Podcast appearances and mentions of Michael F Holick

Vitamin D is more than a vitamin—it's a hormone that influences everything from your immune system to cardiovascular health, cognition, and longevity. In this conversation, Dr. Michael Holick breaks down the science of vitamin D synthesis, the truth about sun exposure vs. supplements, and why vitamin D deficiency is far more common—and more dangerous—than most people realize. You'll learn how skin pigmentation, UVB exposure, and supplementation protocols impact your vitamin D levels, and why D3 is more effective than D2. Dr. Holick also dives into mood, cognition, and the controversial role of vitamin D in chronic disease and COVID outcomes. With dosage guidelines by age and weight, plus practical advice on avoiding vitamin D toxicity, this episode is a masterclass on one of the most important—yet misunderstood—nutrients in health and longevity. Learn more about Dr. Michael F. Holick: https://drmichaelholick.org/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-410 Overview: In this episode, we discuss the latest updates on vitamin D. Learn about its link to common disorders, when to consider supplementation, and what the most recent practice guideline says about vitamin D and disease prevention—empowering you to make informed decisions and improve patient care without unnecessary screenings or treatments. Episode resource links: Marie B Demay, Anastassios G Pittas, Daniel D Bikle, Dima L Diab, Mairead E Kiely, Marise Lazaretti-Castro, Paul Lips, Deborah M Mitchell, M Hassan Murad, Shelley Powers, Sudhaker D Rao, Robert Scragg, John A Tayek, Amy M Valent, Judith M E Walsh, Christopher R McCartney, Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline, The Journal of Clinical Endocrinology & Metabolism, Volume 109, Issue 8, August 2024, Pages 1907–1947, https://doi.org/10.1210/clinem/dgae290 Michael F. Holick, Neil C. Binkley, Heike A. Bischoff-Ferrari, Catherine M. Gordon, David A. Hanley, Robert P. Heaney, M. Hassan Murad, Connie M. Weaver, Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline, The Journal of Clinical Endocrinology & Metabolism, Volume 96, Issue 7, 1 July 2011, Pages 1911–1930, https://doi.org/10.1210/jc.2011-0385 Guest: Jillian Joseph, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  

Was man teilweise über Vitamin D hört, klingt fast zu schön, um wahr zu sein. Andererseits deuten hunderte verschiedener Forschungsarbeiten darauf hin, dass Vitamin D zur Vorbeugung einer Reihe von Krankheiten beitragen kann – darunter Osteoporose, Depression, Autoimmun- und Herz-Kreislauf-Erkrankungen. Ärzte empfehlen es. Gesundheits- und Fitnesspodcaster sprechen darüber. Vielleicht geht Dir sogar Deine Lieblingstante damit auf die Nerven. Bei all dem Hype ist die Frage berechtigt: "Solltest Du Vitamin D einnehmen?" Hier sind die Antworten – und die neuesten Fakten über ein faszinierendes Vitamin, das ein wahrer Verwandlungskünstler ist. ____________ *WERBUNG: KoRoDrogerie.de: 5% Ermäßigung auf alles mit dem Code „FMM“ beim Checkout. ____________ Ressourcen zur Folge: Literatur: Ratgeber Nahrungsergänzung – Mark Maslow (kostenlos auf MarathonFitness) Blut: Die Geheimnisse unseres flüssigen Organs* – Ulrich Strunz (Heyne) Vitamin D* – Uwe Gröber, Michael F. Holick (Wissenschaftl. Verlagsgesellschaft) Blutuntersuchung (Selbsttest): Vitamin D Test* von Medivere Präparate: D-Form 2.000 K2+* von FormMed D-Form 2.000 K2+ vegan* von FormMed ____________

Dr Michael Holick is a pioneer in vitamin D science and has spent a lifetime researching and exploring what he believes are its potentially life-changing benefits. He argues that across the world guidelines for the amount of vitamin D we need are simply too low. And that many of us, even those  living in a hot climate, will not be able to get enough vitamin D from sunlight alone. Dr Horlick contends that not only do we need vitamin D for bone health, we also need it for many other critical functions too. Without a sufficient amount, he says our immune system can't operate effectively, and that a deficiency of the vitamin is linked to a wide range of other health conditions from heart disease and depression, to auto-immune illnesses and cancer. In this interview, Michael discusses why he believes vitamin D is so essential and reveals the levels he thinks we all need take for optimal health.   Dr Michael F. Holick is a Professor of Medicine, Physiology and Biophysics. He is Director of the General Clinical Research Unit;  Director of the Bone Health Care Clinic and the Director of the Heliotherapy, Light, and Skin Research Center at Boston University Medical Center. You can sign up to the mailing list to the podcast and be first to know when a new episode is published at https://www.whatyourgpdoesnttellyou.com and also find out more about the pod there. The host of the podcast, Liz Tucker is an award winning medical journalist and former BBC producer and director.  You can follow Liz on Twitter at https://twitter.com/lizctucker and read her Substack newsletter about the podcast at https://liztucker.substack.com If you would like to support this podcast you can do so at patreon.com/whatyourgpdoesnttellyou or via PayPal at https://www.patreon.com/WhatYourGPDoesntTellYou What Your GP Doesn't Tell You has been selected by Feedspot as one of the top 20 UK Medical Podcasts https://blog.feedspot.com/uk_medical_podcasts/  

video: https://app.air.inc/a/cW1vAB3wp?ts=0 The Dark Truth of America's Federation Of State Medical Boards (start @ 3:44) Black gold? Rhizome extract said to have anti-ageing and anti-diabetic effects Oryza Chemical (Thailand), Black ginger extract could have important implications for healthy ageing and diabetes, as well as athletic performance. Presented in Bangkok by Oryza Oil & Fat Chemical's Masami Kawaziri, the herbaceous plant is also called black turmeric in Japan, and krachai dum in its country of origin, Thailand. The plant's extract has been used in Thailand for many years as a traditional medicine to boost energy and relieve gastrointestinal problems, and more recently, researchers in Asia have been looking into its benefits for seniors, diabetics and sportspersons. Energising results Its polymethoxyflavones are said to enhance energy production, thereby improving glucose, fat and lipid metabolism. This can either prevent metabolic syndrome, or aid in treating diabetes. The boost in energy production also helps to enhance athletic performance and recovery. Kawaziri shared the results of a 2016 study on the effects of black ginger extract intake on physical strength, skin condition, post-exercise fatigue, and general fatigue. Subjects who had been given the extract reported an increase in strength, and being less fatigued overall and after exercise. Brains and brawn Kawaziri said this was important for the elderly as well, since the extract is believed to minimise muscle loss. He added that the extract could play a part in “preventing poor blood circulation” and lowering blood pressure. Furthermore, he said the extract could help to enhance and maintain cognitive function, delaying or perhaps even preventing diseases like Alzheimer's. Higher levels of fluoride in pregnant woman linked to lower intelligence in their children University of Toronto Fluoride in the urine of pregnant women shows a correlation with lower measures of intelligence in their children, according to University of Toronto researchers who conducted the first study of its kind and size to examine fluoride exposure and multiple states of neurodevelopment. “Our study shows that the growing fetal nervous system may be adversely affected by higher levels of fluoride exposure,” said Dr. Howard Hu, the study's principal investigator and professor of environmental health, epidemiology and global health at the Dalla Lana School of Public Health. “It also suggests that the prenatal nervous system may be more sensitive to fluoride compared to that of school-aged children.” Tap water and dental products have been fluoridated in communities in Canada and the United States (as well as milk and table salt in some other countries) by varying amounts for more than 60 years to prevent cavities and improve bone health. In recent years, fierce debate over the safety of water fluoridation – particularly for children's developing brains – has fuelled researchers to explore the issue and provide evidence to inform national drinking water standards. There are some known side effects of fluoride. For example, dental defects like mild staining are common among those ingesting recommended levels of fluoride in the United States and Canada. Skeletal fluorosis – excessive accumulation of fluoride in the bones – is much less common and only observed at levels of fluoride in the water that are more than five to 10 times higher than those recommended. “Relatively little is known, with confidence, about fluoride's impact on neurodevelopment,” said Hu, whose research team included experts from U of T, National Institute of Public Health of Mexico, University of Michigan, McGill University, Indiana University, Mount Sinai School of Medicine and Harvard School of Public Health. The study, “Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 6-12 Years of Age in Mexico,” published today in Environmental Health Perspectives, analyzed data from 287 mother-child pairs in Mexico City that were part of the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) project, which recruited pregnant women from 1994 to 2005 and has continued to follow the women and their children ever since. The research team analyzed urine samples that had been taken from mothers during pregnancy and from their children between six and 12 years of age to reconstruct personal measures of fluoride exposure for both mother and child. “This is significant because previous studies estimated exposures based on neighbourhood measurements of drinking water fluoride levels, which are indirect and much less precise measures of exposure. They also looked at children's exposures instead of prenatal exposures or had much smaller sample sizes of subjects to study,” said Dr. Hu. The researchers then analyzed how levels of fluoride in urine related to the children's verbal, perceptual-performance, quantitative, memory, and motor abilities at age four and once more between the ages of six and 12. Analyses were adjusted for other factors known to impact neurodevelopment, such as gestational age at birth, birthweight, birth order, sex, maternal marital status, smoking history, age at delivery, IQ, education, socioeconomic status and lead exposure. With regard to the study's implications for populations in North America, researchers found that urinary fluoride levels in pregnant women were somewhat higher than, but within the general range of, urinary fluoride levels seen in non-pregnant general populations in Canada and the United States. However, in Dr. Hu's opinion, the findings do not provide enough information to suggest there is no safe level of fluoride exposure. “The potential risks associated with fluoride should be further studied, particularly among vulnerable populations such as pregnant women and children, and more research on fluoride's impact on the developing brain is clearly needed.” Polyphenol blend may boost post-exercise recovery: RCT University of Murcia (Spain), and the University of Montpellier (France) Daily supplementation with a blend of extracts from mangosteen, elderberry, and pomegranate may delay muscle soreness and help manage post-exercise recovery, says a new study. Consumption of Fytexia's polyphenol-rich ingredient branded TensLess was associated with a 28% reduction in the perception of delayed onset muscle soreness (DOMS), compared with a placebo group, according to results of a randomized, placebo-controlled, crossover study. Biomarkers of muscle damage were also reduced, in correlation with the decreases in DOMS, reported scientists from Fytexia (France), Catholic University of Murcia (Spain), and the University of Montpellier (France) in the journal Phytotherapy Research . “This prospective study highlights the beneficial, both acute and sub-chronic effects of the supplementation with TensLess, a polyphenol-rich extract-based food supplement, on adverse symptoms associated with DOMS, namely eccentric exercise-related markers of muscle impairment,” they wrote. Study details The researchers recruited 13 recreationally active athletes (men and women) to participate in their study. Participants were randomly assigned to consume placebo or 1.5 grams per day of TensLess, composed of polyphenol-rich extracts from mangosteen (Garcinia mangostana L.), pomegranate (Punica granatum L.), and black elderberry (Sambucus nigra L.) combination for five days. All of the study participants performed an eccentric exercise protocol on day one of the study, and DOMS and biomarkers of muscle damage were monitored for four more days. This was then followed by a three-week “washout” period before they were crossed over to the other group for five more days. The results showed that TensLess supplementation provided a significant 33% decrease in DOMS perception as early as the first 24 hours following physical exercise, compared to placebo. In addition to this acute benefit, a 28% reduction in DOMS perception was reported compared to the placebo group for the full duration of the study. These effects were correlated with a lower levels of muscle damage-associated biomarkers, specifically creatine kinase, creatinine and myoglobin during the 4 days post-workout, added the researchers. Taken together, these positive results clearly indicate that post-exercise supplementation with TensLess may preserve myocytes and reduce soreness following eccentric exercise-induced damages, and, accordingly, significantly shorten muscle recovery. Study supports efficacy of hyaluronan for wrinkle reduction Toho University Ohashi Medical Center (Japan) Twelve weeks of supplementation with hyaluronan – also known as hyaluronic acid – may improve the “luster” of the skin and reduce wrinkles, says a new study from Japan. Data from a randomized, double-blind, placebo-controlled trial with 60 adults indicated that 120 milligrams per day of Kewpie's hyaluronan ingredients Hyabest (A) and Hyabest (S) LF-P also led to improvements in skin suppleness. “This study showed that the oral ingestion of the [molecular weight] 2 k or 300 k [hyaluronic acid] for 12 weeks suppresses wrinkles and improves the skin's luster and suppleness in people aged 59 years or less who were healthy Japanese men and women over 22 years old. From the above, [hyaluronic acid] consumption is expected to be used as a method to maintain healthy skin,” wrote researchers from Kewpie Corporation and the Toho University Ohashi Medical Center in Clinical, Cosmetic and Investigational Dermatology . Kewpie Corp funded the study. HA and skin The skin contains about 50% of the body's hyaluronan (HA), a component present in every connective tissue. Degradation of HA and collagen is reported to be a cause of wrinkles, with many ingredient suppliers exploring the potential of supplementation to improve skin health from within. Scientists from Kewpie authored a review i published in the Nutrition Journal, which concluded: “The reduction of HA in the skin by intrinsic and extrinsic factors such as aging and ultraviolet radiation, smoking and air pollutants induce dryness in the skin. However, daily HA supplements can moisturize the skin because the metabolites of HA increases the skin moisture content by having an effect on the skin cells. Thus, consuming HA affects skin cell and improves dry skin physiologically. “This review shows that consuming HA moisturizes the skin and employing HA as a dietary supplement makes the skin healthy. We believe that countries worldwide will benefit from this review and consume HA to alleviate dry skin.” The new double-blinded, placebo-controlled study adds to this body of evidence and investigated the effects of the ingredient on wrinkles. The researchers recruited 60 Japanese men and women aged between 22 and 59 to participate in their study. The participants were randomly assigned to one of three groups: Placebo, or a HA formulation using one of two varieties, with a molecular weight of 2k or 300k (Hyabest (A) and Hyabest (S) LF-P, respectively). Both groups received a dosage of 120 mg per day. Three-dimensional analysis of their skin indicated that the HA groups showed a better level of the whole sulcus (grooves in the skin) to volume ratio, wrinkle area ratio, and wrinkle volume ratio, compared to placebo and baseline values. However, only the 300 k (Hyabest (S) LF-P) group showed significantly diminished wrinkles compared with the placebo group. Exercise can make cells healthier, promoting longer life, study finds University of Virginia Whether it's running, walking, cycling, swimming or rowing, it's been well-known since ancient times that doing some form of aerobic exercise is essential to good health and well-being. You can lose weight, sleep better, fight stress and high blood pressure, improve your mood, plus strengthen bones and muscles. “Whether muscle is healthy or not really determines whether the entire body is healthy or not,” said Zhen Yan of the University of Virginia School of Medicine. “And exercise capacity, mainly determined by muscle size and function, is the best predictor of mortality in the general population.” Yan and colleagues have completed a study in mice that, for the first time, shows that just one bout of moderate-to-intense exercise acts as a “stress test” on mitochondria in muscles. They discovered that this “stress test” induced by aerobic exercise triggers a process called mitophagy, where the muscle disposes of the damaged or dysfunctional mitochondria, making the muscle healthier. Yan compares exercise-induced mitophagy to a state vehicle inspection that removes damaged cars from the streets. “Aerobic exercise removes damaged mitochondria in skeletal muscle,” Yan said. “If you do it repeatedly, you keep removing the damaged ones. You have a better muscle with better mitochondrial quality. We clean up the clunkers, now the city, the cell, is full of healthy, functional cars.” How Exercise Removes Mitochondria ‘Clunkers' For this study, Yan and colleagues assessed the skeletal muscle of a mouse model where they had added a mitochondrial reporter gene called “pMitoTimer.” The mitochondria fluoresce green when they are healthy and turn red when damaged and broken down by the cell's waste-disposal system, the lysosomes. The mice ran on a small treadmill for 90 minutes and Yan's team observed mitochondrial stress (signs of “state inspection”) and some mitophagy (towing of the clunkers) at six hours after exercise. Yan explained that exercise in these mice also stimulated a kinase called AMPK, which in turn switched on another kinase, Ulk1. These chemical reactions appear to be important in control of the removal of dysfunctional mitochondria. “When its turned on, Ulk1 activates other components in the cell to execute the removal of dysfunctional mitochondria,” Yan said. “It's analogous to a 911 call where a tow truck removes the clunkers. However, we still do not know how these activities are coordinated.” LED lights safer, more effective in producing Vitamin D3 than sunlight Boston University Research published in Scientific Reports showsthat light from RayVio's 293nm ultraviolet (UV) LED is more efficient than sunlight at producing vitamin D3 in skin samples. Tyler Kalajian and his research team, led by Dr. Michael F. Holick, Ph.D., M.D., and supported by Boston University School of Medicine and a Boston University Ignition Award, found that skin samples exposed to RayVio's UV LED for just 0.52 minutes produced more than twice as much vitamin D3 as samples exposed to 32.5 minutes of sunlight. “We tested ultraviolet LEDs from different sources and at different wavelengths. LED showed the most significantpotential for vitamin D3 production in the shortest amount of time,” said Dr. Holick, a Professor of Medicine, Physiology and Biophysics atBoston University School of Medicine, and endocrinologist at BostonMedical Center. “This study will lead to a new generation of technologythat can be labeled as photopharmacology in which the use of LEDswith targeted wavelengths can cause specific biologic effects in humanskin to help treat and prevent chronic illnesses.” Vitamin D deficiency is associated with osteoporosis, rickets and other metabolic bone diseases and is more prevalent in northern and southern latitudes where sunlight is limited for a significant part of the year. This device for making vitamin D is ideally suited for patients with fat malabsorption syndromes including inflammatory bowel disease and gastric bypass surgery. The research shows that LEDs could be used for treating patients that are vitamin D deficient. A vitamin D3 producing UV LED device could be used on skin areas that experience less exposure to sunlight such as upper legs and arms and abdomen and back thus minimizing risk for developing non-melanoma skin cancer. The UV LED device also emits a much narrower band of UVB light and thereby decreasing likelihood of skin damage that can occur when the skin is exposed to higher wavelengths of UV radiation.

In this edition of the Bottom Line Advocator Podcast, Michael F. Holick, MD, PhD, joins Bottom Line President Sarah Hiner to discuss the scientific evidence that demonstrates vitamin D’s crucial role in our fight against COVID-19 and the best ways you can achieve healthy levels of this enormously powerful nutrient. A professor of medicine, physiology and biophysics at Boston University Medical Center, Dr. Holick is author of The Vitamin D Solution: A 3-Step Strategy to Cure Our Most Common Health Problems Topics covered include… • Groundbreaking early research on vitamin D (4:23 – 6:19) • The link between kidney disease and weak bones (6:19 – 6:58) • Mother Nature’s wisdom around the “sunshine vitamin” (6:58 – 7:43) • The surprising ways vitamin D keeps us healthy (7:43 – 9:39) • Vitamin D’s healing effects on psoriasis (9:39 – 10:22) • The link between vitamin D deficiency and pregnancy complications, cancer, multiple sclerosis, Alzheimer’s and more (10:22 – 11:25) • Why vitamin D helps fight COVID-19 and autoimmune disorders (11:25 – 13:24) • Remarkable research on vitamin D and COVID-19 (13:24 – 15:43) • Optimal levels of vitamin D (15:43 – 17:51) • Vitamin D deficiency in hospitalized COVID-19 patients (17:51 – 20:33) • High-risk groups for COVID-19 are inherently vitamin D–deficient (20:33 – 22:44) • A free app that helps you track your vitamin D levels (22:44 – 23:44) • Why vitamin D doesn’t get more respect and its effect on the COVID-19 vaccine (23:44 – 24:41) • Too much vitamin D can cause harm to these individuals (24:41 – 26:08) • Can you get too much vitamin D? (26:08 – 28:10) • The myth about vitamin D-3 versus vitamin D-2 (28:10 – 29:22) • Vitamin D use in those with kidney disease (29:22 – 29:59) • How skin pigment affects vitamin D levels (29:59 – 32:06) • Why there’s no vitamin D in human breast milk (32:06 – 32:51) • How quickly can I increase my vitamin D levels? (32:51 – 34:47) • Stress and vitamin D levels (34:47 – 35:27) • Symptoms of vitamin D deficiency (35:27 – 36:24) • The “sweet spot” for supplementation and sun exposure (36:24 – 40:22) • Tanning beds and UV light (40:22 – 43:27) • Phytoplankton for vitamin D (43:27 – 44:03) • The right vitamin D supplement for vegans (44:03 – 45:14) • Why everyone needs a vitamin D supplement (45:14 – 48:47 Learn more about Michael F. Holick, MD, PhD, and his work at DrHolick.com. You can connect with and stay in touch with Sarah at her website www.bottomlineinc.com! Find Bottom Line on Facebook @WeAreBottomLine and at Bottom Line Inc. on  www.linkedin.com. And if you enjoyed this podcast, please share a review so that more people can benefit from Be sure to subscribe to the Bottom Line Advocator Podcast with Sarah Hiner on Apple Podcasts, Spotify and Stitcher.

According to researchers from the Vitamin D, Skin, and Bone Laboratory, Section Endocrinology, Diabetes, Nutrition, and Weight Management, Boston University School of Medicine, and the Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, “although it is still debatable what level of serum 25-hydroxyvitamin D is optimal, it is advisable to increase vitamin D intake and have sensible sunlight exposure to maintain serum 25-hydroxyvitamin D at least 30 ng/mL (75 nmol/L), and preferably at 40–60 ng/mL (100–150 nmol/L) to achieve the optimal overall health benefits of vitamin D.”I opened with this definitive statement on what blood level of the tested form of Vitamin D—25(OH)D–is necessary to achieve, since the Boston co-study author, Michael F. Holick, in my opinion, is one of the world's leading experts on this topic.Immunologic Effects of Vitamin D on Human Health and Disease—the study–which appeared in the December issue of Medicine & Science in Sports & Exercise, qualifies current recommendations of Vitamin D deficiency—a blood level of less than 20 ng/mL—and insufficiency—between 20 to 30 ng/mL–with a specific blood range–“preferably 40-60 ng/mL”—for the, “optimal overall health benefits of Vitamin D.”The researchers comment that vitamin D, which regulates calcium and phosphate metabolism, is critical in maintaining skeletal integrity, while also functioning as an immunomodulatory hormone—a seco-hormone. Holick and his fellow co-author, Nipith Charoenngam, note that there is a vitamin D link with the incidence and severity of many disorders, such as psoriasis, multiple sclerosis, rheumatoid arthritis, type 1 diabetes, and infectious diseases—specifically, “experimental studies have shown that vitamin D has significant biologic activities on the innate and adaptive immune systems.”Holick and his Thailand associate executed a review examining the biologic effects of vitamin D on the immune system and its association with several types of immune-related diseases and conditions, in addition to the impact that Vitamin D has relative to prevention and treatment of immune-related diseases.Vitamin D gains access to the human system via sunlight exposure, diet, and supplements. The active forms include vitamin D2—ergosterol—obtained in the diet from yeast, sun dried and irradiated mushrooms, and plants, while the active form—D3—is manufactured internally from dietary sources, such as cod liver oil and oily fish.Once in the system, the liver converts both D2&3 to 25(OH)D, then the kidneys complete the task by transforming the 25(OH)D to its active form—1,25(OH)2D.In order to meet the recommended vitamin D intake, the Endocrine Society Guidelines state that adults, who are at risk for vitamin D deficiency, should strive for 1500-2000 iu's (international units) per day—with an upper limit of 10,000iu's.The review concluded that, among other variables, “most of the evidence, to date, suggests that maintenance of a healthy vitamin D status is important for modulating the body's immune function. Low serum levels of 25(OH)D are associated with multiple immune-related diseases, including autoimmune disorders and infectious diseases.”Read the rest at MackieShilstone.com.

With summer right around the corner, huge kiosks of sunscreen are on display at stores everywhere, reminding us to fear the sun. We’ve been told for years that sunlight is something to guard against - and, of course, most of us know someone who’s had a suspicious mole removed. But we also know the sun is needed for vitamin D production - plus, it just feels great on our skin! And obviously our ancestors weren’t slathering on Coppertone when they left the cave. It seems to be a no-win situation until you learn the facts about sunlight. NBT Scientific Director Megan Hall is with me today to talk about the critical role of sunlight for health and wellness. She outlines the many benefits of sun exposure that go far beyond vitamin D production and sets the record straight on UVA vs UVB rays, skin cancer, and how sunscreen is actually working against you. Here’s the outline of this interview with Megan Hall: [00:00:11] Megan's new puppy. [00:03:35] Podcast w/ Kira Furie: Breaking Through the Diet Culture: Medical Care for Every Size. [00:05:42] Vitamin D and conditions associated with low levels. [00:07:40] Book: Hidden Valley Road: Inside the Mind of an American Family, by Robert Kolker. [00:08:22] Optimal Levels and dosing of Vitamin D. [00:12:55] Vitamin D Calculator. [00:13:47] COVID-19 and Vitamin D; Studies: 1. Glicio, El James. "Vitamin D Level of Mild and Severe Elderly Cases of COVID-19: A Preliminary Report." Available at SSRN 3593258 (2020); 2. De Smet, Dieter, et al. "Vitamin D deficiency as risk factor for severe COVID-19: a convergence of two pandemics." medRxiv (2020); 3. D’Avolio, Antonio, et al. "25-hydroxyvitamin D concentrations are lower in patients with positive PCR for SARS-CoV-2." Nutrients 12.5 (2020): 1359; 4. Meltzer, David O., et al. "Association of Vitamin D Deficiency and Treatment with COVID-19 Incidence." medRxiv (2020). [00:15:20] Vitamin D and ACE2. [00:17:46] Benefits of sunshine beyond vitamin D. [00:18:01] Circadian rhythm. [00:18:29] Satchin Panda; Podcast: How to Use Time-Restricted Eating to Reverse Disease and Optimize Health. [00:18:30] Bill Lagakos; Podcast: Why You Should Eat Breakfast (and Other Secrets of Circadian Biology). [00:18:35] Nitric oxide. [00:19:01] Malcolm Kendrick; Podcasts: Why Cholesterol Levels Have No Effect on Cardiovascular Disease (And Things to Think about Instead) and A Statin Nation: Damaging Millions in a Brave New Post-health World. [00:19:25] Homocysteine; glycocalyx. [00:21:20] Ivor Cummins; Podcasts with Ivor: How Not to Die of Cardiovascular Disease and Coronary Artery Calcium (CAC): A Direct Measure of Cardiovascular Disease Risk. [00:22:24] UV exposure suppresses symptoms of metabolic syndrome; Study: Geldenhuys, Sian, et al. "Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D in mice fed a high-fat diet." Diabetes 63.11 (2014): 3759-3769. [00:22:54] Melatonin. [00:25:39] Serotonin; Study: Lambert, Gavin W., et al. "Effect of sunlight and season on serotonin turnover in the brain." The Lancet 360.9348 (2002): 1840-1842. [00:26:26] Immunomodulation. [00:26:45] Vitamin D and Multiple Sclerosis; Reduced risk of MS: van der Mei, Ingrid AF, et al. "Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study." Bmj 327.7410 (2003): 316; Reduced risk of depression and fatigue: Knippenberg, S., et al. "Higher levels of reported sun exposure, and not vitamin D status, are associated with less depressive symptoms and fatigue in multiple sclerosis." Acta Neurologica Scandinavica 129.2 (2014): 123-131; MRI neurodegeneration scores inversely associated with sun exposure: Zivadinov, Robert, et al. "Interdependence and contributions of sun exposure and vitamin D to MRI measures in multiple sclerosis." J Neurol Neurosurg Psychiatry 84.10 (2013): 1075-1081. [00:27:20] UV treatment increased glucagon-stimulated insulin secretion; Study: Colas, C., et al. "Insulin secretion and plasma 1, 25-(OH) 2D after UV-B irradiation in healthy adults." Hormone and metabolic research 21.3 (1989): 154-155. [00:27:27] Prevention and treatment of skin conditions; Study: Søyland, E., et al. "Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis." British Journal of Dermatology 164.2 (2011): 344-355. [00:27:49] Sun exposure related to life expectancy; Study: Lindqvist, Pelle G., et al. "Avoidance of sun exposure as a risk factor for major causes of death: a competing risk analysis of the Melanoma in Southern Sweden cohort." Journal of internal medicine 280.4 (2016): 375-387.  [00:30:14] Outline of this interview. [00:31:04] UVA and UVB rays; UVB needed for Vitamin D Production: Wacker, Matthias, and Michael F. Holick. "Sunlight and Vitamin D: A global perspective for health." Dermato-endocrinology 5.1 (2013): 51-108. [00:31:31] Inverse correlation between dose of UVB and melanoma: Study: Godar, Dianne E., Madhan Subramanian, and Stephen J. Merrill. "Cutaneous malignant melanoma incidences analyzed worldwide by sex, age, and skin type over personal Ultraviolet-B dose shows no role for sunburn but implies one for Vitamin D3." Dermato-endocrinology 9.1 (2017): e1267077. [00:33:43] Sunscreens; coral bleaching: Downs, Craig A., et al. "Toxicopathological effects of the sunscreen UV filter, oxybenzone (benzophenone-3), on coral planulae and cultured primary cells and its environmental contamination in Hawaii and the US Virgin Islands." Archives of environmental contamination and toxicology 70.2 (2016): 265-288.  [00:43:20] Join the discussion on the NBT forum when you support us on Patreon.

Everything you need to know about Vitamin D: What it is, what to measure, various effects on: health, mental health, cognition, autoimmune disease, the brain, our genes etc. The optimal range of Vitamin D and instructions for getting your vitamin D from the sun and supplements.  Professor Michael F. Holick is an internationally recognized expert in the field of Vitamin D. He was responsible for identifying 25-hydroxycitamin D3 as the major circulating form of vitamin D in human blood. He has published over 800 journal articles, book chapters, editorials, and proceedings. He has also written 13 books including the best seller The Vitamin D Solution. For more episodes, inspiration and more, follow André at: Instagram: instagram.com/HealthPsychologyAndHumanNature Facebook: facebook.com/HealthPsychologyAndHumanNature Friends, enjoy and have a great day. 

Is there a correlation between autoimmune diseases and Vitamin D levels? How much Vitamin D should you take? What if you are pregnant? In today’s episode, Dr. Hotze is joined by the leading authority on Vitamin D and the person who discovered its active form, Dr. Michael Holick. Michael F. Holick, Ph.D., M.D. is Professor of Medicine, Physiology and Biophysics; Director of the General Clinical Research Unit; and Director of the Bone Health Care Clinic and the Director of the Heliotherapy, Light, and Skin Research Center at Boston University Medical Center. He is also the author of The Vitamin D Solution: A 3-Step Strategy to Cure Our Most Common Health Problems. Watch now and learn all the health benefits of this amazing hormone and subscribe to our podcasts at www.hotzepodcast.com to learn how to obtain and maintain health and wellness, naturally! Take our free symptom checker quiz at: https://www.hotzehwc.com/symptom-checker/

Is there a correlation between autoimmune diseases and Vitamin D levels? How much Vitamin D should you take? What if you are pregnant? In today’s episode, Dr. Hotze is joined by the leading authority on Vitamin D and the person who discovered its active form, Dr. Michael Holick. Michael F. Holick, Ph.D., M.D. is Professor of Medicine, Physiology and Biophysics; Director of the General Clinical Research Unit; and Director of the Bone Health Care Clinic and the Director of the Heliotherapy, Light, and Skin Research Center at Boston University Medical Center. He is also the author of The Vitamin D Solution: A 3-Step Strategy to Cure Our Most Common Health Problems. Watch now and learn all the health benefits of this amazing hormone and subscribe to our podcasts at www.hotzepodcast.com to learn how to obtain and maintain health and wellness, naturally! Take our free symptom checker quiz at: https://www.hotzehwc.com/symptom-checker/

Har du noengang lurt på hvor lenge du burde være i sola? Eller hva er D-vitamin som mange eksperter snakker om? Får du nok D vitamin fra et normalt kosthold? Dagens gjest er Dr Michael F. Holick en professor i medisin, fysiologi og biofysikk. En av verdens fremste på Vitamin D, Michael Holick har gjort funn som har ført til nye terapier for metabolske bensykdommer, hypokalcemiske lidelser og psoriasis. Han er forfatter av en rekke bøker blant annet boken The Vitamin D Solution, og mer enn 400 publikasjoner om biokjemi, fysiologi, metabolisme og fotobiologi av vitamin D og patofysiologien av vitamin D-mangel.  i tillegg er Michael direktør for den generelle kliniske forsknings enheten og direktør i Bone Health Care Clinic og direktør for helioterapi, lys og hudforskningsenter ved Boston University Medical Center. Sjekk også ut appen Dminder som forteller deg hvor lenge du trenger å være i sola der du befinner deg. Du kan også besøke hjemmesiden til Michael for å se hvilke verdier han anbefaler deg her I dagens episode er vi innom følgende:  Hva er egentlig D-vitamin Er det mulig å redusere risiko for influensa med hele 42% Vitamin-D regulerer over 200 gener i hjerte-kar systemet Reduser risikoen for hjerteinfarkt med 50% og få 100% større sannsynlighet for å overleve et infarkt. Mangel på Vitamin-D gir høyere blodtrykk Hvorfor vi som lever i Norge har 10-15x større sannsynlighet for Diabetes Hvor mye D-vitamin må kroppen din ha hver eneste dag Er det mulig å ta for mye tilskudd Hva er symptomer på for lite D vitamin Hvorfor er D-vitamin så utrolig viktig for oss Hvilke sykdommer kan du få pga for lite D-vitamin Hvor lenge må du være i sola for å begrense sannsynligheten for høytblodtrykk og sykdommer. Bor du i Norge produserer kroppen din IKKE vitamin D 6mnd av året. Er du født på vinteren har du høyere risiko for Schizofreni senere i livet. Høyere vitamin D verdier reduserer risiko for keisersnitt med 200 til 300% Hvor høye verdier burde du ha mens du er gravid Hvor mye D Vitamin burde små barn ha hver dag Hvorfor huden din blir rød når du er i sola Bruk av solkrem Den farligste formen for hudkreft forekommer der du IKKE får sol. Med mer..

Michael F. Holick, PhD MD, Boston University Medical Center gives an energetic talk on the positive impacts of sunlight on your health. How can we balance current thinking on the negative effects of sun exposure with new research on its benefits? How does sunlight help in the production of vitamin D? Join Dr. Holick as he explains how sunlight reaches us, how it is absorbed by the skin and much more. Series: "Vitamin D for Public Health - Integrating Sunshine, Supplements and Measurement for Optimal Health 2014" [Health and Medicine] [Show ID: 29075]

Michael F. Holick, PhD MD, Boston University Medical Center gives an energetic talk on the positive impacts of sunlight on your health. How can we balance current thinking on the negative effects of sun exposure with new research on its benefits? How does sunlight help in the production of vitamin D? Join Dr. Holick as he explains how sunlight reaches us, how it is absorbed by the skin and much more. Series: "Vitamin D for Public Health - Integrating Sunshine, Supplements and Measurement for Optimal Health 2014" [Health and Medicine] [Show ID: 29075]