistant Professor at the University of Washington Institute for Health Metrics and Evaluation (IHME). Dr. Gupta is also a frequent contributor on MSNBC. In our conversation, we talk about the current status of the COVID-19 pandemic and what the next couple months will look like. We also spoke about the long-term impacts of COVID-19 in addition to ways to make our healthcare system more equitable moving forward.

Chris Murray, the renowned modeler, joined us to share his year-end reflections. In this year unlike any other, Covid-19 pushed modeling onto new ground, as forecasting of individual and governmental behavior became essential to inform decisions in the near to medium term. It’s been “a steep learning curve.” Looking ahead to 2021, in Q1 and 2 we will see a profound pivot, as vaccinations are scaled, winter ends, government policies evolve, and immunity within the population rises. We should arrive at “a surprisingly decent place in June or July.” As we “bounce back to pre-Covid behavior,” it will be a “balancing act.” Success in reaching herd immunity rests on a campaign to get “the maybes,” upwards of 30 percent of the population, while the 15-20 percent of “straight refusers” won’t budge. A vitally important “lingering question:” will we have attained enough vaccine coverage that nothing terrible happens in the winter of 2021-2022?   Chris Murray is the Director of the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.

"Humanity has become a panic-driven, irrational, hysterical species" Roger W. Koops, a scientist and specialist in vaccines and viruses, is the author of three eye-opening essays published on the website of the American Institute for Economic Research (https://www.aier.org/staffs/roger-w-koops/), in which he discusses the corona pandemic: Don’t Live Your Life in a Bubble, 12 August 2020, or: A Scientist’s Plea: The World is Not a Safe Space (to the Younger Generations) A Primer for the Media on Viruses, Vaccines and COVID-19, 25 September 2020 The Year of Disguises, 16 October 2020 In these essays Koops, who spent his life working in the pharmaceutical industry, in particular on vaccine development for anthrax, HIV and smallpox, convincingly shows that the lockdowns established by governments all over the world are useless and destructive. “I believe we are in as great a crisis as a species as we have ever seen,” he writes. “The crisis is not from some seasonal virus, which is a health issue, but it is from ourselves and what we have devolved into as a species.” Humanity, he notes, has become a “panic-driven, irrational, hysterical species”. In this interview with journalist Karel Beckman, Koops explains why the COVID-19 virus should have been dealt with as we normally deal with influenza viruses – protect the elderly and weak, and for the rest live our lives as we always do, so we build up group immunity. He explains why face masks are not merely ineffective as a protection against viruses, but actually dangerous, as they become a source of contamination. He further argues that there is absolutely no need for most people to become vaccinated. Koops also argues that the pandemic has been an “induced panic”. In particular, he questions the extraordinary role played by Bill Gates, a long-time fanatical supporter of lockdowns (!). Gates is a huge sponsor of the WHO, key scientific research institutions and key media outlets (CNN, Financial Times, Guardian, BBC). For example, Gates’s foundation has poured tens of millions into Imperial College of London (ICI),the source of the notoriously incorrect models that induced the UK and US governments to carry out lockdowns, as well as $280 million into the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. IHME regularly issues outrageously alarming reports on COVID-19 which are uncritically reported on by the same influential media sponsored by Gates. Koops ends on a hopeful note: “The science is out there, the data are out there,” he says. “It is not being reported on by the media, but it is there, and when people see it, it will crumble the whole house of cards.” However, the damage that has been done – to people’s lives, the economy and to the trust people once had in politics, the media and science – will be incalculable. Deze video is geproduceerd door Café Weltschmerz. Café Weltschmerz gelooft in de kracht van het gesprek en zendt interviews uit over actuele maatschappelijke thema's. Wij bieden een hoogwaardig alternatief voor de mainstream media. Café Weltschmerz is onafhankelijk en niet verbonden aan politieke, religieuze of commerciële partijen. Waardeer je onze video's? Je kunt ons ondersteunen met een donatie via https://cafeweltschmerz.nl. Wil je op de hoogte worden gebracht van onze nieuwe video's? Klik hierboven dan op Abonneren! Wil je onze nieuwsbrief ontvangen in je mailbox? https://cafeweltschmerz.nl/nieuwsbrief/

We sat with Chris Murray for an intense conversation on IHME’s recent, startling (and controversial) forecast that the United States would experience a dramatic surge in Covid-19 infections and deaths by year’s end that will exceed the peak moments of April. Many of the drivers are behavioral – a decline in mask use, rising mobility, lower vigilance and social distancing. But the seasonality is what will truly turbocharge the pandemic. Why is that, and what gives confidence that seasonality will be so powerful? Why do we as a nation appear stuck on a roller-coaster, incapable of learning to stick with actions that work? Chris Murray is Director of the Institute for Health Metrics and Evaluation (IHME) and Chair, Department of Health Metrics Sciences, at the University of Washington

Wildfires are nothing new – they’ve been part of the west’s ecology for millennia. But burning fossil fuels and suppressing the burning of forests over the past century have led to larger, more frequent and ever-more catastrophic wildfires. And burning trees release carbon dioxide. California’s fires now are so big and fierce that they threaten to erase the state’s progress in reducing greenhouse gas emissions. And even for those miles from the flames, the smoke from raging wildfires presents an extra danger in the age of coronavirus. "How and when exposure to wildfire smoke increases the likelihood of infection with COVID-19, we’re still trying to figure that out," says Vin Gupta of the Institute for Health Metrics and Evaluation at the University of Washington. "But there is a clear symmetry between exposure and the likelihood of infection." Visit climateone.org/watch-and-listen/podcasts for more information on today's episode. Guests: Part 1: Wade Crowfoot, California Secretary of Natural Resources Julie Cart, Reporter, CalMatters Part 2: Leroy Westerling, Professor of Management of Complex Systems, University of California, Merced Part 3: Vin Gupta, Affiliate Assistant Professor of Health Metrics Sciences at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington Additional Interview: Lenya Quinn-Davidson, Director of the Northern California Prescribed Fire Council. This episode was recorded in August 2020.

As of Friday, the US COVID-19 death toll has surpassed 187,000, growing by more than 1,000 on Thursday, according to data from Johns Hopkins University. Meanwhile, the University of Washington's Institute for Health Metrics and Evaluation (IHME) said Thursday that its model now predicts almost 410,000 Americans will have died from the respiratory disease by January 1. The IHME model's death toll projections have grown considerably since it was launched in March, indicating that the pandemic has only gotten worse in the US. "On Wednesday the Trump administration announced a halt on evictions through the end of the year, a move that may shield the millions of Americans at risk of losing their homes due to the financial chaos sparked by the coronavirus pandemic," the Washington Post reported Thursday. "But the housing crisis that has built up since March - fueled by job losses and the end of federal benefits in July - has already injected the market with so much instability that even a national moratorium may only be a temporary pause." Is this a solution or just a temporary, stopgap measure for political gain? On Tuesday, "the ACLU of Georgia released a report by the Palast Investigative Fund titled 'Georgia Voter Roll Purge Errors' that concluded the State had likely removed in 2019 the voter registrations of nearly 200,000 Georgia citizens on the grounds that they had moved from the address on their voter registration application," according to a release from the American Civil Liberties Union (ACLU) of Georgia. What does this mean for the state of Georgia, and what does it indicate for the country?There are a number of issues that impact states and cities in the US. We will get some insight into how to manage these from our next guest, Jesse Ventura, a former professional wrestler who previously served as the 38th governor of Minnesota. He's also an actor, political commentator, bestselling author, US Navy veteran and the host of "The World According to Jesse" on RT America.Friday is panel day. Joining us are Dr. Clarence Lusane and Daniel Lazare to discuss the issues of rent relief, hunger, the government shutdown and Michael Forest Reinoehl.Guests:Dr. Yolandra Hancock - Physician, board-certified pediatrician and obesity medicine specialistDr. Lisa Lewis - Holder of a doctorate degree in naturopathic medicine from Bastyr University and a Master of Business Administration degree from Fairleigh Dickinson University, speaker and author of “Stop Stressing Me Out: 7 Solutions to Overcome Overwhelm & Conquer Disease Naturally" Caleb Maupin - Journalist and political analystGreg Palast - Investigative reporterJesse Ventura - Former professional wrestler, former governor of Minnesota, actor, political commentator, bestselling author, US Navy veteran and host of "The World According to Jesse" on RT America Dr. Clarence Lusane - Author, professor and activistDaniel Lazare - Investigative journalist and author of "The Velvet Coup"

Featured Interview: Outlook for the global population by 2100 -2100년까지의 전세계적 인구 추이 분석 Guest: Dr. Christopher Murray, Chair of Health Metrics Sciences and Director of the Institute for Health Metrics and Evaluation (IHME), University of Washington

Voter Resource: How to Cut Through The Politics of COVID-19 As a public health professional, I've been getting a lot of COVID-19 Questions: How do we go beyond the partisan political messaging to figure out when and how to reconnect with the world safely? What data should I believe? How do we know who to believe to keep ourselves and our families safe? How do I look at the data? How do I assess if my elected officials are doing a good job? In this video, I share two methods to look at the trends over time to know what's happening in your community: 1) Add up 15 days of data Add the new positive cases for the first 15 days of each month and divide that number by the total tests run over the same 15 days. Then compare that ratio over time. Is that ratio getting smaller? staying the same or getting bigger over time? 2) Look at Statewide Trends Statewide data is available through the University of Washington's Institute for Health Metrics and Evaluation (IHME.) It is an independent global health research center. https://covid19.healthdata.org/united-states-of-america Here you can easily look at the trends and predictions over time. What you want to see is the number of tests go up while the number of positive cases, hospitalizations, and deaths all trend down. Let me know if this was helpful and if you'd like to see more voter resources on the intersection of public health policy and politics to cut through the partisan rhetoric to learn what the data says and how partisan political messaging impacts public health. Connect with me on Twitter, Instagram, and LinkedIn @DemareeDVM

On June 10th, Greg Glassman stepped down from his position as CEO of CrossFit, and on this segment of Business Casual, Tyler Kern, Taylor Bagley, and Daniel Litwin opine on whether or not this move will be enough to ensure the future of the company as well as many of its affiliate gyms. Established in 2000 and characterized by high-intensity functional interval training and sound nutrition practices, CrossFit has been a highly popular health and fitness lifestyle solution that enables members to accomplish any goal—from improved health to weight loss to better performance. Boasting a network of more than 13,000 affiliates around the world with over 7,000 gyms offering the program in the US alone, it's estimated that there are roughly 4 million CrossFitters so devoted to this competitive approach to fitness that the community has often been described as cult-like. Well, Mr. Glassman's recent insensitive remarks regarding George Floyd as well as the COVID-19 pandemic on social media and via email may have driven a wedge in this close-‘fit' community, alienating members and gyms alike while outraging socially-oriented organizations like Black Lives Matter, medical-focused groups like the Institute for Health Metrics and Evaluation (IHME), and even the NFL. Litwin, Kern and Bagley chat about the many companies and brands that have crafted statements in support of the BLM movement and the fact that CrossFit remained silent during these weeks of nationwide protests and civil unrest, the racially and socially tactless tweets and emails between Glassman and the IHME and several of his affiliate gyms that sparked this national scandal, the proposed withdrawal of many gym affiliates from their contracts with the company, name brands like Reebok, FitAid and Rogue severing their partnerships with CrossFit, and the financial bind gyms are already facing due to pandemic social distancing and how Glassman's callous statements will further tip the fiscal scale for these workout locations as we move into the future. Tune into the Business Casual podcast each Wednesday and Friday to stay abreast of the recent trends and hottest topics impacting B2B and our world. And, be sure to check out MarketScale's industry pages for the latest thought leadership, news and event coverage.

This is an update to my earlier show to pull together what we know about the Coronavirus on this date, and what measures we can take. It focuses on the lack of solid information at this point and suggests a prudent course to stay safe. https://www.palain.com/health-topics/coronavirus-update-20200507/ https://www.palain.com/health-topics/scientific-and-medical-reports/ http://hackerpublicradio.org/eps.php?id=2685 https://www.cdc.gov/flu/about/burden/2017-2018.htm https://en.wikipedia.org/wiki/All_models_are_wrong http://www.healthdata.org/covid/updates https://www.medpagetoday.com/infectiousdisease/covid19/86127 https://www.cnn.com/2020/05/04/health/us-coronavirus-monday/index.html https://www.palain.com/health-topics/coronavirus-update-20200507/ Extracted from Palain.com under the tearms of Creative Commons Attribution-ShareAlike 4.0 International License. Coronavirus Update 20200507 The coronavirus pandemic is continuing throughout most of the world, and I wanted to put down some observations on where we stand today. First, note that I put the date in the title. This is because the situation in some ways changes day-by-day, even though there are continuities. That makes it a dangerous place to be because it is human nature to look for the latest news and jump on it if it looks good. And that is a prime mistake because we do not in fact know enough at this point to be confident in these news reports. I would refer you to my earlier essay, Scientific and Medical Reports, which is highly relevant right now. While I could not have predicted this pandemic when I wrote it, it contains basic principles that are always relevant. The nature of the press is that it is like the carnivorous plant in the movie Little Shop of Horrors, always crying "Feed Me!" And of course we are all interested if not to say anxious for any news on the course of this disease and where it is taking us. What this means is that you will see a unstoppable stream of news stories touting the latest study on one or another aspect of this. Add in the desire of politicians to spin things to their advantage, and you have a recipe for disaster. To keep sane, remember a few basic principles: One study proves nothing. There are lots of studies, and many of them are one-and-done without having any effect on medical practice. If there is an interesting result, it merely indicates an area for further study.Study results are only meaningful when they have withstood peer review and have been replicated by other scientists. This process does produce good results, but only with time. Only in movies do scientists go into the lab and come out 24 hours later with the answer.If you really want to know when all of this will end, there are only two answers. It can end very soon with an accompanying loss of life because the virus is still spreading. This is starting to show up in places that ignore the science. Going outside without a mask and carrying on as usual is not brave, it is stupid.The other answer is that a gradual relaxation of isolation can happen if it guided by sound science. Unfortunately, as just explained, that sound science is still being sought, and will take time.When you see the vast majority of doctors and scientists saying the same thing, that is your best assurance the information is accurate. Right now the number one priority is testing, testing, testing. So, with that background, do we know anything at this point? Yes, we do. But we also have a lot of unanswered questions. Second Wave? The first big question is whether there will be a second wave, and this is something that every qualified epidemiologist I have heard from says is guaranteed. And the reason is that a certain "fatigue" sets in with staying in isolation, and at least some people will convince themselves they don’t need to do it. They are wrong, and they will guarantee that second wave. In the 1918 Flu Pandemic, the second wave was far worse than the first wave. And don’t forget there was a third wave in that pandemic until it petered out in 1920. The best thing you can do is keep isolated if at all possible, and follow all of the guidelines: Wear a mask if you must go out, such as for groceries.Many stores are offering special hours for seniors. If you are one, take advantage.After a shopping trip, wash or disinfect items carefully. Remember that soap is all you need to defeat the virus, but use disinfectant wipes when soap is not practical.After returning, strip and place all of your clothes in the washer. The detergent should kill any virus that is there.Wash your hands with soap frequently.Try not to touch your face.Maintain at least two meters distance from anyone not in your household when you do go out.Try to stay fit. I go for walks in my neighborhood if there aren’t too many others out, and when there is someone else out, I give them a wide separation. I also do gardening in my own yard, and exercise in my home. That won’t prevent you from getting the disease, but it may prevent you from dying of it. Yeah, this is all of the stuff we have been hearing all along. But annoying as it is, it does work if you do it. Is the virus mutating? Yes. In other news, water is wet. Face it, mutation is what organisms do, and that has been true for billions of years. The question you really have is "Is it getting worse?" And right now the answer is "We don’t know." Sorry I can’t give you any more determinative answer, but we are only at the "one study" phase right now, and we are a ways off from the "peer-reviewed, replicated consensus" phase that will resolve this. There are indications that at least this virus does not mutate as much as influenza, but even that may require more study. Am I Immune? We would all love to know if we are immune. This requires two big things to give a good answer. First, does having the disease and then recovering give you immunity? And the sad truth is that we don’t know yet. The common cold is a coronavirus, and you never get immunity. Influenza is a virus, and getting it one year provides no immunity the next. And if getting it once does provide immunity, we still need testing to discover this. The number one priority right now in all locations should be testing, testing, testing. That is the prerequisite for doing any decent epidemiology. There was a report (note: one study) out of South Korea that indicated that some people could get the disease twice, but they re-analyzed the data and decided that it might have been false positives. That is the kind of thing that happens when scientists are trying to do a year’s worth of work in few weeks, which is what they are doing. Is It More Infectious Than We Thought? Again, very unclear. And even less clear is what this implies. An argument is being made that if the rate of infection is higher, given the number of deaths, that would imply it is less lethal. And that is being used to argue in favor of this not being a big deal, so reopen everything. But to put it in perspective, in the 2017-2018 flu season, which was on the high end of deaths, we had 61 thousand deaths in the U.S. Today, in just over 2 months, we have 75 thousand deaths in the US, and that is with all of the extraordinary measures we put in place to keep people safe. To make an argument that Covid-19 is no more dangerous than the flu is to be criminally stupid at best. Didn’t They Predict More Deaths? Why yes, they did. A widely used model in the US is from the Institute for Health Metrics and Evaluation (IHME), at the University of Washington. And they have issued forecasts that ranged from hundreds of thousands of deaths to around 60,000 deaths. Clearly they have no idea what they are doing, right? Not so fast. As the statistician George Box famously said, "All models are wrong but some are useful". In this case you have to factor in two things. One is uncertainty, of course. To forecast how many people will die, it helps to know how many people have died, and this has been subject to fierce debate. And here it gets difficult, since one argument is over what counts as a Covid-19 death. And since every one of our 50 states has their own health reporting system, there is a wide disparity. One example of this is the idea of "excess deaths". If a given area has a pretty regular death rate for a number of years, and suddenly that death rate jumps 500% in the midst of a pandemic, it is reasonable to suspect those "excess deaths" are a result of the coronavirus. But if those deaths get counted, others will argue that it is inflating the numbers, and that only a positive coronavirus serum test should count. Since each state does this differently, this leads to the odd result that the disease appears more or less lethal depending on your state of residence. And that means politicians have incentive to get the numbers they want. The other factor complicating things is the phenomenon known as the "self-preventing" prophecy. You see, the initial high estimates tended to be "This is what will happen if you don’t take strong measures", and of course they were very high. And we know that governments like the UK and the US looked at those predictions, and started to take some stronger measures. So after a little bit, new predictions came out that were lower as a result of those measures. And now we are seeing misguided efforts to get people to go out and resume normal life, and as a result the newest forecasts are going up again. This is a feedback loop, in other words.

Most of Minnesota’s stay-at-home order expires on Monday – even as COVID-19 cases and deaths continue to mount. Gov. Tim Walz says models produced by the University of Minnesota showed only small benefits to extending the stay-at-home directive into early June. But many public health leaders – including Dr. Anthony Fauci – warn that opening too fast or too broadly could trigger a second and larger wave of COVID-19 infections this summer. Mondays on MPR News with Kerri Miller, we tackle the latest science and public health policy about the pandemic. This week: What do the various models project could happen this summer? And how can the public be both safe and smart as we emerge from a two-month period of isolation? COVID-19 ethics How do we decide? May 11 An infectious disease doctor and surgeon weigh in on COVID-19 policy Guests: Dr. Nahid Bhadelia, associate professor of medicine at Boston University School of Medicine and an infectious disease physician at Boston Medical Center Dr. Theo Vos, epidemiologist and professor at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington To listen to the full conversation you can use the audio player above.  Subscribe to the MPR News with Kerri Miller podcast on: Apple Podcasts, Google Podcasts , Spotify or RSS

Our Microsoft for Health panel looks forward to the future of healthcare. As healthcare responds to the current COVID-19 crisis, it is accelerating its adoption of technologies that would have taken years to implement before the current need for change.The panel discusses how Artificial Intelligence and Machine Learning is impacting healthcare today and in the future. Hear how Microsoft's AI/ML technologies and the Azure cloud are being brought to bear to empower people to work differently.Not only are these technologies helping the current situation, but partners are providing the next generation of medicine today. Learn how Healthcare will be forever changed by the technology solutions currently being introduced today.TranscriptShow NotesMicrosoft for HealthcareMicrosoft Industry Health BlogMicrosoft 365 and healthcareMicrosoft for Healthcare on LinkedInMicrosoft’s Covid-19 ResponsePatient outreach & triage (Healthcare bot, PlasmaBot)Track allocation of resources & supplies - Protecting People EverywhereCommunication for crisis managementDeliver & manage continuous care (Virtual Visits)Dissemination of accurate information (COVID Open Research Dataset (CORD19), Contact Tracing)Supporting your healthcare organization and community during crisesComplimentary 6-month Office 365 E1 to help connect employees during COVID-19 responseEnabling the NHS to continue delivering frontline healthcareGE Healthcare is extending its longtime collaboration with Microsoft to launch a cloud-based COVID-19 patient monitoring software for health systemsLearn about Microsoft’s Healthcare Bot service that uses artificial intelligence (AI) to help respond to patient inquiriesBuild a crisis management site to connect people and informationUse this preconfigured template to rapidly share information across facilities and collect employee updates with Power Apps Crisis Management templateQuickly optimize Office 365 traffic for remote staff and reduce the load on your infrastructure Balancing cloud services continuity for crucial health and safety organizationsWork remotely, stay secure—tips for CISOsArtificial Intelligence in HealthcareUses of AI for health include the work to fight COVID-19 is already underway. A handful of key partnerships include the following.The  COVID-19 High Performance Computing Consortium, a private-public effort spearheaded by the White House Office of Science and Technology Policy, for which Microsoft is providing researchers access to the world’s most powerful computing resources, which can significantly speed the pace of scientific discovery in the fight to stop the virus. Around the world, Microsoft’s research scientists, spanning computer science, biology, medicine and public health, are collaborating on projects in the consortiumThe Institute for Health Metrics and Evaluation (IHME), a global health research organization at the University of Washington School of Medicine, is releasing a set of COVID-19 data visualizations and forecasts that the White House, FEMA, governors and hospital administrators have started using to mobilize resourcesThe Washington State Department of Health is working on a new dashboard that aims to increase timeliness, accuracy and speed of data reporting to the public. The dashboard relies on data reported by local health jurisdictions, healthcare facilities and labsFolding@home, a global organization that uses distributed computing is researching COVID-19 proteins that could help with designing therapeuticsThe Sepsis Center of Research Excellence (SCORE-UW), part of the University of Washington’s Department of Medicine, is a global collaboration between a network of hospitals, industry, blood banks, universities and funding partners. Using clinical data, radiologic imaging and other patient biomarker responses, SCORE-UW is developing novel algorithms to predict, and improve, healthcare and socioeconomic outcomes of COVID-19 positive patientsTake, the Brazilian leader in chatbots and the smart contacts market, developed a bot to bring official and credible information to the public and connect potential patients to medical teams to avoid overloading Brazilian hospitalsGuestsGareth HallSenior Director - Microsoft WorldWide Health SolutionsGareth leads the team driving the worldwide solutions strategy for the Microsoft Health business, focused on working with Microsoft product teams and partners to build solutions on the Microsoft cloud platforms (Azure, Dynamics 365 and Office 365).LinkedInJohn DoyleDirector, Cloud & AI, Microsoft HealthcareAs a Director within the worldwide commercial business industry team at Microsoft, John Doyle is responsible for the development of business strategy and partnerships across the healthcare industry, globally. John, engages with industry customers and partners, developing strategies and repeatable technology solutions that harness the power of cloud and AI to drive innovation and industry transformation.LinkedInDavid HouldingDavid is the Director of Healthcare experiences on Microsoft Industry Experiences team. He has extensive experience in working with partners for healthcare in applicable technologies, most lately the cloud, blockchain, and AI.LinkedInTwitter

Microsoft for Healthcare is working hard to help healthcare throughout the COVID-19 crisis and to plan for what comes after the pandemic. Our guests discuss how Microsoft is responding to the current COVID-19 crisis as well as their mission in healthcare and the future of the industry.Our guests describe how they work with partners to find the right capabilities enabled by Microsoft solutions. Additionally, we discuss several Microsoft healthcare-focused products in use today. Learn how Microsoft technologies are being used to solve real world problems related not only to the current pandemic, but other important healthcare problems.The panel discusses the partnerships occurring between competitors to combat COVID-19. Learn about Microsoft partner solutions available to help "flatten the curve" during this crisis.TranscriptShow NotesMicrosoft for HealthcareMicrosoft Industry Health BlogMicrosoft 365 and healthcareMicrosoft for Healthcare on LinkedIn Microsoft’s Covid-19 ResponsePatient outreach & triage (Healthcare bot, PlasmaBot)Track allocation of resources & supplies - Protecting People EverywhereCommunication for crisis managementDeliver & manage continuous care (Virtual Visits)Dissemination of accurate information (COVID Open Research Dataset (CORD19), Contact Tracing)Supporting your healthcare organization and community during crisesComplimentary 6-month Office 365 E1 to help connect employees during COVID-19 responseEnabling the NHS to continue delivering frontline healthcareGE Healthcare is extending its longtime collaboration with Microsoft to launch a cloud-based COVID-19 patient monitoring software for health systemsLearn about Microsoft’s Healthcare Bot service that uses artificial intelligence (AI) to help respond to patient inquiriesBuild a crisis management site to connect people and informationUse this preconfigured template to rapidly share information across facilities and collect employee updates with Power Apps Crisis Management templateQuickly optimize Office 365 traffic for remote staff and reduce the load on your infrastructure Balancing cloud services continuity for crucial health and safety organizationsWork remotely, stay secure—tips for CISOs Artificial Intelligence in HealthcareUses of AI for health include the work to fight COVID-19 is already underway. A handful of key partnerships include the following.The  COVID-19 High Performance Computing Consortium, a private-public effort spearheaded by the White House Office of Science and Technology Policy, for which Microsoft is providing researchers access to the world’s most powerful computing resources, which can significantly speed the pace of scientific discovery in the fight to stop the virus. Around the world, Microsoft’s research scientists, spanning computer science, biology, medicine and public health, are collaborating on projects in the consortiumThe Institute for Health Metrics and Evaluation (IHME), a global health research organization at the University of Washington School of Medicine, is releasing a set of COVID-19 data visualizations and forecasts that the White House, FEMA, governors and hospital administrators have started using to mobilize resourcesThe Washington State Department of Health is working on a new dashboard that aims to increase timeliness, accuracy and speed of data reporting to the public. The dashboard relies on data reported by local health jurisdictions, healthcare facilities and labsFolding@home, a global organization that uses distributed computing is researching COVID-19 proteins that could help with designing therapeuticsThe Sepsis Center of Research Excellence (SCORE-UW), part of the University of Washington’s Department of Medicine, is a global collaboration between a network of hospitals, industry, blood banks, universities and funding partners. Using clinical data, radiologic imaging and other patient biomarker responses, SCORE-UW is developing novel algorithms to predict, and improve, healthcare and socioeconomic outcomes of COVID-19 positive patientsTake, the Brazilian leader in chatbots and the smart contacts market, developed a bot to bring official and credible information to the public and connect potential patients to medical teams to avoid overloading Brazilian hospitalsGuestsGareth HallSenior Director - Microsoft WorldWide Health SolutionsGareth leads the team driving the worldwide solutions strategy for the Microsoft Health business, focused on working with Microsoft product teams and partners to build solutions on the Microsoft cloud platforms (Azure, Dynamics 365 and Office 365).LinkedInJohn DoyleDirector, Cloud & AI, Microsoft HealthcareAs a Director within the worldwide commercial business industry team at Microsoft, John Doyle is responsible for the development of business strategy and partnerships across the healthcare industry, globally. John, engages with industry customers and partners, developing strategies and repeatable technology solutions that harness the power of cloud and AI to drive innovation and industry transformation.LinkedInDavid HouldingDavid is the Director of Healthcare experiences on Microsoft Industry Experiences team. He has extensive experience in working with partners for healthcare in applicable technologies, most lately the cloud, blockchain, and AI.LinkedInTwitter

Quotes:“If we try to rush to get our lives back to normal, the number of cases will spike higher and earlier. And we can’t afford that.” - Governor Ralph Northam, April 13, 2020“The scenario that we don’t want is for Virginia to do one thing and for Maryland to do another as far as when restaurants or bars would open. We’re only separated by the Potomac River and that’s the case with DC as well. We also have North Carolina to our south and so we are working very closely.” - Governor Ralph Northam, April 13, 2020“A lot of what makes African-Americans susceptible to COVID disease are issues that pre-existed the arrival of COVID. Increased rates of hypertension, diabetes, strokes, heart attacks, kidney disease. These are things that are linked to the structural barriers and racism, institutions that were set up a while ago, but persist nevertheless. This is an instance where we can draw a direct line between the health and safety of one community and the health and safety of another community.” - Dr. Taison Bell, April 13, 2020“There is absolutely no way that we can cut five to ten percent of the department’s operating budget and not see some effect on services that we provide to our community every day.” - Albemarle County Executive Jeffrey Richardson, April 13, 2020Resources:Institute for Health Metrics and Evaluation (IHME) model CHIME Model News release on UVA Biocomplexity Institute ModelPiedmont Environmental Council’s events page for information on April 16 Mobility and Connectivity Webinar 

Coronavirus has killed 20,460 people in the United States, just higher than number of deaths in Italy. Since New York's first recorded death on March 14, more than 6,500 of its people have died of COVID-19 and more victims have died in New York than in any country aside France, Spain and Italy.Infectious diseases expert Dr. Anthony Fauci said Friday morning (April 10) that in about a week an antibody test would become available to show who has already been infected with the novel coronavirus, The New York Times reported.As the virus's spread started to increase in the United States, a team at the University of Washington in Seattle used the daily death rates in a model to speculate the number of beds and ventilators that US hospitals would need. “Our modeling approach is based off the deaths — that is the core part that tells us about the epidemic,” says Theo Vos, an epidemiologist at the Institute for Health Metrics and Evaluation (IHME) at the university. IHME's projections were reportedly among those used by US President Donald Trump's administration in late March.

Good news is bad news for the New York Times, CBS, CNBC, USA Today, & the Washington Post. They just love publishing terrifying and dire predictions based on days-old model projections and refuse to tell us how much better we’re doing than it appeared two weeks ago. What explains their irrational love affair with bad news? No American hospital has yet needed a ventilator that they lack. There is a troubling reason for why the American Center for Disease Control (CDC) directs doctors and hospitals to list cause of death as COVID-19 even in the absence of any test or other evidence. Do you agree with Toyota’s 5 business principles, and Panasonic’s 7, and General Electric’s 8. How the Passover Seder https://rabbidaniellapin.com/product/seder-set/ can instill ambition in participants of every background. ...... Website referenced: Institute for Health Metrics and Evaluation (IHME)  https://covid19.healthdata.org/

When a building serves a unique mission to improve global health and environmental resilience, sustainable design becomes more than a talking point. The Population Health Building at the University of Washington was largely funded by a grant from the Bill and Melinda Gates Foundation and reflects the foundation’s desire to help all people lead healthy and productive lives by combating extreme hunger and poverty around the globe. A unique global mission demands a unique building. Kristen Dotson is at the center of the action bringing almost two decades of experience in sustainable projects to the team of stakeholders. Dotson is an architect and director of sustainability with the Miller Hull Partnership in downtown Seattle. Even the firm’s offices speak to their specialty design practice. “Miller Hull has an incredible company culture and we wanted to hold ourselves to the same standard that we try to push our clients toward. So we decided to pursue the living building challenge as part of our office renovation,” said Dotson. “We really wanted to leverage the knowledge we have of red list compliant building materials to make the healthiest environment we could and also take advantage of all the daylight since we overlook the Puget Sound. No one has a private office and all of our partners are scattered among the projects that they're working on.” Like the Miller Hull offices, the Population Health Building reflects the values of its funders, designers and tenants; all stakeholders have worked collaboratively on the design. It brings together faculty, researchers and students from the School of Public Health, the Department of Global Health and the Institute for Health Metrics and Evaluation (IHME). “Putting them all under one roof is designed to see how researchers can collaborate to find population health solutions further and faster, using data visualization and data tracking metrics,” said Dotson. This approach aligns with the work of the Gate’s foundation, which supports IHME’s work in developing tools like the global burden of disease database which in turn enables policy makers to make better decisions and investments in helping people live longer, healthier lives. A lot of time went into design on the front end to save time and money on the back end. “We pulled together as a team to really understand their goals, understanding what they were trying to achieve, not just what the program said, but infusing that mission in every aspect of the building,” said Dotson. “For this particular project, the word health is on the building. So if we're not addressing health at every scale in this project, if we're not at least thinking about it, then we should.” When you look at the building’s plans, something is clearly missing from most of the floors of the project, that is corridors and hallways. That missing element is intentional, it’s not like they forgot to include them or ran out of money and needed to cut costs. According to Dotson, corridors eat up space and kill collaboration, particularly if corridors lead to private offices. “We want collaboration between these three tenants. We want them to talk to each other. We want them to run into somebody they haven't seen for a while and say, ‘What are you working on?’ Every square foot is trying to build a space where people can linger and socialize in a way that builds their community, but also builds the intellectual capital of the work there.” Next fall, the Population Health building will open to faculty, researchers and students.

In this episode of Take as Directed, Steve Morrison speaks with Dr. Christopher Murray, Director of the Institute for Health Metrics and Evaluation (IHME) of the University of Washington. Dr. Murray walks through IHME’s ongoing Global Burden of Disease analysis, as he and his team have been evaluating eating habits and food systems for people in 195 countries. Dr. Murray shares the study’s most important—and surprising—findings about global diet-related issues.

In this episode of Take as Directed, Steve Morrison speaks with Dr. Christopher Murray, Director of the Institute for Health Metrics and Evaluation (IHME) of the University of Washington. Dr. Murray walks through IHME’s ongoing Global Burden of Disease analysis, as he and his team have been evaluating eating habits and food systems for people in 195 countries. Dr. Murray shares the study’s most important—and surprising—findings about global diet-related issues.

Christopher Murray, director of the Institute for Health Metrics and Evaluation (IHME), is a pioneer in the world of global burden of disease measurement. In April, IHME released their annual report on global health financing and two accompanying articles in The Lancet. Chris joins us for today’s episode to discuss the future of financing the global HIV/AIDS pandemic and the efforts to move towards universal health coverage around the world.   Hosted by Steve Morrison. Produced by Alex Bush. Edited by Ribka Gemilangsari.

Who's doing a great job of collecting health data and translating it into engaging public health multimedia? For many in global health, the clear leader is the Institute of Health Metrics and Evaluation (IHME) at the University of Washington in Seattle. Indeed, on my first day at work at IVAC, everyone was throwing around the IHME acronym around like it was PBnJ and definitely a lol moment if you didn't know what it stood for. Our latest podcast features Bill Heisel, Director of Global Engagement at IHME and a must know for all public health lovers. Check out our show links at www.publichealthunited.org and follow us on Twitter, Instagram and Facebook at PHUpodcast.

Thanks to http://www.givewell.org/ for sponsoring this video! To learn more about the Against Malaria Foundation, visit: http://www.givewell.org/AMF or https://www.againstmalaria.com. Thanks also to our supporters on https://www.patreon.com/MinuteEarth ___________________________________________ FYI: We try to leave jargon out of our videos, but if you want to learn more about this topic, here are some keywords to get your googling started: Malaria - a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. Parasite - an organism that benefits by living in/on a host organism and deriving nutrients at the host's expense. Host - an organism in/on which another organism lives. Protozoa - a group of single-celled microscopic animals (not bacteria or viruses) that includes the Plasmodium species. Plasmodium - a genus of parasitic protozoa, many of which cause malaria in their hosts. Four species regularly infect humans: P. falciparum, P. vivax, P. malariae, & P. ovale. P. falciparum - the Plasmodium species that kills the most people, by causing malignant malaria, the most dangerous form of malaria. Anopheles gambiae - a ‘complex' of at least seven species of mosquitoes that are the main vectors of P. falciparum in sub-Saharan Africa. Species complex - a group of closely related species that look so similar that the boundaries between them are often unclear. Hunting and gathering - depending primarily on wild foods for subsistence Paleontology - the study of fossils and what fossils tell us about the past, about evolution, and about how humans fit into the world. ___________________________________________ Credits (and Twitter handles): Script Writer: Alex Reich (@alexhreich) Script Editor: Emily Elert (@eelert) Video Illustrator: Qingyang Chen Video Director: Emily Elert (@eelert) Video Narrator: Kate Yoshida (@KateYoshida) With Contributions From: Henry Reich, Ever Salazar, Peter Reich, David Goldenberg Music by: Nathaniel Schroeder: http://www.soundcloud.com/drschroeder _________________________________________ Like our videos? Subscribe to MinuteEarth on YouTube: http://goo.gl/EpIDGd Support us on Patreon: https://goo.gl/ZVgLQZ Also, say hello on: Facebook: http://goo.gl/FpAvo6 Twitter: http://goo.gl/Y1aWVC And find us on itunes: https://goo.gl/sfwS6n ___________________________________________ If you liked this week’s video, we think you might also like: Amazing animation of seasonal temperature suitability for malaria https://goo.gl/63pYGt Americapox CGPGrey video https://www.youtube.com/watch?v=JEYh5WACqEk The History of Malaria, an Ancient Disease http://www.cdc.gov/malaria/about/history/ ___________________________________________ References: Carter, R., & Mendis, K. N. (2002). Evolutionary and historical aspects of the burden of malaria. Clinical microbiology reviews, 15(4), 564-594. http://cmr.asm.org/content/15/4/564.full Gething, P. W., et al. (2011). A new world malaria map: Plasmodium falciparum endemicity in 2010. Malaria journal, 10(1), 1. http://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-10-378 Gething, P. W., et al. (2011). Modelling the global constraints of temperature on transmission of Plasmodium falciparum and P. vivax. Parasites & Vectors, 4(1), 1. http://parasitesandvectors.biomedcentral.com/articles/10.1186/1756-3305-4-92 Hay, S. I., et al. (2004). The global distribution and population at risk of malaria: past, present, and future. The Lancet infectious diseases, 4(6), 327-336. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145123/ Institute for Health Metrics and Evaluation (IHME). (2016). GBD Compare Data Visualization. Seattle, WA: IHME, University of Washington. Retrieved from http://vizhub.healthdata.org/gbd-compare. Liu, W., et al. (2010). Origin of the human malaria parasite Plasmodium falciparum in gorillas. Nature, 467(7314), 420-425. doi: 10.1038/nature09442 Malaria: Fact sheet (April 2016). Retrieved from http://www.who.int/mediacentre/factsheets/fs094/en/ Packard, R. M. (2007). The making of a tropical disease: a short history of malaria (pp. 1-66 ). Baltimore. Rich, S. M., et al. (2009). The origin of malignant malaria. Proceedings of the National Academy of Sciences, 106(35), 14902-14907. doi: 10.1073/pnas.0907740106 Shah, S. (2010). The Fever: how malaria has ruled humankind for 500,000 years (pp. 1-33). Macmillan. Sundararaman, S. A., et al. (2016). Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria. Nature communications, 7. DOI: 10.1038/ncomms11078 Webb, J. L. (2009). Humanity's burden: a global history of malaria (pp. 1-91). Cambridge: Cambridge University Press. World Health Organization. (2015). World malaria report 2015. World Health Organization. Retrieved from http://www.who.int/malaria/publications/world-malaria-report-2015/report/en/

William Heisel is the Director of Global Engagement at the Institute for Health Metrics and Evaluation (IHME). In this role, Heisel is responsible for IHME's media relations, digital outreach, events and marketing, publications, scientific communications, and external relations, including government engagements and policy translation. He also is leading IHME's internal community-building initiatives and manages the organization's advancement efforts. As Director of Global Engagement, Heisel oversees the publication of Population Health Metrics, the scientific journal administratively housed at IHME, and advises on the Institute's publication strategy. He and IHME's Chief Strategy and Operations Officer oversee communications and coordination with the growing Global Burden of Disease collaborative network, currently at more than 1,000 researchers in more than 100 countries. In addition, his team administers the Roux Prize, one of global health's highest honors. Heisel, who joined IHME in 2009, has a BA in Journalism and Spanish from the University of Montana. Prior to joining the Institute, he was a reporter at the Los Angeles Times. IHME was established at the University of Washington in Seattle in 2007. Its mission is to improve health through better health evidence. 00:00 Bill explains what he does as the Director of Global Engagement at the Institute for Health Metrics and Evaluation (IHME).02:50 Why insurers are particularly interested in IHME's work.05:00 Cost benefits vs. population health.07:00 The why and how behind breaking the burden of disease.10:45 What insurers can do with the information that IHME collects.13:00 The difference in quantifying population health.13:20 “Everyone can only die once.”16:00 Factoring in co-morbidities.18:30 True causes of death falling into the cracks of official statistics.22:30 Delivering data in a low-cost and efficient way is just as important at gathering the data.23:15 Bill's prediction for the future of healthcare in the US.26:00 IHME's consideration of social determinants.29:00 You can find out more at healthdata.org.

Dr. Christopher Murray is Director of the Institute for Health Metrics and Evaluation (IHME), a groundbreaking research organization that compiles global health data on a revolutionary scale. Dr. Murray discusses global obesity, China as a microcosm of the world and how far the developing world's health care lags behind ours.