Podcasts about Endocrine Society

Vitamin D recommendations in 1941 began this debate. Over the years, updated guidelines have continued to spark controversy and debate in the field of vitamin D research.In this episode of Daily Value, we look at the recent “Vitamin D-ilemma” reinvigorated by the Endocrine Society's updated 2024 guidelines. These new recommendations have dialed back routine testing and supplementation targets, igniting pushback from leading researchers who argue we might be overlooking significant health benefits (including reduced risks for 8 out of the top 10 leading causes of death). Join us as we Look at the evolving science behind vitamin D, why randomized trials and observational studies seem to tell different stories, and how you can practically navigate these conflicting recommendations to optimize your own health.00:00 Introduction: The Vitamin D Controversy01:00 Historical Guidelines and Shifts01:54 The 2011 Guidelines and Their Impact03:57 The 2024 Update: A New Debate06:13 Understanding Vitamin D's Role in the Body07:29 Clinical Trials vs. Observational Studies09:13 Health Benefits of Higher Vitamin D Levels11:58 Challenges in Vitamin D Research15:56 Practical Recommendations for Optimal Vitamin D19:32 Conclusion: Striving for Optimal HealthPMID: 39861407PMID: 38828961PMID: 37004709PMID: 30992519Support the show

Dr. Florence Comite, MD is a clinician-scientist, endocrinologist, and the leading expert in the fields of healthy longevity and precision medicine. Her international reputation stems from her innovative approach to leveraging proprietary clinical and wearable data in her private clinical and virtual practice to detect, predict, and reverse biological aging, while optimizing health and vitality.   As a graduate of Yale School of Medicine, Dr. Comite served as a faculty member for twenty-five years with a distinguished triple appointment in Endocrinology (Internal Medicine and Pediatrics) and Reproductive Endocrinology (Gynecology and Andrology). During her career, she trained at the National Institutes of Health and founded Women's Health at Yale, establishing the nation's first women-only clinic.   In 2005, Dr. Comite founded the Comite Center for Precision Medicine & Healthy Longevity in New York City, where she developed the groundbreaking Nof1™ clinical process, treating each patient as a single subject clinical trial. The Center's success has led to expansions in Palo Alto and Miami Beach. Her innovative approach has attracted a global clientele, including forward-thinking physicians, industry leaders, and entrepreneurs, each receiving personalized healthcare interventions tailored to their individual needs. Her commitment to advancing medical science is evident through her extensive research and publications in prestigious journals such as the New England Journal of Medicine, JAMA: The Journal of the American Medical Association, and the Journal of the Endocrine Society. Dr. Comite's pioneering research spans across children, women, and men, recognizing the critical role of the entire system in aging and disease.   In 2013, she authored the bestselling book "Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life," focusing on androgen deficiency and vitality in aging men. Her next book, "Invincible: Eliminate the Disorders of Aging for a Healthy, Long Life," will be published by Little Brown, Spark in Spring 2026. Through her startup Groq Health, Dr. Comite is scaling her precise methodology of precision medicine to a digital clinic delivered virtually.   As a sought-after keynote speaker, Dr. Comite continues to captivate audiences worldwide, sharing her expertise and vision for the future of precision medicine and healthy longevity.

I'm joined by board-certified general surgeon Dr. Lee Howard, who walked away from traditional medicine. Why he feels traditional medicine doesn't really help its patients plus we cover what supplements are good for everyone to take, how to navigate allergy season with kids, what the heck the MTHFR gene is, how we should be approaching our kids' health, why were gonna start to hear more and more about creatine, ways we can help the aging process, plus perimenopause and menopause- how to minimize symptoms and recognize when we start to enter that stage. And we cover once and for all what those silly eye twitches are from. Clip 3: Low Testosterone and Alzheimer's RiskMost people think of testosterone as a hormone that just affects sex drive or muscle mass. But the brain is actually one of its biggest targets. A massive 2023 study from the University of Sydney looked at older men and found something shocking: men with low testosterone had a 26% higher risk of developing Alzheimer's disease. And we're not talking about late-stage life—these patterns start decades earlier. Testosterone helps regulate inflammation in the brain, supports memory circuits, and even promotes the growth of new neural connections. When levels drop too low, especially without being noticed, the brain becomes more vulnerable to decline. Here's the kicker: most men never get their levels checked. And if they do, the 'normal range' is often outdated or way too broad. What's normal for a 75-year-old is not what you want at 45. I've had women come in concerned about their partner's mood, irritability, even motivation—and it turns out his testosterone was tanked. If you're in a long-term relationship and your partner is acting like a different person, you're not imagining it. And getting his hormones evaluated might be the missing link to helping him feel like himself again—and preventing cognitive decline down the line.Study source: University of Sydney & Neuroscience Research Australia (2023)https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.1252Clip 5: Gut Health and MoodThere's a direct, two-way communication line between your gut and your brain—and researchers now believe that the gut may play just as much of a role in mental health as the brain itself. A major review from 2024 showed that people with poor gut diversity were significantly more likely to suffer from depression and anxiety, even when diet and lifestyle were controlled. Why? Because 90% of your serotonin is actually made in your gut. If your microbiome is inflamed or out of balance, your body literally has fewer raw materials to make feel-good brain chemicals. On top of that, gut inflammation sends stress signals to your brain—keeping you in a low-level “fight or flight” state, even when nothing's wrong. And if you've ever felt brain fog, irritability, or sadness after a weekend of sugar and alcohol… this is why. What's exciting is how quickly you can make a shift. Just increasing your fiber, adding fermented foods, or taking the right probiotic can make a measurable difference in just a few weeks. This isn't woo. This is the future of psychiatry. And if you've done therapy, made lifestyle changes, but still don't feel right—check your gut. It might be where your healing needs to start.Study source: Review from the Polish Society of Gastroenterology (2024)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811453Clip 8: Hormone Imbalances and MarriageYou'd be shocked how many couples come into my office thinking they have a communication problem—when what they really have is a hormone problem. He's irritable, unmotivated, maybe withdrawing. She's exhausted, anxious, snapping at small things. They think they've grown apart. They think the spark is gone. But when we test their hormones—testosterone, cortisol, DHEA, thyroid—what we find is that their biochemistry is off. And once we start restoring balance, everything shifts. The mood improves. The intimacy returns. The little things don't feel so overwhelming. We now have solid evidence that hormonal health directly impacts emotional regulation, sexual desire, and even empathy. And if both partners are dysregulated, it can feel like the marriage is falling apart—when really, it's just that their physiology is out of sync. This isn't a relationship failure. It's a hormone crisis. And once you name it, you can fix it. I've seen couples on the brink of divorce completely turn things around—because we stopped blaming each other and started healing their bodies.Study source: APA + American Journal of Men's Health (2023–24)https://journals.sagepub.com/doi/10.1177/15579883231166518Clip 11: Whole Milk in Schools Might Actually Be SmarterFor decades, schools have pushed low-fat or skim milk, based on outdated beliefs about fat and weight. But new evidence is flipping that script. A growing body of research now shows that children who drink whole milk are actually less likely to be overweight than those drinking low-fat milk. Why? Because fat makes food more satisfying. It helps with blood sugar regulation and keeps kids fuller longer—so they're less likely to snack on junk later. In 2025, there's increasing pushback from pediatricians and nutrition researchers against the one-size-fits-all low-fat approach. Some school districts are already considering bringing whole milk back, and they're seeing better nutrition outcomes. Whole milk also contains essential nutrients like vitamin D and calcium in more bioavailable forms, especially when paired with fat. It's time we stop fearing fat—especially when the data shows that cutting it hasn't actually reduced childhood obesity. In fact, we may have made things worse. So if your kid likes whole milk, don't feel guilty. It might just be the more nourishing option after all.Study source: Associated Press report (2025)https://apnews.com/article/e4868fdc2dc4e85aeb9375edcd27da49Clip 13: Hormone Fluctuations and Depression in WomenOne of the biggest blind spots in women's health is how powerful hormone fluctuations are—especially on mood. A 2025 study published in Biomedical Reports found that estrogen and progesterone shifts during puberty, pregnancy, postpartum, and perimenopause play a massive role in rates of depression. This isn't just anecdotal. These hormonal changes alter brain chemistry, sensitivity to stress, and even how the body processes trauma. In puberty, many girls who were previously confident begin to struggle with mood and self-esteem—but instead of checking hormones, we tell them to tough it out. In postpartum, we're finally starting to talk about depression more—but the hormonal crash that happens after birth still catches most women off guard. And in perimenopause, where mood swings and anxiety often resurface, women are still too often told it's “just part of aging.” It's not. It's biology. And the good news is, once you understand that hormones are a major player, you can treat the root cause instead of just masking symptoms. Whether it's bioidentical therapy, lifestyle shifts, or targeted nutrients, women deserve to know that their brains and their hormones are on the same team—and that relief is possible.Study source: Biomedical Reports (2025)https://pubmed.ncbi.nlm.nih.gov/40083602Clip 14: Social Media Changes Teen Brain WiringWe now have MRI data showing that the more often a teen checks social media, the more their brain becomes wired for external validation. In a study from UNC Chapel Hill, researchers found that teens who compulsively checked platforms like Instagram or Snapchat showed measurable changes in the brain's reward centers. These areas lit up more intensely over time, meaning their brains were becoming increasingly sensitive to likes, comments, and digital attention. This isn't just about being distracted. It's about a neurological shift in what they find rewarding—and that shift can impact everything from self-worth to emotional regulation. The researchers even found that this pattern predicts increased anxiety and depression, especially in girls. And it makes sense—when your self-esteem is tied to a number on a screen, even a small drop in engagement feels like social rejection. So what can parents do? First, understand that this isn't just 'teen stuff.' This is brain development. Second, set tech boundaries that prioritize boredom, creativity, and real-life interaction. Even a two-week break can reset the system. Social media isn't going away—but we have to teach kids how to use it without letting it rewire them.Study source: UNC-Chapel Hill (2023)https://www.unc.edu/posts/2023/01/03/study-shows-habitual-checking-of-social-media-may-impact-young-adolescents-brain-developmenClip 16: Screen Time and Toddlers' SleepSleep is how toddlers consolidate memory, regulate mood, and grow both physically and neurologically. But more and more research is showing that screen exposure—even if it's 'educational'—can seriously disrupt toddler sleep. A study published in JAMA Pediatrics found that children ages 2 to 5 who used screens within an hour of bedtime had shorter total sleep and more fragmented rest. Blue light delays melatonin production. Fast-paced content overstimulates the nervous system. And passive consumption before bed blunts their natural wind-down process. We think of it as relaxing—but their brains don't. What's worse is that these disruptions don't just affect nighttime. They carry over into the next day—affecting focus, mood, and even immune function. That's why experts now recommend at least 60 minutes of screen-free time before lights out—especially for young kids. Replace it with a bath, a book, a calm routine. These rituals help their circadian rhythm sync naturally. Sleep isn't just a health pillar—it's a developmental requirement. And screens may be the single biggest obstacle we're overlooking.Study source: JAMA Pediatrics (2024)https://jamanetwork.com/journals/jamapediatrics/fullarticle/282519Clip 18: Hormone-Disrupting Chemicals = Global Health RiskA sweeping review by the Endocrine Society in 2024 called endocrine-disrupting chemicals a 'global health threat.' These are substances—often found in plastics, pesticides, cosmetics, and even receipts—that can mimic, block, or interfere with your body's hormones. They've been linked to everything from infertility to obesity to neurological conditions and cancer. And they're everywhere. Prenatal exposure can affect fetal brain development. Chronic exposure is associated with thyroid dysfunction and metabolic syndrome. And it's not about one product—it's about cumulative load. What's scary is how underregulated many of these substances are in the U.S. compared to Europe. But what's hopeful is that you *can* reduce your exposure. Swap plastic for glass. Say no to fragrance. Wash produce well. Choose organic when you can. Each swap reduces total burden. This isn't alarmist. This is modern environmental medicine. And it affects every system in your body.Study source: Endocrine Society Global Consensus Statement (2024)https://www.endocrine.org/news-and-advocacy/news-room/2024/latest-science-shows-endocrine-disrupting-chemicals-in-pose-health-threats-globallyClip 19: Gut-Brain Axis and Mental HealthWe used to think the brain controlled everything. Now we know the gut plays just as big a role—especially in mental health. The gut-brain axis is a communication superhighway that links your microbiome to your nervous system. And studies show that disruptions in gut health are strongly linked to anxiety, depression, and even neurodevelopmental conditions like ADHD. Certain gut bacteria help produce neurotransmitters like serotonin and GABA. Others regulate inflammation, which directly impacts mood. A 2025 review of over 50 studies found that targeted probiotics improved symptoms of depression in many patients—sometimes as effectively as medication. What you eat, how you digest, and what lives in your gut may affect your mind more than your therapist knows. That doesn't mean meds aren't useful—but it means we have to zoom out. If your gut is inflamed, your brain is inflamed. And no amount of mindset work can override a body that's chemically out of balance. Heal the gut. Watch what changes.Study source: PubMed Meta-Review on Gut-Brain Axis (2025)https://pubmed.ncbi.nlm.nih.gov/3963000Perimenopause: Recognizing and Addressing Early SymptomsDid you know that up to 90% of women experience symptoms of perimenopause years before menopause actually begins? Despite that, most women are either dismissed by doctors or told they're too young to be entering that phase. Perimenopause can start as early as your mid-30s, and it's not just hot flashes—it's insomnia, anxiety, irritability, brain fog, and cycle irregularities. A study from Stanford's Center for Lifestyle Medicine in 2025 emphasized that when women are supported with hormone therapy earlier—during perimenopause, not just postmenopause—they report significantly better mental clarity, energy, and quality of life. But here's the problem: most conventional providers aren't trained to spot this transition, and women are left thinking it's just stress, parenting, or age catching up with them. When really, it's hormones shifting. Estradiol begins to fluctuate, progesterone declines, and the nervous system takes the hit. Women deserve to know what's happening inside their bodies—and what they can do about it. Simple steps like tracking symptoms, checking hormone levels through saliva or urine testing, and considering targeted bioidentical support can change everything. This isn't about vanity—it's about function, clarity, and reclaiming your life before things spiral. If you've ever thought, 'I just don't feel like myself anymore,' and your labs came back 'normal,' this is your sign to dig deeper. You're not crazy. You're not weak. You're likely perimenopausal. And you deserve care that actually sees you.Study source: Stanford Lifestyle Medicine (2025)https://longevity.stanford.edu/lifestyle/2025/03/06/menopause-hormone-therapy-is-making-a-comeback-is-it-safe-and-right-for-you/Menopause and Muscle Mass: The Critical Role of Resistance TrainingMuscle loss during and after menopause is one of the most overlooked drivers of weight gain, fatigue, and metabolic decline in women. In fact, women can lose up to 10% of their muscle mass in the first five years post-menopause. That's not just a cosmetic issue—it's a health crisis. Loss of muscle means decreased insulin sensitivity, weaker bones, and lower resting metabolic rate. But the good news? It's reversible. A landmark 2025 study from the University of Exeter showed that menopausal women who engaged in just 12 weeks of resistance training experienced a 21% improvement in lower body flexibility and significant increases in strength and mobility. What's even more promising is that these improvements came from just two to three sessions a week using basic strength exercises. Muscle is your metabolic engine. And during menopause, when estrogen drops, protecting that muscle becomes your superpower. This isn't about getting shredded or spending hours at the gym—it's about lifting enough weight to send your body the message that it's still needed. Because when your body doesn't get that message, it starts letting muscle go. This leads to increased fat gain, inflammation, and risk of chronic disease. If you're entering menopause or already postmenopausal and you're not lifting weights, you're missing one of the most effective, protective tools for your long-term health.Study source: University of Exeter (2025)https://news.exeter.ac.uk/faculty-of-health-and-life-sciences/first-of-its-kind-study-shows-resistance-training-can-improve-physical-function-during-menopause/The Importance of Sexual Activity as We AgeHere's something most people don't expect: research shows that sexual satisfaction actually improves with age. A 2025 study published in Social Psychology revealed that older adults reported higher levels of emotional intimacy, comfort, and fulfillment during sex—especially when partnered with someone long-term. It turns out that fewer distractions, better communication, and reduced self-consciousness all contribute to more satisfying experiences in later years. But biology still plays a role. Hormonal shifts—like lower estrogen or testosterone—can affect desire, arousal, and comfort. The good news? These challenges are highly treatable. We now have non-invasive, low-risk treatments like vaginal DHEA, testosterone therapy, or pelvic floor physical therapy that can radically improve function and satisfaction. And here's the key: sexual health isn't just about sex. It's about cardiovascular health, immune health, sleep, and mood. An active sex life improves oxytocin levels, reduces stress, and strengthens the emotional bond between partners. Unfortunately, a lot of providers still don't ask about it. And many people are too embarrassed to bring it up. But this is a health issue—and you deserve support. So if intimacy has changed, bring it into the conversation. Because aging doesn't have to mean disconnect—it can actually mean rediscovery.Study source: PsyPost (2025)https://www.psypost.org/sexual-satisfactions-link-to-marital-happiness-grows-stronger-with-age/Preventing Alzheimer's and Type 2 Diabetes: Blood Sugar and Brain HealthThere's a reason Alzheimer's is now being called 'Type 3 Diabetes.' A 2024 study published in JAMA Network Open found that people with Type 2 Diabetes who kept their A1C in the target range significantly lowered their risk of developing Alzheimer's disease. In fact, risk was reduced by up to 60%. Why? Because insulin resistance doesn't just affect your pancreas—it affects your brain. High insulin impairs memory centers like the hippocampus, increases inflammation, and accelerates plaque formation. That means your morning bagel and soda aren't just spiking your blood sugar—they may be spiking your dementia risk. The solution isn't extreme dieting. It's metabolic awareness. Simple tools like continuous glucose monitors, strength training, walking after meals, and eliminating ultra-processed carbs can dramatically stabilize blood sugar. Add in sleep and stress management, and you've got a recipe for brain protection. Most people wait until symptoms start. But prevention is where the power is. If you have a family history of Alzheimer's or Type 2 Diabetes, take this seriously. Your future brain is being built right now by the food on your plate.Study source: JAMA Network Open (2024)https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2821878Testosterone and Aging: It's Not Just About Sex DriveMost people hear 'testosterone' and immediately think of sex drive. But this hormone does way more than that. Testosterone plays a critical role in muscle maintenance, bone density, energy, focus, and mood. A 2025 review from the HE Clinics found that testosterone levels in men start declining around age 30—and continue to drop about 1% per year. That might sound gradual, but by your late 40s or 50s, it's enough to cause noticeable issues: brain fog, irritability, fatigue, and loss of motivation. What's even more concerning is that low testosterone has now been linked to a 26% higher risk of developing Alzheimer's. The brain literally needs testosterone to function well. The challenge is, many men go undiagnosed because they don't get tested—or they get told their levels are 'normal for their age.' But 'normal' doesn't mean optimal. And restoring optimal levels, especially with bioidentical therapies under medical supervision, has been shown to improve mood, clarity, libido, and physical performance. This isn't about bodybuilder doses or quick fixes—it's about reversing a gradual decline that's robbing men of their edge. If you or your partner feels like something is off, it's worth investigating. Because aging doesn't have to mean decline. It can mean recalibration.Study source: HE Clinics (2025)https://heclinics.com/testosterone-therapy-in-older-men-recent-findings/Why Functional Medicine Is Gaining Ground Over Conventional CareIf you've ever felt dismissed in a 7-minute doctor's appointment, you're not alone. Traditional primary care is built for volume—not personalization. That's where functional medicine comes in. A 2019 study published in JAMA Network Open found that patients receiving care through a functional medicine model saw a 30% greater improvement in health-related quality of life than those in conventional care. Why? Because functional medicine is built around asking better questions, running more comprehensive labs, and looking for root causes—not just masking symptoms. Instead of saying 'your labs are normal,' we ask, 'are you thriving?' We look at hormones, nutrition, sleep, gut health, toxin exposure, and genetics as pieces of a bigger picture. This approach is proactive—not reactive. It focuses on reversing disease, not just managing it. More and more people are turning to this kind of care because they're tired of feeling unseen. If you've been told everything is fine but you still feel off, functional medicine might be the approach you need. You deserve care that listens longer, digs deeper, and treats the whole you.Study source: JAMA Network Open (2019)https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2753520A word from my sponsors:Quince - Get cozy in Quince's high-quality wardrobe essentials. Go to Quince.com/honest for free shipping on your order and 365-day returns. LMNT - Get your free LMNT Sample Pack with any purchase at drinklmnt.com/HONEST. Ritual - Support a balanced gut microbiome with Ritual's Synbiotic+. Get 25% off your first month at Ritual.com/BEHONEST. Happy Squatting. Primal Kitchen - primalkitchen.com/honest to save 20% off your next order with code HONEST at checkout.Fatty15 - You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/HONEST and using code HONEST at checkout.Bilt Rewards - Start earning points on rent you're already paying by going to joinbilt.com/HONEST. For more Let's Be Honest, follow along at:@kristincavallari on Instagram@kristincavallari and @dearmedia on TikTokLet's Be Honest with Kristin Cavallari on YouTubeProduced by Dear Media.This episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct, or indirect financial interest in products, or services referred to in this episode.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

A JAMA Clinical Guidelines Synopsis summarizes the Endocrine Society's most recent recommendations on vitamin D supplementation for disease prevention. Author Sherri-Ann M. Burnett-Bowie, MD, MPH, discusses this and more with JAMA Associate Editor David L. Simel, MD, MHS. Related Content: Vitamin D for Prevention of Disease

Mándanos un mensaje¿Alguna vez has sentido que sigues todas las reglas pero tu cuerpo no responde como esperabas? La respuesta podría estar en tus biomarcadores, esas pequeñas señales químicas que revelan la verdad sobre tu salud mucho antes que cualquier síntoma visible.Organizaciones de saludAmerican Diabetes Association (ADA): https://diabetes.org/American Heart Association (AHA): https://www.heart.org/World Health Organization (WHO): https://www.who.int/National Institutes of Health (NIH): https://www.nih.gov/Centers for Disease Control and Prevention (CDC): https://www.cdc.gov/Endocrine Society: https://www.endocrine.org/American College of Rheumatology: https://www.rheumatology.org/American Association for the Study of Liver Diseases: https://www.aasld.org/Estudios científicos específicosHemoglobina A1C: American Diabetes Association. (2021). Glycemic Targets: Standards of Medical Care in Diabetes. Diabetes Care, 44(Supplement 1): S73-S84.Ferritina y rendimiento: Sim, M., et al. (2019). Iron considerations for the athlete: a narrative review. European Journal of Applied Physiology, 119(7): 1463-1478.Miocinas: Pedersen, B. K. (2019). Physical activity and muscle-brain crosstalk. Nature Reviews Endocrinology, 15(7): 383-392.Perfil lipídico y riesgo cardiovascular: Grundy, S. M., et al. (2019). 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol. Journal of the American College of Cardiology, 73(24): e285-e350.Vitamina D: Holick, M. F., et al. (2011). Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 96(7): 1911-1930.Enzimas hepáticas: Kwo, P. Y., et al. (2017). ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries. The American Journal of Gastroenterology, 112(1): 18-35.Ácido úrico y enfermedad cardiovascular: Borghi, C., et al. (2020). Expert consensus for the diagnosis and treatment of patient with hyperuricemia and high cardiovascular risk. Cardiology, 145(1): 1-10.Variabilidad de frecuencia cardíaca: Shaffer, F., & Ginsberg, J. P. (2017). An Overview of Heart Rate Variability Metrics and Norms. Frontiers in Public Health, 5: 258.Support the showInstagram: andieillanesPágina web: andieillanes.com.mx

Increased prescription of opioid medications like oxycodone and hydrocodone has led to widespread misuse of both prescription and non-prescription opioids. But did you know that opioid misuse can significantly impact the endocrine system? The Endocrine Society recently published a scientific statement titled, “Exogenous Opioids and the Human Endocrine System: An Endocrine Society Scientific Statement.” The statement reviews data on the use and misuse of opioids and discusses recent research on the endocrine-related implications of opioid use. Host Aaron Lohr talks to one of the statement’s authors, Niki Karavitaki, MD, PhD, a professor from the Institute of Metabolism and Systems Research at the University of Birmingham in the United Kingdom. Show notes are available at https://www.endocrine.org/podcast/enp98-opioids-and-the-endocrine-system — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Kate Fryer is the CEO of the Endocrine Society. Kate partners with the board of directors and other member leaders to develop strategies, achieve the organization's mission, and work with staff team members to ensure that all methods and programs are successfully implemented.Host and Founder: Lowell Aplebaum - CEO & Strategy Catalyst at Vista Cova Producer and Operations: Amy Hager - Strategy Advisor at Vista CovaVideo and Audio Editing: Savannah BraggMusic: Slow Burn by Kevin MacLeodLink: https://incompetech.filmmusic.io/song...License: http://creativecommons.org/licenses/b...

Vitamin D gets a lot of attention, and it should, mainly for its known role in bone stability. However, vitamin D has significant additional roles in physiology. Vit D, and its metabolites, also functions as modulator of inflammatory and immune responses. According to a number of recent studies, this important micronutrient plays a complex role in numerous biochemical pathways in the immune system and disorders that are associated with them. In pregnancy, the association of Vit D deficiency and adverse perinatal outcomes has been controversial with conflicting data. Nonetheless, in August 2024, the Endocrine Society published its recommendation (J Clin Endocrin Metabol) for routine supplementation for children, adults older than 75 years, pregnant women, and adults with prediabetes. In this episode, we will review a new publication (Feb 2025) from the Am J Clinical Nutrition regarding low vit D levels in the first trimester and PTB. Could vit D supplementation be the answer for preterm birth prevention? The answer may surprise you! Listen in for details.

What treatment options are available for children and adolescents with obesity? Host Aaron Lohr takes on this topic with Susan J. Woolford, MD, associate professor in the Child Health Evaluation and Research Center at the University of Michigan, and Sarah Giger, MD, a clinical fellow at Cincinnati’s Children’s Hospital. Both took part in the Endocrine Society’s recent obesity fellows conference. This episode is supported by an educational grant from Lilly and Novo Nordisk. Also, this episode is available to listen for 0.5 CME credits, but you must follow the link to the show notes and read the instructions in order to earn those points. Show notes are available at https://www.endocrine.org/podcast/enp97-childhood-obesity-treatment — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: the FDA has a warning about smart phones and medical alerts, a few companies turn their attention to patch pumps, a new study looks at costs/benefits of CGM vs Fingerstick during pregnancy, T1D in the Super Bowl.. and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom  Edgepark Medical Supplies Check out VIVI Cap to protect your insulin from extreme temperatures Learn more about AG1 from Athletic Greens  Drive research that matters through the T1D Exchange The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links:   Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Big warning from the FDA about medical alerts from smart phones. They're warning that they've received multiple reports of users missing or not hearing important medical alerts from their phones, leading to cases of dangerously low blood sugar and even death. But the FDA warns that certain phone settings, such as pausing notifications, may cause patients to miss critical updates. In other cases, connecting the phone to a new audio source, such as a car stereo, could change the volume of the alerts users are accustomed to hearing. They have some recommendations to help, mostly just confirming alarms are working before you need them.. and I'll link up the full story in the show notes. Reading between the lines here, it seems like the problem here may be the thousands of unregulated apps that make health claims – not just for people with diabetes. So it's a good idea to check the apps you're using and the companies that make them. https://www.seattletimes.com/seattle-news/health/patients-using-diabetes-apps-can-miss-critical-alerts-heres-how-to-make-sure-youre-getting-them/ XX What costs less during pregnancy? CGM or finger sticks? In the real word, a new study says CGM costs less… Okay, first keep in mind that the cost savings here wasn't about the glucose monitoring supplies, it was about a lower rate of neonatal ICU admissions. In a base-case analysis in which researchers assumed all women would use seven finger sticks per day as dictated by the American Diabetes Association's guidelines for diabetes management in pregnancy, CGM had a higher per-person cost than SMBG. However, in a real-world analysis in which women with a CGM used three finger sticks per day and those performing SMBG used five finger sticks daily, CGM was more cost-effective. In the real-world analysis, CGM users had a per-person cost of $2,747 for the CGM, $988 for finger sticks and $9,973 for neonatal ICU admissions. For SMBG, finger sticks cost $1,647 and neonatal ICU admission costs were $12,876. The reduction in neonatal ICU admission rates with CGM use led to a mean cost savings of $2,903 in the real-world analysis. “These findings justify paying for CGM devices in type 1 diabetes pregnancies, even in the U.S., which has an expensive health care system,” Polsky said future research should focus on the cost-effectiveness of automated insulin delivery systems in pregnancy.   “Automated insulin delivery use has been shown to improve glycemic outcomes in type 1 diabetes pregnancies, but it is still unclear if it improves maternal or neonatal health outcomes and if it would be cost-beneficial,” Polsky said. https://www.healio.com/news/endocrinology/20250205/cgm-may-lead-to-lower-health-care-costs-for-pregnant-women-with-type-1-diabetes   XX Couple of interesting comments from Medtronic at the recent JP Morgan Chase conference. The CEO says he company is “mainly a type 1 business, moving into type 2,”  He says stated that their patch pumps program remains dynamic.. Medtronic expects its 800-series pump to come in at around half the size of the latest-generation 780G. The post says the company plans for a pivotal study in 2025. Potential features could include extended reservoirs and extended-wear sets, plus a brand-new Android/iOS app. https://www.drugdeliverybusiness.com/medtronic-next-gen-insulin-pumps-coming/ XX Beta Bionics also says they're working on a tubeless patch that they plan to launch in 2027. The company reported the device has two parts. One reusable component holds the electronics that operate the device and motor. A second disposable part includes an adhesive patch, insulin reservoir, insertion device, and the cannula used to deliver insulin. Beta Bionics said the pump is planned for use in people with type 1 diabetes and later will expand its use for people with type 2. The company also reported it is continuing work on an AID system that would, in addition to using insulin to lower blood sugar, also contain glucagon to raise blood sugar. Research is being conducted into dual-hormone systems, but none are available yet for people with diabetes. https://diatribe.org/diabetes-technology/tech-watch-diabetes-tech-news XX New approval for the treatment of diabetic macular edema. Susvimo is the “first and only FDA-approved treatment shown to maintain vision in people with DME with fewer treatments than standard-of-care eye injections,” the release said. This is the second indication for Susvimo, which is also approved for the treatment of wet age-related macular degeneration. https://www.healio.com/news/ophthalmology/20250204/fda-approves-susvimo-for-diabetic-macular-edema XX How about this one… drinking ketones improves heart health, a new small-scale study from the University of Portsmouth has found. This is the first time people with type 2 diabetes (T2D) have been given a drink with ketone esters - a supplement that is meant to plunge your system into ketosis - to monitor the effect on the heart. Ketosis is the metabolic state where your body is forced to burn fats instead of carbohydrates. but more research is needed because we only assessed participants on the day, which means we have no idea what the chronic impact of drinking ketones would be." The study was carried out after research showed  The drug SGLT2i was used to lower glucose in patients with diabetes and longitudinal studies were showing that it was inadvertently protecting the heart. The hypothesis was that the drug induces ketosis and the heart was using ketones, which improved heart health, but the evidence for this was limited so our research set out to prove the connection." https://www.news-medical.net/news/20250205/Drinking-ketones-improves-heart-health-for-people-with-type-2-diabetes.aspx XX Another pump wants into the EU. Modular Medical looks to obtain a CE mark in the first quarter of 2026. The patch pump, MODD1, got FDA clearance last fall. The company says it will be available early this year.. but I haven't heard much about it since the approval.   https://www.drugdeliverybusiness.com/modular-medical-step-forward-ce-mark/ XX New CGM system with a reusable applicator and rechargeable wearable transmitter moves forward. Trinity Biotech announced new pre-pivotal clinical data. This company is based in Ireland and is looking for iCGM approval down the road.. hoping to file with the FDA in 2026. https://www.drugdeliverybusiness.com/trinity-biotech-expects-submit-cgm-fda-2026/ XX Body-weight cycling (also known as yo-yo dieting) has been shown to significantly increase the risk of kidney disease in people with type 1 diabetes, regardless of body mass index (BMI) and other traditional risk factors. This is a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. Participants with greater weight fluctuations experienced a 40% decline in kidney health from baseline values https://www.news-medical.net/news/20250204/Yo-yo-dieting-found-to-harm-kidney-health-in-type-1-diabetes-patients.aspx XX Eli Lilly's profit doubled in the fourth quarter, propelled by its hot-selling diabetes and obesity treatments, and the drugmaker came out with a mostly better-than-expected 2025 forecast. Overall, Lilly's quarterly profit swelled to $4.41 billion. https://apnews.com/article/eli-lilly-fourth-quarter-mounjaro-zepbound-ca026922525a9e3abb1b75d329628bef XX Abbott starts a new campaign all about bias and misconceptions when it comes to diabetes. I'm excited that they seem to have worked here with the Behavioral Diabetes Institute. Nearly 70% believe there is stigma associated with their condition.1 Diabetes as a Punchline: 85% of people living with diabetes say they have seen inaccuracies about diabetes in the media, including on TV shows, movies, and social media, and 40% of people felt that diabetes is often used as the punchline of a joke.1 Abbott's new Above the Bias initiative aims to help others see the world from the perspective of someone living with diabetes. The initiative builds upon efforts by several diabetes organizations, patient advocacy groups, and experts that continue to work to reduce stigma about diabetes.3 People can learn more about Above the Bias and watch the film at AboveBias.com. https://www.prnewswire.com/news-releases/abbotts-above-the-bias-film-reveals-misconceptions-can-impact-diabetes-care-302367723.html   -- When you watch the Super Bowl this weekend, watch for Noah Grey. .he's the Kansas City Chiefs tight end who backs up Travis Kelce and he's lived with type 1 since age 18. Grey spoke to media this week about how he loves to interact with kids who have T1D and their shared love of fruit gummies to treat lows. (sound here) Grey has been an ambassador for Tandem Diabetes and has talked about how he unhooks the pump but keeps his Dexcom on for games.   https://www.yahoo.com/news/noah-gray-talks-helping-kids-010013649.html https://www.newsobserver.com/sports/college/acc/duke/article299730324.html   -- I want to take a moment to personally send my love and sympathy to the Gaskins family. These are the folks behind the amazing Macey's Believer's charity. Janice Gaskins passed away this week after a long fight with breast cancer. I've been reading all of the posts on her Facebook page – this is a woman who touched and changed a lot of lives.. so much for the better. May her memory be a blessing. Her life certainly was.

Mudança de hábitos: O primeiro passo para uma vida melhor é o tema do Papo Empreendedor dessa semana.Quer aprender sobre carreira, marketing, negócios, inovação e muita motivação?Quarta-feira, às 8h, no Papo Empreendedor da @guaruja929fm você vai conhecer melhor as histórias de Dr. Daniel Meller Dal Toé e Thalya Seifer. Dr. Daniel é médico endocrinologista, natural de Criciúma. Iniciou sua trajetória acadêmica no Colégio São Bento durante o ensino fundamental e concluiu o ensino médio no Colégio Marista. Formou-se em Medicina pela Universidade Católica de Pelotas/RS e se especializou em Medicina do Trabalho no Hospital de Clínicas de Porto Alegre (UFRGS).Posteriormente, especializou-se em Endocrinologia na Santa Casa de Misericórdia do Rio de Janeiro e realizou um estágio de aperfeiçoamento na área no Hospital de Clínicas da Universidade de São Paulo (USP). Em 2006, obteve o Título de Especialista em Endocrinologia e Metabologia pela Sociedade Brasileira de Endocrinologia e Metabologia (SBEM).Desde 2006, atua em Criciúma, onde se consolidou como referência em sua área de atuação. É membro titular da Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) e membro ativo da Endocrine Society, nos Estados Unidos. Entre 2017 e 2020, exerceu a presidência da Regional Médica de Criciúma. Atualmente, integra o corpo clínico do Hospital São João Batista em Criciúma e é professor do curso de Medicina da UNESC em Criciúma. Thalya é nutricionista, formada pela Universidade do Sul de Santa Catarina (Unisul) em 2020. Sua atuação é focada em emagrecimento e saúde da mulher, oferecendo um acompanhamento personalizado e baseado em evidências.Realiza atendimentos presenciais na cidade de Orleans, além de consultas on-line, proporcionando flexibilidade e acessibilidade para suas pacientes.Não fique fora dessa!Este programa tem o oferecimento da Destak Transportes, Colégio Satc, Metalúrgica Spilere, Plano de Saúde São José e Unicred de Orleans.#guarujátaon #radio #guaruja #papoempreendedor #grandesempreendedores

There is a lot of interest in automated insulin delivery systems, and they were covered in depth at the Endocrine Society’s Type 1 Diabetes Fellows Series, held earlier this year. Joining host Aaron Lohr to talk about these delivery systems is Grazia Aleppo, MD, a professor of medicine at Northwestern University and a presenter at the T1D Fellows Series. Show notes are available at https://www.endocrine.org/podcast/enp96-automated-insulin-delivery-systems — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

(Conversation recorded on December 2nd, 2024)   One of the central ecological challenges of our time is addressing the plastic and petrochemical pollution that has exploded over the past several decades. This global issue will require the cooperation of all nations. But based on the disintegration of UN negotiations for a treaty on plastic pollution last Sunday, this is easier said than done.  In this special episode, Nate is joined by toxicologist Jane Muncke, who provides an in-depth analysis following the final day of discussions in Busan, South Korea. Together, they explore the complex intergovernmental negotiations that have defined the treaty process, as well as the environmental and health policies that have shaped these conversations in recent years. Will we ever be able to place chemical safety and public health above economic motivations at the global level? Could increased public awareness of the way these seemingly convenient products affect our health and well-being finally shut off the plastic tap? Finally, is it possible for the treaty to go beyond waste management and recycling, to instead move towards reducing the production and consumption of plastics at the source?    About Jane Muncke:  Jane Muncke holds a doctorate degree in environmental toxicology and a MSc in environmental science from the ETH Zurich. Since 2012 she has been working as Managing Director and Chief Scientific Officer at the charitable Food Packaging Forum Foundation (FPF) in Zurich, Switzerland. FPF is a research and science communication organization focusing on chemicals in all types of food contact materials.  Jane Muncke is a full scientific member of the Society of Toxicology (SOT), the Society for Environmental Chemistry and Toxicology (SETAC), the American Chemical Society (ACS) and the Endocrine Society. Since 2019, she has been an elected expert member of the Swiss Organic Farming Association Bio Suisse's committee on trade and processing where she contributes to further developing the standards for processing and packaging of organic food. She is a director of the FAN initiative, a collective of experts warning about resource overshoot, the polycrisis, and related societal collapse.   Show Notes and More Watch this video episode on YouTube   ---   Support The Institute for the Study of Energy and Our Future Join our Substack newsletter Join our Discord channel and connect with other listeners  

It’s been a few years, but we are here with an update on acromegaly, covering prevalence, diagnosis, traditional treatment, new therapies, and current gaps in understanding. Host Aaron Lohr talks again with Maria Fleseriu, MD, professor of medicine and professor of neurological surgery at Oregon Health & Science University School of Medicine and director of OHSU’s Pituitary Center. Dr. Fleseriu also serves on the Board of Directors of the Endocrine Society. Show notes are available at https://www.endocrine.org/podcast/enp94-update-on-acromegaly — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

This week's speakers: Sheila Jeffreys - UK - The pornography revolution Irene Lawrence, Lauren Leggieri, Margot O'Hlfearnain - USA - Protesting the American Academy of Pediatrics Conference Irene Lawrence is the Peaceful Defiance Coordinator for WDI USA, as well as Secretary for the Board. She joined the Board in September of 2023. Lauren Leggieri is a, gay rights activist, working to stop, pediatric gender, transitions in the, United States., Lauren is a, Strategy Director, with the LGBT, Courage Coalition., She focuses on, organizing, volunteers and, direct actions. The, LGBT Courage, Coalition is an, American-based, registered nonprofit, that seeks to, impact culture and, medicine to accept, and support gender, non-conformity in a, non-medicalized, way., Lauren has been, interviewed on and, led podcasts, discussing medical, transitions and the, harms to the, lesbian and gay, community. She, has directed, actions at the 2024, Endocrine Society, Conference in, Boston, MA, the, American Academy, of Pediatrics, Annual Leadership, Meeting in, Chicago, IL, and, the 2024 American, Academy of, Pediatrics, Conference in, Orlando, Florida., She will be leading, an action at the US, Supreme Court for, the US v. Skrmetti, and hearing in Dec '24. Margot is Board Vice, President at, Women's Liberation, Front., Writer/activist in the, interest of women, and girls. MFA/MLS, and degrees Updates from USA & Canada ♀♀♀♀♀♀♀♀♀ Feminist Question Time Enjoying our webinars? If you are a position to make a one-off or recurring donation to support our work, you can find out how to do so (and see our financial reports) at https://www.womensdeclaration.com/en/... - thank-you! ♀♀♀♀♀♀♀♀♀ Women's Declaration International (#WDI) Feminist Question Time is a weekly online webinar (Saturdays 3-4.30pm UK time). It is attended by a global feminist and activist audience of between 200-300. The main focus is how gender ideology is harming the rights of women and girls. See upcoming speakers and register to attend at https://bit.ly/registerFQT. There is also a monthly AUS/NZ FQT, on the last Saturday of the month at 7pm (Canberra, Melbourne, Sydney)/9pm (NZ). Register to attend at https://bit.ly/registerFQTAUSNZ. On Sundays (10am UK time), our webinar series, Radical Feminist Perspectives, offers a chance to hear leading feminists discuss radical feminist theory and politics. Register at https://bit.ly/registerRFP. WDI is the leading global organisation defending women's sex-based rights against the threats posed by gender identity ideology. Find out more at https://womensdeclaration.com, where you can join more than 30,000 people and 418 organisations from 157 countries in signing our Declaration on Women's Sex-based Rights. The Declaration reaffirms the sex-based rights of women which are set out in the Convention on the Elimination of all Forms of Discrimination against Women adopted by the United Nations General Assembly on 18 December 1979 (#CEDAW). Disclaimer: Women's Declaration International hosts a range of women from all over the world on Feminist Question Time (FQT), on Radical Feminist Perspectives (RFP) and on webinars hosted by country chapters – all have signed our Declaration or have known histories of feminist activism - but beyond that, we do not know their exact views or activism. WDI does not know in detail what they will say on webinars. The views expressed by speakers in these videos are not necessarily those of WDI and we do not necessarily support views or actions that speakers have expressed or engaged in at other times. As well as the position stated in our Declaration on Women's Sex-based Rights, WDI opposes sexism, racism and anti-semitism. For more information, see our Frequently Asked Questions (https://womensdeclaration.com/en/abou...) or email info@womensdeclaration.com. #feminism #radicalfeminism #womensrights

Osteoporosis significantly impacts morbidity and mortality in the U.S., with approximately 12.3 million adults (USPSTF) in the United States aged 50 and over expected to be living with the disease. Osteoporotic fractures result in severe consequences such as functional impairment, chronic pain, reduced quality of life, and loss of independence. Furthermore, the clinical and economic burden of osteoporosis is substantial, with annual costs projected to be $25.3 billion by 2025 (AJMC).The U.S. Preventative Task Force (USPSTF) recommends screening and treatment of osteoporosis in adults. Accordingly, CommonSpirit Health, Physician Enterprise has adopted the evidence based guidelines of professional societies, including American College of Physicians (ACP), American Association of Clinical Endocrinologists (AACE), and Endocrine Society, on screening and treatment to prevent osteoporotic fractures. Speakers:Kavita Chawla, MD, MHA, FACP, Primary Care Physician, Kirkland Medical Center, Virginia Mason Franciscan HealthBryan C Jiang, MD, Internal Medicine Endocrinology, Diabetes and Metabolism, Baylor College of Medicine Houston, TexasPanelist:Anne Wright, DMSc, MPAS, PA-C, DFAAPA, System Director Advanced Practice Ambulatory Care, CommonSpirit Health

How do you balance being risk-averse with taking calculated risks that could benefit your organization? Can you think of a time when taking a risk in your organization led to unexpected success or a valuable learning experience?In this episode of Associations Thrive, host Joanna Pineda interviews Kate Fryer, CEO of the Endocrine Society. Kate discusses:How Kate discovered the association world after working as a copy editor for scientific journals, later pursuing a long-term association career.The importance of intentional decision making, and how inattention and inactivity can force you to make the wrong decision, taking choice out of your hands.Her experience starting as a CEO during the pandemic, and the effort she made to establish connections with staff and member leaders virtually.How Kate knew she was ready for a CEO role after realizing she could anticipate and critically evaluate the decisions of her mentor.How the Endocrine Society honestly evaluates their own strengths and weaknesses. Kate says that associations often have a "rose-colored glasses" view of their programs, which leads to some programs having a longer life than really needed..How the Endocrine Society is driving non-dues revenue by leveraging its large reserves to fund an innovation fund that invests in for profit ventures in the association and nonprofit space.Her advice to first time association CEOs: Your first Board meeting is critical to your success. You want Board members to be confident in their decision to hire you as the chief staff executive.References:The Endocrine Society Website

Was man teilweise über Vitamin D hört, klingt fast zu schön, um wahr zu sein. Andererseits deuten hunderte verschiedener Forschungsarbeiten darauf hin, dass Vitamin D zur Vorbeugung einer Reihe von Krankheiten beitragen kann – darunter Osteoporose, Depression, Autoimmun- und Herz-Kreislauf-Erkrankungen. Ärzte empfehlen es. Gesundheits- und Fitnesspodcaster sprechen darüber. Vielleicht geht Dir sogar Deine Lieblingstante damit auf die Nerven. Bei all dem Hype ist die Frage berechtigt: "Solltest Du Vitamin D einnehmen?" Hier sind die Antworten – und die neuesten Fakten über ein faszinierendes Vitamin, das ein wahrer Verwandlungskünstler ist. ____________ *WERBUNG: KoRoDrogerie.de: 5% Ermäßigung auf alles mit dem Code „FMM“ beim Checkout. ____________ Ressourcen zur Folge: Literatur: Ratgeber Nahrungsergänzung – Mark Maslow (kostenlos auf MarathonFitness) Blut: Die Geheimnisse unseres flüssigen Organs* – Ulrich Strunz (Heyne) Vitamin D* – Uwe Gröber, Michael F. Holick (Wissenschaftl. Verlagsgesellschaft) Blutuntersuchung (Selbsttest): Vitamin D Test* von Medivere Präparate: D-Form 2.000 K2+* von FormMed D-Form 2.000 K2+ vegan* von FormMed ____________

Host Aaron Lohr talks with Rita Kalyani, MD, professor of medicine at Johns Hopkins University School of Medicine and president-elect of medicine and science at the American Diabetes Association. Earlier this year, Dr. Kalyani and colleagues published a position statement in The Journal of Clinical Endocrinology & Metabolism titled, “Prioritizing Patient Experiences in the Management of Diabetes and Its Complications: An Endocrine Society Position Statement.” Show notes are available at https://www.endocrine.org/podcast/enp93-patience-experience-in-managing-diabetes — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

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Vitamin D is the subject of a lot of controversy right now after the Endocrine Society made new recommendations in June 2024 suggesting that routine screening for vitamin D was not necessary, and routine supplementation was not beneficial for the average person. Today I'm looking into how they came up with this recommendation and what hundreds of studies have shown over the years, to put this recommendation in context. Everyone agrees that vitamin D is critical for life and no one is suggesting that we don't need it, but questions remain around whether we need to take a supplement or if we can find it naturally, and if so, whether we need to measure blood levels and what the optimal blood level should be.

In this solo episode of The Balanced Bodies Blueprint, Dr. Eryn delves into the latest guidelines on vitamin D from the Endocrine Society. With years of research and clinical trials informing these recommendations, Dr. Eryn breaks down the new Clinical Practice Guideline, “Vitamin D for the Prevention of Disease,” highlighting key points and actionable insights for different age groups and health conditions. Dr. Eryn explains why healthy adults under 75 typically don't need more than the daily recommended intake of vitamin D and discusses the specific populations that might benefit from higher doses, such as children, adolescents, individuals over 75, pregnant people, and those with prediabetes. She also addresses common misconceptions, the role of vitamin D in preventing diseases, and the ongoing debate about the necessity of routine vitamin D testing. Tune in to understand the real impact of vitamin D on your health, learn about the best sources of vitamin D, and get practical advice on supplementation. Whether you're a health enthusiast or just looking to optimize your vitamin intake, this episode is packed with valuable information. www.BalancedBodies.io Coach Vinny Email: vinny@balancedbodies.io Instagram: vinnyrusso_balancedbodies Facebook: Vinny Russo Dr. Eryn Email: dr.eryn@balancedbodies.io Instagram: dr.eryn_balancedbodies Facebook: Eryn Stansfield LEGION 20% OFF CODE Go to https://legionathletics.com/ and use the code RUSSO for 20% off your order!

Robert Lustig, MD, MSL is a Professor of Pediatric Endocrinology at the University of California, San Francisco. Dr. Lustig has become a leading public health authority on the impact sugar has on fueling the diabetes, obesity and metabolic syndrome epidemics, and on addressing changes in the food environment to reverse these chronic diseases.   In his New York Times best selling book Fat Chance: Beating the Odds Against Sugar, Processes Food, Obesity, and Disease, Robert documents both the science and the politics that have led to the current pandemic of obesity and chronic disease. In the Fat Chance Cookbook, Robert provides practical examples for applying healthy eating principles with recipes by Cindy Gershen.   Dr. Lustig is a neuroendocrinologist, with basic and clinical training relative to hypothalamic development, anatomy, and function. Prior to coming to San Francisco in 2001, he worked at St. Jude Children's Research Hospital in Memphis, TN. There, he was charged with the endocrine care of many children whose hypothalami had been damaged by brain tumors, or subsequent surgery, radiation, or chemotherapy. Many patients who survived became massively obese. Dr. Lustig theorized that hypothalamic damage led to the inability to sense the hormone leptin, which in turn, led to the starvation response. Since repairing the hypothalamus was not an option, he looked downstream, and noted that these patients had increased activity of the vagus nerve (a manifestation of starvation) which increased insulin secretion. By administering the insulin suppressive agent octreotide, he was able to get them to lose weight; but more remarkably, they started to exercise spontaneously. He then demonstrated the same phenomenon in obese adults without CNS lesions.   The universality of these findings has enabled Dr. Lustig to weave these threads together into a novel unifying hypothesis regarding the etiology, prevention, and treatment of the current obesity epidemic, and the role of our environment in the biochemical changes that promote weight gain. This has led him to explore the specific role of fructose (half of sucrose and high-fructose corn syrup) as a specific mediator of both chronic disease, and continued caloric consumption. His acclaimed YouTube video, “Sugar: The Bitter Truth” continues its popularity with the lay public.   A native of Brooklyn, New York, Dr. Lustig went to Stuyvesant High School in Manhattan, graduated from Massachusetts Institute of Technology in 1976, and received his M.D. from Cornell University Medical College in 1980. He completed his pediatric residency at St. Louis Children's Hospital in 1983, and his clinical fellowship at UCSF in 1984. From there, he spent six years as a post-doctoral fellow and research associate in neuroendocrinology at The Rockefeller University. He has also been a faculty member at the University of Wisconsin-Madison, and the University of Tennessee, Memphis. In 2013, Dr. Lustig received his Masters in the study of Law from University of California, Hastings to enable him to impact the food industry through policy change.   Dr. Lustig has authored 125 peer-reviewed articles and 73 reviews. He has mentored 20 pediatric endocrine fellows, and trained numerous other allied health professionals. He provides endocrinologic support to several protocols of the Children's Oncology Group. He is the former Chairman of the Ad hoc Obesity Task Force of the Lawson Wilkins Pediatric Endocrine Society, a member of the Pediatric Obesity Practice Guidelines Subcommittee of The Endocrine Society, a member of the Obesity Task Force of the Endocrine Society, a member of the Pediatric Obesity Devices Committee of the U.S. Food and Drug Administration, a member of the Bay Area Board of Directors of the American Heart Association, and a member of the Steering Committee of Health Foods, Healthy Kids of the Culinary Institute of America. He also consults for several childhood obesity advocacy groups.   Dr. Lustig lives in San Francisco with his wife Julie and two daughters. Spare time (what little there is) is spent cooking, theater-going, and traveling.

New guidelines for vitamin D recommendations per the Endocrine Society defy personalized medicine; Highlights from the Institute for Functional Medicine and American Nutrition Association meetings: Protein Power, and are new weight loss drugs a panacea?; Where can I find Wobenzyme? Any substitutes?; Does freezing bananas and cooling rice result in resistant starch?

See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog There is a lot of New Medical Information that is important for patients to make healthy decisions about their care or the care of their loved ones that you won't hear about on the news. For new research to reach you, the public, a researcher or a drug company has to spend a great deal of money for the public relations people to push information into the light.  I compiled the research I thought you might want to know about that has been discovered during the past 6 months. I always use these studies to educate my patients and to change my protocols for treatment, although many of them have been part of my practice for quite a while, because they just confirm what I have been seeing in my Integrative and preventive medical practice for years. The First Group of Discoveries Relate to Menopause,  and the Risks of Being Menopausal The most recent article in Lancet confirmed what has been obvious to me in my GYN practice for years. I am not sure why this actually required a study to prove that Menopause is tied to a higher rate of depression and anxiety, in conjunction with insomnia, higher stress perception, and hot flashes.  This study documented what the loss of estradiol, progesterone and testosterone can do to women in menopause.  The sad fact is that this article doesn't tell the reader what they need to know, how to treat these symptoms. However, I will let you in on a self-discovered fact:  The replacement of the hormones that disappear before and during menopause can be replaced in a non-oral delivery system to treat these symptoms.  I have 40 years of medical practice that proves my findings that agree with the problem, and my treatment with hormones. The Lancet: Menopause tied to mental health issues in certain women A study found that when certain women are menopausal, they increase their risk of Depression, anxiety, bipolar disorder who experienced stressful life events, had poor sleep related to hot flashes, or had previous depressive symptoms of depression were more likely to develop menopause-related mental health problems. Researchers wrote in the journal The Lancet that some women escape the mental health effects of menopause altogether. HealthDay News (3/6) Another recent study about menopause discovers that a lack of estradiol in the post menopause causes women to have trouble thinking. I agree with that revelation, but why doesn't the research take the next step and suggest a treatment to prevent this result of hormone loss?  Why doesn't the research tell us how to help women think by replacing their estradiol? Many other studies confirm that replacing estradiol will delay the onset of dementia by 10 years.  Another study reveals that the replacement of testosterone will delay dementia it 10 more years. These studies occurred over 20 years ago, but this study doesn't cite them. Poor and worsening cognitive function is one of the most frequent complaints of my new patients coming to BioBalance Health® for treatment of menopause and low testosterone with bioidentical hormone pellets. Dr Maupin: I am continually reminded of the importance of testosterone and estradiol replacement is to aging men and women when they come back for their second pellet insertion and review their list of the symptoms they complained of before they started E and T pellets The most frequent response I witness when I ask if a woman's ability to think, do her job and stay organized is completely better after 3 months of Estradiol and Testosterone pellets, is crying with relief!   Many patients are deeply worried that they are developing dementia, specifically Alzheimer's Disease when they first come to me, but are able to go back to work and or experience a renewed quality of life because their ability to think, they can now feel confident in their professions and careers. Dr M Estradiol associations with brain functional connectivity in postmenopausal women Testo, Abigail A. BS1; Makarewicz, Jenna BS1; McGee, Elizabeth MD2; Dumas, Julie A. PhD1 Author Information From the 1Department of Psychiatry 2Department of Obstetrics, Gynecology, and Reproductive Sciences, Larner College of Medicine, University of Vermont, Burlington, VT.  The results illustrate the relationship between estradiol level and functional connectivity in postmenopausal women. They have implications for understanding how the functioning of the brain changes for individuals after menopause that may eventually lead to changes in cognition and behavior in older ages. © 2024 by The Menopause Society I have another problem with studies that should be shared with patients is that they often imply that menopausal women are “crazy” instead of saying that women after menopause develop mental health issues that can be treated with hormone replacement. Women who are menopausal are not mentally ill they are hormone deprived! I view this as a “slam” and divisive attack on aging women. The fact that if we gave women what they need …hormonal replacement ….they would not suffer the symptoms of mental health disorders. Menopause tied to mental health issues in some women A study found that women who experienced stressful life events, who had poor sleep due to nighttime hot flashes, or who had previous depressive symptoms or depression were more likely to have menopause-related mental health problems. Researchers wrote in the journal The Lancet that some women escape the mental health effects of menopause altogether. Full Story: HealthDay News (3/6) The Second Group of Articles Is About The Loss Of Estrogen In Menopause Causes Heart Failure and Atrial Fibrillation.  This article from the European Society of Cardiology reveals that the longer women live without estrogen (e.g. is menopausal), the higher risk of developing heart failure and atrial fibrillation. Once again, there is no mention about how to prevent this disease!  Why can't they study the women who replaced their hormones and compare them to the women who didn't?                             Hormone Therapy May Boost Weight Loss for Postmenopausal Women Who are Overweight or Obese On Semaglutide, Study Finds My practice BioBalance Health® has a weight loss program that is very effective for weight loss using Semaglutides, and terzipatide.  For women who are menopausal we have found that they lose weight much more quickly if they are on E2 and T pellet hormone replacement.  This research article confirms the findings of this study. If you are menopausal and have gained weight after menopause that is hormonal and the faster, you can get on non-oral estradiol and testosterone replacement then you will be more likely to get to your ideal weight! March 18, 2024 Hormone therapy may boost weight loss for postmenopausal women on Semaglutides. Healio (3/18, Welsh) reports, “Hormone therapy was associated with an improved weight-loss response for postmenopausal women with overweight or obesity treated with Semaglutides, according to cohort study results published in Menopause.” In the study, “postmenopausal women on hormone therapy had a higher percentage of total body weight loss at 3 (7% vs. 5%; P = .01), 6 (13% vs. 9%; P = .01), 9 (15% vs. 10%; P = .02) and 12 (16% vs. 12%; P = .04) months of semaglutide treatment compared with no hormone therapy.” How and Why to Treat Metabolic Syndrome  Metabolic Syndrome is a combination of hypertension, high lipids, insulin resistance, obesity, prediabetes or diabetes, large abdominal measurement.  This combination puts patients at risk for heart disease and early death.  Many conditions and outcomes have been associated with metabolic syndrome, but now we have a treatment that can prevent one of the outcomes of this syndrome, the generic drug Metformin ER. Metformin, Cognitive Function, and Changes in the Gut Microbiome Endocrine Reviews, Volume 45, Issue 2, April 2024, Pages 210–226, Published: 21 August 2023 Article history Abstract The decline in cognitive function and the prevalence of neurodegenerative disorders are among the most serious threats to health in old age. Metformin can preserve cognitive function by treating metabolic syndrome and improving the gut biome that produces neurotransmitters. I am not naive enough to believe that the only thing that your brain needs to perform well is two sex hormones (E2 and T).  This new research from the Endocrine Society describes how the generic, inexpensive medication Metformin ER, can help preserve an aging patient's ability to think.  That is primarily because the brain has insulin receptors, and when a patient has insulin resistance brain cells don't receive enough blood-sugar to be able to think!  By taking metformin ER (extended release) plus replacing estradiol plus testosterone in pellet form, the brain gets what it needs (blood sugar) and patients can think again! The second factor the researchers found to be important to brain health and problem solving, is healthy gut bacteria in the intestines.  This requires eating whole foods, especially fruits and vegetables every day, and not eating fast food, alcohol, simple sugars, and preservatives that kill good bacteria. We recommend a daily probiotic by Mega + the lifestyle changes above. If you want to keep your ability to think for your whole life then you need E2 and T in pellet form if you are a woman and T if you are an aging male, plus Metformin ER daily and the above lifestyle changes. Metabolic Syndrome, Obesity, is the Biggest Risk for Cancer Metabolic syndrome may increase cancer risk by 30% People with metabolic syndrome had a 30% higher chance of developing cancer over the course of a decade after diagnosis, according to a study published in the journal Cancer. The researchers also studied inflammation by tracking C-reactive protein, concluding that elevated levels of the protein along with metabolic syndrome were “significantly associated with subsequent breast, endometrial, colorectal and liver cancers.” Full Story: National Public Radio (3/11) The struggle to stay young and healthy is a difficult fight but the most important battle that you will wage as an adult.  If people knew the whole truth, would they stop overeating, drinking, smoking, avoiding exercise, or stop taking illicit drugs?  I can only hope that if we convince people to take care of themselves better and replace the hormones that are missing as soon as they are clinically deficient, then they will also listen to the truth about the various ways to support their health and prevent disease.  I also hope that the doctors who write articles and do research stop treating women like crazy people instead of the gender that actually runs the world and not only nurtures the children but also organizes homes and businesses.  We are NOT crazy when we need hormones to be replaced (PMS, MENOPAUSE), we are experiencing symptoms of hormone-deprivation, and we just need to be treated with the hormones that are missing!

What are endocrine disruptors? Why do endocrine disruptors matter? How are endocrine disruptors affecting your daily life?  Endocrine disruptors matter to us more than we think. The Endocrine Society has even put out a statement that advised to avoid microwaving food in plastic containers and swapping out old non-stick pans for newer ceramic coated to decrease exposure "especially for women who are pregnant or trying to become pregnant!"   I just want to share knowledge with you today and help you start to make small changes to equal BIG results!   Hope you enjoy! Jennifer   P.S. If you stuck around and you're interested in those swaps..here are the links.    These are my top 5 picks for natural products.  When you run out of washing powder. Try: https://earthley.com/product/laundry-detergent/ref/jennifer.coble/ Ready for an all-purpose cleaner swap: Try: https://earthley.com/product/cleaning-spray-concentrate/ref/jennifer.coble/ Ready for a deodorant swap? Try: https://earthley.com/product/mineral-deodorant-plus-natural-deodorant/ref/jennifer.coble/ Leave-in Conditioner swap: Try: https://earthley.com/product/silky-smooth-leave-conditioner/ref/jennifer.coble/ My favorite dry shampoo!! https://earthley.com/product/rosemary-lavender-dry-shampoo/ref/jennifer.coble/   First-time customer!? Use Code: CHOOSENATURAL for 10% off your order! Returning Customer? Use Code: COMEBACK for 10% off your order!

To claim educational credit, please follow the link to the show notes. In a special episode, we discuss a complex, rare disease, fibrodysplasia ossificans progressiva, or FOP. Host Aaron Lohr talks with three guests: Eileen M. Shore, PhD, Cali and Weldon Research Professor in FOP and co-director of the Center for Research in FOP and Related Disorders at the University of Pennsylvania School of Medicine; Elisabeth Marelise W. Eekhoff, MD, PhD, endocrinologist, principal investigator, and medical specialist at Amsterdam University Medical Center in the Netherlands; and Michelle Davis, executive director of the International Fibrodysplasia Ossificans Progressiva Association. This episode is certified for 0.5 American Medical Association Physician’s Recognition Award (AMA PRA) Category 1™ credits and 0.5 American Board of Internal Medicine Maintenance of Certification (ABIM MOC) points. If you want those credits and points, you will have to browse to the Endocrine Society’s Center for Learning, take a pre-test, listen to this episode there, then take a post-test. This episode is supported by an educational grant from Ipsen Biopharmaceuticals Inc. Show notes, including link to the Center for Learning, are available at https://www.endocrine.org/podcast/enp84-fibrodysplasia-ossificans-progressiva — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Dr. Joshua Safer  is the executive director of the Mount Sinai Center for Transgender Medicine and Surgery in New York. He is the founding medical director of the Center for Transgender Medicine and Surgery at Boston University School of Medicine, and he was the inaugural president of the United States Professional Association for Transgender Health (USPATH).  He serves on the Global Education Initiative for the World Professional Association for Transgender Health (WPATH). Dr. Safer was a co-author of the Endocrine Society Guidelines for the medical care of transgender patients. This episode is part of a series on trans rights. The inspiration for these interviews is three bills currently moving through the Alaska State House: HB 183 which bans trans girls from playing girls sports; HB 105 which requires kids to get signed permission slips approving their preferred name and pronouns; and HB 338 which allows doctors to be sued up to 20 years after performing gender affirming procedures on trans youth.Alaska has many big problems. The pressing need to increase the funding of our public school system and finding a solution for an imminent energy crisis, for example. But instead of working on these very real, very substantial problems, we are spending the last weeks of session debating whether trans youth exist and have rights. They do exist; they do have rights.

Join us on a journey to uncover the secrets of longevity in this thought-provoking episode. Delving into the realm of supplements and hormones, we seek out to find if there are any strategies to enhance vitality and promote healthy aging. Coach Vinny takes the back seat as Dr. Eryn discusses the latest research and insights on potential interventions, from growth hormone to cortisol management to protein intake. Discover the truth about popular trends like NMN and NAD+ supplementation, as we separate fact from fiction. Learn about the role of testosterone, vitamin D, cocoa extract, and protein in promoting resilience and vitality as we age. Gain valuable insights into evidence-based approaches to longevity, empowering you to make informed choices for a vibrant, fulfilling life. Don't miss out on this essential guide to cracking the code on longevity and unlocking the potential for a healthier, happier future! PMIDs Cocoa Study – PMID: 35294962 Endocrine Society – PMID: 37326526 Coach Vinny Email: vinny@balancedbodies.io Instagram: vinnyrusso_balancedbodies Facebook: Vinny Russo Dr. Eryn Email: dr.eryn@balancedbodies.io Instagram: dr.eryn_balancedbodies Facebook: Eryn Stansfield LEGION 20% OFF CODE Go to https://legionathletics.com/ and use the code RUSSO for 20% off your order!

The Spanish Endocrine Conference was organized late last year by the "Sociedad Española de Endocrinologia y Nutricion (SEEN). SEEN offers an excellent resource for information to the Spanish-speaking world. Spain and Spanish-speaking countries have been our focus as we seek to develop more content in Spanish for our edition of Pituitary Word New in Español. Today's podcasts covers part of the conference and shares my conversations with three world-renowned Spanish endocrinologists. Don't miss my chat with Dr. Elena Valassi on how Cushing's and acromegaly affect bones and muscles. Dr. Manel Puig Domingo talks about his views on the new nomenclature or terminology between adenomas and neuroendocrine tumors (PitNets), a thorny issues we've been covering from all angles. He also gives us an update on his projects on facial recognition in acromegaly;  a fascinating subject since it could have a considerable impact on the early diagnosis of acromegaly. Lastly, I chatted with my good friend Dr. Javier Salvador, who recently retired from clinical work after almost 50 years as one of Spain's leading endocrinologists and professors at the University of Navarra. We chatted about endocrine education, awareness, technology, early diagnosis, and his new assignment teaching medical ethics. I hope this podcast will give you a new perspective from these leading researchers and physicians tackling these challenging diseases.

SERGE A. JABBOUR, MD, FACP, FACE is a Professor of Medicine and the Director of the Division of Endocrinology, Diabetes, and Metabolic Diseases at Jefferson. He is also the Director of the Jefferson Diabetes Center. Dr Jabbour completed his training in Endocrinology, Diabetes, and Metabolic Diseases at Thomas Jefferson University in Philadelphia.Dr Jabbour has been recognized with many honors and he is holder of many teaching awards. Dr Jabbour was named Top Doc in Philadelphia area every year since 2011 by Philadelphia Magazine and one of the best endocrinologists in the nation by Castle Connolly every year since 2012. Dr Jabbour is a member of numerous professional organizations, including The Endocrine Society, American Diabetes Association and American Association of Clinical Endocrinologists.Dr Jabbour has published many articles and chapters on diabetes, metabolic syndrome, various endocrine topics; he serves on the Editorial Board of many journals and he just finished in September 2021 his 5-year tenure as the Chair of the Endocrine Board Review Committee for The Endocrine Society.Dr Jabbour's main research interest is in the field of diabetes. He is involved in many clinical research trials related to new diabetes drugs. He also gives many lectures all over the world on different endocrine topics, mainly diabetes, either in the setting of grand rounds, symposia or other CME presentations. I am truly honored to have such an inspiring and world-class endocrinologist with me today. Welcome Dr. Jabbour, let's see how many people we can convince to do endocrinology.Jefferson Endocrinology:https://www.jeffersonhealth.org/clinical-specialties/endocrinology-diabetes-metabolic-diseases?gclid=CjwKCAjwiOCgBhAgEiwAjv5whBW4FTPRCa_lVxnQI577rjIie4qMEkxca7tNsBwTxndwYCamtYfiMBoCknsQAvD_BwEJefferson Diabetes Center:https://www.jeffersonhealth.org/clinical-specialties/diabetes-center___0:00 - Intro1:49 - Statistics About Endocrinology3:10 - What Is Endocrinology?5:22 - Journey Into Medicine and Endocrinology13:07 - Keeping the Team Happy15:42 - An Average Day/Week of an Endocrinologist19:40 - Advice for People Looking Into Leveling up Ranks22:50 - If I Give You $100 Million, What Would You Do?25:25 - Best Thing About Being an Endocrinologist27:35 - Making a Rare Diagnosis32:16 - Passion for Studying Diabetes34:21 - Things We Should Know About Type 2 & 1 Diabetes53:06 - What Do You Think About Ozempic and Glp-1?59:44 - Dietary Tips1:06:21 - Hemoglobin a1c Levels1:20:10 - SGLT2 Inhibitors1:16:48 - Future of Endocrinology1:19:34 - Changes Over the Years1:20:17 - Myths About Diabetes1:24:29 - High Number of Diabetic Patients in the U.S.1:30:39 - Advice to People Looking Into Endocrinology1:32:36 - Maximizing Competitiveness Going Into Endocrinology1:39:00 - What Makes the Best-Med Students/Residents/Fellows?1:42:28 - Advice to People Entering a Career in Medicine1:45:17 - What Advice Would You Give Your 18-Year-Old Self?1:48:20 - Adapting to the U.S.1:49:43 - Closing Message1:51:57 - Outro__ResourcesWho Moved My Cheese? by Dr Spencer Johnson: https://amzn.eu/d/dZHrYY8 ___View the Show Notes Page for This Episode for transcript and more information: zhighley.com/podcast___Connect With ZachMain YouTube: @ZachHighley Newsletter: https://zhighley.com/newsletter/Instagram: https://www.instagram.com/zachhighley/?hl=enWebsite: https://zhighley.comTwitter: https://twitter.com/zachhighleyLinkedln: https://www.linkedin.com/in/zach-highley-gergel-44763766/Business Inquiries: zachhighley@nebula.tv___Listen for FreeSpotify: https://open.spotify.com/show/23TvJdEBAJuW5WY1QHEc6A?si=cf65ae0abbaf46a4Apple Podcast: https://podcasts.apple.com/us/podcast/the-zach-highley-show/id1666374777___Welcome to the Zach Highley Show, where we discuss personal growth and medicine to figure out how to improve our lives. My name is Zach a Resident Physician in Boston. Throughout these episodes I'll interview top performers from around the world in business, life, and medicine in hopes of extracting the resources and techniques they use to get to the top.The best way to help the show is share episodes on any platform. If you think a friend or family member will like a certain episode, send it to them!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In the last few years, the credibility of science or, more accurately, scientists, has taken more than a few hits. Take for instance the rush by many doctors, researchers, academics, and medical institutions to force transgender ideology on children. For example, the American Academy of Pediatrics and the Endocrine Society have both issued guidelines for medically transitioning minors. From the beginning, maverick scientists have called foul, pointing out that the safety and long-term effectiveness of such “treatments” had not been evaluated. It seems now that only real-world consequences for actual children can curb the enthusiasm for untested and misguided experimentation on kids.   In 2022, the U.K.'s largest gender clinic announced its closure over a lack of evidence to support its ghoulish interventions. Shortly afterward, U.K. lawyer Tom Goodhead estimated that around 1,000 families would join in legal action against the clinic, claiming their children were “misdiagnosed and rushed into transitioning.” The first lawsuits against the American Academy of Pediatrics have also been filed by a child who grew up and regretted transitioning.   Transgender “medicine” isn't the only practice advanced as “scientifically proven” despite the absence of evidence. Even earlier, assisted reproductive technologies like in vitro fertilization and surrogacy were pushed on the public with little understanding of or concern for the safety and long-term consequences for women and children. Like transgender medicine, the line is that the “science says the kids will be fine.” Don't buy it.   Recently, the Heritage Foundation's Emma Waters reviewed the available evidence about some of these technologies. “Despite what many experts want you to believe,” she writes, “we actually know very little about the impact of surrogacy on the long-term wellbeing of children and families.” As it turns out, babies gestated by a surrogate show a marked increase in preterm births, physical defects, and low weight. This is just what we know for certain, partly because we've been kept in the dark.   As Waters explains, scholars who review the literature on surrogacy typically use studies that are outdated, small, short-term, or based on self-reporting by the “parents” who paid for the children. A frequently cited U.K. study “relied on the parents' own assessment of the child's wellbeing, not objective outcomes or the child him/herself.” Using that study as proof that surrogacy doesn't harm children is kind of like asking students to grade their own exams.  Waters suggests two major red flags about the current research: first, studies in which “the conclusions are too squeaky clean;” and second, studies whose “self acknowledged goal” is “showing that there are no differences between same-sex, natural, and artificially conceived families and the impact … on children.” In other words, these studies are advocacy, not science.   Constructing better studies, Waters argues, will require tracking children over longer periods, having surrogates report their number of pregnancies, keeping tabs on who sells or donates eggs and sperm, and knowing who children born of surrogates are and who their biological parents are. As she warns, “There is a huge difference between ‘no harms' and no *known* harms.”  Still, even without that research, there are pragmatic and moral reasons to oppose the creation of children with the intent to implant them or place them with strangers. Children were designed to know their parents. Separation from the man and woman who made them is a tragedy. Arrangements like foster care and adoption respond to that tragedy, but conceiving children with the express purpose of separating them from their parents is very different. It creates the tragedy.   Similarly, paying women to carry children for nine months and then forcing them to walk away as part of a commercial transaction ignores the intimacy and sanctity of that bond, as well as its ongoing, powerful effects on both carrier and baby.      Pope Francis was recently crystal clear on this one, despite his confusing and misleading statements on other serious issues. In a recent speech to diplomats, he blasted surrogacy as “deplorable,” insisting it “represents a grave violation of the dignity of the woman and the child,” whom it turns into “an object of trafficking.” “A child,” he added, “is always a gift and never the basis of a commercial contract.”  In this age of accelerating technology, and ideologues eager to wield it, the most vulnerable members of society need someone to hold so-called “experts” accountable and to ask the questions about human design, purpose, rights, and relationships that no study can answer. No matter how scientific sounding they are, claims that we can ignore God's design for sex and the family are expressions of an anti-human worldview, not objective research. And that's a very good reason to say “no” to this worldview's ongoing demand for tiny test subjects.   This Breakpoint was co-authored by Shane Morris. For more resources to live like a Christian in this cultural moment, go to breakpoint.org.  _______ Don't Follow Your Heart is an incredibly important book that will help you unlock the lies behind each of the cultural lies of self-worship while also encouraging you to live with courageous faith for Christ in this cultural moment. Request your copy by giving a gift of any amount to the Colson Center this month! 

On this episode, toxicology scientist Dr. Jane Muncke joins Nate to discuss the current state of food production and the effects of ultra processed foods and their packaging on our health. Over the last century processed food has taken over our supermarkets and our diets, and at the same time the containers they're sold in have evolved as well - to be more eye-catching and keep food ‘good' for longer. But what have we sacrificed in exchange for efficiency, ease, and convenience? How do the chemicals used in packaging and processing transfer into the food we eat and subsequently end up in our bodies? Will switching away from these toxic food practices require more local food supply chains - and correspondingly simpler diets and lifestyles? About Jane Muncke Jane Muncke holds a doctorate degree in environmental toxicology and a MSc in environmental science from the ETH Zurich. Since 2012 she has been working as Managing Director and Chief Scientific Officer at the charitable Food Packaging Forum Foundation (FPF) in Zurich, Switzerland. FPF is a research and science communication organization focusing on chemicals in all types of food contact materials. She is a full scientific member of the Society of Toxicology (SOT), the Society for Environmental Chemistry and Toxicology (SETAC), the American Chemical Society (ACS) and the Endocrine Society. Since 2019, she has been an elected expert member of the Swiss Organic Farming Association Bio Suisse's committee on trade and processing where she contributes to further developing the standards for processing and packaging of organic food. She is a director of the FAN initiative, a collective of experts warning about resource overshoot, the polycrisis, and related societal collapse. Watch on YouTube: https://youtu.be/I2-roqSWjFo  More info, and show notes: https://www.thegreatsimplification.com/episode/104-jane-muncke 

The ALL ME® Podcast Human Growth Hormone (HGH) – Does it work? – Dr. Brad Anawalt / Dr. Andy Hoofnagle The ALL ME Podcast is working hard to provide you with information from the World's leading experts when it comes to all things Appearance and Performance Enhancing Substance related.   Throughout the year we ask our listeners to send us topics they'd like to learn more about.  Recently we've been getting asked a lot about Human Growth Hormone (HGH or GH).  Not only have people written in requesting more information on GH, we have had questions from students following our programs.  In order for us to have the best understanding of these drugs we have gone out and found multiple experts to interview on this topic.  In this podcast you're going to hear from two brilliant and highly respected Doctors and Researchers in their field. Dr. Brad Anawalt Bradley Anawalt, M.D., is UW Medical Center's chief of Medicine and a board certified physician at the Endocrine and Diabetes Care Center at UW Medical Center – Roosevelt and Fred Hutchinson Cancer Center. He is also vice chair of UW's Department of Medicine and a UW professor of General Internal Medicine. He has been selected on local and national lists of "Best Doctors." Dr. Anawalt is an hormone specialist whose clinical interests include thyroid disorders, osteoporosis, male infertility, low testosterone and other hormonal abnormalities. He enjoys answering patients' questions and addressing their concerns. Dr. Anawalt earned his M.D. at UC Davis. His primary research interests are focused on the effects of testosterone in men. He has published widely on this topic. He has served in leadership roles in the Endocrine Society and acts as a consultant for the United States Anti-Doping Agency. Dr. Andy Hoofnagle Andy Hoofnagle, M.D., Ph.D., is a board certified pathologist for Laboratory Medicine at UW Medical Center, head of Clinical Chemistry and a UW professor of Laboratory Medicine. Dr. Hoofnagle's lab uses mass spectrometry in the care of patients. In addition, they are currently investigating the role of high density lipoproteins in protecting patients with chronic kidney disease from atherosclerosis. It is his main goal to provide the most accurate testing for every patient in the UW Medicine healthcare system. He feels his talented medical laboratory scientists are in a league of their own. Dr. Hoofnagle earned his M.D. and Ph.D. from the University of Colorado. His clinical and research interests include clinical chemistry, mass spectrometry, proteomics, metabolomics, vitamin D and high density lipoproteins. Both of these gentlemen are going to take the topic of Human Growth Hormone and break it down to where you're able to understand what it is, why is prescribed and how it works.  There is a lot of misinformation out there on this topic and these guys do a great job of providing great information as well as debunking many of the HGH myths. Disclaimer The content in this podcast represents the opinion and knowledge of our guests. This podcast should not be used in any legal capacity whatsoever, including but not limited to establishing “standard of care” in a legal sense or as a basis for expert witness testimony.  No guarantee is given regarding the accuracy of any statements or opinions made on the podcast The content should not be taken as medical advice and is for information purposes only.  Should you have any medical questions please consult your healthcare professional. Resources and Links: Websites:  . What are the risks of HGH treatment? HGH treatment might cause a number of side effects for healthy adults, including: ·         Carpal tunnel syndrome ·         Increased insulin resistance ·         Type 2 diabetes ·         Swelling in the arms and legs (edema) ·         Joint and muscle pain ·         For men, enlargement of breast tissue (gynecomastia) ·         Increased risk of certain cancers Clinical studies of HGH treatment in healthy older adults have been relatively small and short in duration, so there's little to no information about the long-term effects of HGH treatment. Example of Acromegaly According to the Mayo Clinic: Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood. When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism. But in adulthood, a change in height doesn't occur. Instead, the increase in bone size is limited to the bones of your hands, feet and face, and is called acromegaly. Because acromegaly is uncommon and the physical changes occur slowly over many years, the condition sometimes takes a long time to recognize. Untreated, high levels of growth hormone can affect other parts of the body, in addition to your bones. This can lead to serious — sometimes even life-threatening — health problems. But treatment can reduce your risk of complications and significantly improve your symptoms, including the enlargement of your features. Follow Us: ·         Twitter:  @theTHF TikTok:  @theTHF10 ·         Instagram:  @theTHF ·         Facebook: Taylor Hooton Foundation ·         #ALLMEPEDFREE Contact Us:  Email:  Phone: 214-449-1990 ALL ME Assembly Programs:  

Endocrine Review Course Episode 17 Learning Objectives: - Describe the physiological mechanism counter regulating insulin induced hypoglycemia. - Describe 3 levels of hypoglycemia severity - Be aware of the recommendations published by the Endocrine Society on management of individuals at high risk for hypoglycemia

According to the National Institutes of Health, more than two in five adults have obesity in the United States, and nearly one in three is overweight. To equip health care practitioners with the resources they need to treat patients with obesity, the Endocrine Society recently held its innaugual obesity fellows program, an exclusive, application-based, educational activity for current fellows. The program covered a wealth of information, and host Aaron Lohr talks with Amy Rothberg, MD, DABOM, program chair and a clinical professor of internal medicine at the University of Michigan’s School of Public Health. If you weren’t able to attend the fellows program, we have a free series of on-demand lectures available online, and those are accredited. With thanks to Lilly USA LLC and Novo Nordisk for making both the obesity fellows program and this podcast episode possible through an unrestricted, educational grant. Show notes, including a link to the Endocrine Society Learning Center for earning ABIM points and AMA PRA Category 1 credits, are available at https://www.endocrine.org/podcast/enp81-obesity-fellows-program — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

According to the National Institutes of Health, more than two in five adults have obesity in the United States, and nearly one in three is overweight. To equip health care practitioners with the resources they need to treat patients with obesity, the Endocrine Society recently held its innaugual obesity fellows program, an exclusive, application-based, educational activity for current fellows. The program covered a wealth of information, and host Aaron Lohr talks with Amy Rothberg, MD, DABOM, program chair and a clinical professor of internal medicine at the University of Michigan’s School of Public Health. If you weren’t able to attend the fellows program, we have a free series of on-demand lectures available online, and those are accredited. With thanks to Lilly USA LLC and Novo Nordisk for making both the obesity fellows program and this podcast episode possible through an unrestricted, educational grant. Show notes, including a link to the Endocrine Society Learning Center for earning ABIM points and AMA PRA Category 1 credits, are available at https://www.endocrine.org/podcast/enp81-obesity-fellows-program — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

According to the National Institutes of Health, more than two in five adults have obesity in the United States, and nearly one in three is overweight. To equip health care practitioners with the resources they need to treat patients with obesity, the Endocrine Society recently held its innaugual obesity fellows program, an exclusive, application-based, educational activity for current fellows. The program covered a wealth of information, and host Aaron Lohr talks with Amy Rothberg, MD, DABOM, program chair and a clinical professor of internal medicine at the University of Michigan’s School of Public Health. If you weren’t able to attend the fellows program, we have a free series of on-demand lectures available online, and those are accredited. With thanks to Lilly USA LLC and Novo Nordisk for making both the obesity fellows program and this podcast episode possible through an unrestricted, educational grant. Show notes, including a link to the Endocrine Society Learning Center for earning ABIM points and AMA PRA Category 1 credits, are available at https://www.endocrine.org/podcast/enp81-obesity-fellows-program — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

In this episode, Greg and Lyndsey sit down for a discussion about cortisol with Beth Skwarecki, the senior health editor at Lifehacker. The dangers of high cortisol are a persistent topic of content on social media content, so the discussion focuses on the types of claims that are being made, the dubious methods of self-diagnosis and “treatment” being recommended, and the potential risks and dangers associated with letting social media convince you that you're basically an endocrinologist.You can read Beth's article on this topic here: TikTok Myth of the Week: All Your Problems Are Due to High Cortisol TIME STAMPS What is cortisol? (00:02:52)Epinephrine vs. AdrenalineBasic cortisol physiologyLow cortisol and adrenal crisis 'Normal' cortisol levels (00:18:44)Reference range for normal cortisolVariability in cortisol awakening responseCortisol awakening response poorly associated with total daily cortisol AUCEarly childhood stress (with family income as a proxy) associated with either elevated or depressed cortisol awakening responseCortisol discourse on TikTok (00:33:56)Representative examples of TikTok cortisol content:https://www.tiktok.com/@brittwd/video/7263934911432707374?_r=1&_t=8gQo2Q04An4https://www.tiktok.com/@mallorymh/video/7242431357446556970https://www.tiktok.com/@xomgitsbunnie/video/7272557452095376686https://www.tiktok.com/@liv.ingwell/video/7263106370696695083Cortisol vs other social media trends (00:47:48)The Endocrine Society on adrenal fatigueRepresentative examples of TikTok adrenal fatigue content: https://www.tiktok.com/@clairethenutritionist/video/6964559576985308421?_r=1&_t=8gY2Pf0iBPnhttps://www.tiktok.com/@begreatwithnate/video/7191220532862356778?_r=1&_t=8gY2YIPYDDGhttps://www.tiktok.com/@ambitiousandcaffeinated/video/7201977016571202821?_r=1&_t=8gY2fS0vaRPhttps://www.tiktok.com/@ghallfitness/video/7190694428586151170?_r=1&_t=8gY2uaAaGvShttps://www.tiktok.com/@thewellnesswaylargo/video/7254966223329398058?_t=8gY34NUrjRO&_r=1Cortisol and menstruation (01:07:41)Cortisol and trauma (01:11:32)Representative example of movements claimed to reduce cortisol associated with traumaTapping: https://www.thetappingsolution.com/Cortisol and exercise (01:15:55)Cortisol and overtraining (most notably, Figure 3)Impact of exercise intensity on cortisol responseCortisol levels return to normal very soon after exercise endsHackney review on exercise and cortisolSpecific claims about high cortisol (01:38:30)Cortisol, caffeine and sleep (01:45:39)Plenty of things cause you to wake up at nightSpiritual meaning of waking up at 3AMCaffeine and cortisolCaffeine's effects on cortisol are attenuated within 5 days of consumptionCoffee intake is associated with plenty of positive health outcomes (hard to square with the idea that caffeine spikes cortisol in a manner that's deleterious to your health)Real ways to regulate cortisol (01:55:49)Self-diagnosis (02:03:08)Cortisol disorders can cause real disease (story Beth referenced about woman with tumor)Other things that can cause Cushing-like symptomsTakeaways (02:08:13)Where to find BethCheck out Beth's writing on LifehackerBeth's 510 Dinnie DeadliftBeth's books: Outbreak! and Genetics 101Follow Beth on Twitter Recommended products and more from the SBS team Work with a Stronger By Science coach: Get personalized training and nutrition plans and ongoing support from one of our expert coaches.Try MacroFactor for free: Use code SBS to get a 14-day free trial of our nutrition app MacroFactor. MacroFactor has the fastest food logger on the market and its smart nutrition coach adapts to your metabolism to keep you on track with your goals. Download it today on the App Store or Google Play.Join the Research Spotlight newsletter: Our newsletter is the easiest way to stay up to date with the latest exercise and nutrition science.Join the SBS Facebook group and Subreddit.BulkSupplements: Next time you stock up on supplements, be sure to use the promo code “SBSPOD” (all caps) to get 5% off your entire order.MASS Research Review: Subscribe to the MASS Research Review to get concise and applicable breakdowns of the latest strength, physique, and nutrition research – delivered monthly.Send your Q&A questions to podcast@strongerbyscience.com

Today’s topic is type 1 diabetes. What are some of the biggest challenges facing us today when it comes to diagnosing and treating type 1 diabetes, and how can we meet those challenges? Host Aaron Lohr talks with Irl Hirsch, MD, from the UW Diabetes Institute at the University of Washington. Dr. Hirsch and Davida Kruger, NP, from Henry Ford Health in Detroit co-chaired the Endocrine Society’s type 1 diabetes fellows series. That program and this podcast episode were both made possible by unrestricted, educational grants from Abbott Diabetes Care Inc., CeQur Corp., Dexcom, Insulet, JDRF, Lilly USA LLC, MannKind Corp., Novo Nordisk, Prevention Bio, Vertex, and Tandem Diabetes Care. Show notes are available at https://www.endocrine.org/podcast/enp79-type-1-diabetes-update — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Today’s topic is type 1 diabetes. What are some of the biggest challenges facing us today when it comes to diagnosing and treating type 1 diabetes, and how can we meet those challenges? Host Aaron Lohr talks with Irl Hirsch, MD, from the UW Diabetes Institute at the University of Washington. Dr. Hirsch and Davida Kruger, NP, from Henry Ford Health in Detroit co-chaired the Endocrine Society’s type 1 diabetes fellows series. That program and this podcast episode were both made possible by unrestricted, educational grants from Abbott Diabetes Care Inc., CeQur Corp., Dexcom, Insulet, JDRF, Lilly USA LLC, MannKind Corp., Novo Nordisk, Prevention Bio, Vertex, and Tandem Diabetes Care. For helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Today’s topic is type 1 diabetes. What are some of the biggest challenges facing us today when it comes to diagnosing and treating type 1 diabetes, and how can we meet those challenges? Host Aaron Lohr talks with Irl Hirsch, MD, from the UW Diabetes Institute at the University of Washington. Dr. Hirsch and Davida Kruger, NP, from Henry Ford Health in Detroit co-chaired the Endocrine Society’s type 1 diabetes fellows series. That program and this podcast episode were both made possible by unrestricted, educational grants from Abbott Diabetes Care Inc., CeQur Corp., Dexcom, Insulet, JDRF, Lilly USA LLC, MannKind Corp., Novo Nordisk, Prevention Bio, Vertex, and Tandem Diabetes Care. Show notes are available at https://www.endocrine.org/podcast/enp79-type-1-diabetes-update — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

This Week In Wellness research from the Journal of the Endocrine Society has shown that the ketogenic (or keto) diet may lower testosterone levels in women with polycystic ovary syndrome (PCOS), potentially influencing their fertility. https://www.sciencedaily.com/releases/2023/09/230907105759.htm https://academic.oup.com/jes/article/7/10/bvad112/7259972 The post TWIW 213: Keto diets may help women with PCOS conceive first appeared on The Wellness Couch.

In today's episode, Julia talks with Dr. Aimee, a renowned fertility specialist recognized as the "egg whisperer."  Together, Julia and Dr. Aimee delve into her complete “obsession to bring more love into this world” by helping more intended parents conceive.  They also discuss the many ways she is changing the patient experience by shifting the mindset around fertility treatment - from one of a battle to one of glitter, hope, and magic.    Dr. Aimee distinguishes her approach to in vitro fertilization (IVF) from that of her peers, emphasizing her focus on "OLS (Ovarian Life Support)" and her unwavering dedication to retrieving every viable egg from her patients. While she exudes enthusiasm for IVF, Dr. Aimee remains pragmatic, acknowledging that not every woman will achieve pregnancy, and she candidly reveals how she navigates such circumstances. Don't miss this captivating two-part series.   IN THIS EPISODE:   [02:48] Dr. Aimee shares her love of being a fertility doctor, knowing that was her calling from an early age [05:05] Why is she called ‘the egg whisperer' and getting through the hard stuff [10:15] Dr. Aimee's advice to someone who is discouraged. Who is her typical patient [13:24] How her process is different than other specialists and how she is committed to treating women in all 50 states [21:55] How she advises someone who loses a baby  [25:55] Dealing with the cost of IVF and Dr. Aimee's hope for the future [30:30] Dr. Aimee encourages patients to know their medical history and the procedures they have had to prevent mistakes  [33:28] Dr. Aimee defines family   KEY TAKEAWAYS:   Dr. Aimee provides online IVF classes available to anyone. They are similar to getting a full consultation. Learn about IVF. Remember your treatment history. Don't expect every doctor to remember the details about your medical treatments. Be your advocate.  After many treatments and discouragements trying to get pregnant, you might need to stop and take a break to see if going through more treatment is right for you. Be realistic.    RESOURCE LINKS:   Stork'd - Facebook   Stork'd - Instagram   Stork'd - YouTube    Dr. Aimee - Facebook   Dr. Aimee - Website   Egg Whisperer - Instagram   Egg Whisperer School - Website   BIO Dr. Aimee graduated from UCLA School of Medicine and completed her residency in Obstetrics & Gynecology at Harvard Medical School. She also completed a fellowship in Reproductive Endocrinology & Infertility and holds a Master's in Public Health Management and Policy from the University of Michigan.   She has presented her research at the national meetings of the American Society of Reproductive Medicine, The Endocrine Society and The American College of Obstetricians and Gynecologists. Her research has been published in several journals, including Fertility and Sterility, The Journal of Clinical Endocrinology and Metabolism, Obstetrics and Gynecology and Menopause. She is a fellow of the American College of Obstetrics and Gynecology and continues to contribute to research in the field of reproductive endocrinology and infertility. She has co-authored book chapters on ultrasonography and male infertility with national leaders in the field of reproductive endocrinology.   In her off-time, Dr. Aimee is a mom to four rambunctious kids aged ten and under. You can email her directly at email@draimee.org

Host Aaron Lohr went to Chicago in June to interview researchers presenting at the Endocrine Society’s annual meeting, ENDO 2023. Here he talks with Julie Hens, PhD, from Yale University about her team’s research, titled “Protective Effects of Lactation on Maternal Metabolism.” After that interview, listen to a sneak peek of our other, members-only podcast, Endocrine Feedback Loop, an episode from November 2022 about changes in glucose throughout the menstrual cycle in type 1 diabetes. For helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Host Aaron Lohr went to Chicago in June to interview researchers presenting at the Endocrine Society’s annual meeting, ENDO 2023. Here he talks with Julie Hens, PhD, from Yale University about her team’s research, titled “Protective Effects of Lactation on Maternal Metabolism.” After that interview, listen to a sneak peek of our other, members-only podcast, Endocrine Feedback Loop, an episode from November 2022 about changes in glucose throughout the menstrual cycle in type 1 diabetes. Show notes are available at https://www.endocrine.org/podcast/enp71-lactation-and-maternal-metabolism — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Host Aaron Lohr went to Chicago in June to interview researchers presenting at the Endocrine Society’s annual meeting, ENDO 2023. Here he talks with Julie Hens, PhD, from Yale University about her team’s research, titled “Protective Effects of Lactation on Maternal Metabolism.” After that interview, listen to a sneak peek of our other, members-only podcast, Endocrine Feedback Loop, an episode from November 2022 about changes in glucose throughout the menstrual cycle in type 1 diabetes. Show notes are available at https://www.endocrine.org/podcast/enp71-lactation-and-maternal-metabolism — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

A Catholic school wins in court on hiring, The Endocrine Society makes dangerous claims, "chest feeding" - another crazy idea from the equity movement, the House passes the military spending bill with tenacity and how we can refocus America to help our children. We cover these important stories while being reminded that God is in control.

Whether we like it or not, we’re all getting older. What do we know about how aging impacts our endocrine system? What don’t we know? That’s what we’re here to talk about today, as we look at the new scientific statement from the Endocrine Society titled, “Hormones and Aging: An Endocrine Society Scientific Statement.” Host Aaron Lohr talks with one of the statement’s authors, Anne Cappola, MD, a professor of medicine at the University of Pennsylvania and founding director of Penn Medical Communication Research Institute. Show notes are available at https://www.endocrine.org/podcast/enp70-hormones-and-aging — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

In this 145th in a series of live discussions with Bret Weinstein and Heather Heying (both PhDs in Biology), we discuss the state of the world through an evolutionary lens.This week, we begin by discussing the interview between Jon Stewart and the Attorney General of Arkansas. Yes, protecting children does mean overriding the recommendations of several prominent organizations, including the American Medical Association (AMA), and the Endocrine Society, both of which we discuss as well. The President of the AMA says he's working hard against medical disinformation, in part by participating in a “Festival of Fact-Checking” sponsored by self-appointed fact-checking organizations, and featuring science himself, Anthony Fauci. Then, with help from Barbara Ehrenreich's excellent book on the topic, we discuss actual festivals, and the human history of ecstatic ritual, and ask whether an increase in depression coincided in human history with a decline in festivals. Finally, we discuss the virtues of driving around with your windows open.*****Our sponsors:ReliefBand: Get relief from nausea without drugs. Go to https://www.reliefband.com, use code DARKHORSE, and you'll receive 20% off plus free shipping.LMNT: Electrolyte drink mix with all the good salts, and none of the bad stuff. Free sample pack of all 8 flavors with any purchase at https://DrinkLMNT.com/DARKHORSE.Allform: Get 20% off any order (of a beautiful sofa) from Allform at https://allform.com/darkhorse.*****Our book, A Hunter-Gatherer's Guide to the 21st Century, is available everywhere books are sold, and signed copies are available here: https://darvillsbookstore.indielite.orgCheck out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.orgHeather's newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.comFind more from us on Bret's website (https://bretweinstein.net) or Heather's website (http://heatherheying.com).Become a member of the DarkHorse LiveStreams, and get access to an additional Q&A livestream every month. Join at Heather's Patreon.Like this content? Subscribe to the channel, like this video, follow us on twitter (@BretWeinstein, @HeatherEHeying), and consider helping us out by contributing to either of our Patreons or Bret's Paypal.Looking for clips from #DarkHorseLivestreams? Check out our other channel:  https://www.youtube.com/channel/UCAWCKUrmvK5F_ynBY_CMlIATheme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.*****Q&A Link: https://youtu.be/Gk-T5PfOnX0Mentioned in this episode:Jon Stewart interviews the Attorney General of Arkansas: https://twitter.com/TheProblem/status/1578414849083654144What Do Girls Do? https://naturalselections.substack.com/p/whatdogirlsdo?r=83qgf&utm_campaign=post&utm_medium=webThe Endocrine Society's 2017 Gender Dysphoria/Gender Incongruence Guideline Resources: https://www.endocrine.org/clinical-practice-guidelines/gender-dysphoria-gender-incongruence“Turning the tide against medical disinformation will take all of us” from the President of the American Medical Association: https://www.ama-assn.org/about/leadership/turning-tide-against-medical-disinformation-will-take-all-usUnited Facts of America: A Festival of Fact-Checking: https://www.poynter.org/event/united-facts-of-america-a-festival-of-fact-checking/Dancing in the Streets: A History of Collective Joy, 2006 book by Barbara Ehrenreich: https://www.amazon.com/Barbara-Ehrenreich/e/B000AQ4X9S/Support the show