English cricketer and umpire
POPULARITY
Hosted by Mark Benson
3 episodes with Mark Benson
2 episodes with Mark Benson
4 episodes with Mark Benson
2 episodes with Mark Benson
2 episodes with Mark Benson
3 episodes with Mark Benson
2 episodes with Mark Benson
4 episodes with Mark Benson
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Mark Benson, MD Colonic perforations during colonoscopy are rare, but when they occur, taking swift and informed action is critical, particularly to avoid surgical intervention. Joining Dr. Peter Buch to offer his insights on perforation prevention, risk-reduction techniques, and repair strategies is Dr. Mark Benson, an advanced endoscopist and Associate Professor in the Division of Gastroenterology and Hepatology at the University of Wisconsin School of Medicine.
Saunders International Ltd Managing Director and CEO Mark Benson talked with Proactive at the AIM's Small and Midcap Conference about the company's strong momentum, recent project wins and the strategic expansion into defense and infrastructure sectors. Benson highlighted Saunders' transformation from a tank constructor to a multi-disciplined, end-to-end engineering and construction provider. “We've diversified and become a multi-disciplined business… Now some of the projects we can do end-to-end,” he said, referencing the company's work on the **Western Sydney Airport**, where it completed all elements from fuel tank construction to apron pipeline delivery. He also noted Saunders' acquisition strategy as a driver of growth, enabling delivery of complex infrastructure through internal capabilities. Notable acquisitions include piping, civil infrastructure, and automation companies, helping the company expand its offering and grow organically and through M&A. Benson discussed the company's extensive work in the defense sector, including the **Larrakeyah Defense Precinct** in Darwin, where Saunders handled the complete marine diesel infrastructure — from delivery to ship fueling — a capability he said sets the company apart. “Typically it's done through 3 to 6 contractors. Now we can do that end to end.” The company now sees a $2.3 billion pipeline of directly addressable opportunities, with up to $4.8 billion in total defense-related fuel infrastructure upgrades anticipated across the next decade. Saunders is actively tendering for $580 million of that. Benson said Saunders' unique value in defense projects includes not just technical delivery but risk reduction for government clients. “In defense, it's not all about price. Sometimes price evaluation is only 30%. It's about de-risking the project for the Commonwealth.” Visit Proactive's YouTube channel for more company interviews, and don't forget to like the video, subscribe to the channel, and turn on notifications to stay updated. #SaundersInternational #ASXStocks #InfrastructureDevelopment #DefenseContracts #WesternSydneyAirport #Larrakeyah #EngineeringProjects #FuelInfrastructure #MarkBenson #ASXConference #ProactiveInvestors #ConstructionNews #ProjectPipeline
Text us for a shout out! Customer service is a common thread running through all of the Impact Service Groups new HVAC Remote Equipment Monitoring system called Nebula. The patent pending product connects remotely to HVAC units monitoring them for a variety of performance factors with the common goal of keeping the HVAC equipment operating efficiently.Impact Service Group's owner and COO, Mark Benson, is our special guest as he explains how hundreds of Impact Service Group's highly skilled and trained Service Technicians coupled with the advanced technology of Nebula's Remote Equipment Monitoring acts as a force multiplier for Facility Managers who are tasked with keeping HVAC systems operating to keep businesses open and operating. Support the showThe Florida Business Forum Podcast is now Florida's Number One Business Forum Podcast based on an independent survey of more than 400 Florida businesses and not-for-profit organizations. Produced by Yates & Associates, Public Relations & Marketing, and hosted by Emmy Award winning reporter and television anchor Sam Yates, The Florida Business Forum Podcast is your source for detailed Florida business and not-for-profit news. If you or your business or not-for-profit organization would like to share your news with our Florida, national, and international audience please contact Sam Yates, Sam@YatesPRO.com. The Florida Business Forum Podcast is the only business forum of its kind dedicated to Florida news, business, and not-for-profit organizations. When Florida business minds need to know, they turn to The Florida Business Forum Podcast first!Program Sponsorships are available starting at $500/monthly with a minimum six-month sponsorship. The Florida Business Forum Podcast is affiliated with the Pod National News Network USA providing business news podcasts to every State in the U.S.A. The Florida Business Forum Podcast is heard throughout Florida, the United States, and 32 countries and territories. Direct Media Inquiries to Sam Yates, Sam@Yatespro.com. Or via text to 7725285185.
On The Speed of Culture Podcast, Mark Benson, Head of Samsung SmartThings US, breaks down the next wave of AI-driven smart home innovation. From seamless device interoperability to AI-powered automation and SmartThings Pro's expansion into enterprise, Mark shares how Samsung is transforming the way people interact with their homes, cars, and workplaces.Follow Suzy on Twitter: @AskSuzyBizFollow Mark Benson on LinkedInSubscribe to The Speed of Culture on your favorite podcast platform.And if you have a question or suggestions for the show, send us an email at suzy@suzy.com Hosted on Acast. See acast.com/privacy for more information.
Check out this message from Pastor Mark Benson at Dothan First.
Check out this message from Pastor Mark Benson at Dothan First.
Check out this message from Pastor Mark Benson at Dothan First.
In this episode of Mutuality Matters, hosts Tara and Todd Korpi welcome Pastors Mark and Michelle Benson, co-lead pastors from Dothan Assembly in Alabama. Mark and Michelle share their journey of co-pastoring, highlighting the biblical call for gender equality in leadership. They discuss the challenges and growth experienced in their ministry, the importance of recognizing each other's strengths, and navigating environments resistant to female leadership. The episode emphasizes the significance of knowing one's calling, maintaining humility, and fostering strong, supportive relationships in ministry. Listeners also gain insights on how co-leadership can positively influence church culture and leadership practices. 00:00 Introduction to Mutuality Matters 00:24 Hosts' Banter and Jingle Discussion 01:36 Introducing Special Guests: Mark and Michelle Benson 03:37 Journey to Co-Pastoring 08:58 Challenges and Triumphs in Ministry 13:17 Navigating Co-Leadership 31:33 Encouragement for Listeners 33:50 Conclusion and Resources Bios Pastors Mark and Michele have been lead pastors of Dothan First Assembly of God since 2016 after serving at The Rock Family Worship Center based out of Huntsville, Alabama for over ten years. Their passion is to make a difference in the lives of others by showing them the love of Jesus Christ. Pastors Mark and Michele have three children; Taylor, Griffin, and Camryn. Related Resources Women and Men Leading Together: Co-Pastoring While Married Women and Men Leading Together: “Exchanging a Muzzle for a Microphone” with Rici and Phil Skei How to Find a Church that Empowers Women Disclaimer: The opinions expressed in CBE's Mutuality Matters' podcast are those of its hosts or guests and do not purport to reflect the opinions or views of CBE International or its members or chapters worldwide. The designations employed in this podcast and the presentation of content therein do not imply the expression of any opinion whatsoever on the part of CBE concerning the legal status of any country, area or territory or of its authorities, or concerning the delimitation of its frontiers.
Mark Benson from The Control Option joins the show
Integrity, courage, commitment – veterans of the U.S. armed forces possess unique values and skillsets that lift up the dairy industry. This Veteran's Day, we talk with two veterans who have successfully transitioned from active duty to leadership roles within the dairy industry.How can veterans translate their military experience into marketable skills that companies look for when hiring? What difficulties do many veterans face when transitioning to civilian work? Air Force veteran Walter McClung, now the maintenance and facilities manager at Hilmar Cheese, shares how his military background has helped him manage employees and gives his insight into what other veterans can contribute to the industry. Next, we hear from Mark Benson, chief procurement officer and vice president of government affairs and global responsibility at Leprino Foods. Before working in the dairy industry, Mark served in the U.S. Marine Corps, where he managed leadership development trainings and was responsible for procurement and distribution for his battalion. Mark shares with us how he shifted from the service to corporate America, and what lessons he has brought with him from his time in the Marine Corps.The episode is sponsored by Infor. "Infor provides dairy-specific cloud software that addresses catch weight, formula management, regulatory compliance, and delivery forecasting with full supply chain traceability. Find out how at infor.com/dairy"If your company is interested in sponsoring a block of episodes of The Dairy Download, contact IDFA's Melissa Lembke at mlembke@idfa.org.Like the show? Rate The Dairy Download on Apple Podcasts!
Neil is talking about Mike Ranieri's return to brokered radio on WJNA, and TMJ. Henry Barrow called on Neil's 23 anniversary show and explained how the show continued on WAXY after Ranieri left. Mark Benson calls in to talk about his backing of the WAXY show. Mark was part of the anti Cuban movement back in the 1980's. Paul Harvey calls. Jorge last 20 minutes.
Kenya welcomes the multi-talented New York artist, Mark Benson, a filmmaker, actor, and enthusiastic NYC walker. Mark shares his experiences on popular sets like “Law and Order”, “Succession”, and “Billions”, offering insights on finding his place in the entertainment industry and the importance of following your purpose by first loving your soul. He and Kenya discuss the value of creative expression, the beauty of people from diverse backgrounds coming together, and how nice it is when people share their resources to help others network and find their footing in the community. From background acting adventures to making his first short film while working at Krispy Kreme, Mark's journey is filled with inspiration. He also shares a few valuable lessons on dealing with naysayers and staying true to your unique creative path. Also Talked About: If you really want to get to know NYC and connect with amazing people, background acting is a great way to do it. Mark did theater in Philadelphia in the 90s, and from then on he was hooked on performing and creative endeavors. Mark got curious about bigger sets after directing a few short films and decided to sign up for Central Casting. What true diversity looks like in a scene with 600 people, and the beauty of people from all walks of life coming together. When people share resources and aren't territorial with their opportunities or contacts, it is a beautiful thing. How entertainment has mirrored the growth and evolution of the human consciousness… sometimes. More about Mark making his first short film, ‘Casual Friday' while working his corporate job at Krispy Kreme, and the ways that art imitates life. “Love the Soul” is not only the name of Mark's e-mail newsletter and production company but the idea that being in touch with your soul is like pointing your compass in the right direction. It's okay if some people don't get what you're creating. In fact, that means you are doing things right. Say Hi To Us: Needed On Set | FB | IG | TikTok Source & Cast Kenya: IG Guest: Mark: Website | IG
Kyle Gatlin talks with DothanFirst Pastor Mark Benson about Pray Dothan.
"Best Beatles Tribute on Earth" Rolling Stone
Wealth Without Bay Street 152: Coaching Infinite Bankers is what Mark Benson does. An Authorized Infinite Banking Practitioner with the Nelson Nash Institute, Mark Benson discusses the philosophy for achieving victory and happiness. A former coach, he used his experiences in formulating and focusing on strategies that proved successful in financial education.
With SEFCU Arena now 30 years old, the University at Albany has announced major renovation plans for the building that is home to the men's and women's basketball teams. Construction on the project begins in August and is scheduled to be completed in November 2023. The SUNY campus says the $12 million project will be paid for entirely with private funds, with $8.5 million already pledged. UAlbany also announced a separate $2.5 million plan to upgrade the adjacent Physical Education Gym. We speak with UAlbany athletics director Mark Benson.
Mark Benson, AMA Senior Marketing Director, joins the show to talk about club newsletters and how a good communications plan is essential for a healthy club experience!Learn more about the AMA
Entrevista di Dia pa awe 06/06/2022 tabata cu director di Infinity Media sr. Mark Benson-Denz tocante e di 5 E Aruba Seminar 2022
This week LG Debuts a new 4K UST Laser Projector and we discuss five mistakes everyone makes with Sonos Soundbars. Finally, Samsung begins integrating it's SmartThings home automation platform with Matter capable devices. We also read your emails and the week's news. News: Hey Sonos! Company Debuts Entry-Level Soundbar, Voice Control For Music, And New Roam Colors Google TV app to add casting as Android TV ecosystem grows to 110M monthly active device Disney+ beats estimates with 7.9M new subscribers in Q1 Samsung SmartThings begins testing Matter devices on its platform Roku and Element partner for their first outdoor TV LG Debuts New 4K UST Laser Projector LG Electronics is expanding its premium CineBeam 4K laser projector lineup with the new Ultra Short Throw (UST) laser projector (model HU915QE), the follow up to the HU715Q released earlier this year. LG's latest flagship home cinema solution can produce sharp 90-inch images when placed 2.2 inches (5.6 centimeters) from the wall, or 120 inches at a distance of 7.2 inches (18.3 centimeters). The HU915QE plays movies and streaming content in 4K HDR, using HDR Dynamic Tone Mapping to analyze and adjust image brightness every single frame. With LG's webOS smart platform onboard, the HU915QE lets users watch all their favorite shows from streaming services such as Netflix, Amazon Prime Video, Disney+, YouTube, and Apple TV without an additional device. They can also wirelessly stream content via Screen Mirroring, Apple AirPlay2, and Bluetooth. On top of that, its built-in 2.2 Channel, 40-watt speaker system enhances the viewing experience with strong, rich audio. Users can also connect up to two LG Bluetooth speakers at once. LG CineBeam 4K laser projector (model HU915QE) with the latest UST technology will be available in the first half of 2022. No pricing available but Value Electronics is advertising it for $6000 to $6500.. 5 mistakes everyone makes with Sonos soundbars Got a Sonos Beam or Arc? Don't make these classic mistakes Full article here… Mistake 1: ignoring Trueplay room calibration Mistake 2: leaving the TV's sound output in PCM Mistake 3: not trying the speech enhancement feature Mistake 4: not playing with the 'Loudness' feature Mistake 5: missing the new height adjustment feature HOW SAMSUNG'S SMARTTHINGS IS THINKING ABOUT MATTER AND THE FUTURE OF THE SMART HOME The smart home is about to change. Soon, you won't have to choose a smart light bulb or door lock just because it works with your smart speaker. Instead, you'll be able to buy a smart device, bring it home, and it will work with any voice assistant or app you choose. At least, that's the promise behind Matter, a new standard created by Samsung, Google, Apple, and Amazon. Most importantly, you won't be locked into the platform you chose. If you decide you want to switch to SmartThings from Google Home, or go with Amazon Alexa over Apple HomeKit, any Matter-enabled devices can come with you. Full article here… Founded 10 years ago on Kickstarter, SmartThings is one of the only standalone consumer smart home hubs from the early days of the DIY smart home boom that's still alive and kicking. The SmartThings hub is one of the few consumer-level devices with multiple radios in it, including Wi-Fi, Zigbee, and Z-Wave, allowing it to control a much wider range of smart home devices. It also works with cloud-to-cloud software services and is one of the most compatible smart home platforms. There's voice assistant support, too, for both Amazon Alexa and Google Assistant as well as Samsung's Bixby. It was acquired by Samsung in 2014. Since the acquisition, Samsung has moved away from manufacturing any SmartThings hardware, offloading both the standalone hub and many of the sensors to device maker Aeotec. The company has said it's focusing all efforts on the SmartThings app and supporting Samsung's connected products through software. The following are questions to Mark Benson, the newly appointed Head of SmartThings US, Samsung's home automation arm What is the future for the SmartThings hub with Matter on the horizon? The standalone SmartThings V3 Hub and the Aeotec SmartThings Hub will be updated to support Matter when it launches in the fall. SmartThings is getting integrated more deeply across the Samsung portfolio, with SmartThings Hub software built into select 2022 Samsung Smart TVs, Smart Monitors, and Family Hub refrigerators. These devices will also allow users to connect a wide variety of existing smart home devices, as they will be updated to get Matter as a controller support, as the new standard becomes available. We also plan to support Matter as a controller on our SmartThings Hub V2. This will enable our existing users to connect and control Matter devices. Will the built-in hubs have any low-power wireless radios, as the standalone hubs do? What about Thread? Low-power wireless protocols are a crucial part of the Matter standard and will definitely come to the Samsung SmartThings products with built-in hub functionality. More details to come later on actual implementation of Thread technology, but Thread's really important to us. Communication with Zigbee devices will be possible through the SmartThings Dongle, allowing connectivity to a wide range of smart home devices. You say Samsung is integrating Matter as a controller — does this mean that Samsung's connected devices (washing machines, robot vacuums, TVs, etc.) will not be exposed to other Matter controllers (such as Amazon Alexa or Apple HomeKit)? This year, we will focus our efforts on bringing Matter as a controller to multiple surfaces across the Samsung portfolio. This means most 2022 Samsung Smart TVs, Smart Monitors, and Family Hub refrigerators. SmartThings Hubs will not act as a Matter bridge, so non-Matter devices will not be bridged or exposed to other Matter controllers. That said, Matter-enabled SmartThings hubs will continue to support existing devices and protocols (e.g. Zigbee, Z-Wave) to provide SmartThings customers with flexible connectivity options. Where do you see Matter taking SmartThings? With connectivity becoming more standardized, where SmartThings competes in the future will be different. The user experience is the competitive space that will differentiate platforms and companies — things around use cases in the home, cooking, taking care of your pets, managing energy usage, setting the lighting just right, and locking the doors at night. Having those things just work and be simple and easy to understand so that users can control their homes and manage their homes well is why we're excited about Matter.
LIVE from NRB 2022! Matt interviews Gil McMillan and Mark Benson with the Museum of the Bible in Washington, D.C. This is a great new attraction, opened in 2018 with significant contribution from the Green family (of Hobby Lobby fame). This was an impromptu interview based on new contacts made at the first full day of the National Religious Broadcasters Convention. Museum of the Bible website: https://www.museumofthebible.org/ For more information about Christian Crusaders, the ministry under which The CC Podcast is produced: https://christiancrusaders.org/ (https://christiancrusaders.org/) To listen to The CC Podcast: Daily Dose Devotions, where we're currently going through an overview of the Bible each day, https://christiancrusaders.org/ccpod-daily-dose (click here). To listen to our weekly radio broadcast, The CC Broadcast, which has aired for over 85 years, and which features a 30 minute worship service, including music and preaching, https://christiancrusaders.org/the-cc-broadcast (click here). Thanks to Andrew, our Technical Director, and Terri, our intro/outro announcer! Music by https://pixabay.com/users/lesfm-22579021/?tab=audio&utm_source=link-attribution&utm_medium=referral&utm_campaign=audio&utm_content=5878 (Lesfm) from https://pixabay.com/?utm_source=link-attribution&utm_medium=referral&utm_campaign=music&utm_content=5878 (Pixabay)
U.S. dairy exports outperformed in 2021 thus far. While that would have been remarkable in its own right, it was all the more amazing given the port, shipping and trucking obstacles exporting companies encountered along the way. In the latest episode of The Dairy Download, we talk with two experts keeping up a steady flow of shipments despite snarls at U.S. ports.First up is Derik Toy, Director of Supply Chain at DairyAmerica, the world's largest milk powder marketer. He discusses the company's struggles with getting products to customers on time, and how DairyAmerica is reconfiguring its supply chain to overcome those issues. He also gives his outlook on when congestion and delays might ease.Next, we speak with Mark Benson, Chief Procurement Officer and Vice President of Government Affairs and Global Responsibility at Leprino Foods. Utilizing different ports, establishing new logistics hubs and adding labor – all are strategies the company is adopting to help keep its products moving. What else needs to happen to ease port congestion? Benson offers his thoughts.Today's episode is sponsored by the Kansas Department of Agriculture. "Ready to expand your dairy processing into the premier dairy frontier? There is room to grow in Kansas, the center of it all. Contact dairyinkansas.com." If your company is interested in sponsoring a block of episodes of The Dairy Download, contact IDFA's Melissa Lembke at mlembke@idfa.org. Questions or comments about the show? We want to hear from you. Send a note to dairydownload@idfa.org and your feedback could be included on a future episode.
One of the most important museums in our nation has been established only five blocks from the Capital building in Washington DC, the museum of the Bible. Join Pat and his guest Mark Benson as they share about this exciting museum that presents the history of the Bible but also its importance in the history of our nation and the nations of the world.
One of the most important museums in our nation has been established only five blocks from the Capital building in Washington DC, the museum of the Bible. Join Pat and his guest Mark Benson as they share about this exciting museum that presents the history of the Bible but also its importance in the history of our nation and the nations of the world.
Rob Blackburn, CEO of Blackburn Labs & Special Guest Dr. Mark Benson, Director - Preventative Cardiology at Beth Israel Deaconess Medical Center - Discuss a joint AI project focused on cardiology patient care. You are not going to want to miss this episode as Rob and Dr. Benson share how a new App that Blackburn and Beth Israel Deaconess Medical Center are jointly developing focused on predictive and preventative treatment of high blood pressure can potentially revolutionize Evidence Based Blood Pressure Care.John Provides Guest Introductions: 00:37 - 3:15Rob talks about AI failure rates and why they seem to happen: 6:15 - 7:30Bill tee's up a discussion about the joint project & Dr. Benson provides an overview and scope : 8:10 - 10:56Rob gives a detailed view of the App that they are developing and how life changing it can be: 13:46 - 14:45Dr. Benson discusses how the App gains acceptance and adoption and how it's distributed : 14:50 - 16:50Rob and Dr. Benson discuss potential barriers that could become hurdles to making an App like this, and how they get past them: 16:50 - 22:05Bill asks about about what Rob and Dr. Benson see the future of Healthcare as it pertains to AI: 16:50 - 27:20Dr. Benson shares why Doctors are going to embrace this type of AI technology as it will provide the data that Doctors can TRUST. It's an App that actually delivers data that Doctors need as well as providing transparency as to how the App came to a certain conculsion : 27:30 - 30:20How to reach Rob and Dr. Benson:www.blackburnlabs.com (all contact info on site)www.bidmc.harvard.eduClosing remarks: 30:08Bob Miller Intro with Music Fade
You're listening to the Westerly Sun's podcast, where we talk about the best local events, new job postings, obituaries, and more. First, a bit of Rhode Island trivia. Today's trivia is brought to you by Perennial. Perennial's new plant-based drink “Daily Gut & Brain” is a blend of easily digestible nutrients crafted for gut and brain health. A convenient mini-meal, Daily Gut & Brain” is available now at the CVS Pharmacy in Wakefield. Now for some trivia. Did you know that Rhode Island native, Ronald Champagne, served as the interim president of Roger Williams University from 2010 to 2012 before taking the position at Elmira College. Now, for our feature story: As a minister Mark Benson knows there are times when what is called for is perseverance toward a goal, even when it seems unattainable or the path strewn with obstacles. He says the story of the Joy Fellowship Church in Bradford, where he serves as pastor, is an example. About 14 years ago, shortly after Benson became a minister, he said he became convinced that his congregation belonged on Bowling Lane. The only trouble was the only church building on the street was the still active but fading Niantic Baptist Church. "We planted this 14 years ago, but this building wasn't available, but we always knew this is where we would be," Benson said in a recent interview while sitting in the sanctuary of what is now the Joy Fellowship at 17 Bowling Lane. From those days of uncertainty, the Joy Fellowship has grown to a congregation of about 125 and has more than doubled the physical size of its building. The building is open seven nights per week for music, prayer, and substance-abuse recovery activities, and the congregation recently moved its bustling food pantry to a new location a few doors down from the church. "We're growing like crazy. Everything has changed radically," Benson said. When Benson met with officials from the Niantic Baptist Church and American Baptist Church, he essentially asked them to make the same leap of faith that he was making. "I would tell them, 'We have no money but I believe I have word from God.' They were gracious," Benson said. According to Benson, his congregation came up with funds along the way and then unsolicited, perfectly timed donations arrived just as promised payments to American Baptist Church came due. Eventually, the Joy Fellowship completed the transaction and bought the building. Since acquiring its new home about nine years ago, Joy Fellowship has renovated and expanded the building from its original footprint of less than 3,000 square feet to its current 10,000 square feet. In late 2020, the church opened a food pantry in its basement. The response and need has been so steady that the pantry was recently moved to the community center building at 70 Bowling Lane which the church was given by Origen Property Investment. Benson said the property investment company gave the building to the church when one of its officials witnessed efforts the church was making on the street. "He was perplexed with me and said, 'Why are you guys here?' I said because our vision was always to be part of the community. We don't want to be an organization where people come in every week on Sunday. My vision is that this building will be open every night of the week, and it is now," For more information on all things Westerly, check out this story and more at thewesterlysun.com Are you interested in a new opportunity? You're in luck! Today's Job posting comes from the United States Postal Service in Rockville. They're looking for a full-time sales, services, and distribution associate. The job performs a variety of important functions. Pay starts at $18.49 per hour. If you're interested and think you'd be a good fit for the role you can apply using the link in our episode description. https://www.indeed.com/l-Westerly,-RI-jobs.html?vjk=b09cec8dcc0241b2 Today we're remembering the life of Nora Luther of Westerly who peacefully departed on June 25, 2021, at the age of 95. She is survived by her daughters and her son, seven grandchildren, 11 great grandchildren and many nieces and nephews. Mrs. Luther served as the credit manager for the Westerly Sears Roebuck Co. store. She later became the assistant to the manager at the Waterford Crystal Mall Sears store. She was an active member of the St. Pius X parish in Westerly serving on many committees. Thank you for taking the time today to remember and celebrate Nora's life. That's it for today, we'll be back next time with more! Also, remember to check out our sponsor Perennial, Daily Gut & Brain, available at the CVS on Main St. in Wakefield! See omnystudio.com/listener for privacy information.
One of the most important museums in our nation has been established only five blocks from the Capital building in Washington DC, the museum of the Bible. Join Pat and his guest Mark Benson as they share about this exciting museum that presents the history of the Bible but also its importance in the history […]
What distinguishes a Christian business from other businesses? What are the hallmarks that characterize a Christian in the business marketplace? Join Pat and his guest businessman Mark Benson as they share the how Christians can do business for the glory of God.
What distinguishes a Christian business from other businesses? What are the hallmarks that characterize a Christian in the business marketplace? Join Pat and his guest businessman Mark Benson as they share the how Christians can do business for the glory of God.
What distinguishes a Christian business from other businesses? What are the hallmarks that characterize a Christian in the business marketplace? Join Pat and his guest businessman Mark Benson as they […]
What distinguishes a Christian business from other businesses? What are the hallmarks that characterize a Christian in the business marketplace? Join Pat and his guest businessman Mark Benson as they share the how Christians can do business for the glory of God.
Welcome to episode three of our Hoop Heads Podcast Series called "Mentality with Dwayne Killings - Season One at UAlbany" The series will document Dwayne’s first year as the Head Men's Basketball Coach at the University of Albany. We plan to record and release 2-4 episodes per month with Dwayne and/or players, coaches, administrators, media members, and others associated with the Great Danes Basketball Program to get an inside look at what being a first year head coach at the Division 1 level is all about. Get ready to go behind the scenes with us as we talk with Dwayne Killings, UAlbany Athletic Director Mark Benson, & Deputy AD Vic Cegles about the process that led to Dwayne’s hiring as the Head Men’s Basketball Coach at the University at Albany. Website - https://ualbanysports.com/sports/mens-basketball (https://ualbanysports.com/sports/mens-basketball) Email - killingsdwayne@gmail.com Twitter - https://twitter.com/CoachKillingsDK (@CoachKillingsDK) Visit our Sponsors! https://www.drdishbasketball.com/ (Dr. Dish Basketball) Mention the Hoop Heads Podcast when you place your order and get $300 off a brand new state of the art Dr. Dish Shooting Machine! https://aryse.com/ (Aryse) As the first exo-performance company, ARYSE makes products that mimic and strengthen the way the body works. Click the link for team pricing. https://www.snap-raise.com/ (Snap-Raise) Safe, Secure and Powerful Digital Fundraising for Groups and Teams http://www.fastmodelsports.com/ (Fast Model Sports) Use Code SAVE10 to get 10% off the number one play diagramming software for coaches https://pgcbasketball.com/ (PGC Basketball) 100 Basketball Camps. 30 States. 2 Countries. PGC offers basketball camps and training for dedicated players of all positions and coaches at every level. Twitter Podcast - https://twitter.com/hoopheadspod (@hoopheadspod) Mike - https://twitter.com/hdstarthoops (@hdstarthoops) Jason - https://twitter.com/jsunkle (@jsunkle) Network - https://twitter.com/HoopHeadsPodNet (@HoopHeadsPodNet) Instagram https://www.instagram.com/hoopheadspod/ (@hoopheadspod) Facebook https://www.facebook.com/hoopheadspod/ (https://www.facebook.com/hoopheadspod/) YouTube https://www.youtube.com/channel/UCDoVTtvpgwwOVL4QVswqMLQ (https://www.youtube.com/channel/UCDoVTtvpgwwOVL4QVswqMLQ) Support this podcast
UAlbany Athletic Director Mark Benson takes us through past, present and future in college athletics as well as his relationship with Cuddy. There are some twists and turns, both in the profession and personally, and "back roads Benson" is here to tell us all about it! Reach out / Follow us: FB: @CuddyAndTheKuge IG: cuddyandthekuge Email: cuddyandthekuge@gmail.com We love hearing from our fans!
In this episode we sit with two industry veterans, guest host, Dr. Beth Hagan and Mr. Mark Benson, who discuss the changes that have taken place in community association management through the decades. Dr. Beth Hagan, M.Ed., MBA and Ph.D., has more than twenty-five years' experience in developing and delivering educational programs for literally thousands of community association board members and managers throughout Florida. She created CAMP, the Community Association Managers Program; CAOF, the Community Association Officers Forum; CEUs for CAMS and distance education classes for CAMs and board members through the company she recently sold, Education Pathways. Mr. Mark Benson has more than forty years' experience in community association management. He is the previous owner of an accredited association management company; one of the first CAMs to be licensed in the State of Florida; a legislative consultant; educator and expert witness in matters that relate to association management. He served as a member of the 2008 Florida House Select Committee on Condominium and Homeowner Association Governance drafting legislative changes to the Florida Condominium Act, Chapter 718 of the Florida Statues. He is currently an active county court mediator in association disputes.Episode Notes:Producer: Kevin S. Konecny, CAMEmail: kevin@educationpathways.bizWeb: http://www.educationpathways.bizGuest Host: Beth Hagan, M.Ed., MBA , Ph.D.Founder and Past Owner, Education PathwaysEmail: bhagan7@aol.comGuest: Mark Benson, CAMEmail: Mark@MarkRBenson.com
[As we reset for season three of The Jules Show Podcast, Producer Anne, Editor Jeff and Jules have picked their favorite podcasts from the past. This week, it's Jeff's pick which originally posted July 24, 2019] Let's face it - when you get right down to it, we're all a bunch of broken toys. We're sinners, with lot's of issues and hard as we may try to do the right thing, we just keep messing up. If you're anything like me, you scratch your head sometimes, because on the one hand, you know God doesn't waste anything in our lives, but on the other you're sitting there thinking "Lord, how are you going to use this disaster in my life for your glory?" My friend Mark Benson wondered this, too. After his infant daughter died at 90 days of life, and his marriage subsequently ended in divorce, Mark was struggling to see what God was doing with his personal tragedy. In my podcast interview with Mark, he shares with me just how God redeemed his personal brokenness and placed on his heart a passion to lead men's ministry in an effort to help and disciple other hurting and broken men. Click and listen to my podcast interview with Mark Benson.
Fans On The Run: A Podcast Made By, For And About Beatles Fans
A splendid time is guarenteed for all, with this special edition of Fans On The Run. We are not only joined by Mark Benson, co-founder of "1964 The Tribute", but also Ardy Sarraf, co-founder of "The Fab Four"! Join host Ethan Alexanian for this "tribute-twofer" edition of Fans On The Run!
Mark Benson, CEO of Academy Award winning VFX house/creative studio, MPC, talks to Broadcast Tech editor Jake Bickerton about the changing needs of commercials producers during lockdown. With Covid-19 severely limiting options for live shoots and with the tone of advertising messages necessarily adjusted to be appropriate for the global circumstances we're living through, there are many challenges facing content creators. MPC is seeing a shift to CG/VFX work to replace what might have previously been live components, and Benson talks about how it is collaborating with clients to ensure they get the most out of this approach, and that its honed to suit their needs and budget. He also talks about the impact of lockdown on MPC, both from a practical and business point of view, and also how its Shanghai office has all but reverted back to business as normal after the lockdown was lifted in China.
Show Notes: https://wetflyswing.com/ritz We dig into fly fishing for shad, alligator hunting and the Ritz-Carlton with Mark Benson. Mark walks us through the steps to catching shad along with some other shenanigans including the alligator hunt. Shad fishing has a lot of similarities to steelhead fishing so let's dig into it. Show Sponsors Hosted Fly Fishing Trips with Dave: https://wetflyswing.com/destination Show Notes with Mark Benson Flip Pallot was on the podcast in episode 70 and told the story of how he lived through the hurricane in 1992. Mark is the head guide for the Ritz Carlton and for bass fishing on the Ritz' properties. We talk about the shad's life history here and what a good run and day of fishing is like. The best flies look like an anemic crazy charlie. Here's the standard crazy charlie video. Mark notes the Delaware River and shad fishing. There are a lot of fly fisherman using sinking lines in this area with the deep and heavy water. Mark's central Florida fly shop that caters to shad. I noted the John McCloskey episode and how John puts together the pre trip in Georgia for Alaska. Mark likes a G Loomis for his trout spey games. A Founding Fish by McPhee is a great resource to check out for Shad. Shingle Creek is the headwaters of the Florida Everglades and Mark's primary stream he fishes. We talk about the golf/bass fishing or fish and chips aka bass and birdies. The course is open to the public so if you are into golf and fly fishing this is the spot. The Beatles over Elvis and Mexican food are Mark's goto random calls. A New Earth by Eckhart Tolle is all about focusing on the present. You can reach Mark at Mark Benson Outdoors. Videos Noted in the Show The Crazy Charlie Conclusion with Mark Benson We get into everything from alligator hunting to the easy steps to getting into some amazing shad fishing action. This one was one of the fun ones as we get into some random topics including golf and bass fishing. Show Notes: https://wetflyswing.com/ritz
Let's face it - when you get right down to it, we're all a bunch of broken toys. We're sinners, with lot's of issues and hard as we may try to do the right thing, we just keep messing up. If you're anything like me, you scratch your head sometimes, because on the one hand, you know God doesn't waste anything in our lives, but on the other you're sitting there thinking "Lord, how are you going to use this disaster in my life for your glory?" My friend Mark Benson wondered this, too. After his infant daughter died at 90 days of life, and his marriage subsequently ended in divorce, Mark was struggling to see what God was doing with his personal tragedy. In my podcast interview with Mark, he shares with me just how God redeemed his personal brokenness and placed on his heart a passion to lead men's ministry in an effort to help and disciple other hurting and broken men. Click and listen to my podcast interview with Mark Benson.
Den e episodio aki Career IQ ta combersa cu Mark Benson Denz un entrepreneur hoben na Aruba cu ta comparti cu nos su reto nan como commerciante pero tambe duna tips pa esnan interesa den lanta na propio negoshi. Sin lubida e segmento di Surviving 8-5 bou guia di nos psicologo Mayrene Ras-Croes.
Mark Benson, CEO of global creative studio MPC and John Payne, Managing Director of RSA Films, Asia, discuss sources of new directorial talent, the kind of film and video content brands should be thinking about in a multiplatform, multichannel world and the embarrassment of agreeing to dress in bondage gear for a shoot.
In this sermon given by Mark Benson we continue the "Love by the Book" sermon series. Not all anger is sin, but there is a sinful anger that harms us and those around us. God gives us what we need to defuse sinful anger and not be controlled by it.
In this sermon given by Mark Benson we continue the "Love by the Book" sermon series. Not all anger is sin, but there is a sinful anger that harms us and those around us. God gives us what we need to defuse sinful anger and not be controlled by it.
In this sermon given by Mark Benson we continue the "Love by the Book" sermon series. Not all anger is sin, but there is a sinful anger that harms us and those around us. God gives us what we need to defuse sinful anger and not be controlled by it.
In this sermon given by Mark Benson we continue the "Love by the Book" sermon series. Not all anger is sin, but there is a sinful anger that harms us and those around us. God gives us what we need to defuse sinful anger and not be controlled by it.
Jane Ferguson: Hello, I'm Jane Ferguson and you are listening to Getting Personal: Omics of the Heart, the podcast from Circulation: Cardiovascular genetics, and the functional genomics and translational biology council of the AHA. This is episode ten, from November 2017. November is always a big month for AHA and the annual Scientific Sessions were held in Anaheim, California, November 11th through 15th. For those of you who were able to attend, hopefully you came away feeling refreshed and invigorated and with your desired level of Disney merchandise. For those of you who could not attend, or who didn't make it to all of the genomic sessions, this month's episode should catch you up. For the past several years, the FGTB Council has been organizing boot camps at AHA sessions to give people a chance for hands on learning in a flipped classroom model. This year was no exception and in addition to a clinical genomics boot camp focused on patient centric genomics including single gene testing, whole genome sequencing and pharmacogenomics there was also a new boot camp focused on tackling big data network systems analysis for high input data interpretation. These boot camps are always very well attended and popular, so if you're interested in attending one next year, make sure to get in early and sign up during registration. There was also a hands on session in collaboration with the AHA's Precision Medicine Institute to teach people how to use the precision medicine platform to further their research. In addition to this, there was a full day of programming related to precision medicine in the precision medicine summit, which is held on the Tuesday of Sessions. That covered topics ranging from big data, electronic health records, collaborations and the All of Us initiative to rapid fire reports from ongoing consortium, large scale analysis to disease specific approaches in cardiomyopathy. We were planning to have an in depth focus on the Institute for Precision Cardiovascular Medicine in a future podcast episode, so stay tuned for more on that coming soon. There were a number of individuals who were recognized for their contributions to science and we would like to congratulate all of these outstanding individuals. The FGTB medal of honor was awarded to Stuart Cook from the Duke National University of Singapore. The FGTB mentoring award was awarded to Robert Gerszten from Beth Israel Deaconess Medical Center. The FGTB distinguished achievement award went to Sekar Kathiresan from the Broad Institute. And the functional genomics and epidemiology mid-career research award went to Kiran Musunuru from the University of Pennsylvania. Congratulations to all of these. One of the highlights for the FGTB council at sessions is the FGTB young investigator award. This award celebrates early career investigators and recognizes outstanding research in basic science, populations science, genetic epidemiology, clinical genetics and translational biology. Four finalists presented their research on the Sunday afternoon sessions and I had the chance to chat with all four of them before and after their presentations. So listen on for a behind the scenes over view of the finalists research and the announcement of the winner. Mark Benson is a cardiology fellow at Brigham and Women's Hospital and is working on post-doctoral research at the Beth Israel Deaconess Medical Center in Boston with Dr. Robert Gerszten. His talk was entitled "The Genetic Architecture of the Cardiovascular Risk Proteum." Mark Benson: My name's Mark Benson. I'm just finishing up a cardiology fellowship at Brigham and Women's Hospital and am in the middle of post doc in Robert Gerszten’s lab at Beth Israel. Jane Ferguson: Great, and congratulations on being chosen as a finalist for the FGTB Young Investigator Award. We would love to hear a little bit more about what you’re working on and what you're gonna be telling us. Mark Benson: Yeah, absolutely. So the goal of the project was really to integrate proteomic data with genomic data, with the idea that we may be able to use the overlap between those data sets to identify potentially novel biological pathways that underlie very early cardiovascular disease risk. And the thinking behind that was that the lab had just finished up applying DNA-aptamer-based proteomic platform to profile over 110 proteins and the Framingham-Offspring Cohort and from that work, we had identified a very specific signature of 156 proteins in plasma that were each very strongly associated with cardio-metabolic risk. The idea was while those associations were very strong, it was unclear if we were capturing cart or horse or how these associations were fitting together. We wanted to incorporate the genomic data to try to get a better handle on that, to try to connect those pathways to see how these proteins might actually associate with the end phenotype of risk. Jane Ferguson: It's a sort of Mendelian randomization-esque. Mark Benson: Exactly, yeah. So what we were able to find in doing this, we were able to use peripheral blood samples from participants at the Framingham-Offspring study. With a validation in participants of the Swedish Malmo Cancer and Diet Study. Then we did protein profiling using commercial DNA aptamer platform, soma scan. What we were able to find is we were able to detect very strong associations between these circulating cardio metabolic risk-proteins and genetic variance. What was fascinating was we were able to see many things. We were able to start mapping where are these associations, where are these genetic variance in relation to, for example, the gene that's coding the protein that we're measuring. That had some interesting implications because for about half of the protein that had significant associations, we could track those genetic variance back to the gene. It was coding the protein that we were measuring, which was interesting because it's validating the specificity of the proteomic platform that we're using. Jane Ferguson: Right that's nice, because so often you found a gene that's nothing related to what you think it's going to be so it's nice actually the gene you expect. Mark Benson: Yeah, it's very reassuring too when you're looking at rows and rows and rows of data. When the top association of the p value of 10 in the minus 300 is the actual gene you thought would be coding the protein that you're measuring. So that was very reassuring, but we also found dozens and dozens and dozens of associations that were totally unexpected and that may point to completely unexplored biological pathways in cardiovascular disease. So that was obviously very exciting. That actually led us to do two things. One was to make all these data available publicly on dbGaP because as a resource for cardiovascular research there is just way too much data for one group or a handful of groups to digest. The other thing that was fun about the project, is we were able to take one association that was particularly interesting for a number of reasons and experimentally validate it in a tissue-culture model. Jane Ferguson: So how did that work? Mark Benson: So this was an interesting challenge where we all of a sudden got all of these hits back, which was probably to be expected, but to try to figure out which of these dozens and dozens and dozens of new, unexpected hits, what do you do? There was one hit, one association, that was particularly strong and it was between several variance around this gene. That's a phosphatase called PPM1G. It's a transcription factor. These variants, which was interesting, were associated with several different circulating cardio metabolic risk proteins. So our idea was, isn't that interesting? Is it possible that this is mapping to some central regulator? And so it fit that that would be ... that the nearest gene to these variants was a transcription factor and could be a central regulator. What made it more interesting to us was that several variants in the GLGC had recently been described that were highly associated with circulating levels of total cholesterol and triglycerides and they were located around this PPM1G locus as well. The association between those variants and circulating cholesterol didn't have a clear biological connection. So what our work had shown is that those same variants were associated with circulating levels of apolipoprotein E. So wouldn't that be interesting if these variants mapped to PPM1G, the transcription factor, this PBM1G in turn regulated circulating apolipoprotein E and that would provide some insight into the biology behind the GLGC findings. So sure enough we were able to knock down PPM1G using SRNA and hepatocytes and then see that that led to a significant down regulation of the transcription of Apo-B and extra-cellular presumably secreted Apo-B in this model, which is kind of a nice proof of principal that this idea of integrating proteomics and genomics may lead to some novel biological pathways. Jane Ferguson: Yeah, it's really interesting. So what's next. There are probably a lot more associations that you're going to have to go after? Mark Benson: Yeah, I think that what this showed us is that this seems like a powerful tool. Joining these orthogonal data sets to find new pathways and so we're continuing to pursue that with an increasing number of proteins for example, so we're doing genome-wide association studies and x-gamma rays. We've gone from 156 to 1100 to 1300 and are now going beyond that and so as those numbers get higher, you start to see these central nodes come together and more interesting targets and potential pathways. It's also interesting to use these data to find new associations or new tools that you would never think to look for as ways to modulate protein levels. So you can imagine, for example, one thing that we've been exploring for the last few months is can we identify, for example, SNP associated with an interesting circulating protein. That SNP maps to an enzyme or some other druggable mechanism and very preliminary studies, it seems like the answer is probably yes, but there is still a lot of work to be done. Jane Ferguson: Well that's cool. That sounds really interesting. Mark Benson: Yeah, I think the key thing is that all these data will soon be out there and so it's a very rich data set and I think there are many ways that we could use the data. Jane Ferguson: So is that the genomic data and all the proteomic data or it's the summary of the those associations? Mark Benson: All the genomic data, all the proteomic data and the associations as well. You can do the associations yourself if you'd like to. Jane Ferguson: We can find that dbGaP. Awesome, well thank you for talking to us. Mark Benson: Thank you. It's been fantastic. Jane Ferguson: Congratulations again. Mark Benson: Thanks so much. ... Jane Ferguson: Jenny Lin is an instructor at the University of Pennsylvania, working with Dr. Kiran Musunuru. Her presentation was entitled, "RNA binding protein A1CF Modulates Plasma Triglyceride Levels through Transcriptomic Regulation of Stress-Induced BLDL Secretion". Jenny, can you take a moment to introduce yourself? Jenny Lin: Yes, hi. Thank you for this opportunity to participate. I'm Jenny Lin. I'm an instructor of medicine at the University of Pennsylvania, a nephrologist by clinical training, but training in cardiovascular research in Kiran Musunuru's lab. Jane Ferguson: So congratulations for getting selected as a finalist for the Young Investigator Award. We'd love to hear a little bit more about what you've been presenting and what you've been working on. Jenny Lin: Thank you. So basically, what I've been working on over the past year is functional follow-up of this A1CF locus, which is a novel locus for triglycerides. So say Sek Kathiresan's group recently published in Nature Genetics and x and y association study on plasma lipids involving more than 300,000 individuals. One of the key findings from that study is this strong association between a lo-frequency coding variant and elevated plasma triglycerides. So we wanted to delve more deeply into the biology for why we have that genotype/phenotype connection. One of the key things that we wanted to do was ... A1CF is not a stranger to lipo-protein metabolism, but we wanted to see what else it may be doing outside of its canonical role of facilitating the editing of Apo-B messenger RNA. It really took us on a little bit of a wild journey using different unbiased approaches to try to figure out some of the mechanisms that could be behind it. Jane Ferguson: So you had to do a lot of different types of experiments to really get at this question. Jenny Lin: Yeah. So again, one thing we wanted to see was: if you lose A1CF function, whether or not you would have differences in Apo-B 100-B48. We actually found that A1CF isn't even needed for that editing reaction and that our mice that we were able to create with crispr cas9 genome editing, so knocking in the mutation and knocking out the gene, actually have the phenotype even though they don't have changes in editing. But what surprised us was that we know that A1CF as an RNA binding protein binds Apo-B transcript, yet it somehow does not alter transcriptional abundance of the Apo-B messenger RNA. And it has nothing to do with Apo-B synthesis so we basically had to think, what is A1CF doing outside of Apo-B biology? We found that you have A1CF loss of function, you have increased triglycerides secretion. There is more Apo-B secretion, but that seems to be a downstream effect of other processes going on in the cell and to really try to figure out what those processes are, we had to take an unbiased approach using enhanced clipseek to figure out binding targets and also doing some transcriptional profiling with RNA sequencing and found that it's not necessarily regulating that transcriptum on a differential expression level, but there are some key alternative splicing events as well as messenger RNA binding to affect translational efficiency of some key targets that could be driving the biology. Jane Ferguson: That's really interesting and you wouldn't have been able to find that by just looking at levels of protein or levels of mRNA, you really had to do these additional clipseek and some experiments to really get at this splicing. Jenny Lin: Yeah, so it's been interesting. Clipseek is not as commonly performed method, so we had to collaborate with some brilliant people over at UCSD, to help us facilitate this. But again, finding that A1CF binds many more transcripts than Apo-B itself is a novel finding and the fact that it can regulate alternative splicing is also a very novel finding as well. Jane Ferguson: So what was the most challenging part of this whole project? Jenny Lin: I think the challenging part was that when we saw there wasn't necessarily a direct effect on Apo-B abundance and having to then cast this wide net and then figure out from all of the different unbiased data we have and integrating it find different pathways that may be relevant. In this case, it may all be relevant to ER stress, which is a field that is a little bit controversial in VLDL secretion in terms of directionality, but certainly is important in the biology. Jane Ferguson: So is that something that you're going to have to start doing in the future? Are you going to start looking at ER stress or what kind of other experiments do you think you're going to keep doing to move this project forward? Jenny Lin: Yeah, so actually, I think focusing in on A1CF as an RNA-binding protein and pursuing some of these additional targets will also be relevant, so I think in terms of ER stress, we could be looking at different targets, but there other processes going on in the cell that's mediated by A1CF, that could contribute maybe doing some isoform specific studies just to really prove that these alternative-splicing changes are driving some of the biology. There's a lot of work to do as I would joke to anyone on study section listening to this, perhaps four to five years of work for an RO1. Jane Ferguson: Sounds very appropriate. Jenny Lin: Yeah, there's a lot of exciting work to do. A1CF is actually also a locus for other cardio-metabolic relevant traits such as uric acid, gout and kidney function so there could be something very interesting going on. There could be cross talk among cellular processes that could lead to these different phenotypes. Jane Ferguson: Really interesting project and a lot of really great work. Congratulations again on being selected as finalist and on this really interesting paper. Jenny Lin: Thank you. Jane Ferguson: Thanks. Sarah Parker is based in Cedar Sinai Medical Center in LA and her mentor is Dr. Jenny Van Eyk. The title of her presentation was "Identification of Putative Fibrous Plaque Marker Proteins by Unsupervised Deconvolution of Heterogeneous Vascular Proteomes ". And I apologize in advance for the quality of this recording. The background noise wasn't that noticeable at the time, but that recording really gives you that full immersive audio experience of a busy hotel lobby. Hey Sarah. Thank you for joining us. Could you just take a few moments to introduce yourself to the audience? Sarah Parker: So I'm Sarah Parker. I'm a project scientist at Cedar Sinai Medical Center where I'm doing work to study the basic mechanisms of vascular biology of various indolent conditions. Jane Ferguson: So congratulations on being selected as a finalist for the Young Investigator Award. It's a great achievement. I'd love to hear a bit more about your project, how that started and what you found. Sarah Parker: The work that I did was under the overarching umbrella of a project called the Genomic and Proteomic Architecture of Atherosclerosis. So with this project, we're using tissues that we're able to obtain from individuals who are young and have passed away from traumatic and violent and so non-cardiovascular causes of death. Because of the presence of atherosclerosis in the population, we get this range of lesion, both fatty streak and fibrous-plaque lesions in these asymptomatic or non-diseased individuals and this gives us this opportunity to do some molecular profiling to really try to find protein-signatures of early stage plaque formation, that could ultimately and hopefully be used for biomarker development. Jane Ferguson: That's really cool and that's such a valuable sample resource. Sarah Parker: Yeah so we've essentially, in this project I was able to set up a pipeline that enabled us to do these proteomics on such a large scale, because that's actually really difficult in label free quantitative proteomics and to use other forms becomes very expensive and cost-limiting. So we were able to find a panel of proteins that we think are a putative early set of fibrous plaque markers and with this panel, we took them to see if any of these tissue derived markers would then be detectable and informative in plasma, because that's the next really big translational leap with these discovery-type data sets. Of our 58 initial candidates, we were able to detect 39 of them and about a handful 10-13 are showing informative behavior in the plasma of initial cohort of women with known coronary-artery disease. Jane Ferguson: So out of the 58 that you first found, how many of them were potentially known to be involved in disease and how many were novel? Sarah Parker: I would say, going through the list, it was probably about 50/50 in terms of background data that shows role as a biomarker, so there are a lot of apolipoproteins, which have all been characterized as potential biomarkers. There were a lot that could feasibly be linked through the literature to atherosclerosis. Most of them made a lot of sense, but having been proposed as potential biomarkers, some of them were more rare. Jane Ferguson: Were there any of them that were sort of in different directions, let's say were elevated in tissue, but then were lower in plasma? Sarah Parker: Funny you should ask. That actually has us scratching our heads a little bit right now. There were a couple of apolipoproteins that are more associated with HDL biology that we saw as being elevated in the tissue but then lower in the plasma [inaudible 00:23:34] so that's a really interesting observation so something about the role of these proteins to scavenge cholesterol and then once they're in the blood, they're cleared really quickly relative to normal, or something. So we're really trying to figure out what that biology means. Jane Ferguson: Maybe if they're building up in the tissue, that's bad. But while in circulation, they're fine. Sarah Parker: Yeah, maybe they're trapped in the circulation. We have a lot of exciting hypotheses to test along that front. Jane Ferguson: So what's next? Are you following up some of these proteins? Sarah Parker: Yep, so we have a huge discovery arm to the project where we're looking for more molecular mechanisms like why do we have these things in the tissue versus plasma and then we are working to really validate and optimize these multi-plexes in much more generalized large-scale populations to determine whether this strategy of instead of one or two biomarkers, more of a signature-style panel can be informative, especially as we try to press towards a precision medicine approach where different substratum might be informed by different protein signatures. Jane Ferguson: Right, so you might have to have a specific panel based on sex or age or race or some other demographic. Sarah Parker: Yes and to find those signatures, it's going to be very big numbers, with very accurate, careful quantitation. Jane Ferguson: So you have a lot of work to do. Sarah Parker: Yes. Jane Ferguson: Alright, well thank you for talking to us and congratulations again. Louie Wang, a cardiologist and PhD student came all the way from the Victor Chang Cardiac Research Institute in Syndey, Australia. His mentor is Dr. Diane Fatkin. The title of his talk is "A novel zebrafish model of human A-band truncated titan exhibits alternated ventricular diastolic compliance in vivo and reveals enhanced susceptibility to the effects of volume overload in mutation carriers. So thank you for joining me. Could you take a few minutes to introduce yourself? Louie Wang: So I'm Louie Wang. I'm a cardiologist based in Australia. I work and live in Sydney. I'm a PhD student at the Victor Chang Cardiac Research Institute and I'm an NHMRC (National Health and Medical Research Council and National Heart Foundation of Australia post-graduate scholar). I have previously been based at St. Vincent's Hospital. Jane Ferguson: Great. So we'd love to hear a little bit in advance of what you're working on and what you're planning to present. Louie Wang: So basically what I'm presenting is what I think is a different form of functional of genomics. What we're actually looking at is the impact of genetic changes, specific genetic change on function of the heart at an organ level. So there is a problem out there that is very common in cardiology and it's a big problem in cardiology and that is there are mutations in the sarcomere protein titan, truncating variants which actually are associated with dilated cardiomyopathy. Now they're pretty common in idiopathic dilated cardiomyopathy, present in about 15-20% of the cases depending on which cohort study you look at. But they're also widely prevalent in the general population. Somewhere between 0.3 to 1% of the general population carries this truncating variants or various forms of this truncating variant. So it's not sure whether these are disease-causing in their own right or if it's just a genetic susceptibility factor for heart failure and so what our work involves is that we actually, by chance, at St. Vincent's Hospital and at Victor Chang Cardiac Institute, two families who had the identical genetic truncation in the A-band region of his human titan gene where the individuals in the family, typically who carried the gene, typically developed systolic heart failure, which is a mild phenotype and occurred at middle age, but in two individuals, they developed severe onset accelerated disease trajectory in a very severe phenotype when exposed to conditions associated with chronic volume overload. We suspect and this was a hypothesis, not only was this genetic-truncation disease-causing, but at volume overload was disease-modifying and given that volume overload is a very common condition present in birth, a lot physiological processes like lung endurance, exercise, pregnancy as well as a lot of pathological disease states in cardiovascular disease, this was actually a very important modifiable factor. So what we did, was we created a novel zebrafish model of this human A-band truncated variant. We then studied the animals when they became adults to look at their heart structure and function and we used zebrafish echocardiography. So reversed translated all the techniques you can do in human echocardiography so they can be used in the zebrafish. What we found was, yes, this animal, or heterozygotes developed dilated cardiomyopathy but also the volume overload exacerbated this condition. So this is a phenomenon that has conserved this by four hundred million years of vertebrate evolution so this is a pretty important mechanism. Jane Ferguson: So what kind of next steps do you see for this project? Louie Wang: So one thing is that we obviously have shown that there is an association with volume overload in precipitous disease. The corollary of our work is that perhaps interventions that could reduce volume load in these genetic susceptible individuals or alternatively in people who can't avoid volume overload. Because a lot of volume overload conditions can be modifiable and perhaps this could be protective and that would have wide-ranging population benefits. Jane Ferguson: Thank you for sharing that soundbite of your work and good luck. Congratulations again on becoming a finalist. Louie Wang: Thank you. ... Jane Ferguson: Each of these four finalists gave compelling presentations of their research and the judges were highly impressed of the quality of the research and level of accomplishments of these early career investigators. Just getting selected as a finalist for this award is a huge accomplishment. But there did have to be one winner. I'm delighted to announce that Jenny Lin was selected as the 2017 FGTB Young investor award winner. Congratulations, Jenny, and thanks to all four finalists for agreeing to appear on this podcast. And that's all for this month. We'll be back at the end of December with a new episode. Subscribe to the podcast through iTunes or your favorite podcast app. to get new episodes delivered automatically and thank you for listening.
About the Show: On this episode of the podcast we sit down and chat with Mark Benson, owner and founder of Waymark Gear Co. We find out his story. We find out what made him want to quit working in the culinary arts industry and start making frameless backpacks. We find out what drives him as an individual, the backpacks he makes, what inspires him, and of course Mark shares with the listeners a few of his favorite local Utah hiking spots. Links Mentioned on the Show: Episode 158, the first time Mark Benson was on the podcast. http://www.iamsaltlake.com/episode-158-mark-benson-from-zao-asian-cafe/ Waymark Gear Co website https://www.waymarkgearco.com/ Waymark Gear Co on Facebook https://www.facebook.com/pg/WaymarkGearCo/ Waymark Gear Co on Instagram https://www.instagram.com/waymarkgearco/ Jed’s Barber Shop http://jedsbarbershop.com/ Amanda Kay Memories http://www.amandakaymemories.com/ I am Salt Lake Facebook group https://www.facebook.com/groups/1252060254810776/ Leave this podcast an iTunes review http://www.iamsaltlake.com/itunes I am Salt Lake Patreon http://www.patreon.com/iamsaltlake
Summary: Tammi Brannan speaks with Mark Benson about his business choices that enabled him to grow his company, and make it more efficient. His game-changer was narrowing his market over 15 years ago. To learn more about the prosperity movement and help you and your clients build and keep wealth visit www.TheAdvisorAdvantage.com Links in this Episode: The Summit - www.TheSummit4Advisors.com Show Notes: 00:00 Intro 01:00 Background of Mark and his company 01:35 Works with teachers in Missouri, and homeowners 03:25 We have the market calling us 03:46 What was your time frame between making the decision to narrow your market, and seeing your business shift? 05:53 Bring in value creation to gain clients 07:11 Unique ability concept- how have you implemented it? 09:20 We have unique ability teamwork- everyone does what they like best 12:56 What are the activities that you enjoy the most? 15:17 Anyone trying to grow their business should look into Strategic Coaching 17:10 If you are doing things to your unique ability, you should have more energy at the end of the day. 18:13 Explanation of: free days, buffer days, and focus days 22:00 Why it's easier to grow 10x than 2x
Join us when Mark Benson explains how Exosite is helping customers transform their traditional businesses by embracing the Internet of Things and adopting new software and strategies that allow them to optimize cost and create new revenue streams. Guest: Mark Benson, Chief Technology Officer Company: Exosite Headquarters: Minneapolis, MN Ownership: Private Contact: www.exosite.com @exosite (twitter)
University at Albany Athletic Director, Mark Benson, reviews how he analyzed the challenge of raising money for the Great Danes as a key part of his decision to pursue the job at Albany. He also covers his benchmarking process, and how he decided the opportunity was a good fit for him and his family.
Trevor Dann visits Bauer Radio's MFR in Inverness to meet breakfast host Ginno Conti and station director Dawn Murray. Plus news inc a tribute to Mark Benson and Radio Moments
E24 - FrontLine Chatter - Mark Benson on VMware Access Point by Frontline Chatter
LIVE from The Ritz Carlton Orlando Grande Lakes with Captain Mark Benson talking fishing, golf, eco-tours and product review of Stank-X-Baits January 30th 2016
In this episode of the podcast I sit down and chat with Mark Benson from Zao Asian Cafe. Find out the story of Zao and how it came to be. We also chat about how Mark got interested in photography, how he got interested in culinary arts, and of course what he enjoys about living in Salt Lake City
As a nice change of pace, we break away for a short while from our normal podcast to a segment called "What's On Your Mind" where we will occasionally select a space tweep who is willing to do an interview and get to know a little bit more about them. This time, Mark Ratterman interviews Mark Benson (@MDBenson) about his interests in space, astronomy, astrophotography, and many other interesting subjects! Host: Mark Ratterman. Special Guest: Mark Benson. Announcer: Russ Dale , Space Tweep Theme Composed by: Todd Cecilio. Special thanks to all of the members of the Space Tweep Society (http://spacetweepsociety.org ) Recorded Saturday, 10/17/2009
© 2020-2025 Ivy Podcast Discovery LLC
