Podcast appearances and mentions of stephan guyenet

การกินถูกควบคุมอัตโนมัติ (แต่เรามักจะไม่เชื่อกันว่า เวลาเราสั่งผัดกะเพราเนื้อริบอายจากร้านนี้นั้น สมองส่วน hypothalamus เป็นผู้สั่ง เพราะมันคือ option generator ที่อยู่ตำแหน่งบนสุด เราไม่ได้สั่งมาจาก conscious brain) เหมือนความดันโลหิต ระดับน้ำตาลในเลือด อุณหภูมิร่างกาย มีระบบ feedback control ที่แน่นหนา เราจึงพบว่าการลดน้ำหนักที่ดูเหมือนง่าย เพราะก็แค่ควบคุมการกินเข้าให้เท่ากับการใช้ออกไป แต่กลับไม่ง่ายเพราะCalories in & Calories out are not independent มีระบบควบคุมน้ำหนักอยู่ที่ hypothalamus คอยปรับสมดุล CI และ CO อยู่เสมอ มีงานวิจัยสำคัญชื่อ Long-Term Persistence of Hormonal Adaptations to Weight Loss ตีพิมพ์ใน NEJM ในปี 2554 ที่อธิบาย biological feedback เมื่อเราลดน้ำหนัก ผ่านฮอร์โมนหิวและอิ่ม leptin เพื่อพาร่างกลับไปที่จุดตั้งค่าน้ำหนักเดิมตอนที่เราอ้วน เมื่อเราลดน้ำหนักไปสักพัก เราจะถึงจุดที่เรียกว่า weight plateau ลดน้ำหนักต่อไปไม่ได้อีกแล้ว และน้ำหนักกำลังจะคืบคลานกลับไปที่จุดตั้งค่าน้ำหนักเดิมตอนอ้วน นั่นหมายถึงผู้ที่ลดน้ำหนักกำลังต่อสู้กับ “Biology” ของตัวเอง ซึ่ง Dr.Stephan Guyenet ผู้เขียนหนังสือชื่อ “The Hungry Brain” กล่าวว่า “Biology always wins”

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 2809: Stephan Guyenet offers an insider's perspective on the US News & World Report diet rankings, shedding light on their methodology and limitations. His reflections highlight the complexity of assessing diets, emphasizing the value of scientific evidence while questioning how public perceptions influence health guidelines. Read along with the original article(s) here: https://www.stephanguyenet.com/reflections-on-the-us-news-world-report-diet-rankings-and-my-involvement-in-them/ Quotes to ponder: "The US News diet rankings are an attempt to provide guidance in a field overflowing with conflicting claims and misinformation." "Ranking diets is inherently challenging because it involves weighing diverse goals, from health optimization to environmental sustainability." "Science should serve as a guidepost, but it must be interpreted through the lens of individual and societal priorities." Episode references: The Hungry Brain by Stephan Guyenet: https://www.amazon.com/Hungry-Brain-Outsmarting-Instincts-Overeat/dp/125008119X Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 2809: Stephan Guyenet offers an insider's perspective on the US News & World Report diet rankings, shedding light on their methodology and limitations. His reflections highlight the complexity of assessing diets, emphasizing the value of scientific evidence while questioning how public perceptions influence health guidelines. Read along with the original article(s) here: https://www.stephanguyenet.com/reflections-on-the-us-news-world-report-diet-rankings-and-my-involvement-in-them/ Quotes to ponder: "The US News diet rankings are an attempt to provide guidance in a field overflowing with conflicting claims and misinformation." "Ranking diets is inherently challenging because it involves weighing diverse goals, from health optimization to environmental sustainability." "Science should serve as a guidepost, but it must be interpreted through the lens of individual and societal priorities." Episode references: The Hungry Brain by Stephan Guyenet: https://www.amazon.com/Hungry-Brain-Outsmarting-Instincts-Overeat/dp/125008119X Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 2808: Dr. Stephan Guyenet shares his insights into the U.S. News & World Report Diet Rankings, explaining the scientific rigor behind the rankings and his role in evaluating diets for health and sustainability. He also discusses misconceptions about certain diets and offers a balanced perspective on the complexity of nutrition science. Read along with the original article(s) here: https://www.stephanguyenet.com/reflections-on-the-us-news-world-report-diet-rankings-and-my-involvement-in-them/ Quotes to ponder: "The ideal diet is the one that you can follow long-term while meeting your nutritional needs and supporting your health." "It's important to consider not only health outcomes but also the practical challenges people face in adopting specific diets." Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 2808: Dr. Stephan Guyenet shares his insights into the U.S. News & World Report Diet Rankings, explaining the scientific rigor behind the rankings and his role in evaluating diets for health and sustainability. He also discusses misconceptions about certain diets and offers a balanced perspective on the complexity of nutrition science. Read along with the original article(s) here: https://www.stephanguyenet.com/reflections-on-the-us-news-world-report-diet-rankings-and-my-involvement-in-them/ Quotes to ponder: "The ideal diet is the one that you can follow long-term while meeting your nutritional needs and supporting your health." "It's important to consider not only health outcomes but also the practical challenges people face in adopting specific diets." Learn more about your ad choices. Visit megaphone.fm/adchoices

Can we really blame our genes for weight gain, or is there more to the story? In this episode, Ted sits down with obesity expert Stephan Guyenet to uncover the science behind fat gain. They dive into how genetics, environment, and everyday habits shape your body—and what you can do to take control. Listen now!

This is an “ask me anything” (AMA) episode with Dr. Stephan Guyenet, an expert in obesity neuroscience and eating behavior. This episode was originally published on Sigma Nutrition Premium. If you're interested in subscribing to Sigma Nutrition Premium, then check all the details here. Questions Answered: [04.27] If we surgically remove adipose tissue, do leptin levels suddenly drop? How would this impact hunger over time? [06.56] How does chronic energy restriction (or following a crash diet) affect long-term appetite regulation? [13.21] How do anorexia and pronounced obesity defy the rules of metabolic compensation? [24.12] Why do some SDRIs (serotonin–dopamine reuptake inhibitors) reduce hunger/appetite? [28.02] Can an algorithm really decipher someone's “ideal weight? [33.08] Could the “brain microbiome” impact appetite regulation and/or obesity? [35.34] In our current environment, are the only efficacious interventions drugs and bariatric surgery? [46.01] What should we make of claims by Gary Taubes about insulinogenic foods? [52.37] Is there a maximum duration someone should spend in fat loss (or weight gain) phases? [53.43] Why do some people struggle to gain weight? Links: Join our newsletter Subscribe to Premium View our recommended resources

Are you frustrated by the stubborn body fat that won't come off despite all your efforts? Do you ever wonder if it's all due to lack of discipline, or could there be a deeper reason? And how much do your genetics actually play a role in your fat loss journey?Philip (@witsandweights) dives into the fascinating world of neuroscience and body composition with special guest Dr. Stephan Guyenet, a neuroscientist, obesity researcher, and author of The Hungry Brain. They explore the science behind why some people struggle more than others to lose weight and how genetics might be the hidden force shaping your body fat levels. Dr. Guyenet also breaks down how the brain's reward system influences your cravings and reveals how minor tweaks to your environment and habits can make a huge difference in your fat loss efforts.Dr. Stephan Guyenet has spent over a decade studying the neuroscience of obesity. With a PhD in neuroscience, his work focuses on the brain's role in regulating body fat and how our modern environment contributes to weight gain. He is also the founder of Red Pen Reviews, which provides scientific accuracy scores for popular health and nutrition books.

EP 480 Audio Show Notes Welcome to the Mind Muscle Connection Podcast!In this episode, we welcome back Dr. Stephan Guyenet, author of "The Hungry Brain," to discuss the updates he would make on his book.Dr. Stephan shares insights on how your understanding of exercise's role in weight loss has evolved, challenging traditional views on energy balance and genetic factors influencing your body body weight. Also, recent researches that have supported and slightly altered some of the ideas presented in his book and more.If you're struggling with weight issues or simply curious about Dr Stephan's book, be sure to tune in!Let's talk about:Introduction about Dr. Stephan GuyenetUpdates on Dr. StephanGenetics and Energy BalanceResting metabolic rateRecommendationsEnergy expenditureWhy physically inactive people's appetite is dysregulatedDiet & exerciseUpdates he would make to his bookWhere to find Dr. StephanDr. Stephan's Twitter: @sguyenetFollow me on Instagram for more information and education:  @jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Masterclass: HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HERE

In this episode, I'm re-releasing an episode with Dr. Stephan Guyenet and Dr. Mario Kratz, two impressively experienced nutrition researchers with a wide range of expertise, about their organization Red Pen Reviews, a non-profit dedicated to publishing unbiased, scientifically accurate reviews for current nutrition books hitting the market. Today, we focus on two popular but controversial books—Dr. Steven Gundry's The Plant Paradox and Carnivore Code from Dr. Paul Saladino. This podcast was originally published on August 27 2022 In this podcast, Dr. Guyenet, Dr. Kratz, and I discuss: How difficult it is to parse out accurate versus inaccurate and biased information and the regulated and systematic role of Red Pen Reviews in clearing up the confusion The 3 focus areas Dr. Guyenet and Dr. Kratz use to score the books they review and the importance of each How the health claims made in Carnivore Code compare to research AND anecdotal reports of people eating the diet…and how the main claim that humans evolved to be carnivores compares to evolutionary evidence Possible downsides or even dangers of the carnivore diet and if these caveats are discussed in the book The full truth of the claim that elevated LDL is not a cardiovascular concern if a person has excellent metabolic health Does a nose-to-tail carnivore diet provide all the nutrients you need each day? The Plant Paradox's primary claim that certain plant lectins lead to approximately 50 diseases…plus, what a lectin actually is! What current research tells us about lectins triggering leaky gut, inflammation, and autoimmune disease  The health status of people who eat large amounts of lectin-rich legumes, tomatoes, and other nightshade vegetables Could lectins and other plant foods be stressful BUT ALSO beneficial at the same time? Practical ways to evaluate the nutrition information you take in every day so you can more easily consider what's accurate and what's likely not  

Why are obesity rates skyrocketing in the modern world? Do we simply lack willpower, or are deeper forces at play? In this episode, I sit down with Dr. Stephan Guyenet, a renowned obesity researcher, science communicator, and author of the book The Hungry Brain.  With his expertise in neuroscience and eating behavior, Dr. Guyenet sheds light on the complex mechanisms behind our body's drive to store fat and the challenges we face in our modern food environment. Luckily, it's not all doom and gloom. Stephan also shares evidence-based strategies to outsmart our hungry brains and maintain a healthy body composition for life. In this interview, you'll learn . . . The brain's central role in body fatness, the influence of genetics on obesity risk, and the mismatch between our evolutionary wiring and today's food landscape Why our body's weight-regulating countermeasures often fail to protect against gradual weight gain The impact of stress and emotional eating on weight management The "starvation response" that makes sustained fat loss so challenging and weight regain so common How to navigate “treat meals” without sabotaging progress Evidence-based tips for naturally maintaining a healthy body composition without relying on willpower alone And more . . . Whether you're looking to lose fat, maintain your weight loss, or simply better understand the science of obesity, this episode offers valuable insights and actionable strategies to help you outsmart your hungry brain and achieve lifelong leanness. --- Timestamps: (0:00) Please leave a review of the show wherever you listen to podcasts and make sure to subscribe! (2:46) Shop Legion Supplements Here: https://buylegion.com/ and use coupon code MUSCLE to save 20% or get double reward points! (6:09) How does the brain relate to obesity and weight regulation? (8:59) What role do genetics play in individual differences in obesity risk and leanness? (19:35) How has the modern food environment contributed to the obesity epidemic? (24:31) Why do the body's weight-regulating countermeasures often fail to prevent excessive fat gain? (32:57) A practical tip for enjoying treat meals without keeping tempting foods stocked at home (36:26) My free quiz to answer all your diet questions: www.muscleforlife.show/dietquiz (37:15) The impact of stress and emotional eating on weight management (41:27) The neuroscience behind why so many people struggle with weight regain after dieting (46:49) Can the body's set point be lowered to maintain leanness, and how long might that take? (50:53) Evidence-based strategies for naturally maintaining a healthy weight without constant willpower (57:59) Where to find more of Dr. Stephan Guyenet's work and resources (58:28) Want 125 quick, easy, and delicious “fitness friendly” recipes? Get The Shredded Chef: https://legionathletics.com/products/books/the-shredded-chef/ (1:01:40) Subscribe and please share the podcast with a friend! www.muscleforlife.show --- Mentioned on the Show: Shop Legion Supplements Here: https://buylegion.com/ and use coupon code MUSCLE to save 20% or get double reward points! Take this free quiz to get science-based answers to all of your diet questions: www.muscleforlife.show/dietquiz Want 125 quick, easy, and delicious “fitness friendly” recipes? Get The Shredded Chef: https://legionathletics.com/products/books/the-shredded-chef/ Stephan's Twitter: https://twitter.com/sguyenet Stephan's Website: https://www.stephanguyenet.com/ The Hungry Brain Book: https://www.amazon.com/Hungry-Brain-Outsmarting-Instincts-Overeat/dp/1250081203/?tag=mflweb-20

The worldwide prevalence of obesity has nearly tripled in less than fifty years.    If we are more informed about potential health consequences than ever before, why are more and more adults choosing unhealthy eating habits that lead to weight gain, diabetes, and heart disease?    Dr. Stephan Guyenet, who has spent more than a decade studying the neuroscience of body fatness, argues that most of us aren't choosing our eating habits at all.   His book, The Hungry Brain, dives into the idea that eating behaviors aren't a result of weakness or poor willpower but of an evolutionary mismatch between our brain's ancient programming and our current environment.    Today, he sits down with Dotsie and Alexandra to explain how our brains are hardwired to seek the high-calorie, dopamine-releasing foods that our ancestors relied on and why that works against us in modern society.    You'll hear how your neurochemistry is influencing your eating habits, why you're suddenly hungry for dessert after being satiated by dinner, and what you can do to overcome some of these neurological triggers that make it difficult to change the way you eat.    If you've ever been frustrated by a craving or your habit of second helpings, don't miss this episode to hear why. If you want to change your stomach, you need to focus on your head.   “The greater variety of the types of foods that we have available to us, the more calories we will tend to eat at a meal, and we won't even necessarily feel any more full.” - Dr. Stephan Guyenet   What we discuss in this episode: - Dotsie's experience at the Plant-Based World Conference & Expo - How convenience, cost, and the palatable seduction of food have contributed to higher rates of obesity - Why do we have a greater eating drive than we did only a century ago? Dr. Stephan Guyenet explains how our ability to concentrate dopamine-releasing ingredients is qualitatively similar to the creation of crack cocaine  - The evolutionary mismatch: How our ancestors' drive to survive is working against us today - What do genetics have to do with our body composition and our penchant for overeating - Why you should focus on diet before exercise if you're hoping to lose weight - Understanding the two systems of our brain and why activities like exercise require overcoming the effort barrier of System 1 and thinking with System 2 - The fat regulatory system, the starvation response, and why “calories in, calories out” is not as simple as counting numbers on a nutrition label - The two things that slow your metabolic rate and what you can do about them - Simple things you can try to overcome your body's starvation response and limit your habit of overeating   Resources: - Website: StephanGuyenet.com   ★☆★ Click the link below to support the ADD SOY Act! https://switch4good.org/add-soy-act/ ★☆★ Share the website and get your resources here https://kidsandmilk.org/ ★☆★ Send us a voice message and ask a question. We want to hear from you! https://switch4good.org/podcast/ ★☆★ Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips https://switch4good.org/dairy-free-swaps-guide SUPPORT SWITCH4GOOD https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★  https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ FOLLOW US ON TWITTER ★☆★ https://mobile.twitter.com/Switch4GoodNFT ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good ★☆★ DOWNLOAD THE ABILLION APP ★☆★ https://app.abillion.com/users/switch4good

Episode #294. Hit the ground running in 2024 by pressing play on this must-listen episode. Hear the most valuable insights from 19 guests of The Proof, all packed into one episode that brings you the best of each one. 2023 was absolutely loaded with expert advice from some of the best researchers and practitioners in the world, and this episode combines many of them to bring you a powerful tool to have in your arsenal. This episode will take you on a curated journey through 2023's most important moments, including the must-knows about nutrition, fats, cardiovascular health, metabolic health, cancer and nutrition, and gut health. You'll hear from: Dr Alan Flanagan, Dr Ayesha Sherzai, Dr Christopher Gardner, Dr Dena Sherzai, Dr Gil Carvalho, Dr Inigo San Millan, Dr Joel Fuhrman, Dr Krystle Zuniga, Dr Matthew Nagra, Dr Mohammed Alo, Dr Neil Iyengar, Dr Philip Calder, Dr Roy Taylor, Dr Stephan Guyenet, Dr Suzanne Devkota, Dr Thomas Dayspring, Dr Urvi Shah, Dr Walter Willet, and Dr Will Bulsiewicz. We discuss: Intro (00:00) The dangers of misinformation (01:30) Which Foods Should You Eat to Stay Healthy? (05:17) Does the Quality of Foods Matter? (07:38) The Impact of the Average American Diet on Health (09:28) Do We Have Sufficient Evidence on How Nutrition Impacts Our Health? (12:04) How different diets measure up to health guidelines (15:11) Practical insights for doctors and patients (23:08) Saturated fat misunderstandings: Is saturated fat bad? (25:32) Understanding Essential Fats: Why are They Vital? (30:18) Low Conversion Rates: From ALA to EPA & DHA Explained (34:29) The Importance of Monitoring Omega 6 Intake (39:52) Keeping the brain healthy with omega 3 fatty acids (43:45) Biochemical Analysis in Three Cohort Observations of Walter Willet's Studies (56:54) Are Low-Fat Diets Good for Cardiovascular Health? (01:02:12) Polyunsaturated Fats and Cardiovascular Disease (01:04:14) Benefits of Switching from Saturated Fat to Unsaturated Fats (01:09:51) Which popular diets are truly heart-healthy? (01:10:23) Atherosclerosis and the role of lipids (01:18:22) The tests helpful in predicting cardiovascular disease risk (01:31:24) Cardiac Imaging: Understanding Imaging Tests (01:43:34) Can we take drugs that raise HDL to lower cardiovascular disease risk? (01:52:17) Metabolic Health, Mitochondria, and Nutrition (02:00:37) Twin cycle hypothesis (02:07:17) Linking Non-Alcoholic Fatty Liver Disease with Type 2 Diabetes (02:18:56) How Weight Reduction Can Be Revolutionary in Reversing Diabetes (02:31:36) Main drivers of type 2 diabetes (02:38:56) The role of nutrition in cancer treatment (02:45:56) Plant-based diet vs ketogenic diet (02:50:12) Can food act as medicine? (02:55:54) Nutrition priorities during cancer treatment (03:05:36) Dietary patterns and FODMAP intolerance (03:08:33) Effects of antibiotics to gut the microbiome (03:16:41) Analysing Kevin Hall's Research: Plant-Based Diet vs. Alternative Diets (03:23:37) Outro (03:33:38) To connect with this episode's featured guests, head to the full show notes. Make sure to keep an eye out for part two of this series. Sponsors: If you want to improve your health, you need to measure where you're currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon. Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.

Join us for a comprehensive conversation with Stephan Guyenet, a renowned neuroscientist and science writer, as we delve deep into the realms of obesity, nutrition, and the crucial role of the brain in food intake. In this episode, Stephan shares his extensive knowledge, debunking common myths and offering evidence-based insights on how to eat for health and fitness.

Stephan Guyenet on How the Brain Controls Eating and ObesityThis episode with Stephan Guyenet examines the brain processes that drive appetite and eating behavior. Stephan is a neuroscientist who has studied what drives many of us to overeat and become overweight, and why it is so hard to lose weight.  He did his Ph.D. in Neurobiology at the University of Washington, and wrote the popular heath blog, Whole Health Source. In 2017 he published a highly acclaimed book about this - The Hungry Brain.  It continues to garner praise and attention, and was featured last February on the New York Times' Ezra Klein podcast. Stephan has spoken at the Ancestral Health Symposium several times on topics relating to the metabolic and neurological processes that underlie eating behavior and obesity.Our conversation with Stephan touches on how evolution shaped our brain circuits to function in a way that is mismatched to the modern food environment.  Weight control is not a simple matter of willpower, but of better awareness to how our neurobiology and reward circuits respond to different foods.Here is a guide to topics discussed in this podcast episode:1:57       How Stephan got interested in the brain's role in obesity3:12       Obesity as a modern phenomenon and it's rarity in pre-industrial societies like the Hazda6:45       Theories on the cause of the obesity epidemic - macronutrients, processed foods, food abundance11:31     Why It's not just about carbohydrates or refined carbs14:10     And it's also not just about omega-6 seed oils17:10     Food cravings and calorie dense highly palatable food18:52     The evidence from rat studies24:29     Food combinations and dopamine release in the brain25:48     Sensory specific satiety28:03     Is palatability inherent in food, hardwired in the brain, or learned through conditioning?33:08     The mismatch between our brain reward circuits and modern processed foods36:09     What is dopamine and how does it work in the brain to induce cravings?45:07     How to extinguish food cravings by changing what we eat46:47     How low carb and low fat diets can both work48:11     The role of food flavor in appetite control49:52     Recruiting non-conscious brain circuits to support your weight loss goals50:33     Which diets Stephan thinks are best supported by the evidence56:17     Satiety and calorie density58:06     What Stefan is working on now Get full access to Ancestral Health Today Substack at ancestralhealth.substack.com/subscribe

What makes us overeat and why do we continue to do it when we know deep down, we really don't need or want to? Armed with a BS in Biochemistry and a PhD in Neuroscience Dr. Stephan Guyenet has thrown himself into research around the neuroscience of obesity for 12 years now and argues against problem being a lack of willpower or understanding of what to eat. Rather, that our appetites and food choices are led astray by ancient, instinctive brain circuits that play by the rules of a survival game that no longer exists. Circuits that sure don't give a toss how we look at the beach this summer! In this ep we talk about dopamine and pleasure foods, the blatant bullsh^t that manufacturers use in their marketing, how we are seduced by food and why do I go from not hungry to hungry after seeing that it's 'lunch time'.   SPONSORED BY TESTART FAMILY LAWYERS Website: testartfamilylawyers.com.au STEPHAN GUYENET Website: stephanguyenet.com TIFFANEE COOK Linktree:  linktr.ee/rollwiththepunches Website: rollwiththepunches.com.au LinkedIn:  linkedin.com/in/tiffaneecook/ Facebook:  facebook.com/rollwiththepunchespodcast/ Instagram:  instagram.com/rollwiththepunches_podcast/ Instagram: instagram.com/tiffaneeandcoSee omnystudio.com/listener for privacy information.

Stephan J. Guyenet, Ph.D. is an obesity researcher and health writer whose work ties together neuroscience, physiology, evolutionary biology, and nutrition to offer explanations and solutions for our global weight problem. He received a B.S. in biochemistry at the University of Virginia and a Ph.D. in neurobiology at the University of Washington. He is the author of the popular health website, Whole Health Source, and is a frequent speaker on topics of obesity, metabolism, and nutrition. https://www.stephanguyenet.com/about-stephan-guyenet/   BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post   SHOW NOTES: (11:16) Our brains determine our food intake and regulate our energy expenditure, in a way that works best in our ancestral environment, but not in our modern environment. (24:33) We consume calories for many reasons, hunger being just one of them. Likewise, satiety is just one of many reasons we stop eating. (34:40) As a rule of thumb, eat a diet of omnivorous whole foods that are lower in calorie density. (49:56) Fiber is not an essential nutrient. (58:35) Nutrient-to-energy is important to health, but once you have adequate intake, there's not much benefit in taking in more. (1:04:46) Most people in the US are more susceptible to obesity than others. Whether or not they actually become obese comes down to the environment they choose. (1:15:31) Blood pressure, on a genetic level, doesn't typically change as one gets older.   BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post   Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

You can find Stephen at:stephanguyenet.orgTwitter @sguyenetAre you curious about the intricate ties between obesity, our brains, and evolution? This episode promises to satiate that curiosity and deliver insights you can't afford to miss. Our guest, neuroscientist Stephan Guyenet, unravels the complexities of body fatness and its relationship with our brain. Fascinated by the dissonance between our evolved traits and our modern environment, Stefan takes us through a journey of how our ancestors interacted with food and exercise, compared to our current practices.We dissect the influence of diet and physical activity on body fatness, exploring the connections between calorie-dense, refined foods and increased body fatness. We also delve into how palatability and satiety play significant roles in weight regulation. Stephan enlightens us on the profound impact of our modern lifestyles on our circadian rhythms  and offers tips on how small changes can mitigate any adverse effects. He also shares valuable strategies on navigating food choices.We touch on the role of non-conscious brain systems in eating and how understanding these systems can help us better navigate our food choices and temptations. Stefan also explains  how different energy substrates impact our satiety levels.Perhaps our mst important topic, we agree to parter up for a new business venture, The Hadza Cafe! (Joking, maybe...)

We've apparently found the culprit for the obesity epidemic, and it's “ultra-processed foods”. They're the plastic-wrapped, industrially-produced foods with long lists of ingredients that apparently make up 60% of the average UK diet.In this episode of The Studies Show, Tom and Stuart tuck in to some “hyper-palatable” research on nutrition and health, discuss the main randomised trial in this area, and try (and immediately fail) to read out the whole definition of “ultra-processed foods” in one breath.The Studies Show is brought to you by the i, the UK's best daily newspaper. You can find the latest deals for subscriptions—including a 50% off deal for digital subscriptions—at this link. Thanks to the i for their support!If you're enjoying The Studies Show, then please consider becoming a subscriber. You can join as a free subscriber and get an email whenever we release an episode. If you join as a paid subscriber, you'll be able to access some features like ask-me-anything chats with Tom and Stuart, and (soon) paid-only episodes. Either way, you can subscribe by typing your email address below:Show Notes* Chris van Tulleken's Guardian article with a summary of the case against UPFs* The UN document giving all the details on the NOVA classification* Study rating people's agreement on which foods are in which NOVA category* Stuart's article on UPFs* Systematic review & meta-analysis on the UPF correlation with premature death* The NIH randomised controlled trial of UPFs versus unprocessed foods* Photos of the meals given in the experiment, from the study's Appendix* Interesting Twitter discussion with the RCT's lead author* Page with details on Stephan Guyenet's book, The Hungry BrainCreditsThe Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

In this episode of Veggie Doctor Radio, I interview the author of The Hungry Brain and former neuroscience and obesity researcher Dr. Stephan Guyenet on why humans overeat and what we can do about it. We also discuss his newest project and what he envisions for the future.       Trigger warning: This episode discusses weight loss and calorie intake concepts.       Ad-free episode: https://plantscription.substack.com/subscribe               Disclaimer: The information on this blog, website and podcast is for informational purposes only. It is not meant to replace careful evaluation and treatment. If you have concerns about your or your child's eating, nutrition or growth, consult a doctor.           DR. STEPHAN GUYENET https://stephanguyenet.com/ https://twitter.com/sguyenet        Mentions: Red Pen Reviews: https://redpenreviews.org/       Send me an email to yami@doctoryami.com with questions and topics       Sign up for my newsletter doctoryami.com/signup       MORE LISTENING OPTIONS Apple Podcasts: http://bit.ly/vdritunes Spotify: http://bit.ly/vdrspotify         NEWSLETTER SIGN UP https://doctoryami.com/signup           FIND ME AT Doctoryami.com Instagram.com/thedoctoryami Facebook.com/thedoctoryami Veggiefitkids.com       * * * *   MORE FROM ME   Read - http://veggiefitkids.com/blog Listen: http://bit.ly/vdrpodcast Watch - http://bit.ly/vfkvideos TEDx Talk - http://bit.ly/DOCTORYAMITEDX       * * * *       Questions? Email me: Yami@doctoryami.com

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Getting over my fear that going vegan would make me weak and unhealthy, published by Drew Housman on July 3, 2023 on The Effective Altruism Forum. I recently read a Richard Hanania article titled "Eating Animals and the Virtues of Honesty." It talks about the moral atrocity that is factory farming and how that relates to Hanania's personal dietary choices. I commend him for calling out how bad most animal agriculture is. Hanania understands that there is no excuse to torture so many sentient beings just because we like how they taste. He concedes it could very well be one of the worst crimes in human history. Given all that, he wishes he could be vegan. Unfortunately, he must continue to eat animals. If he stops, he will ruin his body composition: I just grant to the vegan that he has won the argument, and he is morally superior from a utilitarian perspective, but I want to be thin and have broad shoulders. His argument, as I understand it, boils down to the idea that he needs to eat animals in order be fit, strong, and healthy. His position made me think of these great tweets:I am tempted to poke fun at Hanania, but I used to have the exact same worry! So I am going to do the ethical thing and talk about my personal experience as a jacked vegan. I know it's easy to google “vegan weightlifter” or "vegan athlete" or visit r/veganfitness to find examples vegans with shoulders so broad they'd make Hanania weep. My goal with this post is to normalize the idea that even late 30's, tech working, regular guy vegans can be muscular and healthy. Sorry if this comes across as bragging, or if it's cringey. It just struck me while reading the Hanania piece that more people might go vegan if they felt they could do so without withering away. I want Hanania to know he can have his cake and eat it too! Were he to internalize that, how many people amongst his large audience could he influence to change their diets? How much suffering could he reduce? I don't think it would be easy, possible, or desirable for every vegan to have big muscles. Nor do I think that a fully vegan diet is the healthiest choice for everyone. All I'm saying is that if what's holding you back from going vegan is a deep rooted fear that doing so will cause you to have small shoulders, I think you should reconsider. Going vegan, maintaining my strengthWhen I first considered going vegan, I was also worried I'd become thin and weak. I'd read Stephan Guyenet's account of going vegan for 6 months. He struggled a lot, and it really gave me pause. Old friends who came to visit during that period did repeatedly ask me if I was sick, because of the amount of weight I had lost-- largely muscle. I had grown paler as well. Health and strength are priorities for me. I didn't want to become pale and frail. But after I got my first puppy I decided that I could no longer tolerate the idea of eating other sentient beings, so I stopped. I went vegetarian for a month, then vegan. I figured I could always start eating meat again if my body fell apart. The whole getting pale and weak thing just.didn't happen to me. At all. I kept expecting to lose weight, or at least lose muscle, but I never did. I have actually gained some muscle and weight over my 4 years as a vegan, while keeping to roughly the same workout routine. Maybe I'm just lucky. Or maybe the loudest voices online are the ones who either had a bad experience going vegan or are convinced they will if they try. Maybe it's not as hard as everyone makes it out to be. Here's me just before going vegan: And here I am after years of eating vegan: At 36, I can currently bench and squat more than when I was an avid meat eater in my early twenties. But am I destroying my health? To dispel the notion that I am only superficially healthy, I'll share some bloodwork. This section ca...

In this episode of Collective Insights we're joined by Dr. Stephen Guyenet, author of the acclaimed book, "The Hungry Brain". The topic? How the human brain affects our food choices. Dr. Guyenet lays the case that our ancient, instinctive brain circuits (hello, dopamine!) lead us astray in our food choices, and these circuits don't care about our long-term health goals. Rather than blaming individuals for their lack of willpower, he suggests that our appetites and food choices are driven by a survival game that no longer exists. Listen in as we take an eye-opening journey through cutting-edge neuroscience, gaining profound insights into why our brain undermines our weight goals and offers practical guidelines for eating intentionally. Sponsored by Qualia Mind: neurohacker.com/podcastoffer. Use code podcast when you shop Qualia Mind for 15% off your order. Get in touch. Instagram: https://www.instagram.com/neurohacker/. Facebook: https://www.facebook.com/neurohackercollective. Email: support@neurohacker.com.

Episode #260. Are you struggling to maintain a healthy weight and navigate the confusing world of diets and weight loss solutions? In this episode, join me as I dive into the science behind eating behaviours, obesity, and the challenges of losing weight with renowned researcher Dr Stephan Guyenet. Discover the different types of eating, the importance of controlling our food environment, and various evidence-based strategies for weight loss. With practical advice and insights from Dr Guyenet, you'll gain a better understanding of the complexities of weight management and how to make informed choices for your health. Don't miss this eye-opening conversation about the widespread issue of obesity and our brain's role in eating behaviours. Specifically, we discuss: Intro (00:00) From neurodegenerative disease to obesity neuroscience (01:36) The holiday weight gain (10:38) The problem with excess fat (14:37) 'Personal fat threshold' and diabetes (26:06) Main drivers of type 2 diabetes (31:26) The role of the hypothalamus in weight gain (38:55) Homeostatic vs. non-homeostatic eating (47:29) Genetics and the obesity epidemic (56:50) Models of obesity: carbohydrate -insulin vs. energy balance (1:00:21) The brain and obesity (1:10:34) The protein-leverage hypothesis (1:19:39) Carbohydrates, fat, and the Mediterranean diet (1:24:08) The weight loss puzzle: low carb vs. low fat diet (1:30:10) Foods that promote satiety on fewer calories (1:38:25) GLP-1 agonists (1:43:08) Is weight loss largely dependent on exercise? (1:55:06) Physical activity vs sedentary lifestyle (1:58:40) Mental health and sleep (2:00:28) Expert advice on how to stop overeating (2:05:11) Outro (2:05:59) To connect with Dr Stephan Guyenet, you can find him on Twitter or visit his website, https://www.stephanguyenet.com/. You can also purchase Dr Guyenet's widely acclaimed book, The Hungry Brain, to learn more about why we overeat and how to overcome this issue. Make sure to also check out Red Pen Reviews, where you can access free expert reviews on nutrition books. Discover more insights and supporting resources in the full show notes. Enjoy, friends. Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary two-week meal plan and high protein Plant Performance recipe book

[Content note: food, dieting, obesity] I. The Hungry Brain gives off a bit of a Malcolm Gladwell vibe, with its cutesy name and pop-neuroscience style. But don't be fooled. Stephan Guyenet is no Gladwell-style dilettante. He's a neuroscientist studying nutrition, with a side job as a nutrition consultant, who spends his spare time blogging about nutrition, tweeting about nutrition, and speaking at nutrition-related conferences. He is very serious about what he does and his book is exactly as good as I would have hoped. Not only does it provide the best introduction to nutrition I've ever seen, but it incidentally explains other neuroscience topics better than the books directly about them do. https://slatestarcodex.com/2017/04/25/book-review-the-hungry-brain/  

A new class of drugs for weight loss have become available and are showing promising results. That's welcome news, as a recent report estimates that half of the world's population is expected to be overweight or obese by 2035. Obesity is a disease which can lead to serious health complications–and most previous attempts at treating it have proven futile. Can the new weight-loss drugs turn the tide against this global threat?Louise Baur, president of the World Obesity Federation crunches the numbers on the global impact of overweight and obesity. Stephan Guyenet, a neurobiologist and author of “The Hungry Brain”, explains the neurological and genetic factors that influence weight gain. Chris van Tulleken, an infectious diseases doctor at University College London and author of the upcoming book “Ultra-Processed People”, explores how the modern diet is contributing to the obesity epidemic–and other health problems. Plus, host Alok Jha asks Natasha Loder, The Economist's health editor, how important the new skinny jabs are in the fight against obesity.For full access to The Economist's print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience. Hosted on Acast. See acast.com/privacy for more information.

A new class of drugs for weight loss have become available and are showing promising results. That's welcome news, as a recent report estimates that half of the world's population is expected to be overweight or obese by 2035. Obesity is a disease which can lead to serious health complications–and most previous attempts at treating it have proven futile. Can the new weight-loss drugs turn the tide against this global threat?Louise Baur, president of the World Obesity Federation crunches the numbers on the global impact of overweight and obesity. Stephan Guyenet, a neurobiologist and author of “The Hungry Brain”, explains the neurological and genetic factors that influence weight gain. Chris van Tulleken, an infectious diseases doctor at University College London and author of the upcoming book “Ultra-Processed People”, explores how the modern diet is contributing to the obesity epidemic–and other health problems. Plus, host Alok Jha asks Natasha Loder, The Economist's health editor, how important the new skinny jabs are in the fight against obesity.For full access to The Economist's print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience. Hosted on Acast. See acast.com/privacy for more information.

https://astralcodexten.substack.com/p/issue-two-of-asterisk …the new-ish rationalist / effective altruist magazine, is up here. It's the food issue. I'm not in this one - my unsuitability to have food-related opinions is second only to @eigenrobot's - but some of my friends are. Articles include: The Virtue Of Wonder: Ozy (my ex, blogs at Thing of Things) reviews Martha Nussbaum's Justice For Animals. Beyond Staple Grains: In the ultimate “what if good things are bad?” article, economist Prabhu Pingali explains the downsides of the Green Revolution and how scientists and policymakers are trying to mitigate them. What I Won't Eat, by my good friend Georgia Ray (of Eukaryote Writes). I have dinner with Georgia whenever I'm in DC; it's a less painful experience than this article probably suggests. The Health Debates Over Plant-Based Meat, by Jake Eaton (is this nominative determinism?) There's no ironclad evidence yet that plant-based meat is any better or worse for you than animals, although I take the pro-vegetarian evidence from the Adventist studies a little more seriously than Jake does (see also section 4 here). There's a prediction market about the question below the article, but it's not very well-traded yet. America Doesn't Know Tofu, by George Stiffman. This reads like an excerpt from a cultivation novel, except every instance of “martial arts” has been CTRL-F'd and replaced with “tofu”. Read This, Not That, by Stephan Guyenet. I'm a big fan of Stephan's scientific work (including his book The Hungry Brain), and although I'm allergic to anything framed as “fight misinformation”, I will grudgingly agree that perhaps we should not all eat poison and die. Is Cultivated Meat For Real?, by Robert Yaman. I'd heard claims that cultivated (eg vat-grown, animal-cruelty-free) meat will be in stores later this year, and also claims that it's economically impossible. Which are true? This article says that we're very far away from cultivated meat that can compete with normal meat on price. But probably you can mix a little cultivated meat with Impossible or Beyond Meat and get something less expensive than the former and tastier than the latter, and applications like these might be enough to support cultivated meat companies until they can solve their technical obstacles. Plus superforecaster Juan Cambeiro on predicting pandemics, Mike Hinge on feeding the world through nuclear/volcanic winter.

Our society's dominant narrative is that body size is a product of individual willpower. We are skinny or fat because of the choices we make: the kinds of food we buy, the amounts we eat, the exercise regimens we follow.Research has never been kind to this thesis. It's a folk narrative we use to punish people, not an empirical account of why residents of most rich countries are getting heavier over time. But, then, what account does fit the data?In his 2017 book, “The Hungry Brain,” Stephan Guyenet, a neurobiologist, argues that weight gain is less about willpower than it is the product of an evolutionary mismatch between our brains, our genetics and our environments. Now a new class of weight loss drugs is raising the possibility that we can change our brains to fit this new environment.Paired with diet and exercise, Ozempic and Wegovy caused anywhere from about a 15 percent to 18 percent loss of body weight over the course of just over a year in people classified as obese or overweight. And they do this in a way that aligns exactly with Guyenet's research: They don't make our bodies burn more calories, they make our brains crave less food.So I asked Guyenet on the show to talk me through his model of weight gain, the research on these new drugs and the strange implications of living with old brains in a new world.Mentioned:“Relationship between food habituation and reinforcing efficacy of food” by Katelyn A. Carr and Leonard H. Epstein“Dietary obesity in adult rats: Similarities to hypothalamic and human obesity syndromes” by Anthony Sclafani and Deleri Springer“Why Have Americans Become More Obese?” by David M. Cutler, Edward L. Glaeser andJesse M. Shapiro“Persistent metabolic adaptation 6 years after “The Biggest Loser” competition” by Erin Fothergill, Juen Guo, Lilian Howard et al.“The future of weight loss” by Stephan GuyenetUnder a White Sky by Elizabeth KolbertBook recommendations:Burn by Herman PontzerSalt Sugar Fat by Michael MossThe Secret of Our Success by Joseph HenrichThoughts? Guest suggestions? Email us at ezrakleinshow@nytimes.com.You can find transcripts (posted midday) and more episodes of “The Ezra Klein Show” at nytimes.com/ezra-klein-podcast, and you can find Ezra on Twitter @ezraklein. Book recommendations from all our guests are listed at https://www.nytimes.com/article/ezra-klein-show-book-recs.“The Ezra Klein Show” is produced by Emefa Agawu, Annie Galvin, Jeff Geld, Rogé Karma and Kristin Lin. Fact-checking by Michelle Harris and Kate Sinclair. Mixing by Sonia Herrero. Original music by Isaac Jones. Audience strategy by Shannon Busta. The executive producer of New York Times Opinion Audio is Annie-Rose Strasser. Special thanks to Pat McCusker and Kristina Samulewski.

Stephan Guyenet is a former researcher in the fields of neuroscience and obesity. He is the author of The Hungry Brain, a general-audience book about the neuroscience of overeating and obesity that was called “essential” by the New York Times Book Review. He is the founder and director of https://www.redpenreviews.org/, which publishes the most informative, consistent, and unbiased reviews of popular nutrition books available.

In this episode we speak with Dr. Stephan Guyenet about the connection between the brain and obesity. Dr. Guyenet is a former researcher in the fields of neuroscience and obesity. He is the author of The Hungry Brain, a general-audience book about the neuroscience of overeating and obesity that was called “essential” by the New York Times Book Review. He is the founder and director of Red Pen Reviews, which publishes the most informative, consistent, and unbiased reviews of popular nutrition books available. Learning Points: 1. What is the connection between the brain and obesity? 2. Is there a pharmacological path to treating obesity? 3. How is the gut involved with obesity? Social Media: https://www.redpenreviews.org/ https://www.stephanguyenet.com/ https://twitter.com/sguyenet

No one wants to overeat. And certainly no one wants to overeat for years, become overweight, and end up with a high risk of diabetes or heart disease– yet two thirds of Americans do precisely that. Stephan is a neuroscientist who, in this episode, will go into the topic of obesity. Stephan provides insights into obesity that are not normally spoken about. He talks in depth about the role of genetics, the brain, and hormones such as leptin that play in the regulation of fat mass. He dives deep into the factors that affect body weight, controlling appetite and controlling food intake and provides takeaways for people wanting to take advantage of what we know about the brain's role in regulating our body weight.This episode is for anybody wanting to understand the neuroscience of obesity. Why obesity is prevelant in our society and what role the brain plays in obesity. What impacts cravings and appetiteWhat is fatHow obesity has changed over the last 50 years Public health and obesity The brain's role in obesity Obesity as a genetic disorder?  Sponsors:KETONE-IQ- 20% DISCOUNT - NEURO20https://hvmn.me/NeuroMOMENTOUS SUPPLEMENTS - 15% DISCOUNT - NEUROhttps://www.livemomentous.com/neuroFind Stephan here:www.stephanguyenet.com/twitter.com/sguyenetYou can follow me or contact me here ---Newsletter: https://bit.ly/3ewI5P0Instagram: louisanicola_Twitter : louisanicola_YouTube: Louisa NicolaThe information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Neuro Experience podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

This week, I sit down with Dr. Stephan J. Guyenet, a neuroscientist, thinker and educator.  After earning a BS in biochemistry at the University of Virginia, he completed a PhD in neuroscience at the University of Washington, then went on to study the neuroscience of obesity and eating behavior as a postdoctoral fellow.  He has over 12 years of history in the neuroscience research world studying neurodegenerative disease and the neuroscience of body fatness.  His mission is to advance science and public health as a researcher, science consultant, and science communicator.  Publishing a book, The Hungry Brain, in 2017, he laid out the framework for understanding how our brains work with food. It was named one of the best books of the year by Publishers Weekly and called “essential” by the New York Times Book Review. Finally, he is the founder and director of Red Pen Reviews, which publishes the most informative, consistent, and unbiased popular health and nutrition book reviews available. This hour long conversation is very stimulating as we dive headlong into the upstream targets of food choice and body outcome. Enjoy, Dr. M

Has his Ph.D. in neuroscience, spent over a decade studying neurodegenerative disease & the neuroscience of body fatness, wrote the book "The Hungry Brain" and is the founder of Red Pen Reviews which publishes the most informative, consistent, and unbiased popular health and nutrition book reviews available. Let me know what you think Text me 587-217-8500

"I'd do anything to be healthy, except eat right and exercise." We laugh when the comedian shares this insight from the stage, but then cringe when we realize the truth of that in our own lives and the lives of those around us. What is going on? Intriguingly, our brains are finely tuned based on a world that for most – no longer exists. Extremely palatable foods combining sugar, salt, fat and the like didn't exist until recently in human history. As such, instincts designed to prevent starvation have carried us into a lifetime of obesity, diabetes and more. So what can we do?Welcome to the Health, Wellness & Performance Catalyst. Today's guest is neuroscientist and best-selling author of The Hungry Brain, Dr. Stephan Guyenet. He has a bachelors degree in biochemistry, a PhD in neuroscience and completed a post-doctoral fellowship on the neuroscience of obesity and eating behavior. His research publications in scientific journals have been cited more than 2,100 times. He doesn't simply identify the science behind why we do what we do. Instead, he provides key insights on how we – or our friends, coaching clients and others - can effectively change course and thus change our lives for the better. Looking for weekly tips, tricks and turbo boosts to enhance your life? Sign up for the CATALYST 5 here, a brief weekly bullet point list of 5 ideas, concepts or boosts Dr. Cooper has discovered to improve your personal and professional life!For more information about the Catalyst Community, earning your NBHWC-approved health & wellness coach certification, the annual Rocky Mountain Coaching Retreat & Symposium and much more, please see https://www.catalystcoachinginstitute.com/ or reach out to us Results@CatalystCoachingInstitute.com If you'd like to share the Be A Catalyst! message in your world with a cool hoodie, t-shirt, water bottle stickers and more (100% of ALL profits go to charity), please visit https://teespring.com/stores/be-a-catalyst If you are a current or future health & wellness coach, please check out our Health & Wellness Coaching Forum Group on Facebook: https://www.facebook.com/groups/278207545599218.  This is an awesome group if you are looking for encouragement, ideas, resources and more. Finally, if you enjoy the Catalyst Podcast, you might also enjoy the YouTube Coaching Channel, which provides a full library of freely available videos covering health, wellness & performance: https://www.youtube.com/c/CoachingChannelContact us: Results@CatalystCoachingInstitute.comTwitter: @Catalyst2ThriveWebsite: CatalystCoachingInstitute.com

The Better Show brings Stephan Guyenet to the show this week to talk his new book The Hungry Brain. Stephan has a BS in Biochemistry and a PHD in Neuroscience, with over 12 years in the neuroscience research field. The founder of Red Pen Reviews, an unbiased, non-profit, evidence-based review company that scores popular health and nutrition books available for the public based on their sources. We begin chatting about the evolution of diets and the level of obesity in society, as well as the changes that have driven the BMI increase over the past century. We venture into the science side of the episode to talk about Lipostats, the Hypothalamus and the brain stem. We discuss the behavioural side of obesity, and the reward circuits related to highly palatable food and consumption. We explore the solutions available to lose weight, and what are the best options for differing levels of obesity. We finish off the episode by talking about debunking sources and misinformation around nutrition and health. Are you A Healthcare Practitioner? Join The Estima Certification Program HereJoin the Hello Betty AMA here: https://www.hellobetty.club/ama We'd like to thank our sponsors, The DNA  Company - $50 discount using code "DRSTEPHANIE" at checkout. https://www.thednacompany.com/drstephanieHVMN Ketones - get 10% off your order with Promo Code “STEPHANIE”  https://hvmn.me/STEPHANIEAthletic Greens - redeem an exclusive offer here: athleticgreens.com/stephanieLMNT Electrolytes - A FREE 7-flavor sample pack! - https://www.drinklmnt.com/DrEstimaOrion Red Light Therapy - Use the code STEPHANIE10 for 10% off + 40% off storewide until September 5th https://www.orionrlt.ca/?ref=StephanieLumen - get $25 off your order with Promo Code “DRSTEPHANIE25” https://www.lumen.me/?fid=1799Ancestral Supplements - Use Promo Code “ASA10” for 10% off any purchase https://shop.ancestralsupplements.com/discount/Tribe10?rfsn=5900205.652074&utm_source=refersion&utm_medium=affiliate&utm_campaign=5900205.652074PRIMEADINE - get 10% Off your Order with Promo Code “DRSTEPHANIE10” - https://oxfordhealthspan.com/products/best-spermidine-supplementBIOOPTIMIZERS - receive 10% off your order with Promo Code "ESTIMA" - www.biooptimizers.com/drstephanie Episode Overview: 0:00 Introduction2:00 Stephen's Discovery of Obesity Research 8:00 Brain's Impact on Hunger & Obesity 19:30 When Fatness is a Good thing23:30 Obesity from an Evolutionary Lens32:00 Historical Trend of Obesity56:00 Lipostat & Leptin  1:09:00 Brainstem's Satiety Role 1:33:30 Tools to Circumvent Weight Gain   1:48:30 Red Pen's Empirical Reviews2:12:00 Conclusion Follow Me On Instagram: https://www.instagram.com/dr.stephanie.estimaGet yourself a copy of my best-selling book, The Betty Body - https://bettybodybook.comJoin the Hello Betty Community here - https://hellobetty.club Stephan's Links:The Hungry Brain Book Linkhttps://www.redpenreviews.org/

Drs. Karl and Spencer sit down with neurobiologist and obesity researcher Dr. Stephan Guyenet to discuss how the brain is the main organ involved in obesity. Learn: How the brain regulates our body fatness The difference between hunger and cravings Why we eat How the new GLP-1 class of medicines help Visit his blog See if you qualify for the GLP-1 medicines

In this episode, I speak with two world-class nutrition experts Dr. Stephen Guyenet and Dr. Mario Kratz. Dr. Guyenet is a neurobiologist and obesity researcher. His scientific publications have been cited more than 4,000 times by his peers. His book, The Hungry Brain, was named one of the best books of the year by Publishers Weekly and called "essential" by The New York Times Book Review. Dr. Kratz has a master's of science in nutritional sciences and a Ph.D. in nutritional sciences from the University of Bonn in Germany. He has been involved in arteriosclerosis research at the University of Münster in Germany. Dr. Guyenet and Dr. Kratz work together at Red Pen Reviews - a nonprofit organization dedicated to publishing unbiased, scientifically accurate reviews for different nutrition diet books that are hitting the market. 

I interview Dr Stephan Guyenet, who is a researcher and science communicator in the field of neuroscience of obesity. He has written an excellent book on the same topic - The Hungry Brain. In his book, he explains how the brain is the central organ responsible for gaining weight and body fat. Stephan finished his PhD in neuroscience from the University of Washington, and then spent 12 years as a full time researcher exploring the science of obesity and its link to the brain. Stephan is also the founder and director of a non-profit called Red Pen Reviews, an online publication where he and his fellow researchers review popular nutrition books for scientific accuracy. Nutrition is an area where unfounded claims are often made, so I'm grateful for Stephan and the team for putting in effort to help sift scientifically grounded nutrition books from pseudoscience. In this podcast, I explore with Stephan the neuroscience of why we get fat, and what we can do to stay fit.== What we talk about == 00:00 - Introduction to the podcast 01:20 - What is obesity and why should anyone care about it? 05:12 - The Ideal Body Mass Index & the Relationship between BMI and Ethnicity 10:24 - What exactly fat does in our body which make us unhealthy? 16:48 - What actually causes insulin resistance? 23:14 - How do excess calories that we eat ultimately end up into the fat cells? 29:15 - Why is ketogenic diet so popular? How does it really work? 31:07 - Why do we over-eat even when we don't want to? 58:14 - Non-homeostatic systems that make us overeat 1:07:38 - Is food addiction real? 1:17:15 - What people can really do to not get fat? 1:20:52 - Concluding Thoughts

This is an “ask me anything” (AMA) episode, which means a world-class expert and past podcast guest comes on the podcast to answer questions submitted by you, our podcast listeners. Stephan Guyenet spent 12 years in academia studying neurodegenerative disease and obesity neuroscience. He was a postdoctoral fellow at the Univeristy of Washington, studying the neuroscience of obesity and eating behavior. Previous to that he completed a PhD in neuroscience. Stephan is the author of the popular and well-received book ‘The Hungry Brain‘, which lays out the science behind the brain's role in obesity. To subscribe to Premium (and get the full episode) go here. Questions Answered In Full Episode “When someone undergoes liposuction or other surgery that removes adipose tissue, is there a sudden reduction in leptin levels? While this may reduce leptin resistance, could the drop in leptin lead to increased hunger over time?” “What is the current research around how chronic energy restriction (or following crash diets) affects appetite hormones and/ or appetite regulation long term? Is there a physiological mechanism influencing overeating attributable to appetite dysregulation caused by chronic dieting? I ask as this is something I am often tackling in my nutrition consultancy but research in biochemical and physiological mechanisms seems lacking.” “Can you talk about the conditions of anorexia and morbid obesity and how they essentially defy the rules of metabolic compensation? In other words- I understand anorexia to be a mental health condition where the individual starves themselves with a purpose to control weight. And morbid obesity being excessive consumption despite over fatness, etc. If the body has these numerous mechanisms by which calorie restriction or calorie over- consumption results in these compensatory processes-driving us to eat more/less slow us down/speed us up, and many more; do these individuals not “hear” these signals or are they just adept at ignoring them or is it that their bodies have lost the ability to compensate for their under or over consumption? Additionally, can anyone become anorexic or morbidly obese? Or is it merely genetics?” “Why do some SDRIs (serotonin–dopamine reuptake inhibitors) and serotonin precursors reduce hunger/appetite? E.g. 5-HTP and Wellbutrin (Bupropion)” “Question about the ideal weight program: As an iOS developer, my instinct is to assume determinism and quantifiability of the entire universe. I believe this to be fundamentally true. But what is hypothetically possible differs from what we can realistically know. I worry that attempts like yours to quantify some seemingly qualitative measures are doomed. I have similar concerns about happiness research. How do you reassure yourself you can really construct an algorithm that deciphers the “ideal weight program” for any given user – do you rely on averages?” a. Quick explanation of the ideal weight program “In 2018 a poster was presented at the annual meeting of the Society for Neuroscience titled ‘The human brain microbiome; there are bacteria in our brains!' which showed bacteria apparently penetrating and inhabiting the cells of healthy human brains. While the work was preliminary, have you heard of any further work in this area? What is your opinion on the possibility that, if bacteria do inhabit the brain, they could play a part in appetite regulation and/or obesity similar to how the gut microbiome can affect our health?” “It seems like there are significant differences in policies put forth between researchers from biomedical backgrounds and ones from public health policy backgrounds. Dr [David] Allison touched on this during recent interviews, noting that there is very little evidence regarding the efficacy of upstream obesity prevention interventions, such community gardens, combatting food deserts, nutrition education, and cooking classes. On the other hand, governments are increasingly turning to such interventions, as well as policies such as front of pack labelling (Canada, 2022), nutrition facts tables, calorie labelling on menus, as well as the aforementioned ones. Given your research on determinants of health and obesity, what are some of the most promising interventions to prevent NCD morbidity, as well as stones unturned in public health policy? Would you agree with individuals such as Dr Allison that in our current environment, the only efficacious interventions are drugs and bariatric surgery?” Question based on your debate on JRE with Gary Taubes: “Would the insulinogenic effect of protein, specifically something like whey protein which causes an insulin response, be something that should automatically refute Taubes arguments about insulins inherent role in increasing adiposity? Second, would overeating on any macronutrient increase insulin simply because you are eating more food (i.e. hypercaloric)?” “Are there best practices for the maximum duration someone should spend in fat loss (or weight gain) phases? Or perhaps an optimal ratio of fat loss phase duration to “maintenance” phase duration? For example, should fat loss phases be for a maximum of 12 weeks followed by maintenance of at least equal duration before resuming a fat loss phase? “I'm a naturally skinny guy who helps other naturally skinny guys bulk up. I think it largely comes down to a blunted pleasure response to food, smaller stomachs, and/or higher NEAT. A lot of us seem to be taller and more thinly built, too. But why do you think things are things so different for us? Why is it so hard to gain weight? And what can we do about it?” To subscribe to Premium (and get the full episode) go here.

Drive with Dr. Peter Attia Podcast Notes Key Takeaways “More than half of U.S. adults will be classified as actually having obesity at some point in their life if the current context is maintained. You see the same thing with type 2 diabetes.” – Dr. Stephan GuyenetThere is no demographic in the U.S. adults where we have not gotten much fatter over the last few decades – regardless of income, education, or geography – we're getting fatter than we wereObesity is highly heritable (about 75%) and preservedDifferences in body fatness between individuals are primarily determined by differences in how the brain is constructed and operatesAny time you eat something sweet, that food substance causes neuropod cells in the gut to send parallel signals to the brain which activates dopamine and tells us to seek out and eat more sweet foodsDietary tribal ideology can hold you back from finding the right foods for your bodyThe distribution of fat in the body is more related to insulin signaling; the total amount of fat in the body is related to energy intakeThe types of foods most addictive are generally a mix of carbohydrates and fat in optimal concentration which triggers dopamine and activates seeking behaviorWhen it comes to nutrition, author credentials are not indicative of the quality of information and publishers do not fact-check – be diligent and unbiased in your review or check out Red Pen Reviews (free to public)Read the full notes @ podcastnotes.org View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Stephan Guyenet is a neuroscientist focused on the neuroscience of obesity and energy homeostasis.  He is the author of the book, The Hungry Brain and founder/director of Red Pen Reviews. In this episode, Stephan explains how obesity has changed phenotypically over the course of human history as well as what might explain the dramatic increase in prevalence of obesity in the last few decades. He talks in depth about the role of genetics, the brain, and hormones like leptin play in the regulation of fat mass. He dives deep into two common theories of obesity—the carbohydrate-insulin model and the energy balance model and provides his take on which theory has stronger evidence. Additionally, he provides insights on how we're hard-wired to think about food and the consequences of modern foods designed for maximal pleasure. Finally, he goes through the factors that affect body weight, set points, and provides takeaways for people wanting to take advantage of what we know about the brain's role in regulating our body weight. We discuss: Stephan's neuroscience background and his focus on the nuances of obesity [2:15]; How obesity has changed for humans throughout history [8:00]; The association between obesity and adverse health outcomes, the “obesity paradox,” and confounders when relating BMI to longevity [14:00]; The sharp increase in obesity across demographics [23:30]; The hypothalamus and its role in obesity [30:00];  The role of the hormone leptin in obesity [40:00]; The genetic component of obesity [46:30]; Understanding the tendency of humans to store fat through an evolutionary lens [57:00];   The hedonic aspect of food, and how the brain reacts to modern, highly-rewarding foods [1:03:30]; How we are hard-wired to think about food [1:14:30]; A review of the “Carnivore diet” [1:21:45]; The energy balance model, carbohydrate-insulin model, and unifying the theories around adiposity [1:34:15]; Body weight set points: a hypothetical comparison of two individuals [1:41:45]; Takeaways for people who want to lose weight and keep it off [1:48:30]; Evidence that favors the energy balance model of weight gain [1:56:00]; The synergistic effect of fat and carbohydrates and observations that a low-fat diet or a low-carb diet can cause weight loss [2:04:30]; Red Pen Reviews [2:11:00]; More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

After earning a BS in biochemistry at the University of Virginia, Dr. Guyenet completed a Ph.D. in neuroscience at the University of Washington, then went on to study the neuroscience of obesity and eating behavior as a postdoctoral fellow.  He has spent a total of 12 years in the neuroscience research world studying neurodegenerative disease and the neuroscience of body fatness.  His publications in scientific journals have been cited more than 3,600 times by my peers. Today, Dr. Guyenet continues his mission to advance science and public health as a researcher, science consultant, and science communicator.  His book, The Hungry Brain, was released in February of 2017 and was named one of the best books of the year by Publishers Weekly and called “essential” by the New York Times Book Review.  Dr. Guyenet is a Senior Researcher at GiveWell and a scientific reviewer for the Examine.com Research Digest.  Dr. Guyenet is the founder and director of Red Pen Reviews, which publishes the most informative, consistent, and unbiased popular health and nutrition book reviews available.  He is the primary designer of an innovative course-based body weight management program called the Ideal Weight Program, which is part of the HumanOS platform.  Dr. Guyenet periodically contributes to the scientific literature and is a review editor at Frontiers in Nutrition. Today Clarissa and I spoke with Dr. Guyenet about: Dr. Guyenet's thoughts on food addiction Food Selection Motivational States Craving as a whole and Craving specific foods Genetic role Medications Exercise Body "set point" And more! Find Dr. Guyenet: Website Book: The Hungry Brain  Twitter The content of our show is educational only. It does not supplement or supersede the professional relationship and direction of your healthcare provider. Always seek the advice of your physician or other qualified mental health providers with any questions you may have regarding a medical condition, substance use disorder, or mental health concern.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Stephan Guyenet is a neuroscientist focused on the neuroscience of obesity and energy homeostasis.  He is the author of the book, The Hungry Brain and founder/director of Red Pen Reviews. In this episode, Stephan explains how obesity has changed phenotypically over the course of human history as well as what might explain the dramatic increase in prevalence of obesity in the last few decades. He talks in depth about the role of genetics, the brain, and hormones like leptin play in the regulation of fat mass. He dives deep into two common theories of obesity—the carbohydrate-insulin model and the energy balance model and provides his take on which theory has stronger evidence. Additionally, he provides insights on how we're hard-wired to think about food and the consequences of modern foods designed for maximal pleasure. Finally, he goes through the factors that affect body weight, set points, and provides takeaways for people wanting to take advantage of what we know about the brain's role in regulating our body weight. We discuss: Stephan's neuroscience background and his focus on the nuances of obesity [2:15]; How obesity has changed for humans throughout history [8:00]; The association between obesity and adverse health outcomes, the “obesity paradox,” and confounders when relating BMI to longevity [14:00]; The sharp increase in obesity across demographics [23:30]; The hypothalamus and its role in obesity [30:00];  The role of the hormone leptin in obesity [40:00]; The genetic component of obesity [46:30]; Understanding the tendency of humans to store fat through an evolutionary lens [57:00];   The hedonic aspect of food, and how the brain reacts to modern, highly-rewarding foods [1:03:30]; How we are hard-wired to think about food [1:14:30]; A review of the “Carnivore diet” [1:21:45]; The energy balance model, carbohydrate-insulin model, and unifying the theories around adiposity [1:34:15]; Body weight set points: a hypothetical comparison of two individuals [1:41:45]; Takeaways for people who want to lose weight and keep it off [1:48:30]; Evidence that favors the energy balance model of weight gain [1:56:00]; The synergistic effect of fat and carbohydrates and observations that a low-fat diet or a low-carb diet can cause weight loss [2:04:30]; Red Pen Reviews [2:11:00]; More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Dr. Stephan Guyenet received his doctorate in neuroscience and has developed expertise in the study of obesity and eating behavior. He is the author of the 2017 best-selling book:  The Hungry Brain: Outsmarting the Instincts That make us Overeat. He has also designed a course-based body weight management program called the Ideal Weight Program.   One interesting aspect for us at Food Junkies is how Dr. Guyenet upholds the belief that it IS calories that matter the most when it comes to obesity (and NOT sugar specifically).  He does however add that it IS the addiction to trigger foods, such as sugar that leads to overeating the calories that then lead to obesity.   In this episode: Dr. Guyenet's personal and professional journey The Obesity Model Processed Foods and Hyper-Palatability Food/Sugar Addiction Volume eating Weight loss/diets Signature question   Find Dr. Guyenet: Website: https://www.stephanguyenet.com/ Book: The Hungry Brain Twitter The content of our show is educational only. It does not supplement or supersede the professional relationship and direction of your healthcare provider. Always seek the advice of your physician or other qualified mental health providers with any questions you may have regarding a medical condition, substance use disorder, or mental health concern.

This week on the podcast Mikki speaks to Dr Stephan Guyenet, obesity researcher and neuroscience expert about energy balance, weight maintenance and the brain. Mikki and Stephan discuss the role of hormones, the food environment and the brain and how to manage to maintain a healthy weight when these tend to conspire against us.Stephan Guyenet has BS in biochemistry and a PhD in neuroscience, then went on to study the neuroscience of obesity and eating behavior as a postdoctoral fellow.  He has spent 12 years in the neuroscience research world studying neurodegenerative disease and the neuroscience of body fatness.  His publications in scientific journals have been cited more than 3,600 times  and today, he continues his mission to advance science and public health as a researcher, science consultant, and science communicator.  His book, The Hungry Brain, was released in February of 2017 and was named one of the best books of the year by Publishers Weekly and called “essential” by the New York Times Book Review.  He is a Senior Researcher at GiveWell and scientific reviewer for the Examine.com Research Digest.  He is also the founder and director of Red Pen Reviews, which publishes the most informative, consistent, and unbiased popular health and nutrition book reviews available.  He also periodically contributes to the scientific literature and is a review editor at Frontiers in Nutrition.Stephan can be found at https://www.stephanguyenet.com/Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenSave 20% on all NuZest Products with the code MIKKI20 at www.nuzest.co.nzSave 30% on Hoka One One with the code TEAMMIKKI at www.Hoka.co.nz

In this episode, I have a candid conversation with my friend, business partner, and personal trainer Pam Sherman.  Our society and especially women put a lot of emphasis on weight, and it can seem like you have spent a lifetime trying to lose those extra pounds.  Pam and I dive into why focusing on weight alone isn't the best thing to do and why it is important to have non-scale victories and goals. We share our own non-scale victories that we have had from working with each other and some of our client's victories as well.  Plus we answer some of our member's questions and let you in on the details of our new program for women in peri and post-menopause!  Episode mentioned: The Science Behind How to Lose Weight with Stephan Guyenet. Join the OnTrack group today and get $40 off your monthly membership for the life of your membership. Get the details here and use coupon code 40OFF at checkout.  The OnTrack is a group coaching program to help you balance your hormones, lose weight and sail through peri and post-menopause at a fraction of what it costs to work with Pam and me privately.   Pam has been a coach for 24+ years, starting as a group exercise instructor and personal trainer.  After struggling with her own weight Pam started strength training in 2014 and has never looked back. Pam's social links https://www.theperfectbalance.guru/ Instagram YouTube Karen Martel, Certified Hormone Specialist & Transformational Nutrition Coach and weight loss expert.  Visit https://karenmartel.com/  Karen's Facebook Karen's Instagram  

Are we really in control of our diet? What influences what we either put or keep out of our mouths? Why is fast food so prevalent and why do we as humans gravitate towards it so much? There's so much more to nutrition than calories in vs. calories out as explained by Dr. Stephan Guyenet in this episode. Dr. Guyenet completed his PhD in neuroscience followed by a post doctoral fellowship in the neuroscience of obesity and eating. He is the founder of redpenreviews.org, an editor for Frontiers in Nutrition, and a scientific reviewer for examine.com among other endeavors. Dr. Guyenet is passionate not only about nutrition, but in what sets the background for our diets and how they have evolved over time. In this episode we talk about the concept of an "ideal body weight," the drivers behind our urge to eat, our culture around food, and the obesity epidemic.  Dr. Guyenet's Links: Twitter Link Linkedin Show Outline How did you fall into the world of nutrition science and what gets you up every morning? What does preventive medicine mean to you? Is there an ideal weight? What can the average person do to get past their ‘setpoint” to an “ideal weight?” How should one construct their diet in accordance with impulses/preferences/nutrition? What are the factors that influence our weight the most? Is it all “will-power” as many claim it to be? Why is it so hard to understand that it's more than just will power? What drives our desire to eat? Can you talk about the neuroscience behind hunger? Why do we like ultra-processed foods so much? People tend to blame various specific nutrients such as sugar, fat, processed foods, etc. for the obesity epidemic. What do you think is there to blame for the obesity epidemic? How did the food environment come to be the way it is? How can we design a better food environment for ourselves? What can we do on a systems and community level? How do physicians and healthcare providers fit into helping patients/clients create a better food environment? If someone asks you, “How do I get healthy” while you're waiting for your coffee at Starbucks, what do you tell them in 2 minutes? Join our Mailing List HERE: Mailchimp

Apply for 1 on 1 online coaching HERETo get more details click HEREIn this episode, I am joined by Dr. Stephan Guyenet. Stephan is the author of the book "The Hungry Brain." He has his BS in biochemistry at the University of Virginia, and completed a PhD in neuroscience at the University of Washington, then went on to study the neuroscience of obesity and eating behavior as a postdoctoral fellow. In this episode we discuss:-(0:00): His background. -(5:50): Overview of how energetically costly the brain is. -(7:15): His thoughts as to why obesity is a current problem.  -(19:31): What are calorie-dense foods?-(32:00) What is food reward?-(33:25) Optimal foraging theory. -(38:45) The fat thermostat. -(48:40) His thoughts on leptin resistance. -(52:50) How sleep and stress play a role in what we eat. -(1:03:11) Practical applications for managing the hungry brain. Where to find Stephan:Twitter: @sguyenetWebsite:https://www.stephanguyenet.com/

EPISODE 127 - Stephan Guyenet specializes in the neuroscience of obesity and is an advocate for information accuracy in health communication. He received a BS in biochemistry from the University of Virginia and a PhD in neuroscience from the University of Washington, where he remained as a postdoctoral fellow studying the neuroscience of obesity. His scientific publications have been cited more than 4,000 times by his peers. His book, The Hungry Brain, was named one of the best books of the year by Publishers Weekly and called “essential” by The New York Times Book Review. Stephan is the founder and director of Red Pen Reviews, which publishes the most informative, consistent, and unbiased health and nutrition book reviews available. In the episode, he shares why he's changed his mind about saturated fat intake, how a diet higher in fiber can help with weight loss, weight loss/maintenance myths he'd love to get busted once and for all...and more! EPISODE WEBPAGE: thehealthinvestment.com/127 P.S. – If you're liking The Health Investment Podcast, be sure to hit “subscribe/follow” so that you never miss an episode

Click here to subscribe to Premium The pathogenesis of obesity is clearly complex. And the need to have a comprehensive model to explain this pathogenesis is important. One such model, termed the Energy Balance Model, has largely been the consensus paradigm of obesity scientists to this point. Specifically, a recently published paper in the American Journal of Clinical Nutrition by Dr. Kevin Hall and his colleagues outlined the various nuances of the model, as well as common misconceptions about the model. However, there are others who propose that this is not the correct model of obesity, but rather that obesity pathogenesis can be better explained by a model called the Carbohydrate-Insulin Model (CIM) of obesity. While this model has been proposed in various forms over the past couple of decades, the most recently published revision/update of this model was that put forward by Dr. David Ludwig and colleagues, in a Perspective published also in the AJCN, in December of 2021. In this episode, Dr. Kevin Hall (lead author of the paper mentioned above) and Dr. Stephan Guyenet are on the podcast to discuss the debate surrounding these two models. Specifically, the discussion will focus in on the Hall et al. (2022) and Ludwig et al. (2021) papers, as well as previous work leading up to both. Click here to access show notes for this episode Click here to subscribe to Premium  

Gary Taubes is a journalist, writer and low-carbohydrate diet advocate. Stephan Guyenet, PhD, is a neuroscientist and is also the founder and director of Red Pen Reviews.