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The Manhattan Transfer will be ringing in their 50th anniversary with all kinds of goodies. A symphony album, a documentary and a box set. Proud Member in Excellent Standing, Cheryl Bentyne joins us with behind the scenes insights into crafting harmonies both on and off the stage. She also shares her Cancer battle and recovery journey and her inspiration to bring healing to others through her podcast, I Sing The Body. Plus Fritz and Weezy are recommending Bosch, Letters to America by Willie Nelson, Mr. Graham and the Reasonable Man from Radio Lab, This is Pop and The Boy Band Con. Path Points of Interest:Cheryl BentyneCheryl's Page on the Manhattan Transfer SiteManhattan TransferManhattan Transfer Songs on YoutubeTrickle TrickleBoy From New York City Operator Birdland Manhattan Transfer Playlist:Cheryl's Podcast, I Sing the BodyBosch Final Season - Amazon Prime Willie Nelson's Letters To America - by Willie NelsonMr. Graham and the Reasonable Man from Radio Lab and More PerfectGraham v. Connor Case on WikipediaRadiolab PodcastThis is Pop on NetflixThe Boy Band Con: The Lou Pearlman Story
Episode Notes The host Margaret Killjoy can be found on twitter @magpiekilljoy or instagram at @margaretkilljoy. You can support her and this show on Patreon at patreon.com/margaretkilljoy. The guest Guy recommended people support the Gray Coast Guildhall on Patreon to support a small town community space: https://www.patreon.com/graycoastguildhall Transcript Because this was a last-minute episode, this is a machine-generated transcript to serve as a placeholder while our transcriptionist can provide a proper one. SPEAKERS Margaret Guy Margaret Hello, and welcome to live like the world is dying your podcast for what feels like the End Times. I'm your host, Margaret killjoy, and I use she or they pronouns. Normally I do this like whole intro thing that I record after the conversation. But this is a special, a special episode that I'm just doing as quickly as quick turnaround as I can because of what's going on in the Pacific Northwest with unprecedented heat. And I want people to have information as soon as possible. So please forgive audio quality. on my end, I'm recording this from the best place I had access to internet, which is right next to one of the busiest intersections in all of the tiny town of Asheville, North Carolina. But anyway, this podcast is a proud member of the channel zero network of anarchist podcasts. And normally I put in a jingle here, but I'm not going to instead, you should just go to channel zero network. I don't even know the website, you just Google it. I mean, come on, who's actually going to type in URL and you can just type things into the search bar. Go check out the channel zero network, there's a ton of shows that might interest you. Okay, so would you like to introduce yourself with your name and your pronouns? And then a bit of your background as relates to heat related illnesses? Guy Yeah, thank you. Thanks for having me on. My name is Guy, I use he him pronouns. I live up in the Pacific Northwest on the Olympic Peninsula. And my background related to this, I have been a wilderness educator and backpacking guide for many years, especially working down in the Grand Canyon for several years. So a lot of exposure to heat there. And I also instruct wilderness medicine courses. And so I teach and think about bodies and how bodies adapt to stress, particularly heat stress in this context. Yeah, Margaret that's me. Hurray. I'm so glad that your skill set is about to become very useful away from the Grand Canyon in the Olympic Peninsula. The rain forest that I believe is not is it? Is it normal for you all to have 109 degree weather? Is that abnormal? Guy That is definitely abnormal. Yeah. We sometimes will will cross 100 or triple digits over 100 for one or two days in the summer, usually in late July or August. I cannot remember a time when we hit 108 degrees, and certainly not in late June. It is pretty hot. Margaret Yeah, I've I'm I'm from the Mid Atlantic. And now I live in the south on the east coast. And I've The only time I've been in. I mean, I've been in triple digits. I don't think it ever got hotter than 103 104 the whole time I was growing up. And only time I've been in 110 degree weather was in Death Valley. So I'm worried about you all. So that's why I'm I don't Yeah, we're going to talk at a later point with someone that you co teach with about more wilderness first aid. But it seems like wilderness first aid is suddenly might become urban first aid in a way that we're not. I'm not really used to and maybe you're not really used to. I guess to start with, do you want to talk about? Like, what are the dangers of heat? Guy Yeah, so I'll preface this by saying a couple of things. The first is the human The human body is actually really adaptable and resilient if it has time to adapt to a changing environment. So people can handle really extreme heat, if they have time, to climatized to it. But if we get these big spikes of heat coming in a place where people aren't used to it, we're jumping from the mid 80s, one week to 108 another week, then that becomes a lot more stressful on body. And then add on to that right up here in the Pacific Northwest as a culture as a society we're not adapted to experience. Most people's houses aren't particularly well insulated, because in general, it's a fairly temperate climate. So there's just not the either the time to adapt on a physiological level or to adapt our environment to really manage and handle this heat. So that said, a few different things happen when we we get too hot, so our body, right we we sweat, we produce sweat and that's the primary way that we cool ourselves off and evaporation is is actually a very effective cooling mechanism. If we have an up sweat, and particularly if there's a breeze that is able to allow that evaporation to to continue to cools off, as our body gets too hot, and we start to lose our ability to thermo regulate, we end up seeing a lot of different side effects. And so we used to think of this really clear progression from what we call heat exhaustion, heat stroke. And now it seems more like there's just a lot of different clusters of symptoms that appear when people get too hot. So things like nausea, vomiting, feeling really tired, feeling a little bit disoriented, feeling irritable, some muscle cramps, particularly related to exercise, sweating, and excessive sweating, but then also maybe some more like chills or pale, pale skin, clammy feeling, as our body just doesn't tolerate the heat extremes very well. And all the symptoms, all those symptoms are unpleasant, but fine. And the real danger is when our internal temperature starts to cross 104 or 105 degrees Fahrenheit. And at that point, our brain actually starts cooking. And so we see our mental process change, we don't think as clearly our personality changes, and we're actually doing long term damage to our brains, and they won't survive that for very long. Margaret When you say very long, like what are you talking about there, like five minutes an hour, Guy oh, no, definitely in the in the hours realm. But the longer that persists, the more damage the more permanent damage can be done to our to our brain and to our bodies. Depends on the heat extreme. But so and then once we lose that, once we start losing that ability to thermo regulate altogether, instead of maintaining a temperature that's elevated, but not too high, we just kind of start to run away, and we can't cool off at all. And then and then we need help from from other people, we need a change of environment, we need to be cooled down really, really quickly. Margaret One of the I asked, asked social media right before this interview, like corner what what advice people had and also what questions people had. And the thing that you just talked about, about how we used to see it as heat exhaustion versus heatstroke is very different. That is one of the things that most people were bringing up is like, make sure you know the difference between heat exhaustion and heat stroke with the idea, I guess the prevailing knowledge and what I had known prior to five minutes ago, when you said otherwise, would be that heat exhaustion is the like, Oh, this fucking sucks. And I should probably get somewhere cold real quick. And maybe someone can help me get somewhere. Not real cold, but like colder real quick. Versus heat stroke is like, you know, call paramedic, like get taken to the emergency room or whatever, because you're about to die or something. Right. And you're saying that the line between these two is, is not only not a clear line, but it's not even necessarily a specific progression as much as like, you are just different clusters. Can you tell me more about that? Guy Yeah. So heat stroke, heat stroke is really clear. And maybe that I misspoke. A little bit there. Margaret I might have misheard you. Yeah, yeah, Guy so so heat stroke is very clear. That's when our internal temperatures reached 104 105 are the proteins that our brains start denaturing we start doing we start getting cell death in our brains, and permanent damage. And the easiest way to recognize that in someone is a change in their personality, or change in their thought process and see someone who was previously grumpy and maybe a little irritable, or maybe a little hot, or maybe they were just fine. Now they're saying or doing things that don't make any sense. And that's because their brain is not functioning properly anymore. So heatstroke is a is pretty clearly delineated. The distinction is that there's not necessarily a progression from one to the next you don't necessarily get this long warning sign of heat exhaustion and you're feeling bad and then you feel worse, and then you feel worse, and then it's heatstroke. That happens in some people. But another people it can just go directly to heatstroke without this preliminary experience of feeling a little bit crappy and under the weather and nauseous and faint. Margaret Okay. So what do you do in each of these situations? Whether you're alone, or whether you're with someone who's experiencing these symptoms, like what do you do for someone who's suffering from heat exhaustion symptoms? versus heatstroke? Guy Yeah, so, so in both cases, the problem is that someone is too hot and so the solution is to cool them down. So heat exhaustion This cluster of nausea, muscle cramps, I just don't feel good fatigue, maybe some vomiting, that person wants to be cooled down. So we should get into the shade, we should try to move to a cooler environment change clothes. But we're not necessarily we have time to do that heat stroke, as soon as we see that change in personality, or mentation, we want to cool that person down as quickly as possible. And so the fastest way generally to cool someone down is through some amount of Coldwater immersion. So, throw them into like, throw them in a leg, but probably not throw them because if they have this altered mental status, they can't think as well, we're worried about their ability to write but get them in, get them in running water, get as much of their body in the water as we can while protecting their airway, to cool them down quickly. And if we don't have a big body of water, we can put them in, it's nice and cool, the next best thing is get them as wet as we can, and then fan them because that sort of cooling consumes a huge amount of energy, which then cools the body fairly quickly. So if you think about you get your hands wet, they don't feel that cold, and then you get a breeze moving across your cold hands or your clothes are wet, you get cold really fast, because evaporation takes more energy, then I'm simply being immersed in water. Margaret Okay, how does, um, how does being in a human environment, impact evaporative cooling and dealing with this sort of crisis? Guy Yeah, humidity is a real challenge here. And that's the thing that we're fortunate about here in the Pacific Northwest, where summers are usually pretty dry. Okay. But the the more humid the air gets, the less effective evaporative cooling will be. And that means both that just getting someone wet and fanning them won't work as well. But it also means that our body's natural mechanism for cooling, which is sweat also doesn't work as well. And so there's this concept of the wet bulb temperature, which is rather than looking at what is the temperature on the thermometer to put a thermometer inside a bulb and you cover it with a damp cloth. Now they have mean fancier tools to do this now, but the principle is the same. covering a soaking wet cloth. And then they measure what is the temperature that that thermometer reads. Margaret When you have a bowl or a bulb. So yep, wet bulb temperature bulb, oh, you get the Oh, you put it inside a light bulb is that it? Guy any any bulb any any any spiracle object, right? It's covered in a damp cloth. Okay? If the humidity is lower than 100%, the temperature that that thermometer reads is going to be lower than lower than the air temperature, right, because there's some amount of evaporation which is cooling the air inside. Margaret Interesting, Guy okay. And so this is a way for us to understand what the actual threat of a any particular temperature is. Because once we get to 100% humidity, the temperature inside that bulb is going to be exactly the same as it is outside because there's no longer any evaporation occurring and no longer any cooling. And the challenge there. And so this is this is how wet bulb temperatures are measured. You can look up tables that will tell you relative humidity and temperature and you can find the wet bulb temperature at that intersection. And once we hit about 90 degrees at 100% humidity, or a 90 degree wet bulb temperature, which we could get with either higher higher temperature and lower humidity or lower temperature and higher humidity. Once that wet bulb temperature hits about 90 degrees, humans can no longer effectively function in any kind of meaningful physical exertion outside. Okay, and even completely at rest. Without any exertion. People will start to die within hours once you hit about 95 degrees. wet bulb temperature, Margaret which is what it would be at like 100% humidity if it was 95 degrees out. Exactly. Yeah. As someone who the inside of my house is regularly 90 to 95% humidity during the summer. I know I'm not supposed to be worried about myself today. Still mostly worried about y'all. But it actually is changing a little bit my my sense of the heat that y'all are facing. Yeah. What I mean okay, so if it's like, like, do you have a sense of like when they're like it's gonna be 109 degrees 111 degrees 116 degrees in business. cific Northwest this weekend, you know, or maybe you're listening to this three weeks later, I don't know, whatever. But do you have a sense of like, what kind of wet bulb temperature that is likely to be for people? Guy Yeah, so so our humidity usually here in the summer ranges between like 20 and 40%, particularly high. And so I ran a couple of numbers before this show, and who was looking like, this Sunday, when we're supposed to hit about 108 degrees during the peak of the day, that'll probably equate to something around a 75 or 80 degree wet bulb temperature, which doesn't sound that hot, but actually is is pretty darn hot and really hard for the body to tolerate. Margaret And so what that means is not everyone is fine, it means that the means by which we can fight this with like, cold water immersion, and fanning and things like that actually have a chance of working is what you're saying. Guy Exactly in in places with low humidity, water, and evaporation works really well to pull you down. The problem with this, and this is what a lot of climate scientists have been warning about for a long time is that the tropical parts of the world, as we start to get increases in temperature, which are already close to 100% humidity, during that season, we'll get so hot that there's no effective way to cool down. And then we'll see a lot a lot a lot of heat related deaths, because these parts of the world also don't have air conditioning. cooling is completely ineffective. And so in some ways we're lucky up here so far, because our summers are dry. Margaret Yeah, and there's, I mean, a lot of people listening don't have access to air conditioning. But I, but there's there might be like, you know, I know that some cities are setting up cooling centers and things like that. So there is some access to air conditioning in the northwest, okay. So when you talk about like not exerting yourself and things like that, like you're basically saying, like, basically, because when you exert yourself, your body heats up, and that's bad. So it's like, one of the main things people should do is like, chill the fuck out and like, not exert themselves as much as possible. Guy Yeah, exactly. That's one of the best things that we can do is write we stay out of the sun, as much as possible, try to stay as cool as possible. And just don't do. Don't exert yourself, don't do physical labor. Don't go for runs, try to get out of your job if your job involves heavy, heavy physical labor during these hot temperatures or organized with your other workers, because it's literally putting putting your life at risk. Yeah. To be working in these conditions. Margaret Yeah, okay. And then. So if this kind of not fully covers, but but gets at the idea behind like heat exhaustion, heat stroke. The other the other thing that at least is on my radar to worry about as relates to intense heat is dehydration. And that's kind of a separate threat. Right? Yeah. Can you talk about dehydration, also, our mutual friends as you have a good story about dehydration? Yeah, Guy I have a lot of rants that I could go on about dehydration. And it's it's more evil twin overhydration, also known as hyponatremia. So, so, hydration is important, our bodies function better when we're well hydrated. But luckily, our bodies also have this amazing built in mechanism to help us maintain adequate hydration, which is our sense of thirst. And generally, people should drink when they're thirsty, and they should drink a little bit more if they're exercising or if they're in hot weather. And if you're well hydrated, then you will, you will tolerate heat better and you will be more able to adapt. That said, hydration doesn't prevent heat exhaustion and hydrating doesn't fix heat exhaustion or heatstroke either. The problem is, once you've hit that point, the problem was just that you're too hot and you need to cool down. So it's a separate problem. Exactly. They go hand in hand and do tend to sweat more or lose more fluids in hot weather and need to replace them. The place where people get into trouble. We have this cultural myth of dehydration as the big killer. And like you've probably heard people say hydrate or die and there's all these stories about people who athletes who didn't drink enough water and they died. And that's actually not really the case. Most people stay hydrated enough, most of the time, they are getting dehydrated and they have access to water and then don't have vomiting or diarrhea that's sucking water out of them, they can maintain adequate hydration pretty decently the problem, the area that we actually see a lot more deaths, and a lot more severe illness is the opposite. This this problem over hydration. And so for the last couple decades until well, like through the 90s and early 2000s, there was a lot of rhetoric in sports medicine, about the importance of hydration, and you have to hydrate And drink, drink, drink, and you have to drink Gatorade, and you have to drink electrolytes. Because if you don't, then you're gonna die of dehydration. And actually, what we were doing was people were drinking too much water. And that changes the electrolyte balance in our bodies, and it ends up making our cells swell up. And we started getting swelling in the brain that really rapidly fatal and so most, most of the exercise related deaths like ultra marathoners hikers that we used to think were linked to dehydration. Most of those deaths are actually linked to called hyponatremia. Not enough salt. But the real problem is that you've drunk too much water and you've diluted your salt. Margaret Oh, God, so we're telling people exactly the wrong thing to do. I mean, like all of those other hikers died, so you better drink more water? Guy Yeah, so you're allowed to drink a lot. But when people get these benchmarks, and they hear like, Oh, I should drink, I should drink a liter of water an hour rest drink two liters of water an hour, I should drink a Gatorade at every stop in this race. People are basing their hydration on some outside metric rather than their own body's sense of whether they need fluid or not. Then Then we we tend to see hyponatremia which is much more deadly and much harder to treat than dehydration. So like many other things that Western medicine has done, we have invented a problem where there used to be no, because humans generally are good at knowing what their bodies need and taking care of them. Margaret Yeah. Okay. And like, like, I've never drank electrolytes on purpose in my life. Right? Like, I mean, I drink emergency in the morning, but I think I do it for like vitamins, which might also be bullshit, but I don't know. Um, and people are always like, talking about the importance of drinking electrolytes. And, I mean, this obviously sounds like it ties into it, like, do you avoid hype? hype bone night? ceria I was gonna just avoid pronouncing that actually. But I failed at that. Do you avoid that better? If you are also drinking electrolytes and like eating salty snacks and things like that? Is there like? Like, how, how important are like our electrolytes and all this? Guy Um, so the the answer is twofold. Like many things, so electrolytes are important. We should have salty snacks. And our body needs electrolytes to function. Well. That said, there's just no correlation between drinking electrolyte solutions, and a lower onset of hyponatremia. There's plenty of extreme athletes, ultra marathoners and hot places who are drinking mostly electrolyte solutions. And the real the real risk factor is just the volume of fluid and formed the volume of fluid drunk. So if people like electrolyte drinks, they should drink them. I drink them sometimes. And it makes me feel better, I think. Yeah, but to prevent hyponatremia and we shouldn't think that we're fixing the problem of low electrolytes by drinking electrolyte drinks, because what we're actually doing is just adding too much more fluid to a system that's already over hydrated. Okay, Margaret so just trust your body and drink is this like how like, one of the main things you learn like street medic stuff? Is that just water for everything? Like, you know, it's like chemical weapons and you fix it with water. Now all these great, it's amazing or whatever. So just water and and not too much of it. You should drink a little more, if it's really hot out. salty snacks. Margaret Yeah. Okay. So if you want to focus on electrolytes, focus on salty snacks instead of Gatorade. Guy I mean, you can drink Gatorade, if you like. Sugar and other electrolytes drinks are fine. It's not like they do harm. And if you drink too much of them and you think you're a problem. Yeah. Okay. Margaret Now this is I'm really glad to like be like myth. bussed in or whatever. And like getting past that, like stuff, you can quickly Google on the internet, you know? So I have a lot of other questions from people. This is I think everyone's I already said this, everyone's really worried. Um, what um, and actually, we've been talking about this a lot. We've definitely been talking about things primarily from the point of view of like, not having access to, you know, air conditioning and things like that, right. Oh, actually, before we leave dehydration, what do you do about it? What do you do if both where there is a doctor available and where there isn't a doctor available for both dehydration and the problem that shall not be named? Right? Yeah. hyponatremia overhydration, which is, you call it hyponatremia? And I'll call it over hydration? Guy Right? Go? That's perfect. Um, so dehydration, the problem is those not enough water. And so the solution is they should drink some water. Okay, cool. And the way that and the tricky thing here, right, is that we see people and it's hot out, and they've been exercising, and they say they've got a headache. And they feel kind of nauseous, and they don't feel good. And they're kind of grumpy. And we think, oh, you must be dehydrated, I'm going to give you water. It turns out that the symptoms of hyponatremia are pretty much exactly the same as the symptoms of dehydration with a few options. And so we really actually should be talking to our friends talking to the people we're interacting with and asking them some basic questions. How much water Have you been drinking? Hmm, oh, you had two liters this hour, two liters the hour before liter before that you've had six liters all day and you haven't been doing much. That's a lot of water. Probably shouldn't give you more water. So the very the treatment for hyponatremia. And its mild form is just with hold water. A couple of the things that that we could look for an ask about is someone who's over hydrated was hyponatremia is likely going to have pretty clear urine, and they're going to be peeing a lot. They're going to say, Yeah, I just have to pee all the time. And I really got to drink water, it's really important to drink fluid time pee and all the time. That's a good indication to say you should stop drinking water. Okay, until you're no longer peeing all the time. Dehydration, that person wants water. That's the problem is there's not enough and so they should drink some water. And right, we might also inquire about the year and then they could say I haven't been paying very much it's been really dark yellow, it's been smelly. Those are good indications that someone is dehydrated. On the mild side of, of either of these. It just takes time to fix. If you're if you're dehydrated, you should drink water and rest. And if you're over hydrated, you should rest and stop drinking water. Okay, once once it gets more severe, once we see mental status change, someone is no longer behaving like themselves. That just means that their brain is angry because it's not getting what it needs. Either. It's not enough water. In the case of dehydration, or there's there's swelling and pressure building up because of this hyponatremia And in those cases, that person really needs to go to a hospital. Margaret Okay, what what would the hospital be doing? And I know I'm not like trying to encourage everyone to do everything by themselves, but I feel like it's like useful to like break open the black box with like medical stuff. Guy Yeah, so dehydration, dehydration, they're gonna be rehydrating via IV. Oh, that's a thing that we can do in the back country or without access to a hospital. We don't have IVs but we can rehydrate someone gradually just by drinking water and reducing exertion. And as long as they're not continuing to lose fluid either through sweat or through diarrhea or vomiting then we can probably fix that problem hyponatremia is there's unfortunately not much outside of a hospital setting once it's advanced to the stage someone's mental status is changing. There's not much that we can do and this is one of the reasons it's more fatal dehydration and exercise context Margaret because what if we bloodlet people with leeches Guy Yeah, we can't do that. They will they end up doing it a hospital is giving someone a lot of sailing intravenously to change the the electrolyte balance of their blood, and we just can't do that quickly or effectively, orally so we can definitely give someone salt. But we should know that if they're if it seems like a severe case of hyponatremia or overhydration that really what they need is a hospital intervention. And when should prioritize getting them to that hospital instead of trying to do it ourselves. Because there's just not much we can do. Unless we're, that's right, that's way above my paygrade is, is measuring someone's blood pH and blood chemistry and tinkering with it and injecting different solutions into them. Margaret them. And so this sounds like it. These are problems related to heat. But the but dehydration and overhydration are like more or less directly the problems that we're like specifically worried about this coming weekend, because it sounds like it's like more athletes and things like people who like are fighting can with things in that way? Or is this like, are a lot of the people who are potentially going to die because of a massive heatwave? Is it mostly heatstroke or is it also dehydration and over hydration? Guy Yeah, so so in globally in heat waves, the largest deaths are heat stroke related, or heat stress related and largely in in populations over 60 years of age on this because as, as we age, our bodies just become less adept at thermo regulating, and we're having a hard time adapting the stress. Okay. Certainly, people who are really worried about the heat and think that the solution is to drink a lot, a lot, a lot of water all day long, everybody, a danger of hyponatremia. And certainly as someone who's working outside and sweating a lot and doesn't have access to water, or maybe they're houseless and don't have shelter, and don't have a place to stay cool and don't have good access to clean water. I think we could see dehydration set in and be exacerbated by the heat. The major killers, statistically, are heatstroke. Okay. Margaret What? What should someone who's listening to this who is experiencing homelessness or someone who cares about people who are do besides like, I mean, I guess like, pressure cities into having cooling areas, invite people, if you have AC, like, inviting people in? You know, like, or are there like, specific? Yeah, what would you suggest? Guy Yeah, so there's like, there's a couple, I mean, those are both really important and great. And we should do that. A couple of other things that that we can do, that anyone can do to to adapt to heat better. Right, maintaining good hydration, but not too much salty snacks, all of these things will help with our water balance. Staying in the shade as much as possible, and then trying to have a water source, even if it's just spray bottle and like the ability to spray yourself down. Right, spray your face down, spray your clothes down with a little like $1 spray bottle you get from the dollar store and you fill up and you can just spritz yourself and evaporate and that will pull you down. Right damp bandanas around the neck. On the head, even getting your clothes soaking wet in this more dry environment will work. Because all the evaporation of those clothes, that clothing is going to cool your body quite a bit. Another thing that we see in urban environments is usually with all of the pavement and asphalt and the buildings and the lack of tree cover. We'll see temperatures that are 10 to 15 degrees higher in urban centers than they are in surrounding forests or green areas. And so thinking about is it possible to get to a park is it possible to get to a place with trees that has shade and the plants are through evapo transpiration are helping to cool the area a little more and they're absorbing less heat than these big blocks of concrete that just absorb solar energy and radiate it back out at you know it'll make a big difference. And then thinking about thinking about kind of the mechanisms by which we we gain heat and we lose heat. And so certainly radiation from the sun would heat us up really fast. And we can we can partially mitigate that by wearing light colored clothes that covers all of your skin. So loose fitting long t shirt, long pants, a big hat, you're actually going to be staying cooler and clothes like that then you will be in shorts and a T shirt. Margaret Just humidity affect that I have this like general conception that like dry heat places are all about cover yourself from the sun giving yourself shade through clothes as important whereas like more humid places, more tropical places. It seems like people tend to go with like just less clothes maybe to like really make it as easy as possible to do the little bit of evaporative cooling they can do or am I like just totally off base about this. Guy No, no, I think I think that that's that seems accurate to me. I think that The more humid it becomes, the more difficult it is to stay cool. And the less the problem is like direct solar radiation and more problem is just that ambient air temperature, all of the moisture hanging out in that air that's holding on to heat and then transferring it to you. I've been, I've been lucky to spend Well, I grew up in Indiana, which was very human, but I've been lucky to spend most of my life in places with fairly dry heat, which I much prefer. Margaret Yeah, like, I'm just coming at this, like entirely from this, you know, we refer to it is like, Oh, it's just the Baltimore soup, you know, in August or whatever. Okay, um, yeah, a lot of people talked about a lot of different like water methods of cooling. Besides, I mean, obviously, the, like, get into an air conditioning built in this, like, the most bulletproof means or whatever, right? But, um, like, people talk about, like, what, like sleeping on intentionally wet sheets, like spraying your, like wearing wet socks, or even damn close when you're trying to sleep. One person was talking about, like, wet the bottom of your curtains and leave the window open so that it like, wicks up the water and then it evaporates. So just basically doing anything that you can to encourage evaporative cooling? Guy Yeah, exactly. Yeah, that's, that's the kind of the biggest thing. Um, and right, it depends on if you're trying to cool yourself or your house, in less energy to cool yourself. Oftentimes, here in the northwest, it's actually more effective to, as soon as the temperature starts climbing in the morning, close all the windows, trap all the cool air from the night in the house and rely on your relation rather than thinking that across breeze from outside 100 degree temperature is going to pull your house. But that only goes so far. And so yeah, there's also the swamp cooler method, which doesn't work in humid places for the same reason. But you can make kind of DIY swamp coolers by putting a wet sheet over a box fan, and then blowing the air through that wet sheet. Okay. Margaret And that kind of answers one of the questions that someone asked, which is like, you know, obviously, whenever bad things happen, only one bad thing happens at a time. But let's say for some weird reason, a bunch of dry heat might cause fire. And, you know, obviously, the West Coast has been blanketed in smoke for the past four years. And like, smoking means you got to keep your window shut. You're saying then you just like basically focus on air movement within the house within with fans and like personal cooling through dehydration? Guy Yeah, yeah, absolutely. To through operation. Yeah, like I would. So when there's when it's not smoke season, which, thankfully is not yet although I think it'll be coming earlier this year, based on our temperatures. When it's not smoke season, I'll open all the windows at night once things cool off, because we do get a big temperature swing here, even in the summer, it cools off at night, and then in the morning, and try to capture some of that cold air during the night variants folk season. Just keep it all closed. Stay inside and focus on that evaporative cooling if you need to. So get yourself wet sit in front of a fan if you don't have electricity, right, people have been keeping themselves cool with fans for 1000s of years before electricity. Big hand fans are really quite effective at moving a lot of air quickly. Without much exertion. Margaret Okay, so the trade off would be worth it of the exertion of physical motion for the like evaporative cooling? Yeah, Guy absolutely. Yeah, it doesn't take that much work to fan yourself out a fan a friend, as long as you're able to get yourself wet, right? If you're just being hot air across yourself. That's not going to do any good. Margaret does that tie into the one of the questions I got that I just you know, it's like a piece of information that people have that I don't know, one way or another. I've never heard of it before someone asked if fanning is bad and extreme heat, how do you pull yourself off? It's probably only saying it's like you're suggesting it's probably only hot, bad if the if you're not causing evaporative cooling? And if you're not, if there's no water on you. Exactly. Yeah. Guy And I looked that one up because I had actually never heard that before. And it actually is I think it's a CDC. It's some government guideline. I think it's from the CDC. And it's just really, this this example of policies and advice being written in a way that's totally robbed of context and is more confusing to people than not, which often is the case if you're just moving hot air across Someone, that definitely will be worse because air there's some amount of convection, right. But we also create a little bubble around ourselves. And this happens all the time a little bubble of temperature of air, close to our skin that's close to our skin temperature. And so it will be slightly more than 108 degrees outside, if we're effectively sweating and evaporating some, it'll be slightly warmer in cold temperatures. And if that air is not being disturbed, then then it'll help us thermoregulate just a little bit. And if we're moving really hot air across that, then that'll heat us up faster in the same way that sticking your hand or your foot in an ice cream or moving water, you're gonna get a lot colder than sticking that foot in the same temperature water that's not moving. build up a little insulated layer. But that only but but you just fix the problem by adding water. And then it's not a problem anymore, because evaporation is much more powerful at cooling. Okay, yeah. Margaret So if people don't have much access to water, basically it's like, get access to water. If you can't get access to air conditioning, you just need access to water is that kind of? Yeah, pretty big deal. Guy I think that's the big thing. And so it's certainly we should have water to drink maintain good hydration but having water that you can use to cool yourself down and whether that's a stream or a river or a lake or whether that's just carrying some extra water with you know that you don't need it to drink so you can use it to what your clothes down. Margaret And would Gatorade be more effective for this? Like it has electrolytes in it. And I know electrolytes are good when it's hot out. Um, for cooling yourself down. Yeah. No, no, no interesting way. The only good thing Gatorade is for Yeah, lots of sugar. You're gonna fuck up my chance for a sponsorship. Guy That Gatorade actually got us into this whole bind with hyponatremia because they sponsored sports medicine conferences from the neighborhood 1000s. And all the studies came out saying how important hydration was and we realized that people are dying all over the place because they're drinking too much. Get rid of too much. Margaret Oh my god, it's literally the plot of idiocracy. Great, cool that that makes me feel really good about the world. Fuck. Okay. Oh, do you know much about like, dealing with pets? Like, I guess Like what? Like most? Most animals don't sweat? Are we the only animals that sweat? Like, what's the deal with keeping pets? Cool? Guy Yeah, I don't know as much about pets, dogs, dogs sweat, but only through their feet. Do sweat. So um, but they just don't, right? They're mostly covered in hair. So they're not going to as effectively be able to cool themselves down. Cats are the same. I don't know about other animals. But right, you're not gonna sweat if you're covered in here because it won't be effective at all. Okay, and so for pets, it's really helped me and a lot of it is the same. Stay inside, stay in cool, shady areas, right? Get some damp clothes or damp bandana or something on them. We could like wet down a sheet or add like a dog. Just get it damp. And put that on the floor for them to sleep on. I've heard of people putting in a couple ice cubes in water bowls. I don't know whether that is actually effective at cooling your dog down but they probably like it. And then and then avoiding exertion the same way. Yeah. Margaret Okay. Well and okay with the cold water and maybe it doesn't help but it it tastes better to them or something like that. People have questions. I have questions. I don't know enough about this. Like it, it seems like would be drinking like ice cold water, kind of shock your system. Like if you're even if like someone has heat exhaustion or god forbid heatstroke and you don't have access to the hospital. But whatever is it like, Is there an ideal temperature? Do you only want it a little bit colder than their body? Or is it like? No, we would if I can put them on glacier if you could? Guy Yeah, absolutely. The the big problem with heatstroke is someone's brain is cooking. And so we want to stop the cooking as quickly as possible. And we do that by putting them in cold water. And there's just not much evidence but putting someone in cold water from from an overheated position does any kind of damage to them. We're not going to make someone hypothermic with 30 minutes in cold water when they've been overheated. We're not gonna we're Yeah, they might gasp and a little bit and we get that cold water on our skin. We have an involuntary gasp reflex and then we adjust to the water temperature, but it's not going to do any damage. And same with drinking ice water. The temperature of the water doesn't make a huge difference in changing the temperature of our bodies. But it's not like drinking water will cool us faster than drinking warm water. But I know that I'm more likely to drink water when it's hot out if the water is cold and refreshing, and so, right. So the way to stay adequately hydrated. ice water is great. You can stick around your forehead and call yourself down. Margaret Yeah, okay, so they said like, like sticky. So like getting the ice water on you is probably more important than getting ice water in you in terms of Guy Yeah, if you only have enough. Yeah, but I mean, I just, you know, you get that big glass of ice water and it's condensing on the outside and outside is super cold, huh? Yeah. Okay, hold on to it, and stick that jar on your forehead until you till you drink it. Okay. Margaret So I'm not gonna get the story about dehydration out of him. Guy Uh, well, I'm trying to think of what our friend would be talking about. The the story that I do have is, and this is this is just more of a general warning story about tunnel vision. And people who are convinced that they're right about something, and they don't look at all the facts. But I was several years ago, I was guiding in the Grand Canyon. And I ran into ran into a couple of people who were in fairly substantial distress. And they were a day behind their schedule, they'd gone about four miles, maybe five miles in about 24 hours. And they were convinced that there was only one person who is really having trouble. And he was nauseous, he didn't feel good, little unsteady on his feet, really classic, pale kind of pale, clammy skin, really classic heat exhaustion symptoms. And his friend who claims to be a guide, with him was convinced of the altitude illness, because he was nauseous and had a headache. And because the Rim of the Grand Canyon was 7000 feet, which is not actually very high. Altitude illness goes. But they were convinced that they had altitude on this. And so they were descending into the canyon where it got hotter. And the only solution they thought was to keep going down, because if they dropped an elevation, then they'd fix the altitude and less problem. And so I tried to talk to them, and convince them that I wasn't altitude illness, and that, in fact, it was extremely hot. And they weren't a climatized to the heat, because it was springtime. And they had just come from the Midwest where it was 40 degrees outside and I was 100 degrees in the canyon. And they wouldn't listen to me. And I ended up running into a couple paramedics on the trail, who were hiking behind me and caught up and overtook me. And they had also encountered this person after I did stop them did a full assessment, knew it was heat exhaustion, tried to convince the people to stop and rest and turn around. Or they weren't having any of it. They were convinced that it was altitude LS ran into a ranger later on, who also tried to convince him to turn around. And I don't know what happened to them. He clearly didn't die, because I would have heard about a death in the canyon, but certainly didn't have a good time. And I think the big takeaway there is we as humans, I think as soon as we think we've identified what a problem is, then we start trying to solve it. And then we ignore all of the other evidence that suggests that could be a different problem. And so I think, anytime that you're feeling bad or your friend is feeling bad, or they're feeling sick, and you think you know what's going on, it's worth stopping and asking yourselves, especially if they're not getting any better. Mm hmm. Is it actually this thing? Is it actually dehydration? Maybe it's hyponatremia I should stop giving this person a water? Margaret Yeah. Guy Is it actually altitude illness, or maybe it's really hot out and you feel crappy, and you should be in the shade and lie down and rest and fan you until you feel better? Instead of trying to rush down to drop in elevation? And yeah. Margaret If you had a whole group of people in five people, and they're all exposed to the exact same, you know, you're all hiking together roughly the same amount of exertion etc. Is everyone gonna get heatstroke at the same time? Or is it like fairly personal about that? Guy there's a there's a pretty wide range in human tolerance for heat and exertion. So yeah, it can be all over the place. I would say that the right the hotter it gets, the higher the probability of heat exhaustion or heat stroke here. But but it's like human bodies are really amazing when they're really adaptable and right we think of 105 degree internal temperature, like you stick a thermometer in someone's mouth. When they read the 105, we say medicine says that heat stroke their brains. But there are also some ultra marathon athletes who run in really hot weather who have recorded internal temps of 105. And they're totally fine. Okay, and that's probably because they've acclimated to that over a long time. And we've actually been able to change their physiology and what their bodies do. So people, people have really different responses. And so we should be looking at how are people doing and asking our friends and looking for these these little telltale signs? Oh, yeah, this person's a little grumpier than usual. And kind of ornery, and they look a little pale, and they're kind of slower to respond, we should check in how are you doing? How are you feeling? Rather than thinking that the objective conditions are what's going to dictate? When? Margaret Yeah, okay. Yeah. And that kind of answers or starts to answer one of the questions that a couple people asked, which is like, basically, what do you do if you're someone who just hates heat? Right? Like, I definitely have friends who like they, you know, I'm always I don't hate heat the same way. I hate being cold. You know? You think that's like, just like a lifetime acclamation and like, basically, the answer is slowly acclimate climatized rather than suddenly have a what's it called, like a heat Hill, a heat bulb? on some horrible name for what's happening to you all? Yeah. Guy Don't have the bad thing happen is that is that as a heat dome, they keep inventing new names for weather phenomenon that have actually been around forever. You know, I'm not that this particular heat wave has been around forever. It's certainly new. But I just think about the like, Arctic bomb polar vortex. New now that we're finally all paying attention to the weather. Yeah. All these new terms about it instead of I don't know, stopping emitting carbon and planting a lot of trees. B time. That'd be a lot of work. Yeah, it'd be a lot of work. It's a lot a lot easier to name all the problems and make some ad revenue off of driving clicks to website. But I digress. Yeah, some people don't like heat. I think that as a person who doesn't like heat, and who also guided in the desert, for many years, I think the climate Ising makes a big difference. And slowly, right, go to a new environment, if you're not being confronted by one of these heat waves, you go to a different environment, and you don't do your normal level exertion of exertion. You just dressed and you're hanging out and you expose yourself to the temperature, and then you go and you cool off and do it again. And then you do it again. And you'll become more used to that, and especially if you're using other techniques to keep yourself cool. It's interesting. I think that I get grumpier with heat here in the Pacific Northwest than I ever did when I was guiding in the desert. And I think it was, I think a lot of it was the climate tising. And, and having an orientation of I know, I'm in a hot place here. And so I need to change my behavior. And I need to change how I'm managing my body so that I can stay cool. Whereas it gets hot right here. And I think I should just be able to do all the things I can normally do. And now I feel terrible. And I'm mad. Just because I'm too hot. Margaret Yeah. So it's like, maybe maybe part of the whole answer is like actually change your pattern of behavior. Which actually ties into both the we're all gonna die because of global warming, if we don't do anything, and then also the, like, what you talked about, about the person who is, you know, walking further and further down, because they were like, No, no, no, no, it's it's climate sickness, you know, or whatever, or not climbing, altitude sickness. And then like, I know that when I want to do cognitive behavioral therapy, like the thing that we have to throw away first is I tell, I tell the therapist, what's wrong. And then therapist, it's like, able to specifically say, Now I know what isn't wrong. Like, that's your narrative. That's the thing that you like have been telling yourself. Yeah. And clearly telling yourself this didn't work so and, yeah, which we need to do as a society we need to actually change our patterns in the same way that y'all in the Pacific Northwest should avoid exertion and as you suggested, the very beginning And then work with your co workers to collectively avoid exertion, you know? Yeah. Yeah. Just easier said than done from someone who's a remote worker on the East Coast but okay. Oh, sorry, is one more people talk about? Like one question left food drug medications to avoid our caffeine and alcohol like absolutely terrible anathema if you take, like, different, you know, different medications is going to impact the degree to which you're sensitive, and are the things that people can do about that. Guy Yeah, um, there's certainly some risk factors. In general, caffeine and alcohol both just don't help the body adapt to any kind of changing environment. And so cold, hot altitude, all of these things, caffeine and alcohol aren't going to make us feel better. And whether that's a huge risk factor. I'm not convinced. I'm still gonna drink my coffee in the morning, but I'll probably make a cold brew. And, but I'm not going to drink coffee all day, and I'm not going to sit in the sun drinking beer all day. Some other some other medications, some allergy medications, and decongestants have some linkage to just reducing the body's ability to thermo regulate and to cool down. Now, I'm definitely not a doctor. And so if people are taking medication they should, they should look at that medication specifically and look it up and just Google that medication and heat exhaustion or heatstroke and see what see if there's a contraindication or or an extra risk factor there. We'll probably get better, better information from that than from broad and general statements from the way that this Margaret podcast is this past guest is your doc is not just your doctor, but everyone is listening. Yes, we are both doctors. I thought that was the basis of okay. Okay, um, make sense? Do you have any, like, final thoughts like things about like, laying, you know, how are you feeling about this whole thing? Or, you know, things that we missed talking about all of this? Guy Yeah, no, I really enjoyed this conversation. I think we hit like, we had a lot of topics, I can kind of nerd out about physiology and bodies and illnesses for a while. So it's been fun to do this with heat. I'm going to make a weird plug, which is, I really believe in umbrellas in the summer first. So like, silver reflective or light colored umbrellas, just thinking of other prevention techniques of carry your portable shade with you and thinking particularly about houseless people who can't access cool areas, get a cheap, bright colored umbrella, and you've got your own shade, and it'll help. So I just wanted to throw that one in there. I hiked with an umbrella in the Grand Canyon all the time. Margaret And so I'm really excited about that. Yeah, he said bright colored. But you know what? Yeah, Guy mine was silver. It was nice and reflective, really any anything that will reflect rather than absorb heat? Margaret Could you tape an emergency blanket to on or something? Guy Yeah, sure. Absolutely. Yeah. And then and then beyond that, I just think that it's going to be hot here this week. People up here are, I think, probably simultaneously freaking out more than they need to and not enough. By which I mean, a couple of days of extreme heat are going to be challenging for people and we should take care of each other and look out for marginalized and vulnerable people are probably not going to see a lot of deaths. Huge, huge problems with a short heatwave like this. However, we should be freaking out about the fact that it's 108 degrees in the Pacific Northwest in June. And this is really like where we are headed as a planet. And so we need to be thinking and adapting right now and thinking about how can we, first of all right, stop emitting carbon and lock as much carbon as possible in the ground. And second of all, how can we change our environments and our behaviors to live in a hotter world and working? Yeah. Working 40 hours a week in an urban concrete. Metropolis is not going to be tenable couple decades from now, when? Right? Think about the thing about Texas right and last summer, they got that big cold wave and then the last Electricity and we have all these deaths because people could no longer to heat their homes and we're gonna see the same thing with with heat waves as well, where we have brownouts and blackouts, because there's too much electrical demand while the air conditioners running. And so we need to be thinking about how can we keep ourselves cool without relying on air conditioning? How can we change our behaviors and our patterns to do that? And how can we plant a shit ton of trees? Yeah, because really, not not only because because they fixed carbon. But because trees cool the environment down the local environment. They, right. evaporation is a major cooling effect. And trees of apo transport transpire huge amounts of moisture, when they're photosynthesizing. And all that moisture cools an area down. And so how can we convert these giant, awful concrete metropolises into beautiful forest gardens, we can survive and have food to eat. And also so that we can cool the areas where people are concentrated down. When we write we see this with just disparities in in heat related deaths across the country where people who are lower income or marginalized or of color live in areas that are more paid to have less access to green space, and they get hotter, and they're more exposed to environmental extremes. So yeah, we should we should take care of each other in the coming week. And stay cool. And we should plant a lot of trees and stop trying to pretend we can continue living as normal. When it's not normal anymore. I like that because Margaret it it covers it you know, most This podcast is about what most of this episode has been about, like what to do in the very immediate short term, right have to solve this problem, or make it through this problem. But the solutions like absolutely have to be long term and ongoing. And I like that you tied that into that. Um, do you have Do you have anything that you want to like shout out like any any thing you want to plug any? I don't I don't know whether your medic trainings are public or if people want to like follow you. Do you do social media stuff? Anything? Guy No, not right. I'm pretty. We're pretty non existent on the internet. No, social media. But yeah, we do. We do street medic trainings on and off in the Pacific Northwest, you haven't done one in a while. Hopefully will again, I will plug actually because I am in the process of moving up all the way to the peninsula. And there's a there's an amazing new community project forming in quilcene. people bought an old theater there a couple of years ago, the gray coast Guild Hall. There, they're just starting some big fundraising campaigns right now to replace the roof and do a bunch of infrastructure upgrades so that it can be a community gathering space and a resource and hopefully a place that people who are all thinking about how do we how do we actually live together throughout this climate changing world in the long term? Can I encounter each other and so a great coast Guild Hall could definitely use some dollars with you Google that or look it up they have a Patreon. I don't know if they've launched their big Kickstarter fundraiser yet. But yeah, Margaret yeah, and one of the reasons I'm excited about that project is because it's you know, it's a, it's a social center will be a social center, and it's like, collectively operated, and it's within a pretty small town. And so it's a pretty major percent of that town's like, social and cultural, like, life or something like that. And it kind of really interesting way. Yeah, so it's, I agree, it's absolutely worth supporting. Normally, I do this whole, like separate outro but and so I'm gonna make you stay on the call as I do my outro. So that way, all of my files are in place, so I can edit this as quickly as possible. But thanks, everyone, for listening. And if you want to support this podcast, you can do so by supporting currently me on patreon at patreon.com/margaretkilljoy. But in the very near future, that same Patreon will switch over, you won't have to do anything on your end to support a larger collective effort that's going to be doing more podcasts and more zine publishing, called strangers in a tangled wilderness. And I'm very excited about moving to a more collective structure. It makes just you know, the many hands make light work as long as many hands and make everyone crouching getting each other's way. And in particular, and also you can tell people about the podcast and that's the main way and you can, you can thank us by telling people about it. But in particular, I want to thank Sean and Hugh and Dana and Chelsea Eleanor Mike staro, Kat j, the compound, Shane, Christopher, Sam, Natalie, Willow, Kirk, Hoss the Dog, Nora, and Chris, for making this possible. And, yeah, thanks so much. And I hope everyone is doing as well as they can with everything that happens and stay safe. And it seems like maybe one of the main messages about this is that well, yeah, like Guy already said it. You don't have to freak out as bad about this one specific thing, but we need to freak out more about the larger, larger things. Find out more at https://live-like-the-world-is-dying.pinecast.co
The hymn I Sing a Son of the Saints of God says,"You can meet them in school, or in lanes, or at sea, in church, or in trains, or in shops, or at tea; for the saints of God are just folk like me, and I mean to be one too."But...what makes someone a saint? This episode tells the story of a mentor of mine who exhibited what I believe to be an essential trait of anyone who is trying to live a holy or saint-like life. Have a spiritual, theological, or religious question you would like me to tackle?Contact me via email: Dan@skypilot.zoneAnd be sure to check me out on Facebook: https://www.facebook.com/SkyPilotFaithQuest...........................................................................................Music: Composed for SkyPilot: Faith Quest by Arlan Sunnarborg
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Antoine Georges Physique de la matière condensée Année 2020-2021 Le modèle de Hubbard fermionique : introduction et progrès récents Paradigme de la physique des systèmes quantiques en interaction, le modèle de Hubbard a dans ce domaine un statut similaire à celui du modèle d’Ising en physique statistique. C’est le modèle le plus simple à formuler, mais dont on peut espérer qu’il suffise à comprendre au moins qualitativement certains phénomènes collectifs comme le magnétisme, les transitions métal-isolant ou la supraconductivité non-conventionnelle. Malgré sa simplicité, ce modèle constitue un formidable défi théorique. Après une introduction aux motivations physiques – depuis les matériaux à fortes corrélations électroniques jusqu’aux atomes froids dans les réseaux optiques – le cours de cette année fera le point sur l’état actuel de notre compréhension de ce modèle, particulièrement en deux dimensions, et présentera les principales méthodes ayant permis des progrès récents ou laissant espérer des avancées prochaines.
Being fierce isn't always loud. It isn't always logical. It isn't always easy. Join Jennifer Lasik as she explores what it means to be fierce as a Christian, and how Christians can avoid the pitfalls of “Stockholm Syndrome” and getting stuck in the midst of heavy loss. “I Sing the Song of Fierce” — and you can, too. Jennifer Lasik is a Christian teacher and consultant who believes that the power of love and redemption found in Jesus Christ is the only thing strong enough to heal our communities, our country and our world.
We are recording our in-person worship service (10:45 AM on Sunday) each week for folks who can't join us in person. This is the Audio-only version recorded for Sunday, April 11, 2021. It is also available in Video format through our YouTube channel. Click on the "Notes Icon" (the little image of a notepad) to get the sermon study notes for this week. ORDER OF SERVICE: Sing our opening songs, "I Sing the Mighty Power of God” and “How Deep the Father's Love for Us" (on-screen lyrics in the video recording). Listen to the message "The Final Harvest” preached by Pastor Dave Marksbury from Revelation 14:14-20. This message is part of the multi-week sermon series "Revelation: God's Final Call." (Prior messages in the series are available in both video and audio-only recordings). Sing: "Trust and Obey" and "In Christ Alone.” Then hear special music, “There is a Fountain.” Join us in prayer, listen to the church announcements and a "One Year Bible Reading" update. Our closing song is "He Keeps Me Singing."
A reading of Walt Whitman's poem "I Sing the Body Electric." The reading is from the earliest published version of the poem, in the 1855 edition of Leaves of Grass, where the poems was untitled. The full text of that version is here; the final revision of the poem is here. The best place to find Whitman's poetry online (or anything about him at all) remains the Whitman Archive, and you can find every edition of Leaves of Grass here (as plain text downloads) and here (facsimiles of the original editions). While there are hundreds of editions of Whitman's poetry in print, the best editions for me are Gary Schmidgall's Walt Whitman: Selected Poems 1855-1892, which present his best poems in their earliest published form (this is the book I am reading from here); the second includes the first and last editions of Leaves of Grass, along with a huge selection of Whitman's prose. Any comments, or suggestions for readings I should make in later episodes, can be emailed to humanvoiceswakeus1@gmail.com. I assume that the small amount of work presented in each episode constitutes fair use. Publishers, authors, or other copyright holders who would prefer to not have their work presented here can also email me at humanvoiceswakeus1@gmail.com, and I will remove the episode immediately.
Sermons-First Unitarian Universalist Society of San Francisco
“I Sing the Body Electric" (November 22, 2020) Worship Service There is so much to give thanks for, but what about this body that carries us through the world; the ones poets and scientists, photographers and even the Psalmists could not help but be astounded by. So, a little tribute to the gorgeous miracle and mystery and work of art -- the human body. Rev. Vanessa Rush Southern, Senior Minister Mari Magaloni, Reflection Reiko Oda Lane, organist Mark Sumner, director/piano Leandra Ramm, soprano Brielle Marina Neilson, alto Ben Rudiak-Gould, tenor Asher Davison, bass My-Hoa Steger, pianist Eric Shackelford, camera Shulee Ong, camera Joe Chapot, Social Media Chat Support Alex Darr, Coffee Hour Zoom Jonathan Silk, OOS, Sound, drums Order of Service: https://content.uusf.org/Order_Of_Service/2020/20201122OSWeb.pdf All Music: https://content.uusf.org/Sound/20201122Music.mp3 Reflecton: https://content.uusf.org/Sound/Reflections/202011122MMReflection.mp3
Sermons-First Unitarian Universalist Society of San Francisco
“I Sing the Body Electric" (November 22, 2020) Worship Service There is so much to give thanks for, but what about this body that carries us through the world; the ones poets and scientists, photographers and even the Psalmists could not help but be astounded by. So, a little tribute to the gorgeous miracle and mystery and work of art -- the human body. Rev. Vanessa Rush Southern, Senior Minister Mari Magaloni, Reflection Reiko Oda Lane, organist Mark Sumner, director/piano Leandra Ramm, soprano Brielle Marina Neilson, alto Ben Rudiak-Gould, tenor Asher Davison, bass My-Hoa Steger, pianist Eric Shackelford, camera Shulee Ong, camera Joe Chapot, Social Media Chat Support Alex Darr, Coffee Hour Zoom Jonathan Silk, OOS, Sound, drums Order of Service: https://content.uusf.org/Order_Of_Service/2020/20201122OSWeb.pdf All Music: https://content.uusf.org/Sound/20201122Music.mp3 Reflecton: https://content.uusf.org/Sound/Reflections/202011122MMReflection.mp3
Complete Service-First Unitarian Universalist Society of San Francisco
“I Sing the Body Electric" (November 22, 2020) Worship Service There is so much to give thanks for, but what about this body that carries us through the world; the ones poets and scientists, photographers and even the Psalmists could not help but be astounded by. So, a little tribute to the gorgeous miracle and mystery and work of art -- the human body. Rev. Vanessa Rush Southern, Senior Minister Mari Magaloni, Reflection Reiko Oda Lane, organist Mark Sumner, director/piano Leandra Ramm, soprano Brielle Marina Neilson, alto Ben Rudiak-Gould, tenor Asher Davison, bass My-Hoa Steger, pianist Eric Shackelford, camera Shulee Ong, camera Joe Chapot, Social Media Chat Support Alex Darr, Coffee Hour Zoom Jonathan Silk, OOS, Sound, drums Order of Service: https://content.uusf.org/Order_Of_Service/2020/20201122OSWeb.pdf All Music: https://content.uusf.org/Sound/20201122Music.mp3 Reflecton: https://content.uusf.org/Sound/Reflections/202011122MMReflection.mp3
Thanks for praying and worshiping with me today. As always, our Scripture readings and general order come from the Book of Common Prayer (1979) Daily Office. In the Church calendar, it is Ordinary Time, Proper 27. We’ll begin with a sung version of the opening sentences. After a prayer of confession, we’ll read from Psalm 70 followed by the Gloria Patri. Our Lesson is Amos 5:18-24. After the Apostles’ Creed, the Lord’s Prayer, and the Collect of the Day, we’ll sing, “Bravely, I Sing” by me. Then we’ll enter a time of guided prayer. Photograph by me If you have a prayer request please submit it at http://benwardmusic.com/prayerrequest. If you’d like to be on the email list visit http://benwardmusic.com/email. Visit https://patreon.com/morningprayer to give and support Morning Prayer!
Our first music episode of the AscensionNYC podcast! This episode features the hymns and anthems recorded by Dr. Dennis Keene and the Ascension Choir, featuring the Manton Memorial Organ, for the Church of the Ascension's All Saints Day service, November 1, 2020, which took place online via Zoom. All Saints Day MP3jPLAYLISTS.inline_14 = [ { name: "All Saints Day", formats: ["mp3"], mp3: "aHR0cHM6Ly9hc2NlbnNpb25ueWMub3JnL3dwc3lzdGVtL3dwLWNvbnRlbnQvdXBsb2Fkcy8yMDIwLzExL0FsbC1TYWludHMtRGF5LTIwMjAtQXNjZW5zaW9uLUNob2lyLm1wMw==", counterpart:"", artist: "", image: "", imgurl: "" } ]; MP3jPLAYERS[14] = { list: MP3jPLAYLISTS.inline_14, tr:0, type:'single', lstate:'', loop:false, play_txt:' ', pause_txt:' ', pp_title:'', autoplay:false, download:false, vol:100, height:'' }; Hymn #287: For All the Saints, Who From Their Labors Rest (Sine Nomine) Let us Now Praise Famous Men, by Ralph Vaughan Williams (1872-1958) The Beatitudes (Russian Orthodox Chant) Hymn #293: I Sing a Song of the Saints of God (Grand Isle)
From a Tokyo street parade advertising the services of a shady prosperity church to the global pandemic, with pit stops in pain, death, suffering, and theodicy, this episode is sure to be a real crowd pleaser. Also, why you should go to the emergency room for a broken bone or infected wound but try Jesus for chronic conditions, death being the most chronic condition of all. Support us on Patreon! Notes: 1. Here's a short article I wrote on the International Lutheran-Pentecostal dialogue's meeting in Madagascar in 2019, where we discussed the topic of healing and deliverance. God willing and the creek don't rise, the final report will be released in 2021. You may also like the chapter on "Prosperity" in my book A Guide to Pentecostal Movements for Lutherans 2. A whole slew of OT studies by Claus Westermann 3. Becker, The Denial of Death 4. The first of Luther's 95 Theses issues a call to lifelong repentance 5. Dad takes up the theme of "purgatory now!" in Luther vs. Pope Leo 6. On the Blumhardts, father and son, see respectively Ising's Johann Christoph Blumhardt: Life and Work and Zahl's Pneumatology and Theology of the Cross in the Preaching of Christoph Friedrich Blumhardt 7. Not a whole lot on Nenilava just yet, but I'm working on it—look for the first-ever full-length work on her next year. Meanwhile, check out the entry on the fabulous online Dictionary of African Christian Biography. 8. Dad refers to the "service of the word for healing" in the Lutheran Book of Worship—it's actually in the companion to that hymnal, called Occasional Services More about us at sarahhinlickywilson.com and paulhinlicky.com!
We have resumed our in-person worship service (10:45 AM on Sunday) and are recording them each week for folks who can't join us in person. This is the Audio-only version recorded for Sunday, September 27, 2020. It is also available in Video format through our YouTube channel. Click on the "Notes Icon" (the little image of a notepad) to get the Special Edition Study Guide that includes “God's Prophetic Time Line” and “Daniel's 70 Weeks.” ORDER OF SERVICE: Sing along with our opening songs, "I Sing the Mighty Power of God” and “Wonderful, Merciful Savior" (on-screen lyrics in the video recording). Listen to Part 2 of the message "The Key to Understanding Prophecy” preached by Pastor Dave Marksbury. (Part 1 was preached on September 20th). This message is part of the multi-week sermon series "Revelation: God's Final Call." (Prior messages in the series are available in both video and audio-only recordings). Sing along with our worship team: "One Day" and "In Times Like These.” Join us in prayer, listen to the church announcements and a "One Year Bible Reading" update. Our closing song is "Because He Lives."
Poddavsnitt med Helena Rydh, sångerska, sångpedagog och körledare inom jazz, pop, soul, gospel mm. Bland annat är hon konstnärlig ledare för proffskören One Voice. Hon är också en av sångpedagogerna bakom "iSing- din sångtränare på nätet". Vi pratar om sång, om att träna rösten och mycket mycket annat.
“Let There Be,” the 8/9/2020 sermon (from the peak of Raspberry Mountain in Colorado!) by Pastor Matt Sturtevant, and the 2nd sermon in the A Season of Creation worship series. (The 1st sermon in the series was at Car Church in the parking lot on Sat. 8/8.) Podcast includes entire worship service. Music licensing: The following music was used with permission under CCLI streaming license #20126570. “Let the Earth Rejoice!” Dale Wood © 1996 The Sacred Music Press “I Sing the Mighty Power of God” Tune: FOREST GREEN Ralph Vaughan Williams (1906) Text: Isaac Watts (1715) Public domain. “Creation Sings” Tune & Text: CREATION SINGS, by Keith Getty, Stuart Towend, & Kristyn Getty (2008). ©2008 ThankYou Music (Admin. by EMI CMG Publishing) “How Great Thou Art” Tune: HOW GREAT THOU ART. Tune & text by Stuart K. Hine. Tune, 1948; text, 1953. ©1953 S. K. Hine. Ren. 1981. Administrator: Manna Music, Inc. “Let My Words Be Few” Matt and Beth Redman/Arr. Phillip Keveren ©2002, Kingsway’s ThankYou Music. “God Has Given Us Creation” Tune: JUBILEE. Harm. by Donald Murphy (2008). Harm. © 2010 Celebrating Grace, Inc. Text: David W. Music (1997). ©1998 Broadman Press. “Praise, My Soul, the King of Heaven” Lani Smith (Lauda Anima by John Goss) ©1975, Lorenz Publishing Co.
Morgan Millogo graduated with a BFA in Film and Television Production from NYU's Tisch School of the Arts. A Washington native, Morgan spent five years as part of the Seattle Indy film scene as an actor and director and was also a Burlesque Performer and Emcee. After the unexpected death of her father, Morgan lived as a nomad and became a Certified Contemporary Shamanic Practitioner and Yogi. Now relocated to the Hudson Valley, Morgan most recently worked as Head of Production at InsideRisk LLC and part of the core content team, overseeing the development of an interactive television series as well as live multi-media events throughout the world focused on fostering critical thinking. Her recently released web series, TABS AND CLEA, marks her first project as a writer, actor, director and producer since the passing of her father in 2010. Meg Affonso is an intuitive artist, actor, choreographer, writer, producer & director; she is a gifted storyteller who has the performing arts ingrained in her soul. Meg has performed in a variety of theatrical productions, ranging from musical theatre to dramatic plays. Meg has studied various forms of dance throughout her life and has performed in film, web series productions, commercials & television. Meg has written two screenplays & a stage play and continues to be open to art in all of its forms. Meg's mission is to tell stories that matter & to help others by introducing them to art as a multifaceted healing modality. She is one of the cast of Tabs & Clea and has an upcoming performance show titled, BODY, happening at the Albany Center Gallery the next three consecutive Sundays. Morgan directed the short film which will be a part of the performance.Tabs & Clea: Tabs, a psychic who has dedicated her life to helping people, has fallen into a crisis of faith. When her audacious ex-roommate, Clea, unexpectedly shows up and demands to know why Tabs has stopped using her gift, Tabs is forced to face and discover the truth of a tragedy she did not foresee.BODY: Sundays, August 2, 9, & 16, from 2:00 - 4:00 p.m. -- Meg Affonso and Albany Center Gallery present BODY, an experiential and immersive art installation that explores the sacred connection between the body and the soul that exists in each individual. The public is invited to attend free of charge (ages 12 & up, content not suitable for small children). Signing up in advance is recommended to reserve a spot, but walk-ins are accepted if there is available room. Do so here: http://www.eventbrite.com/e/body-tickets-112398521002 Shows are filling up!The elements of BODY include: three short dance/dialogue-based films, live sculpture + movement, an immersive audience experience, collective artistic creation, photography, and movement labs and release through writing that will be transformed into physical art that represents rebirth. BODY is inspired by the poem “I Sing the Body Electric” by Walt Whitman and also by the current events in today's world. BODY is representative of the struggles that individuals face from birth through death and the beauty that exists in between all of the difficulties. BODY is an examination of our ego, prejudices, biases and the truth of what we can be if we choose to grow and live our soul's truth. This piece is a collective experience for the community not just by telling a story, but also by encouraging art as a path to the healing and joy that we can all experience no matter our backgrounds or beliefs.Today we talk about being storytellers, relationships, their work, ego and women in TV and film. Lots of fun, lots of laughs too!And here's the previous show with Maria we mentioned!Today's show was engineered Nick Panken host of Freedom Highway from radiokingston.orgWe also heard music from Shana Falana!Feel free to email me, say hello: she@iwantwhatshehas.orgLeave me a voicemail with your thoughts or a few words about who has what you want and why! (845) 481-3429** Please: SUBSCRIBE to the pod and leave a REVIEW wherever you are listening, it helps other users FIND IThttp://iwantwhatshehas.org/podcastITUNES | SPOTIFY | STITCHERITUNES: https://itunes.apple.com/us/podcast/i-want-what-she-has/id1451648361?mt=2SPOTIFY:https://open.spotify.com/show/77pmJwS2q9vTywz7Uhiyff?si=G2eYCjLjT3KltgdfA6XXCASTITCHER: https://www.stitcher.com/podcast/she-wants/i-want-what-she-has?refid=stpr'Follow:INSTAGRAM * https://www.instagram.com/iwantwhatshehaspodcast/FACEBOOK * https://www.facebook.com/iwantwhatshehaspodcastTWITTER * https://twitter.com/wantwhatshehas
Jonathan Burke, originally from Baltimore, MD, began his acting training in high school at the Baltimore School for the Arts, and ultimately received a BFA from Ithaca College. He was most recently seen on Broadway as Young Man 5/Toby’s Agent/Charles Wilcox in The Inheritance. He also appeared as the leading role, Pharus Jonathan Young, in the Broadway premiere of Choir Boy and was a member of the Original Broadway Cast of Tuck Everlasting. Jonathan was seen Off-Broadway as Elzie in Toni Stone at the Roundabout Theatre Company’s Laura Pels Theatre, as Priest/Judge in Joan of Arc: Into the Fire at the Public Theater, and as Junior Addict in Langston in Harlem at Urban Stages. His tour credits include Mary Poppins, A Christmas Story: The Musical, Joseph..., and Cats, in which he played Mungojerrie. Regionally, he has appeared as Crier in Head of Passes at Berkeley Rep, Tyler in Amazing Grace at Goodspeed, Bert in Mary Poppins at Syracuse Stage, for which he won a SALT Award for Leading Actor in a Musical, Lon Smith in Meet Me In St. Louis at The Muny, David Heard in Choir Boy at the Studio Theatre, Angel in Rent at the Hangar Theatre, Seaweed in Hairspray at the MGR Playhouse, Michael Winans/Howard McCrary in Born For This at the Broad Stage, Granby in I Sing the Rising Sea at the Virginia Stage Company, and Lord High Underling in The Wiz at Baltimore Center Stage. He has also been seen on television in NBC’s medical drama, "New Amsterdam.” Instagram/Twitter: @jondbeee
The Body Electric Yoga Company was founded in 2013. Their mission is to improve the health and happiness of St. Petians by providing accessible, high-quality instruction in supportive, beautiful environments. The studio now serves more than 1,000 clients a week with a staff of 40, welcomes presenters from around the world, and partners with the City, and myriad local businesses and non-profits to bring yoga to the people. The BE is a welcoming community. In their approaches and philosophies we strive to be inclusive, outward-looking, non-intimidating, and non-dogmatic. They believe in the personal and cultural benefits of yoga practices and mindful physical fitness and draw from many modes and lineages. Their goal is to uplift the entire region by improving the well-being of every individual they reach, and to reach as many individuals as possible. "If any thing is sacred the human body is sacred." - Walt Whitman, I Sing the Body Electric, Leaves of Grass, 1855 --- Send in a voice message: https://anchor.fm/thedoctorwhisperer/message
On this episode of mental digestion we explore a fetish Ising. What is it? What are some of the signs and symptoms to look out for? We also give examples and explore ideas surrounding it --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/precious-dockery4/support
The "Inverse Ising Problem" refers to finding the parameters (the Jij's and the hi's) in an Ising model given the first and second moments (the magnetizations mi and the correlation functions cij). This is of considerable interest in machine learning and data analysis whenever the data set and the number of variables is large, but the values taken by the variables can be taken to be "high" and "low". The maximum entropy distributions with given first and second moments then has the Ising form where the hi's and Jij's are Lagrange parameters. Several perturbative methods to solve the inverse Ising problem approximately have been proposed in the last few years. I will give a survey of the situation, with a focus on what we have know about the applicability of these methods to data such as gene expression and recordings from many neurons, where an underlying exact description is surely not of the Ising form. This is work with John Hertz and Yasser Roudi (Frontiers Comp Neuroscience, 2009) and work in progress.
If systems characterized by slow (algebraic) relaxation are prepared in an out-of-equilibrium initial state, one can observe a "physical aging regime" in the ensuing approach to equilibrium that is governed by broken time translation invariance and non-trivial, often universal scaling laws. Dynamical systems near a critical point constitute prototypical and now well-understood examples. Indeed, measuring critical exponents in the intermediate aging rather than the asymptotic stationary temporal regime is now a standard numerical tool. In this talk, I will first apply these concepts to simple driven lattice gases that relax towards non-equilibrium stationary systems displaying generic scale invariance. The expected simple aging behavior in the two-time density auto-correlation function is verified through Monte Carlo simulations in one, two, and three dimensions. Next I shall address the continuous non-equilibrium phase transition in driven Ising lattice gases in two dimensions. Whereas the temporal scaling of the density auto-correlation function in the non-equilibrium steady state does not allow a precise measurement of the associated critical exponents, these can be accurately determined from the aging scaling of the two-time auto-correlations and the order parameter evolution following a quench to the critical point. In the second part of the talk, I will present numerical results for the non-equilibrium relaxation kinetics of interacting magnetic flux lines in disordered type-II superconductors at low temperatures and low magnetic fields, represented by means of a three-dimensional elastic line model. Investigating the vortex density and height auto-correlations as well as the flux line mean-square displacement allows us to carefully disentangle different relaxation mechanisms (e.g., vortex line fluctuations and positional relaxation), and to assess their relative impact on the kinetics of dilute vortex matter at low temperatures. We observe the emergence of genuine glassy dynamics, caused by the competing effects of vortex pinning and long-range repulsive interactions between the flux lines. We contrast the effects of random point-like pinning centers and correlated columnar defects. We also compare data from Monte Carlo simulations with results from Langevin molecular dynamics.
This message was prerecorded by Pastor Dave McAllister of Samish Island Memorial Chapel, to be played on April 26, 2020. Our song of praise for the morning was Isaac Watts's hymn, "I Sing the Mighty Power of God" (https://www.youtube.com/watch?v=9r0_7KxM8E8).
This Sunday morning on ‘The Sinatra Hours’, we celebrate Frank’s covers from the Great American Songbook to Pop Classics from the 40’s through the 80’s. Songs include ‘My Blue Heaven, ‘I Left My Heart in San Francisco’, ‘Mack the Knife’’, ‘I Sing the Songs’, a rare version of ‘Downtown’ featuring daughter Nancy Sinatra (with a […]
Dr. Mohammed is the Founder and President of ManaGene considered one of the most innovative leaders in the emerging personalized medicine and lifestyle genomics space. In August 2018, ManaGene merged with Youtrients (www.youtrients.me) to form a new company known as The DNA Company. The DNA Company represents the evolution of functional genomics and is focused solely on the optimization of human health and performance. Dr. Mohammed is widely regarded as a pioneer in medical genomics and has been the recipient of multiple academic and industry awards. He is the holder of several patents in the general fields of molecular diagnostics and genomics research and is one of the most sought-after national and international conference speakers in the genre of personalized medical genomics. In this interview, Lisa and Dr. Mansoor dive deep into the power that lies in understanding your unique genes to change the outcome of your health. Some take the fatalistic view that if you have a bad gene or combination of genes you are powerless against them so it's best not to know but nothing could be further from the truth. Understanding your genes through DNA testing is like getting the user manual to your body and learning how best to care and treat it. The granularity with which you can start to understand processes and how these affect you and how you impact these is astounding. This s actionable knowledge that will help you make informed decisions regarding your health in such areas as your hormones, your cardiovascular risk factors, your methylation, your detoxification processes and even your mood and behavior, why for example some have a tendency to more problems around depression or PTSD than others. Never before in the history of the human species have we had such deep insides into the way our intricate and complex bodies work. This episode is set to blow your mind and the work of Dr. Mohammed and his team is set to change the future of the world's health. We have the opportunity for the first time to take control of our own destinies rather than falling victim to our genes through a lack of knowledge. Once you start to see and understand the power of functional genomics you won't be able to go back to the way you understood yourself and your body before. Your level of self-acceptance and the ability to help yourself heal and be healthy and whole will be taken to a whole new level. If you would like to get your hormones or your whole genomic profile tested you can find out more at www.thednacompany.com We would like to thank our sponsors for this show: www.vielight.com Makers of Photobiomodulation devices that stimulate the brains mitocondria, the power houses of your brains energy, through infrared light to optimise your brain function. To get 10% off your order use the code: TAMATI at www.vielight.com For Lisa's New Book Relentless visit the website below to order https://shop.lisatamati.com/products/relentless When extreme endurance athlete, Lisa Tamati, was confronted with the hardest challenge of her life, she fought with everything she had. Her beloved mother, Isobel, had suffered a huge aneurysm and stroke and was left with massive brain damage; she was like a baby in a woman's body. The prognosis was dire. There was very little hope that she would ever have any quality of life again. But Lisa is a fighter and stubborn. She absolutely refused to accept the words of the medical fraternity and instead decided that she was going to get her mother back or die trying. For more information on Lisa Tamati's programs, books and documentaries please visit www.lisatamati.com For Lisa's online run training coaching go to https://www.lisatamati.com/page/runningpage/ Join hundreds of athletes from all over the world and all levels smashing their running goals while staying healthy in mind and body. Lisa's Epigenetics Testing Program https://www.lisatamati.com/page/epigenetics/ Get The User Manual For Your Specific Genes Which foods should you eat, and which ones should you avoid? When, and how often should you be eating? What type of exercise does your body respond best to, and when is it best to exercise? Discover the social interactions that will energize you and uncover your natural gifts and talents. These are just some of the questions you'll uncover the answers to in the Lisa Tamati Epigenetics Testing Program along with many others. There's a good reason why epigenetics is being hailed as the "future of personalized health", as it unlocks the user manual you'll wish you'd been born with! No more guesswork. The program, developed by an international team of independent doctors, researchers, and technology programmers for over 15 years, uses a powerful epigenetics analysis platform informed by 100% evidenced-based medical research. The platform uses over 500 algorithms and 10,000 data points per user, to analyze body measurement and lifestyle stress data, that can all be captured from the comfort of your own home For Lisa's Mental Toughness online course visit: https://www.lisatamati.com/page/mindsetuniversity/ Developmental strength, emotional resilience, leadership skills and a never quit mentality - Helping you to reach your full potential and break free of those limiting beliefs. For Lisa's free weekly Podcast "Pushing the Limits" subscribe on iTunes or your favorite podcast app or visit the website https://www.lisatamati.com/page/podcast/ Transcript of the Podcast Speaker 1: (00:01) Welcome to pushing the limits, the show that helps you reach your full potential with your host, Lisa Tamati, brought to you by Lisatamati.com Speaker 2: (00:13) Hey team. We're this week I have an absolutely superstar, the world's number one leading functional genomic specialists, Dr. Mohammed from Toronto and Canada. Dr Mansoor, Mohammed has two guests now. He is a scientist and entrepreneur in the field of genomics and is regarded as one of the most innovative leaders in the emerging personalized medicine and lifestyle genomic space. Dr Mohammed is a PhD and president and scientific officer at the DNA company and is really considered to be a pioneer medical genomics. He's a classically trained molecular immunologist who has received academic and industry awards, published numerous papers and holds patients in the general fields of molecular diagnostics in genomics. Now functional genomics is about understanding the DNA and how it behaves in every definition and this Dr. Mentor was very different than many of the other DNA companies that I've looked at recently and that he doesn't just look at the single litters, if you like, of the DNA, but it looks in combinations of genes. Speaker 2: (01:22) And how they're playing out. And this makes him very, very different. This, he sees DNA like a language rather than a vocabulary and language that has grammar, sentence structure, Syntex and nuances. And you've got to be able to read genetic structure at the holistic level. Now I'm super excited about document's all his work and I'm studying functional genomics at the moment and it is the next level in personalized health. I'm really, really excited to bring this interview to you. It's taken me months to get documents or on this podcast and I'm hoping later on the year to get Dr. Mansoor Down to New Zealand for a lecture tour to speak to functional medicine practitioners down here as well as the public. So if you'd like to know more about that, please reach out to me and let me know. I'm just like to remind you before I hand over to Dr. Mansoor that my book launch is happening just next week over the time of this recording is the 6th of March and on the 11th of March. Speaker 2: (02:26) So by the time this recording actually comes out, my book will be live. It's called relentless and it tells the story of bringing my mum back after a major aneurism myth. You're fighting for a life and lift her in and basically not much over a vegetative state. Massive brain damage at the age of 64 and what I did to beat all the odds and bringing my mum back to health, all of the CRPS I used, the protocols, the attitude, the mindset, the obstacles that we had to overcome, the problems that I've discovered in our medical system in on it goes. So this book is really, I'm, I'm so pleased to be able to bring it out. It's taken me two years to get this together and to bring it to the public, but I really want to pay it forward and I want to help thousands and thousands of other people facing difficult challenges to take them are hit on with the right mindset to overcome great obstacles. Speaker 2: (03:18) So if you'd like to check that out, we can head over to my website. I have Lisatamati.com Hit the shop button and you'll see all of my books there and my jewelry collections. But make sure you check out the neatness. It's really going to be worth a read for anyone who has major medical problems at the moment. Or of course anyone who has a stroke aneurysm Alzheimer's dementia, and wants to know about brain rehabilitation or optimizing your brain function and who isn't interested in that as well as the whole mental attitude and mindset that it takes to do all this. So without further ado, over to Dr. Mansoor Mohammed. Well, hi everybody. Lisa Tamati here at pushing the limits. It's fantastic to have you back again. Now I am just grinning from ear to ear. I can't stop smiling because I've been waiting for this interview for weeks. I have a very, very special guest, Dr. Mansoor Mohammed, all the way from Toronto in Canada. Dr. Mansoor How are you going? Speaker 3: (04:17) I am great, Lisa. And likewise, it's been something that I've been looking forward to, to the audience. Please forgive me. I'm a little bit sleepy from Jeff blog from last night, but Lisa has been pumping me up and so we're going to have some fun of this Speaker 2: (04:31) Now. I know what it's like when you're a little bit jetlagged and you have a main very much in demand. So I'm just so excited to have a little bit of time with you now. Dr Mansoor, I do the whole introduction on a separate recording, but dr Mansoor, can you give us a little bit of background about your what you did your PhD in your, your, a little bit of a brief history of your back. Speaker 3: (04:55) Sure. genes. Genetics has always have always been my love. The study of how this operating manual, just just thinking, just, just dialing it back and thinking that the human being, we've got this operating manual that by every definition of the word it behaves like an operating manual. And to think that it's there and to think that one date might be accessible and that we could read this and we could read it intelligently and just simply understand myself much less, much less. Anyone else has always been my love. And so I started, my PhD is in applied molecular genetics and immunology. So I was looking at the genetics of the immune system. I was very, very fortunate to have an awesome mentor. She was then the chair of molecular biology at UCLA invited me to UCLA. So I had an awesome couple of postdocs there where I got deeper and deeper involved in eugenics. Speaker 3: (05:47) But a real pivotal point happened when I was done, invited to come to Baylor college of medicine and Houston, Texas. And it was that heavy time just about the human genome project, its, you know, sort of pinnacle. And I was asked because of the work that I had been doing with UCLA to come over to Baylor and start a company, the goal of this company was to begin looking at multiplex genomics. In other words, to really do the, you know, the barrage searches into the human genome. Not one gene at a time, but looking at the entire genome in pathway type manners. Now initially we applied this knowledge to cancers. We apply this knowledge to developmental disorders syndromes, Prader, Willi syndrome, autistic spectrum disorders and so on and so forth. And about 15 years ago, after many years of doing what I call disease genomics, looking at the operating manual, looking at when the operating money was broken out of what happens from a disease perspective. Speaker 3: (06:45) Then I sort of thought, okay, well that was fun. That was good. That was, but why should I not look at the operating manual? But nothing is purportedly broken, but just the operating manual. So then still we can tell presumptively healthy individuals how to stay healthy or how to get over the type of chronic illnesses. So this is what I've been doing for the last 15 years, studying, researching and applying the knowledge of the human genomic operating manual. So we've been, we can just simply understand it. How does the body work, which clearly there's an individuality to that, obviously. I mean, we are human beings. We all, our cells, our organs, our bodies, all have to accomplish the same jobs that we do. These jobs with nuance differences, some of us less optimal, more optimal, more efficient, less efficient. And when we can zone into that, when we can read this operating manual from that perspective, really Lisa miracles happened with the sort of insights that you get, the nuances that you can tease out. It really has transformed the clinicians. We train the patients, we work with the transforms, it empowers the individual to understand how their body works and what they might do to obtain that optimal health. Speaker 2: (07:59) This is, and this is a super exciting and I can feel your passion coming through despite the jet lag for this area and it's now mind you, passion is of the last maybe two months or six weeks or however long it is now that I've been diving into this world and just going, Oh my gosh. Oh my gosh, this is just, this is just the next level and the information that I've been searching for to try to understand because everything seems so generic. And this a personalized house and yeah, doctor man saw you the president and founder of the DNA company, which is offering direct to public and in conjunction with conditions. A couple of reports. So our full genomic report in a hormone report and I want to tease apart a little bit today, why should people even consider having a look at these, the sort of testing what benefits they can get out of it. Speaker 2: (08:58) And I'd like to also tease a little bit about looking at other, like I've, I've looked at a lot of gene companies and that do gene DNA testing. And you had an analogy on a Bulletproof radio that I heard you on the same show who's amazing Dave and his work that was about the most people are looking at it DNA as a vocabulary and not a language. And that just seems them light bulb up in my head where I realized, okay, so it's not the siloed genes looking at them individually, but looking at cascades and pathways and combinations of genes as we are then interpretation has been missing today. Speaker 3: (09:43) Oh, 100%. So I always say, you know, Lisa, anyone that is in the data business, regardless of whatever data you're collecting, data is really quite dumb. Data in and of itself doesn't mean anything unless you know what to ask of the data unless you know how to triage, how to approach the data. So when we use the analogy as DNA, the operating manual, the genome, it really meets all the classifications and descriptions of a language. Thus far we've been looking at DNA and genetics from a language perspective purely as a vocabulary exercise. The more words we know, the better we presume to think we know the language. And as much as that is important as per the analogy that I drew with on Dave, show a person simply knowing more vocabulary by no means mean they understand the language. And so when it comes to DNA, when it comes to genetics, when it comes to how this awesome operating manual, the architecture of it, it's not just about vocabulary, it's not just about the individual genes. Speaker 3: (10:51) So here are the two layers implicit in your question that we do a bit differently and why we need to do that differently and why it's important that it's done this way. The first is this. When you're looking at the DNA, if the person are either genetic makeup, the vast, vast majority of companies right now, they're looking at things called snips, single nucleotide polymorphisms. In other words, they're looking at places which is absolutely important. They're looking at spelling variations in this operating manual. And of course these spelling variations, these single nucleotide polymorphisms will impart to you mean Jane, Paul, Peter, the same cellular job that we all want to do. These spelling differences can impact the efficiency with which we do that job and that is important to know, but while we're at that point of spelling, you see per any language, if I wrote a paragraph, I might have spelling errors in that paragraph, but there are examples where I may have inadvertently deleted a sentence or deleted a couple of sentences in that paragraph. Speaker 3: (12:00) Now, if the analogy here is that the gene is the paragraph, so your operating manual are these 23 volumes. Think of it. Think of a 23 volume and psychopathic set these awesome, huge volumes. Now we're going to inherit two of these 23 volumes. One from mom, one from dad, and these volumes are properly arranged and when we open up any page, let's say we go to volume three from mum volume three from dad, we open up page four on each of those volumes and we look at paragraph five page four, volume three we, I see the same paragraph. We're going to see the same information from dad's gene paragraphs of genes and mom's gene. We're going to see the same information, but when we look really carefully, when we look at those paragraphs, really collect carefully, we might find that there's some spelling differences. Those are the snips. Speaker 3: (12:57) We may also find that on either dad or mom's paragraph, a sentence was missing and I just taught this over the weekend. So I was in the auditorium and I said, okay, here's an instruction that was waiting for me coming to this auditorium to give this lecture, Dr Mansoor, go to auditorium B and to the left door approach to podium from the right side, press the enter button, begin your lecture. That's an instruction. That's a paragraph. That's an instruction and that's the equivalent of a gene. Now in that paragraph they make has been a few spelling errors or changes that may have confused me a little as to what the instructions are. But when I look at it carefully, I could sort of still figure it out. Okay. But if in that paragraph, the sentence that says go to auditorium B was missing at, of course there are multiple auditoriums, all of the other parts of the instructions are there. Speaker 3: (14:03) But I can really be confused as to what is the ultimate thing that I'm supposed to do. It's called an indel. So in our genes, not only do our genes have slips, many important genes actually have places within them that I'm missing. So until we test for those type of changes, we're by no means getting the full picture of what is happening. The third thing is this, not only do we have slips, not only do we have in Dells, there are occasions where the entire gene is missing is show I'm supposed to show up. I got to the hotel where the conferences are and the instruction just telling me what it's just not even there. So here I'm in the lobby going, I don't know what I'm supposed to do. This example is a genetic phenomenon keeping the analogy, this is called this C and V copy number variation. Speaker 3: (15:03) We see because we were supposed to have two copies of that. Paragraph five page four, volume three. Sometimes believe it or not, when we go to page four we've opened up mum's volume three dad's volume three. There they are. We're going to read both of the instructions cause that's what yourself has to do at any given moment. When there's a job to be done, your cell goes and pulls the volume that has that instruction, takes down a mum's copy, takes down, dad's copy, opens up and reads the instruction. Now in the case of a CMV copying of the variation, we can open up mum's volume three page four there is paragraph one, paragraph two, paragraph three paragraph four paragraph six. Oops, wait a minute. Where's part of our five? It's gone. There's part of four. There's part of six. I look over a dad. He's got all of the paragraphs or vice versa. Speaker 3: (16:02) Sometimes Lisa, both paragraph fives are gone. Okay. So the point of the first answer to your question, why we do things a bit differently is we're not just in the business of collecting data for data's sake. We're collecting data. Are you were doing gene testing to understand a process. When we designed genetic tests, we don't begin with genes. We begin in a whiteboard saying, what is the thing in the human body that we want to study? What is the thing that we want to study? Genetics, just good old fashioned medical textbook, human physiology. Do we want to study the way the newer chemicals are produced and bonding and response? Do we want to study how the human body makes sex hormones? Something we should talk about when it comes to human performance. So how does the male and female body makes progesterones androgens Astros? And then we mapped that out. Speaker 3: (16:56) Forget genetics, which is not about how does the human body do that? No, of course, if the human body's having to do something, then it means there are genetic instructions for that film. So only when we map out the cellular, the cellular biology, the cascade, only when we met that out, then we come in and we pencil it. This gene is responsible for here. This gene is responsible for there such that at the end of the exercise, we've got a genetic test that already tells a story. The result from that genetic test is telling you the entire cascade. Step one, step two. We look at each of those genes that are telling us the story and we ask are these snips that are important? Are there entails that are important? Are the CNVs that are important because all three make a wow. And so the first part to the answer to your question is if you've been looking at genetic tests that are only reporting snips, you are dramatically limiting the variations that you and I and every other person have within our genome. So you're missing the nuances that are in your language to clarify the job to be done. Does that make sense? Speaker 2: (18:16) Absolutely. So that actually puts them together in my head because I've been starting this, I don't know, like for example, the GSTT one gene and the detox and antioxidant pathway, one of those types of genes that can be completely done. Speaker 3: (18:31) Completely. Totally said, absolutely. And of course it belongs to super family. So there are multiple G S T genes, but two minutes on that. If you're going to design the human body and you're going to say, listen, one day we're going to make this thing called human being and we're going to put him or her in this wonderful world, but mind you, he or she is going to have to deal with some toxic insults, both from without and from within. Where would you, and you know that, where would you put your detox defenses? Well, they're about four places. If you're an intelligent designer, you would put your detox, different defenses at least in four places. You would say, how and where do things get into the human body, dermal skin, the nose, nasal Bronxville lung, the GI track. Okay. So those are how things get it. Speaker 3: (19:23) And unsurprisingly you would want to make sure your detox genes and the things that you'd want to make sure there's super active in those places. And then you, you'd also say, well look, at the end of the day, things are always going to get past borders inside of the body, their waste products. So then I'm also going to put a detox organ. The liver, when we go to the human body, this is where we find these detox genes expressing themselves. And each of the GST is have sub specialties. Some of them are more important in the nasal bronchial track, some of them more important in the GI track and so on and so forth. So when you know the story that you want to read about the body, you know how to read the manual and interpret, is the GST T one gene deleted or not? This is a massive implication to the human body. Speaker 3: (20:16) Can you imagine the GSTT one gene is one of, if not the most important bio transforming antioxidizing enzymes in the body per its name and its gene and its enzyme. And if a person doesn't have it, literally it's not in mere manual. The GSTT one gene is on volume 22 and if that paragraph you have not inherited it from either mum or dad, you are missing an enzyme in your body. That is one of the most important detox. Now doesn't mean that you're not compatible with life, but it most certainly means you could not be the person who says, well you know what do you have a metals mean after all they're not that bad. Oh you know what, my uncle smoked until he was 80 years old. I'm going to smoke as well. Well you can't compare yourself to that person cause you don't have one of the most awesome detox genes. Speaker 2: (21:13) You don't have a good defense mechanism. And so like the detox is actually the first port of call before the immune system even does this job. So I'm, I'm excited to get my tests back cause I haven't gotten gotten through the reports yet. I'm, I'm suspecting that I have a problem in my GC jeans because I'm a very young age. For example, I've been the next medic as a, as a severe asthmatic, as a child, and I'm very hypersensitive to smells and anything. So I'm like a Canary one C one, which is theta. Yes, Speaker 3: (21:54) Very important in the liver. Key one PI GSTP one is the one that's really important in your nasal bronchiolar lung cavity. Individuals with a suboptimal P one are at extreme risk of early ectopic asthmas. They're the ones that if they go into the shopping mall, you know, the perfume resection, they've got to avoid the perfume resection. Right? Those are the GSTP ones. Speaker 2: (22:21) Wow. I'm obey. Fascinating to see if that's what comes back. And so if you want it deleted into them, we'll get onto hormones next because I really want to dive into there, but just to, to to look at the GST genes. If you don't have, you either have only one inherited GST, one gene, your mother or your father and you're missing the other ones or you're missing both altogether, are you more likely to have you're more likely to have toxins coming in that you can't deal with as well. And then your immune system is this way or auto-immune or part of the Speaker 3: (22:57) Brilliant, brilliant question. Just before we answer that, I had mentioned there were two layers to differentiate yourself, so just so that we close the chapter on what we do differently. So I'm going to come back and, and so now we will take it forward. We just mentioned that there you have to be mindful of the three different layers of variations, snips in Dalles with pieces of the genome missing and CNVs where the whole gene may be missing. The other quick differentiator, bringing back the analogy of a language, bringing back the story of the human body, it's this, and I told the audience this, there was an audience of clinicians in Phoenix this weekend. I said, have you ever read a really good, you know, suspense novel and not suspense novel, the novel that the author's painting the character and you're thinking he's the bad guy, you know, and he's falling around the heroin and he knows he looks a bit shady. Speaker 3: (23:51) And then until or unless you've read the entire book, you only find out that he was a protector or he was something. He was a guardian and words. He wasn't about that guy. Now what the heck does this have to do with genes? The second player, when we mentioned that we do things differently, we said that DNA is really a language by all of its definitions, with its nuances is this, there are many genes, Lisa, where if you were to look at that gene as a standalone and if you was to look at the genotype of that gene, in other words, what version do you have? You think you have either the best version or the worst version depending, and you may think you have the best version for example, but it is not until you look at a completely independent gene that has nothing to do with this gene, that the version of that independent gene wow colors, whether your actual optimal version of gene a will stay optimal or not. Speaker 3: (24:52) Or conversely, whether you thought you had the suboptimal version of a bad guy, you read the full story, something else tells you what you fought was the bad guy was not the bad guy. Wow. And this is what it's called at peace basis. You see we're all concerned about epigenetics, which is important. FP genetics. How are we reading? Are we actually going to read that paragraph on the page or are we not going to read? That's at the genetics, but nobody's talking about epi. Stacy, this is Stacy. This is often, we've read the page after we've read the paragraph. We cannot yet make a conclusion until we read 10 pages later, 15 pages later, something there. We'll bring it to life. We'll color what we read on page three. Speaker 2: (25:48) Yeah, so, so for example, if you're, if you're looking at a specific gene and it has an, that is say the faster for the sip, 79A1 gene and the hormone a kiss guide. If it's a fast one that's not in and of itself a good or a bad thing. It depends on the other things. It depends on the, so that's what you're meaning. So one of Speaker 3: (26:14) The best examples of that is this, the BDNF gene, the BDNF gene, brain derived neurotrophic factor. What are the most important genes in the brain? Well, in the whole human genome that tells the brain how to secrete this awesome thing that heals the brain. You and I were having a conversation about a loved one, so that loved ones B, D and F was going to be hugely important. And how that loved one recuperated from the challenge that she had met BDNF. Now the beating of gene has an important variation. A snip this time, which is either a G version or a version. Okay. TheG version, Jews and George as in guanine is the optimal version of BDNF, the optimal version. So if you're a GG blessed, that's good. You are naturally predisposed. You have the in Harrods, the innate ability to make more BDNF. Speaker 3: (27:13) And let me tell you that's a good thing. Any which way you slice it. Wow. An independent gene, the TPH to gene the trip to five hydroxylase gene to TPH, two gene, which is involved in how the body deals with serotonin. K two has a sip. It comes in a G version and a T version G as in George T as in Thomas. The G version is considered optimal but hold on. If you happen to be GG fatigue, pH two and GG for BDNF ostensively both those genotypes for each affair genes are optimal, but if you were GG for both, it creates a haplotype. It creates a combination that is an act risk combination and it is, it is the negative combination. It is the, it is the deleterious combination when it comes to certain aspects of human behavior. These individuals, when you're GGGG, they exhibit poor inhibition of negative emotional stimuli. Speaker 3: (28:28) In other words, when something negatively emotionally affects them, their ability to kinship, the ability to say, you know what, I'm not going to focus. I'm not going to hamster wheel constantly play that over and over over again. They haven't, they have a hard time giving up that when something gets under their skin. So to speak emotionally, they have a really hard time getting over it so they have a strong imprint. The memory imprint, very strong EMI, emotional memory imprint and of course the stronger you EMI emotionally memory imprints, the easier you emotional memory recall EMR is because the deeper something is imprinted then the smallest cue. You have a love, you have a partner and you know you love each other to bits, but like human beings, you're going to have your ups and downs. I mean it's where human beings after all, and on one particular evening you were both getting on each other's nerves and she was wearing that beautiful red dress and that was the evening that you both said things you shouldn't have said and it hurts the person who has this phenomena. Speaker 3: (29:36) Whenever he sees his wife, would that red dress down the road, everything's perfect. You, you're going up for a birthday party, you're both happy, it rises back up. He remembers that evening more than he should. It brings back to the surface and vice versa. This is that Paul, inhibition of negative emotional stimuli that lead to profound memory imprinting and therefore profound memory. Recall. The point of all of this and the reason I mentioned this is, and we're going to come back to the GSTT one, was to clarify, you see Lisa, it's not just about even the type of things you're looking for. What matters is the interpretation we sell the combination, we are reading the manual, not just flipping, picking words out. Speaker 2: (30:24) This is we have a calmer is well we are the, the apostrophes are this is someone that is what they would be more prone to PTSD Speaker 3: (30:36) 100 that's the point actually and that is further exacerbated based on the no adrenergic pathway which dramatically increases the risk of PTSD. It is exacerbated based on how quickly they are removing their dopamine and noradrenaline via content. So what happens is you begin to pixelate a picture and you've got a low resolution picture and then the more intelligence information you put in, you start to increase the resolution of that picture. You start to get a clearer picture of the person that you're looking at. But to do so, you've got to know where to pick slate. If I'm trying to get a better look at what Lisa's face look like, I don't really be pixelating your toes. I need to pick slick your face and this, this ability to read intelligently. Lisa, I stress intelligently. Riyadh, human genome. Yeah, that's what we do. We do Speaker 2: (31:35) That is absolutely insane. And they've vacations because yeah, I would have seen, Oh, you've got a G G G is good, but I've just understood that nuance, that combination of things. And now I can't wait to get my reports and my family reports so I could because this helps us also understand like the speed in which you are dopamine is processed and gotten rid off or the speed of which we're saratonin tone and all of these things have a fixed on your personality and that we're not 100% to blame for some of our differences. Speaker 3: (32:12) Oh gosh, no. Gosh, no. In fact, what this needs to do on the one hand, it creates the empathy of appreciating, look, this is how some of this is their predisposition. Now, on the other hand, it is not to create a sense of fatalism. While that's the way I am, I know I have found and I have done. The only thing that I've done, probably somewhat unique and special Lisa, is I have reviewed thousands upon thousands of profiles. In terms of my in the world, most of my peers that work at the level I do would say Dr. Mansoor Probably reviewed the most genomic profiles in the world. I don't know if that's true or not, but I certainly have reviewed several thousand meaning meeting the patient, speaking with their doctor, looking at their health profiles and looking at underlining genetic phenomena to see if we can understand what's going on. Speaker 3: (33:00) You know what I found, at least as a fellow, when you empower a person to understand a predisposition, you, you might think that leads to fatalism, but when you explain the functional reality, it actually does the opposite. It gives the person a sense of ownership and then they can finally say, you know, I have dumped with my entire life, I've been this way and I just, I didn't even know why it was that way. Now that I can even understand what's going on, it gives me some closure. Yes, but it now gives me something to appreciate. I can, I can envision how this is working, how my emotions are working. I can now go, you know what? As soon as I see that stimulus that would have got me on that slippery slope, I'm going to stop. I'm not going to go down that slippery slope because I know if I do, there's no coming back for the next two weeks. Speaker 3: (33:52) So what we've found is that this crew all around it just creates empowerment. Which brings me now to the question that you asked about GSTT one and you are, your connections are on point, Lisa, the connection between the detox mechanism of the body. Here's the threefold, and of course it's a bit more complicated, but it's also remarkable. You can take complex systems, break them down to building blocks and keep the acuity. So there are three building blocks we need to look at when we connect detoxification pathways in the body and the immune system. And the, the only thing missing is the inflammatory system. So the triangulation between toxins and immune responses goes like this. The human body's insulted with whatever. It's insulted with the intentional, the unintentional of our daily lives, those toxins enter the body or they try to enter the body. Step number one, how individually efficient is that person at negating bio transforming, neutralizing those toxins either before they can enter the body, such as in the mucosa of the lung, the alveoli lumen, the the lining of the lung, such as the GI mucosa and so on. Speaker 3: (35:16) And so what can we, can we neutralize it so the toxin doesn't even get into the bloodstream? And of course to the degree that it gets into the bloodstream, can we live a hepatic re detoxified so that at least it does not by you accumulate in the body so that at least it does not reach levels that are unsafe. First step number one now too, there are genes, there are whole gene families, their whole cellular processes, GSTs, glutathione, ionization, UGI, Ts, glucuronidation, methylation, self, phonation and acetylation. These are the major enzymatic steps linked to genetic genes that are responsible for bio transforming neutralizing things in our body, okay? So what we need to do is we say, what is the lifestyle environmental context of the person? What are they getting exposed to? I'll be living in a home that has written with mold, are they living and so on and so forth. Speaker 3: (36:17) Okay, step number one, step number two, how good are they at individually neutralizing those toxins so as to not bio accumulate them to the degree that those, whatever. The answer to that question is we're going to have an individualization and with some individuals are better at getting rid of toxins and others are not. If a person is not genetically, innately efficient, optimal at getting rid of their toxins, then what happens? Well, what do toxins do? Toxins cause cellular inflammation, okay? And they cause inflammation via any number of methodologies. They can inflame cell surface receptors, they can get into the cell and create overproduction of oxidants as they can hamper the energy modules, the mitochondria. That's one of the places you'd never want toxins getting to. And of course they can get into the nuclear eye. They can get into the libraries of the operating manual and they can start to change gene expression. Speaker 3: (37:23) So toxins do all of these things. Ultimately, you see Lisa 15 not even 15 years ago, 10 years ago, if you told that a medical conference, there's this concept of inflammation. You'd have a lot of professionals. Well, come on, you gotta be more specific than that. We actually now know that there is a phenomena called chronic inflammation, and regardless of what stimulated that inflammation, bat bacterial toxin B, it's an inorganic chemical. It be it a physical inflammation. It does not matter the way the sun looks, the way the cell begins to behave when it has been insulted with toxins, with exposures, remarkably is the same regardless of the stimulus. Because chronic inflammation has hallmarks that are similar regardless of the stimulus. Now at that juncture, when the cell is inflamed, when the machinery in the cell isn't doing the job that it's meant to do properly, that cell now starts to be like this pulsing red thing just by analogy. Speaker 3: (38:35) In other words, the body is looking at it going, something's happening in there. It's not behaving the way it should. Okay, so now we're going to have two steps. The body now has an anti inflammatory set of steps to quiet us, to bring the cell back into line cause they Whoa, Whoa, hold on. You're starting to misbehave. There's too much inflammation. This is where it's selling the process known as methylation comes in. Cellular methylation can be viewed. It's a detox reaction by the way, but it is a cellular cascade that is radically responsible for bringing your soul from that humming, inflamed, you know, ticking bomb type of modality back down to acquire essence behavior. That's cellular methylation. Now, to the degree that you're able to do that, because suddenly methylation is a multigene cascade, multiple places where things could be not as optimal as we would like. Speaker 3: (39:36) So to the degree that we then triage, we stratify the patients based on their detox potential. We then stratify them based on their anti inflammatory potential. Now, to the degree that we are not quite yessing that chronic inflammation, this is where the immune system can be activated. Immune system was meant to be activated in acute episodes, not chronic episodes. The more you ask the cell to produce antibodies, IgG, IGA is IGMs, particularly IgGs. The more you keep telling that the body pump out IgG, something's not working right, something is there, which is why chronic infections are now very well understood to be linked to autoimmune diseases. The infection did, did not go away, constantly demanded of the body to produce antibodies. And somewhere along the line those antibodies begin to forget what was the bacteria or what and what was the self. And now we just start shooting friend and foe alike. Wow. This is the triangulation that has become now a focal point of so many diseases. Some diseases being more relevant to the whole, you know, things like lying disease. Do you guys have lung disease down in New Zealand? Speaker 2: (41:05) I think, yes, we do. And I think you know we have a massive problem with like thyroid, Hashimoto's sort of autoimmune diseases, crones, IVs. So this is, this is where the body is actually going in overdrive. So the, the original detox genes haven't been able to do their job because combination. Speaker 3: (41:26) There's that one. Exactly. There's inflammation. Yup. Speaker 2: (41:33) Yes. Speaker 3: (41:33) Methylation didn't do the job that was supposed to do and now we're triggering. So there are meta-analyses meta-analyses that show the deletion of the GSTT one gene or overall poor Ghouta finalization has been strongly linked with ulcerative colitis, Crohn's disease, IBD, strongly linked with ectopic asthma, particularly GSTP one in early childhood asthma. Then of course, if you, if you double down on poor math on poor detoxification with poor methylation, you really start seeing Speaker 2: (42:10) Clinical outcome. Yes. Yeah. So, so if we then we, we, we find out all this about ourselves. We find out we've got either the good or the bad and the ugly. And these combinations are not ideal. Then how, you know, we've got this information now, now we want to know what the heck do I do about this? I can't change my DNA. Of course, all things that these reports that your company does, for example, where it can actually lead to some successful outcomes. Obviously avoiding cigarette smoke or exhaust folk tunes and things your GPS deleted. But, but beyond that, nutraceuticals, new nutrients what can be done to help people. Speaker 3: (42:52) So it starts with, so the first thing I would have to say is we take our reports only so far. So the actual report, we take it to the point of explanation of what's happening. And there are certain recommendations, but the real magic must still come from a trained population, you know? So what, so what we do is through also training a certain class of healthcare providers. We might call them the, the new modern day biohackers. The healthcare providers who are really sniff, they're no longer just, you know, pill pushers. They're looking. So I just wanted to clarify. We take the reports, we explain the systems, we explain what's happening, but we also have to be careful so that people aren't jumping to conclusions and self-treating based. So you still want to have someone who understands the bigger picture. And by the way, that's the second part of what our company does. Speaker 3: (43:47) As per my travel schedule, I'm constantly traveling, teaching people, teaching auditoriums full of doctors who are now saying, listen, if I keep practicing medicine the way that I'm practicing, I'm just dealing with a disease population. I'm not healing people. Okay, so with that minor clarification, now we come to, let me paint a picture, paints a thousand words not to be, you know, blahzay here's what I like people to picture and here's what you would want to picture for yourself. Lisa. Picture slide. Okay, so there's a slide your screen, okay, and a circle. And then picture a circle on that screen somewhere on your screen. There's a circle. Now because you're a human being, your circle is going be on the screen. In other words, this is the screen of all human beings and your circle, you, your circle is somewhere on the screen or what does the circle represents? It represents your genetic makeup, which represents a part of your genetic makeup for whatever biochemical process we were studying. So this circle is Lisa's genomic pathway. Okay. Speaker 3: (44:56) I want you to then think of an equilateral triangle that equal three sided triangle that just perfectly encompasses your circle just perfectly. Your circle is perfectly encompassed just right in that triangle. And the emphases of this triangle are labeled environment, lifestyle and nutrition. Yes. What we're learning and what we're recognizing more and more is other than extreme cases, other than extreme cases, and there are mind you extreme cases where a particular genetic combination was really just a real doozy. And in other words, we're going to see some, you know, with the best of efforts, we're going to see some probably deleterious outcomes. Fair enough. But other than those extreme cases, for the vast majority of us, the spite, any inefficiencies we might have if we find the right triangulation of lifestyle, nutrition and lifestyle, nutrition and environment. If we could figure that out and it perfectly matches, I would circle. Speaker 3: (46:08) This is optimal health. So image, the image of optimal health is when you can find your genomic makeup, your circle for whatever you're studying and contextualize it perfectly within the right for you. For Lisa Laughlin, sir, not for Joanne Felisa. What is leases? Optimal lifestyle, nutrition and environment. Now the problem is, Lisa, when we begin working with a patient, obviously and clinicians with their patients, the vast majority of individuals, they do not know their circle. They don't know what's the economic influence. So they don't, and if you don't know your circle, your triangulation, choices of lifestyle choices, nutrition choices, and environmental choices offers skewed and they are not synergistic with your circle. So first objective of this, did you get that picture? Do you know when people say, well, it depends on your genes, your genes. It depends on how you're using your body. If you are, if you took, if you took five identical individuals, they were, you know, quintuplets identical, contemplative. Speaker 3: (47:27) If such a thing exists in today, the same genes and you give those five people at 35 years old, the exact diet. But if those five, one of them was an ultra marathon runner and extreme sports enthusiasts, the other was a couch potato, I don't know, doing whatever the other was a, you know, an accountant who had a nine to five job. We can exercise worrier, but from Monday through Friday really just goes to work, comes home, eats, goes to that and so on and so forth. Even with the same jeans, you can put the nutrition and an obviously not expect the same outcome because they got to know the genomic legacy. You've got to know what is the lifestyle context, what is the nutritional context, what is the environment or context? If one of the things quintuplets moved from your gorgeous country and move to massive metropolis with, you know, air quality, that breathing for one day is the equivalent of smoking a pack of cigarettes in your beautiful country. Speaker 3: (48:36) He or she may have gotten away with a GSTT one or GSTP, one suboptimal ability. He's living in those, you know, that wonderful country views. He's practicing otherwise good, not eating foods with pesticides and herbicides and so on and so forth. And he was going about life actually, not really realizing there was any suboptimal ability until one day his job took him to a big metropolis somewhere. He lost track of the quality of his foods. He's just so busy. He's day in, day out breathing the equivalent of a pack of cigarettes and then six months into this, all things ELLs as equal, his jeans are equal, but he now starts to show symptomologies that he would never have had any different environment and a nice clean environment. Right? So this triangulation is so important. Now coming back to the specifics, once we understand the pathways, we begin first with the dose. Speaker 3: (49:31) It may seem simple, but it actually enters Lisa into, it's not just about the obvious things that you might imagine. I give the example, Lisa, and by the way, it's relevant to the GSTT one gene. Now, juice, TT. Let's focus on the T one. It's the big sister in the glue, the fine fabric. So GSTT one no, it's what's called a phase two detox pathway. Phase two detox. Because when it talks and enters the human body, we typically go through two steps. We take toxin a, we converted into an intermediate B. Yup. We take B further, convert that to C. C is what leaves the body, the B to C part of the transformation. That's where the GSTs come in. The a to B. This is where your cytochrome P four 50s come in. That's the phase one. Bio transforming enzymes. Now if I were to ask you something, when you say fiber to say, would it be a good practice for person to start drinking a nice cup of green juice? Speaker 3: (50:38) You know, like some juice, juice, broccoli and some maybe put a little bit of a baby spinach in there. A bit of ginger, maybe some cute, cute curcumin at the end of it. Would that be a really healthy drink? Yes. Something I do every day. Beautiful, beautiful. And it is healthy generally speaking. So now someone puts a blog together giving this recipe of something that's ostensibly so healthy and there's this mechanic who works in a shop all day with fuse and so on and so forth. He read this blog, she read this blog and she decides that before she goes to work, she's going to have this beautiful juice. This green juice that they read was so healthy and it was a detox juice and they feel good about themselves. Hold on, hold on. Many of the ingredients and not green juice. Many of the ingredients in that green shoes turn on certain phase one sip four 50 enzymes so as to accelerate the conversion of a to B. Speaker 3: (51:54) Now some of the toxins a that this mechanic was facing in her shop, in the, in the, in the mechanic shop that she was working at, when she converts a to B, we know that the B, the intermediate is truly more toxic than wow. And by the way, she did not know she was a GST one deleted individual. Oh, so what did we do to this young woman? We encourage the things that is that we're getting into her body. When she drove that beautiful healthy green juice, she more rapidly converted her A's into B and then ups B's and to CS very well. Wow. Even something that would ostensibly be really healthy by normal standards. Do you see that's a healthy nutrition on the triangle, but we did not ask what was the environment on the triangle and so now we have skewed her triangle away because her genetics circle, she does not have the GSTT one. Do you get that picture? This is a little bit frightening for people who are listening to this or who might be going well, what's the point being? Speaker 3: (53:16) This is weird. The reports have the super value, isn't it? That's the point. It's, it's actually not discouraging. It's, it's finally, and this is all gold. It's finally meant to unravel those nuances that there is such a thing. Have you been? How many of us, you know, we do something that 20 or the coworkers swore was the best thing since sliced bread and then we tried it and not only did it not work, we actually felt like crap or less healthy, and we, we're all aware of this until it's what is it led? It's led for most of us to become numb. We're just kind of get to that point where we're like, well, I don't know what's right for me or run for me. Plus today it says one thing tomorrow it says another thing. So creating some sanity from this confusion is what this goal is about and it can be done. Speaker 3: (54:11) Lisa, when you take your time to read things, intelligent meals, explain things. That's why we've got these epiphany moments that constantly, I like my consults with patients because I feed off of the energy. When a patient just, you see that epiphany admission and they light up and they go, Oh, that's why this hasn't been working with. That's why that was better for me. That's why I took methyl B12 because everyone's telling me methyl B12 is the best version. But every time I take methyl B is it just in my head. I get a headache every time I take micro B12 I get a, and then I go, no, actually I got one too. I can't take methyl before. That's an actual thing. I can't take methyl B12 because my methylation cascade is inconsistent with me taking methyl Beto when I take a dental Sobe 12. Oh, completely different. Speaker 2: (55:07) Wow. So this is getting really granular for each individual. And this is what makes me so excited. And, but before we go on, we have to go and cover off the hormone report. This is something that I and, and this is, you know, for me and any woman, but I wanted to focus a little bit more in on the woman. We've got very complicated hormones, households, but this was the cascade for men and women is very, very similar, isn't it? Yes Speaker 3: (55:33) It is. It's just remarkably, this is what we taught at the cost on the weekend after introducing genomics, it was the first open to eyes that the cascade, the circadian rhythm with which the human body converts progesterones into androgens, androgens to estrogens, men, we do not have a monopoly over androgens. Women, you do not have a monopoly over estrogens. In fact, your estrogens come from androgens. Men, we have estrogens. It's just a matter of the circadian rhythm. When is it happening? How quickly is it happening? And of course, ultimately how much of any of these hormones are produced. And then the final component is how responsive are you, the the woman's body, all things equal. She's designed with the estrogen receptors to be more responsive to estrogen. She responds to androgens as well. Conversely, for men. Now keep in mind something as simple as, I can't believe how many clinicians do not realize how an androgen or estrogen receptors. Speaker 3: (56:32) Now let's stop there for this cascade. We can talk about all of the things about how hormones are produced and how they're metabolized and so on and so forth. But ultimately, how is estrogen affecting your body? Lisa, you're a young woman. You're making estrogen as if you're menstruating or if you want hormone replacement, there's likely some estrogens in your body, one way or the other when estrogen binds to your estrogen receptor. And to the degree that that can happen, mind you, because there are variations to that fidelity, this complex estrogen. So the estrogen receptor androgen to Stastrom, DHT to the androgen receptor. These complexes are some of the most potent DNA transcribing complex. They go into the nucleus and the churn on genes. This is how estrogen and testosterone impacts the human body. They live. They're not just, I don't know, causing breast development or, or, or, or Andrew demise in the book. Speaker 3: (57:39) They do that by churning on the genes that cause the cells to behave in a more underutilized manner or more estrogen. So the first thing I want, our audience needs, our clinicians, we need to re re climatize reacquaint ourselves with that. These hormones potently DNA transcribing, they go into the nucleus and they turn on and off genes. That is why they are not to be dealt with trivially. Number one. Number two, in a menstruating woman. Now I just told you when estrogen enters a cell, I did binds its receptor. It's not just staying in the, in the Maloo of the South, it's going in to the volts, the nuclear volts and churning on and turning off genes. Wow. When you look at the ministerial cycle of, of a, of a relatively normal, repeatable menstrual cycle, you will notice something radically important over the course of 28 days. Speaker 3: (58:43) The human female body isn't exposed to estrogen at the same amount every day, not at all. The human female body in 20 days only has about a six day or so window in which your estrogens that are really elevated and then it comes down. In other words, what is this telling us from a human biology perspective? It's saying that the type of gene expression changes the epigenetic phenomena that estrogens cause on your operating manual. You don't want that to be consistent and constant across the month, and this is very frightening when you look at contraceptive pill or hormone replacement therapy. So it's most certainly very frightening. That is not, let me be clear. That is not to say that there isn't a place or a time for these things. You know they are absolutely a young woman has to have the right to how she treats her body and what she does. Speaker 3: (59:47) But there is a place in time you at least be equipped, at least be empowered before you make this decision as to a knowing what it's doing for you. Say, okay, look for these few months of my life, for these couple of years of my life, this is going to be a bit more important that I take these precautions, for example, but you should know that to do so indefinitely, month after month, year after year. Now they've got clinicians encouraging young woman not to even have a bleed through. There's no point for even the bleed. So just stay on the, you know, constant level, 24 seven three 65 15 years. How is this compatible with normal human physiology? When you understood what I just said? Yep. Now let's go a step further than that. You see estrogens do what we just said. They bind their receptors, they go into the cell so they go into the nucleus. Speaker 3: (01:00:47) They change gene expression as they're meant to for brief periods during the month. Fair enough. Now, once those estrogens have done what they've done for those days, then the point of it is there's a circadian rhythm. The body breaks down those estrogens metabolizes them by a transforms them so that they're no longer active. They've been neutralized, and then we hit repeat, rinse and repeat, and we start a new cycle. But here's the point. Every a woman, Lisa, every a woman, a man for that matter, but let's focus on the ladies when she made her estrogens or she took her estrogens, because even whether you take it or whether you make it innately or you take it, it doesn't matter. You've got to metabolize the estrogen. Now, every young woman can metabolize estrogens into three byproducts. I estrogen 400 Z estrogen, 16 hours for hydroxy estrogen. Every human being does this, and this is a crucial point. Speaker 3: (01:01:49) Absolutely. But these three metabolites do not impact yourselves in the same way you say. If you thought of it, you've made the estrogen small window. Now you want to neutralize it so that the body isn't under its constant influence. So you want this metabolite, this estrogen, this hub light to have lost bind to the receptor. You want it to last. It's estrogen Ising properties. Lo and behold, four estrogen, one of those three metabolites retains the ability to bind the estrogen receptor. In fact, some studies show it might be an even more potent comm when it, when it binds and it creates this, this common, a tutorial, Leiden and receptor, it's DNA. Transcribing effects are even more potent, much like the analogy between DHT and the androgen receptor versus testosterone. DHT dihydrotestosterone, which is a metabolite of testosterone, has a higher potency binding affinity to the androgen receptor. Speaker 3: (01:03:00) Four hydroxy estrogen is to the estrogen receptor as DHT is to the androgen receptor. Wow. The ability innate tendency of a young woman when she's faced with estrogens to make either the two hydroxy which is considered protective because has lost or the four hydroxy that inmate differentiation is radically genetically determinable. Now, if something as simple as that, Lisa, when you stitch these things together, when you understand, look, estrogen should be my body needs security and rhythm. I do not want estrogen is constant. When I break down those estrogens, I want my body to have had a break from them. And you did not know whether you were four hydroxy dominant or not. If you had a tendency to make more of the four hydroxy than the two and why is four hydroxy so naughty? Three reasons. A, it binds the estrogen receptor, not giving your body a break from the estrogen ization one to four hydroxy estrogen if you are not flushing it out of the body and how do you flush out for drugs, the estrogen through methylation, the comp gene, which is catechal methyl transfers an oops. Speaker 3: (01:04:29) Can you imagine if you were innately genetic info, hydroxy dominant and have the slow comps because now you're making too much four hydroxyestrone you have a tendency to do so. You do not have the enzymatic ability to get rid of it. Now you buy your stagnate, your four hydroxy Astrid. Do you know what full hydroxy estrogen does other than binding the estrogen receptor and Quinones? Quinones? Listen, my God, you're speaking more than some of the best medical biologists that I've spoken to. So the, the decompose into Quinones and do you know what Quinones do? They get into your DNA. They stick to, they are mutagens. They stick to your DNA, causing the DNA to not be able to unravel and repair itself and by the Quinones then cause accidents. So here's what you don't want to be. You don't want to be the young woman who is genetically predisposed to overly produce four hydroxy estrogen simultaneously, have a poor comp, simultaneously, have a low GSTT one GSTP one, which was the thing, Quinones, and then have a poor mitochondrial superoxide dismutase or antioxidation to get rid of the oxidants Speaker 2: (01:05:52) And add to that. You're in your forties or your 50s and you're making more EstroZen, Speaker 3: (01:05:57) Which is a breast tissue because it's not in the liver anymore. The liver organ, at least it was designed for that type of metabolism. You're doing this in the breasts, you know, God forbid. Okay, Speaker 2: (01:06:10) This is where the cancers can come in Speaker 3: (01:06:13) This is weird and just why we have the the epidemiologic rise during that shift where the woman's body shifts from doing that grunt work in her liver, which was designed for it to doing that grunt work in such as breast tissue, cervical tissue, an ovarian tissue and so on and so forth. Which of course the human body, the female body does not express estrogen receptors, the same level for every cell type. You know, when you were, we lobby at nine years old and you could have gone outside, you know, flat chested like any other boy and you know, and then when, when men awe kits and the body changed your elbows and forms didn't change, it was suitable zone. Those are the zones that have more estrogen receptors. Speaker 2: (01:07:03) And this is so this is how we can see like when you're looking at the phenotype, if we can go look like the the the hormone cascade just for people that are listening, it's going from producer owns and pregnenolone's into testosterone's which can sometimes go into DHT and which then go into the estrogen. Is thrown in your estradiol if you're pregnant when you're older you have more strokes coming in which are, that's coming from the the other top of testosterone isn't it? One on one and then it's means a lighter than these three path rates into the two hydroxy four h
This Sunday morning, songs include ‘Oh What a Beautiful Morning’, ‘The House I Live In, a LIVE performance of ‘Luck Be a Lady’ and ‘I Sing the Songs’. Plus, conversations with Frank’s road manager Tony Oppedisano and actor and singer Donny Most! It all starts at 6:30am CST on AM720, wgnradio.com or tell your smart speaker to ‘play WGN […]
Episode 4: I Sing the Body Baguette by Evan Criscuolo
It should have been a pairing that was written in the stars, but why did it take three seasons for Ray Bradbury to enter The Twilight Zone? And why did he never return to classic Twilight Zone again? Join Tom Elliot and special guest Amy Boyle Johnston, author of Unknown Serling, as they examine the story, but also the story behind the story of I Sing the Body Electric. The post Serling, Bradbury and The Body Electric appeared first on The Twilight Zone Podcast.
Tony hits the beach, while Paul gets meta with follow-up. Tracklisting: Hammered Hulls – Written Words [S/T] Peter Mayburduk – Apart! Together [single] Cecily – Clumsy [Awakening Pt. 1] The 5:55 – The Edge [The Five Fifty Five] Bumper Jacksons – I Sing the Body (Live) [Live at Wolf Trap] The Andalusian – Dance to […]
iDance Adaptive Performing Arts Center is a non-profit organization providing students with instruction to use creative expression in the performing arts. Our Passion is our Technique.iDance APAC offers a diverse curriculum for students regardless of age, race, gender, ethnicity or disability. iDance provided community event entertainment and has received regional awards and recognition for community inclusion. Class are held throughout the week with performances scheduled throughout the year. iSing is an adult vocal performance group that welcomes all vocal abilities. iSing hopes to inspire wheelchair bound and vision impaired individuals to participate and share their love to be outspoken.The iFit Gym gives our families more opportunities to strengthen healthy habits to benefit individuals in the special needs population. Participants are seeing and feeling the benefits of being connected to fitness while having a lot of fun. The classes are full of laughter and energy when families bring friends to share the experience.In addition to our already existing dance, singing, acting, fitness and wellness programs, we will now be offering a Day program, Homemaker Personal Care (HPC) services and Respite Camps to individuals served by the Lucas County Board of Developmental Disabilities.For more information on our new services, contact Karen Medina at 419.309-1610 or email info@iConnectOH.org.
Message: There is a Generation Mission Moment: Eddie and Carrie Ramos – Dominican Republic Songs: Father, I Adore You; I Sing the Mighty Power Host: Dr. Brian Albrecht Memory Verse: Psalm 2:1 The post Hon. EC Manning – There is a Generation appeared first on Canada's National Bible Hour.
I don't sing. I Sing badly. I had this idea one night so I went line for line just for giggles and shits. Enjoy. You should probably watch Lil Dicky's Earth before listening to this.
Brian Keene reads the short stories "I Sing a new Psalm" and "Something Pretty".
Nicholas Delair LaDuke (Nick) Birthdate August 25, 1984 (34) Born in Pleasanton, Ca Currently based out of Livermore, Ca Mother Sue McKinnon Father Jim McKinnon (step Father that raised me from 5) Born with Wolff Parkinson White Syndrome, 6 years old diagnosed with Epilepsy Graduate of Sociology from the University of Nevada Las Vegas -Two time West Coast Region champion NIRA 2005 and 2006 -Short Round Qualifier CNFR Mesquite series champ 2012 -California Circuit Champ 2017 -World standing 29th 2017 -Two time SoCal Pro Rodeo Series Champ -First Pro Rodeo Win Folsom, Ca in 2003 -Qualified for my first Rodeo Houston in 2008 PRCA’s Industry Outreach Department under Director Julie Jutten since 2013, speaker at camps and fundraisers from New York to Southern California. Part of 2009-2010 managed the Bottled Water Department for Ising’s Culligan Water Hit a record for route sales with my division in the heat of the recession in California. Rest of time spent riding horses on the English and Western side of things for World Champs on down to back yard horse owners (2004-2008, 2010-2015) Fun fact only got to be around horses 2 weeks out of the year from birth until I was 14. (Got on two calves when I was six, went on a medically forced break, and then did not get another opportunity to pursue my dream until I was 14) Trained Brazilian Jiu Jitsu under Travis Tooke, Houston and Darlynson Lira, California off and on since 2011 and have been cross trained in Combat Sports/Martial Arts off and on since I was 12 years old. Resources: Follow Nick https://www.instagram.com/nick_laduke/ (https://www.instagram.com/nick_laduke/) Show Music: “The Ropin Pen” (Live) by: Trent Willmon https://www.trentwillmon.com/ (https://www.trentwillmon.com/) MC Podcast Production & Editing: Matt Kirschner https://www.righttracmedia.com/ (https://www.righttracmedia.com/)
Aaaaaaaand we're back! The brothers have reconvened to dive into three episodes about some not-quite-human characters, and the people who love them. Which of Serling's "Robutts" would you want to hang out with? Join us for deep dive into "The Lonely", "I Sing the Body Electric" and "In His Image" and hit us up on facebook with your thoughts!
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