Podcasts about hla dq8

Send us a textDid you know that coeliac disease affects 1 in 100 people worldwide, yet only 30% are properly diagnosed? In this episode, I'll explain what coeliac disease is, who is at risk, and why thorough testing and diagnosis are so important.In this episode, I discuss:Common signs and symptoms and why many are not related to the gut; The prevalence of coeliac disease; Three important tests for coeliac disease;Why an accurate diagnosis is crucial; Why symptoms in children are different from adults;The link between autoimmune conditions and coeliac disease;Why testing in children under 3 is not recommended;If you or someone you know is experiencing any of the symptoms discussed in this episode, it might be time to get tested for coeliac disease. And if you found this episode helpful, please share it with others who might benefit!Episode Links: Download our free Kids Gut Health e-bookBook an appointment with one of our Naturopaths This episode is proudly sponsored by my membership, the Natural Super Kids Klub. If you would like to become a member of the Klub to get more helpful resources to help you raise a happy and healthy family click here and pop your name on the waitlist. If you loved this episode, leave me a review! I would super appreciate it. Also, let me know your biggest takeaway from this episode by sending me a direct message on Instagram @naturalsuperkids or shoot me an email at jessica@naturalsuperkids.com.

Immunic Inc (NASDAQ:IMUX) chief scientific officer Hella Kohlhof joined Proactive's Stephen Gunnion on International Celiac Day, in the middle of Celiac Disease Awareness Month, to discuss the disease and the company's developments in treating it. Kohlhof explained that celiac disease is a severe autoimmune disorder affecting around 1% of the global population, predominantly females. Unlike gluten intolerance, celiac disease involves an immune reaction to gluten, leading to gut inflammation and destruction. The only current treatment is a gluten-free diet, which is not effective for all patients. Kohlhof elaborated on the disease's scientific background, highlighting its genetic association with specific HLA genotypes (HLA-DQ2 and HLA-DQ8). She explained that celiac disease is triggered by the immune system's reaction to deaminated gluten peptides, causing inflammation and damage to the gut lining. Immunic is developing IMU-856, an epigenetic modulator, to treat gastrointestinal diseases like celiac disease. IMU-856 enhances gut regeneration and strengthens the gut barrier, improving patients' conditions. Kohlhof detailed the successful completion of a Phase 1b study in celiac patients, which demonstrated the drug's safety, good pharmacokinetic properties, and positive effects on symptoms, biomarkers, gut histology, and nutrient uptake during a gluten challenge. The study confirmed the potential of IMU-856 in treating celiac disease, and further exploration of its mode of action is ongoing. #ImmunicInc, #CeliacDisease, #AutoimmuneDisorder, #GlutenFree, #HellaKohlhof, #ScientificResearch, #EpigeneticModulator, #IMU856, #GutHealth, #Phase1bStudy, #GlutenChallenge, #GastrointestinalDiseases, #Biotechnology, #MedicalResearch, #HealthInnovation, #Pharmacokinetics, #GeneticResearch, #ImmuneSystem, #Healthcare, #ProactiveInvestors #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Ever wondered why you might suddenly develop Celiac disease later in life? We're taking a deep dive into the heart of the genetic triggers at play behind Celiac disease, that can activate at any point in your life. We're unravelling the mystery behind the genes, HLA, DQ2 and HLA-DQ8, and how they play a pivotal role in developing Celiac disease. We're also shedding light on the various triggers that can ignite this disease - from personal life events like childbirth, to global pandemics such as COVID-19. Whether you're recently diagnosed, seeking answers or just intrigued by the world of Celiac Disease, this episode promises to quench your curiosity.Learn more about Ultimate Celiac System here www.belindawhelan.com/ultimateceliacsystem Join my free community and grab your copy of 11 Mistakes People Make Living Gluten Free here www.belindawhelan.myflodesk.com/11mistakesCheck out my Daily Health Tracker hereHEALTH TRACKER | The Healthy Celiac (belindawhelan.com)And I would love to connect with you on Instagram thehealthyceliacIf you have a spare moment, please pop over to Apple Podcasts and leave me a review. I'd love to hear your insights and what you enjoyed about this episode. Thank you!Music Credit bensound.com 

I asked what you wanted to know about Hashimoto’s and the questions came flying in! In this episode, I’m going to tackle half of them and tune in next week as well because I’ll answer the rest there! Hashimoto’s disease is an autoimmune disease that affects the thyroid. Like other autoimmune diseases, what happens is that the immune system gets confused and starts to see the thyroid as a threat. In other autoimmune diseases, the system attacks a different part of the body (the myelin sheath with MS, joints with rheumatoid arthritis, connective tissue with lupus). Under this attack, the thyroid can’t perform optimally and the result is often hypothyroidism.  Conventional medicine treats Hashimoto’s by only addressing the  hypothyroidism if present or waiting for hypothyroidism to begin or suppressing the immune system with medication. The functional medicine approach is to find the root cause of the Hashimoto’s and fix it. I support the functional medicine approach and it starts by understanding what’s going on first. Which is why, I’m so happy to answer your questions!   Autoimmune Triggers  There are four main triggers that can get the immune system in a tizzy. Here are the key triggers for autoimmune diseases: Food Individuals may have food sensitivities, or lack the proper enzymes or stomach bile to properly digest food. If the food we eat doesn't work for our body its a huge trigger for autoimmunity. Infection There are a variety of infections that can become chronic causing the immune system to malfunction. Toxins Environmental toxins (like those found in some cleaning products and beauty products) as well as heavy metals can serve as a trigger. Stress The immune system handles stress by shutting down other non-essential systems. Over time (especially if it’s chronic), this can be a trigger for autoimmune disease.    Question #1: What is the relationship between heavy metals and the root cause of Hashimoto's? Heavy metals are things like aluminum, mercury, arsenic, lead and they can really do a number on our system. Our bodies can handle a little bit of heavy metals but when they build up, they become a toxin (which is one of the triggers). Even copper can become a toxin if it gets out of control (usually due to a zinc deficiency). Mercury has an affinity for the thyroid, so this heavy metal (in particular) should be monitored to ensure it hasn’t reached toxic levels in the body.  There are lab tests that will determine if heavy metals might be the root cause for you. A standard hair analysis is one test but it doesn’t show both types of mercury. My go-to tests for heavy metal are the Quicksilver Scientific Tests because it includes a full heavy metal panel and looks for mercury levels in the blood, urine, and hair.  If heavy metal is a problem, then a detox using binders and herbs like Milk Thistle are often used. However, you’d want to consult with a functional medicine practitioner to make sure you’re doing the right kind of cleanse.   Question #2: What is the connection between Hashimoto’s and the adrenal glands? Stress is one of the four triggers. The adrenal glands deal with stress by producing the hormone cortisol. When too much is produced, the immune system takes that to mean that it’s an emergency putting things like thyroid production on the backburner.  Cortisol also has a relationship with TSH. When cortisol is off, TSH can be off as well and directly affect thyroid function. There is one other potential connection. The symptoms of hypothyroidism are very similar to the symptoms of adrenal fatigue (weight gain, fatigue, depression, hair loss) and so the symptoms may be misinterpreted.    Question #3: What is the true connection to EBV (Epstein-Barr Virus)?  This question sparked a secondary question involving the Medical Medium and the things he’s said about EBV being connected to everything, including attacking the thyroid before causing Hashimoto’s.  I get asked about this a lot but remember the four triggers - one of them is infection which is exactly what EBV is. There is some research that EBV can get into the thyroid gland (as well as other organs) but I wouldn’t say it’s conclusively linked. However, it is an infection which is a trigger. It’s worth noting that once someone gets EBV it’s always in the system and it can flare up due to stress, toxins, and other infections - it has the same triggers as autoimmune.    Question #4: Can you Address Food Sensitivities with Hashimoto’s? Another listener also asked about her experiences with cutting out gluten and dairy and subsequently developed other food sensitivities. (Be sure to check out the episode I did on food sensitivities for more on this)  Food is one of our four triggers, so we know there is a connection. Food sensitivities are not  typically things are born with, they develop over time. So, I  always recommend that you get tested  to see what your sensitivities are using a test that will look comprehensively at antibodies and genetics (not just the general antibody test). But also we want to look at where the sensitivities come from (before eliminating more and more foods) because if there’s inflammation in the body, you're more prone to sensitivities.  Another thing to consider is if you might have gut issues, dysbiosis, candida, parasites or bacteria. This could create a lot of inflammation in the intestines, causing leaky gut. And, if you are lacking the right enzymes or your bile is off, you may not be digesting your food which could result in food getting into your bloodstream. So, sensitivities can definitely be a trigger but you also want to make sure that it’s not your gut health (and infections) causing the issue.    Question #5: Hashimoto’s tends to run in families, especially daughters and females. Is there anything I can do to keep my daughters from getting it down the line? I love this question because there’s so much we can do to protect our children’s health. Prevention is the key when you’re dealing with any disease - especially autoimmunity. Start by considering the four main triggers.  Testing for food sensitivities early can be helpful as can genetic testing - specifically the HLA-DQ2 and HLA-DQ8 which is related to gluten which has a big connection to autoimmunity (not just Hashimoto’s).  Keep an eye on their gut healthy - especially with regards to antibiotics that can disrupt the microbiome and cause dysbiosis (which introduces another trigger - infection).  Consider a good probiotic for kids and doing a regular stool test to get a sense of their microbiome.  Toxins can be minimized by control chemicals in the home (including cleaning products and beauty products). And finally, try to help them learn how to deal with stress. I like the book The Goodnight Caterpillar: A Children's Relaxation Story to Improve Sleep, Manage Stress, Anxiety, Anger by Lori Lite and Emily Fletcher (who appeared on episode 005) has a new meditation program for kids. And, remember that kids learn from watching us, so make sure you model good stress-management skills too.    Next Episode You had more questions about Hashimoto’s disease than I could answer in this one episode! So, tune in next week for more questions and answers about Hashimoto’s and your thyroid health.  Eliminating Health Mysteries Do you know someone struggling with autoimmunity or Hashimoto’s? Share this episode with them. It could help regain their health and give them hope because the answers are out there!   Links: Resources mentioned: Enter the contest by submitting a review then letting me know on Instagram Review Health Mysteries Solved Here  My Instagram Page The Goodnight Caterpillar: A Children's Relaxation Story to Improve Sleep, Manage Stress, Anxiety, Anger by Lori Lite Ziva Meditation for Kids (Emily Fletcher)   Suggested Products Mercury Tri Test Push Catch Detox Related Podcast Episodes: The Case of Exercise Zapping Energy w/ Dr. Kasia Kines Everything You Need to Know to Interpret Epstein Barr (EBV) Results Demystifying Food Sensitivities (and What You Can do About Them) Solving the Autoimmunity Mystery w/ Inna Topiler The Case of the Soul-Crushing Insomnia w/ Emily Fletcher   Thanks for ListeningIf you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts and remember to rate and review the show! Find out more at http://healthmysteriessolved.com   PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price of the product but it helps us a tiny bit in covering our expenses.

  If you think you have celiac disease, this podcast will help you break down the necessary tests to screen and diagnosis the disease. Below are the three we touched on!   1. Bloodwork: TTG IgG & TTG IgA 2. Endoscopic Biopsy to see the damage of the villi in the small intestines. Small procedure your put under anesthesia  3. Genetic Screening: HLA-DQ2 or HLA-DQ8    At home test: https://imaware.health https://www.23andme.com   You can also follow my day to day life my IG Stories: https://www.instagram.com/servingceliacs/   https://www.servingceliacs.com

Much existing propaganda claims that African Americans do not suffer from celiac disease. Even the Gluten Free RN was surprised to find out that her adopted daughter had a genetic predisposition to the disease back in 2006, as research available at the time regarded the HLA-DQ2 and HLA-DQ8 genes to be primarily Caucasian traits. And until we take steps to conduct a mass screening, we simply don’t know how common celiac disease is among people of African descent. Today, the Gluten Free RN is exploring celiac disease in the African American population. She covers a 2006 study out of Columbia University that assessed African American celiac patients, discussing the variety of ways the subjects presented with celiac disease and the potential reasons for their poor compliance with the prescribed gluten-free diet. Nadine also considers the prevalence of celiac disease on the continent of Africa, explaining why she believes the number of celiac patients will explode with the population’s growing exposure to wheat. Listen in for the Gluten Free RN’s insight on other health issues that may point to undiagnosed celiac disease and learn how we can prevent celiac disease among the African American population with access to testing, social support and gluten-free food! What’s Discussed: The 2006 Columbia University study of celiac disease in African Americans Identified nine patients with biopsy-proven celiac disease Presented with diarrhea, iron deficiency anemia and autoimmune disorders Why patients in the Columbia study demonstrated poor dietary compliance Expense, availability and palatability of gluten-free food Lack of symptoms at diagnosis, inaccurate dietary information Nadine’s prediction around the number of celiac patients in Africa Increasing exposure to wheat will cause explosion The statistics regarding the mortality burden of celiac disease Science Daily reported estimates of 42K child deaths every year in 2011 Majority from Africa and Asia The overlap between diabetes and celiac disease Every type 1 diabetic is HLA-DQ2/8 gene carrier The health issues that may indicate undiagnosed celiac disease Type 1 diabetes, cardiac issues, stroke and heart attack Obesity (stems from lack of nutrient absorption) How to prevent celiac disease among the African American population Access to testing, social support and gluten-free food Resources: Celiac Disease and How Gluten Affects Your Skin EP011 ‘Your Skin on Gluten’ on YouTube ‘Celiac Disease in African-Americans’ in Digestive Diseases and Sciences ‘First Global Estimates of Coeliac Disease and Its Mortality Burden’ in Science Daily Neurological Disorders Associated with Celiac Disease EP012 ‘Celiac Disease in the Developing Countries: A New and Challenging Public Health Problem’ in the World Journal of Gastroenterology ‘Systematic Review: Worldwide Variation in the Frequency of Coeliac Disease and Changes Over Time’ in Alimentary Pharmacology and Therapeutics ‘HLA Typing and Celiac Disease in Moroccans’ in Medical Sciences ‘A Historical Assessment of Sources and Uses of Wheat Varietal Innovations in South Africa’ in the South African Journal of Science University of Chicago: Celiac Disease Facts and Figures ‘Adult Coeliac Disease in South Africa: An Analysis of 20 Cases Emphasizing Atypical Presentations’ in the South African Medical Journal   ‘Epidemiological and Clinical Features in Immigrant Children with Coeliac Disease: An Italian Multicentre Study’ in Digestive and Liver Disease ‘Prevalence of Positive Coeliac Serology in a Cohort of South African Children with Type 1 Diabetes Mellitus’ in the South African Journal of Child Health ESPGHAN Goes Africa Course Connect with Nadine: Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Melodies of the Danube Gluten-Free Cruise with Nadine Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Heal

The Irish are known for being lucky… But does that luck hold out when it comes to celiac disease? The prevalence of celiac disease among the Iris is 1:100, about the same as the rest of the world. And if you are a redhead of Irish descent, there is a good chance that you are an HLA-DQ2 or HLA-DQ8 gene carrier. Today, the Gluten Free RN explores Irish ancestry and celiac disease, discussing how the Potato Famine led to a change in diet for much of the surviving population. She walks us through a paper published by Irish College of General Practitioners explaining the clinical presentations and complications of celiac disease. Nadine shares her experience running the Dublin marathon and the health consequences she suffered after touring the Guinness brewery. Listen in to understand the work of the Coeliac Society of Ireland and learn about the trends in celiac disease among the Irish. What’s Discussed:  Why red hair is associated with celiac disease Tend to be HLA-DQ2 and/or HLA-DQ8 gene carriers The prevalence of celiac disease in Irish Setters Do much better on a gluten-free/Paleo diet The Irish Potato Famine Potato-based diet, little access to grains Famine from 1845-1849 One million died, many emigrated The myth that celiac disease is more prevalent in Europe than the US 30-50% of the population carries HLA-DQ2, HLA-DQ8 gene The myth that women are more susceptible to celiac disease Statistics don’t support this belief The Irish College of General Practitioners paper on celiac disease Clinical presentations, complications of celiac disease Conditions associated with increased prevalence The prevalence of celiac disease in Ireland 1:100 (matches rest of world) The appropriate testing for celiac disease and NCGS Blood test for total IgA/IgG, DGP and AGA Nadine’s experience running the Dublin marathon in 1998 Extreme edema in lower extremities The information provided by the Coeliac Society of Ireland Health ramifications of undiagnosed CD Average duration from symptoms to diagnosis (nine months) Resources: ‘Gluten-Sensitive Enteropathy in a Family of Irish Setters’ in The Canadian Veterinary Journal ‘Diagnosis and Management of Adult Coeliac Disease’ in ICGP Coeliac Society of Ireland ‘Prevalence and Incidence of Celiac Disease in Edinburgh and the Lothian Region of Scotland’ in Gastroenterology ‘Prevalence and Diagnosis’ by the Coeliac Society of Ireland ‘Coeliac Disease in Europe’ in Alimentary Pharmacology & Therapeutics ‘Escalation in the Amount of Adults Diagnosed with Coeliac Disease’ in Lifestyle Health ‘Gluten-Free Foods’ by the Food Safety Authority of Ireland ‘How Irish Diets of the Past Affect the Present’ in The Irish Times ‘Changes in Presentation of Celiac Disease in Ireland from the 1960s to 2015’ in Clinical Gastroenterology and Hepatology ‘Coeliac Disease: A Personal Perspective’ in Irish Health ‘Coeliac Disease: More Common Than You Think in Irish Health ‘Pathology and Management of Coeliac Disease’ by the Dublin Academic Medical Centre & UCD Connect with Nadine: Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Melodies of the Danube Gluten-Free Cruise with Nadine Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

Few things are as painful as losing a loved one to an overdose. Addiction is such a powerful demon, and most of us have friends or family who are facing it right now. It is easy to feel helpless, believing that there is little you can do to ease their pain. But what if a diet change could resolve the physical and psychological pain at the root of the dependency? You might be surprised to learn that gluten binds with the opioid receptors in the brain, functioning as a ‘gateway drug’ to other addictions. Today the Gluten Free RN shares her experiences with addiction and overdose during her 17-year career in the ER, explaining how she made the connection between undiagnosed celiac disease and addiction issues. She discusses the US opioid epidemic and how a mass screening for celiac disease could prevent such widespread substance abuse. Listen as she describes the morphine-like effects of gluten on your brain, the role of the microbiome in dictating cravings, and why gluten may be at the root of the pain that leads patients to self-medicate with dangerous recreational drugs. The sad truth is that 91 Americans die every day from an opioid overdose. Because undiagnosed celiac disease goes hand in hand with addiction, is it past time to get our loved ones tested. Suggest it today -- it could save a life. What’s Discussed: The recent flood of headlines regarding the US opioid epidemic How exorphins affect the brain Endorphins release chemical to make person feel good (i.e.: runner’s high) Ingest exorphins, make feel differently (e.g.: good, tired, sedate) Includes food, alcohol, pharmaceuticals and recreation medications (marijuana, cocaine, heroin, methamphetamines) How Narcan reverses a heroin overdose Binds with opioid receptors The potential connection between gluten and opioid addiction Gluten binds with same receptors in brain Addiction to gluten, dairy may be precursor to other addictions Many self-medicate with ‘comfort food’ containing wheat and dairy (i.e.: pizza, mac and cheese) The morphine-like effects of gluten and dairy on your brain Very similar to narcotics Elimination diet causes uncomfortable detox process Can take a few days, several weeks May experience fatigue, depression, abdominal pain, headaches Feel better once body clear of damaging proteins The substances patients abuse to treat pain Prescription drugs Over-the-counter drugs Alcohol Cigarettes Recreational drugs (e.g.: methamphetamine, marijuana) The symptoms of pain patients may experience due to gluten Autoimmune issues Intractable headaches Psychological, emotional anguish The data around opioid overdose in the US 91 Americans die every day 32,000 people die annually Numbers likely much higher How gluten sensitivity may lead to pain med addiction Opioid receptors may be damaged, destroyed by gluten Patient cannot absorb pain meds due to villous atrophy Need stronger meds, higher dose Common prescription meds for pain Vicodin Percocet Morphine Dilaudid Why patients turn to heroin for pain relief Less expensive to acquire Easily accessible How food can act as a ‘gateway drug’ to other addictions Celiac disease causes nutrient deficiencies Magnesium Folic acid B vitamins D3 Addictions to alcohol, cigarettes, shopping, etc. seek to fill void Eliminate gluten and heal intestines, addictions resolve Why Nadine advocates a mass screening for celiac disease HLA-DQ2, HLA-DQ8 gene carriers more susceptible to addiction issues Identification can prevent opioid addiction How ER departments treat alcoholics Banana bag (liter of saline + multivitamin, thiamin, folic acid and magnesium sulfate) Addresses nutrient deficiencies Prevent the shakes, help patient detox gradually Celiac disease may be underlying issue The power of the microbiome Tiny bacteria live in intestine Dictate what we eat, drink through cravings Communicate with brain (e.g.: yeast signals need for sugar) The mental health issues caused by untreated celiac disease that may lead patients to self-medicate Depression Anxiety Hallucinations Schizophrenia Bipolar disorder Resources: “Here’s How a Key Part of the Opioid Legislation is Not Working” in the Boston Globe “Gluten Sensitivity May Be a Misnomer for Distinct Illnesses to Various Wheat Proteins” in Scientific American “John F. Kennedy’s Pain Story: From Autoimmune Disease to Centralized Pain” in Practical Pain Management “Malabsorption of Opioid Medications” in Practical Pain Management “The Opioid Effects of Gluten Exorphins: Asymptomatic Celiac Disease” in the Journal of Health, Population and Nutrition Connect with Nadine:  Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Melodies of the Danube Gluten-Free Cruise with Nadine Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

There are a number of misconceptions about celiac disease, even within the medical community! Despite a growing body of research to the contrary, many practitioners still believe celiac disease to be strictly a gastrointestinal issue with a just a few tell-tale symptoms. It’s time to get the facts, and today the Gluten Free RN shares 21 important truths about celiac disease that you need to know.  Nadine shares her take on the list compiled by Gluten Free Works, covering the truth about who is at risk, the wide variety of neurological symptoms a celiac patient might present, and the components of an optimal treatment plan. As the most common genetic autoimmune disease in the world, it is incredibly important that we understand how gluten exposure can damage the intestines and cause debilitating nutrient deficiencies.  Nadine also explains why celiac disease often goes undiagnosed and how an astute practitioner is able to accurately interpret biopsies, antibody screenings and lab work. Get familiar with these 21 important facts about celiac disease, and become your own advocate!  What’s Discussed:  Celiac disease is the most common genetic autoimmune disease in the world Powerful as consumer group, ‘vote with dollars’ Purchasing fewer grains More and more gluten-free products available Choose grass-fed, no antibiotic/hormone meat Look for local, organic, non-GMO produce Celiac disease is the most commonly misdiagnosed disease in the world Patients often diagnosed with other disorders Gluten-free diet necessary for symptoms to resolve Celiac disease blood tests are not pass/fail Measure antibody levels Suggest how likely intestinal biopsy will discover damage 70% false negative Anti-TG2 or IgA EMA antibodies indicate gut damage Celiac disease can affect any genetically predisposed person of every race of gender and can first present symptoms at any age No one can be ruled out HLA-DQ2, HLA-DQ8 indicate genetic predisposition 30% of those diagnosed over age 60 Optimal treatment of celiac disease includes a 100% strict gluten-free diet, nutrient deficiency identification and replenishment, and education and support that meet the physical and emotional needs of the patient May need to eliminate dairy, soy, grains and legumes as well (anything that causes inflammation) ‘Find your people’ Most cases of unresponsive celiac disease are due to inadvertent gluten exposure, where the person is consuming gluten without realizing it May not exhibit symptoms when exposed to gluten (airborne, via cross-contamination) Have expert examine home environment to ferret out potential sources The average person with celiac disease has a normal body mass index Traditionally thought to be underweight Roughly 33% of celiac patients are overweight Obesity indicates malnourishment (body’s attempt to store cheap energy) Silent celiac disease refers to a person who tests positive on blood test and villous atrophy on intestinal biopsy, but exhibits no overt symptoms Roughly 50% of those diagnosed on screening exam would claim to have no symptoms Astute practitioner recognizes warning signs Celiac disease presents submicroscopic damage causing nutrient deficiencies before villous atrophy Damage can occur before endoscopy finds it Marsh 1 damage is first stage, caused by gluten Don’t wait for total villous atrophy (Marsh 4 damage) to adopt gluten-free diet Ask knowledgeable practitioner to review biopsies, antibody screenings and lab work 50% of people diagnosed with celiac disease exhibit neurological symptoms at the time of diagnosis Neuropathy (numbness or tingling in hands and feet) Seizure disorders Ticks (especially facial) Bell’s palsy Fasciculation of muscles ‘Pins and needles’ in feet Gastroparesis Constipation (paralysis of intestines) Doctors consider celiac disease to be a gastrointestinal disease Symptoms can be neurological Medical professionals must be astute, recognize all 300 symptoms Anxiety can be the only symptom of celiac disease Due to nutrient deficiencies Irritability can be sign of gluten sensitivity Celiac disease tests are not pass/fail Follow up testing should be performed if symptoms don’t resolve ‘Seroconversion’ means can test negative one day, then positive two weeks later Patient education is the most important predictor of good clinical outcome in celiac disease Find a practitioner to help develop diet for health/lifestyle Pursue body work to repair damage, strengthen body Celiac disease symptoms can be completely different among family members Celiac symptoms number over 300, affecting every system and any organ Widely varied in nature Listed in Recognizing Celiac Disease: Signs, Symptoms, Associated Disorders and Complications by Cleo J. Libonati Symptoms in celiac disease are due to inflammation and/or nutrient deficiencies from chronic intestinal damage Gluten-free diet will heal intestines, eliminate inflammation Requires time, energy and investment in best possible food Celiac disease diagnosis can take ten years or more from the time symptoms first present Frequently last disease considered by doctors (in for-profit healthcare systems) Countries with universal health care diagnose much more quickly Celiac disease affects over three million people in the US, yet the vast majority are not diagnosed Symptoms considered definitive diagnoses, treated superficially Type 1 diabetes MS ALS Lupus Sjögren’s syndrome Anemia Osteoporosis Failure to thrive Eating disorders Underlying cause (celiac disease) left untreated Exposure to gluten is the most important environmental factor in celiac disease Sooner gluten is removed, more likely to achieve full remission If gluten is never introduced, celiac disease will never develop Although celiac disease is now known to cause over 300 symptoms, the medical community has traditionally instructed doctors that celiac disease affects children, presenting symptoms of diarrhea, wasting muscles, anemia, and abdominal distention Be your own advocate    Resources: Recognizing Celiac Disease: Signs, Symptoms, Associated Disorders and Complications by Cleo J. Libonati 21 Important Celiac Disease Facts You Need to Know… Gluten Free Works Connect with Nadine:  Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Melodies of the Danube Gluten-Free Cruise with Nadine Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

You don’t have to prove to anyone that you have celiac disease proper. Because food functions as both medicine and poison, it is important to have all the facts before you get talked into a gluten challenge … and the fact is, going back on gluten after you have adopted a gluten-free diet will cause organ damage. The Gluten Free RN speaks to the motivation behind doing a gluten challenge, the consequences for celiac and gluten sensitive patients, and her work as a patient advocate to discourage people from being talked into a gluten challenge. She offers a detailed risk versus reward analysis of braving a gluten challenge, explaining how the maintenance of a gluten-free diet prevents the development of celiac disease and other autoimmune disorders. Nadine also covers the unreliable nature of celiac testing in the US, where the medical community lacks savvy in interpreting results, and explains why biopsy results are no longer considered the gold standard of celiac testing. Listen in to understand the recommended diet for those who have adopted a gluten-free lifestyle and why it requires a long-term commitment. Get armed with information and protect yourself and your family from the dangerous, irreversible consequences of a gluten challenge! What’s Discussed:  The gluten free lifestyle Involves long-term change Can’t take days off  Why you should be cautious of restaurants with a gluten-free menu Very few actually deliver gluten-free meal Employees may not understand contamination, cross-contamination  The advantages of living in the Northwest US Almost 50 designated gluten-free/Paleo restaurants in Portland Farmer’s markets Whole Foods, Natural Grocers Local food Co-ops (First Alternative, LifeSource)  Nadine’s recommendations re: food options Organic produce Grass-fed meat Whole foods produced locally  The misguided reason why people do a gluten challenge Want to prove presence of celiac disease You don’t have to prove to anyone, especially if HLA-DQ2 or HLA-DQ8 gene carrier 30-50% of population has genetic predisposition to celiac disease  The value of a gluten-free diet in preventative medicine Averts celiac disease and associated issues Prevents other autoimmune disorders Type 1 diabetes Lupus Sjögren’s Rheumatoid arthritis MS ALS  What it means to do a gluten challenge Targets patients who have adopted a gluten-free diet Requires they consume gluten (2-6 slices of bread/day)  The consequences of a gluten challenge on celiac and gluten sensitive patients Seizures GI bleeds Appearance of bowel cancer, bone cancer Inability to get out of bed Organ damage  The risks vs. rewards of enduring a gluten challenge No benefit other than proving presence of celiac disease Can be thrown into refractory celiac disease (permanent, irreversible damage to intestines)  Why Nadine would never do a gluten challenge  Why biopsy results are no longer considered the gold standard of celiac testing Often misinterpreted, read incorrectly Damage can be patchy  Why an antibody panel can be unreliable in identifying celiac disease Takes time for body to mount autoimmune response 70% false negative nationwide  How long it takes to obtain celiac diagnosis Two to three weeks in countries where medical community is savvy about celiac disease Nine to 15 years in US  Nadine’s advice around celiac testing Seek practitioner with experience reading results Request total IgA, IgG Consider Cyrex Laboratories, LabCorp or EnteroLab  The enduring nature of celiac disease Doesn’t go away Children don’t grow out of it  Nadine’s nutrition guidelines for celiac patients Gluten- and dairy-free Ideally Paleo Nutrient dense foods  Nadine’s work as a patient advocate Seeks to help people stay healthy, avoid illness/disease Patients get lives back, active and thriving Resources: Whole Foods Natural Grocers First Alternative Co-op LifeSource Co-op Cyrex Laboratories LabCorp EnteroLab Connect with Nadine:  Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Melodies of the Danube Gluten-Free Cruise with Nadine Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

Celiac disease is grossly underdiagnosed in the United States in large part because the medical community is operating on outdated information about the condition. And despite the recommendations of the National Institute of Health back in 2004, we have yet to implement a mass screening for celiac disease, and health care providers remain alarmingly uninformed. The Gluten Free RN is taking steps to remedy the situation by sharing the basics for medical professionals. Today she covers the WHO’s definition of celiac disease, how our understanding of the condition has change over time, and some common misconceptions about celiac disease. She also explains the top symptoms, recommended testing for celiac disease and gluten sensitivity, and the neurological nature of the disorder. Listen in to learn what health care providers need to know about this undiagnosed epidemic, the complex web of health issues that may result from undiagnosed celiac disease, and why it is important to have a high index of suspicion and include celiac testing on every differential diagnosis. Help your patients go gluten-free and collect something other than autoimmune disorders!  What’s Discussed:  The standard of care in the US Providers should have diagnosed at least 1% of patients with celiac disease Undiagnosed for 70 years, must overcome to prevent further pain and suffering The goals of Nadine’s consulting business Works with facilities to protect celiac patients Ensure compliance with ADA How the media portrays the gluten-free lifestyle Dissuades people from adopting diet (program sponsors influence messaging) Negative headlines How our understanding of celiac disease has changed over time The recommendations of the 2004 NIH consensus meeting regarding celiac disease Mass screening (meets WHO criteria) Education for health care providers The World Health Organization criteria for mass screening Early clinical detection essential Condition is common Screening tests highly sensitive and specific Effective treatment available Untreated condition leads to complications The autoimmune disorders associated with undiagnosed celiac disease MS Type 1 diabetes Lupus Rheumatoid arthritis Sjögren’s Vitiligo The WHO definition of celiac disease Characterized by hypersensitivity to gluten Prevalence currently estimated at 1:1,000 worldwide Screening trials suggest prevalence of 1:100 Results in weight loss, diarrhea, nutritional deficiencies Caused by villous atrophy May present as extraintestinal manifestations or remain clinically silent Why celiac disease can’t be ruled out with a single test Can be triggered at any point HLA-DQ2 and HLA-DQ8 genes indicate genetic predisposition Misconceptions about celiac disease in the US medical community Thought to be digestive disorder, but really neurological Can present with seizures, numbness, constipation, balance issues, celiac cerebellar ataxia How skin issues are a reflection of what is going on internally Epithelial skin is same tissue as inside How damage to the small intestine leads to multiple health issues Increased permeability of intestinal wall Leaky blood brain barrier Leaky blood vessels Leaky lungs and skin The classic symptoms of celiac disease Chronic diarrhea Malabsorption Extreme weight loss Malnutrition What celiac disease looks like in children Diarrhea, constipation General abdominal pain Failure to thrive Falling off growth chart Short stature Learning disabilities ADD, ADHD, ODD Autism Skin issues (eczema, cirrhosis, acne) Delayed puberty Dental problems Anorexia, obesity Bed wetting The prevalence of celiac disease in older adults 30% of people diagnosed with celiac disease are over 60 Potential signs of celiac disease in the aging population Dementia Alzheimer’s Vision, hearing loss Urinary problems Cancer diagnosis (especially bowel cancer) Ataxia Arthritis Hair loss Fatigue Osteoporosis Anemia The elements that get into your blood stream as a result of villous atrophy Toxins Heavy metals Undigested food particles Yeast, fungus Parasites, other harmful bacteria Top symptoms of celiac disease Chronic anemia Fatigue Muscle, joint pain Depression, irritability Thyroid disorders Infertility issues GI problems (from mouth to rectum) Migraine headaches Psychiatric disorders Seizures Dermatitis herpetiformis Down, Turner or Williams syndrome Cardiomyopathy The effects of gluten on the brain Anger Depression, anxiety Learning disabilities Lethargy Insomnia Brain fog Schizophrenia Dyslexia Populations affected by celiac disease Any age, race, gender 3 million people all over the world Study of healthy blood donors in Mexico found unexpectedly high prevalence of tTGA positivity Now recognized as common disease among Middle Eastern and North African populations 1:7 Americans suffer from non-celiac gluten sensitivity (43 million people) The findings of an economic study by Columbia University Non-diarrheal presentations now most frequent Celiac disease grossly underdiagnosed in US Average delay in diagnosis is 4-11 years for adults in North America Significant improvement in quality of life when patients diagnosed and treated appropriately The importance of ensuring that medications are gluten-free Nadine’s recommendations around nutrition for celiac patients Gluten- and dairy-free Ideally Paleo Super-good high fat Things to consider re: the results of a celiac panel A positive test guarantees intestinal damage Include total IgA and IgG 70% produce a false negative Additional tests that offer valuable information Fecal fat score (ask for #, over 300 indicates malabsorption) Complete blood count Comprehensive metabolic panel Vitamin D3 level (below 40 ng/ml is critically low) Vitamins A, E & K levels Vitamin B6 & B12 levels MTHFR gene test Magnesium RBC test Zinc level Iodine level B9/Folate level Ferritin level Iron level Thyroid panel Bone density test Lipid panel ANA test (autoimmune issues) ESR test CRP test Surprising facts around celiac disease contrary to conventional wisdom Only 15% of celiac patients have chronic diarrhea 39% of celiac patients are overweight Shampoos, cosmetics and airborne gluten affect patients with gluten intolerance and celiac disease Super-good high fat diet is essential for celiac patients   Resources: NIH Consensus Statement “Where Have All the American Celiacs Gone?” in Acta Pediatrica Montana Gluten Free “Economic Benefits of Increased Diagnosis of Celiac Disease in a National Managed Care Population in the United States” in the Journal of Insurance Medicine “Celiac Disease Could be a Frequent Disease in Mexico: Prevalence of Tissue Transglutaminase Antibody in Healthy Blood Donors” in the Journal of Clinical Gastroenterology “Celiac Disease in Middle Eastern and North African Countries: A New Burden? in the World Journal of Gastroenterology Recommended Labs CDC 2013 Report Antibiotic Resistance Threats Cyrex Laboratories LabCorps Glutenpro EnteroLab Primal Docs Connect with Nadine:  Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Melodies of the Danube Gluten-Free Cruise with Nadine Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism  

Did you know that the spleen plays a leading role in a properly functioning immune system? As the largest organ in your lymphatic system, the spleen spends its time fighting infection and keeping you healthy. Unfortunately, research points to a connection between disorders of the spleen and celiac disease. And if your immune system is already compromised because of gluten damage to your intestines, a spleen issue leaves you at heightened risk for a variety of infections and autoimmune diseases. Today the Gluten Free RN shares her personal connection to genetic spherocytosis and how spleen damage affected her family. She also covers several studies that document the correlation between spleen issues and celiac disease. Listen in to understand how your spleen functions, the symptoms of spleen disorder, and the autoimmune diseases you may develop if your spleen is damaged or removed. What’s Discussed: How your spleen works to keep you healthy Filters used/damaged red blood cells Harvests iron to recycle Produces antibodies, white blood cells Fights infection Vital to immune system Conditions you may acquire if spleen is damaged (increased risk) Pneumonia UTI Overwhelming sepsis Instances in which spleen may be enlarged Mononucleosis Some bacterial infections, metabolic disorders Liver diseases Some blood cancers, lymphoma Blood clots in veins of liver, spleen Symptoms of spleen issues Pain in upper left quadrant Fatigue Anemia Bruise easily Bloated The correlation between genetic spherocytosis and celiac disease As high as 88% in some studies How the ratio of spleen diameter to RDW can indicate celiac disease Two-thirds of celiac patients in study had elevated red blood cell distribution width Small spleen in 80% of celiac patients Spleen diameter to RDW ratio under 6 had 88.5% specificity in predicting celiac disease Why patients with hyposplenism should get tested for celiac disease 25-75% of celiac patients have hyposplenism Look for red blood cell abnormality HLA-DQ2 and HLA-DQ8 genes indicate predisposition for celiac disease Antibody test available from EnteroLab or Cyrex Laboratories Ask for total IgA, IgG Other autoimmune diseases patients with hyposplenism may develop (increased risk) Type 1 diabetes Lupus Sjögren’s syndrome Vitiligo Raynaud’s Autoimmune thyroiditis ALS, MS, any demyelination of nervous system Idiopathic thrombocytopenia Autoimmune hepatitis Nadine’s recommendations around nutrition Local, organic Nutrient dense Gluten-free, Paleo The link between hyposplenism and autoimmune manifestations of celiac disease Autoimmune disorders may cause splenic hypofunction or vice versa Study hypothesizes that higher risk for splenic function in celiac patients may be related to celiac disease rather than autoimmunity Prevalence of celiac disease-associated hyposplenism increased from 19% in uncomplicated patients to 59% in those with autoimmune disorders Why celiac patients may not benefit from iron supplements, infusions Damaged intestines cannot absorb iron Damaged spleen destroys healthy red blood cells  Resources: “Ratio of Spleen Diameter to Red Blood Cell Distributions Width” in Medicine (Baltimore) EnteroLab Cyrex Laboratories “Is it Worth Investigating Splenic Function in Patients with Celiac Disease?” in the World Journal of Gastroenterology “Hyposplenism in Gastrointestinal Disease” in Gut BMJ “Hyposplenism, Adult Coeliac Disease, and Autoimmunity” in Gut BMJ “Splenic Volume Differentiates Complicated and Non-Complicated Celiac Disease” in UEG Journal Connect with Nadine:  Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Melodies of the Danube Gluten-Free Cruise with Nadine Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

Struggling to maintain control of your blood sugar? A gluten-free diet may be the answer! If you have one autoimmune disorder, you have a 30-50% greater risk of developing another, and both type 1 diabetes and celiac disease fall into that category. As more and more research points to an enormous overlap between type 1 diabetes and celiac disease, it is in our best interests to mitigate additional risk by getting screened and/or adopting a gluten-free or Paleo diet to mitigate further risk. Today Nadine discusses the prevalence of diabetes, several research studies that explore the connection between type 1 diabetes and celiac disease, and the potential risks for type 1 diabetics who are undiagnosed celiac patients. Listen and learn how your diet may be affecting your blood sugar and why going gluten-free could improve your health and quality of life! What’s Discussed:  The prevalence of diabetes By 2050, half the population will have diabetes According to CDC, 29.1 million have diabetes One out of four don’t know they are diabetic 18,000 young people diagnosed from 2008-2009 The difference between type 1 and type 2 diabetes Minimize risk for type 2 through diet and exercise Type 1 is autoimmune disorder, don’t produce enough insulin to break down sugar Symptoms of type 1 diabetes Extreme thirst Urgency to urinate frequently Fatigue Weakness The enormous genetic overlap between type 1 diabetes and celiac disease Scottish study found 94% of type 1 diabetics were HLA-DQ2 or HLA-DQ8 gene carriers 100% overlap if include HLA-DQ2.2 Prevalence of celiac disease among type 1 diabetics is 20% higher than general population The importance of testing all type 1 diabetics for celiac disease annually Can develop celiac disease at any age The consequences of undiagnosed celiac disease in children with type 1 diabetes Short stature Failure to thrive Early onset osteopenia, osteoporosis Easily broken or rubbery bones Difficulty maintaining glycemic control (low blood sugar, spikes) Anemia The decreased quality of life for type 1 diabetics who are undiagnosed celiac Development of infections Difficulty with blood sugar maintenance Research studies re: the percentages of type 1 diabetics who also have celiac disease Iraq – 11.2% Mexican participants – 5.9% Denmark – 12.3% Nadine’s anecdotal evidence of the overlap Volunteers at community outreach clinic Young man struggling to control blood sugar Nadine recommended gluten-free diet Improved health and quality of life Health risks associated with an inability to control blood sugar Blindness Kidney failure Amputation of extremities Difficulty healing wounds Heart attacks Strokes Why carb counting doesn’t control blood sugar Carbs with little/no nutrient value cause spikes in blood sugar The diet Nadine recommends for type 1 diabetics Variation of Paleo diet Nutrient dense foods Meat and fish Eggs Fruits and vegetables Nuts and seeds The benefits of a gluten-free diet for type 1 diabetics Weight easier to control Immune system works better Tighter control on blood sugar The lack of uniformity in screening guidelines Additional autoimmune diseases that may be avoided with a gluten-free diet Multiple sclerosis Lupus Sjögren’s Scleroderma Autoimmune thyroiditis Graves’ disease Hashimoto’s Vitiligo Raynaud’s Potential triggers for autoimmune disorders Gluten Change in microbiome Stress to body (i.e.: cold, food poisoning, travel)  Treatments for small intestinal bacterial overgrowth Low FODMAPs or specific carb diet Rifaximin (antibiotic) The dangers of maintaining high blood sugar Damage to kidneys, eyes, capillaries, fingers and toes Neuropathy Gastroparesis The long history of a connection between type 1 diabetes and celiac disease The need for information re: the connection in diabetic education services Resources: “Type 1 Diabetes and Celiac Disease: The Effects of Gluten Free Diet on Metabolic Control” in the World Journal of Diabetes “Co-occurrence of Type 1 Diabetes Mellitus and Celiac Disease” in the World Journal of Diabetes “Screening for Coeliac Disease in Adult Patients with Type 1 Diabetes Mellitus: Myths, Facts and Controversy in Diabetology & Metabolic Syndrome “The Prevalence of Coeliac Disease in Libyan Children with Type 1 Diabetes Mellitus” in Diabetes Metabolism Research and Reviews “Type 1 and Type 2 Diabetes in Celiac Disease: Prevalence and Effect on Clinical and Histological Presentation” in BMC Gastroenterology “Coexistence of Coeliac Disease and Type 1 Diabetes” in Przeglad Gastroenterologiczny “Screening for Celiac Disease in Type 1 Diabetes: A Systematic Review” in AAP News and Journals Connect with Nadine:  Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

‘With our technology, every time a woman dies, it’s a medical error.’  Recent reports have uncovered some alarming statistics regarding maternal mortality rates in the United States. While these numbers are on the decline in every other developed nation, pregnant women in the US are at greater risk of dying than they were in recent years. We know that undiagnosed celiac disease has a significant impact on maternal health and fetal development, and we must identify expectant mothers (and fathers) who have the potential to reap remarkable benefits from a simple diet change. This issue is especially important to the Gluten Free RN as a mother herself – as well as an emergency ER nurse certified in PALS, NLS and pediatric emergency nursing. She shares the stories of women who had difficulty getting pregnant or maintaining pregnancies as a result of undiagnosed celiac disease and gluten sensitivity, and explains how a mass screening could work to prevent such intense suffering. Listen to learn how adopting a gluten-free or Paleo diet can help women carry their babies to full-term and deliver healthy, thriving children! What’s Discussed:  Nadine’s mission to get women tested for celiac disease prior to pregnancy Allows to absorb nutrients during pregnancy (including prenatal vitamins) Can deliver healthy, thriving child  The story of Alice Bast Suffered miscarriage and still births Multiple doctors couldn’t provide answers Vet gave idea to test for celiac disease Founded the National Foundation for Celiac Awareness  The necessity for a mass screening of men and women Identify HLA-DQ2 and HLA-DQ8 gene carriers Genes of both parents affect fetal health Ratio of women to men with celiac disease is 1:1 Ratio of women to men diagnosed with celiac disease is 3:1  The increased risks for pregnant women with undiagnosed celiac disease Miscarriage Still birth Low birth weight Failure to thrive in children Pre-eclampsia/eclampsia (dangerously high blood pressure)  The role men play in infertility ED, low sperm count and low libido may be attributed to undiagnosed celiac disease Symptoms include deficiencies in zinc, magnesium and B vitamins as well as anemia and osteoporosis  The argument that a mass screening for celiac disease is too expensive The cost associated with undiagnosed celiac disease is much higher Consists of medical costs from complications Also includes decreased productivity and morbidity/mortality Study published in Science Digest found that 42,000 children may die annually due to undiagnosed celiac disease  Conditions that indicate high risk for celiac disease Chronic GI issues Irritable bowel syndrome Weight loss/gain Iron deficiency anemia Vitamin/mineral deficiencies Secondary hyperparathyroidism Unexplained elevations in liver function Down, Turner or Williams syndrome Type 1 diabetes Lupus Autoimmune thyroid disease  Sam’s story Delayed puberty (didn’t get period until 17-years-old) Diagnosed with celiac disease at 19 Doctors warned she would probably never have children Raising two healthy boys  Why Nadine is concerned about the current generation of children Higher rates of autoimmune diseases, cancer and learning disabilities  The appropriate diet to promote maternal health and proper fetal development Gluten- and dairy-free Paleo is best Humans have enzymes to break down meat proteins Humans do not have enzymes to break down grain proteins Avoid wheat, barley, rye and oats Embrace meat, fish, eggs, fruits, vegetables, nuts and seeds  Deficiencies that can be corrected to promote healthy pregnancy B6 and B12 A, D, E and K (the fat-soluble vitamins) Magnesium RBC Zinc  The US maternal mortality rate compared to other developed nations Rising in the US, declining in other developed nations 28 deaths for every 100,000 births in 2013, up from 23 in 2005 Resources: “Maternal Mortality Rate in US Rises, Defying Global Trend, Study Finds” in The New York Times “Focus on Infants During Childbirth Leaves US Moms in Danger” on NPR Beyond Celiac: Alice Bast “Reproductive Changes Associated with Celiac Disease” from the World Journal of Gastroenterology “Celiac Disease and Reproductive Health” from Celiac Disease: A Comprehensive Review and Update Connect with Nadine:  Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

In Italy, it takes only two to three weeks to get diagnosed with celiac disease. In the United States, however, it typically takes nine to 15 years. Why is there such a huge discrepancy? And what are the legal ramifications for practitioners who overlook celiac disease and non-celiac gluten sensitivity, causing patients unnecessary pain and suffering?  On this episode, Nadine explores the legal issues surrounding celiac disease as well as the potential reasons for delayed diagnosis in the US. She also explains the differences between universal healthcare and the for-profit system and how each appears to influence celiac diagnosis.  Listen and learn what medical practitioners need to know about celiac disease and gluten sensitivity in order to avoid being sued for malpractice, the value of standardization in celiac testing and follow-up care, and how you can get involved in advocating for universal coverage. What’s Discussed:  How the US health insurance system works Usually purchased through employer Loss of job often means loss of coverage ACA provides coverage for many who were uninsured For-profit system  Why Nadine is an advocate for a single-payer system People treated in ER with or without insurance (we pay regardless) US healthcare is very expensive, yet outcomes poor  Celiac disease diagnoses around the world Italy: 2-3 weeks; standardized follow-up care US: 9-15 years; patients endure numerous other tests, misdiagnoses, unnecessary medications Canada: effective early diagnosis, but follow-up care lacking  The excuses practitioners use to avoid diagnosing celiac disease Don’t believe in it, despite research and documentation Don’t want to learn about another illness Gluten-free diet is too difficult for patients  Symptoms Nadine encountered as an ER nurse that may have signaled celiac disease Migraine headaches Abdominal pain Neurological disorders (headaches, difficulty with balance) Fever  Why practitioners should be concerned about malpractice suits if celiac disease goes undiagnosed Ignorance is not a defense Michael Marsh contends that failure to do appropriate screening signals liability Avoid by learning the basics of celiac disease, how to diagnose and follow-up  Why celiac disease needs to be part of differential diagnosis for every patient  Indicators of celiac disease and non-celiac gluten sensitivity HLA-DQ2 or HLA-DQ8 gene denotes predisposition for celiac proper AGA antibody suggests gluten sensitivity  Maladies suffered by patients whose celiac disease went undiagnosed Mental health issues Neurological disorders Seizures Balance issues Abdominal pain Incorrect diagnosis of Crohn’s or colitis Hemorrhoids GERD High blood pressure Heart attack Stroke Cancer  Why standardization of testing and follow-up care is a necessity Screenings are often misinterpreted Celiac patients who follow a gluten-free diet are often told that they have been cured or that the initial test was a false positive when follow-up shows antibodies in normal range  The story of Nadine’s 70-year-old celiac patient Diagnosed with celiac disease by biopsy, but received no follow-up care Suffered from significant neurological issues (e.g.: gluten ataxia, falling) Nadine recommended standard lab tests Primary care doctor refused Patient returned to Nadine in distress Doctor culpable for patient’s neurological damage  Why celiac patients should consider advocating for universal coverage  The differences between celiac diagnoses under universal vs. for-profit insurance systems Financial benefit to early diagnosis under universal system (i.e.: UK, Canada, Italy) No benefit to early diagnosis for insurers under for-profit structure Resources Mentioned:  Physicians for a National Health Program  Health Care for All Oregon  Mid-Valley Health Care Advocates Additional Resources:  “Economic Benefits of Increased Diagnosis of Celiac Disease in a National Managed Care Population in the United States” from the Journal of Insurance Medicine Connect with Nadine:  Instagram Facebook Contact via Email Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

Wherever there is wheat, there is susceptibility to celiac disease and non-celiac gluten sensitivity. Gluten is a growing global problem, exacerbated by the popularity of the western diet around the world. This issue has personal, social and political implications as it places a significant economic burden on individuals, communities, and even entire nations.  The Gluten Free RN brings us a ‘big picture’ perspective of the celiac and gluten sensitive population around the world, as we learn about how other countries support these individuals. She also covers the industries that have begun to recognize the power of the gluten free population as a consumer group.  Nadine will be doing some globe-trotting herself come September for the International Celiac Disease Symposium in New Delhi, and she is currently soliciting advice regarding where and how to eat safely during her travels in India and Thailand. Feel free to message her with recommendations!   What’s Discussed:  When and where wheat originated Fertile Crescent (Northern Africa and the Middle East) 10,000 years ago High prevalence of celiac disease in these regions now  The International Celiac Disease Symposium September 2017 in New Delhi Held every two years Scientists, medical professionals and other interested parties Share latest research  Where celiac disease is common Anywhere people are eating grains More widespread as other regions adopt a western diet Increased risk in Punjab population of India  The basics of celiac disease and non-celiac gluten sensitivity Can present in many ways (300+ signs and symptoms) #1 autoimmune disease in the world More likely to recover the sooner identified 30-50% of the population carry the genes (HLA-DQ2 and HLA-DQ8) that indicate predisposition Body doesn’t have enzymes to break down gluten proteins Gluten damages intestines Nadine recommends adopting a Paleo diet in order to heal  The World Health Organization’s “burden of disease” Measures the impact of celiac disease Based on financial cost, mortality, morbidity, etc.  How Italy supports celiac patients Provide extra days off work for doctor’s appointments, shopping Ship gluten free food  Potential symptoms of celiac disease affecting every ethnicity Odd gait (gluten ataxia) Skin rash (dermatitis herpetiformis)  The power of celiac and gluten-sensitive patients as a group Largest untapped market in the world Some industries taking notice (pharmaceutical, food) Use influence to heal selves and educate others  Why some people are so resistant to eliminating grains Sometimes crave what is bad for you Nutritional deficiencies may cause addiction  Resources Mentioned:  Guns, Germs, and Steel: The Fates of Human Societies -  by Jared M. Diamond Connect with Nadine:  Instagram Facebook Contact via Email Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism