Podcasts about cipro

Secondo il rapporto Svimez 2024, l’Italia registra nuovamente un divario di crescita rispetto all’Eurozona: il Pil nazionale è cresciuto solo dello 0,7%, contro una media UE del +1%. A sorprendere è il Mezzogiorno, che ha registrato una crescita dell’1%, superiore a quella del Centro-Nord (+0,6%) e della media italiana. In particolare, si distinguono Sicilia (+1,5%) e Campania (+1,3%). Il Centro rimane comunque la macro-area trainante a livello cumulato: dal 2022 al 2024 ha registrato una crescita del 9,8%, contro l’8,6% del Sud e il 5,6% del Centro-Nord. Il Mezzogiorno ha beneficiato in modo rilevante degli investimenti pubblici e del Pnrr, che hanno inciso per 0,6 punti percentuali sulla crescita dell’area, contro 0,4 punti nel resto del Paese. Il motore della crescita nel Sud è stato il settore delle costruzioni (+3%) e i servizi (+0,7%), mentre l’industria ha mostrato una certa tenuta (+0,1%) rispetto alla leggera flessione nel Centro-Nord (-0,2%). L’agricoltura invece ha performato peggio (+0,5% contro +2,9%). Gli investimenti pubblici hanno toccato i 45 miliardi, metà dei quali mobilitati dai Comuni. Tra le regioni in calo figurano Molise (-0,9%), Calabria (-0,2%), Liguria (-0,5%) e Veneto (-0,4%). Il commento è di Luca Bianchi, direttore Svimez.Assolombarda, Alvise Biffi eletto Presidente: “Ripensare l’impresa”L’Assemblea Privata di Assolombarda ha eletto Alvise Biffi come nuovo Presidente per il quadriennio 2025-2029, insieme ai Vicepresidenti che comporranno il Consiglio di Presidenza. Nel suo primo intervento ufficiale, Biffi ha delineato una visione chiara per il futuro dell’impresa: aumentare la produttività ripensando i modelli industriali. Al centro della sua strategia l’integrazione dell’intelligenza artificiale, ancora scarsamente adottata in Italia secondo Istat, solo l’8% delle aziende la utilizzava nel 2023 e l’urgenza di colmare il divario con le regioni tedesche più avanzate in termini di ricerca e sviluppo. Innovare, per Biffi, significa anche affrontare il cambiamento nel mercato del lavoro: il 40% degli annunci nella zona Assolombarda riguarda profili ad alta qualificazione impattati dall’IA, ma permane un forte mismatch tra domanda e offerta. Quasi la metà delle imprese ha difficoltà a trovare figure chiave come esperti digitali, energy manager o progettisti green. Altro tema cardine: l’energia. Con costi europei molto più alti rispetto a USA e Cina, Biffi propone di sganciare il prezzo dell’elettricità da quello del gas naturale e spingere sulle rinnovabili fino a coprire il 50% del mix elettrico. Nel medio periodo, secondo il presidente, servirà puntare anche sul nucleare di nuova generazione e sui gas verdi, come il biometano e l’idrogeno, per decarbonizzare i settori industriali più energivori. Interviene proprio Alvise Biffi, presidente di Assolombarda.Volare con il mondo in guerra: le rotte off limits, i rischi e le nuove tratte per evitare i missiliL’escalation del conflitto tra Israele e Iran ha ridisegnato le rotte del traffico aereo internazionale. Le compagnie evitano sempre più frequentemente gli spazi aerei considerati ad alto rischio per via di possibili attacchi missilistici, ma in assenza di un’autorità globale che imponga regole comuni, le decisioni sono frammentate: ogni Stato stabilisce se e quanto tenere aperto il proprio cielo, spesso per ragioni economiche. Ne derivano paradossi operativi, come il sorvolo dell’Afghanistan classificato a rischio inferiore rispetto all’Iran pur essendo area instabile. Le alternative attuali si dividono in due direttrici: a nord, passando dal Mar Caspio e Afghanistan; a sud, attraversando Egitto, Mar Rosso e Arabia Saudita. Ma anche rotte un tempo neutre, come Cipro o il sud della Turchia, sono ora oggetto di attenta valutazione. La mancanza di informazioni ufficiali condivise costringe le compagnie a valutazioni autonome, facendo affidamento sulle raccomandazioni di Paesi come USA, Regno Unito o Germania. Le conseguenze economiche sono pesanti: rotte più lunghe comportano più ore di volo, più carburante e maggiori costi operativi, in un contesto in cui il prezzo del petrolio è in crescita (Brent +8% in pochi giorni). Tutto ciò si traduce in una pressione ulteriore sui margini delle compagnie, proprio mentre il settore stava cercando di riprendersi. Il commento è di Andrea Giuricin, docente di Economia dei Trasporti, Università Bicocca di Milano.

Una centrale operativa di truffatori online che promettono guadagni strabilianti con un piccolo investimento iniziale di 250 euro, con il solo obiettivo di svuotare i conti delle vittime. È a Cipro e l'ha scoperta il giornalista Andrea Sceresini, ospite di oggi.

In This Episode You'll Learnhttps://www.drhughwegwerth.com/post/fluoroquinolone-poisoning-mold-urine-tests-show-90-toxin-drop-in-12-weeksThe Problem: How fluoroquinolone antibiotics (like Cipro) can “wake up” mold inside the body and make symptoms worse.Why Mold Lingers: Mold spores can stay in your gut or lungs for 10–30 years without you knowing.Testing Made Easy:Urine tests find mold better than blood tests because the toxins collect in pee.Three tests (Aug 2024, Nov 2024, May 2025) showed the mold levels drop.Key Results:Ochratoxin fell from 25 to 6.1.Aflatoxin went from high to zero.Mycophenolic acid vanished completely.Gentle Wins: Starting slow keeps fragile bodies safe while clearing mold.Take-Home Hope: Even if doctors said “It's all in your head,” you can heal with the right plan.Why You Should ListenClear Steps: Easy words, clear plan—perfect if medical talk confuses you.True Story: Real test dates, real numbers, real recovery.Next Move: Hear how you can book a Zoom call with Dr. Hugh for help anywhere in the world.Press play and discover that where there is help, there is hope!

Běhání se psem může být zdravý koníček nebo vrcholový sport. Šimon Cipro z projektu Běhejsepsem.cz nám prozradil spoustu informací a k tomu přidal motivaci, abychom se nebáli začít kdykoliv a s jakýmkoliv psem.Jak začít s canicrossem?Jak trénovat?Jaké podoby může běh se psem mít?

La protagonista di questo episodio di "Pillole di Eurovision" è Nina Zizic, in gara per Cipro all'Eurovision Song Contest 2025 con il brano "Dobrodosli"".Iscriviti alla nostra lega del Fantaeurovision "Pillole di Basilea" a questo link: https://fantaeurovision.com/league?id=68128769afcb6b66615cc4f5Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/pillole-di--4800610/support.

La protagonista di questo episodio di "Pillole di Eurovision" è Emmy, in gara per Cipro all'Eurovision Song Contest 2025 con il brano "Laika party".Iscriviti alla nostra lega del Fantaeurovision "Pillole di Basilea" a questo link: https://fantaeurovision.com/league?id=68128769afcb6b66615cc4f5Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/pillole-di--4800610/support.

Il protagonista di questo episodio di "Pillole di Eurovision" è Theo Evan, in gara per Cipro all'Eurovision Song Contest 2025 con il brano "Shhh".Iscriviti alla nostra lega del Fantaeurovision "Pillole di Basilea" a questo link: https://fantaeurovision.com/league?id=68128769afcb6b66615cc4f5Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/pillole-di--4800610/support.

What's the problem with antibiotics anyway? On this episode of Vitality Radio, Jared passionately answers this question. There is no antibiotic that doesn't cause harm. That's not to say they don't have their place, but as Jared explains, they are almost never necessary and almost always prescribed for common problems like UTI's and sinus infections. You'll learn why many infections don't need, and won't respond to antibiotics, the ramifications of even a single dose of antibiotics, and how antibiotic superbugs are a real problem. Jared delves into why antibiotics are overused, side effects of particularly dangerous forms, and the effects on mental health and the immune system. This show will be followed with one on antibiotic alternatives and ways to rebuild your microbiome after antibiotic exposure.Additional Information:#264: Emotional Vitality: Jen's Story Part 1 - From Addiction and Mental Illness to Vitality#266: Prescribing Poisons Part 2. Ibuprofen, PPI's, and Flouroquinalone AntibioticsVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

In questa puntata:- Focus: un'isola divisa. A Cipro con Luigi Gemmi 

La storia delle Civiltà del Mediterraneo, da Greci e Fenici ad altri popoli, racconta di una regione che ha influenzato cultura, scambi e progresso.

Have you seen neuropathy and chronic myalgia that patients believe happened after taking Cipro?  I've seen it several times.  This might be one of those cases. Best sleep he's had in 20 years after the first treatment of what looked like Sural Nerve Entrapment. I'm covering the Sural Nerve Entrapment in Sydney at the end of March.   https://chinesemedicineeducation.com/product/motor-point-acupuncture-trigger-point-needling-nerve-entrapments/   Online Courses on Podia: https://richardhazel.podia.com For the month of March (my birthday month) I'm giving discounts. 20% off any courses and bundles with the code MARCH20 50% off the Motor Point Location Video Course with the code BIRTHDAY50  

Mít v rodině psa a děti zároveň je radost, ale i výzva. Karolína Cipro, zkušená pejskařka a zakladatelka projektu Běhej se psem, v podcastu Po mateřských stopách sdílí, jak skloubit výchovu dětí a psů a proč je důležité nepodceňovat výběr plemene.

Fino al 16 marzo, alla Galleria Virgilio Guidi di San Donato Milanese, sarà possibile visitare la mostra “Schermi d'Arte- Il paravento da oggetto a favola”, ideata e progettata da Gabriella Brembati, direttrice di Spazio Arte Scoglio di Quarto, con la curatela del critico e storico dell'arte Alberto Barranco di Valdivieso. Tra le opere in mostra anche il "Mappavento" dell'artista Rebecca Forster. Nata in Gran Bretagna, ha viaggiato e vissuto a Cipro per poi approdare in Italia. A City Life racconta la sua arte e i suoi nuovi progetti.

Via i progetti irrealizzabili entro la scadenza. Ridimensionamento degli obiettivi impossibili, spostamento degli investimenti a rilento verso altre fonti di finanziamento. Alla scadenza formale del Recovery Plan manca ormai meno di 18 mesi. Con l'arrivo di Raffaele Fitto alla Commissione europea e la delega alla sua attuazione, per l'Italia il problema politico di presentarsi alla scadenza senza rimediare una figuraccia si fa sempre più impellente. Il successore di Fitto al ministero degli Affari europei - Tommaso Foti - per raggiungere l'obiettivo di spendere le risorse chieste entro i tempi stabiliti ha davanti a sé una sfida quasi impossibile: accelerare la spesa ad un ritmo esponenziale, oltre cinque miliardi al mese. L'Italia - il maggior beneficiario in assoluto con la Spagna del primo esperimento di debito europeo - ha chiesto fin qui ben quattro revisioni. Germania, Grecia, Finlandia, Irlanda e Cipro ne hanno presentate tre, altri dieci Paesi due. Foti ha annunciato a questo giornale mercoledì scorso che in marzo presenterà in Parlamento la quinta richiesta di modifica: quasi certamente l'ultima, poi occorrerà sperare nell'inevitabile proroga che Foti nega solo per ragioni di opportunità. Non è nulla di nuovo: se il Pnrr si fermasse qui, la media dei fondi già utilizzati - un terzo del totale - sarebbe la stessa della programmazione ordinaria dei fondi europei. Con un occhio al successo spagnolo, a Palazzo Chigi sanno cosa non ha funzionato del piano italiano: Madrid ha concentrato gli investimenti su meno obiettivi e concentrati verso il sistema produttivo. Il nostro Pnrr - nonostante i tentativi ripetuti di modifica - ha più di 260mila appalti. Una polverizzazione che avvantaggia i piccoli interventi sul territorio e i Comuni, meno le imprese. Basti qui citare il caso del progetto Transizione 4.0, sei miliardi a disposizione per l'installazione di pannelli fotovoltaici sui tetti dei capannoni. Secondo le stime che circolano nel settore, fin qui non sarebbero stati accolti progetti per nemmeno un miliardo: colpa delle procedure complicatissime per ottenere i fondi. E così fra Palazzo Chigi e i ministeri si lavora a tessere l'ennesima tela di Penelope. Il commento è di Luca Dal Poggetto, Analista di Openpolis esperto di Pnrr.Unicredit compra ancora e supera il 5% in GeneraliNel mezzo del doppio assalto a Commerzbank e a Banco Bpm e a pochi giorni dall uscita allo scoperto su Generali, Unicredit batte le stime del mercato con i risultati del 2024. Nel frattempo il timone resta puntato sulle partite in m&a in corso, a partire da Banco Bpm per cui il ceo Andrea Orcel non esclude un rilancio. E su Generali il banchiere alza il velo: Unicredit ha superato il 5%. Secondo quanto risulta potrebbe essere cresciuta sia la componente in azioni proprie della banca, arrivata nelle scorse settimane al 4,2%, sia il pacchetto di titoli gestito per conto di clienti. La nuova quota sarà annunciata a giorni in base alle tempistiche previste per l acquisto di partecipazioni rilevanti. La banca guidata da Andrea Orcel chiude l esercizio con un utile netto contabile di 9,7 miliardi, in rialzo del 2%, e un utile netto escluse le dta a 9,3 miliardi (+8%). Nel solo quarto trimestre il risultato contabile è stato di 1,97 miliardi e l utile netto di 1,6 miliardi (oltre i 1,44 miliardi il consensus), in calo rispetto agli 1,9 miliardi dello stesso periodo del 2023. Nel settembre scorso Unicredit ha aperto il consolidamento italiano ed europeo acquisendo il 9% di Commerzbank, di cui poi è salita fino al 28% con derivati. In novembre l istituto ha poi lanciato un ops da 10,1 miliardi su Banco Bpm a un concambio di 0,175 azioni Unicredit per ogni titolo Banco Bpm. La terza mossa è stata annunciata negli ultimi giorni con l acquisto del 4,1% in Generali. La quota potrebbe essere messa in palio nelle prossime settimane in vista dell assemblea che l 8 maggio sarà chiamata a rinnovare il cda della compagnia. Ne parliamo con Alberto Grassani. Sole 24 ore.Il mondo ha perso la bussola - Terzo rapporto sul mondo postglobaleOggi alle 17.30 nella sede di Confindustria Como, in collaborazione con Intesa Sanpaolo è stato presentato il terzo Rapporto sul mondo postglobale intitolato "Il mondo ha perso la bussola", a cura del Centro di Ricerca e Documentazione Luigi Einaudi.Quali sono, se ancora ci sono, i punti cardinali per orientarsi nel caos del mondo postglobale? Il terzo Rapporto del Centro Einaudi prova a esplorare i possibili scenari in un mondo sempre più complesso e imprevedibile. E offre un analisi delle grandi trasformazioni globali, con particolare attenzione alle elezioni del 2024 in 64 Paesi, che hanno coinvolto quasi metà della popolazione adulta mondiale e il 60% del PIL globale. Discute inoltre della necessità di riconnettere i mercati finanziari all economia reale e del concetto di antifragilità, ovvero la capacità di adattarsi nell incertezza. Interviene al microfono di Sebastiano Barisoni Mario Deaglio, docente emerito Economia Internazionale Università di Torino.

In Italia si legge poco. Pochissimo. Il 65 per cento della popolazione sopra i 16 anni non ha aperto un libro nell'ultimo anno, secondo i dati Eurostat analizzati da Lorenzo Ruffino. La media europea? Il 47 per cento. Significa che mentre altrove il libro rimane un'abitudine, da noi è un'eccezione. Peggio di noi, in Europa, solo Romania, Turchia, Cipro e Serbia. Leggere poco non è un peccato veniale. È una condanna. A cosa? Alla mediocrità politica, al dibattito pubblico ridotto a risse televisive in cui il tono della voce sostituisce la sostanza, alla classe dirigente che non sa articolare un pensiero complesso ma sa imitare il verso del cane davanti alle telecamere. A una parlamentare che va in televisione facendo il verso del cane. Non stupisce, allora, che il titolo di studio sia il principale discrimine: il 66 per cento delle persone laureate in Italia legge almeno un libro all'anno, contro il 40 per cento dei diplomati e il 19 per cento di chi ha solo la terza media. Numeri drammatici, se confrontati con la media europea: 77 per cento per i laureati, 50 per cento per i diplomati e 32 per cento per chi ha la licenza media. Chi legge, pensa. Chi pensa, riconosce la propaganda, smaschera le bugie, esercita il dubbio. Non è un caso che in un Paese che legge poco si tenda a credere a tutto. O a chi urla di più. In Svizzera il 19 per cento della popolazione non legge libri. In Francia il 28 per cento. In Spagna il 46 per cento. In Italia il 65 per cento. Qui non è una questione di svago o di preferenze: è un dato politico. È un problema di libertà. E la libertà ha a che fare anche con la conoscenza. #LaSveglia per La NotiziaDiventa un supporter di questo podcast: https://www.spreaker.com/podcast/la-sveglia-di-giulio-cavalli--3269492/support.

Cambiamento climatico, sfruttamento indiscriminato delle risorse naturali, inquinamento e collasso degli ecosistemi. Un viaggio tra le isole e le coste del Mediterraneo - da Linosa a Cipro, da Tunisi alle Kerkennah, da Mazara a Samos - per raccontare come sta cambiando il nostro mare. Conversazione con il giornalista Stefano Liberti, autore di "Tropico Mediterraneo" (Editori Laterza). Foto di Francesco Bellina.

L'Italia è il paese con più siti Unesco al mondo, definiti come patrimonio dell’umanità. Sono 60. Abbiamo un immenso patrimonio culturale, oltre che turistico e paesaggistico, eppure siamo ben lontani dall’investire e dal valorizzarlo al meglio. Secondo l’ultimo rapporto di Federculture, l’Italia è agli ultimi posti nella classifica europea per spesa complessiva nella cultura in rapporto al Pil: siamo allo 0,5%. Peggio di noi fa solo la Grecia con lo 0,3%, e siamo alla pari con Cipro, contro lo 0,9% della media europea, lo 0,8% della Germania, l’1,2% della Francia, l’1% della Spagna. Eppure si tratta di un settore che conta 825mila occupati. L'intera filiera del sistema produttivo culturale e creativo vale in Italia 104,3 miliardi di euro di valore aggiunto. Ne discutiamo grazie a un libro pubblicato da Egea dal titolo “La cultura è di tutti”, scritto da Paola Dubini, nostra ospite e docente di Management all’Università Bocconi di Milano, insieme a Christian Greco, direttore del Museo Egizio di Torino.

Kulturni center Pekarna v Mariboru deluje že 30 let. Nekdanja vojašnica, specializirana za peko kruha, je zdaj zanesljivo pribežališče alternativne kulture in misli. V pekarni avtonomne mariborske kulture se mesi kakovosten program, ekipa za zdaj uspešno odvrača tudi politične in kapitalske pritiske. Obiskali smo različna prizorišča, se pogovarjali s prvoborci in aktivnimi uporabniki. Tudi o ozadjih imen kluba Gustaf in bukvarne Ciproš, pa o grafitu, ki je aktualnega župana privabil v Pekarno z dvema sprejema.

What Are Mitochondria and How Fluoroquinolones Affect ThemCheck out my 65 blogs on this topicIn today's episode, Dr. Hugh will talk about mitochondria and how they play an important role in your health. This episode is especially helpful if you've been affected by antibiotics like fluoroquinolones, which can damage mitochondria.Here's what you'll learn:What are mitochondria?Mitochondria are the energy makers of your cells. They help produce power so your cells can work properly.Each cell in your body can have between 15 and 2000 mitochondria, depending on the cell type.How do fluoroquinolone antibiotics work?Medications like Cipro and Levofloxacin target the DNA of bacteria, stopping it from copying itself. This is how the bacteria are killed.However, these antibiotics can also damage your mitochondria because your mitochondria have DNA that is similar to bacterial DNA.Why are mitochondria at risk?Unlike the nucleus of your cell, which is well-protected, mitochondria have ring-shaped DNA that is exposed.This makes it easy for antibiotics to damage mitochondria, leading to long-term health problems.What happens when mitochondria are damaged?Damaged mitochondria can cause nerve pain (neuropathy) and make you feel tired.Mitochondria also help cells decide when to live or die, so when they're harmed, it can cause your cells to stop working properly.Dr. Hugh explains how fluoroquinolone antibiotics can affect your body by targeting the mitochondria. If you're struggling with side effects from these drugs, this episode will help you understand why and how to begin your path to recovery.

L'ultima capitale divisa d'Europa è quella di Cipro, Nicosia: e al momento unificarla sembra quasi impossibile. Con Anna Casaglia, professoressa di Geografia economico politica all'Università di Trento e autrice di “Nicosia Beyond Partition”  Questo e gli altri podcast gratuiti del Post sono possibili grazie a chi si abbona al Post e ne sostiene il lavoro. Se vuoi fare la tua parte, abbonati al Post. I consigli di Anna Casaglia “Città divise. Belfast, Beirut, Gerusalemme, Mostar e Nicosia” di di Jon Calame ed Esther Charlesworth Il film “Torna a casa, Jimi!” “Altai” di Wu Ming Cipro sul Post La riunificazione di Cipro è impossibile? L'indipendenza di Cipro Learn more about your ad choices. Visit megaphone.fm/adchoices

Francesca Sensini"Afrodite viaggia leggera"Sulle rotte dell'amorePonte alle Graziewww.ponteallegrazie.itAfrodite è la dea dell'amore, della bellezza. Lo era nell'antichità e lo è oggi. Da Milo a Parigi, da Cipro a Citera, dalla Mesopotamia ai confini del mondo, prende quello che è suo, senza chiedere il permesso, fin dalla notte dei tempi. Perché lei è il primo amore dell'umanità. Figlia dei signori della luce, è una reazione chimica, il risultato di una mescolanza, una statua di marmo senza braccia, lo sguardo rivolto a ciò che manca. Eppure rappresenta la pienezza: è signora della forza e della gioia, padrona del piacere e del sorriso. Valica limiti e confini, quelli della legge e quelli dell'ordine, quelli della storia e quelli della geografia.Frutto dell'incontro tra lo sperma del cielo e la spuma del mare, nasce ovunque, a ogni approdo, là dove qualcuno sente pungere al fianco l'assillo della vita. Anche lei non ne è immune. Si innamora di Adone e lo contende a Ade, si nasconde tra gli arbusti di mirto, i versi di Saffo, i dardi di Atalanta, in attesa che qualcuno sia degno di lei. Afrodite, marina e dorata, celeste e terrena, viaggia leggera sulle rotte del Mediterraneo. E nei suoi viaggi incontra la guerra, il potere. Scende in battaglia sotto le mura di Troia, si imbarca con gli Argonauti, insieme a Giasone e Medea, e dall'acropoli di Corinto difende l'amore da ogni violenza. Perché solo quello che non conosce costrizioni né ragioni– incantesimo naturale, scambio, trionfo di grazia – germoglia, fiorisce. E vince ogni cosa.Francesca Sensini è nata a Genova nel 1974. Dopo una laurea in Lettere classiche ,è partita per la Francia, dove ha insegnato in varie università e ha continuato i suoi studi, dottorandosi in Italianistica all'Università Paris-Sorbonne. Ha vissuto a Parigi per dieci anni, per altri tre sul lago del Bourget, tra i monti della Savoia, e ora è tornata a vedere il mare, a Nizza, dove è professoressa associata di Italianistica all'Università Côte d'Azur. Comparatista di formazione, tra i suoi amori più grandi vi è quello per il Mediterraneo antico, e per la Grecia in particolare, con i suoi miti. Per Ponte alle Grazie ha pubblicato La trama di Elena (2023).IL POSTO DELLE PAROLEascoltare fa pensarewww.ilpostodelleparole.itDiventa un supporter di questo podcast: https://www.spreaker.com/podcast/il-posto-delle-parole--1487855/support.

Offerta di ESCLUSIVA NORDVPN: Vai su https://nordvpn.com/dentrolastoria per acquistare 2 anni + 4 mesi extra di NordVPN con uno sconto esclusivo + fino a 20 GB gratis su Saily - l'app eSIM per viaggiatori! Il nostro canale Youtube: https://www.youtube.com/channel/UC1vziHBEp0gc9gAhR740fCw Sostieni DENTRO LA STORIA su Patreon: https://www.patreon.com/dentrolastoria Abbonati al canale: https://www.youtube.com/channel/UC1vziHBEp0gc9gAhR740fCw/join Il nostro store in Amazon: https://www.amazon.it/shop/dentrolastoria Sostienici su PayPal: https://paypal.me/infinitybeat Dentro La Storia lo trovi anche qui: https://linktr.ee/dentrolastoria Il 1974 è stato un anno di stravolgimenti, di speranze (a volte disilluse), di fatti delittuosi. Il ritrovamento dell'Esercito di Terracotta in Cina, il Cubo di Rubik, la Rivoluzione dei Garofani, le bombe a Brescia e sull'Italicus, l'affermazione delle Brigate Rosse, il referendum sul divorzio, il crollo della dittatura dei colonnelli, la separazione di Cipro, la bancarotta di Michele Sindona, le dimissioni di Nixon... l'elenco di eventi cardine è sterminato. Che ricordo avete del 1974? Cosa vi ha lasciato quell'anno, come ha cambiato la vita vostra e dei vostri cari? L'editoriale odierno è un invito alla riflessione a cinquant'anni di distanza. Learn more about your ad choices. Visit megaphone.fm/adchoices

Il nostro documentario girato a Cipro: https://www.youtube.com/watch?v=bhzJ6fGVlng&ab_channel=NovaLectio INSTANT GEOPOLITICA, il mio nuovissimo libro sulla Geopolitica: https://amzn.to/40RLZsi Canale YouTube Nova Lectio: https://www.youtube.com/c/NovaLectio Voce Simone Guida Testo e ricerca di Mauro Indelicato: https://www.instagram.com/mauroindelicato?igsh=MXkxcndnNzcyZmYzOA%3D%3D https://t.me/mindelicato (canale telegram di Mauro Indelicato per le news dal mondo) Learn more about your ad choices. Visit megaphone.fm/adchoices

Their chemistry puts them in a chemotherapy drug class, and their adverse effects reflect it. Despite this, they are marketed as antibiotics and carelessly prescribed.Support the Show.

Il nostro documentario girato a Cipro: https://www.youtube.com/watch?v=bhzJ6fGVlng&ab_channel=NovaLectio INSTANT GEOPOLITICA, il mio nuovissimo libro sulla Geopolitica: https://amzn.to/40RLZsi Canale YouTube Nova Lectio: https://www.youtube.com/c/NovaLectio Voce Simone Guida Testo e ricerca di Mauro Indelicato: https://www.instagram.com/mauroindelicato?igsh=MXkxcndnNzcyZmYzOA%3D%3D https://t.me/mindelicato (canale telegram di Mauro Indelicato per le news dal mondo) Learn more about your ad choices. Visit megaphone.fm/adchoices

Join hosts Brooke and Elena as they discuss the little known (but extremely dangerous) side effects of ‘Cipro’, the drug very commonly prescribed to SCI patients for urinary tract infections. They expose Cipro’s black box FDA warning, and outline examples of how it could contribute to weight gain, mental health issues, skin/tissue degradation, negative cardiovascular […] Continue Reading The post WAGS of SCI: The Podcast – Ep. 147 – Ciprofloxacin: The Dangers You Probably Didn't Know About This Antibiotic first appeared on WAGS of SCI.

Gaza: bombardate quattro scuole piene di sfollati in quattro giorni. Arabia Saudita: 20 anni ad un insegnate per post sui social media. Corea del Sud: il sindacato Samsung dichiara sciopero a tempo indeterminato. Giappone: sempre più donne di mezza età e anziane prendono lezioni di danza classica.Questo e molto altro nel notiziario di Radio Bullets a cura di Barbara Schiavulli

JOIN OUR VIP TRIBE FOR ONLY $1 --> DianeKazer.com/VIP GET YOUR FREE DETOX --> DianeKazer.com/FREEDETOX BECOME A PATIENT --> DianeKazer.com/CALL BINDERS --> DianeKazer.com/BINDERS In today's Cleanse Heal Ignite episode with Dr Diane Kazer for Warrior Wednesdays we're bringing you an information-packed episode from beautiful Mexico, with insider info that I promise you're not going to get anywhere else. I'm back with my special guest, Dr Jack Kunkel, to discuss the TOP 5 ARSONISTS THAT ARE MAKING YOU SICK. And, how to free yourself from these blocking factors and finally step into your God-given beauty, energy and vitality. Dr. Jack and I are talking ABC - ALWAYS BE CLEANSING. If you're not taking some kind of binder every day you're screwed. So what's a binder? Well, it's the 4th stool of the ‘Using Food as Medicine' first, followed by supplements to expedite, deepen and improve your healing journey and get rid of the Arsonists…permanently. And just who are these Arsonists? They are a multitude of toxins that create fires of inflammation in the body and must be effectively excreted by the body. We are living in the most toxic time in human history, so if you want to see REAL results, you must be on at least one binder daily. And it's important to learn about the different binder types, what they bind to and and how they excrete differently. That's why in Module 5 of The Warrior Cleanse, I score these binders on their effectiveness. For example, you. may have heard that Activated Charcoal is the gold standard, or all you need to detox, and simply put, it's not. This is why I highly recommend you work with me and my team to run the best labs to get to the bottom of WHY you're still suffering with symptoms and sickness. Are you finally ready to truly transform and transcend your health roadblocks that no other doctors have been able to pin down? The time is now to book a call. Removing the ‘arsonists' that have been setting fire to your body as long as you've had them in...without doing a detox after to clean up the mess they made is like driving your car in it's wrecked state after an accident. These arsonists - breast implants, silver fillings, IUD's, mesh material, Botox, fillers and more are leaving a trail of toxins that damage your tissues, and need some serious TLC after you remove them. So tune in and get the insider scoop that the mainstream and conventional systems do not want you to know. Why? Because the system is designed to keep you sick and disempowered. And, that's exactly what we are shifting here at CHI Holistic Health Ministry. We're helping our patients to free themselves and reclaim their divine health, beauty, energy and vitality. Are you ready to finally free yourself? WE WILL COVER -->The Complete Rockefeller Playbook keeping everyone in sickness and disi-ease: Western Medicine Poisons, beauty toxins, mammograms, radiation, gadolinium, medical devices, and so much more -->The truth about Cholesterol: what it is and healthy levels -->The common side effects you may be experiencing due to Medications for Blood Pressure, Cholesterol and Acid Reflux. -->Lyme is a BIOWEAPON and its prevalence is skyrocketing -->Why is Herpes on the Rise? And how is it really caused? -->The #1 Prescribed Drug, CIPRO, and why you MUST avoid it! -->MOLD! The nearly invisible, pervasive toxin that's wreaking havoc on our body -->Why everyone's immune system is overly taxed and screaming for help…and how to resolve this. -->Broken Belief Systems: mental constructions, unresolved emotions and stress (Mal)adaptations -->Get ready! Dr Jack Kunkle is joining our VIP Group again! Are you a VIP Tribe member? If so, you'll have access to ask him all your questions! And if you're not a VIP member yet…what's stopping you? Join us today for just $1 DianeKazer.com/VIP I love to hear from you! Drop your comments and questions in the live chat and I will address them during the show.

NOTAS DE ELENAMaterial complementario de la escuela Sabática para adultosNarrado por: Patty CuyanDesde: California, USAUna cortesía de DR'Ministries y Canaan Seventh-Day Adventist ChurchLUNES, 01 DE JULIOUNA SEGUNDA OPORTUNIDADBernabé estaba dispuesto a ir con Pablo, pero deseaba llevar consigo a Marcos, quien había decidido de nuevo consagrarse al ministerio. Pablo se opuso a esto. "No le parecía bien llevar consigo" a uno que durante su primer viaje misionero los había abandonado en tiempo de necesidad. No estaba inclinado a excusar la debilidad manifestada por Marcos al abandonar la obra en procura de la seguridad y las comodidades del hogar. Recalcaba que uno con tan poca fibra era inapto para un trabajo que requería paciencia, abnegación, valor, devoción, fe y disposición a sacrificar, si fuera necesario, hasta la vida misma. Tan áspera fue la disputa, que Pablo y Bernabé se separaron, siguiendo el último sus convicciones y llevando consigo a Marcos. "Bernabé tomando a Marcos, navegó a Cipro. Y Pablo escogiendo a Silas, partió encomendado de los hermanos a la gracia del Señor" (Los hechos de los apóstoles, pp. 164, 165). Desde los primeros años de su profesión de fe, la experiencia cristiana de Marcos se había profundizado. A medida que estudiaba más atentamente la vida y muerte de Cristo, obtenía más claros conceptos de la misión del Salvador, sus afanes y conflictos. Leyendo en las cicatrices de las manos y los pies de Cristo las señales de su servicio por la humanidad, y el extremo a que llega la abnegación para salvar a los extraviados y perdidos, Marcos se constituyó en un seguidor voluntario del Maestro en la senda del sacrificio. Ahora, compartiendo la suerte de Pablo, el preso, comprendía mejor que nunca antes que es una infinita ganancia alcanzar a Cristo, e infinita pérdida ganar el mundo y perder el alma por cuya redención la sangre de Cristo fue derramada. Frente a la severa prueba y adversidad, Marcos continuó firmemente, como sabio y amado ayudador del apóstol (Los hechos de los apóstoles, p. 363). Cuando Dios prepara el camino para la realización de cierta obra, y da seguridad de éxito, el instrumento escogido debe hacer cuanto está en su poder para obtener el resultado prometido. Se le dará éxito en proporción al entusiasmo y la perseverancia con que haga la obra. Dios puede realizar milagros para su pueblo tan solo si este desempeña su parte con energía incansable. Llama a su obra hombres de devoción y de valor moral, que sientan un amor ardiente por las almas y un celo inquebrantable. Los tales no hallarán ninguna tarea demasiado ardua, ninguna perspectiva demasiado desesperada; y seguirán trabajando indómitos hasta que la derrota aparente se trueque en gloriosa victoria. Ni siquiera las murallas de las cárceles ni la hoguera del mártir los desviarán de su propósito de trabajar juntamente con Dios para la edificación de su reino (Profetas y reyes, p. 196). 

Oggi parliamo dell'accordo raggiungo al G7 su 50 miliardi di aiuti all'Ucraina, dei migranti bloccati tra Cipro Sud e Cipro Nord e dell'età della pensione per chi oggi ha 30 anni. ... Qui il link per iscriversi al canale Whatsapp di Notizie a colazione: https://whatsapp.com/channel/0029Va7X7C4DjiOmdBGtOL3z Per iscriverti al canale Telegram: https://t.me/notizieacolazione ... Qui gli altri podcast di Class Editori: https://milanofinanza.it/podcast Musica https://www.bensound.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Send us a Text Message.PLEASE SHARE! This is the tell all story of how fluoroquinolone antibiotics led to disabling and potentially permanent side effects for my previously healthy 32 year old husband. Since taking Cipro in March of 2021, Joey has suffered from non-stop chronic pain,  weakness, and joint and muscle injuries that do not heal. This particular class of antibiotics is dangerously overprescribed despite coming with an FDA black box warning that they should only be used as a last resort. Doctors do not take it seriously, but you should! This information might literally save your life. If you listened to this week's episode on the history of antibiotics, than you've already heard this! I wanted to put this information in a shorter, more digestible chunk that's easy to share. Support the show! Buy Me a CoffeeVenmo @Shea-LaFountaine

Learn all about the history of public administration with Victoria and guest Thomas Cipro, Binghamton History student!

Notiziario Mondo di Radio Bullets, a cura di Ambra Visentin 

Oggi è arrivato sul tavolo del Consiglio europeo il rapporto realizzato da Enrico Letta sul mercato unico nell'Ue: l'ex premier si è soffermato sul "disastro industriale" costituito dal sistema delle telecomunicazioni in Europa e sulla "vergogna" rappresentata dall'acquisto dall'estero del 78% delle armi. Dopo la presentazione del rapporto è iniziato il vertice durante il quale si è parlato i mercato dei capitali e debito comune. Dopo oltre tre ore di stallo, sulla parte relativa all''Unione del mercato dei capitali si cerca uno sblocco con una proposta franco-tedesca per convincere Irlanda, Lussemburgo, Cipro e Malta. La nuova ipotesi di mediazione punta a mettere d'accordo i 27 con l'idea di "migliorare la convergenza ed efficienza" della "supervisione" dei mercati dei capitali, invitando "la Commissione a lavorare alle condizioni per mettere in condizione le autorità europee" di esercitare effettivamente una supervisione dei capitali sistemici più rilevanti e gli attori dei mercati finanziari. Lo si apprende da fonti diplomatiche. Continua anche lo scontro sull'ipotesi di fare nuovo debito comune dopo il 2026 ma il cancelliere austriaco Karl Nehammer ha respinto l'idea. "La linea austriaca è molto chiara. Ma non solo in Austria, bensì in altri Stati cosiddetti frugali: condividere il debito significa sempre condividere insieme il peso degli interessi. Abbiamo dovuto farlo una volta a causa della pandemia. Stiamo ancora pagando alti interessi sul debito. Questo a sua volta limita la capacità di agire", ha detto al suo arrivo al vertice Ue. "Dobbiamo pensare diversamente. Dobbiamo rafforzare il mercato dei capitali nell'Unione europea: abbiamo bisogno di un accordo adesso", ha sottolineato. Intanto il professor Deaglio in un editoriale oggi su La Stampa spiega perché secondo lui "vanno ascoltate le dure verità di Draghi".Ne parliamo con Adriana Cerretelli, editorialista Sole 24 Ore Bruxelles, e Mario Deaglio, docente Economia Internazionale Università di Torino.Focus economia Vinitaly 2024, interviste ai produttori La 56esima edizione del Vinitaly si è svolta dal 14 al 17 aprile 2024 a Veronafiere. Presenti più di 4mila cantine, in rappresentanza di tutto il made in Italy enologico e da oltre 30 nazioni.In Italia la vendemmia del 2023 è stata la più leggera dal Dopoguerra: la produzione si è fermata a 38,3 milioni di ettolitri, con un calo del 23,2% sui volumi 2022. Nei mercati mondiali il vino ha frenato e ha perso 802 milioni nel 2023, mentre il nostro Paese ha registrato una flessione dell'1% dell'export. I consumi sono calati dell'8% dal 2019, in particolare i rossi. Ma il Prosecco ha trascinato la crescita degli spumanti. Per capire come sta andando il settore del vino e le prospettive per l'anno in corso, Sebastiano Barisoni e Andrea Ferro, durante Focus economia, hanno intervistato diversi produttori ed esperti.La liquidità del petrolio per l'intelligenza artificialeIeri Biagio Simonetta ha scritto che sia l'Arabia Saudita sia gli Emirati Arabi Uniti stanno lavorando per diventare una superpotenza nel mondo dell'intelligenza artificiale investendo la liquidità ottenuta dal petrolio. Questi Paesi stanno costruendo costosi data center nel deserto per supportare la GenAI (l'intelligenza artificiale generativa, che è in grado di generare testo, immagini, video, musica o altri media in risposta a delle richieste, dette prompt). I data center nel deserto arabo stanno crescendo a ritmo sostenuto, ma vanno incontro a difficoltà non secondarie: le temperature torride e il pericolo che minuscole particelle di sabbia possano introdursi nelle strutture. Al momento, i Paesi del Golfo sono indietro. Anche rispetto all'Europa. Secondo la società di ricerca DC Byte, alla fine del 2023 gli Emirati Arabi Uniti avevano 235 megawatt di capacità di data center e l'Arabia Saudita 123 megawatt. Il vantaggio emiratino è dovuto al fatto che il Paese ha iniziato a costruire data center molto prima, circa 20 anni fa all'interno del programma Dubai Internet City. Ciononostante, i data center nella regione sono pochi, rispetto ai 1.060 megawatt della sola Germania. Per colmare il divario, sauditi ed emiratini stanno lavorando, mettendo mano ai ricchi portafogli. I Paesi del Golfo puntano anche sul fronte dei chip, risultando - secondo il Financial Times - fra i clienti più assidui di Nvidia per i processori H100. Ma la fase programmatica va al di là dei data center. A luglio scorso, il primo ministro e principe ereditario dell'Arabia Saudita, Mohammed bin Salman, ha approvato la creazione del Centro internazionale per la ricerca e l'etica dell'intelligenza artificiale a Riad. Un primo passo verso un futuro che proprio bin Salman sembra aver progettato nel dettaglio, nel piano strategico Vision 2030. E adesso, secondo un rapporto di PwC, l'intelligenza artificiale contribuirà con 135 miliardi di dollari all'economia saudita nel 2030, rendendo il Regno il più grande beneficiario di tecnologia in Medio Oriente. Secondo il New York Times, il governo dell'Arabia Saudita prevede di creare un fondo di 40 miliardi interamente dedicato allo sviluppo dell'intelligenza artificiale. Ne parliamo con Biagio Simonetta, giornalista del Sole24Ore.

Cipro sospende le domande dei richiedenti asilo siriani, la Germania invia all'Ucraina un nuovo sistema di difesa aerea Patriot e i nuovi riservisti dell'esercito israeliano

La nave della Ong spagnola ha lasciato Cipro e dovrebbe raggiungere la Striscia di Gaza entro due o tre giorni. Trasporta 200 tonnellate di aiuti umanitari destinati al popolo palestinese sull'orlo della carestia. Ne parliamo con Veronica Alfonsi (nella foto), presidente di Open Arms Italia.

Il corridoio marittimo per inviare aiuti da Cipro a Gaza, l'annuncio di Macron del progetto di legge sull'eutanasia e l'esito delle elezioni in Portogallo

1- Striscia di Gaza. Si muove la società civile. Salpata da Cipro la prima nave con 200 tonnellate di aiuti umanitari. Appartiene all'ong catalana Open Arms impegnata in questi anni a salvare i migranti nel Mediterraneo. Lo speciale di Esteri 2- Stati Uniti. Joe Biden lancia la sua campagna elettorale con un budget da 7.300 miliardi di dollari. Scontato il no dei repubblicani. Ma con la proposta di aumentare le tasse ai ricchi per finanziare i programmi sociali il presidente uscente spera di recuperare il consenso della sinistra democratica 3- Cina. Dopo una settimana di lavori si è conclusa la doppia sessione del parlamento. L'esito più significativo una nuova legge sul governo che di fatto lo subordina ulteriormente al controllo del partito. 4- Rubrica sportiva. La storia di Mohamad Barakat la stella del calcio palestinese ucciso in un raid israeliano a Khan Yunis

Blackened American History Part 6 - Red Pill too Big to SwallowWebsite: http://www.battle4freedom.comNetwork: https://www.mojo50.comStreaming: https://www.rumble.com/Battle4Freedomhttps://www.dailymail.co.uk/news/article-13112901/Cell-networks-nationwide-Verizon-Mobile-att-down.htmlCell networks down nationwide: 911 services across America crash as AT&T, Verizon and T-Mobile customers from New York to LA report no service or connection with many phones displaying SOS messagesCustomer reports about the outage spiked around 4am Eastern time on Thursday https://www.gofundme.com/f/j7ddu-support-the-barkersSupport the Barker'shttps://www.dailymail.co.uk/sciencetech/article-13110529/electric-vehicles-prevent-illnesses-children-report.htmlSwitching to electric vehicles by 2050 would prevent 2.8 MILLION child asthma attacks and over 500 infant deaths, report claimsSwitching to electric vehicles by 2050 could save more than 500 infants' lives 37 percent of children in the U.S. live in counties with failing air pollution levelshttps://www.dailymail.co.uk/health/article-13109335/nobel-prize-winning-doctor-cure-cancer-types.htmlDoctor on the cusp of a cancer cure: Nobel Prize-winning oncologist whose discovery means killer disease could be treated with a vaccine in years to comeDr Catherine Wu has paved the way for the development of cancer vaccinesShe 'drew a picture of [myself] making a cure for cancer' in second gradehttps://www.dailymail.co.uk/health/article-13109517/Monumental-breakthrough-thousands-alopecia-sufferers-watchdogs-approve-drug-REVERSES-hair-loss.html'Monumental' breakthrough for thousands of alopecia sufferers as watchdogs approve drug that REVERSES hair lossIt has been described as a 'monumental day' for sufferers of alopecia areataThousands with hair loss are set to benefit from a breakthrough treatmenthttps://www.dailymail.co.uk/wellness-us/nutrition/article-13109931/ozempic-foods-dietitian-abbey-sharp.htmlI took the 'max strength' dose of Ozempic and lost 35lbs - from hair loss to diarrhea and 'next-level' exhaustion, here's what happenedDietitian Abbey Sharp's manager Ginger is losing a pound a week on OzempicAbbey critiqued what Ginger ate in a day, which came to only 1,100 calorieshttps://www.dailymail.co.uk/health/article-13111327/young-mother-unable-walk-antibiotic-pills-uti.htmlMother is left unable to walk after taking just three ANTIBIOTIC pills to treat a UTI: Disabled vet husband she previously cared for is also in a wheelchairTalia Smith, 44, was hospitalized after taking the antibiotic CiproflocaxinThe FDA puts a warning on Cipro, but Smith says she was not told about the risks Three years later she says she is still unable to walk and is in excruciating pain https://tuckercarlson.com/the-vladimir-putin-interview/The Vladimir Putin Interview

Jim Collins is one of the leading biomedical engineers in the world. He's been elected to all 3 National Academies (Engineering, Science, and Medicine) and is one of the founders of the field of synthetic biology. In this conversation, we reviewed the seminal discoveries that he and his colleagues are making at the Antibiotics-AI Project at MIT.Recorded 5 February 2024, transcript below with audio links and external links to recent publicationsEric Topol (00:05):Hello, it's Eric Topol with Ground Truths, and I have got an extraordinary guest with me today, Jim Collins, who's the Termeer Professor of Medical Engineering at MIT. He also holds appointments at the Wyss Institute and the Broad Institute. He is a biomedical engineer who's been making exceptional contributions and has been on a tear lately, especially in the work of discovery of very promising, exciting developments in antibiotics. So welcome, Jim.Jim Collins (00:42):Eric, thanks for having me on the podcast.Eric Topol (00:44):Well, this was a shock when I saw your paper in Nature in December about a new structure class of antibiotics, the one from 1962 to 2000. It took 38 years, and then there was another one that took 24 years yours, the structural antibiotics. Before I get to that though, I want to go back just a few years to the work you did published in Cell with halicin, and can you tell us about this? Because when I started to realize what you've been doing, what you've been chipping away here, this was a drug you found, halicin, as I can try to understand, it works against tuberculosis, c. difficile, enterobacter that are resistant, acinetobacter that are resistant. I mean, this is, and this is of course in mice models. Can you tell us how did you make that discovery before we get into I guess what's called the Audacious Project?Jim Collins (01:48):Yeah, sure. It's actually a fun story, so it is origins go broadly to institute wide event at MIT, so MIT in 2018 launched a major campus-wide effort focused on artificial intelligence. The institute, which had played a major role in the first wave of AI in the 1950s, 1960s, and a major wave in the second wave in the 1980s found itself kind of at the wheel in this third wave involving big data and deep learning and looked to correct that and to correct it the institute had a symposium and I had the opportunity to sit next to Regina Barzilay, one of our faculty here at MIT who specializes in AI and particularly AI applied to biomedicine and we really hit it off and realized we had interest in applying AI to drug discovery. My lab had focused on antibiotics to then close to 15 years, but primarily we're using machine learning and network biology to understand the mechanism of action of antibiotics and how resistance arise with the goal of boosting what we already had, with Regina we saw there was an opportunity to see if we could use deep learning to get after discovery.(02:55):And notably, as you kind of alluded in your introduction, there's really been a discovery void and the golden age of discovery antibiotics was in the forties, fifties and sixties before I was born and before you had the genomic revolution, the biotech revolution, AI revolution. Anyways, we got together with our two groups, and it was an unfunded project and we kind of cobbled together very small training set of 2,500 compounds that included 1,700 FDA approved drugs and 800 natural compounds. In 2018, 2019, when you started this, if you asked any AI expert should you initiate that study, they would say absolutely not, there's going to be two big data. The idea of these models are very data hungry. You need a million pictures of a dog, a million pictures of a cat to train a model to differentiate between the cat and the dog, but we ignored the naysayers and said, okay, let's see what we can do.(03:41):And we apply these to E. coli, so a model pathogen that's used in labs but is also underlies urinary tract infections. So it's a look to see which of the molecules inhibited growth of the bacteria as evidence for antibacterial activity and we could have measured and we quantified each of their effects, but because we had so few compounds, we just discretized instead, if you inhibited at least 80% of the growth you were antibacterial, and if you didn't achieve that, you weren't antibacterial zero in ones. We then took the structure of each molecule and trained a deep learning model, specifically a graphical neural net that could look at those structures, bond by bond, substructure by substructure associated with whatever features you look to train with. In our case, making for good antibiotic, not for good antibiotic. We then took the train model and applied it to a drug repurposing hub as part of the Broad Institute that consists of 6,100 molecules in various stages of development as a new drug.(04:40):And we asked the model to identify molecules that can make for a good antibiotic but didn't look like existing antibiotics. So part of the discovery void has been linked to this rediscovery issue we have where we just keep discovering quinolones like Cipro or beta-lactams like penicillin. Well, anyways, from those criteria as well as a small tox model, only one molecule came out of that, and that was this molecule we called halicin, which was named after HAL, the killing AI computer system from 2001 Space Odyssey. In this case, we don't want it to kill humans, we want it to kill bacteria and as you alluded, it turned out to be a remarkably potent novel antibiotic that killed off multi-drug resistant extensively drugs, a pan-resistant bacteria went after to infections. It was affected against TB, it was affected against C. diff and acinetobacter baumannii and acted to a completely new mechanism of action.(05:33):And so we were very excited to see how AI could open up possibilities and enable one to explore chemical spaces in new and different ways. We took them model, then applied it to a very large chemical library of 1.5 billion molecules, looked at a subset of about 110 million that would be impossible for any grad student, any lab really to look at that experimentally but we looked at it in a model computer system and in three days could screen those 110 million molecules and identified several new additional candidates, one which we call salicin, which is the cousin of halicin that similes broad spectrum and acts to a novel mechanism of action.Eric Topol (06:07):So before we go further with this initial burst of discovery, for those who are not used to deep neural networks, I think most now are used to the convolutional neural network for images, but what you use specifically here as you alluded to, were graph neural networks that you could actually study the binding properties. Can you just elaborate a little bit more about these GNN so that people know this is one of the tools that you used?Jim Collins (06:40):Yeah, so in this case, the underlying structure of the model can actually represent and capture a graphical structure of a molecule or it might be of a network so that the underlying structure itself of the model will also look at things like a carbon atom connects to an oxygen atom. The oxygen atom connects to a nitrogen atom and so when you think back to the chemical structures we learned in high school, maybe we learned in college, if we took chemistry class in college, it was actually a model that can capture the chemical structure representation and begin to look at sub aspects of it, associating different properties of it. In this case, again, ours was antibacterial, but it could be toxic, whether it's toxic against a human cell and the model, the train model, the graph neural model can now look at new structures that you input them and then make calculations on those bonds so a bond would be a connection between two atoms or substructures, be multiple bonds, interconnecting multiple atoms and assign it a score. Does it make, for example, in our case, for a good antibiotic.Eric Topol (07:48):Right. Now, what's also striking as you set up this collaboration that's interdisciplinary with Regina, who I know of her work through breast cancer AI and not through drug discovery and so this was, I think that new effort and this discovery led to this, I love the name of it, Audacious Project, right?Jim Collins (08:13):Right. Yeah, so a few points on the collaboration then I'll speak to Audacious Project. In addition to Regina, we also brought in Tommi Jaakkola, another AI faculty member and marvelous colleague here at MIT and really we've benefited from having outstanding young folks who were multilingual. We had very rich, deep trained grad students from ML on Regina and Tommi's side who appreciated the biology and we had very richly, deeply trained postdocs, Jon Stokes in particular from the microbiology side on my side, who could appreciate the machine learning and so they could speak across the divide. And so, as I look out in the next few decades in this exciting time of AI coming into biomedicine, I think the groups will make a difference of those that have these multilingual young trainees and two who are well set up to also inject human intelligence with machine intelligence.(09:04):Brings the Audacious Project. Now, prior to our publication of halicin, I was invited by the Audacious Project to submit a proposal, the Audacious Project is a new philanthropic effort run by TED, so the group that does the TED Talks that's run by Chris Anderson, so Chris had the idea that there was a need to bring together philanthropists around the world to go for a larger scale in a collective manner toward audacious projects. I pitched them on the idea that we could use AI to address the antibiotic resistance crisis. As you can appreciate, and many of your listeners can appreciate that we're doomed if we don't actually address this soon, in that the number of resistance strains that are in our communities, in our hospitals has been growing decade upon decade, and yet the number of new antibiotics being developed and approved has been dropping decade upon decade largely because the antibiotic market is broken, it costs just as much to develop an antibiotic as it does a cancer drug or a blood pressure drug.(09:58):But antibiotic you take once or maybe over the course of three to five days, blood pressure, drug cancer drug you might take for months if not for the rest of your life. Pricing points for antibiotics are small dollars, cancer drugs, blood pressure drugs, thousands if not hundreds of thousands. We pitched this idea that we can maybe turn to AI and use the power of AI to address this crisis and see if we could use our wits to outcompete the genes of superbugs and Chris and his team really were taken with this, and we worked with them over the course of nine months and learned how to make the presentations and pulled this together. Chris took our pitches to a number of really active and fantastic philanthropists, and they got behind us and gave us a good amount of money to launch what we have now called the Antibiotics-AI Project at MIT and in conjunction with it and also using funding from the Audacious Project, we've launched a nonprofit called Phare Bio which is French for lighthouse, so our notion is that antibiotics are public good that we need to get behind his community and Phare Bio, which is run by Akhila Kosaraju, she's the CEO and President, is the mission of which is to take the most promising molecules out of the antibiotics AI project and advance them towards the clinic through partnerships with biotech, with pharma, with other nonprofits, with nation states as needed.Eric Topol (11:18):Well, before I get to the next chain of discovery and as explain ability features, which we all like to see when you can explain stuff with AI, did halicin because of this remarkable finding, did it get into clinical trials yet?Jim Collins (11:36):It's being advanced quite nicely and aggressively by Phare Bio. So Phare Bio is in discussions with the Department of Defense and BARDA, and actually on an interesting feature of halicin is that it acts like a flash bomb in the gut, meaning that when delivered orally to the gut, it only acts briefly and very quickly in a fairly narrow spectrum manner as well, so that it can go after pathogens sparing the commensals. One of the challenges our US military face is one of the challenges many militaries face are gut issues when soldiers are first deployed to a new location, and it can disable the soldiers for three to four weeks. And so, there's a lot of excitement that halicin might be effective as a treatment to help prevent gut dysbiosis resulting from new deployments.Eric Topol (12:27):Oh wow. That's another application that I would never have thought of. Interesting, so you then moved on to this really big report in Nature, which I think this is now involving a transformer model as I recall. So you can explain the difference and you made a discovery from a massive, again, number of potential compounds to staph aureus resistant methicillin resistant agents that were very potent in vivo. So how did you make this big jump? This is a whole new structural class of antibiotics.Jim Collins (13:11):Yeah, so we made this jump, this was an effort led by Felix Wong, who's a really talented postdoc in my lab, and we got intrigued of to what extent could we expand the utility of AI and biology of medicine. As you can appreciate that, that many of our colleagues are underwhelmed by the black box nature of many AI models and by black box I mean that when you train your model, you then largely use it as a filter where you'll provide the model with some input. You look at the output and the outputs, what's of interest to you, but you don't really understand in most cases, what guided the model to make the prediction of the output that you look at and that can be very unsatisfactory for biology, interested in mechanism. It can be very unsatisfactory for physicians interested in understanding the underlying disease mechanism.(13:57):It can be unsatisfactory for biotech and drug discoveries that want to understand how drugs act and what maybe underlies meaningful structural features. So with Felix, we decided it'd be interesting if you could open up the box. So could you look inside the model to see what was being learned? We are able to open up, in this case actually, we primarily focused on graph neural nets. We now have a new piece we're just about to submit on transformers, but in this case, we could open up and look to see what were the rationales, what were the chemical substructures that the model was pointing to in each compound that was leading to the high prediction that it could make for a good antibiotic and these rationales we then used as hooks, I should notably say, that we were able to identify the rationales from these large collections using algorithms that would develop by DeepMind as part of their AlphaGo program.(14:51):So AlphaGo was developed by DeepMind as a deep learning platform to play and win go the ancient Asian board game and we used similar approaches called Monte Carlo Tree Search that allowed us to identify these rationales that we effectively then used as hooks and kind of organizing hooks on screens where you can envision or appreciate that most exposed screens give you one-offs. This molecule does what you want and silico screens are similarly designed with these rationales. We could use them as organizing hooks to say, ah, these compounds that are identified as making for very good antibiotics all have the same substructure and thus they likely in the same class and act in similar mechanism and this led us to identify five novel classes, one of which we highlighted in this piece that acts very effectively against MRSA, so methicillin-resistant staph aureus you alluded, which is probably the most famous of the antibiotic resistant pathogens that we even outside infectious are quite familiar with. It be devil's athletes, so NFL players are often hit with MRSA, whether from scraping their limbs on AstroTurf or from actually surgeries to say, for example, correct something at their knee. This new class had great efficacy in animal models, again, acting through a new mechanism.Eric Topol (16:12):Will you bring that forward like halicin through this same entity?Jim Collins (16:17):Yes. We've now provided the molecules to Phare Bio and they're digging in to see which of these might be the most exciting and interesting to advance clinically.Eric Topol (16:26):I mean, it's amazing because this area is so neglected. Maybe you can help explain, since we're talking about existential threats as we get more and more resistant antibiotics and the biopharma industry is basically not into this and it relies on the work that you've been doing perhaps or other groups, I don't know of any that are doing more than you. I mean, it's incredible to me. Is it just because of the financial aspects that there's no business in the life science industry?Jim Collins (17:03):It's an interesting challenge. So I've thought about it. I really haven't come up with a great solution yet, but I think you've got multiple factors at play. One is that I think all of us, every one of your listeners has lost someone to a bacterial infection, but in most cases you don't realize you lost them to a bacterial infection. It might be that your elderly relative went into the hospital with a condition but acquired hospital-based infection and died subsequently from that and happened quite quickly. Another cases, again, it's secondary. Notably, during the pandemic, one out of seven individuals hospitalized for Covid had a bacterial infection and 50% of those who died had a bacterial co-infection. And noted by going back to the Spanish flu of over a hundred years ago. It was as deadly as it was because we didn't have antibiotics and most of the folks that died had a bacterial co-infection.(17:56):So you have this in the backdrop, you then have that, nobody's kind of gotten behind it, so we don't have any major foundation addressing antibiotic resistance. There are no charity walks, there are no charity runs, there is no month, there is no color, there are no ribbons, there are no celebrity behind it, there's just not known so it hasn't captured the public's imagination. AThen you come with that, this backdrop of the broken market where I said shared, it's really expensive to develop a new antibiotic, but if you develop a new antibiotic, the tendency now will be to shelve it until it's desperate so now even the young companies that had developed and gotten an antibiotic through to approval often went bankrupt because the model, the market couldn't provide them with revenue to go after the next one or sustain their efforts. And so you have pharma biotech jumping out. I think we need two-pronged effort going forward. I do think we need nation states to come forward and get behind this, and I think we increasingly need philanthropists to come forward and go after it. As I share your term of existential threat, I think if you speak with most educated individuals, antibiotic resistance broadly, antimicrobial resistance will be on everyone's existential threat list but notably of that list, it's the cheapest one that can be solved.Eric Topol (19:09):Well, you're showing that you've got the most extraordinary candidates that have been found in decades. So that says a lot right there.Jim Collins (19:18):Important step, yeah. So I think we've got additional innovation needed in the models to address this, and until we have that address, then this interesting discoveries we and others are making will not get to patients. So we need to have that additional next step to close this gap.Eric Topol (19:32):Now, obviously this has relied on AI and the progress that's occurring in AI to enable some of your work. I am fascinated by the use of AlphaGo. Most times we hear about using AlphaFold2, but you actually use AlphaGo the original game DeepMind work but there also was the progress of from deep neural networks to transformer models and your ability now to basically exemplify what can be achieved in drug discovery using the progress in multimodal AI. Is this something that is making a difference for you and your group?Jim Collins (20:13):It is, it's huge. I think it's very early in terms of the introduction to these new tools extensively within drug discovery. Machine learning has been used for over two decades, both supervised learning and unsupervised learning. Now we're seeing groups coming in for the deep learning efforts. It's largely data-driven so in fact, with the exception of sequences, most of drug discoveries not yet big data in the big data phase, but it's beginning to change. It's truly been transformative for us, so we've used graph neural nets primarily for our discovery efforts. We're now beginning to incorporate language models as multimodal models along with the graph neural nets as well as to see to what extent pre-trained language models. For example, mobile form from IBM, which was trained on PubChem and the ZINC database could be fine-tuned with small amounts of training data, screening data from a resistant organism.(21:06):Third, and I made an indirect allusion already, we've been looking at using transformers and genetic algorithms in older form of AI tech for design of novel antibiotics so we've been now looking to see using fragments as a starting base, using trained models to build out novel antibiotics that can then be de novo designed. One of the big challenges in that space is how do you synthesize these molecules? So you have both the challenge of can you come up with a small number of steps that enable you to synthesize? And second is could you find somebody to synthesize them? And each of those remains very big challenges. My faculty colleague here at MIT, Connor Coley's probably one of the world leaders, easily, he's in using AI to calculate the synthesized ability of a molecule, but we still have gaps in that we don't have the community resources to make most of what we come up with.Eric Topol (21:58):Well, one of the features of large language models that David Baker at the Protein Design Institute exploited is its ability to hallucinate and come up with proteins that don't exist. Can you do the same thing in your design of antibiotic candidate molecules in a way that is not worrying about the synthesis, but just basically the hallucinatory behavior of large language models?Jim Collins (22:28):It's interesting, so yes and so David's work is marvelous and we're big fans and longtime friends of his work. Yes, so we've been driving these models truly to do de novo synthesis. So based on what has been learned, can you put together molecules that one's never seen before? We're doing it quite successfully. It becomes interesting from the hallucination in that it comes out really more of these models making stuff up and ours it's really more directing the hallucinations, right? Really looking to see can we harness the imagination of the models in order to move them forward in very creative design manners.Eric Topol (23:08):Yeah, I mean, I think most people have a negative connotation of hallucinations, but these are the smart variety potentially. This in many ways you could say there's so much crowded interest in the drug discovery AI world, but what you're doing now seems to be setting the pace in many respects for others to follow such remarkable advances in a short time. By the way, we'll link to that TED talk you gave in April 2020, where in seven minutes you went over what you're doing of course and who would've, and that was in 2020 that where you'd be three or four years later, and that was what you're going to do over the next seven years with seven new classes of new antibiotics. Now, before we wrap up, it isn't just that you're an AI antibiotic, you and your team antibiotic discover and doing compressing in time, what has taken decades that you're doing in months, but also you are a father of figure in the field of synthetic biology and I wonder if you, before we wrap up, can explain not only what synthetic biology is since a lot of people don't really know what that means, but how does that dovetail with your efforts in what we've been discussing?Jim Collins (24:33):Yeah, thanks. So synthetic biology is a relatively new field that's bringing together engineers with biologists to use engineering principles to model design and build synthetic gene networks and other molecular components that can be used to rewire and reprogram living cells and cell-free systems, endowing them with novel functions of a variety of applications. So the circuits, these programmable cells are impacting broad swats of the economy from food and water to health and sustainability of bioenergy to human health. Our focus is primarily human health and we've been advancing the idea that you can reprogram bacteria to detect and treat bacterial infections. So we've shown you can use this to go after cholera, we've shown you can use is to prevent antibiotic induced gut dysbiosis. We've also used synthetic biology to create whole new classes of diagnostics. For example, paper-based ones using RNA sensors for Ebola, for Zika and for Covid.(25:33):How it dovetails with what we talked about is that I think there's a great opportunity now to turn to AI to expand synthetic biology, both expanding the number of parts we have to re-engineer living systems as well as to better infer design principles that can be used to reprogram rewire living systems. We're beginning to advance, we're not yet at the SynBio AI project phase, but very early efforts and David's dominating the protein space and we and others are beginning to now movement to the RNA space. So to what extent can we create large libraries of RNA components, train language-based models, structure-based models that can both predict RNA structure more critically predict RNA function and as you know from your marvelous work and what's happening is that it's the exciting age of RNA of getting after RNA therapeutics, be it mRNA or CRISPR related and we still need to get better at our ability to design those therapeutics with certain functions in mind, and we think AI is going to help get us there faster.Eric Topol (26:34):Well, speaking of that, there was a paper this week in Cell by McCafferty and colleagues, and one of the sentences that struck me, we are standing on the cusp of a new era of biology, where the integration of multimodal structural datasets with multiscale physics-based simulation will enable the development of visible, virtual cells. This is yet another lineage or direction of where we're headed with AI, but this fusion of the advances that are occurring right now in biology with AI that extend in many different directions, it's so exciting and you are basically nailing it. I mean, you're putting points on the board, Jim, and I just have to say, I'm blown away by what you've been accomplishing in a time space that's so incredibly compressed.Jim Collins (27:40):Oh, well thanks. Well, you think back to the early days of molecular biology and physicists like Francis Crick and Max Delbrück played huge pioneering roles and then in the second wave in the eighties or so, you had other physicists like Walter Gilbert playing big roles. I do think physicists computer scientists are starting now to play big roles in this next phase where we need tools like AI in order to really grapple with and harness the complexity, both the biology and the chemistry that underlies living cells. They can kind of expand our intuitions both to understand and to really control these systems for good going forward.Eric Topol (28:15):Well, you're doing it and we're be cheering for the success of these drugs that you've come up with in the clinical trials as they go forward because they look so remarkably promising. You even highlighted ways that I wouldn't have envisioned where they could make a difference, so we'll follow your work, you and your colleagues with great interest. Thanks so much for joining,Jim Collins (28:37):Eric, thanks for having me. Enjoyed our conversation.******************************************************************************Thanks for listening to Ground Truths. Please share if you found this podcast informative.Full video interview will post here Get full access to Ground Truths at erictopol.substack.com/subscribe

In this podcast, I'm going to share a recipe for a powerful, natural antibiotic drink that you can make at home. The overuse of antibiotics is a major issue in the United States. Overuse of antibiotics leads to antibiotic resistance. This means that the microbes that are not killed by the antibiotics become stronger and resistant. When you take antibiotics again, they don't work as well anymore. Antibiotics do not kill yeast or viruses, but they do kill good microbes that keep the yeast at bay. This is why a common side effect of antibiotics is an overgrowth of candida or yeast. Weaker antibiotics like penicillin and tetracycline work by slowing the growth of microbial reproduction. Stronger antibiotics like Cipro and Levaquin come with strong side effects and a black box warning. If you have to take stronger antibiotics, always take magnesium, vitamin E, and probiotics along with them. After taking antibiotics, it could take weeks or even years to get your original microbes back. Because 80% of your immune system is your microbiome, this can have detrimental effects on your natural immunity. Antibiotics naturally come from molds and other microorganisms found in the soil. These natural compounds have anti-inflammatory effects, antimicrobial effects, anti-diabetic effects, and anticancer effects. Here is the recipe for a natural antibiotic drink that should be taken at the first sign of a cough or illness: •3 cloves garlic •90 drops Echinacea extract •1 whole organic lemon (peel included) •1 tablespoon apple cider vinegar •1 tablespoon raw honey •16 ounces water Blend all ingredients for about 45 seconds. Drink ⅓ of the mixture 3 times per day. If you're in the middle of an infection, do this for the duration of the infection. You should notice a diminishing of symptoms, and you should sleep better. Also, take 50,000 IUs of vitamin D3 and 100 to 150 mg of zinc to boost your immune system. DATA: https://www.ncbi.nlm.nih.gov/pmc/arti... https://pubmed.ncbi.nlm.nih.gov/16099... https://www.ncbi.nlm.nih.gov/pmc/arti...

Il 17 dicembre, per la seconda volta in poco più di un anno, gli elettori in Cile hanno respinto un nuovo progetto di nuova costituzione. Il 9 dicembre a Venezia sono stati arrestati 28 attivisti di Extinction Rebellion che avevano tinto di verde l'acqua del Canal Grande per protestare contro il fallimento della Cop28. CONElena Basso, giornalista, da Santiago del CileAlice Facchini, giornalistaLINKCile: https://www.youtube.com/watch?v=AiDBRUp1LIEVenezia: https://www.dire.it/09-12-2023/991076-video-foto-navigli-venezia-bologna-torino-verde-acqua-fiumi-cop28-extinction-rebellion/A Cipro le startup trovano casa, Damien Leloup, Le Monde:https://www.internazionale.it/magazine/damien-leloup/2023/12/14/a-cipro-le-startup-trovano-casa: Le tre serie tv dell'anno: Succession (Sky)The bear (Disney+)La legge di Lidia Poet (Netflix)Se ascolti questo podcast e ti piace, abbonati a Internazionale. È un modo concreto per sostenerci e per aiutarci a garantire ogni giorno un'informazione di qualità. Vai su internazionale.it/podcastScrivi a podcast@internazionale.it o manda un vocale a +39 3347063050Consulenza editoriale di Chiara Nielsen.Produzione di Claudio Balboni e Vincenzo De Simone.Musiche di Tommaso Colliva e Raffaele Scogna.Direzione creativa di Jonathan Zenti.

HR1 Dr. Scott: Stem Cells Revolution. Hurt by Cipro, Levaquin, Fluoroquinolone Antibiotics? 11-29-23 by John Rush

La crescita del Pil dell'Italia dovrebbe rallentare. Il Pil dovrebbe aumentare dello 0,7% sia nel 2023 sia nel 2024 prima di una lieve ripresa dell'1,2% nel 2025: è quanto emerge dalle Prospettive economiche dell'Ocse presentate oggi a Parigi. Un dato che, come avevano già evidenziato altre istituzioni in questi mesi, rimane molto al di sotto dell'1,2% per il 2024 scritto nella Nadef dal governo. Sul rallentamento dell'Italia incide anche la recessione tedesca, la Germania dovrebbe chiudere il 2023 con un -0,3%, con effetti molto pesanti soprattutto nelle regioni del Nord. Ad esempio se a livello nazionale Berlino vale il 12,4% del nostro export, nella provincia di Brescia si arriva oltre il 20%, addirittura quasi ad un quarto delle vendite estere nell area vasta dei metalli, architrave della manifattura locale. Acciaierie e fonderie, componentisti e subfornitori che sul mercato tedesco sviluppano 4,4 miliardi di vendite, record tra tutti i territori che nel 2023 non verrà avvicinato neppure da lontano. Nel secondo trimestre, le vendite manifatturiere verso la Germania sono crollate del 18%, calo di oltre 200 milioni. La discesa dei listini per il rientro dello shock energetico ha un peso ma a ciò si aggiunge una frenata anche nei volumi, minori acquisti da parte di una manifattura tedesca ampiamente al di sotto dei valori pre-Covid. Tanto nell industria che nelle costruzioni, frenata quest ultima che ha ricadute negative ad ampio raggio. Se su base nazionale nell area dei metalli il calo è di 1,5 miliardi, Brescia da sola perde 260 milioni. Questi timori sono stati registrati da un analisi di Confindustria Brescia tra 150 aziende, oltre nove miliardi di ricavi. A crescere è solo il 7%, mentre nel 52% dei casi si segnalano volumi invariati e il 41% indica invece una frenata dell export verso Berlino. E per quasi due imprese su dieci si tratta di un calo di oltre il 20%, con gli esiti peggiori tra chimica, gomma-plastica e soprattutto metalli e metallurgia. Approfondiamo il tema con Luca Paolazzi, advisor di Ceresio Investors, presidente e direttore scientifico della Fondazione Nord Est.Dl energia, dall'addio al mercato tutelato ai rigassificatoriIl Cdm l'altro giorno ha approvato il decreto energia, che promuove il ricorso alle fonti rinnovabili e il sostegno alle imprese energivore. Non verrà prorogato, invece, il mercato tutelato per elettricità e gas. Le tariffe in bolletta fissate dallo Stato e non dalla concorrenza, infatti, finiranno come previsto dalla legge: il 10 gennaio 2024 per il gas e l'1 aprile per l'elettricità. Nel Decreto legge Energia, approvato dal Consiglio dei ministri, non c'è traccia del rinvio di cui si era parlato negli scorsi mesi. Questo siginifica che circa 5 milioni di famiglie su un totale di 9,5 milioni di famiglie e partite Iva dovranno sottoscrivere entro la metà dell anno prossimo un nuovo contratto sia per la fornitura di metano sia per l elettricità. Il Ministero dell'Ambiente e della sicurezza energetica Pichetto Fratin ha fatto sapere che istituirà un tavolo per studiare modalità di passaggio "morbide" e non traumatiche per le famiglie. "Il 10 gennaio ci sono le gare. Faremo delle valutazioni rispetto ai clienti vulnerabili, pensando per loro a una metodologia diversa. Con Arera stiamo definendo le modalità di attuazione", aveva già anticipato il ministro dell'Ambiente Gilberto Pichetto Fratin sul futuro. I clienti interessati dal passaggio hanno già ricevuto o riceveranno a breve dai rispettivi venditori una lettera in cui sono illustrate le possibili offerte, oltre ad alcuni chiarimenti sulle prossime scadenze. Come ricorda il ministro dell'Ambiente e della Sicurezza energetica, Gilberto Pichetto, Il decreto energia approva anche: una norma per considerare di pubblica utilità, indifferibili e urgenti, le opere per la costruzione e l esercizio di terminali di rigassificazione di gas naturale liquido on-shore, nonché le infrastrutture connesse: una norma importante per impianti come Porto Empedocle e Gioia Tauro". Quest'ultimo, nello specifico, è stato progettato da Sorgenia e Iren. L opera può dare un contributo di 12 ai 16 miliardi di metri cubi annui di importazione di gas, pari a quasi al 50% del totale dell importazione che un anno fa avevamo dalla Russia. Torniamo a parlarne con Luca Dal Fabbro, Presidente del Gruppo Iren.Viaggio nei consumi. Percassi Retail gestisce Nike e Starbucks. Commercio al dettaglio in calo a settembre, ne risente maggiormente l'acquisto onlineTorna il nostro appuntamento con Viaggio nei consumi, fra il maggio e il luglio della scorsa stagione abbiamo infatti fatto una serie di interviste ai principali attori del largo consumo come Conad, McDonald's, Ovs, Yamamay, Piquadro, Triboo.. etc. Riprendiamo il percorso di Viaggio nei Consumi con uno dei più grandi marchi per la gestione e sviluppo delle reti commerciali e del retail dei più importanti brand. Percassi Retail gestisce in Italia e all'Estero brand come Nike, Lego, Victoria's Secret, Saint Lauren, Gucci e Starbucks. Proprio di Starbucks è licenziatario unico e gestisce i 31 negozi presenti in Italia. Percassi Retail ha un fatturato (anno '22) di 376milioni di euro, di cui 261 in Italia e 115 milioni all'estero. Presenza in 6 Paesi: Italia, Francia, Spagna, Portogallo, Grecia, Cipro. 181 store, di cui 132 in Italia e 49 negli altri Paesi (Francia, Spagna, portogallo, Grecia, Cipro). 2.900 dipendenti di cui 2.100 in Italia. Sono tuttavia di ieri i non entusiasmanti dati Istat sul commercio. Le vendite al dettaglio in Italia a settembre sono in calo, scendono dello 0,3% in valore rispetto al mese precedente e la flessione raddoppia allo 0,6% in volume, secondo i dati Istat. Approfondiamo il tema con Matteo Morandi, Amministratore Delegato di Percassi Retail e di Starbucks Italia.

Quali sono le principali rotte migratorie che percorrono i migranti per arrivare in Italia e in Europa? I percorsi principali sono 5 e partono da Africa, e Medio Oriente: le rotte del Mediterraneo centrale, occidentale e orientale, e le rotte dell'Africa orientale e occidentale.  In base alle informazioni dell'Alto Commissariato delle Nazioni Unite per i Rifugiati, aggiornate al 10 settembre 2023, finora quest'anno sono arrivate in Unione Europea 165.669 persone, di cui 115.037 in Italia, 24.358 in Spagna, 22.921 in Grecia, 3.082 a Cipro e 271 a Malta. Learn more about your ad choices. Visit megaphone.fm/adchoices

Fluoroquinolones such as Cipro, Levaquin and Avelox are antibiotics commonly used to treat or prevent serious bacterial infections such as sinusitis, bronchitis and urinary tract infections. According to the Centers for Disease Control statistics, American doctors wrote nearly 30 million fluoroquinolone antibiotic prescriptions in 2016.  A 2016 FDA safety review stated that fluoroquinolones are associated with disabling and potentially permanent serious side effects that can occur together. These side effects can involve the tendons, muscles, joints, nerves, and central nervous system. Fluoroquinolone toxicity can cause severe mitochondrial damage in the body. This condition is commonly misdiagnosed as lymes, MS, arthritis, fibromyalgia among others.  Kiley Woodland is a singer songwriter and recording artist and was opening for KISS with her band shortly before she was given cipro, one of the most commonly prescribed antibiotics, which ended up causing such severe debilitating side effects it put her in a wheelchair.  Kiley has since started sharing her journey to educate others on the dark side of fluoroquinolone antibiotics that often no one is told about. In this episode she talks about how fluoroquinolones harm the cells, the "fluoroquinolone bomb going off", where genetics and nutrient deficiencies play in to a recovery plan, and the two most important minerals that are chelated out with fluoroquinolone toxicity. Her Instagram: https://www.instagram.com/celebratethelittlewins/ Her upcoming website: www.celebratethelittlewins.com My website: www.matt-blackburn.com Mitolife products: www.mitolife.co Music by George Henner https://georgehenner.bandcamp.com/  

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Chris: Hi doctor Cabral. Absolutely love anything you are doing for the world. I just have a question regarding silica dust. I work in construction and although I do everything I can to prevent inhaling the dust, it is extremely hard to keep myself from breathing in some dust every day. I know how deadly silicosis can be and was wondering if there were ways that I could help rid the body of any built up silica dust in my lungs? I was also wondering if there was a lab/test that would indicate if I had high levels of silica in my body? Thanks for everything you do Chris   Tamara: HI DR. Cabral Can you tell me is it safe to eat off of Cornell brand plates and bowls? Thanks for all you do!   Amy: Hello Dr. Carbral! I have a Oura ring, but I feel like I'm not using it to its full capability. Where is the best place to find info on healthy parameters (HR, HRV, sleep time, etc)? Thanks!   Anonymous: Hi doc! Been gung ho on natural health for about 5 yrs. Threw in 100% with you about a year ago after binging your podcast for a year. Been through many of your protocols with little progress with my gut, still100% committed to the protocols & living a healthy lifestyle. I struggle a lot with stress anxiety & low mood. I had a 6in fibroadenoma removed from my left breast in 2014 & lately I feel like it's coming back. Large lump on the back of my left shoulder for 10 yrs. Also within the last year I've grown a mobile grape sized lump on the back of C6. Gut lymph dumping grounds perhaps? Been working so hard following everything to the T, so why is my gut not healing & what's with all these lumps especially if the body regenerates within a year? Stress? I get so frustrated & scared. Thanks!   Nicole: Hi! I've suffered from a strange vibration in my chest that comes with each heartbeat. It started a few months ago & initially only in the evenings. Now I'm having it most of the day except while lying down & resting. More recently I've also developed some random come & go twitches in my leg, eye lid, arm & vibrations that come & go in my ankle and hip. I've seen doctors, run tests of all sorts including HTMA & all look fairly good. I've been to a cardiologist who after doing testing diagnosed me with mild mitrial valve prolapse, mild regurgitation & mild mitrial valve thickening. He says he's not concerned & I shouldn't be having these symptoms from it. My thoughts are possibly my nerves have become sensitive due to recent stresses & maybe dysautonomia? What are your thoughts on this?   Aly: Hi Dr. Cabral, is it possible to heal from Fluoroquinolone toxicity, or is this something that can permanently damage mitochondria and therefore something that has to be managed for the rest of my life? I was disabled by Cipro for 6 months, and I can now walk short distances. I still have tendon and ligament damage in my neck, elbows, knees and Achilles. I'll do anything to heal--hot and cold therapy, supplements, morning sunlight, diet changes, and more. Eager to hear your thoughts on this!   Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/2661 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Ieri sono stati evacuati dal Sudan 36 australiani e le loro famiglie con un volo della Royal Australian Air Force diretto a Cipro.

Hour 4: During the commercial break Boomer & Gio were signing players' jerseys from the Riptide game. They are going to be auctioned off. They were game worn and not washed and they smell. An Iowa wrestler lost and his mom got so angry and frustrated she took her glasses off and slammed them down. A caller is having a good time for himself telling us he fed alka-seltzer to seagulls and watching them die. Good times. Jerry returns for an update and starts with FDU's magical NCAA run coming to an end last night. St. Johns met with Rick Pitino last night. Gio just wants five really good years from the 70 year old Pitino. Jerry has audio from the WBC games from this weekend and spring training. Former Packer LeRoy Butler said, ‘y'all ain't winning no Super Bowl' to the Jets fans on TMZ. The Rangers beat the Predators 7-0, scoring six of those goals in the first period. In the final segment of the show, Gio wonders if the Aaron Rodgers deal will really take until June 2nd. Could the drug Cipro be to blame for the Edwin Diaz injury? A caller wants Gerry McNamara to coach at St. Johns instead of Rick Pitino.

Hour 1: Boomer is feeling a ‘Garden Party' with both the Knicks and Rangers playing well. Regarding the Aaron Rodgers situation, Boomer said it's different with the Packers since they don't have an actual owner, so there's nobody for Woody Johnson to call to move it along. Boomer said Aaron Rodgers will wear #8 or #10 and will not wear #12. Jerry is here for his first update but first a Happy Birthday to him. He turned 49 yesterday. He starts with audio from the NCAA tournament over the weekend including FDU's loss last night. Reports say Rick Pitino is in very serious talks with St. Johns to become their next head coach. The Memphis Grizzlies will not be staying on the road as often as they were, thanks to the Ja Morant gun brandishing situation. He ruined it for all of his teammates. DJ Stewart hit for the cycle in Spring training for the Mets. John Sterling has the call of Aaron Hicks making a great catch in the outfield. Aaron Boone talked about getting clarity with the roster. The Rangers scored 6 goals in the first period and had no problem beating the Predators. In the final segment of the hour, Gio is excited as it seems like Rick Pitino will be the next Head Coach at St. Johns.  Hour 2: We talked about the World Baseball Classic and the players' love for the game and to play for their countries. Players said they would rather win the World Baseball Classic for their country than a World Series for their team. There are conflicting reports as to what OBJ wants to join an NFL team. The Jets and Giants still seem to be in the mix for Odell. The Vikings are now rumored to be in the mix for Lamar Jackson, as are the Patriots. Lamar will go live on his YouTube channel to talk about what's going on with him. Boomer seems like he has something to tell us about the Jets and Aaron Rodgers but he doesn't want to jinx anything so he's not sure if he should say anything. Jerry returns for an update but first Boomer says Aaron Rodgers is not wearing 12 because he understands what it means to the Jets. He is also very aware of the finances and says he will do what Brady did with the Bucs, leaving some money on the table for other players. Boomer said Rodgers is going to come here and he's ‘going to be an assassin'. Jerry starts with audio from the NCAA tournament and the end of FDU's run. The Nets have now dropped three straight. Brandon Nimmo is feeling better from his ankle/knee injury and hopes to be ready by opening day. Aaron Boone talked about injuries at the WBC. The Rangers scored six goals in the first period and had no problem with the Predators. In the final segment of the hour, Boomer went to the Riptide lacrosse game on Saturday night. He was quite impressed. Boomer did not go on with Peter Schwartz at halftime.  Hour 3: Gio was annoyed by a discussion on ESPN where someone said ‘Aaron Rodgers is the Kyrie Irving of the NFL'. Boomer said the Jets are not giving a number one pick for Aaron Rodgers. We also talked more about the Vikings being a dark horse team for Lamar Jackson. Jerry returns for an update but first we talked more about the Packers not really having an owner. LeRoy Butler was on with TMZ and said Aaron Rodgers may not gel with the Jets. He also said the Jets aren't going to the Super Bowl. FDU's magical run is over as they did not make it to the Sweet 16. Rick Pitino will most likely be the next Head Coach at St. Johns. Jerry had audio from Yankee spring training and Team USA for the World Baseball Classic. The Rangers scored six goals in the first period and beat the Predators 7-0. We have audio from C-Lo's overnight show where he made it seem like Bill Bradley had passed away. In the final segment of the hour, Gio talked about his fishing trip to Florida. He was using his Bobby Approved app to find snacks in Publix when he was down there. We also talked more about the Jets and Aaron Rodgers. A caller is blaming Joe Douglas for ‘putting all his eggs in one basket'. But Gio said he did, and it worked. The Jets are getting Aaron Rodgers. Gio said his friend told him that when he was a kid they would give alka-seltzer to seagulls and they would explode.  Hour 4: During the commercial break Boomer & Gio were signing players' jerseys from the Riptide game. They are going to be auctioned off. They were game worn and not washed and they smell. An Iowa wrestler lost and his mom got so angry and frustrated she took her glasses off and slammed them down. A caller is having a good time for himself telling us he fed alka-seltzer to seagulls and watching them die. Good times. Jerry returns for an update and starts with FDU's magical NCAA run coming to an end last night. St. Johns met with Rick Pitino last night. Gio just wants five really good years from the 70 year old Pitino. Jerry has audio from the WBC games from this weekend and spring training. Former Packer LeRoy Butler said, ‘y'all ain't winning no Super Bowl' to the Jets fans on TMZ. The Rangers beat the Predators 7-0, scoring six of those goals in the first period. In the final segment of the show, Gio wonders if the Aaron Rodgers deal will really take until June 2nd. Could the drug Cipro be to blame for the Edwin Diaz injury? A caller wants Gerry McNamara to coach at St. Johns instead of Rick Pitino.