Podcasts about opioids

Send us a textPharmacology & neurobiology of psychedelics & MDMA, focusing on isomers, sex-specific effects, and mechanisms in animal models. Not medical advice.TOPICS DISCUSSED:Biased agonism: Different drugs activate the same receptor (e.g., 5-HT2A) but trigger varied intracellular pathways, explaining why LSD is psychedelic while similar lisuride is not.Enantiomers & isomers: Mirror-image versions of drugs like MDMA (S and R forms) and LSD (four isomers) often produce distinct effects; only one LSD isomer is psychedelic, for example.MDMA isomer effects: S-MDMA induces stronger head twitches (psychedelic proxy) via serotonin release, and increases dendritic spines in male mice but not females; R-MDMA has somewhat different effects.Sex-specific drug responses: In mice, females show stronger psychedelic effects (head twitches) from psilocybin and DOI at the same dose, but males exhibit greater post-acute benefits like reduced opioid withdrawal.Psilocybin in opioid addiction models: A single dose reduces place preference for oxycodone and withdrawal symptoms in male mice more than females, with opposite spine density effects in reward-related brain areas.Mechanisms beyond 5-HT2A: Psychedelics involve other receptors like metabotropic glutamate receptors, forming dimers with 5-HT2A to enable dual signaling pathways; effects in subcortical regions like nucleus accumbens are 5-HT2A-independent.Clinical implications: Street MDMA may vary in S/R ratios, affecting experiences; clinical trials often use racemic mixtures without weight-adjusted dosing, potentially missing sex differences.ABOUT THE GUEST: Javier Gonzalez-Maeso, PhD is a professor of pharmacology and toxicology at Virginia Commonwealth University, with a PhD in medicine from Spain focused on G-protein coupled receptors and human brain studies in depression and addiction.RELATED EPISODE:M&M 230 | Psilocybin & MDMA: Inflammation, Stress & Brain-Body Communication | Michael WheelerSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Contributor: Alec Coston, MD Educational Pearls: BiPAP is often effective in severe asthma, but many patients struggle with mask tolerance due to intense air hunger–driven anxiety, often compounded by hypoxia. Benzodiazepines are commonly used for anxiety, but they can depress respiratory drive, making clinical improvement difficult to interpret (a lower RR may reflect sedation rather than true physiologic improvement). Low-dose fentanyl is a useful alternative when patients cannot tolerate BiPAP despite coaching. Opioids blunt the perception of dyspnea and are well established for treating air hunger. When carefully titrated, fentanyl provides anxiolysis without significant respiratory suppression. It is rapidly titratable (e.g., 25 mcg IV every 5 minutes). Evidence primarily comes from palliative and oncology literature, but growing clinical experience supports its use in severe asthma to improve BiPAP tolerance. Failure of fentanyl should prompt escalation to ketamine, often signaling impending need for intubation. References Pang GS, Qu LM, Tan YY, Yee AC. Intravenous Fentanyl for Dyspnea at the End of Life: Lessons for Future Research in Dyspnea. Am J Hosp Palliat Care. 2016 Apr;33(3):222-7. doi: 10.1177/1049909114559769. Epub 2014 Nov 25. PMID: 25425740. Summarized and edited by Meg Joyce, MS2 Donate: https://emergencymedicalminute.org/donate/ Join our mailing list: http://eepurl.com/c9ouHf

Fatal overdoses are rising among adults 45 and older and stigma often keeps this age group out of the conversation. In this episode, Dr. Philip Chan, Consultant Medical Director at the Rhode Island Department of Health and a practicing primary care physician, discusses Rhode Island's No Matter Why You Use campaign. Dr. Chan explains why middle-aged and older adults face elevated overdose risk, how isolation, medical prescribing, and a contaminated drug supply intersect, and why personal storytelling is key to reducing stigma about accessing care. The conversation also highlights Rhode Island's overdose prevention strategies—from widespread naloxone access to community partnerships—and shares lessons other states can apply to save lives and start conversations sooner.Webinar Registration - ZoomOverdose Prevention | ASTHO

In 2025, Cook County saw the fewest opioid overdose deaths in a decade. The West Side Heroin/Opioid Task Force has been at the forefront of that work. Host Jacoby Cochran and executive producer Simone Alicea visit the task force's new office near the Pulaski Green Line stop to learn more about their work, what's driving these trends, and how to use an opioid reversal drug. Want some more City Cast Chicago news? Then make sure to sign up for our Hey Chicago newsletter.  Follow us @citycastchicago You can also text us or leave a voicemail at: 773 780-0246 Learn more about the sponsors of this Jan. 29 episode:  Chicago Theater Week Steppenwolf Paramount Theatre Window Nation Access Contemporary Music – use promo code PIANO for 20% off Become a member of City Cast Chicago. Interested in advertising with City Cast? Find more info HERE

The governor expresses disdain with President Donald Trump's immigration crackdown in Minnesota, and a team of Vermont midwives is inviting you to learn more about efforts to open the first freestanding birth center in the state.

Dr. Beth Weise is the Research and Overdose Prevention Coordinator for The Sidewalk Project, a non-profit organization that aids unhoused, drug-using, survivor & sex worker populations by providing direct services including crisis response, system advocacy, wound care, job placement, medication-assisted treatment (MAT), and creative community resources for mental health. Her work aims to influence future drug policy with novel evidence-based research that also advocates and empowers people who use drugs to feel safe and prevent fatal overdose. At CannMed 26, Beth will present “Cannabidiol to Mitigate Opioid Induced Respiratory Depression“. During our conversation, we discuss: What causes Opioid Induced Respiratory Depression and how cannabinoids play a role How CBD can be used in combination with Naloxone to reduce withdrawal-related side effects How Beth's research can be applied in real-world scenarios Thanks to This Episode's Sponsor: Humanity Heroes Humanity Heroes provides compassionate support to the unhoused community by delivering essential supplies and resources directly to those in need. Humanity Heroes partners with other nonprofits by empowering them to extend their reach and impact within their own communities. Together, they strive to create a world where every person has access to the resources and support they need to thrive. Learn more at JoinHumanityHeroes.org Additional Resources: THRRIV.org [Webinar] Bridging the Gap: Tech-Supported Peer Connections to Reduce – Overdose Fatalities – Register for CannMed 26

Public Views About Opioid Overdose and People With Opioid Use Disorder JAMA Network Open This study completed a national web-based survey of 1552 adults in the United States in April 2025 to assess perceptions of opioid overdose deaths and opinions of people who use opioids. Those who responded to the survey primarily identified as female (60.5%) and aged 30-44 (33.7%). Political views varied, with 28.9% conservatives, 39.6% moderates, and 31.5% liberals. Most respondents viewed opioid overdose deaths as serious (88.2%). Respondents felt that people who use opioids (81%) and pharmaceutical companies (72.7%) were most responsible for reducing overdose deaths, with more liberals identifying pharmaceutical companies as responsible while moderates and conservatives more often identified individuals as responsible. 38.3% of respondents reported they were unwilling to have a person with OUD as a neighbor and 58.4% were unwilling to have a person with OUD marry into their family, with higher percentages of conservatives than liberals endorsing these beliefs.   Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM

The Counter Momentum of Spin, with Dr. Franco Musio – The Maduro regime was indicted by the US Department of Justice in 2020 (and again recently) as a significant hub of illegal drug transit and a state sponsor of narcoterrorism (to include abetting many drug cartels with their support of violence, human smuggling, and significant profits from the illicit production and selling of narcotics)...

This first Addy Hour episode of 2026 is a must-watch/must-listen. We delve into the truths about cannabis and opioid use in teens and adults, and we honestly consider the many reasons people use. We address stigma head-on and the ways it shows up for those navigating substance misuse, other mental health challenges, chronic illness or other health concerns. Our guests also highlight the necessity of meeting people where they are. We talk about the importance of embracing and welcoming folks back into the community, especially after times of treatment or rehab. We also push the boundaries to highlight the essential ways institutions and universities can learn from our communities, for the good of all. In this episode, you'll also hear powerful stories about our guests' journeys and their transformative work. You'll hear about programs providing addiction services within the church. And you'll hear about strategically establishing clinics in neutral zones between gang territories to facilitate accessibility across gang affiliations. This free-flowing and in-depth conversation will leave you inspired, encouraged, and empowered.

Mark Parrino has been involved with the delivery of health care and treatment for opioid use disorder (OUD) since 1974. As the president of the American Association for the Treatment of Opioid Dependence, Inc. (AATOD), he works with treatment providers across the country to develop and improve treatment protocols. In December 2022, AATOD worked with the National Association of State Alcohol and Drug Abuse Directors (NASADAD) to initiate a first-of-its-kind census of all patients currently receiving treatment from government-certified opioid treatment programs (OTPs). Their findings, based on responses from over 1,500 OTPs nationwide, show the breadth and distribution of addiction treatment in America, and are the product of almost fifty years of medication-assisted treatment (MAT) in the United States. I spoke with Mark about his census results, as well as the history of MAT, and specifically methadone, treatment in America. You can see the full report here. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, her second book, on the development of the opioid addiction medication industry, is under contract with the University of Chicago Press. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Mark Parrino has been involved with the delivery of health care and treatment for opioid use disorder (OUD) since 1974. As the president of the American Association for the Treatment of Opioid Dependence, Inc. (AATOD), he works with treatment providers across the country to develop and improve treatment protocols. In December 2022, AATOD worked with the National Association of State Alcohol and Drug Abuse Directors (NASADAD) to initiate a first-of-its-kind census of all patients currently receiving treatment from government-certified opioid treatment programs (OTPs). Their findings, based on responses from over 1,500 OTPs nationwide, show the breadth and distribution of addiction treatment in America, and are the product of almost fifty years of medication-assisted treatment (MAT) in the United States. I spoke with Mark about his census results, as well as the history of MAT, and specifically methadone, treatment in America. You can see the full report here. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, her second book, on the development of the opioid addiction medication industry, is under contract with the University of Chicago Press. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Male Loneliness Is Exploding...Tech, AI, and Society Are Making It Worse Scott Galloway — NYU Stern Professor of Marketing, serial entrepreneur, bestselling author of Notes on Being a Man, and one of the most influential voices on culture, masculinity, and economics — returns to Mayim Bialik's Breakdown for a brutally honest conversation about what's happening to young men today… and why it affects all of us. In this wide-ranging discussion, Galloway breaks down why young men are more lonely, economically insecure, and socially disconnected than any generation before them, and how technology, AI companionship, and synthetic relationships are hijacking young male brains at an unprecedented scale. We explore the growing maturity gap between men and women, why women are now surpassing men financially and educationally, and why young men are struggling so badly in the modern dating market. Scott also dives into the alarming rise of AI chatbots and synthetic relationships, especially among young people, and the hidden dangers no one is talking about. Scott also breaks down: - Why young men today are at a disadvantage compared to prior generations - How tech, AI, and economic insecurity are fueling male loneliness - Why women's success does NOT cause men to fail - Why young men are falling behind in education, income, and dating - Shocking prevalence of human–AI relationships and why they're dangerous - Why resilience is the most important trait for long-term success - Why older generations of men have a moral obligation to pay it forward - How single-parent households affect children, especially boys (The U.S. has the highest rate of single-parent homes in the world!) - Best ways to truly connect with your kids in a digital world - Why Scott identifies as a reluctant atheist and how belief, meaning, and purpose fit into modern life This is a conversation about masculinity, responsibility, technology, parenting, faith, and the future, and why fixing the crisis facing young men is one of the most important challenges of our time. Scott Galloway's latest book, Notes on Being a Man: ⁠https://a.co/d/0VNktwg⁠ Follow us on Substack for Exclusive Bonus Content: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bialikbreakdown.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BialikBreakdown.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube.com/mayimbialik⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

D.C. is set to receive more than 80 million dollars in opioid settlement money over the coming years. Survivors and their families say it's difficult to follow how it is actually spent.

In 2016, the Canadian federal government recognized the opioid crisis as a public health emergency, yet 10 years later, thousands of Canadians die from opioid toxicity every year.Health Canada committed $17 million to research projects and harm reduction initiatives aimed at substance use prevention in late 2025, but one problem that's hard to put a dollar figure on to fix is stigmatization and stereotypes surrounding safe consumption sites - which Ontario closed nine of last year.Host Maria Kestane speaks to Dimitra Panagiotoglou, the Canada Research Chair in the Economics of Harm Reduction and associate professor at McGill, to discuss her recent study on the relationship between crime associated with supervised consumption sites, and how Canadians can approach nuanced conversations surrounding substance use. We love feedback at The Big Story, as well as suggestions for future episodes. You can find us:Through email at hello@thebigstorypodcast.ca Or @thebigstoryfpn on Twitter

Some puppies are getting new homes after surviving an overdoes scare. AP correspondent Mike Hempen reports.

Male Loneliness Is Exploding...Tech, AI, and Society Are Making It Worse Scott Galloway — NYU Stern Professor of Marketing, serial entrepreneur, bestselling author of Notes on Being a Man, and one of the most influential voices on culture, masculinity, and economics — returns to Mayim Bialik's Breakdown for a brutally honest conversation about what's happening to young men today… and why it affects all of us. In this wide-ranging discussion, Galloway breaks down why young men are more lonely, economically insecure, and socially disconnected than any generation before them, and how technology, AI companionship, and synthetic relationships are hijacking young male brains at an unprecedented scale. We explore the growing maturity gap between men and women, why women are now surpassing men financially and educationally, and why young men are struggling so badly in the modern dating market. Scott also dives into the alarming rise of AI chatbots and synthetic relationships, especially among young people, and the hidden dangers no one is talking about. Scott also breaks down: - Why young men today are at a disadvantage compared to prior generations - How tech, AI, and economic insecurity are fueling male loneliness - Why women's success does NOT cause men to fail - Why young men are falling behind in education, income, and dating - Shocking prevalence of human–AI relationships and why they're dangerous - Why resilience is the most important trait for long-term success - Why older generations of men have a moral obligation to pay it forward - How single-parent households affect children, especially boys (The U.S. has the highest rate of single-parent homes in the world!) - Best ways to truly connect with your kids in a digital world - Why Scott identifies as a reluctant atheist and how belief, meaning, and purpose fit into modern life This is a conversation about masculinity, responsibility, technology, parenting, faith, and the future, and why fixing the crisis facing young men is one of the most important challenges of our time. Go to helixsleep.com/breakdown for a special partner offer including 27% off any purchase. If you're tired of being tired, this is your chance to finally get answers and get your energy back. Go to https://Superpower.com and use code BREAK for $20 off your membership this year. Scott Galloway's latest book, Notes on Being a Man: https://a.co/d/0VNktwg Follow us on Substack for Exclusive Bonus Content: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bialikbreakdown.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BialikBreakdown.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube.com/mayimbialik⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

A single syringe swap should never decide a patient's fate. We pull back the curtain on forty years of anesthesia medication safety to show what truly works—then tackle the hard part: getting proven safeguards into every OR, every time. From look-alike vial hazards to standardization that actually sticks, this conversation blends frontline realities with practical steps leaders can implement now.We dig into the high-stakes TXA wrong-drug, wrong-route crisis and explain why eliminating vials and moving to ready-to-administer IV bags is a must. Along the way, we unpack new FDA label warnings, the APSF–ISMP joint recommendations, and the forcing functions that prevent catastrophes, including NRFit for neuraxial routes and barcode verification at the point of care. We also surface quieter threats—vial coring, variable concentrations, and chaotic storages—and show how color-coded, readable labels and organized carts reduce cognitive load when seconds matter.Opioid safety gets equal focus. We connect preoperative risk assessment, multimodal analgesia, and smart postoperative monitoring to reduce opioid-related harm without compromising comfort. Technology has matured too: AI-driven clinical decision support can flag dosing and drug-choice risks in real time, but only if woven into workflows that clinicians trust. Throughout, we return to the implementation gap: success depends on leadership support, supply chain alignment, failure mode analysis, transparent reporting, and peer support that sustains a just culture.If you care about safer anesthesia—standardized labels and concentrations, prefilled syringes, organized storage, barcode checks, and a culture that learns—this is your playbook. Listen, share with your team, and help push your institution from knowing to doing. Subscribe, leave a review, and tell us which safeguard you'll champion next.For show notes & transcript, visit our episode page at apsf.org: https://www.apsf.org/podcast/289-forty-years-of-anesthesia-medication-safety-what-works-and-whats-next/© 2026, The Anesthesia Patient Safety Foundation

Opioidology Part 3: Opioid-Philia vs Opioid-Phobia The often-blurred lines of pain, addiction, and substance use need a deeper dive into the extremes of opioid-philia and opioid-phobia (building upon Opioidology Part 1: Our Opioid Story). Join Mark “Pain Guy” Garofoli and our two guests James Hackworth and Jim Potenziano to take that deeper dive based on their recent collaboration in the Frontiers in Pain Research article “The Burden of Acute Pain in the U.S. in the Wake of the Opioid Crisis”. • Frontiers in Pain Research Article: https://www.frontiersin.org/journals/pain-research/articles/10.3389/fpain.2025.1642035/full  • Article Key Takeaways • Rising Pain Prevalence • Balancing Act—Opioid Utilization vs. Undertreatment • Provider Reluctance to use opioids • Patient Reluctance • Massive Economic Impact • Call for Innovation & Policy Reform • Opioid Story charts: www.painguy.us

To justify bombing Venezuela and abducting President Nicolás Maduro, Donald Trump falsely accused him of leading the so-called "Cartel de los Soles". But the US Department of Justice was forced to admit that this "Suns Cartel" doesn't exist. The USA lied -- while the CIA actually has trafficked drugs in Latin America. Ben Norton reports. VIDEO: https://www.youtube.com/watch?v=44c0jf5ygyE Topics 0:00 US attacks Venezuela 0:21 (CLIP) Trump wants Venezuela's oil 1:12 Trump's colonial war on Venezuela 2:08 US DOJ admits it lied about Maduro 3:25 92-year-old judge oversees show trial 3:53 "Cartel de los Soles" doesn't exist 5:05 WMD lie 5:46 Venezuela does NOT produce fentanyl 6:28 Cocaine-producing countries 7:12 (CLIP) Biden official admits truth 8:21 CIA trafficked drugs in Venezuela 11:01 (CLIP) 60 Minutes on CIA drug trafficking 11:42 DEA agent accuses CIA of trafficking 12:58 CIA, cocaine, Nicaraguan Contras 14:47 Trump pardoned Hondura drug trafficker 16:13 (CLIP) Juan Orlando Hernández 16:39 Ecuador's drug-linked President Noboa 17:42 Colombia's drug lord Álvaro Uribe 18:50 USA armed Mexican cartels 19:34 US allies in Mexico are narcos 20:23 Drug links to Argentina's Javier Milei 20:43 Marco Rubio's links to cocaine trafficking 22:52 US Special Forces links to drugs 23:55 Trump attacks Colombia President Petro 24:37 Afghanistan opium production 25:59 Opioid epidemic in USA 26:34 Purdue Pharma and Sackler family 28:55 US imperialism based on lies 29:42 Outro

A highlight from exceptional sessions at the 2025 Midyear Clinical Meeting & Exhibition, this episode explores how pharmacists can bridge gaps in care for patients with opioid use disorder (OUD), highlighting strategies for prescribing and optimizing medications for OUD across primary, ambulatory, and acute care settings. We will discuss real-world examples, emerging practices like microdosing and direct-to-inject techniques, and ways pharmacists can make a tangible difference in improving patient outcomes. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.

In this episode, Dr. Blythe Bynum joins the show to discuss her new article titled Navigating Choices: Pregnancy Options Counseling Experiences in Individuals With Opioid Use Disorder, featured in the November/December issue of the Journal of Addiction Medicine. Dr. Blythe Bynum is an assistant professor in the Department of Obstetrics and Gynecology at Thomas Jefferson University in Philadelphia, Pennsylvania. She is a board certified OBGYN with fellowship training in Complex Family Planning.    Article Link: Navigating Choices: Pregnancy Options Counseling Experiences in Individuals With Opioid Use Disorder

Quality Improvement and Patient Safety In this episode, Dr. Kevin Koo joins Dr. Andrew Harris, Chair of AUA's Quality Improvement and Patient Safety (QIPS) Committee, for a conversation on opioid prescribing practices and patient-reported pain outcomes following percutaneous nephrolithotomy (PCNL). They discuss the development and implementation of a tailored opioid prescribing algorithm that reduced unnecessary prescriptions, ensured adequate pain management, and highlighted the importance of multimodal analgesia in postoperative care.

Moderator: James P. Rathmell, M.D. Participants: Mark Bicket, M.D., Ph.D. and Lynn Kohan, M.D. Articles Discussed: Trends in Use of Medications for Opioid Use Disorder among Commercially Insured U.S. Surgical Patients, 2016-2022 Rising Treatment for Substance Use Disorder Presents New Challenges for Anesthesiologists as Perioperative Medicine Specialists Transcript

"Suzetrigine as a Non-Opioid Analgesic: Balancing Promise with Prudence." From ASRA Pain Medicine News, November 2025. See the original article at www.asra.com/november25news for figures and references. This material is copyrighted. Support the show

It's been nearly three years since landmark settlements were reached between states and major opioid producers. Since then, roughly $100 million has been dispersed to combat addiction, but it's unclear how much of that money has been spent so far.   The Current's Alena Mashke joins us for more on the lack of spending transparency. From Star Wars to Jurassic Park, Hollywood movies and TV shows have long relied on special effects to bring supernatural stories to life. This process often involves sculpting, puppetry, animatronics and technology – and has many times involved Louisiana native and Emmy-award winning special effects artist, Lee Romaire.Romaire grew up in Morgan City, Louisiana, before attending LSU and later moving to Hollywood to pursue a career in the industry. He joins us now for more on his 25 years in special effects and how his background in taxidermy set the foundation for his career.Tomorrow night marks the beginning of the 2026 Mardi Gras season. And in New Orleans, the Krewe of Joan of Arc will take to the streets on Twelfth Night. Back in 2018, WWNO's Jessica Rosgaard spoke with the Krewe's founder, Amy Kirk Duvosin, about the parade's history.—Today's episode of Louisiana Considered was hosted by Karen Henderson. Our managing producer is Alana Schreiber. We receive production and technical support from Garrett Pittman, Adam Vos and our assistant producer, Aubry Procell. You can listen to Louisiana Considered Monday through Friday at noon and 7 p.m. It's available on Spotify, the NPR App and wherever you get your podcasts. Louisiana Considered wants to hear from you! Please fill out our pitch line to let us know what kinds of story ideas you have for our show. And while you're at it, fill out our listener survey! We want to keep bringing you the kinds of conversations you'd like to listen to.Louisiana Considered is made possible with support from our listeners. Thank you!

Buprenorphine is well-known for opioid use disorder—but what about for acute pain? Drs. Terry Ahern and Jon Lee join host Maiya Smith to discuss low-dose buprenorphine for pain management in the emergency room, covering pharmacology, dosing, patient selection, and why it may be a safer, underused analgesic.  

⏰ Time for a Checkup ⏰ Dr. Luke Enderiser from AltaPointe joined Sean Sullivan to talk about something our community truly needs: First Step, a new six-bed, medically managed withdrawal unit in Mobile. This is real help for people trying to step away from alcohol or opioids safely and with dignity. Here's the part that stops you mid-scroll:  Quitting alcohol “cold turkey” can actually be dangerous, even deadly, without medical support. Opioid withdrawal may not be life-threatening, but it can be so painful that it becomes the wall people can't climb alone. First Step exists to help people through that wall with medical care, proven medications, and compassionate support. And it doesn't end there. After withdrawal, AltaPointe connects patients with peer specialists, therapists, outpatient or inpatient programs, and medications that reduce cravings and help sustain recovery. This is not just about stopping. It's about starting over with support. If this hits close to home for you or someone you care about, help is just a phone call away:  

John Greenwood, Chief Strategy Officer & Co-founder of Goldfinch Health, joins guest host Thomas Beadle to discuss how they are trying to reduce the unnecessary use of opioids for surgery recovery.See omnystudio.com/listener for privacy information.

60 MinutesPG-13This is a re-release of an episode with Trey Garrison. He is an author and investigative reporter who came on the show to talk about a book he wrote with his partner Richard McClure, "Opioids for the Masses: Big Pharma's War on Middle America and the White Working Class"Opioids for the MassesPete and Thomas777 'At the Movies'Support Pete on His WebsitePete's PatreonPete's SubstackPete's SubscribestarPete's GUMROADPete's VenmoPete's Buy Me a CoffeePete on FacebookPete on TwitterBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-pete-quinones-show--6071361/support.

On the Tuesday, Dec. 23rd edition of Georgia Today: An update on the men who escaped the DeKalb County jail; Federal charges have been filed against an Atlanta Housing Authority executive; UGA researchers warn that opioid pain medications may increase infection risk

Mississippi Today health reporter Allen Siegler and health editor Laura Santhanam give an update on the state's plan to spend its initial pot of opioid lawsuit settlement money. Siegler's in-depth reporting has chronicled some issues and raised serious questions about how the state and local governments are spending the money, which is supposed to help address the scourge of opioid addiction, which has cost at least 10,000 lives in Mississippi since 2000.

A state-mandated task force led by Mayor Joe Hogsett has recommended a major shakeup for Indianapolis schools. Lauren Roberts is seeking damages from the City of Indianapolis after she was forcibly removed from a City-County Council meeting earlier this year. Indiana University is expanding its emergency opioid response. After Indiana cut preschool scholarships, communities are looking for ways to fill the gap. Parkview Health and the University of Notre Dame are partnering together, with help from a development fund, to create an AI-enabled solution to improve health care in rural communities. An Indianapolis tutoring program to address K through third-grade literacy gaps at public schools says it has improved reading for over 750 at-risk students. If you shop for holiday décor this year, experts say to expect higher prices and less inventory. Want to go deeper on the stories you hear on WFYI News Now? Visit wfyi.org/news and follow us on social media to get comprehensive analysis and local news daily. Subscribe to WFYI News Now wherever you get your podcasts. WFYI News Now is produced by Zach Bundy, with support from News Director Sarah Neal-Estes.

Take your veterinary dental expertise to the next level — save $100 on any online course with code START26! Access our full library of live and on-demand courses today: https://internationalveterinarydentistryinstitute.org/veterinary-dental-online-webinars-courses-discount/?utm_source=podcast&utm_medium=podcastlink&utm_campaign=start26  —------------------------------------------------------------------- Host: Dr. Brett Beckman, DVM, FAVD, DAVDC, DAAPM In this episode of The Vet Dental Show, Dr. Victoria Lukasik, DVM, DACVAA, discusses strategies for optimizing pre-anesthetic medication protocols. They discuss how drug choices, administration sites, and dosages impact sedation quality, patient experience, and potential side effects. Gain insights into selecting appropriate tranquilizers, analgesics, and anticholinergics to enhance patient comfort and safety during dental procedures. What You'll Learn:  ✅ Understand the impact of premedication administration sites on drug efficacy.  ✅ Discover the benefits of intranasal Dexmedetomidine for sedation.  ✅ Simplify the selection of appropriate tranquilizers and analgesics.  ✅ Apply strategies to minimize opioid-induced side effects in cats.  ✅ Master the use of anticholinergics and preventative eye care.  ✅ Recognize the importance of considering non-anesthetic drugs. Key Takeaways:  ✅ Intramuscular injections into the semimembranosus muscle provide higher quality sedation with more predictable onset times.  ✅ Intranasal Dexmedetomidine offers comparable sedation to IM administration with reduced cardiovascular effects.  ✅ Diphenhydramine (Benadryl) can lower blood pressure; monitor patients accordingly.  ✅ Tailor opioid selection based on patient-specific needs, considering chronic pain and potential psychological effects.  ✅ Cats with dilated pupils may be sensitive to bright light; minimize light exposure to reduce stress. Questions This Episode Answers:

We tell athletes to “shake it off,” “tough it out,” and “get back in the game.”But what happens when the injury is inside the brain, quiet, cumulative, and deadly?In this episode of Hope Illuminated, Dr. John Gaal shares the devastating story of losing his 24-year-old son to suicide and the painful discovery afterward that his son's brain showed hallmark signs of Chronic Traumatic Encephalopathy (CTE).That grief became a catalyst for John's work at the intersection of repetitive head trauma, depression, pain, opioids, identity loss, and suicide risk, especially among athletes.This conversation brings together heart and science to ask a question our culture often avoids:How many deaths are we calling “mental health problems” when they may also involve brain injuries we never diagnosed? For more information on this episode go to https://www.sallyspencerthomas.com/hope-illuminated-podcast/157

“Behind the Evidence” is the addiction medicine podcast of the Grayken Center for Addiction at Boston Medical Center, and a project of the Center's free bimonthly newsletter Alcohol, Other Drugs, and Health: Current Evidence (AODH). This episode was recorded 19 May 2025 and features an interview with J. Cedric Woods, PhD on his article, “Trends in Fatal Opioid-Related Overdose in American Indian and Alaska Native Communities, 1999-2021” published in The American Journal of Preventative Medicine. Click here to read AODH's summary of this article.Hosts: Honora L. Englander, MD and Marc R. Larochelle, MDProduction: Raquel Silveira, MBAEditing: Casy Calver, PhDMusic and cover art: Mary Tomanovich, MAMiriam Komaromy, MD is the Executive Director of the Grayken Center for Addiction, and co-Editor-in-Chief of AODH, together with David Fiellin, MDLearn more about AODH and subscribe for free at www.aodhealth.org“Behind the Evidence” is supported by the Grayken Center for Addiction at Boston Medical Center. It is intended for educational purposes only, and should not be considered medical advice. The views expressed here are our own, and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Tomi Lahren sits down with interventionist and recovered addict Darren Hobbs, known for his work helping families on A&E's Intervention, for a powerful and emotional conversation about addiction, the fentanyl crisis, and what it really takes to save lives in today's opioid epidemic.If you or someone you love is struggling with addiction, this candid discussion offers hope, guidance, and real-world insight from one of the leading interventionists in the country. This episode is sponsored by Incogni. Take your personal data back with Incogni! Use code TOMI at the link below and get 60% off an annual plan: https://incogni.com/tomi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Michael Smerconish dives into today's provocative poll question: Would legalizing heroin and cocaine actually reduce fentanyl deaths and improve global stability? Inspired by a listener's message and supported by Kofi Annan's striking 2016 essay, Michael examines the arguments for and against a radical shift in drug policy. He also updates listeners on the ongoing mystery around the unreleased video of the second Venezuela boat strike and how the administration's messaging continues to shift. Listen here, then vote! Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Welcome to the Legal Nurse Podcast, where complex medical topics meet the world of litigation. In this episode, host Pat Iyer sits down with Dr. Allison Muller, a seasoned toxicologist who brings her expertise to the forefront of the ongoing opioid crisis. Together, they delve into the multifaceted role opioids play in patient care, legal cases, and toxicology, offering invaluable insights for legal nurse consultants and medical professionals alike. Throughout their conversation, Pat Iyer and Allison Muller unpack the intricacies of opioid administration, the significance of accurate medical record documentation, and the challenges of interpreting toxicology reports, especially in postmortem cases. Dr. Muller sheds light on key concepts such as opioid tolerance versus naivety, risks of over-sedation, and the life-saving but often misunderstood role of naloxone in reversing opioid overdoses. Whether you're navigating your first toxicology-related case or looking to deepen your understanding of opioid implications in acute care settings, this episode offers practical guidance and real-world examples. From common pitfalls in toxicology interpretation to the criteria for bringing a toxicologist onto your legal team, Dr. Muller and Pat Iyer provide a roadmap for safer patient care and stronger case outcomes. What you'll learn in this episode on Navigating Opioid Cases: Insights from a Toxicologist on Medical Records and Overdose Risks Here are five intriguing questions that this podcast answers: How should medical records be reviewed to accurately track opioid administration in acute care settings, and what are the limitations of toxicology blood levels in this context? Why do toxicology reports from autopsies take so long to be completed, and what complexities are involved in determining the substances present in a decedent's system? What is the difference between opioid naive and opioid tolerant patients, and why is understanding these distinctions critical for safe opioid prescribing? What are the best practices for administering Naloxone (Narcan) in cases of opioid overdose, and why is timing so crucial for its effectiveness? When is it appropriate for a legal nurse consultant to recommend involving a toxicologist in a case, especially when interpreting complex toxicology results? Listen to our podcasts or watch them using our app, Expert.edu, available at legalnursebusiness.com/expertedu. Get the free transcripts and also learn about other ways to subscribe. Go to Legal Nurse Podcasts subscribe options by using this short link: http://LNC.tips/subscribepodcast. Grow Your LNC Business 13th LNC SUCCESS® ONLINE CONFERENCE April 23, 24, and 25, 2026 Skills, Strategy, Results Gain deposition mastery, marketing confidence, and clinical–legal insight from industry leaders you can apply to your next case and client call. Build a Practice Attorneys Remember Learn exactly how to showcase expertise, attract referrals, and turn complex medical records into clear, defensible stories that win trust. Learn From the Best—Then Ask Them Anything Get step-by-step training, live “hot seat” solutions, and exclusive VIP Q&A time with Pat Iyer to accelerate your LNC growth. Register now- Limited spots available Your Presenters for Navigating Opioid Cases: Insights from a Toxicologist on Medical Records and Overdose Risks Pat Iyer Pat Iyer is a seasoned legal nurse consultant and business coach renowned for her expertise in guiding new legal nurse consultants to successfully break into the field. As the host of the Legal Nurse Podcast, Pat addresses critical challenges that legal nurse consultants face, such as difficulty in landing clients and lack of response from attorneys. Through her insightful episodes, she emphasizes the importance of effectively communicating one's value to potential clients. With a wealth of experience, Pat has empowered countless consultants to overcome these hurdles and thrive in their careers. Connect with Pat Iyer by email at patiyer@legalnusebusiness.com Allison Muller Toxicologist with a passion for science, family, and the outdoors. Board-certified clinical toxicologist, fellow of the American Academy of Clinical Toxicology, affiliate fellow of the American College of Medical Toxicology, and faculty at the University of Pennsylvania School of Veterinary Medicine. Scientist with a flair for explaining the hard stuff to the triers of fact and anyone who wants to learn toxicology! When she isn't on this podcast, she's caring for an orange tabby cat and a dwarf bunny (luckily the tabby doesn't know his best friend is a bunny!) Connect with Allison Muller by email at Allison@AcriMullerConsulting.com

For families, the tragedy of opioids is beyond measure. The opioid epidemic has claimed tens of thousands of lives in Canada and has been recognized as a public health crisis, but it's also an economic one – and it disproportionately affects workers in key sectors like construction and the trades. As Ottawa ramps up its push to build major projects fast, could the ongoing toxic drug crisis slow it down?Today, Globe reporter Jason Kirby joins the show. As part of our Poisoned series, he spoke with workers, companies, unions and health researchers to understand the grip the crisis has on the construction industry and what's being done about it.Questions? Comments? Ideas? Email us at thedecibel@globeandmail.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

SPONSORS: 1) AMENTARA: Go to https://www.amentara.com/go/julian and use code JD22 for 22% off your first order! 2) MOOD: Discover your perfect mood and get 20% off your first order at http://mood.com and use code JULIAN at check out! 3) HOLLOW SOCKS: For a limited time Hollow Socks is having a Buy 2, Get 2 Free Sale. Head to http://Hollowsocks.com today to check it out. . #Hollow Sockspod PATREON: https://www.patreon.com/JulianDorey (***TIMESTAMPS in description below) ~ Tyler Oliveira is an American YouTuber. He made several challenge videos before transitioning to videos centered on man-on-the-street interviews and deep dive documentaries. TYLER's LINKS: YT: https://www.youtube.com/tyleroliveira X: https://x.com/tyleraloevera IG: https://www.instagram.com/tyleroliveiraofficial/# FOLLOW JULIAN DOREY INSTAGRAM (Podcast): https://www.instagram.com/juliandoreypodcast/ INSTAGRAM (Personal): https://www.instagram.com/julianddorey/ X: https://twitter.com/julianddorey JULIAN YT CHANNELS - SUBSCRIBE to Julian Dorey Clips YT: https://www.youtube.com/@juliandoreyclips - SUBSCRIBE to Julian Dorey Daily YT: https://www.youtube.com/@JulianDoreyDaily - SUBSCRIBE to Best of JDP: https://www.youtube.com/@bestofJDP ****TIMESTAMPS**** 00:00 – Intro 01:14 – Cow-Dung Festival, Shiva Origin, Lakshmi, Rituals, India Cow Laws, Cancer Claims 09:42 – Cow Dung Studies, Small Village Tradition, Caste System, Infant Mortality 24:24 – Gender Dynamics, Immigration Balance, Racism Labels, American Identity Unraveling 36:36 – Assimilation Debate, Economic Exploitation Claim, Identity Crisis, Hamtramck & Dearborn 50:51 – Importing Conflicts, Genocide Examples, Kensington Crisis, H1B Lottery 01:02:41 – Nepotism, Diploma Mills, Visa Farms, Scammer Systems at Scale 01:20:33 – Remittances, Japan Demographics, Immigration, Youth Opportunity Loss, AI Arms Race 01:30:58 – Risk/Reward of Immigration, Fourth Turning, Dangerous Male Energy 01:40:20 – Fixing America, Who Benefits?, Housing Crisis, Corporate Power, Crony Capitalism, AI God 01:53:07 – Unabomber, Pyramids, Scammers, Epstein Island 02:09:20 – Influencer Binders, MTG, Maxwell Textbooks, NYC Tunnels, Bohemian Grove, Shirley 02:38:34 – Kash Patel Lawsuit, Palantir, 9/11, Taliban Pros, 0pium War Reversal, Mexico Relations 02:49:13 – We're Screwed Either Way, Opioids, Narcan, Harm Reduction, Ethereal Economy 03:04:15 – Wage Stagnation, Dating Crisis, MAID Canada, Sarco Pod, Man in the High Castle 03:07:21 – Tyler's work CREDITS: - Host, Editor & Producer: Julian Dorey - COO, Producer & Editor: Alessi Allaman - https://www.youtube.com/@UCyLKzv5fKxGmVQg3cMJJzyQ - In-Studio Producer: Joey Deef - https://www.instagram.com/joeydeef/ Julian Dorey Podcast Episode 363 - Tyler Oliveira Music by Artlist.io Learn more about your ad choices. Visit podcastchoices.com/adchoices

Jonathan Jones, author of "Opium Slavery: The Civil War, Veterans, and Americas First Opioid Crisis"

Today from SDPB - the Department of Social Services and the Attorney General's office are at odds over how opioid settlement dollars should be used, some schools facing financial sanctions receive their fate from legislators and a look at overdose deaths in the state's prison system.

During the Civil War, the utility and widespread availability of opium and morphine made opiates essential to wartime medicine. After the war ended, thousands of ailing soldiers became addicted, or “enslaved,” as nineteenth-century Americans phrased it. Veterans, their families, and communities struggled to cope with addiction's health and social consequences. Medical and government authorities compounded veterans' suffering and imbued the epidemic with cultural meaning by branding addiction as a matter of moral weakness, unmanliness, or mental infirmity. Framing addiction as “opium slavery” limited the efficacy of care and left many veterans to suffer needlessly for decades after the war ended.  Drawing from veterans' firsthand accounts as well as mental asylum and hospital records, government and medical reports, newspaper coverage of addiction, and advertisements, in Opium Slavery: Civil War Veterans and America's First Opioid Crisis (UNC Press, 2025) Dr. Jonathan S. Jones unearths the poorly understood stories of opiate-addicted Civil War veterans in unflinching detail, illuminating the war's traumatic legacies. In doing so, Jones provides critical historical context for the modern opioid crisis, which bears tragic resemblance to that of the post–Civil War era. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda's interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

David Segraves is the founder of Elite Pain Doctors, an interventional pain management group that provides non-opioid solutions for chronic pain sufferers.. Growing up in an Indiana town crippled by the opioid epidemic, David shares his personal struggles and subsequent triumph in creating a business model dedicated to offering non-opioid pain relief. Through strategic partnerships with medical experts and leveraging imaging technology, Elite Pain Doctors provide sustainable solutions for patients.The discussion extends to explore the sociocultural and economic factors contributing to the pervasive opioid crisis, particularly in the Midwest. David describes the systemic issues within the pharmaceutical industry and emphasizes his approach of radical transparency in patient care. His story is a testament to resilience and innovation in healthcare, as he expands his business model nationwide to tackle opioid dependency. Furthermore, David touches on the unique interdisciplinary nature of his practice, combining various healthcare professionals to ensure comprehensive pain management.Key Takeaways:Transformative Business Model: Elite Pain Doctors emphasize non-opioid pain relief solutions, making significant strides in chronic pain management.From Personal Struggle to Solution Provider: David's journey from an opioid-affected community to a healthcare innovator shows resilience and determination.Nationwide Expansion: Plans are in place to grow the model nationally, advocating for policy changes to support innovative pain management techniques.Interdisciplinary Approach: The incorporation of diverse medical professionals ensures holistic patient care and improved outcomes.Advocacy and Transparency: Radical transparency in interactions and educating patients on their treatment options is pivotal for patient empowerment and trust.Notable Quotes:"We're changing lives that way. We find exactly what is wrong with the person and then do a procedure to get them out of pain.""I grew up in a small town, Indiana, that was very much affected by the opioid epidemic and had my own struggles with that.""The community I grew up in is what I would say, we used to joke about our high school and call it the pharmacy.""It's a terrible situation, and when you get into those situations, it's gone so far.""We're taking this thing nationwide...a model that should be adopted by every state, especially the ones that had opioid epidemics."Connect with David Segraves:WebsiteInstagramElite Pain DoctorsConnect with Rudy Mawer:LinkedInInstagramFacebookTwitter

In this gripping episode of the Medical Sales Podcast, Samuel sits down with Jennifer Jones, a former top Purdue Pharma rep who lived through one of the most turbulent eras in pharmaceutical history. Jennifer recounts her shocking personal encounters with the FBI, the emotional strain of grand jury testimony, the collapse of Purdue from the inside, and the complicated reality reps faced far beyond the headlines. She shares raw stories of ethical dilemmas, patient advocacy, "pill mill" misconceptions, and the unseen pressures of pain management in the 2000s. Jennifer then opens up about rebuilding her life and identity after Purdue's shutdown, scaling a thriving wine business, launching a coaching company, and ultimately returning to medical device sales where she now leads in cardiology. This conversation delivers rare honesty about pharma, entrepreneurship, career reinvention, and what it truly takes to survive, grow, and lead in medical sales today.   Connect with Jennifer Jones: LinkedIn Connect with Me: LinkedIn Love the show? Subscribe, rate, review, and share! Here's How »

In this episode, James Campbell, MD, MS, FAAP, discusses the AAP's updated recommendations for COVID-19 vaccines in infants, children and adolescents. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Scott Hadland, MD, MPH, MS, FAAP, about the use of buprenorphine for the treatment of opioid use disorder in young people. For resources go to aap.org/podcast.

As read by George Hahn. https://www.profgalloway.com/the-next-opioid-crisis/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

In our news wrap Friday, a federal bankruptcy judge will approve Purdue Pharma’s latest deal to settle lawsuits over the damage of opioids, Charlotte is bracing for an expected surge of federal agents as President Trump looks to expand his immigration crackdown and the Trump administration is dropping plans to make airlines compensate passengers for flight delays caused by carriers. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy