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Somagen Method of Alcohol Reagent Tracking (SMART) Optimization to Realize Workflow Efficiencies within the Laboratory-Anne de Wolf, BSc MLT Somagen Diagnostics, Edmonton, Alberta, Canada; Christine Chiu MLT Somagen Diagnostics, Toronto, Ontario, Canada; Annie Vallee Somagen Diagnostics, Montreal, Quebec, Canada; James Tang, BSc MLT Somagen Diagnostics, Edmonton, Alberta, Canada Tissue processing in recent decades has changed without subsequent changes to reagent maintenance. Reagent maintenance protocols have been ‘Grandfathered down' without consideration for the reagent quality and how this is related to tissue types and block numbers processed. The concentration of the last absolute alcohol station needs to be >98 % to effectively remove water from tissue before clearing and paraffin infiltration.1, 2 Using the Eagle Eye Digital hydrometer can provide reagent quality information which could also provide potential downstream efficiencies to laboratory workflow and cost savings in labour and reagents.
The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins.In this episode we talk with three experts about how this animal's unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall.Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/
Cameron and Dave discuss the dead brought back to life in horrifying ways, in Re-Animator (1985) vs the original H.P. Lovecraft short story, Herbert West - Reanimator (1922). Music by Jake Lionheart Contact: www.monsterdear.monster @senplus.bsky.social @drfaustisdead.bsky.social @theuglymachine.bsky.social @swarbie.bsky.social
This is a story of a 6 year old all girl advanced tball team called the Glitter Unicorns. One that went nationwide and it all started in our little South Walton county. What would you do if you got a text like the one we spoke about on today's episode? Please share this out and let us know what you would have done
The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins.In this episode we talk with three experts about how this animal's unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall.Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/
How bad are your reagents?Send us your questions to TalkingPools@gmail.com Support the show
Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/The horseshoe crab has endured for over 450 million years. It has survived several mass extinctions including the one that killed off the dinosaurs. One reason for their incredible resiliency is their ability to fend off bacterial infection. Their blood contains cells that clot around invading bacteria, thereby protecting them from the attacking toxins.In this episode we talk with three experts about how this animal's unique blue blood has become essential to modern medicine. We also talk about why horseshoe crab populations are dwindling, and what biotech is doing to address the shortfall.
Dr Julian Grümmer's NODES 2022 talk: https://www.youtube.com/watch?v=7JfXoubUv3QKnowledge Graph 101: What Is It, How it Works, & Why It Matters: https://neo4j.com/blog/what-is-knowledge-graph/Building Knowledge Graphs: A Practitioner's Guide: https://neo4j.com/knowledge-graphs-practitioners-guideKnowledge Graphs & LLMs: Multi-Hop Question & Answering: https://neo4j.com/developer-blog/knowledge-graphs-llms-multi-hop-question-answering/Knowledge Graphs & LLMs: Fine Tuning vs Retrieval Augmented Generation: https://neo4j.com/developer-blog/fine-tuning-retrieval-augmented-generation/LangChain Cypher Search: Tips & Tricks: https://neo4j.com/developer-blog/langchain-cypher-search-tips-tricks/Hot Algo Summer: New Algorithms in Neo4j Graph Data Science: https://neo4j.com/developer-blog/hot-algo-summer-gds/Time Machine: A look-back at Java Sessions at Nodes: https://neo4j.com/developer-blog/java-sessions-nodes-2022/Building Java Applications with Neo4j: https://www.javacodegeeks.com/2023/07/pouring-coffee-into-the-matrix-building-java-applications-on-neo4j.htmlUsing Spring for GraphQL With Spring Data: https://neo4j.com/developer-blog/spring-graphql-neo4j/Python driver updates: https://github.com/neo4j/neo4j-python-driver/wiki/5.x-changelogNeomodel (community Python OGM) updates: https://github.com/neo4j-contrib/neomodel/releases/tag/5.1.0Mock data generator 0.1.0 released as a Pypi package: https://pypi.org/project/graph-data-generator/neo4j-balena: https://github.com/mpous/neo4j-balenaNeodash updates: https://github.com/neo4j-labs/neodash/releases/tag/2.3.0Exploring Neodash for 197M Chemical Full-Text Graph: https://neo4j.com/developer-blog/exploring-neodash-for-197m-chemical-full-text-graph/How to Implement SSO for your Neo4j Instance: https://neo4j.com/developer-blog/implement-sso-neo4j-auth0/New Sandbox Feature: Single Sign-On: https://neo4j.com/developer-blog/neo4j-sandbox-sso/Entity Resolution in Reagent: https://margin.re/2023/06/entity-resolution-in-reagent/Neo4j GraphQL Toolbox: https://graphql-toolbox.neo4j.io/Updated GraphAcademy Course: Introduction To Neo4j & GraphQL: https://graphacademy.neo4j.com/courses/graphql-basics/Pomodoro App: https://pomofocus.io/Spring Boot: https://spring.io/projects/spring-bootCody.ai by Sourcegraph: https://docs.sourcegraph.com/codyCodiumAI: https://www.codium.ai/Arxiv.org: https://arxiv.org/
Empower your customers to achieve unprecedented success in water management by adopting a comprehensive approach that goes beyond boilers and chillers. Embrace the holistic potential of water management, including irrigation systems, and witness remarkable water savings. Today, we have the privilege of hosting the brilliant Andy Humphrey, a seasoned Irrigation Technology Consultant from Sprinkler Supply Store. Join us as we explore the future of irrigation, delve into the intrinsic value of water, discuss e-commerce in the B2B and D2C sectors, unravel the process of creating a water budget, and examine the latest advancements in irrigation technology. Furthermore, we will examine the advantages and disadvantages of reusing water runoff, the significance of enhanced sensors and data analytics, the influence of Andy's own podcast, the importance of establishing a positive and educational online presence, and gain insights from his experience as a guest on Shark Tank. Bottom line: when it comes to water savings for our customers, it is crucial to emphasize that it encompasses more than just their boilers and chillers. We must encourage them to think innovatively and expand their focus on every aspect of water usage. By embracing irrigation technology, we can collectively contribute to the conservation of billions of gallons of fresh water daily. Together, let's make waves and pave the way for a sustainable future. Timestamps Trace Blackmore galvanizes you to be the very best heat transfer efficiency manager [1:00] Upcoming Events for Water Treatment Professionals [8:30] Interview with Andy Humphrey, Irrigation Technology Consultant [14:00] Periodic Water Table With James McDonald [01:03:05] Quotes “We undervalue water. There are low-hanging opportunities to reduce water usage that doesn't take a lot of technology, yet we still let it happen.” - Andy Humphrey “I saw how we were using water in the irrigation industry and decided to go headfirst into the irrigation industry with technology both in the hardware and software side.” - Andy Humphrey “Rain: money falling from the sky. When water is falling you should not be irrigating.” - Andy Humphrey “There's only so much water the soil can use.” - Andy Humphrey “We need to make money AND we need to be able to have margin in order to make customers happy.” - Andy Humphrey “You get better the more you do it. You just have to start and try something new.” - Andy Humphrey “We are heat transfer efficiency managers, everything we do is about heat transfer.” - Trace Blackmore “Talk about your value with your clients. Show them how much money your work saves them.” - Trace Blackmore Connect with Andy Humphrey Phone: 208-908-3229 Email: andyhum@gmail.com Website: SprinklerSupplyStore.com Podcast: The Sprinkler Nerd Show Sharktank: https://www.sharktankblog.com/business/ecomowers/ LinkedIn: in/andyhum/ YouTube: @Andy_Humphrey Read or Download Andy Humprey's Press Release HERE 2023 Events for Water Professionals Check out our Scaling UP! H2O Events Calendar where we've listed every event Water Treaters should be aware of by clicking HERE or using the dropdown menu. Periodic Water Table With James McDonald Some of you may be thinking I made this one up, but no, I haven't. Fenton's Reagent. What is it? What chemicals are involved in the Fenton reaction? What are the chemical reactions happening? When and where would one use Fenton's Reagent? What dosage ratios between components are recommended? Do low and high pH have an impact upon the reaction? Conversely, will Fenton's Reagent have an impact upon water pH? What is a hydroxyl radical and how is that different from the hydroxide ion?
Gaining trust is important, both in our daily lives and in the laboratory. But how do we build trust in science? In our research? Join us as we delve into the world of scientific reproducibility and explore how common laboratory tools may be hindering progress. Professor Pierre Cosson shares his expert insights with Joshua on the state of science today and reveals how the development of recombinant antibodies could be the game-changer we've all been waiting for. If you're ready to be on the cutting-edge of scientific discovery and learn how to build trust in your research, then don't miss out on this episode of Biosounds! Introduction by Davide D'Amico.
Kamu gamau nikah? karena takut gabisa berkarya lagi karena harus berkorporat dan mengurusi keluarga? Nah ini nih, ketika sudah berkeluarga, agar finansial aman ya kerja, agar tetep waras ya berkarya, biar seimbang semuanya. Cuman, caranya gimana yaa? nyeimbangin kerja sama ngarya aja sudah repot, ini ditambah berkeluarga. anak istri gimana nih nanti? nah ini nih sedikit tips untuk teman-teman, apalagi tau lah ya cukup sulit untuk menjadikan hip-hop ini sebagai mata pencaharian utama. 'cuz we do this fo tha love y'all. dengerin yak, bersama Reagent dan Racil, dua Graffiti Artist ini yang justru ketika sudah berkeluarga dan punya anak, justru makin aktif berkarya. --- Support this podcast: https://podcasters.spotify.com/pod/show/hiphoptalk/support
Do you know how endotoxin tests are carried out? Well, in this interview with David Guy from Cape Code Associates, you'll find out ! David tells us about recombinant reagents, a new technology that aims to replace LAL (Limulus amebocyte lysate) and stop using horseshoe crabs, these prehistoric animals whose blood contains the precious enzymes necessary to perform these famous tests!
TRUE LOVE is one of few things that can ever be converted into FAKE. Care is a REAGENT. And sometimes, this LOVE BECOMES THE PERFECT PRISON... Check out "TRUE LOVE?" now by clicking or copying this link below
Muskegon History and Beyond with the Lakeshore Museum Center
On our podcast today we tell the story of the man who created the Strand, Reagent, and Michigan (now Frauenthal) theaters. His love of the theater lead to a local theater empire in Muskegon County and brought him much success. Today we tell the story of the man commonly called P.J. --- Support this podcast: https://anchor.fm/patrick-horn/support
This is not a which is the best type of podcast but I answer which one to use and when more or less. I also go over the pros and cons of each of these testing ethods for you.Leslie's Pro: Pool Service Pro, open a Wholesale account today! Customer referrals, free cleaner repairs, free water testing, open 7-days a week. It is fast and easy to become a Leslie's Preferred Pool Care Provider. https://lesliespool.com/commercial-services.html/?utm_medium=referral&utm_source=spll&utm_campaign=spll
Furkan on Twitter - https://twitter.com/furkan3ayraktar Furkan on GitHub - https://github.com/furkan3ayraktar Scrintal - https://www.scrintal.com Scrintal's story explained in Scrintal - https://beta.scrintal.com/b/final-scrintal- board--jtult Polylith - https://polylith.gitbook.io/polylith/ Polylith is a software architecture that applies functional thinking at the system scale. It helps us build simple, maintainable, testable, and scalable backend systems. Datomic Cloud - https://docs.datomic.com/cloud/ A transactional database with a flexible data model, elastic scaling, and rich queries. Reagent - https://github.com/reagent-project/reagent A ClojureScript wrapper around React. Re-frame - https://github.com/day8/re-frame Frontend framework that provides events for writes and subscriptions for reads. Datascript - https://github.com/tonsky/datascript/ An immutable in-memory database and Datalog query engine in Clojure and ClojureScript. Prosemirror - https://prosemirror.net A toolkit for building rich-text editors on the web KonvaJS - https://konvajs.org HTML5 canvas library for desktop and mobile applications Posh - https://github.com/denistakeda/posh Use Datascript to store application state Re-posh - https://github.com/denistakeda/re-posh Use Posh with re-frame subscriptions and events Firestore - https://firebase.google.com/docs/firestore Scalable NoSQL cloud database to store and sync data for client- and server-side development. stitches - https://stitches.dev CSS-in-JS with near-zero runtime, SSR, multi-variant support, and a best-in-class developer experience. shadow-cljs - https://github.com/thheller/shadow-cljs everything you need to compile your ClojureScript code with a focus on simplicity and ease of use.
Chuck began his career in the automotive industry as an engineer, new product implementation project manager, continuous improvement leader and manager while simultaneously operating a residential redevelopment company. He joined his wife Janet full-time as a PA licensed Realtor in 2018, helping people get what they want. He specializes in providing clients with options to achieve their real estate goals. Janet has a life long career in sales and found her passion in Real Estate when she became a licensed Realtor in 2005. She integrates both buyer's and seller's perspectives in each transaction while helping them achieve their goals. Networking and helping women in business connect is extremely important to her since moving to Lancaster 10 years ago. Together with Chuck, they founded the Rockstar Connect Lancaster Networking group to bring business owners, entrepreneurs, professionals and success minded individuals together to form beneficial relationships. Her focus on supportive women in business led her to a coordination role for the Red Rose Coffee Connections women's networking group in 2021. Chuck & Janet's mission is to show you the possibilities for living a better lifestyle, and help you get what you want in Lancaster County, PA. Matching Lancaster was born out of the desire to show the world what it's like to live in Lancaster, PA. Their vision is to be the trusted resource for people looking to improve their living situation in Lancaster, PA.
Understanding Risks, Tradeoffs, and Prioritization in Your Next Automated Assay Development Program:1. Product StrategyWorking backwards from the commercial goal, the purpose is to understand key drivers of product architecture and identify technical risk. Driving decision-making throughout development: intended price target and use case.2. Ease of UseIdentify which areas of the eventual product are most valuable to automate, and which are better left as manual user steps. Understand the risks and tradeoffs between the complexity of automation and the likelihood of human error.3. Sensitivity AnalysisBreak down assay steps and establish clear technical requirements for each step, as well as their interdependencies. Allow the engineering team to know what variables need further study to accurately assess technical risk.4. Consumable/Durable InterfaceFocus on device functionality and where features will reside in the system: what belongs on the cartridge and what belongs on the instrument to achieve performance and system requirements?5. Reagent HandlingConsider how reagents will be introduced to the assay: through durable containers at large runs or on the consumable in small doses. Reagent handling dictates high-level architecture decisions, best addressed early for optimal product architecture.6. Fluidic ControlPrecise liquid handling is a core challenge in assay automation. Identify how liquids, and typically air, will be controlled in a reliable, repeatable way, consider automation solutions for fluidics control, and address contamination sensitivity.7. Temperature ManagementDevelop methods for measuring and controlling temperature by understanding the effects on the instrument, cartridge, and assay performance.8. Algorithm DevelopmentThe data processing algorithm is often the core value proposition and differentiator being brought to market. Two factors ensure a clinically actionable test result: understanding the limits and constraints of the algorithm and recognizing the instrument requirements that the algorithm demands.9. Tech De-Risking MethodsIdentify what risks need to be mitigated and where various de-risking methods should be deployed. Methodology options include creating testbeds, modeling and simulation, and subcomponent specialist consulting.10. ScaleThe framework bookend considers the impacts of high quantities and long-term use on the instrument and cartridge reliability, cost, and performance. Understand whether the device can work in large numbers and what strategies should be employed to improve reliability and performance while containing cost.
Every year I have a tradition of choosing ten targets for the year. After coaching this for the past 5+ years, here are the top 5 things that I have discovered that if you avoid them, can create a phenomenal and fun year! IN THIS EPISODE, I TALK ABOUT:How my experience at a fast food restaurant pushed me out energetically.How learning and saying someone's name can get you into a state of presence.The question, “How are you?” can be stale and overused that we become zombies and tune out when we ask it. CLASSES:If you're interested in creating your life AND generating REAL change and potency in 2022, I invite you to join my CREATE YOUR LIFE “Annual Planning Workshop” in January 2022. Text: CREATE to 323-524-9857 to learn about our future dates. RESOURCES:Text: CREATE to 323-524-9857 to apply for my Get Up Girl Gang community If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser and Castbox. Let's Connect:The Get Up GirlInstagramFacebookMonthly online fitness academy
Couple original songs ... more to come soon
00:00 - Intro01:11 - Things can go wrong in water testing, so let's review the common mistakes and interferences.05:07 - Reagent expiration dates mean nothing if the kit is not stored properly. All test kits have a finite shelf life.09:10 - Bleaching reagents (very high chlorine) can distort other tests too.15:08 - Cold water interferes with accuracy too. Warm the sample before testing.18:48 - Mistakes are common when collecting a sample and taking it somewhere. Grab the sample from below the water surface, fill the clean bottle completely without a big pocket of air in it, and then take it directly to the pool store or lab. The longer you wait, the less accurate the test results.23:29 - A few other items: lighting is important for color comparison tests, and if you notice something is way off, test again and examine your test kit for problems. Practice, practice, practice.26:49 - Summary. Thanks for listening! ------------------------------------Connect with Orenda TechnologiesWebsite: https://www.orendatech.comBlog: https://blog.orendatech.comYouTube: https://www.youtube.com/user/OrendaTechnologiesFacebook: https://www.facebook.com/orendatech/Instagram: https://www.instagram.com/orendatechnologies/
There are really only four water testing methods available today for your pool and spa. Reagent test kits, photometers, digital testers, and test strips. I go over the pros and cons of each with Bob Lowry.Bob Lowry is the author of over 23 books but this has to be one of his most relevant and shortest books coming in at just 19 pages thick. But it is packed with so many essentials on residential pool chemistry that you will want a copy to carry in your service truck. Bob Lowry has been in the industry for over 47 years and is the Lead Consultant at Lowry Consulting Group, leads the Pool Chemistry Training Institute, and has created the Certified Residential Pool & Spa Certification Program. Learn more at https://pcti.online/Leslie's Pro: Pool Service Pro, open a Wholesale account today! Customer referrals, free cleaner repairs, free water testing, open 7-days a week. It is fast and easy to become a Leslie's Preferred Pool Care Provider. https://lesliespool.com/commercial-services.html/?utm_medium=referral&utm_source=spll&utm_campaign=spll
In this episode, supported by Roche, we explore a vital aspect of many next-generation sequencing studies: target enrichment. Here, regions of interest are selectively amplified before sequencing takes place. More specifically we examine some of the new technologies improving this key step and their impact on oncology research. My guest for this episode is Brian Godwin, Director of Reagent and Assay Development at Roche sequencing. Brian reveals the myriad of ways that poor target enrichment can impact a study while highlighting its importance at the foundations of many research efforts. Discover the key limitations of some target enrichment techniques and the new technologies that are improving this step, leading to a new suite of applications in oncology research, where damaged or degraded DNA samples are common. Listen today for an overview of the target enrichment process, the most exciting applications of this technique future potential of this step. Contents:Intro: 00:00-01:30Why conduct target enrichment? 00:40-02:45Established technologies for target enrichment: 02:45-04:10Challenges of working with these technologies: 04:20-06:40The impact of these challenges on sequencing results: 06:40-07:35New technologies to address these challenges: 07:35-09:25Primer extension in PCR and target enrichment: 09:25-11:40Exciting applications of primer extension target enrichment: 11:40-13:25Improving target enrichment in oncology and its impact on the field: 13:25-16:15If you could ask for one thing to enable primer extension target enrichment to make the greatest possible impact on the NGS and oncology communities, what would it be? 16:15-18:00
In this episode, supported by Roche, we explore a vital aspect of many next-generation sequencing studies: target enrichment. Here, regions of interest are selectively amplified before sequencing takes place. More specifically we examine some of the new technologies improving this key step and their impact on oncology research. My guest for this episode is Brian Godwin, Director of Reagent and Assay Development at Roche sequencing. Brian reveals the myriad of ways that poor target enrichment can impact a study while highlighting its importance at the foundations of many research efforts. Discover the key limitations of some target enrichment techniques and the new technologies that are improving this step, leading to a new suite of applications in oncology research, where damaged or degraded DNA samples are common.Listen today for an overview of the target enrichment process, the most exciting applications of this technique future potential of this step.Contents:Intro: 00:00-01:30Why conduct target enrichment? 00:40-02:45Established technologies for target enrichment: 02:45-04:10Challenges of working with these technologies: 04:20-06:40The impact of these challenges on sequencing results: 06:40-07:35New technologies to address these challenges: 07:35-09:25Primer extension in PCR and target enrichment: 09:25-11:40Exciting applications of primer extension target enrichment: 11:40-13:25Improving target enrichment in oncology and its impact on the field: 13:25-16:15If you could ask for one thing to enable primer extension target enrichment to make the greatest possible impact on the NGS and oncology communities, what would it be? 16:15-18:00 See acast.com/privacy for privacy and opt-out information.
In this video we'll be helping you decide which way a reaction will go with certain conditions (SN1, SN2, E1, and E2) Timestamp: (0:49) - Nucleophilicity and Basicity (rows) (1:13) - Nucleophilicity and Columns (2:00) - Reagent acting as nucleophile only (2:25) - Reagent acting as a strong base only (2:44) -Reagent acting as strong base / strong nucleophile (3:20) -Reagent acting as weak base/ weak nucleophile (3:47) -Reagent acting as nucleophile only (primary or secondary substrate) (4:09) -Reagent acting as nucleophile only (tertiary substrate) (4:20) -Reagent acting as a strong base only (primary, secondary, or tertiary substrate) (4:39) -Reagent acting as strong base / strong nucleophile (primary substrate) (5:04) -Reagent acting as strong base / strong nucleophile (secondary substrate) (5:13) -Reagent acting as strong base / strong nucleophile (tertiary substrate) (5:28) -Reagent acting as weak base/ weak nucleophile (primary or secondary substrate) (5:36) -Reagent acting as weak base/ weak nucleophile (tertiary substrate) (6:00) -Regiochemistry/Stereochemistry for SN1 (6:13) -Regiochemistry/Stereochemistry for SN2 (6:22) -Regiochemistry/Stereochemistry for E1 (6:29) -Regiochemistry/Stereochemistry for E2
Cheers to the 14th trip around the sun of the language that’s made up of data! In this episode, Esko, Matti and Toni discuss Clojure, REPL, and how you can use them in your next project.GuestsMatti Lankinen’s programming career started from the little boy's dream of making his own games. C++ was too hard at the time, so he started making his own programming language. It was never finished. (Hands up, who can relate?)Toni Vanhala learned the alphabet by typing on the keyboard and copying BASIC programs his mother read aloud. A couple decades later, Toni got his Ph.D. after programming a custom gaze tracker, virtual humans that react to facial expressions, and a chair that senses emotions.HostEsko Lahti is an engineer who now works in the company that got him into Clojure. Now, his party trick at meetups is to rapid fire through an extensive list of parentheses jokes.Episode linksThe Clojure programming language: https://clojure.org/Shadow CLJS: https://shadow-cljs.github.io/docs/UsersGuide.htmlLeiningen: https://leiningen.org/Pedestal: https://github.com/pedestal/pedestalclojurians.slack.com community (invite link): http://clojurians.net/Reitit, data-driven router for Clojure(Script): https://github.com/metosin/reititclj-kondo, a linter for Clojure: https://github.com/clj-kondo/clj-kondocljfmt, a tool for formatting Clojure: https://github.com/weavejester/cljfmtHiccup, a library for representing HTML in Clojure: https://github.com/weavejester/hiccupIntegrant: https://github.com/weavejester/integrantCursive, the Clojure(Script) IDE: https://cursive-ide.com/Nightlight, an embedded editor for Clojure: https://sekao.net/nightlight/Reagent, React for ClojureScript: https://reagent-project.github.io/re-frame, a ClojureScript framework for UIs: https://github.com/day8/re-frameRich Hickey’s most influential talks: https://changelog.com/posts/rich-hickeys-greatest-hitsAbout ReaktorFork Pull Merge Push is a podcast by Reaktor, a strategy, design and technology company changing how the world works. Reaktor has offices in New York, Amsterdam, Stockholm, Tokyo and Helsinki, Turku and Tampere.Reaktor is always on the lookout for bright software developers to work in health, security, emerging technologies, and much more.See www.reaktor.com/careers.@ReaktorNow#FPMPod
Welcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Thomas, is covering with us the usages of APTT testing. Literature sources: Toulon, P., Eloit, Y., Smahi, M., Sigaud, C., Jambou, D., Fischer, F. and Appert‐Flory, A. (2016), In vitro sensitivity of different activated partial thromboplastin time reagents to mild clotting factor deficiencies. Int. Jnl. Lab. Hem., 38: 389-396. https://doi.org/10.1111/ijlh.12499 CLSI One-stage Prothrombin Time (PT) test and Activated Partial Thromboplastin Time (APTT) test; Approved guideline - second edition. CLSI document H47-A2 Wayne, PA: Clinical and Laboratory Standard Institute, 2008 Levy JH, Szlam F, Wolberg AS, Winkler A. Clinical use of the activated partial thromboplastin time and prothrombin time for screening: a review of the literature and current guidelines for testing. Clin Lab Med. 2014 Sep;34(3):453-77. doi: 10.1016/j.cll.2014.06.005 Kitchen S, Jennings I, Woods TA, Preston FE. Wide variability in the sensitivity of APTT reagents for monitoring of heparin dosage. J Clin Pathol. 1996 Jan;49(1):10-4. doi: 10.1136/jcp.49.1.10. Gosselin RC, King JH, Janatpour KA, Dager WE, Larkin EC, Owings JT. Comparing direct thrombin inhibitors using aPTT, ecarin clotting times, and thrombin inhibitor management testing. Ann Pharmacother. 2004 Sep;38(9):1383-8. doi: 10.1345/aph.1D565. Gouin-Thibaut I, Martin-Toutain I, Peynaud-Debayle E, et al. Monitoring unfractionated heparin with APTT: a French collaborative study comparing sensitivity to heparin of 15 APTT reagents. Thrombosis Research. 2012 May;129(5):666-667. DOI: 10.1016/j.thromres.2011.11.016. Triplett DA. Screening for the lupus anticoagulant. Ricerca in Clinica E in Laboratorio. 1989; 19-379-89 Denis-Magdelaine A et al; Sensitivity of sixteen APTT reagents for the presence of anticoagulant. Haemostasis 1995; 25:98-105/ Rozen L, Copette F, Noubouossie DF, Demulder A. Evaluation of three APTT reagents in a routine laboratory: toward a compromise. Clin Lab. 2013;59(7-8):921-4. doi: 10.7754/clin.lab.2012.120909 van Rossum, A.P., Vlasveld, L.T., van den Hoven, L.J.M., de Wit, C.W.M. and Castel, A. (2012), False prolongation of the activated partial thromboplastin time (aPTT) in inflammatory patients: interference of C‐reactive protein. Br J Haematol, 157: 394-395. https://doi.org/10.1111/j.1365-2141.2011.08990.x Gu, J.‐M., Ramsey, P., Evans, V., Tang, L., Apeler, H., Leong, L., Murphy, J.E., Laux, V. and Myles, T. (2014), Evaluation of the activated partial thromboplastin time assay for clinical monitoring of PEGylated recombinant factor VIII (BAY 94‐9027) for haemophilia A. Haemophilia, 20: 593-600. https://doi.org/10.1111/hae.12374 Hillarp A, Bowyer A, Ezban M, Persson P, Kitchen S. Measuring FVIII activity of glycopegylated recombinant factor VIII, N8-GP, with commercially available one-stage clotting and chromogenic assay kits: a two-centre study. Haemophilia. 2017 May;23(3):458-465. doi: 10.1111/hae.13168. Ezban M, Hansen M, Kjalke M. An overview of turoctocog alfa pegol (N8-GP; ESPEROCT® ) assay performance: Implications for postadministration monitoring. Haemophilia. 2020;26(1):156-163. doi:10.1111/hae.13897 Related podcasts: Ask Stago S1E11: UFH monitoring: APTT or Anti-Xa? https://www.podcastics.com/podcast/episode/11-%E2%80%93-monitoring-of-ufh-aptt-or-anti-xa-41033/ Ask Stago S1E13: The Lupus Anticoagulant Diagnosis work up: https://www.podcastics.com/podcast/episode/13-the-lupus-anticoagulant-diagnosis-work-up%C2%A0-54015/ ____________________________________________________________________________________________________________ Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.
Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Draga, will give you all her tips to have the perfect calibration.
This Week in Machine Learning & Artificial Intelligence (AI) Podcast
Today we’re joined by Jason Gauci, a Software Engineering Manager at Facebook AI. In our conversation with Jason, we explore their Reinforcement Learning platform, Re-Agent (Horizon). We discuss the role of decision making and game theory in the platform and the types of decisions they’re using Re-Agent to make, from ranking and recommendations to their eCommerce marketplace. Jason also walks us through the differences between online/offline and on/off policy model training, and where Re-Agent sits in this spectrum. Finally, we discuss the concept of counterfactual causality, and how they ensure safety in the results of their models. The complete show notes for this episode can be found at twimlai.com/go/448.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.31.274761v1?rss=1 Authors: Marinus, T., Fessler, A. B., Ogle, C. A., Incarnato, D. Abstract: Due to the mounting evidence that RNA structure plays a critical role in regulating almost any physiological as well as pathological process, being able to accurately define the folding of RNA molecules within living cells has become a crucial need. We introduce here 2-aminopyridine-3-carboxylic acid imidazolide (2A3), as a general probe for the interrogation of RNA structures in vivo. 2A3 shows moderate improvements with respect to the state-of-the-art SHAPE reagent NAI on naked RNA under in vitro conditions, but it significantly outperforms NAI when probing RNA structure in vivo, particularly in bacteria, underlining its increased ability to permeate biological membranes. When used as a restraint to drive RNA structure prediction, data derived by SHAPE-MaP with 2A3 yields more accurate predictions than NAI-derived data. Due to its extreme efficiency and accuracy, we can anticipate that 2A3 will rapidly take over conventional SHAPE reagents for probing RNA structures both in vitro and in vivo. Copy rights belong to original authors. Visit the link for more info
Dėl šešių milijonų eurų vertės reagentų pirkimų Specialiųjų tyrimų tarnyba pateikė įtarimus Pagalbos onkologiniams ligoniams asociacijos prezidentui Šarūnui Narbutui.Vyriausybės ekstremalių situacijų komisijos nutarimai.Kur bus naudojami EVT iškovoti milijonai Lietuvos ūkininkams?Eilės ligoninėse.Per pirmą šių metų pusmetį sulaikyti 9 mln. kontrabandinių cigarečių pakelių, kai pernai per visus metus buvo sulaikyta milijonu mažiau.Užsienio naujienos.Nevyriausybinės organizacijos „Baltijos aplinkos forumas” ir „Lietuvos ornitologų draugija” išplatino viešą kreipimąsi dėl Vyriausybės patvirtintų naujų Žuvinto biosferos rezervato nuostatų.Ved. Darius Matas.
Juho on twitter - https://twitter.com/JuhoTeperi Juho on github - https://github.com/Deraen Reagent Project - https://github.com/reagent-project/reagent Video Courses: www.learnreagent.com/ www.learnreframe.com/ www.jacekschae.com/
In this episode, Michael Osterholm, Director of the Center for Infectious Disease Research and Policy at the University of Minnesota and author of Deadliest Enemy: Our War Against Killer Germs, provides an overview on the COVID-19 pandemic in regards to what has happened to date, what we’ve learned about how the disease spreads, and his optimism and pessimism about what potentially lies ahead. Michael gives his take on the true case fatality rate, why it differs around the world, and which underlying conditions, such as obesity, impact risk of severe illness and death. We also discuss the outlook regarding vaccines, repurposed drugs/antivirals for treatment, and Michael’s growing concern about supply chain limitations with respect to drugs, vaccines, n95 masks, and testing kits. We discuss: Recapping the brief history of COVID-19 and what potentially lies ahead [2:15]; Some positive news about immunity and reinfection [10:45]; Case fatality rate—The challenge in finding the true rate, difference by country, and the impact of age, underlying conditions, and obesity [13:00]; What has to be true for less than 100,000 Americans to die from COVID-19? [24:30]; How do we best protect healthcare workers? [29:45]; Concerns about testing capability—Reagent shortfall and a supply chain problem [39:30]; Vaccines and antivirals—The outlook, timing, and challenges [47:45]; Long term health of survivors of COVID-19 [56:45]; The impact of comorbidities—Diabetes, obesity, and immunosuppressed patients [59:30]; Understanding R0 and how the disease spreads [1:01:30]; The challenge of forecasting with so many unknown [1:08:00]; What explains the difference in cases and fatalities in different parts of the world? [1:14:30]; Repurposed drugs/antivirals being considered for treatment options—any optimism? [1:16:45]; A parting message from Michael about what lies ahead [1:18:30]; and More. Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/michaelosterholm Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.
In this podcast, I go over the differences between a Reagent Tester a Photometer Tester and Pool & spa Test Strips. What are the pros and cons of each? Tune in to find out.Visit my Sponsors: Jobber: https://getjobber.com/im/pool/ Jobber's field service scheduling software and app is the best way to organize your service business. Quote, schedule, invoice, and get paid—all in one place. INYOPools: http://bit.ly/INYOpools Inyopools.com has been helping pool owners find the right pool parts since 2001. With over 50,000 pool parts in stock, order online today and have your parts delivered right to your door.
Шоу нотес Сабж: noria-clj Андрей Зайцев - Abstract Reconciliation Dan Abramov - Beyond React 16 Reagent - где все хорошо с identity, только поверх React WebRenderer Skia Graphics Library React-blessed - React pluggable TUI renderer группа hypothesis для аннотаций, картинка выпуска Послушал? Оставь отзыв На hardcode.fm hardcodefm@telegram + группа hardcodefm@facebook hardcodefm@vkontakte
This podcast is part of the 2018 NSH Symposium/Convention Poster Podcast Series. The lead presenter for this poster was Carmelo Lupo. To read the full abstract, visit the Block.
A Tale of a Helm, a Figure and Some Trees Hijinks and Horror Upon the High Seas This week the Party find a lost boat with a strange cargo... What lies aboard the strange boat? Who is this strange man that’s heading towards the ship? Why does he recognise Rivane? How Will they attempt to unveil the truth? And Where Will it Lead them? Also this week – Belry has Leg issues, Tensho Breaks more things & Rivane finally adds to her Reagent bag A Tale of Many, With Items and Mystery A Questionable Crown from druidic History A Figure from the Past & a Creature of question Both of which have an Strange aura, Open to Suggestion For this week we bring you a Thrice Tied Story Of Questionable terms The Drunken, The Deceitful & the Satchel Full of Worms Learn more at Penancerpg.com Come talk with us on Twitter or Facebook Listen on Google Play, Spotify, iTunes, Libsyn, Stitcher Support us on Ko fi and Patreon
The members of the team get lessons on the varied ranges of southern hospitality that exist on Columbia, South Carolina. Throwback spends over 10 hours locked in a small room being pressured by the Dragons into spying on his team, while the others get a taste of sweet tea and real coffee. Mmmmm… coffee... WEBSITE - http://www.complexaction.net/actualplay/ PATREON - patreon.com/complexaction. Patron submission credits: Icefyre / The Dragons - Robert McPherson Scorch - Eric da’MAJ Music - "Hope Subsumed" Prism Shard (soundcloud.com/prism-shard) "Electro (Sketch)" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 3.0 http://creativecommons.org/licenses/by/3.0/ Artwork by Ethan S Brewerton - https://www.ethansbrewerton.com/ LEGAL STUFF: The Topps Company, Inc. has sole ownership of the names, logo, artwork, marks, photographs, sounds, audio, video and/or any proprietary material used in connection with the game Shadowrun. The Topps Company, Inc. has granted permission to Complex Action to use such names, logos, artwork, marks and/or any proprietary materials for promotional and informational purposes on its website but does not endorse, and is not affiliated with Complex Action in any official capacity whatsoever.
Incorporating New Dyes to Simplify Panel Design: Accelerating Reagent Availability In this webinar you will learn how custom reagents can aid you in flow cytometry panel design—without long waits for generating these components. We will cover: How quality custom reagents in small sizes will make your panel design easier How you can receive these reagents fast and without traditional wait times for manufacturing How you can be confident that quality control is maintained for these custom reagents Incorporating New Dyes to Simplify Panel Design Dr. Jorg Ruhrer, Director of Research Reagents at BD Bioscience will take through how to overcome a major limitation in multicolor panel design for flow cytometry experiments—limited antibody-fluorochrome combinations. Join him in this webinar as he shows you how custom reagents provide increased options in your multicolor panel design. Flow cytometry continues to be a critical tool for the analysis, characterization, and isolation of single cells from a heterogeneous cell population. The rapid introduction of dyes based on Sirigen technology has dramatically increased the total number of parameters that can be analyzed simultaneously from a single sample. Using these dyes coupled with recent advancements in flow cytometers, it is now possible to probe more than 28 different fluorescence parameters simultaneously, allowing for a much deeper biological understanding of a sample. However, in spite of these advancements, one of the major limitations to designing optimal multicolor panels is the unavailability of many reagents and specificities in these new fluorochromes. To address this need, BD Biosciences has launched a new product line that will give scientists immediate access to hundreds and eventually thousands of new antibody/bright dye combinations. These new combinations will give the flexibility that you need to design a multicolor panel without compromising on results. Jorg will discuss how these quality reagents will enable easier panel design, resulting in robust high content panels that will generate quality data to drive ever deeper scientific discoveries.
Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 17/19
Mon, 15 Sep 2014 12:00:00 +0100 https://edoc.ub.uni-muenchen.de/19290/ https://edoc.ub.uni-muenchen.de/19290/1/Chhaganlal_Kajal.pdf Chhaganlal, Kajal
Maintaining long-term stability of analytical procedures is an important undertaking for clinical laboratories. This process typically includes comparison of current and new reagent lots through paired measurement of patient and control samples, with defined criteria for acceptance and rejection of the new lot.
Demonstration of the formation of methyl magnesium iodide