POPULARITY
2 episodes with Ugi
2 episodes with Ugi
30 episodes with Ugi
4 episodes with Ugi
2 episodes with Ugi
Surgical conferences are a forum of the profession–where we all gather to socialize, share clinical experiences, promote academic work, and learn from each other. But what goes into putting these conferences together? In this next installment of the BTK/ASGBI collaborative series, Jon Williams and ASGBI co-hosts Kellie Bateman and Jared Wohlgemut welcome Mr. Dimitrios Damaskos from Edinburgh and Dr. Anne Lidor from the University of Wisconsin to take a look behind the scenes of conference planning. We'll cover logistics, program selection, how surgical societies strive to support their members and trainees, and much more! Mr Dimitrios Damaskos, initially from Greece, he came to the UK for his fellowship and is a UGI and Emergency General Surgical Consultant with an interest in abdominal wall surgery based in The Royal Infirmary Edinburgh. He is the current Director of Scientific Programme for ASGBI and responsible for organising our main International Congress which this year happens to be in Edinburgh. He has also held numerous other events for surgical societies including the British Hernia Society. Dr. Lidor serves as the program chair for the Society for American Gastrointestinal and Endoscopic Surgeons (i.e. SAGES), which is a wide-reaching US-based international surgical society that encompasses many facets of general surgery. The SAGES Annual Meeting was just last month, and is a great opportunity for surgeons to convene and share clinical experiences, academic work, and professionally connect. Dr. Lidor completed medical school at the New York Medical College, and then moved on to George Washington University for general surgery residency training. Following residency, she moved to Baltimore to Johns Hopkins where she completed her MIS/Bariatric Surgery fellowship and subsequently stayed on as a faculty surgeon. After years at Hopkins during which she held many education leadership roles both at the medical school and as fellowship director, she moved to the University of Wisconsin to become Chief of Minimally Invasive and Bariatric Surgery, a role she continues to hold today. If you enjoyed this episode, stay tuned for more upcoming BTK/ASGBI collaborative content. If you have any questions or comments, please feel free to reach out to us at hello@behindtheknife.org. Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen
The 2024 Cigar Coop Cigar of the Year is the Perdomo 30th Anniversary Maduro Epicure. Perdomo Cigars is not known for frequently releasing all-new lines. As a result, there is a heightened level of excitement when a new Perdomo release occurs. There was understandably a lot of buzz when the company did have a big new release in 2023. Additionally, it was a special one as it commemorated a significant milestone: 30 years in business for Nick Perdomo and his family. Full Details: https://wp.me/p6h1n1-uGI
The 2024 Cigar Coop Cigar of the Year is the Perdomo 30th Anniversary Maduro Epicure. Perdomo Cigars is not known for frequently releasing all-new lines. As a result, there is a heightened level of excitement when a new Perdomo release occurs. There was understandably a lot of buzz when the company did have a big new release in 2023. Additionally, it was a special one as it commemorated a significant milestone: 30 years in business for Nick Perdomo and his family. Full Details: https://wp.me/p6h1n1-uGI
UGI Corp. (UGI) ripped to highs it hasn't seen in over a year after sharing an EPS beat in its 4Q earnings report despite a sales miss. George Tsilis says there's more to UGI's breakout behind the bullish attention. ======== Schwab Network ======== Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribe Download the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185 Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7 Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watch Watch on Vizio - https://www.vizio.com/en/watchfreeplus-explore Watch on DistroTV - https://www.distro.tv/live/schwab-network/ Follow us on X – https://twitter.com/schwabnetwork Follow us on Facebook – https://www.facebook.com/schwabnetwork Follow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about
On this Live Greatly podcast episode, Kristel Bauer sits down with Willie Pietersen, author of Leadership—The Inside Story: Time-Tested Prescriptions for Those Who Seek To Lead. Willie shares stories, experiences and the secret sauce of leadership learned from his time being CEO of multibillion-dollar businesses, a professor at Columbia University's Graduate School of Business, and a consultant to some of the world's biggest and best-known organizations. Tune in now! Key Takeaways From This Episode How leadership is all about people Some big lessons Willie learned amid his leadership journey How to get better at receving feedback and why it is important Stories about what makes a great leader About Willie Pietersen: Willie Pietersen was raised in South Africa, and received a Rhodes Scholarship to Oxford University. After practicing law, he embarked on an international business career. Over a period of twenty years he served as the CEO of multibillion-dollar businesses such as Lever Foods, Seagram USA, Tropicana and Sterling Winthrop's Consumer Health Group. In 1998, Willie was named Professor of the Practice of Management at the Columbia University Graduate School of Business. He specializes in strategy and the leadership of change, and his methods and ideas, especially Strategic Learning, are widely applied within Columbia's executive education programs, and also in numerous corporations. He has served as a teacher and advisor to many global companies, including Aviva, Bausch & Lomb, Boeing, Chubb Corp., Deloitte, DePuy, Electrolux, Ericsson, ExxonMobil, Henry Schein, Inc., Federal Home Loan Bank of Atlanta, Novartis, Salt River Project, SAP, UGI, United Nations Federal Credit Union and also the Girl Scouts of the USA. Willie is the author of three books and numerous articles. His latest book is Leadership—The Inside Story: Time-Tested Prescriptions for Those Who Seek to Lead. Connect with Willie: Website: https://williepietersen.com/ LinkedIn: https://www.linkedin.com/in/willie-pietersen-286b149/ Get Willie's Book: https://williepietersen.com/books/leadership-the-inside-story-time-tested-prescriptions-for-those-who-seek-to-lead/ About the Host of the Live Greatly podcast, Kristel Bauer: Kristel Bauer is a corporate wellness expert, popular keynote and TEDx speaker, and the host of top-rated self-improvement podcast “Live Greatly”. Kristel is an Integrative Medicine Fellow & Physician Assistant with clinical experience in Integrative Psychiatry, giving her a unique perspective into optimizing mental well-being and attaining a mindset for more happiness and success in the workplace and beyond. Kristel decided to leave clinical practice in 2019 when she founded her wellness platform “Live Greatly” to share her message around well-being and success on a larger scale. With a mission to support companies and individuals on their journeys for more happiness, success, and well-being, Kristel taps into her unique background in healthcare, business, and media, to provide invaluable insights into high power habits, leadership development, mental well-being, peak performance, resilience, sales, success, wellness at work, and a modern approach to work/life balance. Kristel is the author of Work-Life Tango: Finding Happiness, Harmony and Peak Performance Wherever You Work (John Murray Business November 19, 2024). Kristel is a contributing writer for Entrepreneur and she is an influencer in the business and wellness space having been recognized as a Top 10 Social Media Influencer of 2021 in Forbes. A popular speaker on a variety of topics, Kristel has presented to groups at APMP, Bank of America, Commercial Metals Company, General Mills, Northwestern University, Mazda, Santander Bank and many more. She has been featured in Forbes, Forest & Bluff Magazine, Authority Magazine & Podcast Magazine, has contributed to CEOWORLD Magazine & Real Leaders Magazine, and has appeared on ABC 7 Chicago, WGN Daytime Chicago, Fox 4's WDAF-TV's Great Day KC and Ticker News. Kristel lives in the Chicago area with her husband and their 2 children. She can be booked for speaking engagements worldwide. To Book Kristel as a speaker for your next event, click here. Website: www.livegreatly.co Follow Kristel Bauer on: Instagram: @livegreatly_co LinkedIn: Kristel Bauer Twitter: @livegreatly_co Facebook: @livegreatly.co Youtube: Live Greatly, Kristel Bauer To Watch Kristel Bauer's TEDx talk of Redefining Work/Life Balance in a COVID-19 World click here. Click HERE to check out Kristel's corporate wellness and leadership blog Click HERE to check out Kristel's Travel and Wellness Blog Disclaimer: The contents of this podcast are intended for informational and educational purposes only. Always seek the guidance of your physician for any recommendations specific to you or for any questions regarding your specific health, your sleep patterns changes to diet and exercise, or any medical conditions. Always consult your physician before starting any supplements or new lifestyle programs. All information, views and statements shared on the Live Greatly podcast are purely the opinions of the authors, and are not medical advice or treatment recommendations. They have not been evaluated by the food and drug administration. Opinions of guests are their own and Kristel Bauer & this podcast does not endorse or accept responsibility for statements made by guests. Neither Kristel Bauer nor this podcast takes responsibility for possible health consequences of a person or persons following the information in this educational content. Always consult your physician for recommendations specific to you.
The federal government gave Pennsylvania a whole lot of money for its largest solar project yet. SEPTA wants riders to quit smoking pot while using the transit system. UGI will be doing some pipe replacement starting today. Plus, watch out this April Fool's, because this city's the number one for pranksters.
When is the last time someone said to you, “woah you've really changed.” If it's been a while, then you might need to take a minute to measure your your UGI.
The UK government has announced plans for a global AI Safety Summit, to be held in Bletchley Park in Buckinghamshire, outside London, on 1st and 2nd of November. That raises the importance of thinking more seriously about potential scenarios for the future of AI. In this episode, co-hosts Calum and David review Calum's concept of the Economic Singularity - a topic that deserves to be addressed at the Bletchley Park Summit.Selected follow-ups:https://www.gov.uk/government/news/uk-government-sets-out-ai-safety-summit-ambitionshttps://calumchace.com/the-economic-singularity/https://transpolitica.org/projects/surveys/anticipating-ai-30/Topics addressed in this episode include:*) The five themes announced for the AI Safety Summit*) Three different phases in the future of AI, and the need for greater clarity about which risks and opportunities apply in each phase*) Two misconceptions about the future of joblessness*) Learning from how technology pushed horses out of employment*) What the word 'singularity' means in the term "Economic Singularity"*) Sources of meaning, beyond jobs and careers*) Contrasting UBI and UGI (Universal Basic Income and Universal Generous Income)*) Two different approaches to making UGI affordable*) Three forces that are driving prices downward*) Envisioning a possible dual economy*) Anticipating "the great churn" - the accelerated rate of change of jobs*) The biggest risk arising from technological unemployment*) Flaws in the concept of GDP (Gross Domestic Product)*) A contest between different narratives*) Signs of good reactions by politicians*) Recalling Christmas 1914*) Suspension of "normal politics"*) Have invitations been lost in the post?*) 16 questions about what AI might be like in 2030Music: Spike Protein, by Koi Discovery, available under CC0 1.0 Public Domain Declaration
Welcome to this episode, where we explore the details of risk management and its pivotal role in financial decisions. Starting off, we examine NVIDIA's recent earnings report and its far-reaching implications for the semiconductor industry. Our news of the week extends to CVS's strategic entry into the biosimilar arena, exploring how it could reshape its role in the healthcare sector. Our main topic revolves around the critical subject of risk and its management in the quest for financial independence. We navigate through the strategies of risk mitigation, examining portfolio diversification, asset allocation, and the balance between stability and returns. Complex concepts such as risk appetite and tolerance find their place in our discussion. Wrapping up, we answer questions from our community, providing insights into investment prospects and market dynamics. Key tickers include NVDA, CVS, MO, MPW, AD.AS, UGI, ADYEN, NEE, TROW, BATS, and DIS
Straight from Benzinga newsdesk, hosts Michael O'Connor and David Willey bring you the market news and stocks to watch.Subscribe to our Stocks To Watch Newsletter here : https://go.benzinga.com/sales-page-187126583617110118712659AY,UGI,GS,TSLA,NFLXContinued from yesterdays dividend talk:Atlantica Sustainable Infrastructure plc (NYSE:AY)Dividend Yield: 7.50%RBC Capital analyst Shelby Tucker reiterated an Outperform rating with a price target of $34 on May 8, 2023. This analyst has an accuracy rate of 71%.JP Morgan analyst Mark Strouse maintained a Neutral rating and cut the price target from $30 to $28 on March 2, 2023. This analyst has an accuracy rate of 79%.Recent News: Atlantica Sustainable posted a narrower-than-expected first-quarter loss.UGI Corporation (NYSE:UGI)Dividend Yield: 5.79%Barclays analyst Theresa Chen maintained an Underweight rating and slashed the price target from $40 to $37 on April 18, 2023. This analyst has an accuracy rate of 71%.Wells Fargo analyst Sarah Akers maintained an Equal-Weight rating and increased the price target from $41 to $42 on Jan. 10, 2023. This analyst has an accuracy rate of 69%.Recent News: UGI is expected to announce the results of its third fiscal quarter earnings on Aug. 2, 2023.todays earnings outlooks:Wall Street expects The Goldman Sachs Group, Inc. (NYSE:GS) to post quarterly earnings at $3.18 per share on revenue of $10.84 billion before the opening bell. Goldman Sachs shares gained 0.2% to $337.80 in after-hours trading.Analysts are expecting Tesla, Inc. (NASDAQ:TSLA) to have earned 81 cents per share on revenue of $24.53 billion for the latest quarter. The company will release earnings after the markets close. Tesla shares fell 0.2% to $292.69 in after-hours trading.Analysts expect Netflix, Inc. (NASDAQ:NFLX) to report quarterly earnings at $2.84 per share on revenue of $8.28 billion after the closing bell. Netflix shares rose 1.2% to $480.70 in after-hours trading.Hosts:Michael O'Connor , Benzinga NewsdeskReach out to Michael at michaeloconnor@benzinga.comBenzinga Strategy DevelopmentDavid Willey , Benzinga NewsdeskReach out to David at davidwilley@benzinga.comPartnership Contentpro.benzinga.comIf you have ideas for stocks we should cover or have feedback about the info or presentation, please drop us a line at newsdesk@benzinga.com or aslicoskun@benzinga.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
In this podcast, Alan Barkun, MD, speaks about the management of patients with upper gastrointestinal (UGI) bleeding, including risk stratification, pre-endoscopic assessment of patients, endoscopy, and the management of patients following endoscopy. Dr Barkun also spoke about these topics during his session at The American College of Gastroenterology Annual Scientific Meeting 2022 titled “State of the Art Lecture: Risk Stratification and Treatment of UGI Bleeding.”
UGI customers can expect their bills to go up even more thanks to a recent rate hike approval. Meanwhile, principals of schools in Indiana County are looking to shut down rumors concerning kitty litters. One Bed Bath & Beyond in Pennsylvania will be one of many nationwide that will shut its doors. Finally, one museum says 2022 is a year that you can really sink your teeth into.
“Ho trovato la parte migliore di me”: è questo il titolo della canzone registrata da 7 ragazzi con disabilità intellettiva, protagonisti di un laboratorio di rap terapia condotto da Zuli, musicista molto noto nell'underground torinese e non solo. Il progetto “Me too” L'iniziativa (finanziata dal bando della Regione Piemonte “Progetti speciali per persone con disabilità”, ndr) fa parte di un progetto più ampio di inclusione lavorativa, nominato “Me too”, promosso dalla Cooperativa Sociale Patchanka in collaborazione con la Città di Torino, l'Unione Montana dei Comuni delle Valli Chisone e Germanasca, Coldiretti Piemonte, Diaconia Valdese, Cooperativa Paradigma, UGI e Fondazione Paideia
The ABM Conversations Podcast - for B2B marketing professionals
In this episode, Ugi Djuric, the CEO and founder at Contenthorse, joins us to discuss ROI-led content, i.e., how you get a decent return on investment from your content. Ugi has worked on some of the most exciting SaaS projects and has delivered exceptional results. For instance, he and his team have helped Lemlist go from $50k to $3m ARR in 1 year. In this episode, he talks about: 1. What is ROI-led content marketing? Why should you focus on it? 2. What type of content should a company create for the best performance at specific stages? And how can they derive it strategically? 3. What are some common mistakes you see founders making with content, and what's the alternative? 4. What is a $500k ARR article, and what is its anatomy? 5. How to achieve content market fit? 6. What are some sensible non-vanity metrics that one should measure to ensure their content marketing efforts are on the right path, and a lot more...
In this episode, I interview Ugis Balmaks, the Founder of Recruiter Mill based in Budapest, Hungary, a recruitment firm specializing in helping online businesses hire the best talent to grow and scale their companies. Through the recruitment process, Ugi helps 7 and 8-figure businesses hire A-players in 6 weeks or less. After running and selling a 7-figure iPhone photography business, he discovered and learned the challenges of hiring people. He then launched a recruitment firm in 2020, has developed the skill to find the best candidate, and learned what distinguishes an A-player. He's now working to make this business a mid-six-figure and he's looking forward to adding more people to his side. Ugis has been helping so many companies in finding talented individuals to grow and scale. He also makes them understand the importance of looking for people who are the best in the role. For he says, “Always prioritize getting the best possible talent and person for the role.” This Cast Covers: A recruitment firm specialized in helping online businesses hire the best talent to grow and scale their companies. Saving the time, effort, and frustration of having to manage the hiring process while running the business at the same time. The objective is to help small businesses find A-players for their team. Breaking down the fundamentals on what to look for in a candidate, how to research them, ways to drive applications, and details on the filtering process. An experienced and creative recruiter in the online marketing space. Managed to scale the previous business to high 7-figures in revenue and now working to make the current business to a mid-six-figure business. Introducing the recruitment company's proven 7-step recruitment process. How online businesses can build a team of A-players by applying the method or formula of the recruitment process. Not having the same standards as other recruitment agencies yet manifesting way more advanced standards and a well-formulated process. Additional Resources: Recruiter Mill Who By Geoff Smart Alex Hormozi __________________________ Quotes: “Make sure you can deliver a good product or system and every single step in that process needs to be streamlined.” —Ugis Balmaks “If you don't find good people, you're just going to create more problems.” —Ugis Balmaks “If you don't have reliable sales, then you should probably think about that.” —Ugis Balmaks “Always prioritize getting the best possible talent and person for the role.” —Ugis Balmaks “At the end of the day, you have your own responsibility, nothing happens if you don't do anything.” —Ugis Balmaks __________________________ Music from https://filmmusic.io “Cold Funk” by Kevin MacLeod https://incompetech.com. License: CC by http://creativecommons.org/licenses/by/4.0
Discover how you can become a thought leader and share your niche through podcasting Learn what you should avoid in emails when trying to pitch yourself in a podcast Find out how you can repurpose and distribute your content online without constantly making new ones Resources/Links: Wanting to Find Out How Podcasts Can Be Your Secret Weapon in Building and Growing Your Business? Learn how you can grow your audience, share your niche and build an audience through podcasting: podino.io Summary Have you been wanting to get off from doing traditional sales and hop into podcasting– the new way of marketing? Do you want to learn how and why podcasting is your best bet in building an audience, gaining their trust, and getting more sales? Are you ready to become the best thought leader and speak your niche through podcasting? Ugi Djuric is the CEO of Contenthorse, an ROI-based content marketing agency, and the CEO of Podino, a thought leadership agency for business experts. In this episode, Ugi talks about how you can position yourself as a thought leader and speak your niche through podcasts. He also shares how podcasting can guarantee you better sales, build trust with your audience, and speak your niche with less stress. Check out these episode highlights: 01:13 – Ugi's ideal client: “Podino's ideal clients are the business experts. So, the consultants, CEOs, coaches, and the people who I'd say, need some influence in their niche, and who are selling the courses.” 01:45 – Problem Ugi helps solve: “So the main problem is that in traditional sales, in order to work, besides like, you need to be working on them more on problems to make them better. But you need to repeat them all the time.” 02:36 – Typical symptoms that clients do before reaching out to Ugi: “So first of all, measuring the strict ROI from, let's say, podcasts in the top leadership are hard, but that's a long-term game. So that's the game that we're playing in the next six months, one year, two years, three years.” 03:54 – Common mistakes that people make before they find Ugi's solution: “First of all, regarding podcasting, or taking on podcasts. Let's start with the beginning. They're writing and speaking about literally everything that's in there, let's say niche or area of expertise. The best authors do need to have their enemies.” 05:37 – Ugi's Valuable Free Action (VFA): “So the first thing is, if you process everything, you systematize everything. Right? Positioning yourself as a thought leader is not actually that hard. As I mentioned, the first thing is you need to have a strong take on opinions.” 06:31 – Ugi's Valuable Free Resource (VFR): Check out Ugi's Website: podino.io Tweetable Takeaways from this Episode: “If you process everything; you systematize everything right, positioning yourself as a thought leader is not actually that hard.” -Ugi DjuricClick To TweetTranscript (Note, this was transcribed using a transcription software and may not reflect the exact words used in the podcast) Tom Poland 00:10 Greetings, everyone, and a very warm welcome to another edition of Marketing the Invisible. My name is Tom Poland beaming out to you from Little Castaways Beach in Queensland, Australia, joined today by Ugi Djuric. Ugi, a very warm welcome, sir, from Downunder. Where are you hanging out? Ugi Djuric 00:26 In Belgrade, Serbia, my family home right now. Just woke up because the baby slept during the night. Tom Poland 00:32 For the first time in six months, so a little bit- Ugi Djuric 00:35 For the first in five or six months, yeah. Tom Poland 00:37 Well, congratulations on that! For those of you who don't know Ugi, he's the CEO of Contenthorse, which is a return-on-investment, really important words, return-on-investment-based content marketing agency, and he's the CEO of, what is fast becoming a phenomenon, Podino. It's a thought leadership agency for business experts. And our title today, Ugi, is, “How to Attract More Clients by Becoming a Thought Leader and Sharing Those Thoughts on Podcasts”. So, our seven minutes starts now, sir. Question number one is who is your ideal client? Ugi Djuric 01:13 Yeah, so Podino's ideal clients are the business experts. So, the consultants, CEOs, coaches, and the people who I'd say, need some influence in their niche, and who are selling the courses, who are selling the consultant services, whatsoever, to their business-oriented audience, marketers to build better sales, etc. Tom Poland 01:39 Business-to-business. Perfect! Thank you for that. Six and a half minutes left, sir. What's the problem you solve for them? Ugi Djuric 01:45 So, the main problem is that in traditional sales, in order to work, besides like, you need to be working on them more on problem off to make them better. But you need to repeat them all the time. So, they're not quite capable of keeping that in mind. Plus, on the other side, for selling high ticket services, high ticket businesses, like the products, your potential customers need to have trust in you. And that's what we saw. We help people become top leaders and make their audience trust them. Tom Poland 02:21 Perfect! Thank you, sir. Five and a half minutes left. Question number three, what would you say the typical symptoms are of someone who needs your services? How does someone listening to this know, “I got to find out more about Podino and what Ugi does”? Ugi Djuric 02:36 Definitely. So first of all, measuring the strict ROI from, let's say, podcasts in the top leadership are hard, but that's a long-term game. So that's the game that's we're playing in the next six months, one year, two years, three years. And the most, let's say general symptoms are, the first thing is you wish you start earlier. Right? You wish you start working on your thought leadership brand earlier because it's never too late. And the best time to do it was yesterday or 10 years ago. The second-best time is today. Right? Because it takes time. And as I said, like non-scalable sales processes. And plus, by having a personal brand in place, you will never have to worry about sales ever again. Literally, ever again! Tom Poland 03:24 That's a big problem solved. So, we're talking about your thought leaders, executive leaders, business coaches, consultants, and so on, who want to get their brand established for a particular niche specialty service. They're going to be trying stuff. So, question four, and we've got four minutes left. What are some of the common mistakes that you see people making out there in the marketplace, trying to establish themselves as a thought leader, still feeling like they're the world's best-kept secret, but they're doing stuff? What are those mistakes? Ugi Djuric 03:54 First of all, regarding podcasting, or taking on podcasts. Let's start with the beginning. They're writing and speaking about literally everything that's in there, let's say niche or area of expertise. The best authors do need to have their enemies. So, for example, my personal enemy for counter calls, let's say is content that's written for SEO, not for the users, right? So, they need to have their enemies. They need to have some strong stakes and opinions that make them different from the pool of all other people in that market. Right? So that's the first thing that they start with the wrong step. The second thing is regarding podcasting, like if they want to speak on a podcast, the first thing people do is, of course, do the calling and outreach. They're pitching to podcast hosts. And as you know, yourself, 99% of those emails are personalized. They feel spammy. They don't show that the guests care about your show. Right? So, that's the first thing. And the pool of podcasts is so small in the world. I mean, there are 2.5 million podcasts in the world but the high-quality ones really want to be heard. There are not a lot of them. And Podino's one of these opportunities. So, the two, let's say the best, biggest mistake. Tom Poland 05:09 So, getting really clear on what you stand for, but also your enemies, what you rail against, what annoys you, etc. Crafting that little message, getting invited as a podcast guest is positioning you for someone else's platform that's broadcasting a message. Let's go to question five, with just over two minutes left, one valuable free action. What would you say would be a top tip you could offer as a piece of advice that's going to help people get established as thought leaders and get their message out on other people's podcasts? Ugi Djuric 05:37 That's it. So, the first thing is, if you process everything, you systematize everything. Right? Positioning yourself as a thought leader is not actually that hard. As I mentioned, the first thing is you need to have a strong take on opinions. And you need to be sharing your secret knowledge and the knowledge that only you know, and you're niche to bring to the world, right? However, if you have the right process, it's not that hard. For example, you jump on the show, on some relevant show in your market, the podcast gets published. And you take that episode, you repurpose it into one thought leadership article for your blog. You repurpose it into 5, 10 tweets or chats for your Twitter profile, 5 to 10 YouTube videos, videos for YouTube, bring with thoughts, etc. And from one piece of content, you have like 50 plus pieces of content available with you not needing to create new content all the time. So about repurposing and distribution. Tom Poland 06:31 Super! Thank you. And so, just under a minute left, two questions to go. One valuable free resource. And I'm going to tell everyone what this is just for the sake of time. Folks, it's https://podino.io/, P-O-D-I-N-O, .io. What are they going to find there? And how will they benefit from that real quick? Ugi Djuric 06:51 So, we don't have some like lead magnet, but whoever wants to get into the “speaking on podcast game”, can go to podino.io, as you mentioned. Scroll down to the bottom of the landing page, fill down the contact form and tell us that they came to MTI, podcast with Tom Poland, and my team will personally find 15 to 30 high-quality best shows for the audience. They're the dream customer's handout. Tom Poland 07:16 Perfect! Ugi, thank you for your time. Tom Poland 07:19 Thanks for checking out our Marketing The Invisible podcast. If you like what we're doing here please head over to iTunes to subscribe, rate us, and leave us a review. It's very much appreciated. And if you want to generate five fresh leads in just five hours then check out www.fivehourchallenge.com.
Discover how you can become a thought leader and share your niche through podcasting Learn what you should avoid in emails when trying to pitch yourself in a podcast Find out how you can repurpose and distribute your content online without constantly making new ones Resources/Links: Wanting to Find Out How Podcasts Can Be Your Secret Weapon in Building and Growing Your Business? Learn how you can grow your audience, share your niche and build an audience through podcasting: podino.io Summary Have you been wanting to get off from doing traditional sales and hop into podcasting– the new way of marketing? Do you want to learn how and why podcasting is your best bet in building an audience, gaining their trust, and getting more sales? Are you ready to become the best thought leader and speak your niche through podcasting? Ugi Djuric is the CEO of Contenthorse, an ROI-based content marketing agency, and the CEO of Podino, a thought leadership agency for business experts. In this episode, Ugi talks about how you can position yourself as a thought leader and speak your niche through podcasts. He also shares how podcasting can guarantee you better sales, build trust with your audience, and speak your niche with less stress. Check out these episode highlights: 01:13 - Ugi's ideal client: “Podino's ideal clients are the business experts. So, the consultants, CEOs, coaches, and the people who I'd say, need some influence in their niche, and who are selling the courses.” 01:45 - Problem Ugi helps solve: “So the main problem is that in traditional sales, in order to work, besides like, you need to be working on them more on problems to make them better. But you need to repeat them all the time.” 02:36 - Typical symptoms that clients do before reaching out to Ugi: “So first of all, measuring the strict ROI from, let's say, podcasts in the top leadership are hard, but that's a long-term game. So that's the game that we're playing in the next six months, one year, two years, three years.” 03:54 - Common mistakes that people make before they find Ugi's solution: “First of all, regarding podcasting, or taking on podcasts. Let's start with the beginning. They're writing and speaking about literally everything that's in there, let's say niche or area of expertise. The best authors do need to have their enemies.” 05:37 - Ugi's Valuable Free Action (VFA): “So the first thing is, if you process everything, you systematize everything. Right? Positioning yourself as a thought leader is not actually that hard. As I mentioned, the first thing is you need to have a strong take on opinions.” 06:31 - Ugi's Valuable Free Resource (VFR): Check out Ugi's Website: podino.io Tweetable Takeaways from this Episode: “If you process everything; you systematize everything right, positioning yourself as a thought leader is not actually that hard.” -Ugi DjuricClick To Tweet Transcript (Note, this was transcribed using a transcription software and may not reflect the exact words used in the podcast) Tom Poland 00:10 Greetings, everyone, and a very warm welcome to another edition of Marketing the Invisible. My name is Tom Poland beaming out to you from Little Castaways Beach in Queensland, Australia, joined today by Ugi Djuric. Ugi, a very warm welcome, sir, from Downunder. Where are you hanging out? Ugi Djuric 00:26 In Belgrade, Serbia, my family home right now. Just woke up because the baby slept during the night. Tom Poland 00:32 For the first time in six months, so a little bit- Ugi Djuric 00:35 For the first in five or six months, yeah. Tom Poland 00:37 Well, congratulations on that! For those of you who don't know Ugi, he's the CEO of Contenthorse, which is a return-on-investment, really important words, return-on-investment-based content marketing a...
Ugi Djuric was Nemanja's guest of this week's Funky Marketing Show and they talked about lots of topics, but kept the focus around the way B2B SaaS companies can scale using different content marketing strategies. Ugi Djuric is Founder and CEO @ Contenthorse - the leading content marketing agency for B2B SaaS brands, and a Founder and CEO @ Podino. He's helping B2B SaaS companies reach $5m ARR with dedicated content marketing strategies, and has done it with companies such as Lemlist, GetResponse, Surfer, Poptin, Document360, Userpilot, and many others. We talked about topics such as: Why are company culture and the impact you make on your employees more important than your MRR? How can you establish company culture? How to position business owners as thought leaders in their market by creating a lot of content, jumping on podcast shows, and repurposing that content into smaller pieces? Why is user-first content more important than SEO-first content? How to establish trust that will enable you to sell your service? How to identify a bad content marketing/SEO agency? Why many articles are bad and not converting? Why AI will never replace content writers and copywriters? Take a listen, subscribe to the Funky Marketing Show, and get in touch with Ugi. Here's how you can do it. https://www.linkedin.com/in/ugljesadj/ https://twitter.com/ugidjuric https://www.contenthorse.com/ https://podino.io/ And you're welcome to follow Funky Marketing and Nemanja using the links below: https://www.linkedin.com/in/zivkovicnemanja/ https://www.linkedin.com/company/funkymarketing/ https://funkymarketing.net/ --- Send in a voice message: https://podcasters.spotify.com/pod/show/funky-marketing/message
This week, we give John the episode off, so Kate, Mark and Henry will discuss rapid stool tests in children with community acquired diarrhea, a guideline for managing patients with acute UGI bleeding, and the best duration of antibiotics for ambulatory kids with community-acquired pneumonia
Ugi is the Founder Contenthorse, an all-inclusive content marketing agency for B2B SaaS companies, and co-founder of Podino, an agency that helps business experts to grow their brand by speaking on the best podcasts in their niche. He loves building and growing things, walking around with his 2 Dalmatian dogs, and drinking beer. Connect with Ugi: https://podino.io/ https://www.contenthorse.com/ https://www.linkedin.com/in/ugljesadj/ https://twitter.com/ugljesa_djuric?lang=en +++++ Subscribe to the Podcast! ▶︎ PODCAST | https://bit.ly/3bU6D3l Please Follow & Connect with me! Link's Below ▶︎ WEBSITE | https://tyzerevans.com ▶︎ YOUTUBE | https://youtube.com/c/tyzerevans ▶︎ INSTAGRAM | https://instagram.com/tyzerevans ▶︎ FACEBOOK | https://facebook.com/grindsellelevate ▶︎ LINKEDIN | https://linkedin.com/in/tyzerevans ▶︎ TWITTER | https://twitter.com/tyzerevans ▶︎ TIKTOK | https://tiktok.com/tyzerevans ▶︎ PATREON | https://patreon.com/tyzerevans
In this episode Jennifer Hood, the HR Transformation PMO Director at UGI talks about her career in utilities, one that started over 20 years ago. She shares how she worked her way up from a Temporary Administrative Assistant to the position she holds today. Jenn is completely honest when re-telling her story, sharing all the challenges and setbacks she faced along the way. Her story is one of perserverence, determination and resilience, one that truly demonstrates her passion for learning and leading.
THIS IS INDONESIA SPESIAL HARI MUSIK NASIONAL BERSAMA PROJECT POP Dalam rangka menyambut Hari Musik Nasional, Motion Radio ngajak ngobrol beberapa musisi Indonesia, seperti PROJECT POP di "This Is Indonesia spesial Hari Musik Nasional" bareng Adit & Ugi.
Support the Show. Get the NEW AudioBook! AudioBook: Audible| Kobo| Authors Direct | Google Play | Apple SummaryHey everyone. I wanted to quickly let you know about the release of the audio version of my book, The Entrepreneur Ethos, narrated by David A. Conatser. If you want to support the show, you can buy it wherever audiobooks are sold. Links are also in the show notes. Now on to my guest today, Ugi Djuric, founder of Contenthorse. Ugi may be only 21, but he's already experienced failure as well as success in building a business. After trying to help market bars and restaurants in Belgrade, he found his niche in writing content for SaaS companies and then launched his own content marketing agency, Contenthorse. His newest venture is Podino, which seeks to incorporate podcasting into their clients' content marketing strategy; not surprisingly, soon Ugi will be launching his own podcast. Ugi shared some of the strategies they use at Contenthorse to produce good content that entices possible buyers to a site, stressing that it needs to be of high value and highly actionable. His team aims to set their content apart by doing their due diligence in researching what's out there, crowdsourcing experts, and remembering that in the end, it's people you're trying to reach — not Google. He sees the promise of artificial intelligence in helping to do research, but believes that it's only people that can make good copy. Now let's get better together. Actions to Try or Advice to Take Look for the gold when preparing content. Djuric's company has a process for researching and connecting with potential customers and experts to find the “nuggets” that others miss. Good, effective content can bring potential customers to your site, but it can't necessarily convert them into paying customers. Make sure your content strategy includes a strategy for conversion as well as attraction. Is there something your clients want or need? Consider if it's something you can provide. When Djuric's clients started asking for help with podcasts, he realized there was a need he could fill. Links to Explore Further Ugi Djuric on LinkedIn Contenthorse Ugi on Matchmaker.fm Podino Keep In TouchBook or Blog or Twitter or LinkedIn or JSYPR or Story Funnel Learn more about your ad choices. Visit podcastchoices.com/adchoices
UGI cucina... Per te! La serata dedicata al Delivery di UGI Onlus con l'intrattenimento di Radio UGI! Con la conduzione di Fabio Camusso, Luigi Brero e Stefano Nardella Ospiti: Bobo Boggio dei Fratelli di Soledad, Luca Dell'Olio, Gli Atlante ed Emanuele Via e Charlie T Radio Ugi si evolve e diventa il mezzo per stare vicino ai piccoli degenti dell'Oncoematologia Pediatrica dell'Ospedale Regina Margherita: nuovi format verranno creati per aiutare tutti a fuggire dall'isolamento. Così facendo chiama tutte le associazioni operanti all'interno dell'Ospedale Regina Margherita di Torino per una nuova serie di Appuntamenti! Condividi la diretta e interagisci con noi sui social! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.it
This week we are joined by Mr James Ramus, otherwise known as Jim!Mr James Ramus is a substantive consultant surgeon at the Royal Berkshire Hospital. He was appointed in May 2012 as member of the UGI surgical team to help develop the Bariatric Surgical Unit (Berkshire Weight Loss) and is now part of Opitmise Weight Loss.He is a fully qualified General and Upper GI surgeon specialising in laparoscopic (keyhole) surgery for gallbladders, gastro-oesophageal reflux, hernias and weight loss.A fascinating listen, delving in deeper into the subject of weight loss surgery.
Apologies for the sound quality, as I was also recording for the YouTube channel. Special episode, due to a leaking washing machine and time constraints I did the podcsast and the youtube together. So, check this out on youtbe as well!! We discussed the first dividend paid in 1602, the biggest single dividend I could find, 14 companies with 100+ years of dividends and my buys, sells and dividends received. Tickers mentioned in this episode ALB, KMB, PEP, MRK, SIX, BP, LMT, GPC, CB, T, KO, CHD, PPG, GIS, CL, SWK, PG, JCI, ED, LLY, UGI, XOM, YORW & DPS. Full Disclosure - I am long ALB, KMB, PEP, MRK, LMT, GPC, CB, T, KO, PG, ED & XOM. Disclaimer - I am not a licensed financial adviser and none of this is financial advice. These are my thoughts and opinions shared for fun and entertainment!
Semantik & Steezo laden monatlich, illustre Gäste aus der urbanen Szene, zu Kaffee und Kuchen ein, um über Gott und Hip Hop zu sprechen. In dieser #CornerTalk Folge werden Blumen an Ugur Gültekin und Lukie Wyniger verteilt, zwei Urgesteine in der Schweizer Medienlandschaft. Lukie erzählt von seinen Rastas in den 90er, seine tiefe Leidenschaft für die Musik und das ganze Background Buissnes, seine Konfrontation mit Gimma und über seinen momentanen Lieblingsartisten „Pronto“. Ugi zeigt sich ebenfalls sehr kommunikativ und geht zurück in die Zeit als er selber noch aktiver Rapper der X-Chaibe und stolzes Mitglied der Bauers-Familie war. Über die Bounce Cypher Konstellation an den SMAs wurde debattiert und für den momentanen Stand und Erfolgsmassstab der CH Rap Szene, Wissen und Hoffnung gespreadet. Viel Spass bei dieser sehr offenen und realen Ausgabe!
This episode introduces us to oesophageal (or esophageal for our North American friends) cancer. We take a look at both adenocarcinoma and SCC in more detail. Including risk factors, presentation, workup, management, follow-up and prognosis.Keep an eye out for next week's episode where we will be joined by an UGI surgeon to answer some of the burning questions that come up in this episode!DisclaimerThe information in this podcast is intended as a revision aid for the purposes of the General Surgery Fellowship Exam.This information is not to be considered to include any recommendations or medical advice by the author or publisher or any other person. The listener should conduct and rely upon their own independent analysis of the information in this document.The author provides no guarantees or assurances in relation to any connection between the content of this podcast and the general surgical fellowship exam. No responsibility or liability is accepted by the author in relation to the performance of any person in the exam. This podcast is not a substitute for candidates undertaking their own preparations for the exam.To the maximum extent permitted by law, no responsibility or liability is accepted by the author or publisher or any other person as to the adequacy, accuracy, correctness, completeness or reasonableness of this information, including any statements or information provided by third parties and reproduced or referred to in this document. To the maximum extent permitted by law, no responsibility for any errors in or omissions from this document, whether arising out of negligence or otherwise, is accepted.The information contained in this podcast has not been independently verified.© Amanda Nikolic 2020
An interview with Ugljesca Djuric, Head of Content at lemlist. We talk about how he manages linkbuilding and the SEO content strategy of bootstrapped lempire.lempire went from 0 to $1M in ARR in under 2 years, with no funding. Find out how content played a huge role in that and how to model your own linkbuilding strategy for your own startup.Connect with Ugi on LinkedIn: https://www.linkedin.com/in/ugljesadj/
Core Questions Define upper gastrointestinal versus lower gastrointestinal bleeding and differentiate between the two based on anatomic location Outline an approach to the history and physical examination for the patient with complaints consistent with GIB.- Box 27.3 List 5 causes of UGI bleeding and 5 causes of LGI bleeding- Table 27.1 Outline six alternative diagnoses or mimics of GI bleeding - Box 27.1 List five characteristics of patients with high-risk GI bleeds - Box 27.2 Describe an approach to ancillary testing in the patient with GI bleeding. List five substances that when ingested, can result in a falsely-positive stool guaiac study Outline an approach to the management of the patient with GI bleeding - Fig 27.3 Detail the Blatchford and Clinical Rockall Risk Scores - Tables 27.3/27.4 Wisecracks Outline the three most common causes of UGIB in pediatric and adult patients. Outline the three most common causes of LGIB in pediatric and adult patients. What percentage of patients presenting with hematochezia actually have an UGIB? What volume of blood loss is needed to produce symptoms of anemia in the patient with an acute/subacute GI bleed?
Core Questions Define upper gastrointestinal versus lower gastrointestinal bleeding and differentiate between the two based on anatomic location Outline an approach to the history and physical examination for the patient with complaints consistent with GIB.- Box 27.3 List 5 causes of UGI bleeding and 5 causes of LGI bleeding- Table 27.1 Outline six alternative diagnoses or mimics of GI bleeding - Box 27.1 List five characteristics of patients with high-risk GI bleeds - Box 27.2 Describe an approach to ancillary testing in the patient with GI bleeding. List five substances that when ingested, can result in a falsely-positive stool guaiac study Outline an approach to the management of the patient with GI bleeding - Fig 27.3 Detail the Blatchford and Clinical Rockall Risk Scores - Tables 27.3/27.4 Wisecracks Outline the three most common causes of UGIB in pediatric and adult patients. Outline the three most common causes of LGIB in pediatric and adult patients. What percentage of patients presenting with hematochezia actually have an UGIB? What volume of blood loss is needed to produce symptoms of anemia in the patient with an acute/subacute GI bleed?
For Joseph Kopalek, it was natural to follow in his father’s footsteps and pursue a career in the energy industry. What might appear less natural is the path he took to get there. “He worked his way up from a laborer into management,” Joseph says of his father in this episode of the No Accident podcast, presented by TRUCE. “I took the long route and went to college, played around in environmental consulting for about eight years, and then got into the natural gas industry.”After his consulting work, Joseph spent a large portion of his career in operations management for various energy companies — primarily Columbia Gas Transmission — before realizing that safety was his true passion. So when he was offered his current position of Vice President Environmental, Health and Safety at UGI Utilities, Inc. a little over a year ago, he took it without hesitation. The COO of the Denver, Pennsylvania-based natural gas and electric utility company told him he was perfect for the job because of his operational credibility.“They won't question how you’re perceived or how you set up something from a safety standpoint because they know you know how to get the work done,” he recalls his boss telling him upon promoting him. “You've been there all the way from field supervisor up through director ranks.”Since then, he’s proven his boss right by consistently valuing employee feedback/input and focusing on problem-solving rather than pointing fingers when safety issues arise. Some of his biggest lessons have come from working with Dupont Sustainable Solutions on an improved safety strategy following a fatality that happened within UGI in 2017. “We realized that there were some improvements that needed to be made on how we respond to emergencies — the kind of equipment we use, and we need to preserve life as our first priority,” he said. “One of the things we changed is one of the metrics that we use … that is a make safe time, that's the time it takes to call an employee out .. into the field and making whatever situation they find safe.”And it must be working because UGI has since been recognized by the American Gas Association for having some of the best emergency response times in the industry.Featured Guest
Are you trying to keep up with the latest medical literature but your journals keep getting blown away by the industrial fan you've bought to try and survive this sweaty heat wave? Your ears are in the right place! In this months episode:...Tranexamic acid in UGI bleeding: more harm than good?...(04:35)HALT-IT Trial Collaborators. “Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.” Lancet (London, England) vol. 395,10241 (2020): 1927-1936. doi:10.1016/S0140-6736(20)30848-5...Cocoa beans in acute ischaemic stroke?...(08:15) Modrau, Boris et al. “Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial.” Stroke vol. 51,7 (2020): 1983-1990. ...Ticagrelor for stroke prevention?...(12:40) Johnston, S Claiborne et al. “Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA.” The New England journal of medicine vol. 383,3 (2020): 207-217. ...Probiotics for your mood?... (16:28)Noonan S, Zaveri M, Macaninch E, et al Food & mood: a review of supplementary prebiotic and probiotic interventions in the treatment of anxiety and depression in adults BMJ Nutrition, Prevention & Health 2020...Probiotics in care homes... (22:15)Butler, Christopher C et al. “Effect of Probiotic Use on Antibiotic Administration Among Care Home Residents: A Randomized Clinical Trial.” JAMA vol. 324,1 (2020): 47-56. ...Tofu to reduce mortality?... (25:11)Cai, Xiaoyan et al. “Association between prediabetes and risk of all cause mortality and cardiovascular disease: updated meta-analysis.” BMJ (Clinical research ed.) vol. 370 m2297. 15 Jul. 2020,...Coffee time: the facts and myths... (29:16)van Dam, Rob M et al. “Coffee, Caffeine, and Health.” The New England journal of medicine vol. 383,4 (2020): 369-378....Does MTX actually cause ILD?...(33:15)Juge, Pierre-Antoine et al. “Methotrexate and rheumatoid arthritis associated interstitial lung disease.” The European respiratory journal, 2000337. 9 Jul. 2020, JOURNALBITES (38:13)Vitamin D & diabetes preventionAn app for cardiac arrestNoradrenaline dysregulates the immune responseAI & Skin disease...Putting the Ash in hand wASH...(42:40)-------------------------------------Check out the awesome infographics on Twitter @JournalSpotting or our website
Cerita dari dan dibacakan oleh Ugi (mughnyaz). "Tapi tiba-tiba, ranting itu bergerak ke bawah. Seperti ada sesuatu yang memberatkan ranting itu."
Dr. Mohammed is the Founder and President of ManaGene considered one of the most innovative leaders in the emerging personalized medicine and lifestyle genomics space. In August 2018, ManaGene merged with Youtrients (www.youtrients.me) to form a new company known as The DNA Company. The DNA Company represents the evolution of functional genomics and is focused solely on the optimization of human health and performance. Dr. Mohammed is widely regarded as a pioneer in medical genomics and has been the recipient of multiple academic and industry awards. He is the holder of several patents in the general fields of molecular diagnostics and genomics research and is one of the most sought-after national and international conference speakers in the genre of personalized medical genomics. In this interview, Lisa and Dr. Mansoor dive deep into the power that lies in understanding your unique genes to change the outcome of your health. Some take the fatalistic view that if you have a bad gene or combination of genes you are powerless against them so it's best not to know but nothing could be further from the truth. Understanding your genes through DNA testing is like getting the user manual to your body and learning how best to care and treat it. The granularity with which you can start to understand processes and how these affect you and how you impact these is astounding. This s actionable knowledge that will help you make informed decisions regarding your health in such areas as your hormones, your cardiovascular risk factors, your methylation, your detoxification processes and even your mood and behavior, why for example some have a tendency to more problems around depression or PTSD than others. Never before in the history of the human species have we had such deep insides into the way our intricate and complex bodies work. This episode is set to blow your mind and the work of Dr. Mohammed and his team is set to change the future of the world's health. We have the opportunity for the first time to take control of our own destinies rather than falling victim to our genes through a lack of knowledge. Once you start to see and understand the power of functional genomics you won't be able to go back to the way you understood yourself and your body before. Your level of self-acceptance and the ability to help yourself heal and be healthy and whole will be taken to a whole new level. If you would like to get your hormones or your whole genomic profile tested you can find out more at www.thednacompany.com We would like to thank our sponsors for this show: www.vielight.com Makers of Photobiomodulation devices that stimulate the brains mitocondria, the power houses of your brains energy, through infrared light to optimise your brain function. To get 10% off your order use the code: TAMATI at www.vielight.com For Lisa's New Book Relentless visit the website below to order https://shop.lisatamati.com/products/relentless When extreme endurance athlete, Lisa Tamati, was confronted with the hardest challenge of her life, she fought with everything she had. Her beloved mother, Isobel, had suffered a huge aneurysm and stroke and was left with massive brain damage; she was like a baby in a woman's body. The prognosis was dire. There was very little hope that she would ever have any quality of life again. But Lisa is a fighter and stubborn. She absolutely refused to accept the words of the medical fraternity and instead decided that she was going to get her mother back or die trying. For more information on Lisa Tamati's programs, books and documentaries please visit www.lisatamati.com For Lisa's online run training coaching go to https://www.lisatamati.com/page/runningpage/ Join hundreds of athletes from all over the world and all levels smashing their running goals while staying healthy in mind and body. Lisa's Epigenetics Testing Program https://www.lisatamati.com/page/epigenetics/ Get The User Manual For Your Specific Genes Which foods should you eat, and which ones should you avoid? When, and how often should you be eating? What type of exercise does your body respond best to, and when is it best to exercise? Discover the social interactions that will energize you and uncover your natural gifts and talents. These are just some of the questions you'll uncover the answers to in the Lisa Tamati Epigenetics Testing Program along with many others. There's a good reason why epigenetics is being hailed as the "future of personalized health", as it unlocks the user manual you'll wish you'd been born with! No more guesswork. The program, developed by an international team of independent doctors, researchers, and technology programmers for over 15 years, uses a powerful epigenetics analysis platform informed by 100% evidenced-based medical research. The platform uses over 500 algorithms and 10,000 data points per user, to analyze body measurement and lifestyle stress data, that can all be captured from the comfort of your own home For Lisa's Mental Toughness online course visit: https://www.lisatamati.com/page/mindsetuniversity/ Developmental strength, emotional resilience, leadership skills and a never quit mentality - Helping you to reach your full potential and break free of those limiting beliefs. For Lisa's free weekly Podcast "Pushing the Limits" subscribe on iTunes or your favorite podcast app or visit the website https://www.lisatamati.com/page/podcast/ Transcript of the Podcast Speaker 1: (00:01) Welcome to pushing the limits, the show that helps you reach your full potential with your host, Lisa Tamati, brought to you by Lisatamati.com Speaker 2: (00:13) Hey team. We're this week I have an absolutely superstar, the world's number one leading functional genomic specialists, Dr. Mohammed from Toronto and Canada. Dr Mansoor, Mohammed has two guests now. He is a scientist and entrepreneur in the field of genomics and is regarded as one of the most innovative leaders in the emerging personalized medicine and lifestyle genomic space. Dr Mohammed is a PhD and president and scientific officer at the DNA company and is really considered to be a pioneer medical genomics. He's a classically trained molecular immunologist who has received academic and industry awards, published numerous papers and holds patients in the general fields of molecular diagnostics in genomics. Now functional genomics is about understanding the DNA and how it behaves in every definition and this Dr. Mentor was very different than many of the other DNA companies that I've looked at recently and that he doesn't just look at the single litters, if you like, of the DNA, but it looks in combinations of genes. Speaker 2: (01:22) And how they're playing out. And this makes him very, very different. This, he sees DNA like a language rather than a vocabulary and language that has grammar, sentence structure, Syntex and nuances. And you've got to be able to read genetic structure at the holistic level. Now I'm super excited about document's all his work and I'm studying functional genomics at the moment and it is the next level in personalized health. I'm really, really excited to bring this interview to you. It's taken me months to get documents or on this podcast and I'm hoping later on the year to get Dr. Mansoor Down to New Zealand for a lecture tour to speak to functional medicine practitioners down here as well as the public. So if you'd like to know more about that, please reach out to me and let me know. I'm just like to remind you before I hand over to Dr. Mansoor that my book launch is happening just next week over the time of this recording is the 6th of March and on the 11th of March. Speaker 2: (02:26) So by the time this recording actually comes out, my book will be live. It's called relentless and it tells the story of bringing my mum back after a major aneurism myth. You're fighting for a life and lift her in and basically not much over a vegetative state. Massive brain damage at the age of 64 and what I did to beat all the odds and bringing my mum back to health, all of the CRPS I used, the protocols, the attitude, the mindset, the obstacles that we had to overcome, the problems that I've discovered in our medical system in on it goes. So this book is really, I'm, I'm so pleased to be able to bring it out. It's taken me two years to get this together and to bring it to the public, but I really want to pay it forward and I want to help thousands and thousands of other people facing difficult challenges to take them are hit on with the right mindset to overcome great obstacles. Speaker 2: (03:18) So if you'd like to check that out, we can head over to my website. I have Lisatamati.com Hit the shop button and you'll see all of my books there and my jewelry collections. But make sure you check out the neatness. It's really going to be worth a read for anyone who has major medical problems at the moment. Or of course anyone who has a stroke aneurysm Alzheimer's dementia, and wants to know about brain rehabilitation or optimizing your brain function and who isn't interested in that as well as the whole mental attitude and mindset that it takes to do all this. So without further ado, over to Dr. Mansoor Mohammed. Well, hi everybody. Lisa Tamati here at pushing the limits. It's fantastic to have you back again. Now I am just grinning from ear to ear. I can't stop smiling because I've been waiting for this interview for weeks. I have a very, very special guest, Dr. Mansoor Mohammed, all the way from Toronto in Canada. Dr. Mansoor How are you going? Speaker 3: (04:17) I am great, Lisa. And likewise, it's been something that I've been looking forward to, to the audience. Please forgive me. I'm a little bit sleepy from Jeff blog from last night, but Lisa has been pumping me up and so we're going to have some fun of this Speaker 2: (04:31) Now. I know what it's like when you're a little bit jetlagged and you have a main very much in demand. So I'm just so excited to have a little bit of time with you now. Dr Mansoor, I do the whole introduction on a separate recording, but dr Mansoor, can you give us a little bit of background about your what you did your PhD in your, your, a little bit of a brief history of your back. Speaker 3: (04:55) Sure. genes. Genetics has always have always been my love. The study of how this operating manual, just just thinking, just, just dialing it back and thinking that the human being, we've got this operating manual that by every definition of the word it behaves like an operating manual. And to think that it's there and to think that one date might be accessible and that we could read this and we could read it intelligently and just simply understand myself much less, much less. Anyone else has always been my love. And so I started, my PhD is in applied molecular genetics and immunology. So I was looking at the genetics of the immune system. I was very, very fortunate to have an awesome mentor. She was then the chair of molecular biology at UCLA invited me to UCLA. So I had an awesome couple of postdocs there where I got deeper and deeper involved in eugenics. Speaker 3: (05:47) But a real pivotal point happened when I was done, invited to come to Baylor college of medicine and Houston, Texas. And it was that heavy time just about the human genome project, its, you know, sort of pinnacle. And I was asked because of the work that I had been doing with UCLA to come over to Baylor and start a company, the goal of this company was to begin looking at multiplex genomics. In other words, to really do the, you know, the barrage searches into the human genome. Not one gene at a time, but looking at the entire genome in pathway type manners. Now initially we applied this knowledge to cancers. We apply this knowledge to developmental disorders syndromes, Prader, Willi syndrome, autistic spectrum disorders and so on and so forth. And about 15 years ago, after many years of doing what I call disease genomics, looking at the operating manual, looking at when the operating money was broken out of what happens from a disease perspective. Speaker 3: (06:45) Then I sort of thought, okay, well that was fun. That was good. That was, but why should I not look at the operating manual? But nothing is purportedly broken, but just the operating manual. So then still we can tell presumptively healthy individuals how to stay healthy or how to get over the type of chronic illnesses. So this is what I've been doing for the last 15 years, studying, researching and applying the knowledge of the human genomic operating manual. So we've been, we can just simply understand it. How does the body work, which clearly there's an individuality to that, obviously. I mean, we are human beings. We all, our cells, our organs, our bodies, all have to accomplish the same jobs that we do. These jobs with nuance differences, some of us less optimal, more optimal, more efficient, less efficient. And when we can zone into that, when we can read this operating manual from that perspective, really Lisa miracles happened with the sort of insights that you get, the nuances that you can tease out. It really has transformed the clinicians. We train the patients, we work with the transforms, it empowers the individual to understand how their body works and what they might do to obtain that optimal health. Speaker 2: (07:59) This is, and this is a super exciting and I can feel your passion coming through despite the jet lag for this area and it's now mind you, passion is of the last maybe two months or six weeks or however long it is now that I've been diving into this world and just going, Oh my gosh. Oh my gosh, this is just, this is just the next level and the information that I've been searching for to try to understand because everything seems so generic. And this a personalized house and yeah, doctor man saw you the president and founder of the DNA company, which is offering direct to public and in conjunction with conditions. A couple of reports. So our full genomic report in a hormone report and I want to tease apart a little bit today, why should people even consider having a look at these, the sort of testing what benefits they can get out of it. Speaker 2: (08:58) And I'd like to also tease a little bit about looking at other, like I've, I've looked at a lot of gene companies and that do gene DNA testing. And you had an analogy on a Bulletproof radio that I heard you on the same show who's amazing Dave and his work that was about the most people are looking at it DNA as a vocabulary and not a language. And that just seems them light bulb up in my head where I realized, okay, so it's not the siloed genes looking at them individually, but looking at cascades and pathways and combinations of genes as we are then interpretation has been missing today. Speaker 3: (09:43) Oh, 100%. So I always say, you know, Lisa, anyone that is in the data business, regardless of whatever data you're collecting, data is really quite dumb. Data in and of itself doesn't mean anything unless you know what to ask of the data unless you know how to triage, how to approach the data. So when we use the analogy as DNA, the operating manual, the genome, it really meets all the classifications and descriptions of a language. Thus far we've been looking at DNA and genetics from a language perspective purely as a vocabulary exercise. The more words we know, the better we presume to think we know the language. And as much as that is important as per the analogy that I drew with on Dave, show a person simply knowing more vocabulary by no means mean they understand the language. And so when it comes to DNA, when it comes to genetics, when it comes to how this awesome operating manual, the architecture of it, it's not just about vocabulary, it's not just about the individual genes. Speaker 3: (10:51) So here are the two layers implicit in your question that we do a bit differently and why we need to do that differently and why it's important that it's done this way. The first is this. When you're looking at the DNA, if the person are either genetic makeup, the vast, vast majority of companies right now, they're looking at things called snips, single nucleotide polymorphisms. In other words, they're looking at places which is absolutely important. They're looking at spelling variations in this operating manual. And of course these spelling variations, these single nucleotide polymorphisms will impart to you mean Jane, Paul, Peter, the same cellular job that we all want to do. These spelling differences can impact the efficiency with which we do that job and that is important to know, but while we're at that point of spelling, you see per any language, if I wrote a paragraph, I might have spelling errors in that paragraph, but there are examples where I may have inadvertently deleted a sentence or deleted a couple of sentences in that paragraph. Speaker 3: (12:00) Now, if the analogy here is that the gene is the paragraph, so your operating manual are these 23 volumes. Think of it. Think of a 23 volume and psychopathic set these awesome, huge volumes. Now we're going to inherit two of these 23 volumes. One from mom, one from dad, and these volumes are properly arranged and when we open up any page, let's say we go to volume three from mum volume three from dad, we open up page four on each of those volumes and we look at paragraph five page four, volume three we, I see the same paragraph. We're going to see the same information from dad's gene paragraphs of genes and mom's gene. We're going to see the same information, but when we look really carefully, when we look at those paragraphs, really collect carefully, we might find that there's some spelling differences. Those are the snips. Speaker 3: (12:57) We may also find that on either dad or mom's paragraph, a sentence was missing and I just taught this over the weekend. So I was in the auditorium and I said, okay, here's an instruction that was waiting for me coming to this auditorium to give this lecture, Dr Mansoor, go to auditorium B and to the left door approach to podium from the right side, press the enter button, begin your lecture. That's an instruction. That's a paragraph. That's an instruction and that's the equivalent of a gene. Now in that paragraph they make has been a few spelling errors or changes that may have confused me a little as to what the instructions are. But when I look at it carefully, I could sort of still figure it out. Okay. But if in that paragraph, the sentence that says go to auditorium B was missing at, of course there are multiple auditoriums, all of the other parts of the instructions are there. Speaker 3: (14:03) But I can really be confused as to what is the ultimate thing that I'm supposed to do. It's called an indel. So in our genes, not only do our genes have slips, many important genes actually have places within them that I'm missing. So until we test for those type of changes, we're by no means getting the full picture of what is happening. The third thing is this, not only do we have slips, not only do we have in Dells, there are occasions where the entire gene is missing is show I'm supposed to show up. I got to the hotel where the conferences are and the instruction just telling me what it's just not even there. So here I'm in the lobby going, I don't know what I'm supposed to do. This example is a genetic phenomenon keeping the analogy, this is called this C and V copy number variation. Speaker 3: (15:03) We see because we were supposed to have two copies of that. Paragraph five page four, volume three. Sometimes believe it or not, when we go to page four we've opened up mum's volume three dad's volume three. There they are. We're going to read both of the instructions cause that's what yourself has to do at any given moment. When there's a job to be done, your cell goes and pulls the volume that has that instruction, takes down a mum's copy, takes down, dad's copy, opens up and reads the instruction. Now in the case of a CMV copying of the variation, we can open up mum's volume three page four there is paragraph one, paragraph two, paragraph three paragraph four paragraph six. Oops, wait a minute. Where's part of our five? It's gone. There's part of four. There's part of six. I look over a dad. He's got all of the paragraphs or vice versa. Speaker 3: (16:02) Sometimes Lisa, both paragraph fives are gone. Okay. So the point of the first answer to your question, why we do things a bit differently is we're not just in the business of collecting data for data's sake. We're collecting data. Are you were doing gene testing to understand a process. When we designed genetic tests, we don't begin with genes. We begin in a whiteboard saying, what is the thing in the human body that we want to study? What is the thing that we want to study? Genetics, just good old fashioned medical textbook, human physiology. Do we want to study the way the newer chemicals are produced and bonding and response? Do we want to study how the human body makes sex hormones? Something we should talk about when it comes to human performance. So how does the male and female body makes progesterones androgens Astros? And then we mapped that out. Speaker 3: (16:56) Forget genetics, which is not about how does the human body do that? No, of course, if the human body's having to do something, then it means there are genetic instructions for that film. So only when we map out the cellular, the cellular biology, the cascade, only when we met that out, then we come in and we pencil it. This gene is responsible for here. This gene is responsible for there such that at the end of the exercise, we've got a genetic test that already tells a story. The result from that genetic test is telling you the entire cascade. Step one, step two. We look at each of those genes that are telling us the story and we ask are these snips that are important? Are there entails that are important? Are the CNVs that are important because all three make a wow. And so the first part to the answer to your question is if you've been looking at genetic tests that are only reporting snips, you are dramatically limiting the variations that you and I and every other person have within our genome. So you're missing the nuances that are in your language to clarify the job to be done. Does that make sense? Speaker 2: (18:16) Absolutely. So that actually puts them together in my head because I've been starting this, I don't know, like for example, the GSTT one gene and the detox and antioxidant pathway, one of those types of genes that can be completely done. Speaker 3: (18:31) Completely. Totally said, absolutely. And of course it belongs to super family. So there are multiple G S T genes, but two minutes on that. If you're going to design the human body and you're going to say, listen, one day we're going to make this thing called human being and we're going to put him or her in this wonderful world, but mind you, he or she is going to have to deal with some toxic insults, both from without and from within. Where would you, and you know that, where would you put your detox defenses? Well, they're about four places. If you're an intelligent designer, you would put your detox, different defenses at least in four places. You would say, how and where do things get into the human body, dermal skin, the nose, nasal Bronxville lung, the GI track. Okay. So those are how things get it. Speaker 3: (19:23) And unsurprisingly you would want to make sure your detox genes and the things that you'd want to make sure there's super active in those places. And then you, you'd also say, well look, at the end of the day, things are always going to get past borders inside of the body, their waste products. So then I'm also going to put a detox organ. The liver, when we go to the human body, this is where we find these detox genes expressing themselves. And each of the GST is have sub specialties. Some of them are more important in the nasal bronchial track, some of them more important in the GI track and so on and so forth. So when you know the story that you want to read about the body, you know how to read the manual and interpret, is the GST T one gene deleted or not? This is a massive implication to the human body. Speaker 3: (20:16) Can you imagine the GSTT one gene is one of, if not the most important bio transforming antioxidizing enzymes in the body per its name and its gene and its enzyme. And if a person doesn't have it, literally it's not in mere manual. The GSTT one gene is on volume 22 and if that paragraph you have not inherited it from either mum or dad, you are missing an enzyme in your body. That is one of the most important detox. Now doesn't mean that you're not compatible with life, but it most certainly means you could not be the person who says, well you know what do you have a metals mean after all they're not that bad. Oh you know what, my uncle smoked until he was 80 years old. I'm going to smoke as well. Well you can't compare yourself to that person cause you don't have one of the most awesome detox genes. Speaker 2: (21:13) You don't have a good defense mechanism. And so like the detox is actually the first port of call before the immune system even does this job. So I'm, I'm excited to get my tests back cause I haven't gotten gotten through the reports yet. I'm, I'm suspecting that I have a problem in my GC jeans because I'm a very young age. For example, I've been the next medic as a, as a severe asthmatic, as a child, and I'm very hypersensitive to smells and anything. So I'm like a Canary one C one, which is theta. Yes, Speaker 3: (21:54) Very important in the liver. Key one PI GSTP one is the one that's really important in your nasal bronchiolar lung cavity. Individuals with a suboptimal P one are at extreme risk of early ectopic asthmas. They're the ones that if they go into the shopping mall, you know, the perfume resection, they've got to avoid the perfume resection. Right? Those are the GSTP ones. Speaker 2: (22:21) Wow. I'm obey. Fascinating to see if that's what comes back. And so if you want it deleted into them, we'll get onto hormones next because I really want to dive into there, but just to, to to look at the GST genes. If you don't have, you either have only one inherited GST, one gene, your mother or your father and you're missing the other ones or you're missing both altogether, are you more likely to have you're more likely to have toxins coming in that you can't deal with as well. And then your immune system is this way or auto-immune or part of the Speaker 3: (22:57) Brilliant, brilliant question. Just before we answer that, I had mentioned there were two layers to differentiate yourself, so just so that we close the chapter on what we do differently. So I'm going to come back and, and so now we will take it forward. We just mentioned that there you have to be mindful of the three different layers of variations, snips in Dalles with pieces of the genome missing and CNVs where the whole gene may be missing. The other quick differentiator, bringing back the analogy of a language, bringing back the story of the human body, it's this, and I told the audience this, there was an audience of clinicians in Phoenix this weekend. I said, have you ever read a really good, you know, suspense novel and not suspense novel, the novel that the author's painting the character and you're thinking he's the bad guy, you know, and he's falling around the heroin and he knows he looks a bit shady. Speaker 3: (23:51) And then until or unless you've read the entire book, you only find out that he was a protector or he was something. He was a guardian and words. He wasn't about that guy. Now what the heck does this have to do with genes? The second player, when we mentioned that we do things differently, we said that DNA is really a language by all of its definitions, with its nuances is this, there are many genes, Lisa, where if you were to look at that gene as a standalone and if you was to look at the genotype of that gene, in other words, what version do you have? You think you have either the best version or the worst version depending, and you may think you have the best version for example, but it is not until you look at a completely independent gene that has nothing to do with this gene, that the version of that independent gene wow colors, whether your actual optimal version of gene a will stay optimal or not. Speaker 3: (24:52) Or conversely, whether you thought you had the suboptimal version of a bad guy, you read the full story, something else tells you what you fought was the bad guy was not the bad guy. Wow. And this is what it's called at peace basis. You see we're all concerned about epigenetics, which is important. FP genetics. How are we reading? Are we actually going to read that paragraph on the page or are we not going to read? That's at the genetics, but nobody's talking about epi. Stacy, this is Stacy. This is often, we've read the page after we've read the paragraph. We cannot yet make a conclusion until we read 10 pages later, 15 pages later, something there. We'll bring it to life. We'll color what we read on page three. Speaker 2: (25:48) Yeah, so, so for example, if you're, if you're looking at a specific gene and it has an, that is say the faster for the sip, 79A1 gene and the hormone a kiss guide. If it's a fast one that's not in and of itself a good or a bad thing. It depends on the other things. It depends on the, so that's what you're meaning. So one of Speaker 3: (26:14) The best examples of that is this, the BDNF gene, the BDNF gene, brain derived neurotrophic factor. What are the most important genes in the brain? Well, in the whole human genome that tells the brain how to secrete this awesome thing that heals the brain. You and I were having a conversation about a loved one, so that loved ones B, D and F was going to be hugely important. And how that loved one recuperated from the challenge that she had met BDNF. Now the beating of gene has an important variation. A snip this time, which is either a G version or a version. Okay. TheG version, Jews and George as in guanine is the optimal version of BDNF, the optimal version. So if you're a GG blessed, that's good. You are naturally predisposed. You have the in Harrods, the innate ability to make more BDNF. Speaker 3: (27:13) And let me tell you that's a good thing. Any which way you slice it. Wow. An independent gene, the TPH to gene the trip to five hydroxylase gene to TPH, two gene, which is involved in how the body deals with serotonin. K two has a sip. It comes in a G version and a T version G as in George T as in Thomas. The G version is considered optimal but hold on. If you happen to be GG fatigue, pH two and GG for BDNF ostensively both those genotypes for each affair genes are optimal, but if you were GG for both, it creates a haplotype. It creates a combination that is an act risk combination and it is, it is the negative combination. It is the, it is the deleterious combination when it comes to certain aspects of human behavior. These individuals, when you're GGGG, they exhibit poor inhibition of negative emotional stimuli. Speaker 3: (28:28) In other words, when something negatively emotionally affects them, their ability to kinship, the ability to say, you know what, I'm not going to focus. I'm not going to hamster wheel constantly play that over and over over again. They haven't, they have a hard time giving up that when something gets under their skin. So to speak emotionally, they have a really hard time getting over it so they have a strong imprint. The memory imprint, very strong EMI, emotional memory imprint and of course the stronger you EMI emotionally memory imprints, the easier you emotional memory recall EMR is because the deeper something is imprinted then the smallest cue. You have a love, you have a partner and you know you love each other to bits, but like human beings, you're going to have your ups and downs. I mean it's where human beings after all, and on one particular evening you were both getting on each other's nerves and she was wearing that beautiful red dress and that was the evening that you both said things you shouldn't have said and it hurts the person who has this phenomena. Speaker 3: (29:36) Whenever he sees his wife, would that red dress down the road, everything's perfect. You, you're going up for a birthday party, you're both happy, it rises back up. He remembers that evening more than he should. It brings back to the surface and vice versa. This is that Paul, inhibition of negative emotional stimuli that lead to profound memory imprinting and therefore profound memory. Recall. The point of all of this and the reason I mentioned this is, and we're going to come back to the GSTT one, was to clarify, you see Lisa, it's not just about even the type of things you're looking for. What matters is the interpretation we sell the combination, we are reading the manual, not just flipping, picking words out. Speaker 2: (30:24) This is we have a calmer is well we are the, the apostrophes are this is someone that is what they would be more prone to PTSD Speaker 3: (30:36) 100 that's the point actually and that is further exacerbated based on the no adrenergic pathway which dramatically increases the risk of PTSD. It is exacerbated based on how quickly they are removing their dopamine and noradrenaline via content. So what happens is you begin to pixelate a picture and you've got a low resolution picture and then the more intelligence information you put in, you start to increase the resolution of that picture. You start to get a clearer picture of the person that you're looking at. But to do so, you've got to know where to pick slate. If I'm trying to get a better look at what Lisa's face look like, I don't really be pixelating your toes. I need to pick slick your face and this, this ability to read intelligently. Lisa, I stress intelligently. Riyadh, human genome. Yeah, that's what we do. We do Speaker 2: (31:35) That is absolutely insane. And they've vacations because yeah, I would have seen, Oh, you've got a G G G is good, but I've just understood that nuance, that combination of things. And now I can't wait to get my reports and my family reports so I could because this helps us also understand like the speed in which you are dopamine is processed and gotten rid off or the speed of which we're saratonin tone and all of these things have a fixed on your personality and that we're not 100% to blame for some of our differences. Speaker 3: (32:12) Oh gosh, no. Gosh, no. In fact, what this needs to do on the one hand, it creates the empathy of appreciating, look, this is how some of this is their predisposition. Now, on the other hand, it is not to create a sense of fatalism. While that's the way I am, I know I have found and I have done. The only thing that I've done, probably somewhat unique and special Lisa, is I have reviewed thousands upon thousands of profiles. In terms of my in the world, most of my peers that work at the level I do would say Dr. Mansoor Probably reviewed the most genomic profiles in the world. I don't know if that's true or not, but I certainly have reviewed several thousand meaning meeting the patient, speaking with their doctor, looking at their health profiles and looking at underlining genetic phenomena to see if we can understand what's going on. Speaker 3: (33:00) You know what I found, at least as a fellow, when you empower a person to understand a predisposition, you, you might think that leads to fatalism, but when you explain the functional reality, it actually does the opposite. It gives the person a sense of ownership and then they can finally say, you know, I have dumped with my entire life, I've been this way and I just, I didn't even know why it was that way. Now that I can even understand what's going on, it gives me some closure. Yes, but it now gives me something to appreciate. I can, I can envision how this is working, how my emotions are working. I can now go, you know what? As soon as I see that stimulus that would have got me on that slippery slope, I'm going to stop. I'm not going to go down that slippery slope because I know if I do, there's no coming back for the next two weeks. Speaker 3: (33:52) So what we've found is that this crew all around it just creates empowerment. Which brings me now to the question that you asked about GSTT one and you are, your connections are on point, Lisa, the connection between the detox mechanism of the body. Here's the threefold, and of course it's a bit more complicated, but it's also remarkable. You can take complex systems, break them down to building blocks and keep the acuity. So there are three building blocks we need to look at when we connect detoxification pathways in the body and the immune system. And the, the only thing missing is the inflammatory system. So the triangulation between toxins and immune responses goes like this. The human body's insulted with whatever. It's insulted with the intentional, the unintentional of our daily lives, those toxins enter the body or they try to enter the body. Step number one, how individually efficient is that person at negating bio transforming, neutralizing those toxins either before they can enter the body, such as in the mucosa of the lung, the alveoli lumen, the the lining of the lung, such as the GI mucosa and so on. Speaker 3: (35:16) And so what can we, can we neutralize it so the toxin doesn't even get into the bloodstream? And of course to the degree that it gets into the bloodstream, can we live a hepatic re detoxified so that at least it does not by you accumulate in the body so that at least it does not reach levels that are unsafe. First step number one now too, there are genes, there are whole gene families, their whole cellular processes, GSTs, glutathione, ionization, UGI, Ts, glucuronidation, methylation, self, phonation and acetylation. These are the major enzymatic steps linked to genetic genes that are responsible for bio transforming neutralizing things in our body, okay? So what we need to do is we say, what is the lifestyle environmental context of the person? What are they getting exposed to? I'll be living in a home that has written with mold, are they living and so on and so forth. Speaker 3: (36:17) Okay, step number one, step number two, how good are they at individually neutralizing those toxins so as to not bio accumulate them to the degree that those, whatever. The answer to that question is we're going to have an individualization and with some individuals are better at getting rid of toxins and others are not. If a person is not genetically, innately efficient, optimal at getting rid of their toxins, then what happens? Well, what do toxins do? Toxins cause cellular inflammation, okay? And they cause inflammation via any number of methodologies. They can inflame cell surface receptors, they can get into the cell and create overproduction of oxidants as they can hamper the energy modules, the mitochondria. That's one of the places you'd never want toxins getting to. And of course they can get into the nuclear eye. They can get into the libraries of the operating manual and they can start to change gene expression. Speaker 3: (37:23) So toxins do all of these things. Ultimately, you see Lisa 15 not even 15 years ago, 10 years ago, if you told that a medical conference, there's this concept of inflammation. You'd have a lot of professionals. Well, come on, you gotta be more specific than that. We actually now know that there is a phenomena called chronic inflammation, and regardless of what stimulated that inflammation, bat bacterial toxin B, it's an inorganic chemical. It be it a physical inflammation. It does not matter the way the sun looks, the way the cell begins to behave when it has been insulted with toxins, with exposures, remarkably is the same regardless of the stimulus. Because chronic inflammation has hallmarks that are similar regardless of the stimulus. Now at that juncture, when the cell is inflamed, when the machinery in the cell isn't doing the job that it's meant to do properly, that cell now starts to be like this pulsing red thing just by analogy. Speaker 3: (38:35) In other words, the body is looking at it going, something's happening in there. It's not behaving the way it should. Okay, so now we're going to have two steps. The body now has an anti inflammatory set of steps to quiet us, to bring the cell back into line cause they Whoa, Whoa, hold on. You're starting to misbehave. There's too much inflammation. This is where it's selling the process known as methylation comes in. Cellular methylation can be viewed. It's a detox reaction by the way, but it is a cellular cascade that is radically responsible for bringing your soul from that humming, inflamed, you know, ticking bomb type of modality back down to acquire essence behavior. That's cellular methylation. Now, to the degree that you're able to do that, because suddenly methylation is a multigene cascade, multiple places where things could be not as optimal as we would like. Speaker 3: (39:36) So to the degree that we then triage, we stratify the patients based on their detox potential. We then stratify them based on their anti inflammatory potential. Now, to the degree that we are not quite yessing that chronic inflammation, this is where the immune system can be activated. Immune system was meant to be activated in acute episodes, not chronic episodes. The more you ask the cell to produce antibodies, IgG, IGA is IGMs, particularly IgGs. The more you keep telling that the body pump out IgG, something's not working right, something is there, which is why chronic infections are now very well understood to be linked to autoimmune diseases. The infection did, did not go away, constantly demanded of the body to produce antibodies. And somewhere along the line those antibodies begin to forget what was the bacteria or what and what was the self. And now we just start shooting friend and foe alike. Wow. This is the triangulation that has become now a focal point of so many diseases. Some diseases being more relevant to the whole, you know, things like lying disease. Do you guys have lung disease down in New Zealand? Speaker 2: (41:05) I think, yes, we do. And I think you know we have a massive problem with like thyroid, Hashimoto's sort of autoimmune diseases, crones, IVs. So this is, this is where the body is actually going in overdrive. So the, the original detox genes haven't been able to do their job because combination. Speaker 3: (41:26) There's that one. Exactly. There's inflammation. Yup. Speaker 2: (41:33) Yes. Speaker 3: (41:33) Methylation didn't do the job that was supposed to do and now we're triggering. So there are meta-analyses meta-analyses that show the deletion of the GSTT one gene or overall poor Ghouta finalization has been strongly linked with ulcerative colitis, Crohn's disease, IBD, strongly linked with ectopic asthma, particularly GSTP one in early childhood asthma. Then of course, if you, if you double down on poor math on poor detoxification with poor methylation, you really start seeing Speaker 2: (42:10) Clinical outcome. Yes. Yeah. So, so if we then we, we, we find out all this about ourselves. We find out we've got either the good or the bad and the ugly. And these combinations are not ideal. Then how, you know, we've got this information now, now we want to know what the heck do I do about this? I can't change my DNA. Of course, all things that these reports that your company does, for example, where it can actually lead to some successful outcomes. Obviously avoiding cigarette smoke or exhaust folk tunes and things your GPS deleted. But, but beyond that, nutraceuticals, new nutrients what can be done to help people. Speaker 3: (42:52) So it starts with, so the first thing I would have to say is we take our reports only so far. So the actual report, we take it to the point of explanation of what's happening. And there are certain recommendations, but the real magic must still come from a trained population, you know? So what, so what we do is through also training a certain class of healthcare providers. We might call them the, the new modern day biohackers. The healthcare providers who are really sniff, they're no longer just, you know, pill pushers. They're looking. So I just wanted to clarify. We take the reports, we explain the systems, we explain what's happening, but we also have to be careful so that people aren't jumping to conclusions and self-treating based. So you still want to have someone who understands the bigger picture. And by the way, that's the second part of what our company does. Speaker 3: (43:47) As per my travel schedule, I'm constantly traveling, teaching people, teaching auditoriums full of doctors who are now saying, listen, if I keep practicing medicine the way that I'm practicing, I'm just dealing with a disease population. I'm not healing people. Okay, so with that minor clarification, now we come to, let me paint a picture, paints a thousand words not to be, you know, blahzay here's what I like people to picture and here's what you would want to picture for yourself. Lisa. Picture slide. Okay, so there's a slide your screen, okay, and a circle. And then picture a circle on that screen somewhere on your screen. There's a circle. Now because you're a human being, your circle is going be on the screen. In other words, this is the screen of all human beings and your circle, you, your circle is somewhere on the screen or what does the circle represents? It represents your genetic makeup, which represents a part of your genetic makeup for whatever biochemical process we were studying. So this circle is Lisa's genomic pathway. Okay. Speaker 3: (44:56) I want you to then think of an equilateral triangle that equal three sided triangle that just perfectly encompasses your circle just perfectly. Your circle is perfectly encompassed just right in that triangle. And the emphases of this triangle are labeled environment, lifestyle and nutrition. Yes. What we're learning and what we're recognizing more and more is other than extreme cases, other than extreme cases, and there are mind you extreme cases where a particular genetic combination was really just a real doozy. And in other words, we're going to see some, you know, with the best of efforts, we're going to see some probably deleterious outcomes. Fair enough. But other than those extreme cases, for the vast majority of us, the spite, any inefficiencies we might have if we find the right triangulation of lifestyle, nutrition and lifestyle, nutrition and environment. If we could figure that out and it perfectly matches, I would circle. Speaker 3: (46:08) This is optimal health. So image, the image of optimal health is when you can find your genomic makeup, your circle for whatever you're studying and contextualize it perfectly within the right for you. For Lisa Laughlin, sir, not for Joanne Felisa. What is leases? Optimal lifestyle, nutrition and environment. Now the problem is, Lisa, when we begin working with a patient, obviously and clinicians with their patients, the vast majority of individuals, they do not know their circle. They don't know what's the economic influence. So they don't, and if you don't know your circle, your triangulation, choices of lifestyle choices, nutrition choices, and environmental choices offers skewed and they are not synergistic with your circle. So first objective of this, did you get that picture? Do you know when people say, well, it depends on your genes, your genes. It depends on how you're using your body. If you are, if you took, if you took five identical individuals, they were, you know, quintuplets identical, contemplative. Speaker 3: (47:27) If such a thing exists in today, the same genes and you give those five people at 35 years old, the exact diet. But if those five, one of them was an ultra marathon runner and extreme sports enthusiasts, the other was a couch potato, I don't know, doing whatever the other was a, you know, an accountant who had a nine to five job. We can exercise worrier, but from Monday through Friday really just goes to work, comes home, eats, goes to that and so on and so forth. Even with the same jeans, you can put the nutrition and an obviously not expect the same outcome because they got to know the genomic legacy. You've got to know what is the lifestyle context, what is the nutritional context, what is the environment or context? If one of the things quintuplets moved from your gorgeous country and move to massive metropolis with, you know, air quality, that breathing for one day is the equivalent of smoking a pack of cigarettes in your beautiful country. Speaker 3: (48:36) He or she may have gotten away with a GSTT one or GSTP, one suboptimal ability. He's living in those, you know, that wonderful country views. He's practicing otherwise good, not eating foods with pesticides and herbicides and so on and so forth. And he was going about life actually, not really realizing there was any suboptimal ability until one day his job took him to a big metropolis somewhere. He lost track of the quality of his foods. He's just so busy. He's day in, day out breathing the equivalent of a pack of cigarettes and then six months into this, all things ELLs as equal, his jeans are equal, but he now starts to show symptomologies that he would never have had any different environment and a nice clean environment. Right? So this triangulation is so important. Now coming back to the specifics, once we understand the pathways, we begin first with the dose. Speaker 3: (49:31) It may seem simple, but it actually enters Lisa into, it's not just about the obvious things that you might imagine. I give the example, Lisa, and by the way, it's relevant to the GSTT one gene. Now, juice, TT. Let's focus on the T one. It's the big sister in the glue, the fine fabric. So GSTT one no, it's what's called a phase two detox pathway. Phase two detox. Because when it talks and enters the human body, we typically go through two steps. We take toxin a, we converted into an intermediate B. Yup. We take B further, convert that to C. C is what leaves the body, the B to C part of the transformation. That's where the GSTs come in. The a to B. This is where your cytochrome P four 50s come in. That's the phase one. Bio transforming enzymes. Now if I were to ask you something, when you say fiber to say, would it be a good practice for person to start drinking a nice cup of green juice? Speaker 3: (50:38) You know, like some juice, juice, broccoli and some maybe put a little bit of a baby spinach in there. A bit of ginger, maybe some cute, cute curcumin at the end of it. Would that be a really healthy drink? Yes. Something I do every day. Beautiful, beautiful. And it is healthy generally speaking. So now someone puts a blog together giving this recipe of something that's ostensibly so healthy and there's this mechanic who works in a shop all day with fuse and so on and so forth. He read this blog, she read this blog and she decides that before she goes to work, she's going to have this beautiful juice. This green juice that they read was so healthy and it was a detox juice and they feel good about themselves. Hold on, hold on. Many of the ingredients and not green juice. Many of the ingredients in that green shoes turn on certain phase one sip four 50 enzymes so as to accelerate the conversion of a to B. Speaker 3: (51:54) Now some of the toxins a that this mechanic was facing in her shop, in the, in the, in the mechanic shop that she was working at, when she converts a to B, we know that the B, the intermediate is truly more toxic than wow. And by the way, she did not know she was a GST one deleted individual. Oh, so what did we do to this young woman? We encourage the things that is that we're getting into her body. When she drove that beautiful healthy green juice, she more rapidly converted her A's into B and then ups B's and to CS very well. Wow. Even something that would ostensibly be really healthy by normal standards. Do you see that's a healthy nutrition on the triangle, but we did not ask what was the environment on the triangle and so now we have skewed her triangle away because her genetics circle, she does not have the GSTT one. Do you get that picture? This is a little bit frightening for people who are listening to this or who might be going well, what's the point being? Speaker 3: (53:16) This is weird. The reports have the super value, isn't it? That's the point. It's, it's actually not discouraging. It's, it's finally, and this is all gold. It's finally meant to unravel those nuances that there is such a thing. Have you been? How many of us, you know, we do something that 20 or the coworkers swore was the best thing since sliced bread and then we tried it and not only did it not work, we actually felt like crap or less healthy, and we, we're all aware of this until it's what is it led? It's led for most of us to become numb. We're just kind of get to that point where we're like, well, I don't know what's right for me or run for me. Plus today it says one thing tomorrow it says another thing. So creating some sanity from this confusion is what this goal is about and it can be done. Speaker 3: (54:11) Lisa, when you take your time to read things, intelligent meals, explain things. That's why we've got these epiphany moments that constantly, I like my consults with patients because I feed off of the energy. When a patient just, you see that epiphany admission and they light up and they go, Oh, that's why this hasn't been working with. That's why that was better for me. That's why I took methyl B12 because everyone's telling me methyl B12 is the best version. But every time I take methyl B is it just in my head. I get a headache every time I take micro B12 I get a, and then I go, no, actually I got one too. I can't take methyl before. That's an actual thing. I can't take methyl B12 because my methylation cascade is inconsistent with me taking methyl Beto when I take a dental Sobe 12. Oh, completely different. Speaker 2: (55:07) Wow. So this is getting really granular for each individual. And this is what makes me so excited. And, but before we go on, we have to go and cover off the hormone report. This is something that I and, and this is, you know, for me and any woman, but I wanted to focus a little bit more in on the woman. We've got very complicated hormones, households, but this was the cascade for men and women is very, very similar, isn't it? Yes Speaker 3: (55:33) It is. It's just remarkably, this is what we taught at the cost on the weekend after introducing genomics, it was the first open to eyes that the cascade, the circadian rhythm with which the human body converts progesterones into androgens, androgens to estrogens, men, we do not have a monopoly over androgens. Women, you do not have a monopoly over estrogens. In fact, your estrogens come from androgens. Men, we have estrogens. It's just a matter of the circadian rhythm. When is it happening? How quickly is it happening? And of course, ultimately how much of any of these hormones are produced. And then the final component is how responsive are you, the the woman's body, all things equal. She's designed with the estrogen receptors to be more responsive to estrogen. She responds to androgens as well. Conversely, for men. Now keep in mind something as simple as, I can't believe how many clinicians do not realize how an androgen or estrogen receptors. Speaker 3: (56:32) Now let's stop there for this cascade. We can talk about all of the things about how hormones are produced and how they're metabolized and so on and so forth. But ultimately, how is estrogen affecting your body? Lisa, you're a young woman. You're making estrogen as if you're menstruating or if you want hormone replacement, there's likely some estrogens in your body, one way or the other when estrogen binds to your estrogen receptor. And to the degree that that can happen, mind you, because there are variations to that fidelity, this complex estrogen. So the estrogen receptor androgen to Stastrom, DHT to the androgen receptor. These complexes are some of the most potent DNA transcribing complex. They go into the nucleus and the churn on genes. This is how estrogen and testosterone impacts the human body. They live. They're not just, I don't know, causing breast development or, or, or, or Andrew demise in the book. Speaker 3: (57:39) They do that by churning on the genes that cause the cells to behave in a more underutilized manner or more estrogen. So the first thing I want, our audience needs, our clinicians, we need to re re climatize reacquaint ourselves with that. These hormones potently DNA transcribing, they go into the nucleus and they turn on and off genes. That is why they are not to be dealt with trivially. Number one. Number two, in a menstruating woman. Now I just told you when estrogen enters a cell, I did binds its receptor. It's not just staying in the, in the Maloo of the South, it's going in to the volts, the nuclear volts and churning on and turning off genes. Wow. When you look at the ministerial cycle of, of a, of a relatively normal, repeatable menstrual cycle, you will notice something radically important over the course of 28 days. Speaker 3: (58:43) The human female body isn't exposed to estrogen at the same amount every day, not at all. The human female body in 20 days only has about a six day or so window in which your estrogens that are really elevated and then it comes down. In other words, what is this telling us from a human biology perspective? It's saying that the type of gene expression changes the epigenetic phenomena that estrogens cause on your operating manual. You don't want that to be consistent and constant across the month, and this is very frightening when you look at contraceptive pill or hormone replacement therapy. So it's most certainly very frightening. That is not, let me be clear. That is not to say that there isn't a place or a time for these things. You know they are absolutely a young woman has to have the right to how she treats her body and what she does. Speaker 3: (59:47) But there is a place in time you at least be equipped, at least be empowered before you make this decision as to a knowing what it's doing for you. Say, okay, look for these few months of my life, for these couple of years of my life, this is going to be a bit more important that I take these precautions, for example, but you should know that to do so indefinitely, month after month, year after year. Now they've got clinicians encouraging young woman not to even have a bleed through. There's no point for even the bleed. So just stay on the, you know, constant level, 24 seven three 65 15 years. How is this compatible with normal human physiology? When you understood what I just said? Yep. Now let's go a step further than that. You see estrogens do what we just said. They bind their receptors, they go into the cell so they go into the nucleus. Speaker 3: (01:00:47) They change gene expression as they're meant to for brief periods during the month. Fair enough. Now, once those estrogens have done what they've done for those days, then the point of it is there's a circadian rhythm. The body breaks down those estrogens metabolizes them by a transforms them so that they're no longer active. They've been neutralized, and then we hit repeat, rinse and repeat, and we start a new cycle. But here's the point. Every a woman, Lisa, every a woman, a man for that matter, but let's focus on the ladies when she made her estrogens or she took her estrogens, because even whether you take it or whether you make it innately or you take it, it doesn't matter. You've got to metabolize the estrogen. Now, every young woman can metabolize estrogens into three byproducts. I estrogen 400 Z estrogen, 16 hours for hydroxy estrogen. Every human being does this, and this is a crucial point. Speaker 3: (01:01:49) Absolutely. But these three metabolites do not impact yourselves in the same way you say. If you thought of it, you've made the estrogen small window. Now you want to neutralize it so that the body isn't under its constant influence. So you want this metabolite, this estrogen, this hub light to have lost bind to the receptor. You want it to last. It's estrogen Ising properties. Lo and behold, four estrogen, one of those three metabolites retains the ability to bind the estrogen receptor. In fact, some studies show it might be an even more potent comm when it, when it binds and it creates this, this common, a tutorial, Leiden and receptor, it's DNA. Transcribing effects are even more potent, much like the analogy between DHT and the androgen receptor versus testosterone. DHT dihydrotestosterone, which is a metabolite of testosterone, has a higher potency binding affinity to the androgen receptor. Speaker 3: (01:03:00) Four hydroxy estrogen is to the estrogen receptor as DHT is to the androgen receptor. Wow. The ability innate tendency of a young woman when she's faced with estrogens to make either the two hydroxy which is considered protective because has lost or the four hydroxy that inmate differentiation is radically genetically determinable. Now, if something as simple as that, Lisa, when you stitch these things together, when you understand, look, estrogen should be my body needs security and rhythm. I do not want estrogen is constant. When I break down those estrogens, I want my body to have had a break from them. And you did not know whether you were four hydroxy dominant or not. If you had a tendency to make more of the four hydroxy than the two and why is four hydroxy so naughty? Three reasons. A, it binds the estrogen receptor, not giving your body a break from the estrogen ization one to four hydroxy estrogen if you are not flushing it out of the body and how do you flush out for drugs, the estrogen through methylation, the comp gene, which is catechal methyl transfers an oops. Speaker 3: (01:04:29) Can you imagine if you were innately genetic info, hydroxy dominant and have the slow comps because now you're making too much four hydroxyestrone you have a tendency to do so. You do not have the enzymatic ability to get rid of it. Now you buy your stagnate, your four hydroxy Astrid. Do you know what full hydroxy estrogen does other than binding the estrogen receptor and Quinones? Quinones? Listen, my God, you're speaking more than some of the best medical biologists that I've spoken to. So the, the decompose into Quinones and do you know what Quinones do? They get into your DNA. They stick to, they are mutagens. They stick to your DNA, causing the DNA to not be able to unravel and repair itself and by the Quinones then cause accidents. So here's what you don't want to be. You don't want to be the young woman who is genetically predisposed to overly produce four hydroxy estrogen simultaneously, have a poor comp, simultaneously, have a low GSTT one GSTP one, which was the thing, Quinones, and then have a poor mitochondrial superoxide dismutase or antioxidation to get rid of the oxidants Speaker 2: (01:05:52) And add to that. You're in your forties or your 50s and you're making more EstroZen, Speaker 3: (01:05:57) Which is a breast tissue because it's not in the liver anymore. The liver organ, at least it was designed for that type of metabolism. You're doing this in the breasts, you know, God forbid. Okay, Speaker 2: (01:06:10) This is where the cancers can come in Speaker 3: (01:06:13) This is weird and just why we have the the epidemiologic rise during that shift where the woman's body shifts from doing that grunt work in her liver, which was designed for it to doing that grunt work in such as breast tissue, cervical tissue, an ovarian tissue and so on and so forth. Which of course the human body, the female body does not express estrogen receptors, the same level for every cell type. You know, when you were, we lobby at nine years old and you could have gone outside, you know, flat chested like any other boy and you know, and then when, when men awe kits and the body changed your elbows and forms didn't change, it was suitable zone. Those are the zones that have more estrogen receptors. Speaker 2: (01:07:03) And this is so this is how we can see like when you're looking at the phenotype, if we can go look like the the the hormone cascade just for people that are listening, it's going from producer owns and pregnenolone's into testosterone's which can sometimes go into DHT and which then go into the estrogen. Is thrown in your estradiol if you're pregnant when you're older you have more strokes coming in which are, that's coming from the the other top of testosterone isn't it? One on one and then it's means a lighter than these three path rates into the two hydroxy four h
Riusciranno i nostri ospiti a vincere gli Ugini d'oro? Ugi nel Pallone è il programma radiofonico che ti permette di vedere lo sport attraverso gli occhi dei ragazzi e dei volontari di Casa Ugi. Commenti, ospiti, notizie e tante risate sono gli ingredienti che cucineremo ogni domenica per voi. Seguici per scoprire le ultime novità dal mondo del calcio e dello sport. Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Intervista alla nostra Veronica, colei che canta e apre le partite dei Giaguari di Torino. Ugi nel Pallone è il programma radiofonico che ti permette di vedere lo sport attraverso gli occhi dei ragazzi e dei volontari di Casa Ugi. Commenti, ospiti, notizie e tante risate sono gli ingredienti che cucineremo ogni domenica per voi. Seguici per scoprire le ultime novità dal mondo del calcio e dello sport. Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
We discuss high-yield topics related to the esophagus, to include: esophageal perforation, motility disorders, diverticula, Barrett's esophagus, and esophageal cancer.
Nerder Things il primo format di Radio Ugi che affronta il mondo dell'irreale e del surreale per scoprirne gli arcani segreti in salsa nerd! Gli ingredienti? Serie tv, film, fumetti, supereroi e videogames, il tutto con la giusta proporzione di simpatia e divertimento. Una "real nerd" e un "nerd 2.0" sono i nostalgici conduttori di questo programma, che vi stupirà e incuriosirà con argomenti nuovi ed inverosimili. Stay Nerd, stay Ugi! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori Informazioni e Collaborazioni Scrivi a radiougi@ugitorino.org www.ugi-torino.org
Ugi nel Pallone è il programma radiofonico che ti permette di vedere lo sport attraverso gli occhi dei ragazzi e dei volontari di Casa Ugi. Commenti, ospiti, notizie e tante risate sono gli ingredienti che cucineremo ogni domenica per voi. Seguici per scoprire le ultime novità dal mondo del calcio e dello sport. Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Nerder Things il primo format di Radio Ugi che affronta il mondo dell'irreale e del surreale per scoprirne gli arcani segreti in salsa nerd! Gli ingredienti? Serie tv, film, fumetti, supereroi e videogames, il tutto con la giusta proporzione di simpatia e divertimento. Una "real nerd" e un "nerd 2.0" sono i nostalgici conduttori di questo programma, che vi stupirà e incuriosirà con argomenti nuovi ed inverosimili. Stay Nerd, stay Ugi! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori Informazioni e Collaborazioni Scrivi a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Nerder Things il primo format di Radio Ugi che affronta il mondo dell'irreale e del surreale per scoprirne gli arcani segreti in salsa nerd! Gli ingredienti? Serie tv, film, fumetti, supereroi e videogames, il tutto con la giusta proporzione di simpatia e divertimento. Una "real nerd" e un "nerd 2.0" sono i nostalgici conduttori di questo programma, che vi stupirà e incuriosirà con argomenti nuovi ed inverosimili. Stay Nerd, stay Ugi! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori Informazioni e Collaborazioni Scrivi a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Ugi nel Pallone è il programma radiofonico che ti permette di vedere lo sport attraverso gli occhi dei ragazzi e dei volontari di Casa Ugi. Commenti, ospiti, notizie e tante risate sono gli ingredienti che cucineremo ogni domenica per voi. Seguici per scoprire le ultime novità dal mondo del calcio e dello sport. Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Su Radio Ugi approda La Classifica! Ma non una classifica qualsiasi... Ogni settimana verrà proposto a bambini e ragazzi un tema diverso, che spazierà dalla musica, ai film, ai supereroi e tanto altro! Loro saranno chiamati a compilare una classifica mettendo al prima posto ciò che più amano e che più li appassiona, diventando giudici nel decretare la medaglia d'oro nella classifica della settimana . È un format pensato proprio per i nostri piccoli bimbi Ugi che avranno modo di commentare dal vivo o lasciare un loro prezioso commento sui questionari della CLASSIFICA!!! Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Ugi nel Pallone è il programma radiofonico che ti permette di vedere lo sport attraverso gli occhi dei ragazzi e dei volontari di Casa Ugi. Commenti, ospiti, notizie e tante risate sono gli ingredienti che cucineremo ogni domenica per voi. Seguici per scoprire le ultime novità dal mondo del calcio e dello sport. Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Ugi nel Pallone è il programma radiofonico che ti permette di vedere lo sport attraverso gli occhi dei ragazzi e dei volontari di Casa Ugi. Commenti, ospiti, notizie e tante risate sono gli ingredienti che cucineremo ogni domenica per voi. Seguici per scoprire le ultime novità dal mondo del calcio e dello sport. Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Ugi nel Pallone è il programma radiofonico che ti permette di vedere lo sport attraverso gli occhi dei ragazzi e dei volontari di Casa Ugi. Commenti, ospiti, notizie e tante risate sono gli ingredienti che cucineremo ogni domenica per voi. Seguici per scoprire le ultime novità dal mondo del calcio e dello sport. Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Ugi nel Pallone è il programma radiofonico che ti permette di vedere lo sport attraverso gli occhi dei ragazzi e dei volontari di Casa Ugi. Commenti, ospiti, notizie e tante risate sono gli ingredienti che cucineremo ogni domenica per voi. Seguici per scoprire le ultime novità dal mondo del calcio e dello sport. Ascolta Radio Ugi su https://share.xdevel.com/player/1589 Per Maggiori informazioni o per proporre collaborazioni scrivete a radiougi@ugitorino.org www.ugi-torino.org
Oggi Leandro viene a raccontare il suo album in uscita su un palco unico: quello di UGI onlus! Special Stage è la prima rassegna musicale di alta qualità per giovani musicisti, cantanti e band che valorizzano il proprio talento all’interno di un progetto sociale. Sono ammessi tutti i generi musicali, dal rock al pop, alla musica classica, jazz, country e tutto ciò che può portare energia positiva su un palco speciale! Le performance si realizzeranno nei reparti di degenza degli ospedali italiani aderenti all'iniziativa (sedi di Milano, Catanzaro, Roma, Torino e Iglesias) con la supervisione e la consulenza di importanti artisti della musica italiana e il supporto dei volontari di Officine Buone.
Ritorna un apprezzatissimo ospite di Ugi, Jeremiah Fraites dei The Lumineers. Oggi la sua generosità si è mostrata a noi tutti, in quanto lui e sua moglie Francesca han deciso di adottare un appartamento della nostra struttura!
Oggi un ospite eccezionale è passato da Radio Ugi: Jeremiah Fraites dei The Lumineers. Abbiamo parlato un po' in italiano, un po' in inglese, molto male ma il divertimento è assicurato! Today a special guest came at Radio Ugi: Jeremiah Fraites from The Lumineers. We spoke a little italian, a little english (both bad) but we enjoyed our mutual company! Radio Ugi è la radio Ufficiale di UGI Onlus (Unione Genitori Italiani contro il tumore dei Bambini), dove sono i bambini stessi a fare la radio! Seguici sui Social e ascoltaci al link: https://share.xdevel.com/player/1589 Radio Ugi is Ugi Onlus's official radio station. Ugi stands for Italian Parents' Union against Child cancer and we're a association that works closely with Regina Margherita Child Hospital in Turin, Italy. In our Radio station the little patience are the speaker: Follow Us on Social Networks and listen to our program here: https://share.xdevel.com/player/1589
Alla scoperta di tutti i segreti del reparto di Oncoematologia Pediatrica del Regina Margherita, le nuove frontiere della medicina, i gruppi e le associazioni che collaborano con Ugi ed il lato umano che sta dietro alla cura, in ogni sua accezione. Direttamente dall'Ospedale Regina Margherita abbiamo avuto occasione di intervistare Marina de Nardo dell'Associazione Bambini Cardiopatici.
Durante la Festa di UGI del 2016 la nostra Fatima esordisce con una serie di punti di vista estremamente interessanti. Estratti dell'emittente Radio UGI, Radio Ufficiale di UGI Onlus (Unione Genitori Italiani contro il Tumore dei Bambini) avente sede in Torino, Italia. Vi invitiamo ad ascoltare la radio al seguente Link: https://share.xdevel.com/player/1589 Per supportarci o per informazioni scrivete a radiougi@ugitorino.org
Il Poeta Alessandro Burbank esalta i giovani ospiti di casa Ugi con una poesia sulle Rose. Estratti dell'emittente Radio UGI, Radio Ufficiale di UGI Onlus (Unione Genitori Italiani contro il Tumore dei Bambini) avente sede in Torino, Italia. Vi invitiamo ad ascoltare la radio al seguente Link: https://share.xdevel.com/player/1589 Per supportarci o per informazioni scrivete a radiougi@ugitorino.org
Il Vicepresidente di UGI rilascia una dichiarazione ai microfoni di Radio UGI durante la festa del 2017 Estratti dell'emittente Radio UGI, Radio Ufficiale di UGI Onlus (Unione Genitori Italiani contro il Tumore dei Bambini) avente sede in Torino, Italia. Vi invitiamo ad ascoltare la radio al seguente Link: https://share.xdevel.com/player/1589 Per supportarci o per informazioni scrivete a radiougi@ugitorino.org
Intervista a Marina Fiorini, referente generale dei volontari di UGI. Estratti dell'emittente Radio UGI, Radio Ufficiale di UGI Onlus (Unione Genitori Italiani contro il Tumore dei Bambini) avente sede in Torino, Italia. Vi invitiamo ad ascoltare la radio al seguente Link: https://share.xdevel.com/player/1589 Per supportarci o per informazioni scrivete a radiougi@ugitorino.org
Intervento alla Festa di Natale di Ugi 2016 dell'Associazione Essere Clown Verona Onlus.
We’re back for another info-packed episode of Keto Talk! In this episode, Jimmy and Dr. Will Cole answer your questions about Overwhelming Carb Cravings On Keto, Deposits Of Cholesterol On Face, Genetic Liver Cirrhosis, Bloating On Keto, Diabetic Neuropathy Treatment, and more! “It’s not the ketogenic diet that failed them, it’s how they prepared for it and what they were eating that was not working for them.” Dr. Will Cole People can so easily psyche themselves into doing keto badly and then blame keto for not working: Tried the Keto Diet, and I Hated Each Second of It Paid advertisement HOT TOPICS: Do people with Celiac disease need to eat more fat due to poor absorption? Does keto lead to an elevated level of bilirubin in the urine? Should I be concerned about my LP PLA2 being elevated (over 200) after starting keto? Why is my fasting insulin so high at 7.3 despite being strict keto without cheating at all? What if any impact does your blood type have on your body’s ability to be in ketosis? Paid advertisement HEALTH HEADLINES: Nutritionists Reveal Why People Listen To Low Carb Gurus Instead Of Science “Keto Diarrhea” Is Just One of the Many Gnarly Truths About the Keto Diet Best way to lose weight fast is to SWITCH between keto and low-carb diets Meatless meat is having a moment. Will eggless eggs be next? Low carb diet leads to “clinical remission” in three case studies of adults with type 1 diabetes STUDY: Train your brain with computer game to eat less sugar “I think the best ketogenic approach in the world will become unraveled if you aren’t sleeping and are stressed.” Jimmy Moore Your Questions: What can I do to help get rid of the persistent and overwhelming carb cravings that hit me even while eating keto? Hey Jimmy and Will, I recently joined in on Jimmy’s 7-day fasting challenge on Instagram and they were so incredibly helpful. I was really hoping that would be a reset for me and a springboard into eating clean keto. I’ve been struggling for years with on again off again low-carb eating, but I just have super intense carb cravings. I ended up going through my time of the month and struggling through that last day of the fast and then crashed and burned back into eating tons of carbage afterwards. I caught your emotional eating JIMMY RANTS episode and I just need some help with figuring out how to conquer the craving insanity that I just can’t always willpower through. I want to be successful once and for all, but I’m feeling like a failure here, yo-yoing at very high weights, with Type 2 diabetes. I know that the answer to this lies within eating a keto template and I’m not afraid to put in the hard work to make it happen. But I definitely feel controlled by food. I refuse to believe that I have to have a dangerous weight loss surgery to conquer this problem, but I’ve been winning some battles but losing the war for years. What do you recommend for the obsessive, overwhelming cravings, and persistent thoughts about food? How do I get actual control over this? Thanks so much, Rhonda If cholesterol isn’t a bad thing, then why did keto lead to these permanent deposits of cholesterol underneath my eyelids? Hey Jimmy and Dr. Cole, Thanks for this podcast. I started reading Jimmy’s book Cholesterol Clarity recently because I developed these yellow bumpy lines under my eyes and was told it’s because I have high cholesterol. I went to the doctor and immediately they wanted to put me on statins. I hate going to the because of this kinda thing. They didn’t even go over the results with me. They had the front desk call me and tell me I had a high cholesterol number and that there was a prescription for statins waiting for me at the pharmacy. I didn’t take them, of course, and I retested after a three-month, 30l-pound keto weight loss and it was even higher. The doctor again insisted I take a statin and I again refused. My question for you guys is if cholesterol isn’t bad, then why do these permanent deposits of cholesterol end up on my face? They look horrible and I’m told they will never go away on their own. How and why does this happen? I wanted to show you these yellow things on my face and I wondered if you had any knowledge about them. Thank you for answering my question. Louise Would a genetic liver cirrhosis condition be hindered or helped by eating a low-carb, high-fat, ketogenic diet? Greetings Jimmy and Will, My boyfriend was recently diagnosed with liver cirrhosis which developed as en effect of a genetic disorder he was not aware of. He’s never been much a drinker and he definitely doesn’t drink now. He works out regularly and eats somewhat “healthy” according to his doctors. He’s in great shape especially for someone with only 20% liver function. I read somewhere that a hepatic diet is made up of primarily carbs since protein breakdown is impaired and fat is bad for the liver. I by no means consider myself an expert on nutrition and metabolism, but this sounds like total BS to me. It doesn’t make sense to feed your liver carbs which turn into sugar. In my mind, it just makes sense that a keto diet is the way to go in conjunction with coffee enemas perhaps. What do you think? I want to learn and do as much as I can to help my boyfriend have the best life and the best health possible. Thank you, Brenda Why do I have bloating when I eat keto foods? Why won’t my Ketonix breath ketone analyzer show the presence of ketosis with anything I do? Hi Jimmy and Dr. Cole, I love your show and never miss an episode because it really helps keep me on track. I’m a 31-year old breastfeeding female and have been eating keto since January 2017. When I transitioned to keto, I had already been breastfeeding my daughter for 10 months and I was starting to struggle with weight gain and hunger that was much worse than when I was pregnant. I ate whole organic foods and took probiotics for years but still consumed far too much sugar (honey, coconut sugar, and grains) and I knew I had to make a change when I started gaining more weight than I ever had in my life and having an insatiable appetite for sugar. My transition was rough and I had keto flu and lightheadedness for weeks despite consuming plenty of water, salt loading, and taking a multimineral supplement. Urine test strips at the time showed that my ketones were off the charts high. At the beginning of my pregnancy my hemoglobin A1C was prediabetic, but after a few months on keto it was down to normal. My fasting blood sugar in the morning is now 83, and it drops to 76 after my 25 minute beginner’s strength training workout and 59 two hours after my usual breakfast of scrambled eggs. In the evening, 2 hours after dinner, it is around 80. I lost about 30 pounds in the first months and my milk supply never dropped (I’m still breastfeeding now, almost a year on keto later, with no problems.) I love the ketogenic way of eating and am so thankful to be off carbs, but I have two main concerns: the first one is constant bloating. When I still ate carbs I had stomach pain every morning that improved after eating breakfast. Now that I’m keto I tend to feel very bloated after meals. I eat dairy and nuts, but temporarily cutting them out of my diet and it doesn’t seem to make a difference. Sometimes my worst bloating is after eating something like riced cauliflower with bacon. It seems like everything sits in my stomach too long. And I really can’t handle seltzer water! I once had a UGI endoscopy in my stomach for the stomach pain years ago and it showed everything normal except for low stomach acid. Could that be the problem? How do I increase stomach acid? I also sometimes have nausea and an acid taste, like reflux symptoms, although I’ve never had heartburn. My other concern is with testing my ketones. I use the Ketonix breath analyzer and no matter what I do, I blow green. If I have a glass of dry champagne the night before and keto treats full of almond flour and cheese, I blow green the next day. If I intermittent fast for three days and eat very strict keto, I still blow green! How is this possible? Am I truly in ketosis? Thank you so much for your help! Rachel KETO TALK MAILBOX: Paid advertisement Would the inevitable diabetic neuropathy be rectified more effectively with IF and keto than with Gabapentin? Hey guys, My boyfriend’s mother was just diagnosed with Type 2 diabetes. Unfortunately, she suffers from horrible neuropathy and finds it very difficult to sleep at night which is very common. I have read on the Internet that people with neuropathy most of the time are prescribed a drug called Gabapentin. To my surprise, they are also prescribes to patients as antidepressants. The more I think about it, long-term use of these drugs has to be very difficult on the kidneys and liver which is a double whammy for diabetics who already have issues with both of these organs. To me, it seems intermittent fasting and keto can help solve this neuropathy without the need for any risky medications. In your functional medicine practice, Dr. Cole, have you found this to be true in your patients? Sincerely, Emi
Gastritis/Peptic Ulcer Disease Etiology #1 H. Pylori Infection #2 NSAIDs Consider Zollinger-Ellison Syndrome or Cancer in non-healing gastric ulcers Discussed Below Symptoms Gastritis alone, typically asymptomatic Dyspepsia (epigastric pain) GI Bleed PUD #1 cause of UGI bleed Located in stomach or duodenum Duodenum most common Pain worse before meals or 2-5 hr after meals Pain … Continue reading Disorders of the Stomach →
Spinning® studio owner Suzanne Olson, along with her 4 partners, runs Pure Energy in Paoli, PA . Suzanne joins me to discuss how she ensures a quality experience for her participants, in their multi-format fitness studio. Pure Energy's Facebook page. https://www.buzzsprout.com/161023/687753-ici-podcast-321-meet-spinning-studio-owner-suzanne-olson-from-pure-energy.mp3 Studio Specifications: Opened April 1st 2014 Formats offered: Spinning, Yoga, Barre, Aerial Yoga, Pilates, Zumba, Boxing and Ugi + wellness programs. 6,000 sq ft, broken into 5 studios Website designed Continue Reading... The post ICI Podcast 321 – Meet Spinning® studio owner Suzanne Olson from Pure Energy appeared first on Indoor Cycle Instructor Podcast | ICI/PRO Premium Education.
Thea Phalon, Community Relations Manager for UGI, joins Dan to talk about the impact of BIG Vision on the community and why they feel it is a perfect partnership between BIG Vision and UGI!
Thea Phalon, Community Relations Manager for UGI, joins Dan to talk about the impact of BIG Vision on the community and why they feel it is a perfect partnership between BIG Vision and UGI!
Abdominal pain is common; so are strongly held myths and legends about what is concerning, and what is not. One of our largest responsibilities in the Emergency Department is sorting out benign from surgical or medical causes of abdominal pain. Morbidity and mortality varies by age and condition. Abdominal Surgical Emergencies in Children: A Relative Timeline General Advice Neonate (birth to one month) Necrotizing Enterocolitis Pneumatosis Intestinalis. Essentials: Typically presents in 1st week of life (case reports to 6 months in chronically ill children) Extend suspicion longer in NICU graduates Up to 10% of all cases of necrotizing enterocolitis are in full-term children Pathophysiology is unknown, but likely a translocation of bacteria Diagnosis: Feeding intolerance, abdominal distention Abdominal XR: pneumatosis intestinalis Management: IV access, NG tube, broad-spectrum antibiotics, surgery consult, ICU admission Intestinal Malrotation with Volvulus Essentials: Corkscrew Sign in Malrotation with Volvulus Bilious vomiting (80-100%) in the 1st month; especially in the 1st week May look well initially, then rapidly present in shock Ladd’s bands: abnormally high tethering of cecum to abdominal wall; peristalsis, volvulus, ischemia Diagnosis: History of bilious emesis is sufficient to involve surgeons Upper GI series: corkscrew appearance US (if ordered) may show abnormal orientation of and/or flow to superior mesenteric artery and vein Management: Stat surgical consult IV access, resuscitation, NG tube to decompress (bowel wall perfusion at risk, distention worsens) Hirschprung Disease Essentials: Problem in migration of neural crest cells Aganglionic colon (80% rectosigmoid; 15-20% proximal to sigmoid; 5% total colonic aganglionosis) colon (known as short-segment disease) Poor to no peristalsis: constipation, perforation, and/or sepsis Diagnosis: May be diagnosed early as “failure to pass meconium in 1st 48 hours” In ED, presents as either bowel obstruction or enterocolitis Contrast enema Beware of the toxic megacolon (vomiting, distention, sepsis) Management: Resuscitation, antibiotics, NG tube decompression, surgical consultation; stable patients may need rectal biopsy for confirmation Staged surgery (abdominoperineal pull-through with diverting colostomy, subsequent anastomosis) versus one-stage repair. Infant and Toddler (1 month to 2 years) Pyloric Stenosis Essentials: Hypertrophy of pyloric sphincter; genetic, environmental, exposure factorsString Sign in Pyloric Stenosis. Diagnosis: Hungry, hungry, not-so-hippos; they want to eat all of the time, but cannot keep things down Poor weight gain (less than 20-30 g/day) US: “π–loric stenosis” (3.14); pylorus dimensions > 3 mm x 14 mm UGI: “string sign” Management: Trial of medical treatment with oral atropine via NGT (muscarinic effects decrease pyloric tone) Ramstedt pyloromyotomy (definitive) Intussusception Essentials: Majority (90%) ileocolic; no pathological lead point Small minority (4%) ileoileocolic due to lead point: Meckel’s diverticulum, polyp, Peyer’s patches, Henoch-Schönlein purpura (intestinal hematoma) Diagnosis: Target Sign (Donut Sign). Ultrasound sensitivity and specificity near 100% in experienced hands Abdominal XR may show non-specific signs; used mainly to screen for perforation before reduction Management: Hydrostatic enema: contrast (barium or water-soluble contrast with fluoroscopy) or saline (with ultrasound) Air-contrast enema: air or carbon dioxide (with either fluoroscopy or ultrasound); higher risk for perforation than hydrostatic (1% risk), but generally safer than perforation from contrast Consider involving surgical service early (precaution before reduction) Traditional disposition is admission; controversial: home discharge from ED Young Child and Older (2 years and up) Appendicitis Essentials: Appendicitis occurs in all ages, but rarer in infants. Infants do not have fecalith; rather they have some other anatomic or congenital condition. More common in school-aged children (5-12 years) and adolescents Younger children present atypically, more likely to have perforated when diagnosed. Diagnosis: Non-specific signs and symptoms Often have abdominal pain first; vomiting comes later Location/orientation of appendix varies Appendicitis scores vary in their performance Respect fever and abdominal pain Management: Traditional: surgical On the horizon: identification of low-risk children who may benefit from trial of antibiotics If perforated, interval appendectomy (IV antibiotics via PICC for 4-6 weeks, then surgery) Obstruction SBO. Incarcerated Inguinal Hernia. Essentials: Same pathophysiology and epidemiology as adults: “ABC” – adhesions, “bulges” (hernias), and cancer. Diagnosis: Obstruction is a sign of another condition. Look for cause of obstruction: surgical versus medical Abdominal XR in low pre-test probability CT abdomen/pelvis for moderate-to-high risk; confirmation and/or surgical planning Management: Treat underlying cause NG tube to low intermittent wall suction Admission, fluid management, serial examinations Take these pearls home: Consider surgical pathology early in encounter Resuscitate while you investigate Have a low threshold for imaging and/or consultation, especially in preverbal children Selected References Necrotizing Enterocolitis Neu J, Walker A. Necrotizing Enterocolitis. N Eng J Med. 2011; 364(3):255-264. Niño DF et al. Necrotizing enterocolitis: new insights into pathogenesis and mechanisms. Nature. 2016; 13:590-600. Walsh MC et al. Necrotizing Enterocolitis: A Practitioner’s Perspective. Pediatr Rev. 1988; 9(7):219-226. Malrotation with Midgut Volvulus Applegate KE. Intestinal Malrotation in Children: A Problem-Solving Approach to the Upper Gastrointestinal Series. Radiographics. 2006; 26:1485-1500. Kapfer SA, Rappold JF. Intestinal Malrotation – Not Just the Pediatric Surgeon’s Problem. J Am Coll Surg. 2004; 199(4):628-635. Lee HC et al. Intestinal Malrotation and Catastrophic Volvulus in Infancy. J Emerg Med. 2012; 43(1):49-51. Martin V, Shaw-Smith C. Review of genetic factors in intestinal malrotation. Pediatr Surg Int. 2010; 26:769-781. Nehra D, Goldstein AM. Intestinal malrotation: Varied clinical presentation from infancy through adulthood. Surgery. 2010; 149(3):386-391. Hirschprung Disease Amiel J, Sproat-Emison E, Garcia-Barcelo M, et al. Hirschsprung disease, associated syndromes and genetics: a review. J Med Genet 2008; 45:1. Arshad A, Powell C, Tighe MP. Hirschsprung's disease. BMJ 2012; 345:e5521. Aworanti OM, McDowell DT, Martin IM, Quinn F. Does Functional Outcome Improve with Time Postsurgery for Hirschsprung Disease? Eur J Pediatr Surg 2016; 26:192. Clark DA. Times of first void and first stool in 500 newborns. Pediatrics 1977; 60:457. Dasgupta R, Langer JC. Evaluation and management of persistent problems after surgery for Hirschsprung disease in a child. J Pediatr Gastroenterol Nutr 2008; 46:13. De Lorijn F, Reitsma JB, Voskuijl WP, et al. Diagnosis of Hirschsprung's disease: a prospective, comparative accuracy study of common tests. J Pediatr 2005; 146:787. Doig CM. Hirschsprung's disease and mimicking conditions. Dig Dis 1994; 12:106. Khan AR, Vujanic GM, Huddart S. The constipated child: how likely is Hirschsprung's disease? Pediatr Surg Int 2003; 19:439. Singh SJ, Croaker GD, Manglick P, et al. Hirschsprung's disease: the Australian Paediatric Surveillance Unit's experience. Pediatr Surg Int 2003; 19:247. Suita S, Taguchi T, Ieiri S, Nakatsuji T. Hirschsprung's disease in Japan: analysis of 3852 patients based on a nationwide survey in 30 years. J Pediatr Surg 2005; 40:197. Sulkowski JP, Cooper JN, Congeni A, et al. Single-stage versus multi-stage pull-through for Hirschsprung's disease: practice trends and outcomes in infants. J Pediatr Surg 2014; 49:1619. Pyloric Stenosis Aspelund G, Langer JC. Current management of hypertrophic pyloric stenosis. Semin Pedaitr Surg. 2007; 16:27-33. Dias SC et al. Hypertrophic pyloric stenosis: tips and tricks for ultrasound diagnosis. Insights Imaging. 2012; 3:247-250. Kawahara H et al. Medical treatment of infantile hypertrophic pyloric stenosis: should we always slice the olive? J Pediatr Surg. 2005; 40:1848-1851. Mack HC. Adult Hypertrophic Pyloric Stenosis. Arch Inter Med. 1959; 104:78-83. Meissner PE et al. Conservative treatment of infantile hypertrophic pyloric stenosis with intravenous atropine sulfate does not replace pyloromyotomy. Pediatr Surg Int. 2006; 22:1021-1024. Mercer AE, Phillips R. Can a conservative approach to the treatment of hypertrophic pyloric stenosis with atropine be considered a real alternative to pyloromyotomy? Arch Dis Child. 2013; 95(6): 474-477. Pandya S, Heiss K, Pyloric Stenosis in Pediatric Surgery.Surg Clin N Am. 2012; 92:527-39. Peters B et al. Advances in infantile hypertrophic pyloric stenosis. Expert Rev Gastroenterol Hepatol. 2014; 8(5):533-541. Intussusception Apelt N et al. Laparoscopic treatment of intussusception in children: A systematic review. J Pediatr Surg. 2013; 48:1789-1793. Applegate KE. Intussusception in Children: Imaging Choices. Semin Roentgenol. 2008; 15-21. Bartocci M et al. Intussusception in childhood: role of sonography on diagnosis and treatment. J Ultrasound. 2015; 18 Gilmore AW et al. Management of childhood intussusception after reductiion by enema. Am J Emerg Med. 2011; 29:1136-1140.:205-211. Chien M et al. Management of the child after enema-reduced intussusception: hospital or home? J Emerg Med. 2013; 44(1):53-57. Cochran AA et al. Intussusception in traditional pediatric, nontraditional pediatric, and adult patients. Am J Emerg Med. 2011; 523-527. Loukas M et al. Intussusception: An Anatomical Perspective With Review of the Literature. Clin Anatomy. 2011; 24: 552-561. Mendez D et al. The diagnostic accuracy of an abdominal radiograph with signs and symptoms of intussusception. Am J Emerg Med. 2012; 30:426-431. Whitehouse et al. Is it safe to discharge intussusception patients after successful hydrostatic reduction? J Pediatr Surg. 2010; 45:1182-1186. Appendicitis Amin P, Chang D. Management of Complicated Appendicitis in the Pediatrc Population: When Surgery Doesn’t Cut it. Semin Intervent Radiol. 2012; 29:231-236 Blakely ML et al. Early vs Interval Appendectomy for Children With Perforated Appendicitis. Arch Surg. 2011; 146(6):660-665. Bundy DG et al. Does This Child Have Appendicitis? JAMA. 2007; 298(4):438-451. Cohen B et al. The non-diagnostic ultrasound in appendicitis: is a non-visualized appendix the same as a negative study? J Pediatr Surg. 2015 Jun;50(6):923-7 Herliczek TW et al. Utility of MRI After Inconclusive Ultrasound in Pediatric Patients with Suspected Appendicitis. AJT. 2013; 200:969-973. Janitz et al. Ultrasound Evaluation for Appendicitis. J Am Osteopath Coll Radiol. 2016; 5(1):5-12. Kanona H et al. Stump Appendicitis: A Review. Int J Surg. 2012; 10:4255-428. Kao LS et al. Antibiotics vs Appendectomy for Uncomplicated Acute Appendicitis. Evid Based Rev Surg. 2013;216(3):501-505. Petroianu A. Diagnosis of acute appendicitis. Int J Surg. 2012; 10:115-119. Mazeh H et al. Tip appendicitis: clinical implications and management. Amer J Surg. 2009; 197:211-215. Puig S et al. Imaging of Appendicitis in Children and Adolescents. Semin Roentgenol. 2008; 22-28. Schizas AMP, Williams AB. Management of complex appendicitis. Surgery. 2010; 28(11):544-548. Shogilev DJ et al. Diagnosing Appendicitis: Evidence-Based Review. West J Emerg Med. 2014; 15(4):859-871. Wray CJ et al. Acute Appendicitis: Controversies in Diagnosis and Management. Current Problems in Surgery. 2013; 50:54-86 Intestinal Obstruction Babl FE et al. Does nebulized lidocaine reduce the pain and distress of nasogastric tube insertion in young children? A randomized, double-blind, placebo-controlled trial. Pediatrics. 2009 Jun;123(6):1548-55 Chinn WM, Zavala DC, Ambre J. Plasma levels of lidocaine following nebulized aerosol administration. Chest 1977;71(3):346-8. Cullen L et al. Nebulized lidocaine decreases the discomfort of nasogastric tube insertion: a randomized, double-blind trial. Ann Emerg Med. 2004 Aug;44(2):131-7. Gangopadhyay AN, Wardhan H. Intestinal obstruction in children in India. Pediatr Surg Int. 1989; 4:84-87. Hajivassiliou CA. Intestinal Obstruction in Neonatal/Pediatric Surgery. Semin Pediatr Surg. 2003; 12(4):241-253. Hazra NK et al. Acute Intestinal Obstruction in children: Experience in a Tertiary Care Hospital. Am J Pub Health Res. 2015; 3(5):53-56. Kuo YW et al. Reducing the pain of nasogastric tube intubation with nebulized and atomized lidocaine: a systematic review and meta-analysis. J Pain Symptom Manage. 2010 Oct;40(4):613-20. . Pediatric Surgery Irish MS et al. The Approach to Common Abdominal Diagnoses in Infants and Children. Pedaitr Clin N Am. 1998; 45(4):729-770. Louie JP. Essential Diagnosis of Abdominal Emergencies in the First Year of Life. Emerg Med Clin N Am. 2007; 25:1009-1040. McCullough M, Sharieff GQ. Abdominal surgical emergencies in infants and young children. Emerg Med Clin N Am. 2003; 21:909-935. Pepper VK et al. Diagnosis and Management of Pediatric Appendicitis, Intussusception, and Meckel Diverticulum. Surg Clin N Am. 2012 This post and podcast are dedicated to Mr Ross Fisher for his passion and spirit of collaboration in all things #FOAMed. Thank you, sir!
Dave Lindenmuth, Director of Marketing UGI Energy Services, talks about the Reading Royals Suite experiences he is able to offer to others in the community. UGI Energy Services has a suite in Santander Arena at Center Ice and he says it’s great place to entertain clients, it’s all about the experience.UGI Energy Services relationship started with the Royals by placing a banner at the rink, then they invested in a half suite. Dave says, “The experience we were able to share with our clients was so successful we now have a full suite. We are able to entertain lots of customers and treat employees and guests. “The feedback we get is tremendous”. Dave attribute the success to the collaborative efforts of the Reading Royals. UGI community initiatives are in line with the Reading Royals. On Veterans Game Day we donate our suite to veteran retirees and their families and on Martin Luther King Day we treat Mentors For Berks Youth. We are able to donate our suite tickets to the scouts for Boy Scouts Games. The personalized opportunities we are able to provide are available because of the Royals commitment have to partnering with so many organizations in this community.
Kelly Beaver, Ruth Hartman's Granddaughter, talks with Dan Clouser about breaking down barriers for women. Kelly is a Vice President at UGI and says it is important for women not to play into stereotypes and be a victim. Kelly shares some of the lessons she learned from the great Ruth Hartman!
Kelly Beaver, Ruth Hartman's Granddaughter, talks with Dan Clouser about breaking down barriers for women. Kelly is a Vice President at UGI and says it is important for women not to play into stereotypes and be a victim. Kelly shares some of the lessons she learned from the great Ruth Hartman!
If you've ever had an idea for a new, fitness related product or service? Dream about building a company around your new widget and then selling your company to a larger company? If that sounds like you, you'll want to listen to this interview with fitness entrepreneur Sara Shears. Sara invented the Ugi ball to help her personal training clients train more frequently. After years of effort, she was Continue Reading... The post ICI Podcast 319 – Developing your fitness product or service idea and then selling it to a large fitness brand appeared first on Indoor Cycle Instructor Podcast | ICI/PRO Premium Education.
A wonderful story was recently written by Robert England about a company that has experienced an amazing turn-around. The company is United Guaranty Insurance (UGI). On today's broadcast, we will have Robert on the program to discuss how UGI has made an amazing comeback and what he learned while researching this inspiring story. A wonderful story was recently written by Robert England about a company that has experienced an amazing turn-around. The company is United Guaranty Insurance (UGI). On today's broadcast, we will have Robert on the program to discuss how UGI has made an amazing comeback and what he learned while researching this inspiring story.
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