Podcasts about maloo

KURT MALOO “THE CAPTAIN OF HER HEART” MEGA HIT- SWISS SINGER-SONGWRITER-COMPOSER-MUSICIAN-RECORD PRODUCER ZOOM EXCLUSIVE SPECIAL EDITION WITH RAY SHASHO Hello everyone and welcome to another edition of Interviewing the Legends I'm your host Ray Shasho. In the 1980s, as one half of the brilliant pop duo Double, Kurt Maloo coauthored and sang the most enduring hit Switzerland has ever produced: “The Captain of Her Heart.” “The Captain Of Her Heart” remains a firm favorite and is still part of Maloo's live repertoire. Internationally the most successful Swiss song of all time and regularly makes it into the jazz and pop download charts throughout the world. The song captures the moment when a woman realizes she can no longer wait for the man who has won her heart, but must move on to a new life, “as the day comes up.” This melancholic optimism is central to both Maloo's poetry and his music.  “Off The Record” is Kurt Maloo's latest project a collection of songs released on an EP starting with volume 1 released in 2023 and volume 2 released this year. Reviving his 1966 Fender Strat and singing in Spanish (for the first time) on one of the songs, might not be what you were used to hear on his previous albums. But the new songs will constantly grow on you. Their fresh and intriguing atmosphere is providing the perfect background for Kurt's warm and comforting voice. PLEASE WELCOME SWISS SINGER-SONGWRITER,COMPOSER, AND RECORD PRODUCER KURT MALOO TO INTERVIEWING THE LEGENDS … PURCHASE ‘OFF THE RECORD' VOLUME 1 and VOLUME 2 BY KURT MALOO At amazon.com   FOR MORE INFORMATION ABOUT KURT MALOO VISIT https://kurtmaloo.com/ Official website https://www.facebook.com/kurtmaloopage Facebook https://www.youtube.com/kurtmaloo YouTube https://www.instagram.com/kurtmaloo Instagram KURT MALOO Discography Off The Record, Vol.2 (2024) EP containing a remake of “Life Could Not Be Better” and a surprisingly up-tempo ballad “Solitary Love”, with a radio edit of the latter. Off The Record, Vol.1 (2023) EP City Of Rain (2016) Single What About (2014) Album Summer Of Better Times (2010) Album Loopy Avenue (2006) Album Soul & Echo (1995) Album Single (1990) Album Double – DOU3LE (1987) Album Double – Blue (1985) Album Double – Woman Of The World (1984) Single Double – Rangoon Moon (1984) Single Double – Naningo (1983) Single Ping Pong – From Exile (1981) Album* Luna, Luna & 7 Notorious Maloo Homeworks (1980) Album* Giant Lady (1979) Single*           Support us on PayPal!

पूरा Podcast यहाँ देखें: https://youtu.be/YmhdyCdbOjg?si=x7r43dLC_y_ZlKt4 BeerBiceps SkillHouse का Course Join करने के लिए यहाँ CLICK करें : https://bbsh.io/podcasting-101 BeerBiceps SkillHouse को Social Media पर Follow करे :- YouTube : https://www.youtube.com/channel/UC2-Y36TqZ5MH6N1cWpmsBRQ Instagram : https://www.instagram.com/beerbiceps_skillhouse Website : https://bbsh.in/trshindi-launch-cpyt For any other queries EMAIL: support@beerbicepsskillhouse.com In case of any payment-related issues, kindly write to support@tagmango.com Level Supermind - Mind Performance App को Download करिए यहाँ से

Watch all our other adventure podcasts here:- https://www.youtube.com/playlist?list=PL9uK6jbdzfVdbcQPJNUkL_dowMKT3bd5E BeerBiceps SkillHouse का Course Join करने के लिए यहाँ CLICK करें : https://bbsh.io/podcasting-101 BeerBiceps SkillHouse को Social Media पर Follow करे :- YouTube : https://www.youtube.com/channel/UC2-Y36TqZ5MH6N1cWpmsBRQ Instagram : https://www.instagram.com/beerbiceps_skillhouse Website : https://linktr.ee/BeerBiceps_SKillHouse For any other queries EMAIL: support@beerbicepsskillhouse.com In case of any payment-related issues, kindly write to support@tagmango.com Level Supermind - Mind Performance App को Download करिए यहाँ से

Anurag Maloo is a Mountaineer, Entrepreneur, Business & Climate Athlete, and Keynote Speaker based in India. He had narrowly survived a fall into a crevasse at an altitude of around 5,800 meters on the eight-thousander Annapurna in western Nepal. He was rescued from the crevasse three days after he disappeared. Anurag is a former Teach for India fellow selected as the 2041 Antarctic Youth Ambassador and invited to join the polar pioneer, Robert Swan (OBE, FRGS) on the 2041 Inspire International Antarctic Expedition in 2013.   Get Inspired, Be a Doer.   Viewfinders Podcast page: https://viewfinders.com.np/podcast-as-a-service/

In this episode of Paisa Vaisa, host Anupam Gupta talks with Mangalam Maloo to uncover the fascinating business model behind the Indian Premier League (IPL). He dives deep into the economics of the IPL, exploring how it functions as a lucrative business for the BCCI and individual teams and also about the insane amounts of money involved in broadcasting rights and the advertising frenzy that surrounds the IPL season.This episode is packed with insights for cricket fans, business enthusiasts, and anyone curious about the financial powerhouse that is the IPL. Don't miss it!Get in touch with our host Anupam Gupta on social media: Twitter: ( https://twitter.com/b50 ) Instagram: ( https://www.instagram.com/b_50/ ) LinkedIn: (https://www.linkedin.com/in/anupam9gupta/ )You can listen to this show and other awesome shows on the IVM Podcasts website at https://www.ivmpodcasts.com/ You can watch the full video episodes of PaisaVaisapodcast on the YouTube channel.Do follow IVM Podcasts on social media. We are @ivmpodcasts on Facebook, Twitter, & Instagram.See omnystudio.com/listener for privacy information.

This episode has one of the greatest stories from the world of Mountaineering. Anurag Maloo is an Indian climber who went on an expedition to climb Mount Annapurna April last year, but an accident happened and he feel into a deep crevasse. Multiple rescue attempts were made but with no luck for 3 days. So, Anurag was stuck inside of a narrow crevasse, injured from the fall, at an altitude of nearly 6000Meters on one of the deadliest mountains on the planet that has an extremely high fatality rate.  After 3 days and 3 nights, an attempt was made to recover his body, and a team of skilled climbers manage to get inside the crevasse. To their shock and awe, Anurag was still breathing. That set off a race against time. A race to save his life.  An entire community of people from 60 countries came together and contributed in different ways to one cause - #bringanuragback How did this happen? How did he survive? What had exactly happened? How is he now? What has this life changing experience taught him? Not just this, how's he as a person? What's his life story? Why does he climb? What's his life like outside of mountaineering? Tune in to the full episode to know all these answers, and more in this inspiring episode of the Find Your Ultra Podcast. Follow Anurag on Instagram https://www.instagram.com/anuragmaloo/ Follow Anurag on LinkedIn https://in.linkedin.com/in/anuragmaloo Rescue team of Anurag: Adam Bielecki - www.adambielecki.pl Mariusz Hatala - instagram.com/hati_mountain_addicted Chhepal Sherpa Lakpa Nurbu Sherpa Dawa Nurbu Sherpa Lakpa Sherpa Tashi Sherpa Coordinated from Base Camp by Chhang Dawa Sherpa and Sobit Gauchan was the helicopter rescue pilot #Anuragmaloo #Survivor #FindYourUltra #Mountaineering #Rescue #Miraculousrescue #Storiesofhope #Courage #Nevergiveup

Let's begin with what the cues were overnight. Wall Street saw a strong close, with Dow Jones ending 0.5 percent up, S&P 500 up almost 1 percent, while the Nasdaq continued to march forward. Nasdaq was up 1.5 percent, led higher by Apple. After it unveiling the Vision Pro last week, the Apple stock has been on the tear. Yesterday as well it hit a fresh all-time high with the market cap of the tech major nearing almost $3 trillion. That's not all, we have a lot of data to watch out for this week. Starting with tonight itself. All eyes will be on the US May inflation data where you're expecting 4 percent inflation in May, which would be an increase of 40.1 percent month-on-month. This is extremely important largely because the US Fed meet outcome is contingent on the way. The Nifty has been ranged around 18,600-mark.The important part is that we found resistance at levels closer to 18,700, whereas support has come in as low as 18550 itself. Meanwhile, the FIIs sold for the second day in the cash market on Monday and sold around Rs 627 crore. Domestic institutional investors bought around Rs 1800-odd crore. There is nothing really to worry about, but a trend that we have to monitor closely. Today is also a Tuesday, which means it is the Nifty financial services expiry today. In the last hour, we will watch out for HDFC twins. Watch out for ICICI Bank and Bajaj Fiserv. These stocks account for the major rate on the financial services index. The Nifty Bank closed mildly below its 20-day moving average of 43980, so that's a level we expected to cover in the first hour of trade itself. Whereas the Nifty will find firm support at 18454, which is its 20-day moving average. In terms of stocks to watch out for, keep an eye out on the oil marketing companies and the oil companies as Brent slipped to $72 overnight. But importantly, watch out for Zee as the SEBI has barred Subhash Chandra and Punit Goenka to hold any key managerial position in the company. Does that change things for the Sony-Zee merger or not? It's something we'll be watching out for. Tune in to Marketbuzz Podcast for more news and cues ahead of today's session

It's the Battle of the Finance Bros on Just A Filmy Game Show as our host Antariksh Takkar, is joined by the host of Paisa Vaisa - Anupam Gupta, and Asst. Editor & Anchor at CNBC-TV18 - Mangalam Maloo!They go at it in the battle for the title of the Biggest Bollywood Deewana, share some absolutely fascinating trivia and stories about some great classic films, and altogether contribute to a riot of an episode.Tune in!    Follow Antariksh on Instagram: https://www.instagram.com/antariksht/ follow IVM Pop on Instagram: https://www.instagram.com/ivmpop/ Follow Mangalam on Instagram: https://www.instagram.com/blitzkreigm/?hl=en Follow Anupam on Instagram: https://www.instagram.com/b_50/ This Show is Available across audio Platforms:  Spotify | Gaana | Apple Podcasts | Google Podcasts See omnystudio.com/listener for privacy information.

Indian climber Anurag Maloo was miraculously found alive last week after spending three days inside a crevasse on Annapurna. The remarkable rescue required a team to brave one of the most dangerous spots on the mountain amidst bad weather to airlift him out. What began as a body retrieval effort on Annapurna last week turned into a miraculous rescue, when Polish climber Adam Bielecki rappelled 60 meters into a crevasse where Indian climber Anurag Maloo had fallen three days earlier. Imagine Bielecki's surprise, when expecting to find a lifeless body, to learn that Maloo was alive. In this episode taken from Everest Mystery I'm going to share more of the dramatic footage from that remarkable rescue on Annapurna last week. This story has captivated the mountaineering world, for me personally it has touched a deep nerve….I'm so grateful to learn of a story in the mountaineering world that is filled with hope, love, determination, courage and survival….with a good ending.Here is the link to this episode on YouTube, our Everest Mystery channel:https://youtu.be/dWiqw-T2cE8And more from the Nepal Himalaya, Everest updates and news you need to know.Peace and Blessings,Thom

HERE'S MY FULL CONVERSATION with Alan Arnette on YouTube:https://youtu.be/WIk67aEg0sIThere's Been Loss of Life and Intense Drama on Annapurna and in the Mount Everest and 8000 meter peaks region of the Nepal Himalaya. A veteran climber is dead, another miraculously rescued, and multiple others are lucky to be alive after a tragic few days in the Himalayas.As the deadliest of the 8000 meter peaks Annapurna has of late become an object of desire for a wider and larger group of the new era of mountaineers, ticking off peaks on their checklist.In recent years, guides have supplied high levels of support and supplemental oxygen to make the peak more accessible to less experienced climbers. Of the 395 total summits, 129 (33 percent) have occurred in the past three years.HERE'S AN INTERVIEW with one of the world's most respected chroniclers of Mount Everest, Alan Arnette WHO is reporting on this spring's Everest and Himalayan climbing season for OUTSIDE ONLINE We'll talk about the miraculous rescue effort on Annapurna where Indian climber Anurag Maloo was found alive after spending three days inside a crevasse on Annapurna. Angela Benavides of Explorers Web has reported that Maloo was 50 meters in the crevasse, found barely alive by a rescue team led by Adam Bielecki - mind boggling….defying all odds…hope to bring more on that soon.As well as the loss that sent shockwaves through the himalayan climbing community, the ever popular and 10-time Everest summiter, Noel Hanna of Ireland, 56, died in his tent at Camp 4 after summiting without supplemental oxygen. We also discuss the summit of Manaslu by Felix Berg, as well as the sherpas expanding role in the world of 8000 meter peak guiding. And Alan has written a book.YOU CAN FIND ALAN'S BLOG at alanarnette.com Support the show

Kurt Maloo von Double über den "Captain of her heart": «Eigentlich wollte die Plattenfirma 1985 einen ganz anderen Song aus dem Album veröffentlichen, als dann aber die Sekretärinnen im Plattenfirma-Büro das Lied summten, dachten wir, wir müssen es mit diesem Song als Single riskieren.»

Musician Maylee Todd is the guest this week and talks with Doug and Brent about zones and clown juice and how to show a tourist around Los Angeles, among other things. In Unzipped, they talk about fake girls. For extended Poundcast episodes (Unzipped), subscribe on Patreon: https://www.patreon.com/poundcast Follow The Poundcast on Instagram and Twitter @thepoundcast For video, check out: www.youtube.com/thepoundcast Join the Poundcast Discord here: discord.gg/GnqUMmX New Pound House "Dope Beats" Pins right here: https://www.rockinpins.com/product/pound-house-dope-beats-enamel-pin Thank you to our #sponsor Better Help, easy and affordable online therapy. Get 10% off your first month at https://www.betterhelp.com/poundcast And use the code word "POUNDCAST" at www.louisvilleveganfoods.com for, that's right, 20% off!

Trunks Maloo is a mighty elephant that roams the savannah thinking that because he is so big and strong he can do as he pleases. He soon gets himself into a bit of trouble, and quickly discovers that everyone needs help from time to time. It takes one of Africa's smallest animals to help him realize that we are all connected and that we all need to be kind to each other.

Nuutjob is an intimate hygiene brand for men started by two sisters. Stemming from a thorough research on health and wellness products available for men, the brand aims to provide complete hygiene solutions for men to prevent infections and ringworms. The pharmaceutical, health and wellness brand has also been featured on Shark Tank India for serving an under-served consumer market. In this episode, we talk to Ananya Maloo, the Founder of Nuutjob. From understanding the challenges they faced as women founders in market research to how they have taken on a unique tone of voice to educate their audience in a fun manner about intimate hygiene, we deep dive into their social media strategy and how they keep up with all the trends despite the industry they are in. Tune in! Visit their website to know more.

Multi-talented Canadian musician, producer and 3D artist Maylee Todd has just released her concept album MALOO, where she performs as a self-animated avatar of the same name. It's truly weird and wonderful. And this episode is full of unusual and hilarious twists and turns. Find out how a laundry mishap nearly destroyed a prized piece of studio gear, how she comes up with voices for characters in video games, and which of her beloved instruments she would never sell, even to Randy Jackson.Season 4 is sponsored by EVO by Audient: https://evo.audio/STUFF WE TALK ABOUT (SPOILERS!)https://musictech.com/features/studios/show-off-your-studio-maylee-todd-la-maloo-stones-throw/https://www.daz3d.com/https://en.wikipedia.org/wiki/Yamaha_Tenori-onhttps://en.wikipedia.org/wiki/Toshio_Iwaihttps://en.wikipedia.org/wiki/Will.i.amhttps://www.networkworld.com/article/2222575/data-center-steve-jobs-lsd-habit-why-he-indulged-in-marijuana-and-his-1975-arrest.htmlhttps://asia.toto.com/products/toilets/https://p-vine.jp/https://evo.audio/products/audio-interfaces/evo-16/overview/https://en.wikipedia.org/wiki/Eugene_Levyhttp://www.guitarrasmorales.guitars/en/guitar-players/caetano-veloso-guitar-of-paco-de-lucia/https://www.akg.com/Microphones/Condenser%20Microphones/C414+XLII.htmlhttps://www.lyonhealy.com/harps/salzedo/https://www.dynaudio.com/professional-audio/m-series/m3xehttps://www.rokoko.com/products/smartsuit-prohttps://www.xsens.com/motion-capturehttps://www.oculus.com/experiences/quest/https://www.worthpoint.com/worthopedia/roland-mks-juno-107-tr-707-vintage-127232118https://www.vintagesynth.com/ensoniq/ts10_ts12.php

On this episode of 'The Ideas Project', Anupam is joined by Priyank Shah and Mangalam Maloo. Priyank is the Founder of Beardo & of Renee Cosmetics, one of India's biggest men's grooming products brands, and Mangalam is an accomplished assistant editor & anchor at CNBC-TV18. They join Anupam to talk about the current shift being seen towards D2C in the FMCG sector. Direct-to-Consumer has seen a big uptick recently, with notable traditional FMCG companies investing in or building D2C and online-first brands. Is this trend here to stay? Or was this only a fad born out of the pandemic? Tune in and find out.This show is powered by smallcase.Check out the ‘FMCG Tracker' smallcase here: https://link.smallcase.com/RwvWPwpxGqb Download the smallcase app here to start investing!PlayStore (https://bit.ly/3uKFuc7 )AppStore (https://apple.co/3ApbA0o )To know more about smallcase: (https://www.smallcase.com/ )Facebook: (https://www.facebook.com/smallcaseHQ )Twitter: ( https://twitter.com/smallcaseHQ )Instagram: (https://www.instagram.com/smallcasehq/ )YouTube: (https://www.youtube.com/c/smallcase )Linkedin: (https://www.linkedin.com/company/smallcase)You can follow Priyank on his social media:Linkedin: (https://www.linkedin.com/in/priyank-shah-18369237/)Instagram: (https://www.instagram.com/jacobprix)Twitter: (https://mobile.twitter.com/jacobprix)You can follow Mangalam on his social media: Linkedin: (https://www.linkedin.com/in/mangalam-maloo-a83a3815/)Instagram: (https://www.instagram.com/blitzkreigm)Twitter: (https://mobile.twitter.com/blitzkreigm)Get in touch with the host Anupam Gupta on social media: Twitter: ( https://twitter.com/b50 )Instagram: (https://www.instagram.com/b_50/ )Linkedin: (https://www.linkedin.com/in/anupam9gupta/)You can listen to this show and other awesome shows on the https://ivmpodcasts.com , the IVM Podcasts app on Android: https://ivm.today/android or iOS: https://ivm.today/ios, or any other podcast app. See omnystudio.com/listener for privacy information.

Maylee Todd on her meditative, ambient debut for Stones Throw Records, Maloo, being roommates with both a ball python and her friend Eric Andre, exploring the discontinued sequencer, the Tenori-on, future plans, and more! Supported by you on Patreon, Blackbyrd Myoozik, Pizza Trokadero, the Bookshelf, Planet Bean Coffee, and Grandad's Donuts. Support Y.E.S.S. and Black Women United YEG. Follow vish online.Support this show http://supporter.acast.com/kreative-kontrol. See acast.com/privacy for privacy and opt-out information.

Making a great impression is always seen as an outside thing where the emphasis is always laid on good clothes and communication style. But men's impression can't also be affected due to their unknowing actions like scratching the crotch area. Scratching the crotch area may seem like a general thing but it can be caused due to poor intimate hygiene levels that can be dangerous for men's health. In this episode Nuutjob India's founder & Shark Tank India fame Ananya Maloo shares the importance of including intimate hygiene in a daily grooming routine in a detailed chat session with BestForHim's anchor Bhawana. To read more about Men's wellness and health, log on to http://www.bestforhim.com. Connect with us at Instagram, Linkedin, Twitter & Facebook

Nuutjob, a male intimate hygiene product company was featured in Shark Tank India and while they picked up funding, they also received great love and support from the Sharks and the audience alike. We spoke to Ananya and Anusree, the Maloo sisters about their experience in the tank and also on their journey of building Nuutjob. They share some superb incidents and stories from the Shark Tank India pitch. Check it out! 00:00 - Journey of building Nuutjob 20:48 - Shark Tank India Experience --- Support this podcast: https://anchor.fm/secrets-of-storytellers/support

Maylee Todd spent a lot of time in VR throughout the pandemic, which led to ideas on a utopian technology. Her avatar, “Maloo,”  turned into a concept album with “Show Me” as a standout science fiction lullaby.  

On Cyrus Says, we have Mangalam Maloo, Assistant Editor & Anchor with CNBC-TV18. They talk about the freshly released Budget 2022. Also, finally Cyrus is in the studio!!! But why is he really there? Mangalam talks to us about him studying media, the multiple degrees, and what happened while he was on the way to his first interview. Further, they talk about whether any of the previous budgets have impressed Mangalam ever andwhy every budget has been eventful. Also, he tells us why has the Govt imposed a 30% tax on Crypto, whether that makes Crypto Legal and how is our govt trying to classify Cryptoo, and the what is the digital rupee. Further, they discuss if the Govt is not spending on health care, what's the insight about road construction and building bridges or are they digging roads just for fun. Tune in for this and much more. Follow Mangalam Maloo on LinkedIn, Twitter & Instagram: https://www.linkedin.com/in/mangalam-maloo-a83a3815/ https://twitter.com/blitzkreigm https://instagram.com/blitzkreigm Also, subscribe to Cyrus' YouTube channel: https://youtube.com/channel/UCHAb9jLYk0TwkWsCxom4q8A You can follow Antariksh on Instagram @antariksht: https://instagram.com/antariksht Do send in AMA questions for Cyrus by tweeting them to @cyrussaysin or e-mailing them at whatcyrussays@gmail.com Don't forget to follow Cyrus Broacha on Instagram @BoredBroacha (https://www.instagram.com/boredbroacha) In case you're late to the party and want to catch up on previous episodes of Cyrus Says you can do so at: www.ivmpodcasts.com/cyrussays You can listen to this show and other awesome shows on the new and improved IVM Podcasts App on Android: https://ivm.today/android or iOS: https://ivm.today/ios

I did three different remixes under my various aliases to give completely different vibes. Of course, all versions are available on all streaming platforms and all major music purchase sites including Beatport.com. https://www.beatport.com/release/come-over-here-2021/3366332

The One Take Show is honored to host Mr. Rajat Maloo. Rajat is a penultimate-year law student at NLSIU, Bangalore. Rajat ranked All India Rank 1 in CLAT 2017.

Welcome back to Overtaking Live where we talk the latest in car news, whats on in our local car scene and have mad quiz show with two followers! All the stories from this weeks show can be found linked below. Checkout all our New Products over at https://overtakinglane.com.au/shop https://www.facebook.com/groups/overtakinglane http://www.addictiveevents.com.au/?fbclid=IwAR085tbidQYaA4X0gkceIBWJMDi-xpF65HNU1CAAQD99WOfspbdDZFk5BqI https://www.facebook.com/KENDATIRES660DRAGRADIALSERIES/ https://dragillustrated.com/watch-john-hall-walks-away-from-brutal-pro-nitrous-crash-at-pdra-east-coast-nationals/ https://www.autoweek.com/racing/nhra/a35916148/why-nhra-funny-cars-called-funny-cars/ https://www.motoring.com.au/mint-holden-vl-walkinshaw-group-a-could-chalk-up-another-million-dollar-sale-129433/ https://www.caradvice.com.au/944528/mighty-car-mods-lotus-exige-sport-240-heads-to-auction/ https://www.abc.net.au/news/2021-04-15/tesla-invoice-scam-costs-two-australians-electric-car-deposit/13226126 https://practicalmotoring.com.au/car-news/matchbox-models-cars-going-carbon-neutral/ https://www.abc.net.au/news/2021-04-09/hire-rental-car-shortage-predicted-for-top-end-darwin-dry-season/100056688 https://www.themercury.com.au/motoring/motoring-news/the-surprising-link-between-cars-and-phones/news-story/02109f32b207f0cecea61653f177f56c https://www.carsales.com.au/editorial/details/custom-lexus-nx-4-6-set-to-change-your-mind-about-texting-and-driving-129398/ https://theindustryobserver.thebrag.com/spotify-hardware-in-vehicle-system-car-thing/ https://www.autocar.co.uk/car-news/new-cars/nissan-reveals-new-2022-gt-r-nismo-japan https://www.carsales.com.au/editorial/details/dominos-launch-autonomous-pizza-delivery-robot-vehicle-129396/

In this episode, Richard Berry, Matt Campbell and Byron Mathioudakis gather in cyberspace to talk about all things motoring, including:Potential classic cars you can get your hands on right now.The fresh metal we've been driving this week: the new Mercedes-Benz S Class, Ford Ranger FX4, Mazda CX-3 and an exciting new addition to Byron's garage...Plus MuskWatch: This week Elon gets continues his plan to control space while, as always, tweeting and memeing up a storm.You can get in touch with us on Facebook, Twitter (#CGPodcast) and Instagram, and let us know what your picks for future classic cars are by emailing comments@carsguide.com.au

In this episode, Mandy is joined by Mike Costello and William Stopford, with Anthony Crawford and Paul Maric chiming in to run through the latest in automotive news and what's happening at the CarExpert offices around Australia. This week in car news, the team talks about pricing for the new Mk8 Volkswagen Golf, the reveals of the redesigned Mitsubishi Outlander and Honda HR-V, and the arrival this year of new generations of Subaru WRX, BRZ and Levorg. Paul Maric dials in to share his experience with the $1 million HSV GTSR W1 Maloo ute, while Anthony Crawford talks about the Volkswagen Transporter T6.1 range. Where to find the CarExpert Podcast You can find the CarExpert Podcast on your favourite podcast platform. If in doubt, simply click on the RSS feed below, or follow the links to the Apple Podcasts or Google Podcasts applications to subscribe. CarExpert Podcast RSS Feed CarExpert Podcast on Apple Podcasts CarExpert Podcast on Google Podcasts CarExpert Podcast on Spotify CarExpert Podcast on Podbean

You asked.. We heard... We Delivered...From Indian Matchmaking Show on Netflix Pradhyuman Maloo joins Max!#indianmatchmaking #netflix #pradhyumanmaloo #MaxTucci #talkshow #podcast #podcastlife #awardwinningpodcast #tunein #radioshow #radio #India #love #matchmaker #matchmaking #foodie #nornament #simafrommumbai #communicatorawards #host #podcasthost #goodconversation #followforfollow #likesforlikes #12yearsonair #2theMax

Kurt Maloo ist die singende Hälfte der Band Double. Sein Welthit "The Captain Of Her Heart" von 1985 ist wahrscheinlich der international erfolgreichste Schweizer Song aller Zeiten.

In this episode, we speak with Khyati Maloo about her 7-day trip to Kerala!A few highlights from Khyati's trip:- Museums and art cafes in Cochin!- Periyar National Park and massages in Thekkady!- Sunset views in Kumarakom!We also talk about the culture of Kerala and how to go about exploring it!You can follow Khyati's adventures at www.khyatimaloo.in and on Instagram @khyatimaloo.Let us know what you thought of the episode! Give us a shout out on our Instagram @indiachalo. We'd love to know more about your experiences.See you next time!

Dr. Mohammed is the Founder and President of ManaGene considered one of the most innovative leaders in the emerging personalized medicine and lifestyle genomics space.   In August 2018, ManaGene merged with Youtrients (www.youtrients.me) to form a new company known as The DNA Company. The DNA Company represents the evolution of functional genomics and is focused solely on the optimization of human health and performance.   Dr. Mohammed is widely regarded as a pioneer in medical genomics and has been the recipient of multiple academic and industry awards. He is the holder of several patents in the general fields of molecular diagnostics and genomics research and is one of the most sought-after national and international conference speakers in the genre of personalized medical genomics. In this interview, Lisa and Dr. Mansoor dive deep into the power that lies in understanding your unique genes to change the outcome of your health.   Some take the fatalistic view that if you have a bad gene or combination of genes you are powerless against them so it's best not to know but nothing could be further from the truth. Understanding your genes through DNA testing is like getting the user manual to your body and learning how best to care and treat it. The granularity with which you can start to understand processes and how these affect you and how you impact these is astounding.   This s actionable knowledge that will help you make informed decisions regarding your health in such areas as your hormones, your cardiovascular risk factors, your methylation, your detoxification processes and even your mood and behavior, why for example some have a tendency to more problems around depression or PTSD than others.    Never before in the history of the human species have we had such deep insides into the way our intricate and complex bodies work.    This episode is set to blow your mind and the work of Dr. Mohammed and his team is set to change the future of the world's health. We have the opportunity for the first time to take control of our own destinies rather than falling victim to our genes through a lack of knowledge.   Once you start to see and understand the power of functional genomics you won't be able to go back to the way you understood yourself and your body before. Your level of self-acceptance and the ability to help yourself heal and be healthy and whole will be taken to a whole new level.   If you would like to get your hormones or your whole genomic profile tested you can find out more at www.thednacompany.com    We would like to thank our sponsors for this show:   www.vielight.com   Makers of Photobiomodulation devices that stimulate the brains mitocondria, the power houses of your brains energy, through infrared light to optimise your brain function.  To get 10% off your order use the code: TAMATI at www.vielight.com   For Lisa's New Book Relentless visit the website below to order https://shop.lisatamati.com/products/relentless   When extreme endurance athlete, Lisa Tamati, was confronted with the hardest challenge of her life, she fought with everything she had. Her beloved mother, Isobel, had suffered a huge aneurysm and stroke and was left with massive brain damage; she was like a baby in a woman's body. The prognosis was dire. There was very little hope that she would ever have any quality of life again. But Lisa is a fighter and stubborn. She absolutely refused to accept the words of the medical fraternity and instead decided that she was going to get her mother back or die trying.   For more information on Lisa Tamati's programs, books and documentaries please visit www.lisatamati.com    For Lisa's online run training coaching go to https://www.lisatamati.com/page/runningpage/ Join hundreds of athletes from all over the world and all levels smashing their running goals while staying healthy in mind and body.   Lisa's Epigenetics Testing Program https://www.lisatamati.com/page/epigenetics/ Get The User Manual For Your Specific Genes Which foods should you eat, and which ones should you avoid? When, and how often should you be eating? What type of exercise does your body respond best to, and when is it best to exercise? Discover the social interactions that will energize you and uncover your natural gifts and talents. These are just some of the questions you'll uncover the answers to in the Lisa Tamati Epigenetics Testing Program along with many others. There's a good reason why epigenetics is being hailed as the "future of personalized health", as it unlocks the user manual you'll wish you'd been born with!  No more guesswork. The program, developed by an international team of independent doctors, researchers, and technology programmers for over 15 years, uses a powerful epigenetics analysis platform informed by 100% evidenced-based medical research. The platform uses over 500 algorithms and 10,000 data points per user, to analyze body measurement and lifestyle stress data, that can all be captured from the comfort of your own home   For Lisa's Mental Toughness online course visit:  https://www.lisatamati.com/page/mindsetuniversity/ Developmental strength, emotional resilience, leadership skills and a never quit mentality - Helping you to reach your full potential and break free of those limiting beliefs.    For Lisa's free weekly Podcast "Pushing the Limits" subscribe on iTunes or your favorite podcast app or visit the website  https://www.lisatamati.com/page/podcast/     Transcript of the Podcast   Speaker 1: (00:01) Welcome to pushing the limits, the show that helps you reach your full potential with your host, Lisa Tamati, brought to you by Lisatamati.com Speaker 2: (00:13) Hey team. We're this week I have an absolutely superstar, the world's number one leading functional genomic specialists, Dr. Mohammed from Toronto and Canada. Dr Mansoor, Mohammed has two guests now. He is a scientist and entrepreneur in the field of genomics and is regarded as one of the most innovative leaders in the emerging personalized medicine and lifestyle genomic space. Dr Mohammed is a PhD and president and scientific officer at the DNA company and is really considered to be a pioneer medical genomics. He's a classically trained molecular immunologist who has received academic and industry awards, published numerous papers and holds patients in the general fields of molecular diagnostics in genomics. Now functional genomics is about understanding the DNA and how it behaves in every definition and this Dr. Mentor was very different than many of the other DNA companies that I've looked at recently and that he doesn't just look at the single litters, if you like, of the DNA, but it looks in combinations of genes. Speaker 2: (01:22) And how they're playing out. And this makes him very, very different. This, he sees DNA like a language rather than a vocabulary and language that has grammar, sentence structure, Syntex and nuances. And you've got to be able to read genetic structure at the holistic level. Now I'm super excited about document's all his work and I'm studying functional genomics at the moment and it is the next level in personalized health. I'm really, really excited to bring this interview to you. It's taken me months to get documents or on this podcast and I'm hoping later on the year to get Dr. Mansoor Down to New Zealand for a lecture tour to speak to functional medicine practitioners down here as well as the public. So if you'd like to know more about that, please reach out to me and let me know. I'm just like to remind you before I hand over to Dr. Mansoor that my book launch is happening just next week over the time of this recording is the 6th of March and on the 11th of March. Speaker 2: (02:26) So by the time this recording actually comes out, my book will be live. It's called relentless and it tells the story of bringing my mum back after a major aneurism myth. You're fighting for a life and lift her in and basically not much over a vegetative state. Massive brain damage at the age of 64 and what I did to beat all the odds and bringing my mum back to health, all of the CRPS I used, the protocols, the attitude, the mindset, the obstacles that we had to overcome, the problems that I've discovered in our medical system in on it goes. So this book is really, I'm, I'm so pleased to be able to bring it out. It's taken me two years to get this together and to bring it to the public, but I really want to pay it forward and I want to help thousands and thousands of other people facing difficult challenges to take them are hit on with the right mindset to overcome great obstacles. Speaker 2: (03:18) So if you'd like to check that out, we can head over to my website. I have Lisatamati.com Hit the shop button and you'll see all of my books there and my jewelry collections. But make sure you check out the neatness. It's really going to be worth a read for anyone who has major medical problems at the moment. Or of course anyone who has a stroke aneurysm Alzheimer's dementia, and wants to know about brain rehabilitation or optimizing your brain function and who isn't interested in that as well as the whole mental attitude and mindset that it takes to do all this. So without further ado, over to Dr. Mansoor Mohammed. Well, hi everybody. Lisa Tamati here at pushing the limits. It's fantastic to have you back again. Now I am just grinning from ear to ear. I can't stop smiling because I've been waiting for this interview for weeks. I have a very, very special guest, Dr. Mansoor Mohammed, all the way from Toronto in Canada. Dr. Mansoor How are you going? Speaker 3: (04:17) I am great, Lisa. And likewise, it's been something that I've been looking forward to, to the audience. Please forgive me. I'm a little bit sleepy from Jeff blog from last night, but Lisa has been pumping me up and so we're going to have some fun of this Speaker 2: (04:31) Now. I know what it's like when you're a little bit jetlagged and you have a main very much in demand. So I'm just so excited to have a little bit of time with you now. Dr Mansoor, I do the whole introduction on a separate recording, but dr Mansoor, can you give us a little bit of background about your what you did your PhD in your, your, a little bit of a brief history of your back. Speaker 3: (04:55) Sure. genes. Genetics has always have always been my love. The study of how this operating manual, just just thinking, just, just dialing it back and thinking that the human being, we've got this operating manual that by every definition of the word it behaves like an operating manual. And to think that it's there and to think that one date might be accessible and that we could read this and we could read it intelligently and just simply understand myself much less, much less. Anyone else has always been my love. And so I started, my PhD is in applied molecular genetics and immunology. So I was looking at the genetics of the immune system. I was very, very fortunate to have an awesome mentor. She was then the chair of molecular biology at UCLA invited me to UCLA. So I had an awesome couple of postdocs there where I got deeper and deeper involved in eugenics. Speaker 3: (05:47) But a real pivotal point happened when I was done, invited to come to Baylor college of medicine and Houston, Texas. And it was that heavy time just about the human genome project, its, you know, sort of pinnacle. And I was asked because of the work that I had been doing with UCLA to come over to Baylor and start a company, the goal of this company was to begin looking at multiplex genomics. In other words, to really do the, you know, the barrage searches into the human genome. Not one gene at a time, but looking at the entire genome in pathway type manners. Now initially we applied this knowledge to cancers. We apply this knowledge to developmental disorders syndromes, Prader, Willi syndrome, autistic spectrum disorders and so on and so forth. And about 15 years ago, after many years of doing what I call disease genomics, looking at the operating manual, looking at when the operating money was broken out of what happens from a disease perspective. Speaker 3: (06:45) Then I sort of thought, okay, well that was fun. That was good. That was, but why should I not look at the operating manual? But nothing is purportedly broken, but just the operating manual. So then still we can tell presumptively healthy individuals how to stay healthy or how to get over the type of chronic illnesses. So this is what I've been doing for the last 15 years, studying, researching and applying the knowledge of the human genomic operating manual. So we've been, we can just simply understand it. How does the body work, which clearly there's an individuality to that, obviously. I mean, we are human beings. We all, our cells, our organs, our bodies, all have to accomplish the same jobs that we do. These jobs with nuance differences, some of us less optimal, more optimal, more efficient, less efficient. And when we can zone into that, when we can read this operating manual from that perspective, really Lisa miracles happened with the sort of insights that you get, the nuances that you can tease out. It really has transformed the clinicians. We train the patients, we work with the transforms, it empowers the individual to understand how their body works and what they might do to obtain that optimal health. Speaker 2: (07:59) This is, and this is a super exciting and I can feel your passion coming through despite the jet lag for this area and it's now mind you, passion is of the last maybe two months or six weeks or however long it is now that I've been diving into this world and just going, Oh my gosh. Oh my gosh, this is just, this is just the next level and the information that I've been searching for to try to understand because everything seems so generic. And this a personalized house and yeah, doctor man saw you the president and founder of the DNA company, which is offering direct to public and in conjunction with conditions. A couple of reports. So our full genomic report in a hormone report and I want to tease apart a little bit today, why should people even consider having a look at these, the sort of testing what benefits they can get out of it. Speaker 2: (08:58) And I'd like to also tease a little bit about looking at other, like I've, I've looked at a lot of gene companies and that do gene DNA testing. And you had an analogy on a Bulletproof radio that I heard you on the same show who's amazing Dave and his work that was about the most people are looking at it DNA as a vocabulary and not a language. And that just seems them light bulb up in my head where I realized, okay, so it's not the siloed genes looking at them individually, but looking at cascades and pathways and combinations of genes as we are then interpretation has been missing today. Speaker 3: (09:43) Oh, 100%. So I always say, you know, Lisa, anyone that is in the data business, regardless of whatever data you're collecting, data is really quite dumb. Data in and of itself doesn't mean anything unless you know what to ask of the data unless you know how to triage, how to approach the data. So when we use the analogy as DNA, the operating manual, the genome, it really meets all the classifications and descriptions of a language. Thus far we've been looking at DNA and genetics from a language perspective purely as a vocabulary exercise. The more words we know, the better we presume to think we know the language. And as much as that is important as per the analogy that I drew with on Dave, show a person simply knowing more vocabulary by no means mean they understand the language. And so when it comes to DNA, when it comes to genetics, when it comes to how this awesome operating manual, the architecture of it, it's not just about vocabulary, it's not just about the individual genes. Speaker 3: (10:51) So here are the two layers implicit in your question that we do a bit differently and why we need to do that differently and why it's important that it's done this way. The first is this. When you're looking at the DNA, if the person are either genetic makeup, the vast, vast majority of companies right now, they're looking at things called snips, single nucleotide polymorphisms. In other words, they're looking at places which is absolutely important. They're looking at spelling variations in this operating manual. And of course these spelling variations, these single nucleotide polymorphisms will impart to you mean Jane, Paul, Peter, the same cellular job that we all want to do. These spelling differences can impact the efficiency with which we do that job and that is important to know, but while we're at that point of spelling, you see per any language, if I wrote a paragraph, I might have spelling errors in that paragraph, but there are examples where I may have inadvertently deleted a sentence or deleted a couple of sentences in that paragraph. Speaker 3: (12:00) Now, if the analogy here is that the gene is the paragraph, so your operating manual are these 23 volumes. Think of it. Think of a 23 volume and psychopathic set these awesome, huge volumes. Now we're going to inherit two of these 23 volumes. One from mom, one from dad, and these volumes are properly arranged and when we open up any page, let's say we go to volume three from mum volume three from dad, we open up page four on each of those volumes and we look at paragraph five page four, volume three we, I see the same paragraph. We're going to see the same information from dad's gene paragraphs of genes and mom's gene. We're going to see the same information, but when we look really carefully, when we look at those paragraphs, really collect carefully, we might find that there's some spelling differences. Those are the snips. Speaker 3: (12:57) We may also find that on either dad or mom's paragraph, a sentence was missing and I just taught this over the weekend. So I was in the auditorium and I said, okay, here's an instruction that was waiting for me coming to this auditorium to give this lecture, Dr Mansoor, go to auditorium B and to the left door approach to podium from the right side, press the enter button, begin your lecture. That's an instruction. That's a paragraph. That's an instruction and that's the equivalent of a gene. Now in that paragraph they make has been a few spelling errors or changes that may have confused me a little as to what the instructions are. But when I look at it carefully, I could sort of still figure it out. Okay. But if in that paragraph, the sentence that says go to auditorium B was missing at, of course there are multiple auditoriums, all of the other parts of the instructions are there. Speaker 3: (14:03) But I can really be confused as to what is the ultimate thing that I'm supposed to do. It's called an indel. So in our genes, not only do our genes have slips, many important genes actually have places within them that I'm missing. So until we test for those type of changes, we're by no means getting the full picture of what is happening. The third thing is this, not only do we have slips, not only do we have in Dells, there are occasions where the entire gene is missing is show I'm supposed to show up. I got to the hotel where the conferences are and the instruction just telling me what it's just not even there. So here I'm in the lobby going, I don't know what I'm supposed to do. This example is a genetic phenomenon keeping the analogy, this is called this C and V copy number variation. Speaker 3: (15:03) We see because we were supposed to have two copies of that. Paragraph five page four, volume three. Sometimes believe it or not, when we go to page four we've opened up mum's volume three dad's volume three. There they are. We're going to read both of the instructions cause that's what yourself has to do at any given moment. When there's a job to be done, your cell goes and pulls the volume that has that instruction, takes down a mum's copy, takes down, dad's copy, opens up and reads the instruction. Now in the case of a CMV copying of the variation, we can open up mum's volume three page four there is paragraph one, paragraph two, paragraph three paragraph four paragraph six. Oops, wait a minute. Where's part of our five? It's gone. There's part of four. There's part of six. I look over a dad. He's got all of the paragraphs or vice versa. Speaker 3: (16:02) Sometimes Lisa, both paragraph fives are gone. Okay. So the point of the first answer to your question, why we do things a bit differently is we're not just in the business of collecting data for data's sake. We're collecting data. Are you were doing gene testing to understand a process. When we designed genetic tests, we don't begin with genes. We begin in a whiteboard saying, what is the thing in the human body that we want to study? What is the thing that we want to study? Genetics, just good old fashioned medical textbook, human physiology. Do we want to study the way the newer chemicals are produced and bonding and response? Do we want to study how the human body makes sex hormones? Something we should talk about when it comes to human performance. So how does the male and female body makes progesterones androgens Astros? And then we mapped that out. Speaker 3: (16:56) Forget genetics, which is not about how does the human body do that? No, of course, if the human body's having to do something, then it means there are genetic instructions for that film. So only when we map out the cellular, the cellular biology, the cascade, only when we met that out, then we come in and we pencil it. This gene is responsible for here. This gene is responsible for there such that at the end of the exercise, we've got a genetic test that already tells a story. The result from that genetic test is telling you the entire cascade. Step one, step two. We look at each of those genes that are telling us the story and we ask are these snips that are important? Are there entails that are important? Are the CNVs that are important because all three make a wow. And so the first part to the answer to your question is if you've been looking at genetic tests that are only reporting snips, you are dramatically limiting the variations that you and I and every other person have within our genome. So you're missing the nuances that are in your language to clarify the job to be done. Does that make sense? Speaker 2: (18:16) Absolutely. So that actually puts them together in my head because I've been starting this, I don't know, like for example, the GSTT one gene and the detox and antioxidant pathway, one of those types of genes that can be completely done. Speaker 3: (18:31) Completely. Totally said, absolutely. And of course it belongs to super family. So there are multiple G S T genes, but two minutes on that. If you're going to design the human body and you're going to say, listen, one day we're going to make this thing called human being and we're going to put him or her in this wonderful world, but mind you, he or she is going to have to deal with some toxic insults, both from without and from within. Where would you, and you know that, where would you put your detox defenses? Well, they're about four places. If you're an intelligent designer, you would put your detox, different defenses at least in four places. You would say, how and where do things get into the human body, dermal skin, the nose, nasal Bronxville lung, the GI track. Okay. So those are how things get it. Speaker 3: (19:23) And unsurprisingly you would want to make sure your detox genes and the things that you'd want to make sure there's super active in those places. And then you, you'd also say, well look, at the end of the day, things are always going to get past borders inside of the body, their waste products. So then I'm also going to put a detox organ. The liver, when we go to the human body, this is where we find these detox genes expressing themselves. And each of the GST is have sub specialties. Some of them are more important in the nasal bronchial track, some of them more important in the GI track and so on and so forth. So when you know the story that you want to read about the body, you know how to read the manual and interpret, is the GST T one gene deleted or not? This is a massive implication to the human body. Speaker 3: (20:16) Can you imagine the GSTT one gene is one of, if not the most important bio transforming antioxidizing enzymes in the body per its name and its gene and its enzyme. And if a person doesn't have it, literally it's not in mere manual. The GSTT one gene is on volume 22 and if that paragraph you have not inherited it from either mum or dad, you are missing an enzyme in your body. That is one of the most important detox. Now doesn't mean that you're not compatible with life, but it most certainly means you could not be the person who says, well you know what do you have a metals mean after all they're not that bad. Oh you know what, my uncle smoked until he was 80 years old. I'm going to smoke as well. Well you can't compare yourself to that person cause you don't have one of the most awesome detox genes. Speaker 2: (21:13) You don't have a good defense mechanism. And so like the detox is actually the first port of call before the immune system even does this job. So I'm, I'm excited to get my tests back cause I haven't gotten gotten through the reports yet. I'm, I'm suspecting that I have a problem in my GC jeans because I'm a very young age. For example, I've been the next medic as a, as a severe asthmatic, as a child, and I'm very hypersensitive to smells and anything. So I'm like a Canary one C one, which is theta. Yes, Speaker 3: (21:54) Very important in the liver. Key one PI GSTP one is the one that's really important in your nasal bronchiolar lung cavity. Individuals with a suboptimal P one are at extreme risk of early ectopic asthmas. They're the ones that if they go into the shopping mall, you know, the perfume resection, they've got to avoid the perfume resection. Right? Those are the GSTP ones. Speaker 2: (22:21) Wow. I'm obey. Fascinating to see if that's what comes back. And so if you want it deleted into them, we'll get onto hormones next because I really want to dive into there, but just to, to to look at the GST genes. If you don't have, you either have only one inherited GST, one gene, your mother or your father and you're missing the other ones or you're missing both altogether, are you more likely to have you're more likely to have toxins coming in that you can't deal with as well. And then your immune system is this way or auto-immune or part of the Speaker 3: (22:57) Brilliant, brilliant question. Just before we answer that, I had mentioned there were two layers to differentiate yourself, so just so that we close the chapter on what we do differently. So I'm going to come back and, and so now we will take it forward. We just mentioned that there you have to be mindful of the three different layers of variations, snips in Dalles with pieces of the genome missing and CNVs where the whole gene may be missing. The other quick differentiator, bringing back the analogy of a language, bringing back the story of the human body, it's this, and I told the audience this, there was an audience of clinicians in Phoenix this weekend. I said, have you ever read a really good, you know, suspense novel and not suspense novel, the novel that the author's painting the character and you're thinking he's the bad guy, you know, and he's falling around the heroin and he knows he looks a bit shady. Speaker 3: (23:51) And then until or unless you've read the entire book, you only find out that he was a protector or he was something. He was a guardian and words. He wasn't about that guy. Now what the heck does this have to do with genes? The second player, when we mentioned that we do things differently, we said that DNA is really a language by all of its definitions, with its nuances is this, there are many genes, Lisa, where if you were to look at that gene as a standalone and if you was to look at the genotype of that gene, in other words, what version do you have? You think you have either the best version or the worst version depending, and you may think you have the best version for example, but it is not until you look at a completely independent gene that has nothing to do with this gene, that the version of that independent gene wow colors, whether your actual optimal version of gene a will stay optimal or not. Speaker 3: (24:52) Or conversely, whether you thought you had the suboptimal version of a bad guy, you read the full story, something else tells you what you fought was the bad guy was not the bad guy. Wow. And this is what it's called at peace basis. You see we're all concerned about epigenetics, which is important. FP genetics. How are we reading? Are we actually going to read that paragraph on the page or are we not going to read? That's at the genetics, but nobody's talking about epi. Stacy, this is Stacy. This is often, we've read the page after we've read the paragraph. We cannot yet make a conclusion until we read 10 pages later, 15 pages later, something there. We'll bring it to life. We'll color what we read on page three. Speaker 2: (25:48) Yeah, so, so for example, if you're, if you're looking at a specific gene and it has an, that is say the faster for the sip, 79A1 gene and the hormone a kiss guide. If it's a fast one that's not in and of itself a good or a bad thing. It depends on the other things. It depends on the, so that's what you're meaning. So one of Speaker 3: (26:14) The best examples of that is this, the BDNF gene, the BDNF gene, brain derived neurotrophic factor. What are the most important genes in the brain? Well, in the whole human genome that tells the brain how to secrete this awesome thing that heals the brain. You and I were having a conversation about a loved one, so that loved ones B, D and F was going to be hugely important. And how that loved one recuperated from the challenge that she had met BDNF. Now the beating of gene has an important variation. A snip this time, which is either a G version or a version. Okay. TheG version, Jews and George as in guanine is the optimal version of BDNF, the optimal version. So if you're a GG blessed, that's good. You are naturally predisposed. You have the in Harrods, the innate ability to make more BDNF. Speaker 3: (27:13) And let me tell you that's a good thing. Any which way you slice it. Wow. An independent gene, the TPH to gene the trip to five hydroxylase gene to TPH, two gene, which is involved in how the body deals with serotonin. K two has a sip. It comes in a G version and a T version G as in George T as in Thomas. The G version is considered optimal but hold on. If you happen to be GG fatigue, pH two and GG for BDNF ostensively both those genotypes for each affair genes are optimal, but if you were GG for both, it creates a haplotype. It creates a combination that is an act risk combination and it is, it is the negative combination. It is the, it is the deleterious combination when it comes to certain aspects of human behavior. These individuals, when you're GGGG, they exhibit poor inhibition of negative emotional stimuli. Speaker 3: (28:28) In other words, when something negatively emotionally affects them, their ability to kinship, the ability to say, you know what, I'm not going to focus. I'm not going to hamster wheel constantly play that over and over over again. They haven't, they have a hard time giving up that when something gets under their skin. So to speak emotionally, they have a really hard time getting over it so they have a strong imprint. The memory imprint, very strong EMI, emotional memory imprint and of course the stronger you EMI emotionally memory imprints, the easier you emotional memory recall EMR is because the deeper something is imprinted then the smallest cue. You have a love, you have a partner and you know you love each other to bits, but like human beings, you're going to have your ups and downs. I mean it's where human beings after all, and on one particular evening you were both getting on each other's nerves and she was wearing that beautiful red dress and that was the evening that you both said things you shouldn't have said and it hurts the person who has this phenomena. Speaker 3: (29:36) Whenever he sees his wife, would that red dress down the road, everything's perfect. You, you're going up for a birthday party, you're both happy, it rises back up. He remembers that evening more than he should. It brings back to the surface and vice versa. This is that Paul, inhibition of negative emotional stimuli that lead to profound memory imprinting and therefore profound memory. Recall. The point of all of this and the reason I mentioned this is, and we're going to come back to the GSTT one, was to clarify, you see Lisa, it's not just about even the type of things you're looking for. What matters is the interpretation we sell the combination, we are reading the manual, not just flipping, picking words out. Speaker 2: (30:24) This is we have a calmer is well we are the, the apostrophes are this is someone that is what they would be more prone to PTSD Speaker 3: (30:36) 100 that's the point actually and that is further exacerbated based on the no adrenergic pathway which dramatically increases the risk of PTSD. It is exacerbated based on how quickly they are removing their dopamine and noradrenaline via content. So what happens is you begin to pixelate a picture and you've got a low resolution picture and then the more intelligence information you put in, you start to increase the resolution of that picture. You start to get a clearer picture of the person that you're looking at. But to do so, you've got to know where to pick slate. If I'm trying to get a better look at what Lisa's face look like, I don't really be pixelating your toes. I need to pick slick your face and this, this ability to read intelligently. Lisa, I stress intelligently. Riyadh, human genome. Yeah, that's what we do. We do Speaker 2: (31:35) That is absolutely insane. And they've vacations because yeah, I would have seen, Oh, you've got a G G G is good, but I've just understood that nuance, that combination of things. And now I can't wait to get my reports and my family reports so I could because this helps us also understand like the speed in which you are dopamine is processed and gotten rid off or the speed of which we're saratonin tone and all of these things have a fixed on your personality and that we're not 100% to blame for some of our differences. Speaker 3: (32:12) Oh gosh, no. Gosh, no. In fact, what this needs to do on the one hand, it creates the empathy of appreciating, look, this is how some of this is their predisposition. Now, on the other hand, it is not to create a sense of fatalism. While that's the way I am, I know I have found and I have done. The only thing that I've done, probably somewhat unique and special Lisa, is I have reviewed thousands upon thousands of profiles. In terms of my in the world, most of my peers that work at the level I do would say Dr. Mansoor Probably reviewed the most genomic profiles in the world. I don't know if that's true or not, but I certainly have reviewed several thousand meaning meeting the patient, speaking with their doctor, looking at their health profiles and looking at underlining genetic phenomena to see if we can understand what's going on. Speaker 3: (33:00) You know what I found, at least as a fellow, when you empower a person to understand a predisposition, you, you might think that leads to fatalism, but when you explain the functional reality, it actually does the opposite. It gives the person a sense of ownership and then they can finally say, you know, I have dumped with my entire life, I've been this way and I just, I didn't even know why it was that way. Now that I can even understand what's going on, it gives me some closure. Yes, but it now gives me something to appreciate. I can, I can envision how this is working, how my emotions are working. I can now go, you know what? As soon as I see that stimulus that would have got me on that slippery slope, I'm going to stop. I'm not going to go down that slippery slope because I know if I do, there's no coming back for the next two weeks. Speaker 3: (33:52) So what we've found is that this crew all around it just creates empowerment. Which brings me now to the question that you asked about GSTT one and you are, your connections are on point, Lisa, the connection between the detox mechanism of the body. Here's the threefold, and of course it's a bit more complicated, but it's also remarkable. You can take complex systems, break them down to building blocks and keep the acuity. So there are three building blocks we need to look at when we connect detoxification pathways in the body and the immune system. And the, the only thing missing is the inflammatory system. So the triangulation between toxins and immune responses goes like this. The human body's insulted with whatever. It's insulted with the intentional, the unintentional of our daily lives, those toxins enter the body or they try to enter the body. Step number one, how individually efficient is that person at negating bio transforming, neutralizing those toxins either before they can enter the body, such as in the mucosa of the lung, the alveoli lumen, the the lining of the lung, such as the GI mucosa and so on. Speaker 3: (35:16) And so what can we, can we neutralize it so the toxin doesn't even get into the bloodstream? And of course to the degree that it gets into the bloodstream, can we live a hepatic re detoxified so that at least it does not by you accumulate in the body so that at least it does not reach levels that are unsafe. First step number one now too, there are genes, there are whole gene families, their whole cellular processes, GSTs, glutathione, ionization, UGI, Ts, glucuronidation, methylation, self, phonation and acetylation. These are the major enzymatic steps linked to genetic genes that are responsible for bio transforming neutralizing things in our body, okay? So what we need to do is we say, what is the lifestyle environmental context of the person? What are they getting exposed to? I'll be living in a home that has written with mold, are they living and so on and so forth. Speaker 3: (36:17) Okay, step number one, step number two, how good are they at individually neutralizing those toxins so as to not bio accumulate them to the degree that those, whatever. The answer to that question is we're going to have an individualization and with some individuals are better at getting rid of toxins and others are not. If a person is not genetically, innately efficient, optimal at getting rid of their toxins, then what happens? Well, what do toxins do? Toxins cause cellular inflammation, okay? And they cause inflammation via any number of methodologies. They can inflame cell surface receptors, they can get into the cell and create overproduction of oxidants as they can hamper the energy modules, the mitochondria. That's one of the places you'd never want toxins getting to. And of course they can get into the nuclear eye. They can get into the libraries of the operating manual and they can start to change gene expression. Speaker 3: (37:23) So toxins do all of these things. Ultimately, you see Lisa 15 not even 15 years ago, 10 years ago, if you told that a medical conference, there's this concept of inflammation. You'd have a lot of professionals. Well, come on, you gotta be more specific than that. We actually now know that there is a phenomena called chronic inflammation, and regardless of what stimulated that inflammation, bat bacterial toxin B, it's an inorganic chemical. It be it a physical inflammation. It does not matter the way the sun looks, the way the cell begins to behave when it has been insulted with toxins, with exposures, remarkably is the same regardless of the stimulus. Because chronic inflammation has hallmarks that are similar regardless of the stimulus. Now at that juncture, when the cell is inflamed, when the machinery in the cell isn't doing the job that it's meant to do properly, that cell now starts to be like this pulsing red thing just by analogy. Speaker 3: (38:35) In other words, the body is looking at it going, something's happening in there. It's not behaving the way it should. Okay, so now we're going to have two steps. The body now has an anti inflammatory set of steps to quiet us, to bring the cell back into line cause they Whoa, Whoa, hold on. You're starting to misbehave. There's too much inflammation. This is where it's selling the process known as methylation comes in. Cellular methylation can be viewed. It's a detox reaction by the way, but it is a cellular cascade that is radically responsible for bringing your soul from that humming, inflamed, you know, ticking bomb type of modality back down to acquire essence behavior. That's cellular methylation. Now, to the degree that you're able to do that, because suddenly methylation is a multigene cascade, multiple places where things could be not as optimal as we would like. Speaker 3: (39:36) So to the degree that we then triage, we stratify the patients based on their detox potential. We then stratify them based on their anti inflammatory potential. Now, to the degree that we are not quite yessing that chronic inflammation, this is where the immune system can be activated. Immune system was meant to be activated in acute episodes, not chronic episodes. The more you ask the cell to produce antibodies, IgG, IGA is IGMs, particularly IgGs. The more you keep telling that the body pump out IgG, something's not working right, something is there, which is why chronic infections are now very well understood to be linked to autoimmune diseases. The infection did, did not go away, constantly demanded of the body to produce antibodies. And somewhere along the line those antibodies begin to forget what was the bacteria or what and what was the self. And now we just start shooting friend and foe alike. Wow. This is the triangulation that has become now a focal point of so many diseases. Some diseases being more relevant to the whole, you know, things like lying disease. Do you guys have lung disease down in New Zealand? Speaker 2: (41:05) I think, yes, we do. And I think you know we have a massive problem with like thyroid, Hashimoto's sort of autoimmune diseases, crones, IVs. So this is, this is where the body is actually going in overdrive. So the, the original detox genes haven't been able to do their job because combination. Speaker 3: (41:26) There's that one. Exactly. There's inflammation. Yup. Speaker 2: (41:33) Yes. Speaker 3: (41:33) Methylation didn't do the job that was supposed to do and now we're triggering. So there are meta-analyses meta-analyses that show the deletion of the GSTT one gene or overall poor Ghouta finalization has been strongly linked with ulcerative colitis, Crohn's disease, IBD, strongly linked with ectopic asthma, particularly GSTP one in early childhood asthma. Then of course, if you, if you double down on poor math on poor detoxification with poor methylation, you really start seeing Speaker 2: (42:10) Clinical outcome. Yes. Yeah. So, so if we then we, we, we find out all this about ourselves. We find out we've got either the good or the bad and the ugly. And these combinations are not ideal. Then how, you know, we've got this information now, now we want to know what the heck do I do about this? I can't change my DNA. Of course, all things that these reports that your company does, for example, where it can actually lead to some successful outcomes. Obviously avoiding cigarette smoke or exhaust folk tunes and things your GPS deleted. But, but beyond that, nutraceuticals, new nutrients what can be done to help people. Speaker 3: (42:52) So it starts with, so the first thing I would have to say is we take our reports only so far. So the actual report, we take it to the point of explanation of what's happening. And there are certain recommendations, but the real magic must still come from a trained population, you know? So what, so what we do is through also training a certain class of healthcare providers. We might call them the, the new modern day biohackers. The healthcare providers who are really sniff, they're no longer just, you know, pill pushers. They're looking. So I just wanted to clarify. We take the reports, we explain the systems, we explain what's happening, but we also have to be careful so that people aren't jumping to conclusions and self-treating based. So you still want to have someone who understands the bigger picture. And by the way, that's the second part of what our company does. Speaker 3: (43:47) As per my travel schedule, I'm constantly traveling, teaching people, teaching auditoriums full of doctors who are now saying, listen, if I keep practicing medicine the way that I'm practicing, I'm just dealing with a disease population. I'm not healing people. Okay, so with that minor clarification, now we come to, let me paint a picture, paints a thousand words not to be, you know, blahzay here's what I like people to picture and here's what you would want to picture for yourself. Lisa. Picture slide. Okay, so there's a slide your screen, okay, and a circle. And then picture a circle on that screen somewhere on your screen. There's a circle. Now because you're a human being, your circle is going be on the screen. In other words, this is the screen of all human beings and your circle, you, your circle is somewhere on the screen or what does the circle represents? It represents your genetic makeup, which represents a part of your genetic makeup for whatever biochemical process we were studying. So this circle is Lisa's genomic pathway. Okay. Speaker 3: (44:56) I want you to then think of an equilateral triangle that equal three sided triangle that just perfectly encompasses your circle just perfectly. Your circle is perfectly encompassed just right in that triangle. And the emphases of this triangle are labeled environment, lifestyle and nutrition. Yes. What we're learning and what we're recognizing more and more is other than extreme cases, other than extreme cases, and there are mind you extreme cases where a particular genetic combination was really just a real doozy. And in other words, we're going to see some, you know, with the best of efforts, we're going to see some probably deleterious outcomes. Fair enough. But other than those extreme cases, for the vast majority of us, the spite, any inefficiencies we might have if we find the right triangulation of lifestyle, nutrition and lifestyle, nutrition and environment. If we could figure that out and it perfectly matches, I would circle. Speaker 3: (46:08) This is optimal health. So image, the image of optimal health is when you can find your genomic makeup, your circle for whatever you're studying and contextualize it perfectly within the right for you. For Lisa Laughlin, sir, not for Joanne Felisa. What is leases? Optimal lifestyle, nutrition and environment. Now the problem is, Lisa, when we begin working with a patient, obviously and clinicians with their patients, the vast majority of individuals, they do not know their circle. They don't know what's the economic influence. So they don't, and if you don't know your circle, your triangulation, choices of lifestyle choices, nutrition choices, and environmental choices offers skewed and they are not synergistic with your circle. So first objective of this, did you get that picture? Do you know when people say, well, it depends on your genes, your genes. It depends on how you're using your body. If you are, if you took, if you took five identical individuals, they were, you know, quintuplets identical, contemplative. Speaker 3: (47:27) If such a thing exists in today, the same genes and you give those five people at 35 years old, the exact diet. But if those five, one of them was an ultra marathon runner and extreme sports enthusiasts, the other was a couch potato, I don't know, doing whatever the other was a, you know, an accountant who had a nine to five job. We can exercise worrier, but from Monday through Friday really just goes to work, comes home, eats, goes to that and so on and so forth. Even with the same jeans, you can put the nutrition and an obviously not expect the same outcome because they got to know the genomic legacy. You've got to know what is the lifestyle context, what is the nutritional context, what is the environment or context? If one of the things quintuplets moved from your gorgeous country and move to massive metropolis with, you know, air quality, that breathing for one day is the equivalent of smoking a pack of cigarettes in your beautiful country. Speaker 3: (48:36) He or she may have gotten away with a GSTT one or GSTP, one suboptimal ability. He's living in those, you know, that wonderful country views. He's practicing otherwise good, not eating foods with pesticides and herbicides and so on and so forth. And he was going about life actually, not really realizing there was any suboptimal ability until one day his job took him to a big metropolis somewhere. He lost track of the quality of his foods. He's just so busy. He's day in, day out breathing the equivalent of a pack of cigarettes and then six months into this, all things ELLs as equal, his jeans are equal, but he now starts to show symptomologies that he would never have had any different environment and a nice clean environment. Right? So this triangulation is so important. Now coming back to the specifics, once we understand the pathways, we begin first with the dose. Speaker 3: (49:31) It may seem simple, but it actually enters Lisa into, it's not just about the obvious things that you might imagine. I give the example, Lisa, and by the way, it's relevant to the GSTT one gene. Now, juice, TT. Let's focus on the T one. It's the big sister in the glue, the fine fabric. So GSTT one no, it's what's called a phase two detox pathway. Phase two detox. Because when it talks and enters the human body, we typically go through two steps. We take toxin a, we converted into an intermediate B. Yup. We take B further, convert that to C. C is what leaves the body, the B to C part of the transformation. That's where the GSTs come in. The a to B. This is where your cytochrome P four 50s come in. That's the phase one. Bio transforming enzymes. Now if I were to ask you something, when you say fiber to say, would it be a good practice for person to start drinking a nice cup of green juice? Speaker 3: (50:38) You know, like some juice, juice, broccoli and some maybe put a little bit of a baby spinach in there. A bit of ginger, maybe some cute, cute curcumin at the end of it. Would that be a really healthy drink? Yes. Something I do every day. Beautiful, beautiful. And it is healthy generally speaking. So now someone puts a blog together giving this recipe of something that's ostensibly so healthy and there's this mechanic who works in a shop all day with fuse and so on and so forth. He read this blog, she read this blog and she decides that before she goes to work, she's going to have this beautiful juice. This green juice that they read was so healthy and it was a detox juice and they feel good about themselves. Hold on, hold on. Many of the ingredients and not green juice. Many of the ingredients in that green shoes turn on certain phase one sip four 50 enzymes so as to accelerate the conversion of a to B. Speaker 3: (51:54) Now some of the toxins a that this mechanic was facing in her shop, in the, in the, in the mechanic shop that she was working at, when she converts a to B, we know that the B, the intermediate is truly more toxic than wow. And by the way, she did not know she was a GST one deleted individual. Oh, so what did we do to this young woman? We encourage the things that is that we're getting into her body. When she drove that beautiful healthy green juice, she more rapidly converted her A's into B and then ups B's and to CS very well. Wow. Even something that would ostensibly be really healthy by normal standards. Do you see that's a healthy nutrition on the triangle, but we did not ask what was the environment on the triangle and so now we have skewed her triangle away because her genetics circle, she does not have the GSTT one. Do you get that picture? This is a little bit frightening for people who are listening to this or who might be going well, what's the point being? Speaker 3: (53:16) This is weird. The reports have the super value, isn't it? That's the point. It's, it's actually not discouraging. It's, it's finally, and this is all gold. It's finally meant to unravel those nuances that there is such a thing. Have you been? How many of us, you know, we do something that 20 or the coworkers swore was the best thing since sliced bread and then we tried it and not only did it not work, we actually felt like crap or less healthy, and we, we're all aware of this until it's what is it led? It's led for most of us to become numb. We're just kind of get to that point where we're like, well, I don't know what's right for me or run for me. Plus today it says one thing tomorrow it says another thing. So creating some sanity from this confusion is what this goal is about and it can be done. Speaker 3: (54:11) Lisa, when you take your time to read things, intelligent meals, explain things. That's why we've got these epiphany moments that constantly, I like my consults with patients because I feed off of the energy. When a patient just, you see that epiphany admission and they light up and they go, Oh, that's why this hasn't been working with. That's why that was better for me. That's why I took methyl B12 because everyone's telling me methyl B12 is the best version. But every time I take methyl B is it just in my head. I get a headache every time I take micro B12 I get a, and then I go, no, actually I got one too. I can't take methyl before. That's an actual thing. I can't take methyl B12 because my methylation cascade is inconsistent with me taking methyl Beto when I take a dental Sobe 12. Oh, completely different. Speaker 2: (55:07) Wow. So this is getting really granular for each individual. And this is what makes me so excited. And, but before we go on, we have to go and cover off the hormone report. This is something that I and, and this is, you know, for me and any woman, but I wanted to focus a little bit more in on the woman. We've got very complicated hormones, households, but this was the cascade for men and women is very, very similar, isn't it? Yes Speaker 3: (55:33) It is. It's just remarkably, this is what we taught at the cost on the weekend after introducing genomics, it was the first open to eyes that the cascade, the circadian rhythm with which the human body converts progesterones into androgens, androgens to estrogens, men, we do not have a monopoly over androgens. Women, you do not have a monopoly over estrogens. In fact, your estrogens come from androgens. Men, we have estrogens. It's just a matter of the circadian rhythm. When is it happening? How quickly is it happening? And of course, ultimately how much of any of these hormones are produced. And then the final component is how responsive are you, the the woman's body, all things equal. She's designed with the estrogen receptors to be more responsive to estrogen. She responds to androgens as well. Conversely, for men. Now keep in mind something as simple as, I can't believe how many clinicians do not realize how an androgen or estrogen receptors. Speaker 3: (56:32) Now let's stop there for this cascade. We can talk about all of the things about how hormones are produced and how they're metabolized and so on and so forth. But ultimately, how is estrogen affecting your body? Lisa, you're a young woman. You're making estrogen as if you're menstruating or if you want hormone replacement, there's likely some estrogens in your body, one way or the other when estrogen binds to your estrogen receptor. And to the degree that that can happen, mind you, because there are variations to that fidelity, this complex estrogen. So the estrogen receptor androgen to Stastrom, DHT to the androgen receptor. These complexes are some of the most potent DNA transcribing complex. They go into the nucleus and the churn on genes. This is how estrogen and testosterone impacts the human body. They live. They're not just, I don't know, causing breast development or, or, or, or Andrew demise in the book. Speaker 3: (57:39) They do that by churning on the genes that cause the cells to behave in a more underutilized manner or more estrogen. So the first thing I want, our audience needs, our clinicians, we need to re re climatize reacquaint ourselves with that. These hormones potently DNA transcribing, they go into the nucleus and they turn on and off genes. That is why they are not to be dealt with trivially. Number one. Number two, in a menstruating woman. Now I just told you when estrogen enters a cell, I did binds its receptor. It's not just staying in the, in the Maloo of the South, it's going in to the volts, the nuclear volts and churning on and turning off genes. Wow. When you look at the ministerial cycle of, of a, of a relatively normal, repeatable menstrual cycle, you will notice something radically important over the course of 28 days. Speaker 3: (58:43) The human female body isn't exposed to estrogen at the same amount every day, not at all. The human female body in 20 days only has about a six day or so window in which your estrogens that are really elevated and then it comes down. In other words, what is this telling us from a human biology perspective? It's saying that the type of gene expression changes the epigenetic phenomena that estrogens cause on your operating manual. You don't want that to be consistent and constant across the month, and this is very frightening when you look at contraceptive pill or hormone replacement therapy. So it's most certainly very frightening. That is not, let me be clear. That is not to say that there isn't a place or a time for these things. You know they are absolutely a young woman has to have the right to how she treats her body and what she does. Speaker 3: (59:47) But there is a place in time you at least be equipped, at least be empowered before you make this decision as to a knowing what it's doing for you. Say, okay, look for these few months of my life, for these couple of years of my life, this is going to be a bit more important that I take these precautions, for example, but you should know that to do so indefinitely, month after month, year after year. Now they've got clinicians encouraging young woman not to even have a bleed through. There's no point for even the bleed. So just stay on the, you know, constant level, 24 seven three 65 15 years. How is this compatible with normal human physiology? When you understood what I just said? Yep. Now let's go a step further than that. You see estrogens do what we just said. They bind their receptors, they go into the cell so they go into the nucleus. Speaker 3: (01:00:47) They change gene expression as they're meant to for brief periods during the month. Fair enough. Now, once those estrogens have done what they've done for those days, then the point of it is there's a circadian rhythm. The body breaks down those estrogens metabolizes them by a transforms them so that they're no longer active. They've been neutralized, and then we hit repeat, rinse and repeat, and we start a new cycle. But here's the point. Every a woman, Lisa, every a woman, a man for that matter, but let's focus on the ladies when she made her estrogens or she took her estrogens, because even whether you take it or whether you make it innately or you take it, it doesn't matter. You've got to metabolize the estrogen. Now, every young woman can metabolize estrogens into three byproducts. I estrogen 400 Z estrogen, 16 hours for hydroxy estrogen. Every human being does this, and this is a crucial point. Speaker 3: (01:01:49) Absolutely. But these three metabolites do not impact yourselves in the same way you say. If you thought of it, you've made the estrogen small window. Now you want to neutralize it so that the body isn't under its constant influence. So you want this metabolite, this estrogen, this hub light to have lost bind to the receptor. You want it to last. It's estrogen Ising properties. Lo and behold, four estrogen, one of those three metabolites retains the ability to bind the estrogen receptor. In fact, some studies show it might be an even more potent comm when it, when it binds and it creates this, this common, a tutorial, Leiden and receptor, it's DNA. Transcribing effects are even more potent, much like the analogy between DHT and the androgen receptor versus testosterone. DHT dihydrotestosterone, which is a metabolite of testosterone, has a higher potency binding affinity to the androgen receptor. Speaker 3: (01:03:00) Four hydroxy estrogen is to the estrogen receptor as DHT is to the androgen receptor. Wow. The ability innate tendency of a young woman when she's faced with estrogens to make either the two hydroxy which is considered protective because has lost or the four hydroxy that inmate differentiation is radically genetically determinable. Now, if something as simple as that, Lisa, when you stitch these things together, when you understand, look, estrogen should be my body needs security and rhythm. I do not want estrogen is constant. When I break down those estrogens, I want my body to have had a break from them. And you did not know whether you were four hydroxy dominant or not. If you had a tendency to make more of the four hydroxy than the two and why is four hydroxy so naughty? Three reasons. A, it binds the estrogen receptor, not giving your body a break from the estrogen ization one to four hydroxy estrogen if you are not flushing it out of the body and how do you flush out for drugs, the estrogen through methylation, the comp gene, which is catechal methyl transfers an oops. Speaker 3: (01:04:29) Can you imagine if you were innately genetic info, hydroxy dominant and have the slow comps because now you're making too much four hydroxyestrone you have a tendency to do so. You do not have the enzymatic ability to get rid of it. Now you buy your stagnate, your four hydroxy Astrid. Do you know what full hydroxy estrogen does other than binding the estrogen receptor and Quinones? Quinones? Listen, my God, you're speaking more than some of the best medical biologists that I've spoken to. So the, the decompose into Quinones and do you know what Quinones do? They get into your DNA. They stick to, they are mutagens. They stick to your DNA, causing the DNA to not be able to unravel and repair itself and by the Quinones then cause accidents. So here's what you don't want to be. You don't want to be the young woman who is genetically predisposed to overly produce four hydroxy estrogen simultaneously, have a poor comp, simultaneously, have a low GSTT one GSTP one, which was the thing, Quinones, and then have a poor mitochondrial superoxide dismutase or antioxidation to get rid of the oxidants Speaker 2: (01:05:52) And add to that. You're in your forties or your 50s and you're making more EstroZen, Speaker 3: (01:05:57) Which is a breast tissue because it's not in the liver anymore. The liver organ, at least it was designed for that type of metabolism. You're doing this in the breasts, you know, God forbid. Okay, Speaker 2: (01:06:10) This is where the cancers can come in Speaker 3: (01:06:13) This is weird and just why we have the the epidemiologic rise during that shift where the woman's body shifts from doing that grunt work in her liver, which was designed for it to doing that grunt work in such as breast tissue, cervical tissue, an ovarian tissue and so on and so forth. Which of course the human body, the female body does not express estrogen receptors, the same level for every cell type. You know, when you were, we lobby at nine years old and you could have gone outside, you know, flat chested like any other boy and you know, and then when, when men awe kits and the body changed your elbows and forms didn't change, it was suitable zone. Those are the zones that have more estrogen receptors. Speaker 2: (01:07:03) And this is so this is how we can see like when you're looking at the phenotype, if we can go look like the the the hormone cascade just for people that are listening, it's going from producer owns and pregnenolone's into testosterone's which can sometimes go into DHT and which then go into the estrogen. Is thrown in your estradiol if you're pregnant when you're older you have more strokes coming in which are, that's coming from the the other top of testosterone isn't it? One on one and then it's means a lighter than these three path rates into the two hydroxy four h

Indian shares are likely to extend losses on Wednesday, tracking heavy selloffs in global markets after the US issued a warning to Americans to prepare for the possibility of a coronavirus pandemic. At 7:22 am, the SGX Nifty was trading 94 points or 0.8 percent lower at 11,724. Bandhan Bank, which received RBI nod to expand its branch network, and Yes Bank, which was downgraded by Care Ratings, are among the key stocks in focus today.

Tonight’s segments – A pair of kick ass Aussies; the VXR8 Bathurst and the Maloo, Clarkson and Mae faffing about with an ad for the new TDI Scirocco, a sad robot review of the V12 Vantage, and star in a reasonably priced car Jay Leno. Episodes are finally on Motor Trend! – https://www.motortrendondemand.com/topgear Scooter fantastictude – https://scontent-sea1-1.xx.fbcdn.net/v/t1.0-9/71847424_10105499040560623_6270250981955469312_o.jpg?_nc_cat=107&cachebreaker=hd&_nc_oc=AQmHDs5MYZl5SuXw_qhxM2IABm1-BQjczQrcrhzJp2QZyHuevcVhpbfn9CzYrwC2bw0&_nc_ht=scontent-sea1-1.xx&oh=131183a06e15c916b039d3aa148294a8&oe=5E1F7814 American Maloo! – https://www.whichcar.com.au/news/hsv-gts-r-maloo-appears-america A week with a Maloo – https://www.automobilemag.com/news/one-week-2016-hsv-maloo-r8-lsa/ Doug chatting about the SSR – https://www.youtube.com/watch?v=0-eWzZuXUQg Ofcom (?) got cranky about the suicide ad – https://www.campaignlive.co.uk/article/jeremy-clarksons-top-gear-vw-ad-guilty-breaking-ofcom-rules/965473 All of the ads in potato quality – https://www.youtube.com/watch?v=-nD08yxGisQ Leno’s collection – https://blog.dupontregistry.com/jay-lenos-garage/jay-lenos-car-collection/ A V12 Vantage swan song – https://www.topgear.com/car-news/supercars/heres-why-well-miss-the-aston-martin-v12-vantage-supercar Facebook – https://www.facebook.com/topgearrearview/ Music – In Heaven by DeCreek, licensed under a Creative Commons Attribution License

Indian benchmark indices BSE Sensex and NSE’s Nifty50 are likely to open higher on Friday following gains in global equities and ahead of the Reserve Bank of India’s monetary policy decision. The RBI is expected to cut the key repo rate by 25 basis points, according to most economists polled by CNBC-TV18. The two indices closed lower for the third straight session on Thursday. The Sensex settled 198.54 points lower, or 0.52 percent, at 38,107. The Nifty also slipped nearly 46 points, or 0.40 percent, to end at 11,314. At 7:40 AM, the SGX Nifty futures traded 25 points, or 0.22 percent, higher at 11,384, indicating a positive start for the Sensex and the Nifty 50.

Benchmark indices BSE Sensex and NSE’s Nifty 50 are set for a mixed start on Monday following muted sentiment in the global markets and ahead of the Reserve Bank of India’s monetary policy decision later this week. Asian shares traded cautiously after news that the US administration is considering delisting Chinese companies from US stock exchanges. Oil prices edged higher, rebounding from a two-week low in the previous session, although gains were checked by concerns about the outlook for the global economy. At 7.30 AM, the SGX Nifty futures traded 10 points, or 0.09 percent, lower at 11,575, pointing to a mixed start for the Sensex and the Nifty50.  

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MF101 is an oven-fresh mutual fund podcast by Aditya Birla Sun Life Mutual Fund in association with Bloomberg|Quint. This is the fourth episode of MF101 with our very own chef Mr. Vineet Maloo, Fund Manager, Aditya Birla Sun Life Mutual Fund. Mr. Maloo has extensive experience and has worked with Aditya Birla Sun Life Mutual Fund for more than 12 years. He is a qualified Chartered Accountant.The conversation revolves around key recipes such importance of asset allocation, working of hybrid mutual funds, what is static investing versus dynamic investing, and much more. You can listen to this show and other awesome shows on the new and improved IVM Podcast App on Android: https://ivm.today/android or iOS: https://ivm.today/ios

Time Codes: 00:30 - Introduction 02:49 - Introducing Krystal, and a Farewell to Paul 07:24 - 3x4 17:44 - The Creepy Case Files of Margo Maloo: The Monster Mall 32:40 -Sheets 42:54 - Wrap up 43:42 - Contact us On this episode of the Comics Alternative's Young Readers show, Gwen is joined by her new co-host, Dr. Krystal Howard, an assistant professor in the Liberal Studies and English departments at California State University, Northridge. Krystal has been reading, writing about, and teaching children's and YA comics for a number of years and has a particular interest in gender and comics studies. In 2017, Krystal's essay “Gothic Excess and the Body in Vera Brosgol's Anya's Ghost” appeared in Gwen's co-edited volume (with Michelle Ann Abate), Graphic Novels for Children and Young Adults, and she has another comics-related essay, “Comics Grammar in Neil Gaiman and Dave McKean's Picture Book Collaborations” that is forthcoming in The Artistry of Neil Gaiman: Finding Light in the Shadows. Regular listeners to the Young Readers show will already know Krystal from her spot as a panelist last summer on a special roundtable that Gwen and Paul Lai hosted on the future of children's and YA comics. Before they begin discussing the books for this month's show, Gwen and Krystal mention the wonderful contributions of Paul Lai, who has recently graduated with his doctorate from the School of Education in Language, Literacy, and Culture at the University of California, Berkeley, and who has begun a new position as Director of UC Berkeley's prestigious BE3 program, which stands for Berkeley Educators for Equity and Excellence. Paul intends to return to the Comics Alternativefamily from time to time as a podcaster, and Gwen and Krystal wish him the very best in his new role. During the main portion of the show, Gwen and Krystal discuss three new releases: Ivan Brunetti's 3 x 4, published last month by TOON Books and geared towards early elementary readers, and two Halloween-oriented middle grade graphic novels: Drew Weing's The Creepy Case Files of Margo Maloo: The Monster Mall, which is the second in the Margo Maloo series from First Second books, and Brenna Thummler's debut, Sheets, put out by Lion Forge's Cubhouse imprint. Both Krystal and Gwen found Brunetti's 3 x 4 to be a great addition to the plethora of STEM-focused comics that have been published in the last five years, including First Second's Science Comics series and Mike Holmes and Gene Luen Yang's Secret Coders. Krystal praises Brunetti for his inclusion of a diverse and eclectic group of young people, and Gwen notes that for the detail-oriented child, every page offers up an opportunity to discover the many ways that the number 12 can be divided into sets! Next, the two PhDs consider Drew Weing's follow up to his highly successful first volume of the Margo Maloos series: The Creepy Case Files of Margo Maloo: The Monster Mall. Gwen appreciates Weing's decision to continue focusing on the costs of gentrification, while Krystal notes that the inclusion of teenage characters adds a new dimension to the series. Finally, Gwen and Krystal discuss the amazing debut by Brenna Thummler, Sheets (Lion Forge), which takes place in a lake resort town and focuses on the struggles of a young woman who has become the proprietor of her family's laundromat, all while trying to fit in at middle school. Her interactions with Wendell, the ghost of an eleven-year-old boy, end up making life a lot better for both of them. Krystal points out Thummler's attention to figural placement and atmospherics, and Gwen suggests that while some of the plot points might seem a little far-fetched, the novel holds together well and deals with class conflict in a manner that is also present in Weing's Margo Maloo series. In November, Gwen and Krystal will be back with another set of books to review, as well as 2018 best-of-list recommendations for our listener's winter holiday celebrations.  

Anurag Maloo is an Indo-Asian startup innovation Community Architect who supports entrepreneurs inspired by hope to transcend very challenging conditions to rebuild economies. Regional Manager for South & Central Asia with Techstars and Startup Weekend, he is responsible for the cultivation and sustained growth of vibrant startup ecosystems in India, SAARC nations (Pakistan, Bangladesh, Nepal, Sri Lanka, Bhutan, Afghanistan, Maldives) and Central Asian countries (Kazakhstan, Tajikistan, Kyrgyzstan, Uzbekistan, Turkmenistan). He is incredibly passionate about fostering entrepreneurship, innovation ecosystem, grassroots leadership, and building strong collaborative startup communities. In this conversation with host Dawna Jones, Anurag shares what makes him tick and how he approaches communities and people ready to do something different even when in the context of war or conflict. None of this is easy which is why Anurag attracts people who hold hope for a better future, and willing to do what it takes. In some countries living is high risk illustrated by the recent death of Startup Grind's Chapter host in Mogadishu Somalia, Mohamed Sheikh Ali, who was gunned down. As chapter host he did inspiring work to support entrepreneurs. Facing To tough situations takes courage, vision and empathy in order to work together to create better options that transcend existing conditions. Yet that is what it takes in emerging economies and for citizens in countries working to a future with greater hope. If you haven't already listened to the impACT interview please do. You will find Anurag Maloo on social media channels listed here: tps://about.me/anuragmalooHost Dawna Jones specializes in transformational insights that activate the power of the human spirit to work creatively with designing a future with hope and connection to what matters. See acast.com/privacy for privacy and opt-out information.

Anurag Maloo is an an Indo-Asian startup innovation Community Architect. In this episode he interviews the host of the Evolutionary Provocateur and the Insight to Action podcast, Dawna Jones on her personal journey, sacrifices, the meaning of friends and staying true to purpose. In early 2002-2004 Dawna shifted her role from facilitating change to facilitating leadership and broader consciousness to support ethical decision making. Things did not go according to plan but the experience has been mind expanding and a process of aligning with personal power. Anurag and Dawna chat about the personal story people don't often see behind the scenes. Dawna Jones specializes in seeing what others don't - insights that allow for a shift in perspective, clearing of blocks and barriers to human and organizational potential. She is the author of Decision Making for Dummies, contributor to The Intelligence of the Cosmos by Ervin Laszlo and co-author of From Hierarchy to High Performance. Her work engages deeper aspects of human intelligence to move collectively forward on the large complex issues that face companies and the planet through ethical decision-making and bold leadership.Find Dawna on Twitter at EPDawna_Jones, LinkedIN and FromINsightToAction.com See acast.com/privacy for privacy and opt-out information.

Join Praveen Maloo, Product Evangelist for Microsoft Teams, and Jason Ritchey, Vice President of Client Delivery at Valorem, a consulting firm focused on digital transformation, as they discuss  Valorem's  journey with Teams. We will look at real-life use cases, adoption best practices and  how collaboration  with Teams is driving business agility across the organization

I catch up with Kurt Maloo, the former lead singer of Double, who had one of the best one-hit wonder songs, not just of the 1980’s, but of all-time with “The Captain of Her Heart.” Kurt tells me his relationship with the song, its path to success and if there are any covers of the song that he likes.

In the 1980s, as one half of the brilliant pop duo Double, Kurt Maloo coauthored and sang the most enduring hit Switzerland has ever produced: “The Captain of Her Heart.”Maloo continued his career solo again and released, under his own name, Single (1990), Soul & Echo (1995), Loopy Avenue (2006), Summer of Better Times (2009) and "What About (2014)". Since 2007, he has been performing with his own band and played several concerts and festivals, including NuNote Lounge Fest in Moscow.

Gwen and Andy both are astounded that the end of the year is almost upon them, and with that in mind, they've picked their favorite books of 2016 for young readers. The Two People with PhDs each picked five books in the children's category and five books in the intermediate/young adult (YA) category, but something odd happened: their lists were almost identical! In the children's category, Gwen and Andy both chose the following four books, many of which they have already discussed on previous episodes. Nathan Hale's Hazardous Tales: Alamo All-Stars, by Nathan Hale (Harry N. Abrams) Hippopotamister, by John Patrick Green (First Second) The Creepy Case Files of Margo Maloo, by Drew Weing (First Second) Bera the One-Headed Troll, by Eric Orchard (First Second) Andy diverged by picking Bert's Way Home, by John Martz (Koyama Press), the story of an orphan named Bert who's no regular orphan, but an orphan of time and space, stranded on Earth after a cosmic accident. Gwen's final pick in this category was Blip! a TOON Level 1 book by Barnaby Richards about a robot whose vocabulary consists of only one word (“Blip”) as he tries to find his way through an unfamiliar planet. In the Intermediate/YA category, Gwen and Andy also agree on their first four titles: March: Book Three, by John Lewis, Andrew Aydin, and Nate Powell (Top Shelf), the third and final book in the March trilogy. March: Book Three is also a noteworthy book in that it recently won the prestigious National Book Award for Young People's Literature, becoming the first graphic novel to win the award. Camp Midnight, by Steven T. Seagle and Jason Adam Katzenstein (Image) Paper Girls, Vol. 1, by Brian K. Vaughan and Cliff Chiang (Image) Snow White, by Matt Phelan (Candlewick Press) The two people with PhDs also had the great pleasure of interviewing Matt Phelan on the show last month. You can listen to that interview here. Andy's final choice was Mighty Jack, by Ben Hatke, a title previously discussed on the show back in August. For Gwen's final choice, she picked Delilah Dirk and the King's Shilling, by Tony Cliff (First Second), a book previously discussed by Derek and Sean in its original webcomics format. This volume picks up where the first volume, 2013's Delilah Dirk and the Turkish Lieutenant, left off. At the end of the show, Gwen mentioned a new all ages wordless comic that she learned about on Dr. Debbie Reese's excellent American Indians in Children's Literature blog, Jonathan Nelson's The Wool of Jonesy: Part I, published by Native Realities Press. Here is the blurb from the publisher's website: Written and illustrated by Diné artist Jonathan Nelson, The Wool of Jonesy #1 tells the first story of Jonesy the Sheep and his adventures out on the rez. As Jonesy heads out to explore life after high school he finds himself discovering and dreaming. The wonderfully illustrated story gives young and old alike a simple and enchanting view of reservation life through the eyes of an amazing character! Readers can check out Debbie Reese's review. Gwen and Andy hope that these titles might be considered for gift for the holiday season. You really can't go wrong with any of these titles. We can't wait to see what great comics are in store for us in 2017. You can be sure we'll pass all the information along to you. Happy reading!

Time Codes: 00:25 - Introduction 02:50 - Context for the First Second spotlight 05:56 - Brief mention of Mighty Jack 06:56 - Varmints 11:46 - Quirk's Quest: Into the Outlands 27:52 - Bera the One-Headed Troll 39:18 - The Creepy Case Files of Margo Maloo 55:44 - Wrap up 57:03 - Contact us Gwen and Andy are back with something different for the Young Readers edition of The Comics Alternative: their very first publisher spotlight on First Second Books. The Two People with PhDs have looked at many First Second books in the past, but this time they're looking at the publisher's fall selections. (Since they covered Ben Hatke's Mighty Jack in their August show, Gwen and Andy give it just a brief mention here, but you should definitely check it out!) They begin with Andy Hirsch's Varmints, a wild adventure set in the Old West with sister and brother Opie and Ned, searching for the man who shot their ma. If you like Western stories filled with action, action, and more action, this is the book for you. (And don't miss the Comics Alternative interview with Andy Hirsch!) Next, they turn to Quirk's Quest: Into the Outlands by Robert Christie and Deborah Lang, an exploration adventure with the crew of the H.M.S. Gwaniimander under the command of Captain Quenterindy Quirk. Quirk's voyage quickly meets with a near disaster as his crew discovers a land of deadly giants, a valley of weird creatures, and a sorceress who may or may not have the crew's best interests in mind. Christie and Lang's characters may look like something out of a Jim Henson production, but the world they've created is unique and compelling. Eric Orchard's Bera the One-Headed Troll is yet a different type of quest story, this one featuring the titular troll and her owl companion Winslowe as they discover an abandoned human baby on their pumpkin patch island. Everyone seems to want the child for their own nefarious purposes, but Bera is determined to keep the baby safe from mermaids, witches, and a creature called Cloote, the former head witch of the Troll King. Orchard's wonderfully bizarre illustrations combine with masterful storytelling that's filled with humor and depth. Finally, the Two People with PhDs look at The Creepy Case Files of Margo Maloo by Drew Weing, the story of a young girl who's a “monster mediator,” someone who patrols the streets of Echo City for trolls, ogres, and ghosts. And they're all afraid of her! (Note: Sean and Derek discussed the online version of this series in the June webcomics episode.) Andy and Gwen both agree that Margo Maloo is a spectacular story, but it's so much more. It's also a book that works on multiple levels touching on the fears, prejudices, and anxieties of us all. First Second is a treasure trove of great books and Gwen and Andy hope that you'll want to read them all!

On this month's webcomics episode, Sean and Derek have some fun things in store. They begin with two currently ongoing titles, The Abominable Charles Christopher and The Creepy Casefiles of Margo Maloo. The former, written and drawn by Karl Kirschel, is a long-running series that has been around since June 2007. The guys discuss the webcomic's irregular schedule — Kirschel posts updates whenever his work for DC and Marvel, especially Gotham Academy, allows — and, more importantly, the artist's obvious love of his subject matter. Margo Maloo, a more recent webcomic, is Drew Weing's fun all-age story about a monster-filled underworld outside of adult awareness. The June episode wraps up with a trip down memory lane. Breakfast of the Gods is a completed webcomic tapping into the history of breakfast cereals. Its creator, Brendan Douglas Jones, uses the mascots of General Mills, Kellogg's, Post, Quaker Oats, Ralston, Nabisco, and other breakfast cereal producers for an epic tale pitting the vitamin-packed forces of good against the shadowy legions of morning nutrition.

Kurt Maloo is a Swiss singer-songwriter, composer, and record producer. He first achieved international success in 1986, as the singer and front man of the pop-jazz duo Double with the hit single, “The Captain of Her Heart“.

Kurt Maloo wrote and sang one of the most iconic and unique hit songs of all time with "The Captain of Her Heart" which reached #16 in 1986 in the US. That's one of those songs almost everyone knows, but maybe not everyone knows who sings it. Kurt, along with creative partner Felix Haug, put out two albums as Double before disbanding in the late 80s. Unfortunately, Felix passed away in 2004 ending any potential for a Double reunion. But, "Captain" is still a standard and continues to be played all over the world for subsequent generations, which has provided a very nice life for Kurt and has freed him up to continue to forge a solo career on his own terms. Get to know the man behind the song!

Agradece a este podcast tantas horas de entretenimiento y disfruta de episodios exclusivos como éste. ¡Apóyale en iVoox! El que fuera cantante de la banda suiza Double, que triunfó en los 80 con "The Captain of her Heart", tiene un nuevo disco en solitario que te presentamos en esta edición. También los recientes trabajos de Mr President, Eric Darius, U-Nam, Darren Barrett y Patrick Bradley. En el recuerdo recuperamos música del baterista Idris Muhammad y de la vocalista Rebecca Dorsey.Escucha este episodio completo y accede a todo el contenido exclusivo de Cloud Jazz Smooth Jazz. Descubre antes que nadie los nuevos episodios, y participa en la comunidad exclusiva de oyentes en https://go.ivoox.com/sq/27170

Me and Rolly Maloo by Janet S. Wong An unpopular girl cheats on a math test when the most popular girl in school asks her to give her answers.   Audience: Kids and Teens