Podcast appearances and mentions of charles graeber

This Day in Legal History: American Bar Association FoundedOn August 21, 1878, the American Bar Association (ABA) was founded in Saratoga Springs, New York, by a group of 75 lawyers committed to advancing the legal profession in the United States. The ABA quickly became the nation's premier organization for attorneys, setting standards for legal education, ethics, and professional conduct. It played a crucial role in shaping American jurisprudence, advocating for legal reforms, and providing resources for continuing legal education. Over the decades, the ABA influenced significant legal developments, including the establishment of the Model Rules of Professional Conduct, which guide attorney ethics nationwide.However, from 2009 to 2019, the ABA saw a substantial decline in membership, reflecting broader challenges within the legal profession, such as the rising cost of legal education, the changing dynamics of legal practice, and competition from other professional organizations. Despite these challenges, the ABA remains a key player in the legal field, continuing to influence policy and uphold the standards of the profession. Its founding marks a pivotal moment in U.S. legal history, representing the formalization of efforts to unify and elevate the practice of law across the country.George Santos, a former U.S. congressman representing Queens and Long Island, has pleaded guilty to fraud and identity theft charges, agreeing to serve a minimum of two years in prison. U.S. Attorney Breon Peace highlighted that Santos' acceptance of mandatory prison time was a critical factor in finalizing the recent plea agreement. Originally charged with fabricating fundraising figures and falsifying extensive parts of his biography during his congressional campaign, Santos was expelled from Congress in 2023. The 36-year-old now faces a potential maximum sentence of 22 years, with sentencing set for February 7 by Judge Joanna Seybert. Despite pleading guilty to only two counts, Santos admitted wrongdoing in all 23 original charges, which may influence the severity of his sentence. Peace emphasized the significance of holding corrupt public officials accountable to maintain public trust in governmental institutions.Recent Supreme Court rulings have narrowed the scope of what constitutes bribery under federal law, impacting how prosecutors approach corruption cases. In June, the Court decided that accepting gratuities after performing an official act does not violate federal bribery statutes for state and local officials. Another ruling limited the application of honest services fraud charges to non-government individuals, further restricting prosecutorial avenues. These decisions present challenges for federal prosecutors, who must now navigate a more constrained legal framework when pursuing corruption charges. Despite these obstacles, prosecutors like Peace remain committed to holding public officials accountable by adapting their strategies within the revised legal boundaries. Understanding these Supreme Court decisions is crucial for comprehending the current landscape of political corruption prosecutions and the efforts required to secure convictions.Mandatory prison was key to George Santos deal, US prosecutor says | ReutersAnthropic PBC is facing a copyright lawsuit from authors Andrea Bartz, Charles Graeber, and Kirk Wallace Johnson, who allege that the company used pirated versions of their works to train its AI model, "Claude." The authors claim that Anthropic used an open-source dataset called The Pile, which included a subset known as "Books3" containing nearly 200,000 pirated books, including their own. Although Books3 was removed from The Pile in August 2023, older versions with the pirated content remain available. The lawsuit, filed in the U.S. District Court for the Northern District of California, accuses Anthropic of training its AI on this illegally obtained content instead of properly licensing it, likening the situation to a "modern-day Napster."The authors argue that Anthropic's actions harm their ability to earn a living by enabling users to generate text that would otherwise be paid for, thereby undermining the licensing market for copyrighted material. They pointed out that other AI companies, such as OpenAI, Google, and Meta, have struck licensing deals with content owners, highlighting a growing market for legally licensed training data. In a related issue, Anthropic is also being sued by eight music publishers for allegedly using its AI to reproduce song lyrics scraped from the internet. The authors' complaint criticizes Anthropic for claiming to be a public benefit company while allegedly causing significant harm to copyright owners.Anthropic Hit With Copyright Suit From Authors Over Flagship AIA bill passed by the U.S. Senate to add 66 new judges to federal district courts is projected to increase government spending by $349 million over the next decade, according to a report from the Congressional Budget Office (CBO). The bill, known as the JUDGES Act, represents the first significant expansion of the judiciary since 1990 and aims to alleviate the increasing caseloads and staffing shortages in several states, including California, Texas, and Delaware. The bill plans to gradually create these judicial positions, including 63 permanent and three temporary ones, starting in January 2025.The CBO estimates that $98 million of the total cost will cover the salaries and benefits of the new judges, which are constitutionally protected and not subject to congressional appropriation. The remaining $250 million will cover administrative costs, including court staff, facilities, security, and technology. Additionally, the bill mandates that the Government Accountability Office report on judges' caseloads and federal detention space needs, which would cost $1 million over the same period.Despite the projected costs, supporters of the bill, including lead sponsor Senator Todd Young, argue that the cost of inaction would be higher, as delays in the judicial system could deny citizens timely access to justice. The bill now awaits consideration in the U.S. House of Representatives.Bill to add 66 US judges would cost $349 mln over a decade, CBO says | ReutersA federal judge in Dallas has blocked the U.S. Federal Trade Commission (FTC) from enforcing its near-total ban on noncompete agreements, which was set to take effect in September. U.S. District Judge Ada Brown ruled that the FTC lacked the authority to implement the ban, describing it as "unreasonably overbroad without a reasonable explanation." This ruling, favoring the U.S. Chamber of Commerce and a Texas tax firm that challenged the ban, is a significant setback for the FTC. The decision contrasts with a prior ruling by a Pennsylvania judge who supported the FTC's authority.The FTC argued that noncompete agreements harm workers by restricting economic freedom, depressing wages, and limiting innovation, while employers claim they protect investments in employees. Currently, about 20% of U.S. workers are subject to these agreements. Although the FTC planned to use its authority to ban noncompetes as part of its mission to prevent unfair competition, Judge Brown's ruling could lead to an appeal, potentially to the conservative-leaning 5th Circuit Court of Appeals. The case is one of three ongoing lawsuits against the FTC's rule, with other cases pending in Florida and Pennsylvania.FTC Ban on Worker Noncompete Deals Blocked by Federal Judge (2)US judge strikes down Biden administration ban on worker 'noncompete' agreements | Reuters This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.minimumcomp.com/subscribe

Amy Loughren, the nurse who played the huge part in capturing serial killer Charles Cullen, joins Helen live from the USUS journalist and author of the book 'The Good Nurse' Charles Graeber shares too the process and challenges of digging all the information he neededFind out why nebulisers are NOT the best choice for asthma patients from Dr Andrew Ives Kelly Harvarde talks about summer readsAnd Dr Katrin Jan from the German Veterinary Clinic answers all your pet-related questions.See omnystudio.com/listener for privacy information.

Dr. Vinod Balachandran explains how he and his colleagues successfully treated pancreatic cancer with bespoke mRNA vaccines. Science journalist Charles Graeber says this could be cancer's “penicillin moment.” This episode was produced by Avishay Artsy, edited by Matt Collette, fact-checked by Laura Bullard, engineered by Michael Raphael, and hosted by Sean Rameswaram. Transcript at vox.com/todayexplained  Support Today, Explained by making a financial contribution to Vox! bit.ly/givepodcasts Learn more about your ad choices. Visit podcastchoices.com/adchoices

Steve Adubato sits down with Charles Graeber, Journalist & Author of The Good Nurse, to discuss one of the most prolific serial killers in American history, registered nurse Charlie Cullen. Otis Rolley, Head of Philanthropy and Community Impact at Wells Fargo, joins Steve Adubato to discuss economic improvement and their outreach efforts in the philanthropic […]

Episode 126:THE REAL GOOD NURSE w/ Special Guest (Amy Loughren, RN) | The Success Of Radiology Starts With You! | Yes! It is true! Les Jockeys are hanging out with the real deal GOOD NURSE! In  Episode 125, The Jockeys discuss the riveting new Netflix movie/documentary THE GOOD NURSE. Based off the of the New York Times bestselling book THE GOOD NURSE: A True Story of Medicine, Madness, and Murder by Charles Graeber. A true story of the hunt for one of the most prolific serial killer (Charlie Cullen) and the woman (Amy Loughren, RN) who helped capture him. This is a must listen! Straight from the mouth of the real Hero and Medical Professional. Because of her bravery, safeguards in hospitals were implemented so nothing like this can happen again. Let the Jockeys know what you think in the comments. You may get featured on a follow up episode.Buy Us A Drink!

Episode 125: THE GOOD NURSE WATCH PARTY | The Success Of Radiology Starts With You! The Jockeys Discuss the riveting new Netflix movie/documentary THE GOOD NURSE. THE GOOD NURSE starring academy award winning actress Jessica Chastain and academy award winning actor Eddie Redmayne. Based off the of the New York Times bestselling book THE GOOD NURSE: A True Story of Medicine, Madness, and Murder by Charles Graeber. A medical professional and a serial killer?! Come watch with The Jockeys! Let the Jockeys know what you think of the movie in the comments. You may get featured on a follow up episode.Link to: Nurse Amputates Patient's FootBuy Us A Drink!

This episode, we welcome Amy Loughren, a real life hero and a pivotal character in “The Good Nurse” which follows the real story of Charles Cullen, a prolific serial killer who killed possibly over a hundred patients in New Jersey and Pennsylvania before finally getting caught in the early 2000s, due in large part to her help. The movie is adapted from the 2013 book called "The Good Nurse: A True Story of Medicine, Madness, and Murder," by journalist Charles Graeber. Amy's story is now getting another look in the new Netflix series “Capturing the Killer Nurse.”

We start this week by reviewing Tobias Lindholm's true crime drama THE GOOD NURSE (1:54), about an ER nurse (Jessica Chastain) who discovers that her charming colleague (Eddie Redmayne) is secretly murdering their patients. The film misses some areas it could dig deeper into this real-life tragedy, but it's really well-acted and has a strong ensemble. Next, we cover Harry Bradbeer's ENOLA HOLMES 2 (22:17), a plainly named sequel that provides another engaging adventure for Enola Holmes (Millie Bobby Brown). It's a delightful romp that's still a lot of fun even if it's not quite as brisk as the first film. And in this week's Patreon exclusive audio, we talk about the winner of our Noirvember poll, Jane Campion's 2003 film IN THE CUT, starring Meg Ryan and Mark Ruffalo! For anyone who celebrated, we hope you had a Happy Thanksgiving!  Join Our Patreon Buy Spoilerpiece Merch

In this episode of You Can't Make This Up, we are talking about the Netflix documentary “Capturing the Killer Nurse" out now on Netflix. Host Rebecca Lavoie interviews director Tim Travers Hawkins and author Charles Graeber.Charlie Cullen was an experienced registered nurse, trusted and beloved by his colleagues at Somerset Medical Center in New Jersey. He was also one of history's most prolific serial killers, with a body count potentially numbering in the hundreds across multiple medical facilities in the Northeast. Based on the best-selling book The Good Nurse  and dramatized in the Netflix feature film starring Jessica Chastain and Eddie Redmayne  – “Capturing the Killer Nurse” reveals the twisted story behind Cullen's hidden spree of murders and how Cullen's horrific actions underscore an even bigger danger still lurking in our healthcare system.SPOILER ALERT! If you haven't watched “Capturing the Killer Nurse" yet, make sure to add it to your watch-list before listening on.

From the book by Charles Graeber, Eddie Redmayne plays Charles Cullen, the serial killer nurse who managed to kill so many people thanks to his compassionate ways and his ability to become invisible Tobias Lindholm, Eddie Redmayne – The Good Nurse #ZFF2022 was first posted on November 6, 2022 at 2:03 pm.©2015 "Fred English Channel". Use of this feed is for personal non-commercial use only. If you are not reading this article in your feed reader, then the site is guilty of copyright infringement. Please contact me at radio@fred.fm

From the book by Charles Graeber, Eddie Redmayne plays Charles Cullen, the serial killer nurse who managed to kill so many people thanks to his compassionate ways and his ability to become invisible The post Tobias Lindholm, Eddie Redmayne – The Good Nurse #ZFF2022 appeared first on Fred Film Radio.

From the book by Charles Graeber, Eddie Redmayne plays Charles Cullen, the serial killer nurse who managed to kill so many people thanks to his compassionate ways and his ability to become invisible The post Tobias Lindholm, Eddie Redmayne – The Good Nurse #ZFF2022 appeared first on Fred Film Radio.

From the book by Charles Graeber, Eddie Redmayne plays Charles Cullen, the serial killer nurse who managed to kill so many people thanks to his compassionate ways and his ability to become invisible The post Tobias Lindholm, Eddie Redmayne – The Good Nurse #ZFF2022 appeared first on Fred Film Radio.

From the book by Charles Graeber, Eddie Redmayne plays Charles Cullen, the serial killer nurse who managed to kill so many people thanks to his compassionate ways and his ability to become invisible The post Tobias Lindholm, Eddie Redmayne – The Good Nurse #ZFF2022 appeared first on Fred Film Radio.

From the book by Charles Graeber, Eddie Redmayne plays Charles Cullen, the serial killer nurse who managed to kill so many people thanks to his compassionate ways and his ability to become invisible The post Tobias Lindholm, Eddie Redmayne – The Good Nurse #ZFF2022 appeared first on Fred Film Radio.

Puxando o fio pela história real que deu origem ao filme, a coisa é mais ou menos assim:::Em dezembro de 2003, o enfermeiro americano Charles Edmund Cullen, conhecido como O Anjo da Morte, foi preso e condenado à prisão perpétua por ter provocado a morte de 29 pacientes que estavam sob os seus cuidados clínicos, por meio da superdose de medicamentos como morfina e insulina. Porém, durante 16 anos de trabalho, foi levantada a suspeita de que Cullen teria na verdade tirado a vida de aproximadamente 400 pessoas.::Essa história se tornou um livro chamado “The Angel of Death”, e é a partir dele que surgiu esse filme, que tem como roteirista Charles Graeber, justamente o autor do livro. A direção aqui é do dinamarquês Tobias Lindholm, que ainda engatinha na carreira de diretor mas que foi o responsável pelo roteiro de dois mega sucessos da dinamarca: os indicados ao Oscar "Druk" (vencedor) e "A Caça".::Entrando mais a fundo na história, nós acompanhamos o dia a dia da enfermeira Amy, vivida pela sempre competente Jessica Chastain. Ela trabalha no turno da noite de um hospital para poder criar, sozinha, duas filhas pequenas, com o agravante de sofrer sérios problemas cardíacos. E são nesses plantões que ela vai conhecer o enfermeiro Charlie (Eddie Redmayne), de quem vai ficar amiga íntima num primeiro momento, mas logo passará a desconfiar de suas atitudes bastante suspeitas. ::Coloque seu fone, aumente o volume e Senta que lá vem Spoiler!

Possibly the most prolific killer in American history. He didn't use a knife, or a gun. He used medication, and the hospital system. He killed people at their most vulnerable, and what makes this story so frightening is that anyone reading this could have been a victim of Charles Cullen if he was working at the hospital you were treated at. The Netflix film about this story, starring Oscar winners Eddie Redmayne and Jessica Chastain, written by 1917's Krysty Wilson-Cairnes, directed by Tobias Lindholm, is based on Charles Graeber's extraordinary, insanely well-researched book about Charles Cullen, this killer nurse who hid in plain sight. I was really anticipating this film. I'd love to hear your thoughts on it. Reach out at dan@voyagemedia.com, @watchthistonightpodcast (TikTok), @BenamorDan (Twitter), watch_this_tonight (Instagram) and please leave us a five star review on Apple Podcasts if you're enjoying the show.

Based on the book by Charles Graeber, The Good Nurse tells the story of Amy Loughren (Jessica Chastain), a compassionate nurse who begins to grow suspicious that her colleague Charlie Cullen (Eddie Redmayne) is responsible for a series of mysterious patient deaths. Over the past two months, Krista sat down separately with director Tobias Lindholm, Chastain, and Redmayne to discuss their experiences making the film. Today, we're weaving together those conversations to get a glimpse inside the incredible story and tireless work that fueled its creation.

Eddie Redmayne joins the show to talk about his role as Charles Cullen in Tobias Lindholm's chilling new thriller, The Good Nurse. Based on the book by Charles Graeber, the film follows Amy Loughren (Jessica Chastain), a compassionate nurse who begins to grow suspicious that her colleague is responsible for a series of mysterious patient deaths.Redmayne explains how he captured the physicality and essence of Cullen's character, shares what he's taking away from his experience working with Chastain, and describes witnessing Lindholm's incredible confidence and leadership on set.He also recounts how he was terrified of being fired while working on Robert De Niro's 2006 spy film, The Good Shepherd, reflects on his experience performing in Cabaret, and touches on his recent studies at Lecoq, a French theatre school in Paris.

It's a brand new case! Join us as we learn about Charlies horrific childhood and about the personality disorder Cortney believes he developed.  References: The Good Nurse by Charles Graeber. Wikipedia, Murderpedia

1/5/2022, Mike and co-host actress Mia Bella welcomed award-winning Canadian actress Alix West Lefler to ConversationsRadio Episode 117! Alix hails from beautiful Vancouver, B.C. This talented young actress discovered her love for performing, not in film or television but in extreme outdoor sports shows where she was featured as a log roller and an axe thrower at the age of 5. Yes - Axe Throwing! The acting bug bit Alix early! Her Career began on stage and it wasn't long before she got an agent and began booking roles on TV and film. Alex is well known for her roles as 'Juniper Cooper' on the CW series 'RIVERDALE' and 'Hope' on FREEFORM's 'SIREN.' Alix West Lefler Alix has appeared on ABC's 'The Good Doctor.' She has been featured Hallmark movies 'Chateau Christmas' and 'Cranberry Christmas' and booked a guest spot on the SYFY's 'Resident Alien.' In Spring, 2021, Alix traveled to Connecticut for 3 months to film the Netflix thriller 'The Good Nurse'. Alix stars opposite Academy Award-winning actor Eddie Redmayne and Academy Award-nominated actress Jessica Chastain. Based on the book by Charles Graeber, the film - directed by Tobias Lindholm is the true story of Charles Cullen - one of the most prolific serial killers in history who is suspected of murdering up to 400 patients during his 16-year career as a nurse, earning him the title 'The Angel of Death.' Look for Alix in 'The Good Nurse' - coming to Netflix this spring 2022. You can follow Alix on Instagram @alixwestlefler Enjoy the Podcast!

How bestselling author Charlie Graber cracked the silence of the most prolific serial killer in American history.

What is Charlie Cullen’s fate? Will justice be done?  Can one spot a potential 'Angle of Death' working at a hospital? What are the red flags that signal something may be “off” at a facility where you or your loved one is recovering? And, there are other male nurses who kill, and we will analyze these cases.  Did the law change after Charlie? Are we safer today? What happened to “Agent” Amy, the true Good Nurse, and our persistent detectives, Tim Braun and Danny Baldwin?  Listen and find out as Tara and Jill wrap up the loose threads of terrifying story of The Good Nurse!This trilogy of episodes and the book The Good Nurse by Charles Graeber deal with suicide. We can all help prevent suicide. The Lifeline provides 24/7, free and confidential support for people in distress, prevention and crisis resources for you or your loved ones, and best practices for professionals. Please call 1-800 273- TALK or 8255.

This week, Leah talks all about two true crime books for her mini! Titles mentioned: "Devil in the White City" by Erik Larson with readalike "In the Garden of Beasts" by the same author. Also, "The Good Nurse" by Charles Graeber. Check out books, movies, and other materials through the Milwaukee county library system: countycat.mcfls.org www.hoopladigital.com wplc.overdrive.com oakcreeklibrary.org

Episode 13 - The Good Nurse Part 2: Suspicions of Nurse Charlie Cullen are rising. But, the police have no leads, no evidence and no cooperation. What the police need is an insider, one who understands nursing-- AND Charles Cullen. Enter - Amy Loughren, RN, who throws life into the investigation into possibly many deaths involving many hospitals and one Angel of Death.The Good Nurse book and episodes deal with suicide. We can all help prevent suicide. The Lifeline provides 24/7, free and confidential support for people in distress, prevention and crisis resources for you or your loved ones, and best practices for professionals. Please call 1-800 273- TALK or 8255.

Epi 12- The Good Nurse by Charles Graeber, Pt 1 This true crime story is a chilling account that leave us asking how was this possible? Who is this nurse, Charles Cullen?  How does a nurse become a cold-blooded killer?  We follow this a Angel of Death across the wards of many hospitals, leaving far too many of bodies in his wake, so many, he wouldn’t know the actual number! Would anyone  act to stop the madness?  Would anyone call the police? The Good Nurse book and episodes deal with suicide. We can all help prevent suicide. The Lifeline provides 24/7, free and confidential support for people in distress, prevention and crisis resources for you or your loved ones, and best practices for professionals. Please call 1-800 273- TALK or 8255.   

Fauci is touting vaccines as the answer. Trump says Chloroquene is the cure. But what no one is talking about is the immune system and how to keep it healthy in this chaotic COVID19 pandemic! In this special episode of Corona-Pocalypse we talk to New York Times best-selling author Charles Graeber. We'll review his latest book 'The Breakthrough, Immunotherapy And The Race To Cure Cancer,' and how the importance of immunotherapy is relevant to the COVID19 pandemic, how the field of immunotherapy was founded on anecdotes, and ethics in journalisim. Nurses get 1 CE for listening click the link https://www.surveymonkey.com/r/295HWQB Thanks to our sponsor Sequels Revenge Podcast https://podcasts.apple.com/us/podcast/sequels-revenge/id1486897854 Throw us some bucks, and help support our cause! Venmo: @Nurses-Hypo Need consulting or have questions email: nursesandhypochondriacs@gmail.com

As we wrap up 2019, we would like to thank everyone who listened to the FYI — For Your Innovation podcast. We received incredibly positive feedback for our podcast show and had some truly amazing guests in the past year, ranging from world class geneticists to founders and CEOs. In this final episode of 2019, we put together a “greatest hits compilation” of our five most popular episodes.   1. On the Road to Full Autonomy with Elon Musk (EP11) Elon Musk talks about how his engineering background drives his decision making for Tesla and why he is so confident that Tesla will achieve full autonomy. On this podcast: Elon Musk, Tasha Keeney, Cathie Wood. (Listen to the Full Episode)   2. Immunotherapy and the Race to Cure Cancer with Charles Graeber (EP21) For decades cancer was something that was treated rather than cured. Author of the book The Breakthrough: Immunotherapy and the Race to Cure Cancer, Charles Graeber unpacks the history of immunotherapy, why it remained on the fringes for so long, and why cancer might become a manageable disease. On this podcast: Charles Graeber and James Wang (Listen to the Full Episode)   3. The Genomic Revolution with Prof. Dr. George Church (EP26) Professor George Church is one of the pioneers of modern genetics. We dive into the stage of genomics, next generation oncology, the security and regulation of genetic information, gene editing, and the increasing speed of the genomic revolution. On this podcast: George Church, Manisha Samy, Simon Barnett, and James Wang. (Listen to the Full Episode)   4. Wright's Law—Understanding Technology Cost Curves with Brett Winton (EP07) Brett Winton explains how Wright's Law makes simple and robust predictions about technology cost declines, and why it's at the center of ARK's research. On this podcast: Brett Winton and James Wang (Listen to the Full Episode)   5. Cerebras' Wafer Scale Engine AI Chip with CEO Andrew Feldman (EP37) Andrew Feldman, co-founder and CEO of Cerebras, joins us to discuss the Wafer Scale Engine, or WSE, an AI chip that is 50 times larger than the largest chips produced by Nvidia and Intel. On this podcast: Andrew Feldman and James Wang (Listen to the Full Episode)   We will be back in 2020 with new episodes and more exciting topics, because investing in innovation starts with understanding it. Until then, stay innovative!  

As we wrap up 2019, we would like to thank everyone who listened to the FYI — For Your Innovation podcast. We received incredibly positive feedback for our podcast show and had some truly amazing guests in the past year, ranging from world class geneticists to founders and CEOs. In this final episode of 2019, we put together a “greatest hits compilation” of our five most popular episodes.   1. On the Road to Full Autonomy with Elon Musk (EP11) Elon Musk talks about how his engineering background drives his decision making for Tesla and why he is so confident that Tesla will achieve full autonomy. On this podcast: Elon Musk, Tasha Keeney, Cathie Wood. (Listen to the Full Episode)   2. Immunotherapy and the Race to Cure Cancer with Charles Graeber (EP21) For decades cancer was something that was treated rather than cured. Author of the book The Breakthrough: Immunotherapy and the Race to Cure Cancer, Charles Graeber unpacks the history of immunotherapy, why it remained on the fringes for so long, and why cancer might become a manageable disease. On this podcast: Charles Graeber and James Wang (Listen to the Full Episode)   3. The Genomic Revolution with Prof. Dr. George Church (EP26) Professor George Church is one of the pioneers of modern genetics. We dive into the stage of genomics, next generation oncology, the security and regulation of genetic information, gene editing, and the increasing speed of the genomic revolution. On this podcast: George Church, Manisha Samy, Simon Barnett, and James Wang. (Listen to the Full Episode)   4. Wright’s Law—Understanding Technology Cost Curves with Brett Winton (EP07) Brett Winton explains how Wright’s Law makes simple and robust predictions about technology cost declines, and why it’s at the center of ARK’s research. On this podcast: Brett Winton and James Wang (Listen to the Full Episode)   5. Cerebras’ Wafer Scale Engine AI Chip with CEO Andrew Feldman (EP37) Andrew Feldman, co-founder and CEO of Cerebras, joins us to discuss the Wafer Scale Engine, or WSE, an AI chip that is 50 times larger than the largest chips produced by Nvidia and Intel. On this podcast: Andrew Feldman and James Wang (Listen to the Full Episode)   We will be back in 2020 with new episodes and more exciting topics, because investing in innovation starts with understanding it. Until then, stay innovative!  

CC* is a Registered Nurse and has a lifetime of expertise and wisdom from both sides of the health care dynamic - as a patient harmed by medical care, and as a nurse. (* “CC” is a pseudonym to protect her identity.) It is CC’s experience having a permanently damaged body from multiple medical errors that have motivated her to share her story of neglectful and abusive encounters with inept and egotistical physicians so that others are aware and can take steps to protect themselves. The medical error damage to CC was compounded by a health care system designed to respond to medical errors with mafioso tactics: deny and defend and denigrate. Nurse CC pulls no punches in telling the tragic truth of the power dynamics, push for profit, and the wholesale of humanity by the Medical Mafia.   SHOW NOTES Childhood Spinal Infection NB - some of these show notes are based on CC's preparatory notes. Those portions are CC's voice and are italicized. 0:05:00 Born in 1957 just north of Philadelphia to a white, middle class family. Grew up suburban, one of 4 children with a very tough childhood due to family dysfunction. I was extremely ill at age 6 with a spinal infection that resulted in extended hospitalization, inability to attend first grade for 1/2 the school year and confinement in a body cast and body brace for years. Despite many obstacles I was smart, had tenacity and fight that would both make me the awesome person I am today despite much suffering and societal disapproval. 0:06:05 Fought my way to be the first on either side of my family to put myself through college. I entered a collegiate nursing program in a religious institution where I hardly fit in but I had the ability, even by that point, to become a chameleon instinctually knowing how to acclimate to any environment I found myself in throughout my life. Once there, a new world opened up to me and I was on fire. 0:07:00 Began working in a hospital technical job in high school paying well and allowing me to support myself and finance my tuition, books, transportation with a small student loan. Became a RN in 1979. It was hell but I had only known hell all my life so I loved it. It felt normal. Drama, life and death, front seat row to people’s most intimate moments. However, I had empathy even at that point for any human’s suffering and this became more and more of a curse as I aged. 0:08:00 Of course I married, I was pretty, had a supervisory role within 18 months of graduation and by society’s yardstick I was doing quite well. Eventually I reluctantly had children which was interesting because I didn’t ever like children but succumbed to my husband’s wishes and that in and of itself is a miracle that I could only attribute to God. Once my first baby was born, I truly knew love for the first time in life. I wanted to be a full time Mom but this was not even a remote possibility. 0:09:30 CC chose to become a school nurse to be closer to her kids, but away from the life and death drama of ICU - CC had a 2nd child with many birth defects and she had to advocate for him - he'd be dead if she wasn't a good advocate.     Flouroquinlolones   0:11:30 When CC worked in ICU, flouroquinolones were not in common use - I have extremely hard scientific evidence that I was given Levaquin in 2002 during a surgery but that memory would never occur to me till my records had been destroyed due to laws allowing health care providers to destroy after 7 years. 0:12:30 CC was an emotional wreck after that surgery, crying all the time - when she returned to work she had a mean streak - she asked her surgeon friend for an antidepressant prescription, and that helped control her behavior. 0:13:30 In 2011, CC had bronchitis so just went to an urgent care clinic and was given Ciprofloxacin. 0:14:30 Prior to Cipro, I had been superwoman. I worked at times 3 jobs, obtained a Master’s degree and even a real estate license. So, because I was a school nurse and could be off for the summer which I never did, I remained in bed all summer. As September approached I called my internist to report this resulting in a few blood tests and being told I was just getting older. I had never been this age so I accepted this was normal. 0:16:00 CC's symptoms were extreme tiredness and weakness: she couldn't get out of bed - I drug myself to work, had been on an AD (antidepressants) since the surgery in 2002 which I knew when going back for my first post op visit I told my surgeon colleague, I’m mean. I need a SSRI, which sent me to a psychiatrist since that time. Of course all was attributed to my journey in life of mammoth stress and I happily took this which did allow me to continue at superwoman warp speed but in retrospect I had agitation and anxiety apparent but did not interfere with my ability to function. 0:18:00 CC says people in her situation are doubly traumatized when they realize they've been brain washed by the health care system she worked in - so they carry a lot of guilt as a health care worker. 0:20:00 By early 2012 I told my psychiatrist that I could barely get out of bed and he gave me a type of stimulant, not an amphetamine, called Provigil used for sleep apnea and MS (multiple sclerosis) fatigue. This allowed me to get through the work day, going to bed for a few hours at a time but I was able to earn money. 0:21:15 But I became pathetically agitated and no longer could physically be Mother Theresa as everyone knew me to be. I had anxiety to such a degree that if things were going poorly at work, I’d pick up the phone, say I was sick and had to flee on a few occasions. I knew something was wrong but I never associated the word anxiety, panic attacks to my situation. I was confused because I was being abused in the educational system but just performed at superhuman levels and now was saying no. They didn’t like that and labeled me a troublemaker and suspected of having mental health problems.   "Lamb being lead to slaughter"   0:23:30 I can trace back to late 2012 seeing a foot doc because my feet hurt but was told this was a bony deformity. I attributed it to being on my feet so much as a nurse. I never put together this was progressing small fiber neuropathy and docs certainly would never have a clue till they totally disabled me. 0:25:00 In the spring of 2013, my left foot swelled and was painful. I had done nothing. I could never be athletic because of my childhood disease but did the treadmill daily prior for decades. I saw another foot doc, told him just what I’m telling you and he ordered an MRI. He told me the MRI showed I bruised myself so I had injured myself. I adamantly said I did not, he became angry, threw the report at me to inform me I was wrong. Well I now know they are all Incompetent. So it was June 2013 and I spent that summer in bed and the swelling subsided. 0:26:15 Fall of 2013 I returned to work and immediately my right foot swelled and became painful. I no longer could rest and figured the other got better, I would muddle through. So In October, as I walked down the hallway, I felt a snap and thought this might be a breakthrough but quickly realized things got worse. I didn’t know what to do but happened to run into an orthopeadic doc from my days in the hospital, showed him my foot and said I don’t even know what specialist I should see because I’ve seen them all. He recommended his associate, a foot and ankle surgeon. I made an appointment not knowing I was a lamb being led to slaughter. 0:29:00 November 2014, I was seen and work up done by his fellow who is already a podiatrist, now doing a fellowship in foot and ankle surgery. By now the pain In my feet was unmistakably burning of my soles. I told him everything but had no clue my demise started with Cipro, but even If I had, it would never had been recognized. He did say that my symptoms sounded like neuropathy and asked If I was diabetic which I was not. Subject dropped, never recorded on my medical records I recently discovered. Follow up MRI showed severely ruptured peroneal tendon and things were too bad for rehab. Surgery was my only option. I needed a fix. I had to work so I signed for surgery December 20, 2013 so I could finish my obligations before Christmas break to minimize my sick time. Mind you I could barely walk but I was always Superwoman and this was just how I functioned even as sick as I was. 0:31:00 I had been recruited to accompany the high school choir as a pianist because of political downsizing and building politics leaving the High School Music teacher without other options. He was the president of our union and powerful. But he paid a price just like me In his lifetime. I didn’t know him well and was actually afraid of him but he was desperate, he heard I was quite the pianist , listened to me play, and said “yep, you're good enough”. Now his standards of good enough, I found out as a did this for several years, was pretty high. He was one of the most talented musicians that I’ve ever been privileged to work with. I was again on fire as I worked with him and his Choir.     Nerve block   0:34:00 He protected me when people in management were abusing me and forcing me to go against my nursing license and this was a gift. On December 20, 2013, I went into surgery not knowing the life ending decision that I was embarking on. I was given a Popliteal Nerve Block for pain control post op and receiving general anesthesia. I left, felling no pain, got my narcotics and went home very ok. 0:36:10 The following day the nerve block wore off and I began screaming at the top of my lungs. Nurses in pain, like anyone, do not think rationally, because in retrospect, I had been nursing for 20 years in a hospital and the only patients I’ve ever heard scream like that were in a burn unit in the 80’s when pain control was barbaric. I’ve also endured a natural birth of a 10.5 pound baby and I didn’t scream like that. By evening, I broke down and called the surgeon who assured me I was almost over the hump. Ha. 0:38:25 My best friend and husband stood there paralyzed in fear as I demanded the bottle of narcotics fearing I would take them all. I screamed give me 3 fucking Vicodin. I knew that wouldn’t kill me but even in those days you knew that prescription was not going to last. I also screamed that my husband had to remove the bandages because they were giving more pain. He faints at the sight of blood but I was a crazy woman. 0:39:15 Finally, the surgeon after insisting I might have a blood clot first and I said absolutely not. There’s no redness swelling, tenderness. Then he said have you ever had back problems. I say no then remembering I pulled my back out the previous June but it healed. So he orders an MRI of my Lumbar spine. The MRI is done and my back is a mess Im told (every part of my spine is gone and so Is my jaw). 0:40:30 Flouroquinolone destroys every part of the body on a cellular level - CC has degeneration of her spine - she endures 3 epidurals in an effort to determine the source of the pain 0:43:30 CC under goes 3 epidural invasive, harmful, toxic spinal injections - she has been out of work for months and in tremendous pain - epidural is a steroid that is injected into the spine to decrease swelling, but if you read the data, it does not work, it is a bogus money making procedure - the doctor tells CC her only-from-the-knee-down pain is from her back, her sciatica nerve 0:45:00 CC then undergoes a very painful procedure - the doctor realizes CC has bad neuropathy, and tarsal tunnel syndrome - he tells her to see a neurologist, but CC has to find one - Feb 2014 CC sees a neurologist 0:46:30 Just prior to the MRI date, I am In agony and my husband has no tolerance for my pain thinking I’m a whiner. I drive myself to an ER at 4:30 in the morning in desperation. I tell them my story, which I recently read their documentation and all I can say Is; are they on drugs, does anyone even listen to the patient anymore, total incompetence. I think they’ll do the MRI sooner and I can get answers. Wrong. Narcotics (Tramadol-now classified by DEA (Drug Enforcement Agency) as a controlled substance Class 4 opiate and Valium-a muscle relaxant). Prior it was considered a safe opiate.   Misdiagnosis   0:47:45 CC saw the neurologist: That man I’m sure is on drugs even though I knew I was. He kept leaving the exam room, I’d have to go out and find him, he does no neurological exam and states I need to see a neurosurgeon. 0:49:00 CC says hospitals cover up medical errors causing harm and death - CC tells about a nurse serial killer who was caught and put in jail - some nurses knew this was happening - The Good Nurse by Charles Graeber is a book about it - a nurse went to the DA (District Attorney) and they exhumed a body, but the hospital didn't tell the examiner what drug to look for based on meds being diverted in the hospital 0:51:10 The pathologist tested 100 drugs, but not the one the whistleblower nurse had reported - and the serial killer nurse went on - worked at 9 institutions - they think he probably killed 300 to 400 people 0:52:00 CC is not glad she is alive, she wished the drug had of killed her - but she loves her kids and is plugging along - I See the neurosurgeon who emphatically shows me the MRI pointing out there in NO compression on those nerves. That pain Is not coming from your spine. I get a second opinion somewhere else and he says the same. He says you have to see a neurologist and I said I did, he sent me to you. He sets up an appointment the following day in that office. 0:53:15 Unfortunately I saw a nurse practitioner but it really wouldn’t have mattered. I ask her sobbing do you think I have MS. She so compassionately comes over and holds my hand and emphatically states there is no way you have MS. Wrong. Nurses are taught never to do such a thing but she felt so confident In her skills that she violated a sacred nursing ethic. But I feel relieved as I sat in the waiting room surrounded by patients horrendously deformed by neurodegenerative diseases. She put me on Gabapentin and orders another EMG of my arms , follow up in three months with a bonafide neurologist. 0:55:30 I return to my surgeon, he sees the horrendous EMG which although abnormal, unfactual and just documentation to support another surgery which was unneeded. I’ve now been out of work for over 3 months, in desperation. He sees the EMG report says I have Tarsal Tunnel Syndrome and offers to operate on that and maybe later do the other foot. I need to work, I think this might be the answer so I agree. I’m so stupid. Desperate people do desperate things. 0:57:00 I refuse the popliteal block because my gut tells me that this is not good. I come through that surgery and while convalescing decide I’ve got to see that neurologist before July. I see him in April. He’s not only incompetent, he’s a liar I now know. He raises his eyebrows that I had the TTS and says I do not recommend the other foot. I told him what the surgeon said and he just doesn’t comment. Conspiracy of Silence.      "I asked him what he found and he refused to tell me."   0:59:00 He orders the vitamin levels I demanded reluctantly even though this Is research based. He says he wants to repeat the EMG on my legs. I tell him I have the appt for the arms June He says good do arms and legs. Wrong. 1:00:00 I show up at the hospital June 5th for the EMG with his partner. He looks at the order and starts ranting that he’s not going to do 4 limbs in one day and he’s got a splitting headache and has had a horrendous day. I offer to reschedule and he rants No. I now have been scouring the internet trying to find help because I’m even weaker. He then begins a two hour session of electrical shocks as he mutters only to himself as my friend holds my hand trying to help me through the pain. But, I finally hear him say ok, this is starting to make sense. I know he found something. When we are done I ask him what he found and he refuses to tell me. I beg him to see me because he’s the only Board Certified Neuromuscular Neurologist in the area. He says no. 1:01:30 I furiously start calling for the results. The neurologist doesn’t call me back. Finally I call and tell the nurse he better call me because if Im dying, I need to know to make arrangements. Takes days to even connect but I have now discovered there are Peripheral Neuropathy Centers of Excellence and the closest is several states away. I get an appt in less than 2 weeks. The local 2nd neurologist finally calls me back and tells me the EMG didn’t show much in those exact words. I say I’m so weak I can barely get out of bed and he offers me physical therapy. I refuse and politely tell him that I need answers so I’m leaving the state. He becomes angry putting up barriers to getting my records which ultimately I don’t need. Good people don’t care what others wrote. But because I’m a nurse, and know the ropes, I do obtain the EMG report which report which is 8 pages long single spaced starting with the statement this is a highly abnormal and complex EMG. Idiocy. Lies. 1:04:45 I go to the out of state famous guy and to my unknown luck, I show up on a day Obama was In town- I’m the only one there. All the extensive testing is done that day only needing a specialized MRI machine that is not available most places . Skin punch biopsy, 17 tubes of blood, 4 limb EMG done In less than 30 minutes. No begging for any test and more I would never have known. But he does say, because he was the first person that actually listened to me, find out the precise location on your body where they injected you for that block. 1:06:00 Two weeks after seeing the famous neurologist I return for the results but now I’m one of the herd of patients there. He tells me you have small fiber neuropathy probably from Cipro since that’s when it started but of course was placed on other neurotoxic drugs as every body organ began to disintegrate. I also have B6 toxicity which is neurotoxic (seen by the local neurologist several months earlier but never told). He goes on to explain that I had very sick nerves that could not sustain the further injury of a neurotoxic nerve block and they should have never given that to you. He adds and if you think I’m going to court for you I’m not. He states there Is nothing he can do for me. I sob and ask how I will support myself and his response was I could go on disability. He tells me he’s busy and no longer has time for me. I plead that I’m so weak I can barely get out of bed and he scolds me saying you’re not that weak. He ushers me out hysterical.       Another misdiagnsois   1:07:30 I return home. Still feeling like I’m dying and I really wish I had. On Saturday night, I’m desperate to see anyone who will help me. My long term internist had left the practice before the tendon rupture but I work with her husband. I email him and beg for his wife to call me and she does. I ask her the name of her Internist as I’ve seen multiple ones with no help and she tells me. 1:08:30 I see that internist shortly and am too weak to even sit upright to speak. She, upon entering, demands I sit up to speak. I cry and tell her I’m too weak. She does listen o my story and has a fuller history to more accurately understand. After my story her response is let’s do a brain MRI because they’ve MRId everything but that. I get that done and she calls me the next night telling me it looks like I have MS. I need to see that kind of Neurologist. I tell her I will not see anyone local. She sets me up with the nearest big city prestigious university head of MS. 1:10:00 That guy was not only Incompetent, he abuses human beings. He demands further invasive testing which was done there and my civil rights were violated and I was treated like an animal. 2 weeks later he tells me there is no doubt I have MS and wants me on toxic drugs immediately. I’m scared but too abused to accept this so I travel 9 hours to a nationally renowned hospital, lying in the back seat of our compact car writhing in pain. He does listen to my story. His verdict is that’s a weird story, but I have seen weird stories. But, I would not take those meds, continue to monitor your brain MRIs and if you get more damage, then take them. Good enough for me. 1:11:45 I have to return to the first MS guy and he’s angry but does not refuse to continue seeing me which many do. I have a few years of monitoring with no further damage revealed but cannot take his verbal abuse. I tell him how he’s hurting people with the things he says, he’s outraged, tries to pawn it off on me and I stand my ground and say I had someone beside me who heard everything you said. I point out the repeated things he said to me, he starts to grovel and says he never intended to hurt me. I respond, I know you didn’t so that’s the point of this conversation. You're clueless about your verbal abuse. I never go back because of that and other things. 1:13:00 In 2016 I read a medical journal article that is titled 40 red flags this is not MS. The first red flag is small fibre neuropathy. I email the lead author from a Colorado. He emails me back within 5 minutes. I tell him why I think I’ve been misdiagnosed. He says go see his coauthor whose closer. I do. The verdict there was I do not meet the complex criteria that Is universally accepted to diagnose MS. The McDonald Criteria. But I should be monitored. A recent medical publication cites 1:5 are misdiagnosed as MS some being on toxic drugs for decades. There is no real test for MS. So why didn’t the head of MS at a city prestigious university not understand the McDonald criteria? Because his big ego and status made he think he knew best. Scary.     Black Box Warnings   1:14:00 CC says recent research shows 1 in 5 MS patients have been misdiagnosed, and they may have been on toxic medication for decades 1:16:00 Black Box warnings on medication come from reports of harm from patients, it is not doctors submitting reports of adverse reactions - there is 1 doctor who is an adverse drug reaction researcher and he is a good man - he is the reason many of the Black Box warnings are at the FDA - CC contacted him and told about her symptoms 1:17:30 Small Fibre Neuropathy (SFN) - basically damage to the nerve - there is also Large Fibre Neuropathy, diabetics get - in MS patients, they experience neuropathy because the damage in their brain manifests the pain, not the peripheral nerve 1:18:45 The pain after her surgery was so bad CC would not have survived without an opioid - she had been prescribed Tramadol, but it was not labeled as an opioid, but it is an opioid and more dangerous than others 1:20:00 1.5 years later I’m (was) still on Tramadol for self preservation and having been told by a Johns Hopkins peripheral nerve neurosurgeon that after 9 months that nerve was not going to heal. My only options were meds or a spinal stimulator implantation. Now I’m near total psychosis. I’m obsessed with death In that I cant stop reading about It. I get pleasure from this. I sob 24/7. I can’t leave the house because I’m a public spectacle. I never ever took more than was directed. One day I take it, start to sob more and realize this poison is making me worse. I abruptly stop them. I go into withdrawal and writhe in pain everywhere for weeks. But when it’s over, my horrendous anesthetic nerve injury pain is gone. My brain was recreating the pain to get the Opioids. Tramadol was labeled in August 2014 by the DEA a a controlled substance, so providers didn’t think it was addicting even though it was an Opioid. Now we know about the corruption between the FDA and Big Pharma and the Opioid Crisis is the tip of the iceberg. My psyche Improved but I will never be normal. 1:22:30 The last years have been spent looking for The Holy Grail, trying alternative medicine and therapies but I now know my life is over. I will never work again, my personality is different as is my perception of people. One by one you r abandoned by friends, coworkers, family, religious entities and finally God. I live in unbelievable pain 24/7 that cannot be relieved unless I risk further brain injury. I’m too weak to leave the house and spend much time in bed. Very little left. I see that my situation Is the result of global profit driven societies from the rich down to the poor. 1:23:30 CC goes for stem cell therapy in Mexico as did others poisoned by flouroquinolones - and CC did respond well, but every body else got worse - CC's quality of life improved enough she could connect with others globally for mutual support - they all have multi system damage - CC was treated better by Mexican health care workers than any American. --------------------------------------------------------------------------------- Be a podcast patron Support Medical Error Interviews on Patreon by becoming a Patron for $2 / month.  Or $5 / month to be a Premium Patron and watch the video versions of Medical Error Interviews. Be my Guest If you are a survivor, a victim’s surviving family member, a health care worker, advocate, or policy maker and have a medical error experience you would like to share, send me an email with a brief description of your experience:  RemediesPodcast@gmail.com  Scott Simpson:  Counsellor + Podcast Host + Patient Advocate I am a counsellor, patient advocate, and - before I became sick and disabled - a passionate triathlete. Work hard, train hard, rest hard. Like me, many of my clients at Remedies Counseling have experienced the often devastating effects of medical error. I have been living with HIV since 1998, and thanks to research and medications, it is not a problem in my life.  I have been living with ME (myalgic encephalomyelitis) since 2012, and thanks in part to medical error, it is a big problem in my life. Need a Counsellor? If you need a counsellor for your experience with medical error, or living with a chronic illness(es), I offer online video counseling appointments. **For my health and life balance, I limit my number of counseling clients.**  Email me to find out if I have any counseling appointments open:  RemediesOnlineCounseling@gmail.com Remedies Counseling - Making Life Better Have you had traumatic experiences with the health care system? Are you living / struggling with a chronic illness?  Do you need a counsellor with proven expertise and experience to make life better? Book an appointment with Scott online at RemediesCounseling.com RemediesOnlineCounseling@gmail.com

Charles Graeber discusses his book, "The Breakthrough: Immunotherapy and the Race to Cure Cancer," at the University of Louisville Kentucky Author Forum on Nov. 15, 2018. Interviewed by Thomas Gajewski, MD, PhD. Charles Graeber, New York Times bestselling author of The Good Nurse, details the astonishing scientific discovery of the code to unleashing the human immune system to fight — and possibly even cure — cancer. For decades, scientists have puzzled over one of medicine’s most confounding mysteries: Why doesn’t our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses-tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer’s “penicillin moment,” a revolutionary discovery in our understanding of cancer and how to beat it.

Nearly 2 million Americans annually are diagnosed with cancer. With immunotherapy, there's new hope in the race to cure cancer. Learn more in my interview with NY Times best-selling author Charles Graeber.

Charles Graeber’s critically acclaimed The Breakthrough: Immunotherapy and the Race to Cure Cancer, chronicles the path to what the 2018 Nobel Prize committee recognised as our “penicillin moment” against cancer when they awarded the Medicine prize to James P. Allison and Tasuku. Variously reviewed as “fascinating and artful” (New York Times) and “deft, detailed, fascinating”(Nature) Graeber’s medical thriller,interlaces personal stories of patients and researchers as he tracks the journey to the cure and demystifies the science. Supported by The University of Auckland Faculty of Medical and Health Sciences.

On today's show we welcome Dr. Daniel Chen MD PhD, formerly Vice President, Global Head of Cancer Immunotherapy at Genentech/Roche and now Chief Medical Officer at IGM Biosciences to continue our current exploration of immunotherapy in the fight against cancer. In April we spoke to Charles Graeber, author of The Breakthrough, and today we are very lucky to welcome Dr. Chen, one of the leading pioneers of immunotherapy from Charles' book. In the show he furthers our understanding of the state of cancer immunotherapy and its recent advancements. Dr. Chen expertly balances the excitement and passion around the amazing leaps that have been made with a keen sense of purpose and caution around over playing the hand medicine has currently been dealt. We chat about Dr. Chen's own experience in the field over the last 20 years and what it has meant in the last decade to bring the latest drugs to market. Our guest unpacks a host of the technical terms and concepts, so that even the most uninitiated can grasp the basics of immunotherapy for cancer. We go on to talk about which forms of cancer are seeing the best results in response to immunotherapy and why, what the next few years may look like and the important role that big data, machine learning and AI can play in the progress we so badly need. For all this and more be sure to tune into our show today!

On today’s show we welcome Dr. Daniel Chen MD PhD, formerly Vice President, Global Head of Cancer Immunotherapy at Genentech/Roche and now Chief Medical Officer at IGM Biosciences to continue our current exploration of immunotherapy in the fight against cancer. In April we spoke to Charles Graeber, author of The Breakthrough, and today we are very lucky to welcome Dr. Chen, one of the leading pioneers of immunotherapy from Charles’ book. In the show he furthers our understanding of the state of cancer immunotherapy and its recent advancements. Dr. Chen expertly balances the excitement and passion around the amazing leaps that have been made with a keen sense of purpose and caution around over playing the hand medicine has currently been dealt. We chat about Dr. Chen’s own experience in the field over the last 20 years and what it has meant in the last decade to bring the latest drugs to market. Our guest unpacks a host of the technical terms and concepts, so that even the most uninitiated can grasp the basics of immunotherapy for cancer. We go on to talk about which forms of cancer are seeing the best results in response to immunotherapy and why, what the next few years may look like and the important role that big data, machine learning and AI can play in the progress we so badly need. For all this and more be sure to tune into our show today!

In Episode 2, Mere gives her rundown of a book about the most prolific serial killer in US history, The Good Nurse written by Charles Graeber. Jess raises suspense for the up coming Queen Mary trip and tells mere about the ghosts they may encounter. Enjoy and don't get in a pickle! **(WARNING:This story contains details of murder that some listeners may find disturbing.)

On this episode of The Open Mind, we're delighted to welcome Charles Graeber, an award winning science journalist and contributor to myriad publications including the New Yorker, National Geographic, MIT Technology Reviewand Wiredfor which he is a contributing editor. His new book, “The Breakthrough: Immunotherapy and the Race to Cure Cancer” probes the treatment that aspires to make cancer chronic instead of fatal and ultimately to beat it forever. Dr. James Gulley, director of medical oncology, chief of immunology at the National Cancer Institute and National Institutes of Health calls “The Breakthrough” a must read. “It not only provides good background and good understanding for patients, but it's also a wonderful read, easily picked up but not easily put down. I'd recommend it for any patient interested in immunotherapy of cancer.”  In Graeber's own words, “Immunotherapy is the only approach to cancer that could actually curate it: a mutating answer to a mutating problem.” 

Today's guest is Charles Graeber (@charlesgraeber), author of the book The Breakthrough: Immunotherapy and the Race to Cure Cancer. Charles tells us about the amazing strides that have been made recently in finding a cure for cancer. The progress is so notable that Charles was comfortably able to use the word ‘cure' in the book's subtitle! That means that cancer is on the way to becoming not just treatable but actually curable for millions of people all over the world. The book and today's conversation center around the fact that up until now, researchers have been on the wrong trail when it comes to finding the answer posed by this deadly disease. Immunotherapy works by leveraging our body's own immune system to kill cancer cells, which was previously considered impossible by the scientific community. Charles unpacks some of the history of these ideas, why they have remained on the fringes for so long and why they are now being viewed in a new light. We discuss broader trends in medicine and tech and Charles goes quite in-depth explaining what we know so far and how it is and might be used going forward. For an inspiring chat on this life-changing topic, be sure to join us!

Today’s guest is Charles Graeber (@charlesgraeber), author of the book The Breakthrough: Immunotherapy and the Race to Cure Cancer. Charles tells us about the amazing strides that have been made recently in finding a cure for cancer. The progress is so notable that Charles was comfortably able to use the word ‘cure’ in the book’s subtitle! That means that cancer is on the way to becoming not just treatable but actually curable for millions of people all over the world. The book and today’s conversation center around the fact that up until now, researchers have been on the wrong trail when it comes to finding the answer posed by this deadly disease. Immunotherapy works by leveraging our body’s own immune system to kill cancer cells, which was previously considered impossible by the scientific community. Charles unpacks some of the history of these ideas, why they have remained on the fringes for so long and why they are now being viewed in a new light. We discuss broader trends in medicine and tech and Charles goes quite in-depth explaining what we know so far and how it is and might be used going forward. For an inspiring chat on this life-changing topic, be sure to join us!

We continue our conversation with New Times Bestselling author Charles Graeber. In this episode we talk about 'Whistleblowers,' Charles's new book 'The Breakthrough, Immunotherapy and The Race To cure Cancer," and The Disappearance Of Madelaine McCaine on Netflix. We also chat about the writing process and how nurses can become writers. Charles Graeber is a contributing editor for Wired and a contributor to publications such as The New York Times, The New Yorker, GQ, Vogue, and many others. He has received many awards and his work has been featured on NPR, CNN, the BBC, and numerous other media outlets. Check out his latest book 'The Breakthrough' available on Amazon, and The Disappearance Of Madelaine McCain On Netflix. Special thanks to our sponsor Nursebackpack Download the Nursebackpack app today at https://nbp.app.link/nursesandhypochondriacs Throw us some bucks, and help support our cause! Venmo: @Nurses-Hypo https://www.gofundme.com/nurses-hypochondriacs-podcast Give us a rating on iTunes. Need consulting or have questions: nursesandhypochondriacs@gmail.com

When nurse Charlie Cullen was arrested in 2003, journalists were quick to dub him "The Angel of Death." But Cullen was neither a mercy killer nor a simple monster. He was a son, a husband, a father, a best friend, and a valued caregiver. He was also implicated in the deaths of as many as 400 people, and may be the most prolific serial killer in American history.Cullen's career in the world's most trusted profession spanned sixteen years, across nine hospitals. In this episode we talk to New York Times Best selling author Charles Graeber about why he chose to write The Good Nurse, his 6 year long research into the case, and how he got to talk to Charles Cullen. We also discus similar "Angel Of Death" true crime scenarios, how 'The Good Nurse,' may affect medical malpractice cases, and much more! Charles Graeber is a contributing editor for Wired and a contributor to publications such as The New York Times, The New Yorker, GQ, Vogue, and many others. He has received many awards, and his work has been featured on NPR, CNN, the BBC, and numerous other media outlets. Checkout his latest book 'The Breakthrough' available on Amazon, and The Disappearance Of Madeleine McCain On Netflix. Nurses get 1 CE for listening fill out survey at https://www.surveymonkey.com/r/NY9DZC9 Special thanks to our sponsor Nursebackpack Download the Nursebackpack app today at https://nbp.app.link/nursesandhypochondriacs Throw us some bucks, and help support our cause! Venmo: @Nurses-Hypo or https://www.gofundme.com/nurses-hypochondriacs-podcast Give us a rating on itunes. Need consulting or have questions: nursesandhypochondriacs@gmail.com

In this podcast, we were joined by Mr Charles Graeber, award-winning journalist and author who recently published The Breakthrough: Immunotherapy and the Race to Cure Cancer along with Dr James Gulley, Head of the Immunotherapy Section and Director of the Medical Oncology Service at the Center for Cancer Research within the National Cancer Institute. Together Mr Graeber and Dr Gulley delved into the significance of this moment in science, what the progress has been and explore what is next on the horizon within immuno-oncology. Both Dr Gulley and Mr Graeber will be presenting at the 5th annual IO360°, February 6-8 at The Crowne Plaza Times Square Hotel, NYC. For more information visit IO360°.

The Murders of Aaron Pajich and Matthew Digby...Vile goblins Jemma Lilley and her house mate Trudi Lenon had a selfish and stupid plan to make history as serial killers. Their first and only victim was Aaron Pajich, a trusting 18 year old computer game enthusiast with Asperger's syndrome, who was friends with Trudi's son.After Lauren Batcheldor's house was burgled in 2010, she and Richard Walsh decided to take the law into their own hands. It would set off a chain of events that led to the kidnapping and torture death of Matthew Digby in Wollongong.Become a Bloody Murder Patron (for as little as $1 per month, which you can cancel at anytime) and have access to dozens of Patron only episodes (including our whole first season!) with new patron only content added every month!Go to https://www.patreon.com/bloodymurderLevels $5 and over go into our monthly merchandise draws and get FREE stickers and hand-made Barney Badges!See our website! bloodymurderpodcast.com for all our social media links, contact details, a gallery, fabulous merchandise (check out our new Bloody Murder SHOES! and now STICKERS and BACKPACKS and DUFFEL BAGS!!) and much much more.Wanna buy us a drink? Here's a donate link.Thanks to Ary from Murder Under the Midnight Sun for supplying this weeks True Crime Nerd Time. It's a review of Charles Graeber's The Good Nurse.True Crime Nerd Time is a new segment on Bloody Murder and it needs your help because it stars you! We want you, our listeners, to submit your recommendations for anything true cime related! It could be books, TV shows, movies, documentaries, exhibitions, graphic novels, art, music etc. So send us your brief story (we’ll read it out) or record your story (it can just be a recording on your phone, and we’ll play it!). We will also publish it on our website. Keep it to about 2 mins please or 200 words. Email here! bloodymurderpodcast@gmail.com. Oh and if you give us your postal address we'll send you some stickers as a reward! See acast.com/privacy for privacy and opt-out information.

After his December 2003 arrest, registered nurse Charlie Cullen was quickly dubbed “The Angel of Death” by the media. But Cullen was no mercy killer, nor was he a simple monster. He was a favorite son, husband, beloved father, best friend, and celebrated caregiver. Implicated in the deaths of as many as 300 patients, he was also perhaps the most prolific serial killer in American history. Cullen’s murderous career in the world’s most trusted profession spanned sixteen years and nine hospitals across New Jersey and Pennsylvania. Charles Graeber has written for Wired, GQ, The New Yorker, New York, Outside, Bloomberg Businessweek, and the New York Times, among others. His work has received numerous awards including the 2011 Ed Cunningham Award for outstanding international journalism from the Overseas Press Club and a New York Press Club prize. Born in Iowa, he lives in Nantucket, MA, and Brooklyn, NY.

Over the course of the last year we've spoken to many different people from all walks of life. We asked them one simple question: "If there was one thing you could change about the criminal justice system, what would it be." This final episode of Season 2 is a compilation of their answers. We're joined by criminal defense attorney Christopher Zervic, as well as the guys and gals from The Generation Why Podcast and the Thinking Sideways Podcast. The cast of guests includes: Jason Lucky Morrow from HistoricalCrimeDetective.com, Julie Strickland, Charles Graeber author of the book The Good Nurse, true-crime author Dianne Fanning, clinical psychologist James M. Cantor, Dr. Michelle Elliott, Thought Catalog author M.J. Pack, documentary filmmaker Jan-Willem Breure, and Noreen Gosch from The Johnny Gosch Foundation.

When asked to imagine the perfect place to perform serial murder most imagine something dark and creepy, but the truth of the matter is that the perfect place to kill is actually the same place in which most of us are born and die: a hospital. This is a place where death is not only common, but expected. Many of the victims are already incapacited and there's a steady stream of them coming in each day. Not to mention the fact that the tools for killing are readily available in the form of various dangerous drugs. Combine that with a hospital's reluctance to report any activity which may cost them a lawsuit and it's no wonder that Charles Cullen was able to get away with killing more than 40 patients over the course of 16 years at nine different institutions. In this episode we speak with Charles Graeber, author of The Good Nurse, and recount the terrifying story of a serial killer nurse and the broken system around him which facilitated and possibly covered up his killing spree.

On today's Satellite Sisters, Liz, Sheila, Monica and Lian tackle: Sheila's take on the latest fashion trends and what she wears on her head when she is home alone. No photos please.  Lian's has a warning on trendy new food and diet advice.  Her German Shepherd Mika disapproved this new advice years ago. Liz's advice on Sheryl Sandberg's advice  in the New York Times about women speaking up in a meeting. And Monica's wants some movie-going suggestions this holiday weekendso all the sisters weigh in.   Plus Liz is putting Operation Sea Turtle Phase Two in effect .  It has three prongs, of course.  Hear all about them.  She is also starting Errol Morris' new bestseller about the trails of Jeffrey MacDonald entitled A Wilderness of Error. The podcast serial turned her on to true crime. And Monica also finished another true crime book which she calls a real page turner:  The Good Nurse by Charles Graeber.   

After his December 2003 arrest, registered nurse Charlie Cullen was quickly dubbed "The Angel of Death" by the media. But Cullen was no mercy killer, nor was he a simple monster. He was a favorite son, husband, beloved father, best friend, and celebrated caregiver. Implicated in the deaths of as many as 300 patients, he was also perhaps the most prolific serial killer in American history.Cullen's murderous career in the world's most trusted profession spanned sixteen years and nine hospitals across New Jersey and Pennsylvania. When, in March of 2006, Charles Cullen was marched from his final sentencing in an Allentown, Pennsylvania, courthouse into a waiting police van, it seemed certain that the chilling secrets of his life, career, and capture would disappear with him. Now, in a riveting piece of investigative journalism nearly ten years in the making, journalist Charles Graeber presents the whole story for the first time. Based on hundreds of pages of previously unseen police records, interviews, wire-tap recordings and videotapes, as well as exclusive jailhouse conversations with Cullen himself and the confidential informant who helped bring him down, THE GOOD NURSE weaves an urgent, terrifying tale of murder, friendship, and betrayal. Were it not for the hardboiled, unrelenting work of two former Newark homicide detectives racing to put together the pieces of Cullen's professional past, and a fellow nurse willing to put everything at risk, including her job and the safety of her children, there's no telling how many more lives could have been lost. THE GOOD NURSE-A True Story of Medicine, Madness and Murder-Charles Graeber     

Fellow podcaster Mel Evans drops by MBSing for some October-appropriate scary killer talk! She is as delightful as she is knowledgeable about women who have committed murders. From Lizzie Borden to Snapped, we cover a lot of killer ground and have a total blast along the way. I don't think I ever would have pondered the different ways/reasonings females commit such crimes or the disparity between how they're treated for such sprees versus the drive behind male-committed killings and the way most are shrugged off as chemical imbalances. It's a weird thing we do as a society to slap a "crazy" label on any woman acting out of sorts. More of that talk and plenty of lighter fare in this truly wonderful ep.   Notes: An Hour With Your Ex Mel's Bro Jackson guide to lady serial killers Michelle McNamara's True Crime Diary That Mexican murder episode of Snapped Mr. Nanny ep of How Did This Get Made? The Good Nurse author Charles Graeber on How Was Your Week?

HWYW Book Club! HWYW Book Club! Welcome back to HWYW Book Club. CHARLES GRAEBER is this week's guest. He wrote the fabulous True Crime book THE GOOD NURSE, and he's here to tell Julie about the banality of evil, and how bureaucratic failure is scarier than a lone psychopath, how sex stuff can make murderers confess, why his book was originally called THE PRESSURE SUIT, and how, to the man who killed around 400 people, the story could be best described as a "dark comedy." Plus: Finally appreciating PIPPIN, and how it's about choosing disappointment over death; a nosy dog named Ringo; Bridget Everett as Iggy Pop; and the return of Spoony's BORED-walk Empirezzzzz recaps!

Here's a second chat I had with Charles Graeber a few months after we originally spoke about his true crime book, The Good Nurse: The True Story of Medicine, Madness, and Murder. This conversation hits a few different points from the first time around, and now the book is available in paperback.