Podcasts about Underlying

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  • 994PODCASTS
  • 1,227EPISODES
  • 39mAVG DURATION
  • 5WEEKLY NEW EPISODES
  • Jun 28, 2022LATEST

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Best podcasts about Underlying

Latest podcast episodes about Underlying

Hormonally Yours with The Hormone Dietitian

A Hormones and Mental Health Episode Why is it that so many women struggling with hormone imbalances also struggle with anxiety? Turns out that the root causes of anxiety overlap with the root causes of hormone imbalances... and having hormone imbalances can contribute to anxiety as well. From an integrative and functional perspective, anxiety is not a "diagnosis," per se... it's a SYMPTOM. And in order to identify the best approach to treating it, we have to uncover what the root causes of anxiety are on an individual basis. In this episode, I'm talking with Dr. Jen Roelands about the most common root causes of anxiety, the difference between anxiety and stress, and treatment options — which can include a variety of tools depending on your goals, including nutrition, lifestyle, supplements, and medications. Dr. Jennifer Roelands is an integrative medicine trained OB/GYN with over a decade of women's health experience. She is the CEO and founder of Well Woman MD, a clinic dedicated to a holistic, whole-body approach to care by using nutrition, lifestyle, and cutting-edge testing. She is also the host of Ignite Your PowHer podcast, a platform for badass female entrepreneurs in the health and wellness industry. Dr. Jen is an avid outdoor enthusiast and traveler. Most importantly she is the GO-TO math expert for her 4 energetic kids. This Week We Talk About:  Why choice matters when it comes to a treatment approach for hormone imbalances and anxiety — whether you want a strictly conventional approach, a strictly natural approach, or a combination of the two modalities The connection between hormone imbalances and anxiety, depression, and other mood disorders What's really underlying anxiety, and what anxiety is actually a symptom of Underlying root causes of inflammation and anxiety Why women are more prone to anxiety than men and times in the lifespan where anxiety is more common Symptoms of anxiety, types of anxiety, and how anxiety differs from day-to-day stress Managing anxiety around a chronic condition such as PCOS Labs to consider if you have anxiety Different treatment approaches to anxiety depending on your situation Nutrition and lifestyle tips for managing anxiety When you might want to consider medications for anxiety, alternatives to anxiety meds, and weaning off anxiety meds safely Mentioned in this episode PCOS Meal Prep Made Easy Workshop – In this hour-long workshop, I break down what foods you want to include for PCOS and what you may want to consider avoiding or minimizing. Learn my simple 3-step formula for planning meals with PCOS, which includes learning how to eat to balance blood sugar.   Where to find Dr. Jennifer Roelands: Dr. Jen's website: WellWomanMD.com Dr. Jen's Instagram: @wellwomanmd Download Dr. Jen's Freebie: Get Relief from Anxiety   Love the podcast? Leave a rating and review! Or share an episode with a friend who could benefit! Give us a follow on Instagram or Facebook for daily posts on PCOS, hormones, and fertility. Check out our website for more articles and information and to learn how to work with Melissa.

Fasting For Life
Ep. 131 - The Underlying Blood Sugar Related Effects of Walking | Free Intermittent Fasting Plan for OMAD

Fasting For Life

Play Episode Listen Later Jun 28, 2022 23:14


In this episode, Dr. Scott and Tommy discuss the underlying blood sugar-related effects of walking, and the importance of improving the post-meal glycemic response for reducing cardiometabolic disorders. Walking can be a powerful tool to reduce heart disease and insulin resistance!!   Show Transcript: www.thefastingforlife.com/blog   Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new and experienced fasters! The first two rules of fasting need not apply!   Fasting For Life Community - Join HERE   New to the podcast and wondering where to start? Head to the website and download our FREE Fast Start Guide, 6 simple steps to put One Meal a Day Fasting (OMAD) into practice!   Maybe you are an experienced faster and wondering about your results and IF they could be linked to INSULIN resistance? Head over to the website and download our FREE Insulin Resistance Assessment!   Or get both here at our website:  www.thefastingforlife.com/resources   If you enjoy the podcast, would you please tap on the stars below and consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it makes a difference in helping bring you the best original content each week. We also really enjoy reading them!   Sign up for the Fasting For Life newsletter at www.thefastingforlife.com   Follow Fasting For Life: www.facebook.com/thefastingforlife www.instagram.com/thefastingforlife Join the Community on Facebook!   Reference Links: https://pubmed.ncbi.nlm.nih.gov/35268055/  

piworld audio investor podcasts
Appreciate Group (APP) Full year 2022 results presentation - June 2022

piworld audio investor podcasts

Play Episode Listen Later Jun 28, 2022 32:54


Appreciate's CEO, Ian O'Doherty, CFO, Tim Clancy and COO, Julian Coghlan, present the full-year 2022 results for the year ended 31 March 2022. Ian O'Doherty, CEO 00:17 - Introduction 00:58 - Bounce back from Covid 01:59 - Platform of growth Tim Clancy, CFO 03:31 - Financial highlights 04:03 - Statuary P&L 05:40 - Underlying performance 06:34 - Historic EBITDA 07:38 - Billings and revenue 08:18 - Segmental performance 08:46 - Billings by format 09:13 - Park Christmas Savers 09:55 - Corporate 10:53 - Redemption levels 11:29 - Balance sheet 11:55 - Cash flow 12:51 - Financial summary Ian O'Doherty, CEO 13:31 - The growth strategy Julian Coghlan, COO 14:16 - Growth via market leading channels 16:27 - Appreciate Business services highlights 17:49 - Multiple growth initiatives 20:37 - Christmas savings: Business highlights 21:49 - Multiple growth initiatives 24:44 - Love2shop key customers 25:05 - Key enabler for growth Ian O'Doherty, CEO 27:22 - MBL Acquisition 30:10 - ESG update 31:28 - Summary Appreciate Group plc is a United Kingdom-based gifting and engagement company. The Company has a portfolio of brands, designed for the consumer and business customers. Its consumer-facing brands meet a range of saving and gifting needs, while its business products help its corporate customers reward and recognize their employees and clients. The Company's brands include Love2shop, highstreetvouchers.com, Park Christmas Savings and Appreciate Business Services. Its products include Love2shop Gift Card, Love2shop Gift Voucher, Love2shop Holidays, Single store vouchers and gift cards, Corporate gift cards and VIP experiences and group travel. Love2shop Gift Card is a flexible, pre-paid gift card that enables its customers to spend in their high street stores and a selected range of online retailers. The Love2shop Gift Voucher is a multi-retailer voucher, which can be used to buy products from approximately 200 brands and over 25,000 retail outlets.

Road to Seven
The Underlying Connector to Everything is Authenticity

Road to Seven

Play Episode Listen Later Jun 28, 2022 35:06


“If you cannot figure out what solution your business is solving, you need to go back to the drawing board.”- Tanya HaylesGet ready to be inspired… and take more than a couple of notes! Tanya Hayles is a multi-passionate entrepreneur who has created not one, but THREE businesses that are creating massive impact around the world! Tanya's thriving online global village and nonprofit, Black Moms Connection, provides financial support grants and culturally relevant resources to empower Black women. Her firm Color in White Spaces works to disrupt the diversity and inclusion world by making conversations about racism more real and relatable. And her storytelling and speaking talents have helped her to take the media world by storm!From developing her thought leadership to narrowing down on her key pillars, this fascinating conversation digs into Tanya's secret sauces for success — and her top tips for women looking to follow in her footsteps!In‌ ‌this‌ ‌episode of the Road to Seven podcast,‌ ‌you'll discover:‌ ‌Where and how Tanya shared her voice in order to attract inquiries from so many media outlets How Tanya has evolved her pricing structure over time — and why outlets are so eager to pay her!Why you want to be The Beer Store, rather than Walmart, in terms of how you niche downAbout Tanya Hayles: Tanya Hayles is an award-winning creative, authentically telling stories and creating change, building movements through the online global village of 30,000 Black Moms Connection, and making DEI work real and relatable through her firm Color In White Spaces.  Highlights:‌ ‌00:01  Intro03:04  Meet Tanya Hayles06:42  Pandemic pivot & pitching09:56  Sharing her voice online12:59  Be The Beer Store, not Walmart15:55  Choose your lane & trust the universe18:30  Money talk21:40  Black Moms Connection28:47  What she knows now ‌Links:‌ ‌Tanya Hayleshttps://www.tanyahayles.com https://www.blackmomsconnection.com https://www.facebook.com/blackmomsconnection https://colorinwhitespaces.com https://www.linkedin.com/in/thayles Twitter: @tanyahayles Instagram: @thetanyahayles, @blackmomsconnection   To work with me and make your next power move, visit:https://shelaghcummins.com    ‌Stay Connected  Like what you're hearing? Click here to subscribe in iTunes for more episodes with great tips and conversations with women that are revolutionizing the way we do business - don't miss it!   You can also join the Road To Seven Facebook group to meet other like-minded entrepreneurs who want to band together and help each other rise up.  Join the road to seven FB group here: https://www.facebook.com/groups/867037907397297

Pipettes and Politics
Greg Wang | Chromatin-based modulations underlying gene regulation and pathogenesis

Pipettes and Politics

Play Episode Listen Later Jun 27, 2022 28:51


Greg Wang, winner of the 2022 ASBMB Young Investigator Award, presented his lecture, "Chromatin-based modulations underlying gene regulation and pathogenesis," at the 2022 ASBMB Annual Meeting in Philadelphia. Learn more about his work: https://www.asbmb.org/asbmb-today/people/121621/wang-s-studies-are-fueled-by-interest-in-cells. On August 9, 2022 he will also be presenting this talk as a webinar. Register here to join and participate in a Q&A session: https://www.asbmb.org/meetings-events/chromatin-based-modulations.

Transforming Work with Sophie Wade
46: Dom Price — Tackling Underlying Issues: Straight Forward, but Not Simple Solutions

Transforming Work with Sophie Wade

Play Episode Listen Later Jun 24, 2022 61:24


Dominic Price, Work Futurist at Atlassian, first explains unlearning. He discusses the excitement and challenges of his work ensuring his company keeps adapting to stay ahead of competitors as it grows rapidly year on year. Focused on anticipating, exploring, and improving ways of working, Dom offers suggestions to specific questions that we are all currently trying to answer such as about hybrid work models, burnout, transformation challenges, and more, sharing his lived experiences, experiments and refined solutions.   KEY TAKEAWAYS   [03:10] Starting as a chartered accountant, Dom found a “job for life” wasn't his vocation.   [03:54] Not wanting to fit into a box, Dom had to accept uncertainty and unlearn structure.   [05:34] How to be happy with career progress when “learning” is the key measurement.   [07:47] When Dom joined Atlassian it was one of the “best places to work”, but he hated it.   [08:31] Applying his skills very differently, Dom was confronted reframing his “firefighting” role.   [11:58] Dom's boss challenges him to adapt and grow 40% each year to stay in his current role.   [14:10] We go back to old thinking because it was certain, not because it was valuable.   [15:22] Dom's fascination with technology ends up with him focused on people.   [17:48] Question 1 – How to tackle the complexity of hybrid models?   [19:24] Underlying question – How do we become place agnostic?   [20:24] When we are place agnostic, how can we find effective ways of working?   [22:18] Question 2 – How does work “work” now?   [23;15] Underlying question – What more can we understand about what it is to be human?   [21:45] You can offer flexibility to your on-site workers. Dom explains how.   [24:23] The importance of psychological safety.   [26:14] Dom experiments and gives an asynchronous workshop.   [28:12] We have to experiment and explore our way forward in the Future of Work.   [29:11] Question 3 – How do you learn a growth mindset?   [30:14] Dom's Five Ls exercise that he practices regularly.   [32:55] The importance of role modeling behavior as leaders now.   [36:03] Question 4 – How to embrace change and stop people resisting change?   [37:50] Breaking down transformation into “what's one thing we can do today?”   [39:40] Celebrating “the good old days” in a positive way to be able to move forward.   [42:41] Question 5 – How to get rid of so many meetings?   [46:19] Questions 6 - How do we reduce burnout?   [47:15] Question 7 – Should I leave my employer?   [48:55] Be the change you seek. Feedback is a gift, but only if you give it!   [51:28] Question 8 & 9 – How can you help employees think through how to live their lives differently? How can their boss support this process?   [52:00] Why Dom thinks we are obsessed with perfection and we should focus on progress.   [52:45] Systems thinking—we can block progress if we only see the boundaries of the system.   [53:51] Learning organizations don't exist, but learning loops do.   [55:42] Dom believes the organization chart is damaging—hindering progress in organizations.   [57:33] Leadership is based on competence, not level.   [59:37] IMMEDIATE ACTION TIP: If you've been taking mental or written notes listening to this episode, don't sign up for more knowledge obesity, find ONE thing you are willing to try, and put a date on it.     RESOURCES   Dom Price on LinkedIn Dom Price on Twitter Domprice.me Atlassian.com Atlassian's Team Playbook   QUOTES   “I need to unlearn all these things I got taught early on in my career, about “you must have a career plan”.”   “If you wanna be great, you're gonna have to evolve how you work, how your teams work, how you influence. You're gonna have to adapt to everything constantly.”   “How do we get those teams in a distributed fashion to work effectively together? Once we solve that everything else is done, right? Everything else is gravy.”   “How can we work human to human? How do we amplify that with technology? Technology isn't the answer, it's the amplifier.”   “How do I build a balanced life and where does work fit into that?”   “If you've got an hour, spend five minutes reminiscing on the good old days, spend the other 55 building better days tomorrow.”   “Leadership is based on competence, not level.”  

MONEY FM 89.3 - The Breakfast Huddle with Elliott Danker, Manisha Tank and Finance Presenter Ryan Huang
Why It Matters: Overview of the agri-food business in SEA, its underlying challenges

MONEY FM 89.3 - The Breakfast Huddle with Elliott Danker, Manisha Tank and Finance Presenter Ryan Huang

Play Episode Listen Later Jun 24, 2022 13:23


The GrowHub together with the FIPWA is looking at contributing to a ‘food bowl' for consumers in Southeast Asia as well as contributing to addressing Singapore's ‘30 by 30' food security goal.  Christopher Vas, Country Manager Australia, The Growhub & General Manager, FIPWA gives us an overview of the agri-food business in the region and its current food security situation.  See omnystudio.com/listener for privacy information.

Epigenetics Podcast
Epigenetic Clocks and Biomarkers of Ageing (Morgan Levine)

Epigenetics Podcast

Play Episode Listen Later Jun 23, 2022 33:40


 In this episode of the Epigenetics Podcast, we caught up with Morgan Levine from Altos lab to talk about her work on Epigenetic Clocks and Biomarkers of Ageing. The Levine Lab focuses on deciphering mechanisms that lead to epigenetic ageing, which can be measured by epigenetic clocks. Epigenetic clocks were first described in 2011 by Bocklandt et al.. Later-on, the Horvath and the Hannum clock were described by using a combination of CpGs to calculate biological/epigenetic age in contrast to chronological age. The Levine Lab themselves worked on generating an advanced version of an Epigenetic clock, called "DNAm PhenoAge" that will now be used, and not only in human samples. The team now moves to mouse models and to cells in a dish and using those models to investigate the mechanisms behind epigenetic aging.   References Liu, Z., Leung, D., Thrush, K., Zhao, W., Ratliff, S., Tanaka, T., Schmitz, L. L., Smith, J. A., Ferrucci, L., & Levine, M. E. (2020). Underlying features of epigenetic aging clocks in vivo and in vitro. Aging cell, 19(10), e13229. https://doi.org/10.1111/acel.13229 Levine, M. E., Lu, A. T., Quach, A., Chen, B. H., Assimes, T. L., Bandinelli, S., Hou, L., Baccarelli, A. A., Stewart, J. D., Li, Y., Whitsel, E. A., Wilson, J. G., Reiner, A. P., Aviv, A., Lohman, K., Liu, Y., Ferrucci, L., & Horvath, S. (2018). An epigenetic biomarker of aging for lifespan and healthspan. Aging, 10(4), 573–591. https://doi.org/10.18632/aging.101414 Levine, M., McDevitt, R. A., Meer, M., Perdue, K., Di Francesco, A., Meade, T., Farrell, C., Thrush, K., Wang, M., Dunn, C., Pellegrini, M., de Cabo, R., & Ferrucci, L. (2020). A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin. eLife, 9, e59201. https://doi.org/10.7554/eLife.59201 Kuo, C. L., Pilling, L. C., Atkins, J. C., Masoli, J., Delgado, J., Tignanelli, C., Kuchel, G., Melzer, D., Beckman, K. B., & Levine, M. (2020). COVID-19 severity is predicted by earlier evidence of accelerated aging. medRxiv : the preprint server for health sciences, 2020.07.10.20147777. https://doi.org/10.1101/2020.07.10.20147777   Related Episodes Aging and Epigenetics (Peter Tessarz) Epigenetic Mechanisms of Aging and Longevity (Shelley Berger)   Contact Active Motif on Twitter Epigenetics Podcast on Twitter Active Motif on LinkedIn Active Motif on Facebook Email: podcast@activemotif.com

You Are Nourished
[3/4] Underlying “non-food” reasons for weight gain – Inflammation. With Emily Niswanger.

You Are Nourished

Play Episode Listen Later Jun 21, 2022 57:35


We're continuing our four-part series on reasons why you might be struggling to lose weight, by looking at inflammation. And this week I am joined by my first-ever podcast guest expert! Emily Niswanger, a Functional Dietitian from Anywhere Nutrition – who is an expert in all things to do with inflammation – joins me all the way from Minnesota! Now, when we think of inflammation, we tend to think of conditions where you can obviously see or feel the inflammation, like arthritis, for example, where you would experience persistent pain. Many of us don't realise that we can also have internal inflammation that goes on inside our bodies that we just don't see. Do you suffer from digestive issues like bloating? Do you lack energy all the time? Do you find it hard to concentrate and forget things a lot? These are all indicators of chronic inflammation! In this episode, Emily helps us delve into what inflammation is, why it can make weight loss difficult, and shares lots of ideas on changes you can make to your diet and lifestyle to reduce inflammation. “If you are struggling with inflammation in the body, no amount of dieting or exercise is going to help unless we deal with this root cause first.”  - Lauren Gayfer    In This Episode: Learn about different types of inflammation and how inflammation can prevent you from losing weight. Discover the role nutrition plays in exacerbating inflammation and how to look out for hidden ingredients in shop-bought products. Understand the importance of finding a healthy and sustainable balance with what you eat and how letting go of perfectionism will help reduce both stress and inflammation. Learn how different lifestyle factors can increase inflammation including some surprising things you think would have the opposite effect. Get top tips on healthier habits you can try to help reduce inflammation.    Resources mentioned: Connect with Emily on social media using @anywherenutrition or go to her website: http://www.anywherenutrition.com (www.anywherenutrition.com)  Find out more about the history of low-fat diets in podcast episode, ‘How to stop fearing full-fat foods', here: https://youarenourished.com/episode20 (https://youarenourished.com/episode20). Listen to the first episode in this series, ‘3 Underlying Reasons You Might Be Struggling to Lose Weight', here: https://youarenourished.com/episode21 (https://youarenourished.com/episode21). Listen to the second episode in this series, ‘Underlying “non-food” reasons for weight gain – Stress', here: https://youarenourished.com/episode22 (https://youarenourished.com/episode22). Connect with Lauren:  Instagram: https://www.instagram.com/nourished.lauren (https://www.instagram.com/nourished.lauren) Facebook: https://www.facebook.com/nourished.lauren (https://www.facebook.com/nourished.lauren) 

Bodybuilding and Physique Podcast
The Ultimate Guide To Weak Point Training

Bodybuilding and Physique Podcast

Play Episode Listen Later Jun 21, 2022 33:21


Work with me: https://docs.google.com/forms/d/15_F8... ———————————— 00:00 Introduction 00:39 Pre-emptive summary 01:56 The first set of problems: Minimalistic training 05:24 "PowerBuilding" 07:28 Strength focused bodybuilders 10:38 Summary so far 11:10 Execution: Intent and form 15:55 Summary of initial reasons for weakpoints under your control 16:22 Initial solutions 23:42 Summary of solutions to factors under your control 24:54 Underlying structural weaknesses 27:34 Poor Mind Muscle Connection 30:05 Secondary solutions to bridge genetic weaknesses 31:47 Summary & concluding thoughts ———————————— Support me on Patreon: https://www.patreon.com/fazlifts—————... Follow Me On ———————————— FACEBOOK: https://www.facebook.com/Fazlifts INSTAGRAM: https://www.instagram.com/fazlifts/ IGTV: https://www.instagram.com/fazlifts/ch... TWITTER: https://twitter.com/fazlifts ———————————— Subscribe To The Fazlifts Podcast ———————————— YOUTUBE: https://www.youtube.com/channel/UCPcc... ITUNES: https://podcasts.apple.com/gb/podcast... SOUNDCLOUD: https://soundcloud.com/fazlifts SPOTIFY: https://open.spotify.com/show/32tKW50... STITCHER: https://www.stitcher.com/show/bodybui... ———————————— WEBSITE: www.fazlifts.com ———————————— #teamfaz #hypertrophy #fullbody #fbr #musclegrowth #diet #fatloss #teamfaz #bulk #muscle #stronglifts #5x5 #531 #wendler #GVT #greyskull5x5 #fazlifts ————————————

PeerView Family Medicine & General Practice CME/CNE/CPE Audio Podcast
April W. Armstrong, MD, MPH / Kenneth B. Gordon, MD - Fine-Tuning the JAK/STAT Pathway in Psoriasis: Safely Targeting the Underlying Mechanisms of Disease With TYK2 Inhibition

PeerView Family Medicine & General Practice CME/CNE/CPE Audio Podcast

Play Episode Listen Later Jun 14, 2022 61:45


Go online to PeerView.com/CCT860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in dermatology discuss the role of the JAK/STAT pathway in psoriasis, as well as treatment with novel kinase inhibitors for the management of patients with psoriasis. Upon completion of this activity, participants should be better able to: Describe and differentiate targeting of the TYK2, JAK1, JAK2, and JAK3 kinases and the correlation to emerging therapies for the treatment of moderate to severe psoriasis, Summarize recent efficacy and safety data for current and emerging therapies for the treatment of moderate to severe psoriasis, Recommend treatment for patients with moderate to severe psoriasis according to the latest guidelines and clinical evidence, particularly as emerging therapies become available.

PeerView Clinical Pharmacology CME/CNE/CPE Video
April W. Armstrong, MD, MPH / Kenneth B. Gordon, MD - Fine-Tuning the JAK/STAT Pathway in Psoriasis: Safely Targeting the Underlying Mechanisms of Disease With TYK2 Inhibition

PeerView Clinical Pharmacology CME/CNE/CPE Video

Play Episode Listen Later Jun 14, 2022 62:10


Go online to PeerView.com/CCT860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in dermatology discuss the role of the JAK/STAT pathway in psoriasis, as well as treatment with novel kinase inhibitors for the management of patients with psoriasis. Upon completion of this activity, participants should be better able to: Describe and differentiate targeting of the TYK2, JAK1, JAK2, and JAK3 kinases and the correlation to emerging therapies for the treatment of moderate to severe psoriasis, Summarize recent efficacy and safety data for current and emerging therapies for the treatment of moderate to severe psoriasis, Recommend treatment for patients with moderate to severe psoriasis according to the latest guidelines and clinical evidence, particularly as emerging therapies become available.

PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast
April W. Armstrong, MD, MPH / Kenneth B. Gordon, MD - Fine-Tuning the JAK/STAT Pathway in Psoriasis: Safely Targeting the Underlying Mechanisms of Disease With TYK2 Inhibition

PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast

Play Episode Listen Later Jun 14, 2022 62:10


Go online to PeerView.com/CCT860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in dermatology discuss the role of the JAK/STAT pathway in psoriasis, as well as treatment with novel kinase inhibitors for the management of patients with psoriasis. Upon completion of this activity, participants should be better able to: Describe and differentiate targeting of the TYK2, JAK1, JAK2, and JAK3 kinases and the correlation to emerging therapies for the treatment of moderate to severe psoriasis, Summarize recent efficacy and safety data for current and emerging therapies for the treatment of moderate to severe psoriasis, Recommend treatment for patients with moderate to severe psoriasis according to the latest guidelines and clinical evidence, particularly as emerging therapies become available.

PeerView Internal Medicine CME/CNE/CPE Audio Podcast
April W. Armstrong, MD, MPH / Kenneth B. Gordon, MD - Fine-Tuning the JAK/STAT Pathway in Psoriasis: Safely Targeting the Underlying Mechanisms of Disease With TYK2 Inhibition

PeerView Internal Medicine CME/CNE/CPE Audio Podcast

Play Episode Listen Later Jun 14, 2022 61:45


Go online to PeerView.com/CCT860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in dermatology discuss the role of the JAK/STAT pathway in psoriasis, as well as treatment with novel kinase inhibitors for the management of patients with psoriasis. Upon completion of this activity, participants should be better able to: Describe and differentiate targeting of the TYK2, JAK1, JAK2, and JAK3 kinases and the correlation to emerging therapies for the treatment of moderate to severe psoriasis, Summarize recent efficacy and safety data for current and emerging therapies for the treatment of moderate to severe psoriasis, Recommend treatment for patients with moderate to severe psoriasis according to the latest guidelines and clinical evidence, particularly as emerging therapies become available.

PeerView Internal Medicine CME/CNE/CPE Video Podcast
April W. Armstrong, MD, MPH / Kenneth B. Gordon, MD - Fine-Tuning the JAK/STAT Pathway in Psoriasis: Safely Targeting the Underlying Mechanisms of Disease With TYK2 Inhibition

PeerView Internal Medicine CME/CNE/CPE Video Podcast

Play Episode Listen Later Jun 14, 2022 62:10


Go online to PeerView.com/CCT860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in dermatology discuss the role of the JAK/STAT pathway in psoriasis, as well as treatment with novel kinase inhibitors for the management of patients with psoriasis. Upon completion of this activity, participants should be better able to: Describe and differentiate targeting of the TYK2, JAK1, JAK2, and JAK3 kinases and the correlation to emerging therapies for the treatment of moderate to severe psoriasis, Summarize recent efficacy and safety data for current and emerging therapies for the treatment of moderate to severe psoriasis, Recommend treatment for patients with moderate to severe psoriasis according to the latest guidelines and clinical evidence, particularly as emerging therapies become available.

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast
April W. Armstrong, MD, MPH / Kenneth B. Gordon, MD - Fine-Tuning the JAK/STAT Pathway in Psoriasis: Safely Targeting the Underlying Mechanisms of Disease With TYK2 Inhibition

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast

Play Episode Listen Later Jun 14, 2022 61:45


Go online to PeerView.com/CCT860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in dermatology discuss the role of the JAK/STAT pathway in psoriasis, as well as treatment with novel kinase inhibitors for the management of patients with psoriasis. Upon completion of this activity, participants should be better able to: Describe and differentiate targeting of the TYK2, JAK1, JAK2, and JAK3 kinases and the correlation to emerging therapies for the treatment of moderate to severe psoriasis, Summarize recent efficacy and safety data for current and emerging therapies for the treatment of moderate to severe psoriasis, Recommend treatment for patients with moderate to severe psoriasis according to the latest guidelines and clinical evidence, particularly as emerging therapies become available.

You Are Nourished
[2/4] Underlying “non-food” reasons for weight gain – Stress

You Are Nourished

Play Episode Listen Later Jun 14, 2022 32:00


  Stress is our body's way of reacting to feeling under pressure. We enter the fight or flight response where our bodies go into life-saving mode to make us stay and fight or run away to escape danger. Originally this would have been vital to help us survive being attacked, whereas these days, we're in much less life-threatening situations! Unfortunately, our bodies can't tell the difference between cheating death in the claws of a predator to dealing with a stressful email! If we're not actually in physical danger, the processes going on inside our body to make us fight or flight can actually lead to weight gain and difficulties in losing weight. Today is the second in a four-part series talking about what might be going on in your body to cause you to struggle to lose weight. In this episode, I explain how our stressful modern lifestyles are damaging our health, and I share my top 5 tips to help you lead a more stress-free life. “So many health conditions can be traced back to stress.”  - Lauren Gayfer   In This Episode: Learn the impact stress has on the body. Understand that the body cannot differentiate between different types of stress. Discover what the stress hormone cortisol does to blood sugar levels and how this causes cravings. Understand the importance of dealing with the underlying issue of stress. Learn about my own struggle with stress and weight loss after having my first child. Find out my top 5 tips for reducing cortisol and managing stress better.   Resources mentioned: Get instant access to my 7 Meals in an Hour workshop where you can learn how meal prep can take away stress at mealtimes: https://www.laurengayfer.com/7-meals (https://www.laurengayfer.com/7-meals) Download my free recipe eBook with loads of lovely snack ideas that help keep your cravings under control: https://www.laurengayfer.com/healthy-snacks (https://www.laurengayfer.com/healthy-snacks) Discover loads of recipe inspiration with my bumper bundle of meal plans and recipes that will ensure you always have nourishing meals to hand: https://www.laurengayfer.com/recipe-bundle (https://www.laurengayfer.com/recipe-bundle)    Connect with Lauren:  Instagram: https://www.instagram.com/nourished.lauren/?hl=en (https://www.instagram.com/nourished.lauren/?hl=en)  Facebook: https://www.laurengayfer.com/nourished.lauren (https://www.laurengayfer.com/nourished.lauren) 

Sales Game Changers | Tip-Filled  Conversations with Sales Leaders About Their Successful Careers
How Shifting Your Underlying Belief System Will Lead to Richer Sales Success with Ian Mills

Sales Game Changers | Tip-Filled Conversations with Sales Leaders About Their Successful Careers

Play Episode Listen Later Jun 14, 2022 32:00


This is episode 519. Tips for sales career success. Read the complete transcription on the Sales Game Changers Podcast website. IAN'S TIP: "If I were to guide somebody on something they do that is potentially game-changing, what I always say to people is, go model somebody who does something that you don't do or can't do or don't believe you can do."

Wild Geese, Work, and Wonder
Season 2, Episode 3: The Underlying Privilege that Follows Vocation

Wild Geese, Work, and Wonder

Play Episode Listen Later Jun 10, 2022 32:36


In this episode we hear from Stephanie Aparicio Zambrano, a current Wild Hope Fellow, and Professor Marit Trelstad. Professor Trelstad is one of the Wild Hope leaders and is a professor of religion at Pacific Lutheran University. Stephanie and Professor Trelstad talk with the other co-hosts about what privilege is, and how it affects vocation. This is a very interesting episode to listen to!

Revive Reform Ministry
Know the underlying ideology of kings spiritual leaders and be cautious

Revive Reform Ministry

Play Episode Listen Later Jun 9, 2022 60:34


Christianity would never cause the global atrocities currently being apologized for by western countries. Religion is often...

You Are Nourished
3 underlying reasons you might be struggling to lose weight

You Are Nourished

Play Episode Listen Later Jun 7, 2022 22:42


We can eat healthily and exercise regularly, yet still find that we can't lose weight. What's important to realise is that weight loss is not as simple as calories in versus calories out. Our bodies carry out countless functions every day that are intricately linked, so it should be no surprise that there may be other things going on in the body that might prevent weight loss. Having the sole focus on weight loss can leave us feeling frustrated and demoralised as well as making conditions worse. If we take a more holistic view around improving our health, we can get to the root of any issues and treat the underlying condition. Today is the first in a four-part series talking about what might be going on in your body to cause you to struggle to lose weight. In this episode, I explain three of the most common health conditions that can make it hard to shift weight and why concentrating on weight loss can make these conditions worse. “When you are making changes to your diet and to your habits and behaviours, it's really important to start with health first.”  - Lauren Gayfer   In This Episode: Discover why there is no one size fits all when it comes to losing weight. Learn three of the most common underlying reasons for having difficulty in shifting weight. Find out how these three conditions are impacting your body. Realise that diets are a stress on the body making health conditions worse. Understand the importance of taking a holistic approach to health. Discover that focusing on changing habits and behaviours for health rather than weight loss will lead to more success.   Connect with Lauren:  Instagram: https://www.instagram.com/nourished.lauren/?hl=en (https://www.instagram.com/nourished.lauren/?hl=en)  Facebook: https://www.laurengayfer.com/nourished.lauren (https://www.laurengayfer.com/nourished.lauren)

Graced Health
The underlying reasons you are chronically exhausted (Hint: all roads lead to gut health)

Graced Health

Play Episode Listen Later Jun 7, 2022 53:17


My conversation today with Hally Brooke encompasses all things health: physical, mental and spiritual. Hally comes with such a positive energy that stems from combining a deep understanding of science with a realistic and holistic approach. She defines “nourishment” for us at one point and it was kind of like a Jerry Maguire moment. Instead of “You had me at hello,” it was “You had me at nourished.”Hally is a nationally board certified health and wellness coach as well as a functional medicine certified health coach based out of Colorado Springs, Colorado. She's also a personal trainer, avid mountain biker, dog lover, white water rafter, skier, hiker…you must know this is my kind of gal. We discuss:Chronic exhaustion, what it is, and the reasons for itSmall ways to help our chronic exhaustionSpecific vitamins most Americans are deficient in and how to increase our consumption of those nutrients (plus a bonus of what foods are good sources of those nutrients)Why the nutrient value in our food is lower than How to choose quality vitaminsSigns of poor gut healthHow Hally defines nourishment ❤️❤️❤️Links mentioned:How to pick high quality supplements guideHow to fuel your teen athlete with Roberta Anding, RD (Graced Health Podcast episode)Fight Hustle End Hurry PodcastRuthless Elimination of Hurry Book by John Mark ComerHow to have a healthy gut and why it's important with Dr. Richard Harris (Graced Health Podcast episode)Connect with Hally:www.livenourishedcoaching.comInstagram: @livenourishedcoaching and @hallybrookeFacebook: Live Nourished CoachingConnect with Amy: GracedHealth.comJoin the Graced Health community on Facebook! Instagram: @GracedHealth Facebook: @Graced Health Amy.connell@gracedhealth.comClick here to leave a review…it's simple!PurchaseYour Worthy Body: Find Freedom in Health by Breaking All the Rules

The Business Brew
BONUS: Cem Karsan - Derivatives Are The Underlying

The Business Brew

Play Episode Listen Later Jun 6, 2022 82:46


Cem Karsan stops by The Business Brew to discuss the lens he views markets through. Cem's viewpoint is unique compared to many guests on this program because he looks at how options dealers are positioned and considers what flows may result from that positioning. Many guests on this show view equity valuation as the present value of the discounted cash flows available to equity. While Cem would likely agree with that, he argues in this episode that an equity's valuation is really an output derived from the options market (which expresses probabilistic views of discounted cash flows). We hope this episode gives you something to think about! Cem Karsan formed Kai Volatility Advisors after two decades of experience building industry-leading derivatives businesses. From 1999 to 2002, he worked as a volatility trader as part of RBC Dominion Securities/ Derivatives Arbitrage Group. From 2002 to 2005, he worked under renowned Wall St. investor John Mulheren at Bear Wagner Specialists, where Cem helped expand the firm's fledgling derivatives arbitrage business into a competitive force within the industry. In 2005, Cem took a select group from the firm's proprietary trading arm and founded Precision Capital Management, specializing in equity index volatility arbitrage. The firm became a significant SPX market maker reaching, at its peak, a high of ~13% of daily trading volume.* In 2010, Cem divested his stake in Precision and fouded AEGEA Capital, the precursor to Kai Volatility Advisors. *Past performance may not be indicative of future results. Follow Cem on Twitter https://twitter.com/jam_croissant Learn more about Kai: https://www.kaivolatility.com/contact This episode is brought to you by Bastiat Partners, a boutique investment banking firm. See https://bastiatpartners.com/. Detailed show notes below. Album art photo taken by Mike Ando. Please see www.mikeando.com. Thank you to @mathewpassy (on Twitter) for the show production. Please leave us a rating in your favorite podcast player! Detailed Show Notes: Open – Cem's background 7:25 – How Cem thinks about what matters to capital markets 13:10 – Valuations have no predictive value, short term 14:10 – What happened in 2017 and why did the market seem to go up every day? 21:40 – The counterintuitive conclusion of buying and selling volatility 23:10 – Why equities are derivatives of “derivatives” 27:10 – Why options are potentially better instruments for expressing a view 32:45 – Gamma squeezes explained 38:25 – Cem's thoughts on where we are from a macro perspective 46:10 – The wealth gap and why 49:40 – Why we may be in a fundamentally inflationary environment 54:50 – The impacts of monetary policy and which generations have been hurt and helped by policy 1:00:40 – Why some medicine today may end up better in the long run 1:02:10 – The tension between utopia and the current (efficient) system 1:06:40 – Evolution and iteration will hopefully lead to better incomes 1:10:55 – The coming risks may come from exported inflation to emerging markets 1:13:10 – The winners of tomorrow used easy money to plant seeds over the past years 1:15:10 – More background on Cem

Musical Theatre Radio presents
Be Our Guest with Michael Gordon Shapiro and Aimee Reid (Gideon and the Blundersnorp)

Musical Theatre Radio presents "Be Our Guest"

Play Episode Listen Later Jun 5, 2022 30:29


Michael Gordon Shapiro Los Angeles-based Michael Gordon Shapiro composes for film, games, television, theater, and the concert hall. Classically trained, he delivers a romantic sound that blends the acoustic orchestra, evocative soloists, and organic-sounding electronics. Michael's background spans both film/television scoring and the more technical discipline of music for games. He entered the game world as audio director of Boston-based Zoesis Studios, where he composed live orchestral scores and designed the studio's adaptive music system. Michael is also an active composer for musical theatre; his children's show Super Sidekick: The Musical is published by Samuel French / Concord Theatricals and has been performed in front of young audiences throughout the United States, including Off-Broadway in 2012. His family musicals Gideon and the Blundersnorp and The Bully Problem have won numerous awards and nominations, including (for “Gideon”) Best Musical at the 2021 Hollywood Fringe Festival. Aimee Reid Aimee is a Toledo-area native, graduating from Bowling Green State University with a bachelor of arts degree in theatre for youth and puppetry. Post-bachelor's, she was admitted to Arizona State University, where she earned a Master's of Fine Arts degree in Theatre for Youth and a master's certification in nonprofit leadership and management. She teaches and directs for the Ensemble and the Young Theatre Professionals, and she leads the Creative and Brave Company (a community-based theatre program for teens, at CTW). She received the 2018 Ann Elgood Youth Theatre Director of the Year award with the American Alliance for Theatre and Education. Her favorite part about working at Children's Theatre Workshop is seeing young people fall in love with theatre and helping them make the stories their own. It is her belief that when young people tell stories, amazing things can happen. Gideon and the Blundersnorp Gideon is a stablehand who yearns to join the Royal Cavaliers. Alanna is a young viscountess who feels trapped in the system of hereditary succession. The two have more in common than they think. Thrown together by chance, Gideon and Alanna must contend with bandits, a treacherous forest, and a giant monster that just wants to eat everyone. Gideon and the Blundersnorp combines witty characters, pulse-pounding excitement, and a rousing cinematic/medieval-folk score. Underlying the fun is a positive message: aspiration is fueled by personal character, not social class.

Thoughts on the Market
Special Encore: Mid-Year Economic Outlook - Slowing or Stopping?

Thoughts on the Market

Play Episode Listen Later Jun 3, 2022 10:29


Original Release on May 17th, 2022: As we forecast the remainder of an already uncertain 2022, new questions have emerged around economic data, inflation and the potential for a recession. Chief Cross Asset Strategist Andrew Sheets and Chief Global Economist Seth Carpenter discuss.----- Transcript -----Andrew Sheets: Welcome to Thoughts on the Market. I'm Andrew Sheets. Morgan Stanley's Chief Cross-Asset Strategist. Seth Carpenter: And I'm Seth Carpenter, Morgan Stanley's Chief Global Economist. Andrew Sheets: And today on the podcast, we'll be talking about our outlook for strategy and markets and the challenges they may face over the coming months. It's Tuesday, May 17th, at 4 p.m. in London. Seth Carpenter: And it's 11 a.m. in New York. Andrew Sheets: So Seth, the global Morgan Stanley Economic and Strategy Team have just completed our mid-year outlook process. And, you know, this is a big collaborative effort where the economists think about what the global economy will look like over the next 12 months, and the strategists think about what that could mean for markets. So as we talk about that outlook, I think the economy is the right place to start. As you're looking across the global economy and thinking about the insights from across your team, how do you think the global economy will look over the next 12 months and how is that going to be different from what we've been seeing? Seth Carpenter: So I will say, Andrew, that we titled our piece, the economics piece, slowing or stopping with a question mark, because I think there is a great deal of uncertainty out there about where the economy is going to go over the next six months, over the next 12 months. So what are we looking at as a baseline? Sharp deceleration, but no recession. And I say that with a little bit of trepidation because we also try to put out alternative scenarios, the way things could be better, the way things could be worse. And I have to say, from where I'm sitting right now, I see more ways for the global economy to be worse than the global economy to be better than our baseline scenario. Andrew Sheets: So Seth, I want to dig into that a little bit more because we're seeing, you know, more and more people in the market talk about the risk of a slowdown and talk about the risk of a recession. And yet, you know, it's also hard to ignore the fact that a lot of the economic data looks very good. You know, we have one of the lowest unemployment rates that we've seen in the U.S. in some time. Wage growth is high, spending activity all looks quite high and robust. So, what would drive growth to slow enough where people could really start to think that a recession is getting more likely?Seth Carpenter: So here's how I think about it. We've been coming into this year with a fair amount of momentum, but not a perfectly pristine outlook on the economy. If you take the United States, Q1, GDP was actually negative quarter on quarter. Now, there are a lot of special exceptions there, inventories were a big drag, net exports were a big drag. Underlying domestic spending in the U.S. held up reasonably solidly. But the fact that we had a big drag in the U.S. from net exports tells you a little bit about what's going on around the rest of the world. If you think about what's going on in Europe, we feel that the economy in the eurozone is actually quite precarious. The Russian invasion of Ukraine presents a clear and critical risk to the European economy. I mean, already we've seen a huge jump in energy prices, we've seen a huge jump in food prices and all of that has got to weigh on consumer spending, especially for consumers at the bottom end of the income distribution. And what we see in China is these wave after wave of COVID against the policy of COVID zero means that we're going to have both a hit to demand from China and some disruption to supply. Now, for the moment, we think the disruption to supply is smaller than the hit to demand because there is this closed loop approach to manufacturing. But nevertheless, that shock to China is going to hurt the global economy. Andrew Sheets: So Seth, the other major economic question that's out there is inflation, and you know where it's headed and what's driving it. So I was hoping you could talk a little bit about what our forecasts for inflation look like going forward. Seth Carpenter: Our view right now is that inflation is peaking or will be peaking soon. I say that again with a fair amount of caution because that's been our view for quite some time, and then we get these additional surprises. It's clear that in many, many economies, a huge amount of the inflation that we are seeing is coming from energy and from food. Now energy prices and food prices are not likely to fall noticeably any time soon. But after prices peak, if they go sideways from there, the inflationary impulse ends up starting to fade away and so we think that's important. We also think, the COVID zero policy in China notwithstanding, that there will be some grudging easing of supply chain frictions globally, and that's going to help bring down goods inflation as well over time. So we think inflation is high, we think inflation will stay high, but we think that it's roughly peaked and over the balance of this year and into next year it should be coming down.Andrew Sheets: As you think about central bank policy going forward, what do you think it will look like and do you think it can get back to, quote, normal? Seth Carpenter: I will say, when it comes to monetary policy, that's a question we want to ask globally. Right now, central banks globally are generically either tight or tightening policy. What do I mean by that? Well, we had a lot of EM central banks in Latin America and Eastern Europe that had already started to hike policy a lot last year, got to restrictive territory. And for those central banks, we actually see them starting to ease policy perhaps sometimes next year. For the rest of EM Asia, they're on the steady grind higher because even though inflation had started out being lower in the rest of EM Asia than in the developed market world, we are starting to see those inflationary pressures now and they're starting to normalize policy. And then we get to the developed market economies. There's hiking going on, there's tightening of policy led by the Fed who's out front. What does that mean about getting back to an economy like we had before COVID? One of the charts that we put in the Outlook document has the path for the level of GDP globally. And you can clearly see the huge drop off in the COVID recession, the rapid rebound that got us most of the way, but not all the way back to where we were before COVID hit. And then the question is, how does that growth look as we get past the worst of the COVID cycle? Six months ago, when we did the same exercise, we thought growth would be able to be strong enough that we would get our way back to that pre-COVID trend. But now, because supply has clearly been constrained because of commodity prices, because of labor market frictions, monetary policy is trying to slow aggregate demand down to align itself with this restricted supply. And so what that means is, in our forecast at least, we just never get back to that pre-COVID trend line. Seth Carpenter: All right, Andrew, but I've got a question to throw back at you. So the interplay between economics and markets is really uncertain right now. Where do you think we could be wrong? Could it be that the 3%, ten-year rate that we forecast is too low, is too high? Where do you think the risks are to our asset price forecasts? Andrew Sheets: Yeah, let me try to answer your question directly and talk about the interest rate outlook, because we are counting on interest rates consolidating in the U.S. around current levels. And our thinking is partly based on that economic outlook. You know, I think where we could be wrong is there's a lot of uncertainty around, you know, what level of interest rate will slow the economy enough to balance demand and supply, as you just mentioned. And I think a path where U.S. interest rates for, say, ten year treasuries are 4% rather than 3% like they are today, I think that's an environment where actually the economy is a little bit stronger than we expect and the consumer is less impacted by that higher rate. And it's going to take a higher rate for people to keep more money in savings rather than spending it in the economy and potentially driving that inflation. So I think the path to higher rates and in our view does flow through a more resilient consumer. And those higher rates could mean the economy holds up for longer but markets still struggle somewhat, because those higher discount rates that you can get from safe government bonds mean people will expect, mean people will expect a higher interest rate on a lot of other asset classes. In short, we think the risk reward here for bonds is more balanced. But I think the yield move so far this year has been surprising, it's been historically extreme, and we have to watch out for scenarios where it continues. Seth Carpenter: Okay. That's super helpful. But another channel of transmission of monetary policy comes through exchange rates. So the Fed has clearly been hiking, they've already done 75 basis points, they've lined themselves up to do 50 basis points at at least the next two meetings. Whereas the ECB hasn't even finished their QE program, they haven't started to raise interest rates yet. The Bank of Japan, for example, still at a really accommodative level, and we've seen both of those currencies against the dollar move pretty dramatically. Are we in one of those normal cycles where the dollar starts to rally as the Fed begins to hike, but eventually peaks and starts to come off? Or could we be seeing a broader divergence here? Andrew Sheets: Yeah. So I think this is to your point about a really interesting interplay between markets and Federal Reserve policy, because what the Fed is trying to do is it's trying to slow demand to bring it back in line with what the supply of things in the economy can provide at at current prices rather than it at higher prices, which would mean more inflation. And there's certainly an important interest rate part to that slowing of demand story. There's a stock market part of the story where if somebody's stock portfolio is lower, maybe they're, again, a little bit less inclined to spend money and that could slow the economy. But the currency is also a really important element of it, because that's another way that financial markets can feed back into the real economy and slow growth. And if you know you're an American company that is an exporter and the dollar is stronger, you likely face tougher competition against overseas sellers. And that acts as another headwind to the economy. So we think the dollar strengthens a little bit, you know, over the next month or two, but ultimately does weaken as the market starts to think enough is priced into the Fed. We're not going to get more Federal Reserve interest rates than are already implied by the market, and that helps tamp down some of the dollar strength that we've been seeing. Andrew Sheets: And Seth thanks for taking the time to talk. Seth Carpenter: Andrew, it's been great talking to you. Andrew Sheets: And thanks for listening. If you enjoy Thoughts on the Market, please leave us a review on Apple Podcasts and share the podcast with a friend or colleague today.

THE GRIZ PODCAST
E-172: School Shootings - The Real Underlying Problems!

THE GRIZ PODCAST

Play Episode Listen Later Jun 1, 2022 56:17


Clare 's Podcast
'The notion of a separate organism is clearly an abstraction, as is also its boundary.' David Bohm, Wonder-Full Words

Clare 's Podcast

Play Episode Listen Later May 28, 2022 6:33


The notion of a separate organism is clearly an abstraction, as is also its boundary. Underlying all this is unbroken wholeness even though our civilization has developed in such a way as to strongly emphasize the separation into parts. David Bohm

Perfectly You Podcast
91. The symptoms reveal the underlying disease

Perfectly You Podcast

Play Episode Listen Later May 24, 2022 27:22


What you see is the comment on social media. The angry reaction. The eye roll. The snarky tone.    You snap at the waiter. At your kid. At your boss. At your husband. Your blood is boiling.   "I didn't mean to," or rather..."I wish YOU had not heard that."

Nomura Podcasts
Fireside Chats - Asia Insights: Taking the Temperature of Asia's Underlying Inflation

Nomura Podcasts

Play Episode Listen Later May 18, 2022 25:39


In this episode of our Fireside Chats series we'll be talking with Rob Subbaraman and Sonal Varma from the Global Economics team on the state of Asia's underlying inflation and what it means for the Macro outlook.

Book Insights Podcast
Depression's Underlying Cause | Book Insight on Lost Connections by Johann Hari

Book Insights Podcast

Play Episode Listen Later May 18, 2022 30:59


*Prompted by his own experience of living with depression and the escalating levels of depression and anxiety across the Western world, Johann Hari set out on a three-year investigation, interviewing experts and sufferers the world over. *He questions the conventional wisdom about depression – essentially that it's all in our heads, caused by an imbalance in our brain chemistry – and the efficacy of antidepressants. *Looking outside our heads, rather than within, Hari argues, we can identify an alternative source for the rise in mental-health issues: disconnection from truly rewarding work, from other people, from meaningful values to live by, and even from the natural world. *To improve our mental health, we need to seek connections – renewing links with others, finding fulfilling work, building better cultural values and tapping into our spiritual sides. *In short, better mental health is a society-wide effort, rather than a matter confined to doctor and patient. Theme 1: Effectiveness of Antidepressants - 0:29 Theme 2: The True Causes of Depression - 8:40 Theme 3: 7 Alternative Forms of Antidepressant - 20:08 Like what you hear? Be sure to like & subscribe to support this podcast! Also leave a comment and let us know your thoughts on the episode. You can also get a free weekly email about the Book Insight of the week. Subscribe at memod.com/insights Want quick save-able, share-able bullet points on this book? Check out the Memo: https://insights.memod.com/the-body-keeps-the-score HEAR THE FULL INTERVIEWS MENTIONED IN TODAYS' EPISODE HERE: YouTube. (2019). Johann Hari: The Antidote for Loneliness. [online] Available at: https://www.youtube.com/watch?v=bC2Na1E3iVg. YouTube. (2019). Johann Hari: To Treat Depression, Provide Meaningful Work, Housing & a Basic Income, Not Just Drugs. [online] Available at: https://www.youtube.com/watch?v=OdSFliBttQI. YouTube. (2019). Loneliness kills: How to fight depression with social support | Johann Hari. [online] Available at: https://www.youtube.com/watch?v=Hp-L844-5k8. Full Title: Lost Connections: Uncovering the Real Causes of Depression - and the Unexpected Solutions Year of Publication: 2018 Book Author: Johann Hari To purchase the complete edition of this book click here: https://www.amazon.com/dp/B078HSDZSQ/ref=cm_sw_em_r_mt_dp_GQWGNZTMKPAR7BJPF677 Book Insight Writer: Laura Gladwin Editor: Tom Butler-Bowdon Producer: Daniel Gonzalez Production Manager: Karin Richey Curator: Tom Butler-Bowden Narrator: Tom Evans

The Infertility Stress Podcast
42. The Underlying Reason Why Infertility Is So Stressful

The Infertility Stress Podcast

Play Episode Listen Later May 18, 2022 11:12


In today's episode, I'm discussing the reasons why infertility is stressful. I review some of the obvious reasons why people struggle first. And then I dive into some of the deeper reasons including Our socialization as women Our cultural conditioning about our purpose as women And then I offer some questions to ask and an exercise for how to start to unpack this. IMPORTANT LINKS Grab The Infertility Stress Relief Toolkit For FREE Sign Up For Michelle's Email List

Thoughts on the Market
Mid-Year Economic Outlook: Slowing or Stopping?

Thoughts on the Market

Play Episode Listen Later May 18, 2022 10:22


As we forecast the remainder of an already uncertain 2022, new questions have emerged around economic data, inflation and the potential for a recession. Chief Cross Asset Strategist Andrew Sheets and Chief Global Economist Seth Carpenter discuss.-----Transcript-----Andrew Sheets: Welcome to Thoughts on the Market. I'm Andrew Sheets. Morgan Stanley's Chief Cross-Asset Strategist. Seth Carpenter: And I'm Seth Carpenter, Morgan Stanley's Chief Global Economist. Andrew Sheets: And today on the podcast, we'll be talking about our outlook for strategy and markets and the challenges they may face over the coming months. It's Tuesday, May 17th, at 4 p.m. in London. Seth Carpenter: And it's 11 a.m. in New York. Andrew Sheets: So Seth, the global Morgan Stanley Economic and Strategy Team have just completed our mid-year outlook process. And, you know, this is a big collaborative effort where the economists think about what the global economy will look like over the next 12 months, and the strategists think about what that could mean for markets. So as we talk about that outlook, I think the economy is the right place to start. As you're looking across the global economy and thinking about the insights from across your team, how do you think the global economy will look over the next 12 months and how is that going to be different from what we've been seeing? Seth Carpenter: So I will say, Andrew, that we titled our piece, the economics piece, slowing or stopping with a question mark, because I think there is a great deal of uncertainty out there about where the economy is going to go over the next six months, over the next 12 months. So what are we looking at as a baseline? Sharp deceleration, but no recession. And I say that with a little bit of trepidation because we also try to put out alternative scenarios, the way things could be better, the way things could be worse. And I have to say, from where I'm sitting right now, I see more ways for the global economy to be worse than the global economy to be better than our baseline scenario. Andrew Sheets: So Seth, I want to dig into that a little bit more because we're seeing, you know, more and more people in the market talk about the risk of a slowdown and talk about the risk of a recession. And yet, you know, it's also hard to ignore the fact that a lot of the economic data looks very good. You know, we have one of the lowest unemployment rates that we've seen in the U.S. in some time. Wage growth is high, spending activity all looks quite high and robust. So, what would drive growth to slow enough where people could really start to think that a recession is getting more likely?Seth Carpenter: So here's how I think about it. We've been coming into this year with a fair amount of momentum, but not a perfectly pristine outlook on the economy. If you take the United States, Q1, GDP was actually negative quarter on quarter. Now, there are a lot of special exceptions there, inventories were a big drag, net exports were a big drag. Underlying domestic spending in the U.S. held up reasonably solidly. But the fact that we had a big drag in the U.S. from net exports tells you a little bit about what's going on around the rest of the world. If you think about what's going on in Europe, we feel that the economy in the eurozone is actually quite precarious. The Russian invasion of Ukraine presents a clear and critical risk to the European economy. I mean, already we've seen a huge jump in energy prices, we've seen a huge jump in food prices and all of that has got to weigh on consumer spending, especially for consumers at the bottom end of the income distribution. And what we see in China is these wave after wave of COVID against the policy of COVID zero means that we're going to have both a hit to demand from China and some disruption to supply. Now, for the moment, we think the disruption to supply is smaller than the hit to demand because there is this closed loop approach to manufacturing. But nevertheless, that shock to China is going to hurt the global economy. Andrew Sheets: So Seth, the other major economic question that's out there is inflation, and you know where it's headed and what's driving it. So I was hoping you could talk a little bit about what our forecasts for inflation look like going forward. Seth Carpenter: Our view right now is that inflation is peaking or will be peaking soon. I say that again with a fair amount of caution because that's been our view for quite some time, and then we get these additional surprises. It's clear that in many, many economies, a huge amount of the inflation that we are seeing is coming from energy and from food. Now energy prices and food prices are not likely to fall noticeably any time soon. But after prices peak, if they go sideways from there, the inflationary impulse ends up starting to fade away and so we think that's important. We also think, the COVID zero policy in China notwithstanding, that there will be some grudging easing of supply chain frictions globally, and that's going to help bring down goods inflation as well over time. So we think inflation is high, we think inflation will stay high, but we think that it's roughly peaked and over the balance of this year and into next year it should be coming down.Andrew Sheets: As you think about central bank policy going forward, what do you think it will look like and do you think it can get back to, quote, normal? Seth Carpenter: I will say, when it comes to monetary policy, that's a question we want to ask globally. Right now, central banks globally are generically either tight or tightening policy. What do I mean by that? Well, we had a lot of EM central banks in Latin America and Eastern Europe that had already started to hike policy a lot last year, got to restrictive territory. And for those central banks, we actually see them starting to ease policy perhaps sometimes next year. For the rest of EM Asia, they're on the steady grind higher because even though inflation had started out being lower in the rest of EM Asia than in the developed market world, we are starting to see those inflationary pressures now and they're starting to normalize policy. And then we get to the developed market economies. There's hiking going on, there's tightening of policy led by the Fed who's out front. What does that mean about getting back to an economy like we had before COVID? One of the charts that we put in the Outlook document has the path for the level of GDP globally. And you can clearly see the huge drop off in the COVID recession, the rapid rebound that got us most of the way, but not all the way back to where we were before COVID hit. And then the question is, how does that growth look as we get past the worst of the COVID cycle? Six months ago, when we did the same exercise, we thought growth would be able to be strong enough that we would get our way back to that pre-COVID trend. But now, because supply has clearly been constrained because of commodity prices, because of labor market frictions, monetary policy is trying to slow aggregate demand down to align itself with this restricted supply. And so what that means is, in our forecast at least, we just never get back to that pre-COVID trend line. Seth Carpenter: All right, Andrew, but I've got a question to throw back at you. So the interplay between economics and markets is really uncertain right now. Where do you think we could be wrong? Could it be that the 3%, ten-year rate that we forecast is too low, is too high? Where do you think the risks are to our asset price forecasts? Andrew Sheets: Yeah, let me try to answer your question directly and talk about the interest rate outlook, because we are counting on interest rates consolidating in the U.S. around current levels. And our thinking is partly based on that economic outlook. You know, I think where we could be wrong is there's a lot of uncertainty around, you know, what level of interest rate will slow the economy enough to balance demand and supply, as you just mentioned. And I think a path where U.S. interest rates for, say, ten year treasuries are 4% rather than 3% like they are today, I think that's an environment where actually the economy is a little bit stronger than we expect and the consumer is less impacted by that higher rate. And it's going to take a higher rate for people to keep more money in savings rather than spending it in the economy and potentially driving that inflation. So I think the path to higher rates and in our view does flow through a more resilient consumer. And those higher rates could mean the economy holds up for longer but markets still struggle somewhat, because those higher discount rates that you can get from safe government bonds mean people will expect, mean people will expect a higher interest rate on a lot of other asset classes. In short, we think the risk reward here for bonds is more balanced. But I think the yield move so far this year has been surprising, it's been historically extreme, and we have to watch out for scenarios where it continues. Seth Carpenter: Okay. That's super helpful. But another channel of transmission of monetary policy comes through exchange rates. So the Fed has clearly been hiking, they've already done 75 basis points, they've lined themselves up to do 50 basis points at at least the next two meetings. Whereas the ECB hasn't even finished their QE program, they haven't started to raise interest rates yet. The Bank of Japan, for example, still at a really accommodative level, and we've seen both of those currencies against the dollar move pretty dramatically. Are we in one of those normal cycles where the dollar starts to rally as the Fed begins to hike, but eventually peaks and starts to come off? Or could we be seeing a broader divergence here? Andrew Sheets: Yeah. So I think this is to your point about a really interesting interplay between markets and Federal Reserve policy, because what the Fed is trying to do is it's trying to slow demand to bring it back in line with what the supply of things in the economy can provide at at current prices rather than it at higher prices, which would mean more inflation. And there's certainly an important interest rate part to that slowing of demand story. There's a stock market part of the story where if somebody's stock portfolio is lower, maybe they're, again, a little bit less inclined to spend money and that could slow the economy. But the currency is also a really important element of it, because that's another way that financial markets can feed back into the real economy and slow growth. And if you know you're an American company that is an exporter and the dollar is stronger, you likely face tougher competition against overseas sellers. And that acts as another headwind to the economy. So we think the dollar strengthens a little bit, you know, over the next month or two, but ultimately does weaken as the market starts to think enough is priced into the Fed. We're not going to get more Federal Reserve interest rates than are already implied by the market, and that helps tamp down some of the dollar strength that we've been seeing. Andrew Sheets: And Seth thanks for taking the time to talk. Seth Carpenter: Andrew, it's been great talking to you. Andrew Sheets: And thanks for listening. If you enjoy Thoughts on the Market, please leave us a review on Apple Podcasts and share the podcast with a friend or colleague today.

The Michael Yardney Podcast | Property Investment, Success & Money
The RBA forecasts what's ahead – and it has flip flopped, with Dr. Andrew Wilson

The Michael Yardney Podcast | Property Investment, Success & Money

Play Episode Listen Later May 11, 2022 27:06


The Reserve Bank thought it had time on its hands and could be patient in lifting interest rates. However, evidence of strong inflation caught the RBA by surprise and it has raised its forecasts for inflation and cut its forecasts for economic growth and unemployment. The RBA forecasts that the economy will expand by 3.5 per cent over the year to June 2022, before picking up to a 4.25 per cent annual growth rate in December 2022. Underlying inflation is expected to exceed the top of the 2-3 per cent target band through to December 2023. Links and Resources: Michael Yardney Get the team at Metropole to help build your personal Strategic Property Plan Click here and have a chat with us Dr. Andrew Wilson, Chief Economist My Housing Market Subscribe to our weekly Property Insiders videos – www.PropertyInsiders.info Get your bundle of eBooks and reports at www.PodcastBonus.com.au Shownotes plus more here: The RBA forecasts what's ahead – and it has flip-flopped, with Dr Andrew Wilson  

Chicago Psychology Podcast
Super Simple CBT & Emotional Healing with Matt McKay, Ph.D.

Chicago Psychology Podcast

Play Episode Listen Later May 9, 2022 74:44


Dr. Matthew McKay, PhD is a professor at the Wright Institute in Berkeley, CA. He has authored and co-authored numerous books, including Self-Esteem, The Relaxation and Stress Reduction Workbook, Thoughts and Feelings, and ACT on Life Not on Anger. His books combined have sold more than four million copies. He received his PhD in clinical psychology from the California School of Professional Psychology, and specializes in the cognitive behavioral treatment of anxiety and depression. Among other accolades, he is the founder of New Harbinger Press. Dr. McKay and Dr. Hoye discuss two new books he has co-authored, Super Simple CBT: 6 Skills to Improve Your Mood in Minutes, and the Healing Emotional Pain Workbook. Topics include:•Process CBT vs. Classic CBT•The role of spirituality in healing and psychotherapy •Underlying psychological causes and constructs of psychiatric disorders and how to approach them systematicallySuper Simple CBT:https://www.amazon.com/Super-Simple-CBT-Improve-Minutes/dp/1684038693The Healing Emotional Pain Workbook:https://www.amazon.com/Healing-Emotional-Pain-Workbook-Process-Based/dp/1648480217/ref=sr_1_1?crid=AMM5TGJQ840N&keywords=Healing+Emotional+Pain+workbook&qid=1651008039&s=books&sprefix=healing+emotional+pain+workbook%2Cstripbooks%2C60&sr=1-1The Psychology Talk Podcast is a unique conversation about psychology around the globe. Your host Dr. Scott Hoye talks about psychology and behavioral health with mental health practitioners and experts to keep you informed about issues and trends in the industry.https://psych-talk.com https://www.instagram.com/psychtalkpodcast/

MTMV Sports Podcast Network
The Underlying Issue with the Tee Morant Hate (NTSP SZN 2 EP 3)

MTMV Sports Podcast Network

Play Episode Listen Later May 9, 2022 61:48


Rob & C touch on the hot topic of the Hate Ja Morant's father is getting and why it's an issue. In the music section they share the best songs they have heard regardless of genre. Plus songs by Vic Lucas & the G.O.M. Squad. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Working for the Word
The Bible in Arabic - part 10 - underlying assumptions for BT with Dr. Aaron Shryock

Working for the Word

Play Episode Listen Later May 7, 2022 53:32


What are the underlying assumptions that might influence our choice of how to translate the Bible into Arabic, and also in other Muslim contexts? We're going to step back in this episode and try to understand what presuppositions might be driving certain ideas in this debate. In order to do that, Dr. Aaron Shryock has kindly agreed to contribute his perspective. This will be interesting, because I'm sure there are a lot of people who would disagree strongly with his view, but I hope that we can all learn together by listening and trying to empathize with different convictions and positions in the world of translation. Books Aaron recommends: Translating the Bible in Plain Language by de Jong Muslim Conversions to Christ Aaron's website Aaron's email: aaron@horizonsinternational.org my books | twitter | music | Hebrew | academic articles | facebook | contact | download all episodes for offline

Not the Same Podcast
The Underlying Issue With The Tee Morant Hate | SZN2 EP#3

Not the Same Podcast

Play Episode Listen Later May 6, 2022 61:18


Rob & C chop it up about various faith & music topics… Plus: 6:05 | What's Good? 6:10 | Faith Segment 6:20 | Music Video: All On Him ft Xay Hill | by Vic Lucas 6:25 | CHH/Music Segment 6:45 | Music Video: Payback ft Bizzle, Datin, Jered Sanders & A.I. The Anomaly | by God Over Money --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/notthesamepodcast/support

In Your Head with Leigh Richardson
Discover Underlying Health Issues that Affect Us and How The Listening Program Can Help With Them

In Your Head with Leigh Richardson

Play Episode Listen Later May 6, 2022 56:24


Compliance Perspectives
Steven Melinosky on Conflicts of Interest in Healthcare and Elsewhere [Podcast]

Compliance Perspectives

Play Episode Listen Later May 5, 2022 12:03


Posted by Adam Turteltaub Conflicts of interest are a particularly challenging issue in healthcare.  Medical professionals may moonlight at a rival hospital, have an interest in a medical device or real estate a hospital is thinking of acquiring, and, of course, family members who might work at a key vendor. Steven Melinosky, Regional Director Compliance/Investigations and Policy at Trinity Health of New England, explains in this podcast that managing conflicts of interest is possible, with the right policies and procedures in place. That begins with recognizing that one policy is likely not enough.  The conflicts faced by leadership and the board are likely quite different than those faced by rank-and-file employees.  Conflicts for senior leaders and board members likely should be reviewed by the board chair.  Those for employees can typically be handled by the compliance team working with frontline managers. Underlying  these efforts must be a culture of compliance from the top down and bottom up.  The danger of conflicts of interest must be taught from day one, along with encouragement to report and a clear explanation of the disclosure process.  Supervisors need to be trained to identify conflicts, and periodic reminders need to be scheduled. One tool that can help make conflict of interest management simpler is something he created and calls a “Conflict of Interest Dictionary.”  It is a spreadsheet designed to help respond to common conflicts.  It contains several columns: What the conflict is What else needs to be known about it, such as if the individual affected has purchasing authority, is in management and at what level Why this issue poses a conflict Standardized action plans that lay out expectations for behavior Having this dictionary helps to ensure consistency in the process and greatly expedites actions since a starting point (and potentially an ending post) is already in place. Along with this dictionary it's important to take the time to assess the risk – both likelihood and potential impact – of a conflict and to ensure that the plans put in place are sufficient to mitigate the risk. He also recommends providing both the affected employee and his or her manager with a written plan which includes the background, the risks and expectations. Listen in to learn more about how to better manage conflicts of interest and whether a Conflict of Interest Dictionary is right for your program.

Ninkas Detox
#122: ARE AUTISM TESTS & DIAGNOSIS ACCURATE?

Ninkas Detox

Play Episode Listen Later May 4, 2022 30:45


Here's a crazy real-life example that will make you question the screening and tests like DSM-5 and ADOS. What would you do if someone locked up to your child because of a diagnosis that shouldn't ever have been given?Horrific, right.Get this...If a diabetic has severe hypoglycemia - that person looks like a drunk. In some instances - diabetics have been arrested because of "drunk" behaviour caused by hypoglycemia. If that person isn't examined by someone who knows about diabetes and the underlying cause for this behaviour...It can have fatal consequences. EXPERTISE in UNDERLYING root causes is CRUCIAL because without it, we can ruin someones life, health and future...We wouldn't send a child with a broken leg to a brain expert, would we?Yet...we're sending children with physical, biological, mitochondrial, neurological, and immune-related problems to psychiatrists or behaviour analysts to diagnose our children....They are given a diagnosis that will affect them for life and change their future without knowing that the expert aren't looking at root cause problems that can be addressed (and affect the symptoms.)In today's short-form Q & A podcast episode I am answering the question: Are autism tests accurate? When I found the answer AFTER my son was diagnosed I was both shocked and angry...

What’s Your Emergency
Everything's Bigger in Texas...Except Cop's Waistlines.

What’s Your Emergency

Play Episode Listen Later May 4, 2022 32:35


Yes, you read that right. Everything is bigger in Texas, except your belt, apparently. Wyoming says no.We all know slugs on the job in Fire, Police and EMS but can we really judge a person's fitness simply by the size of their waistline? Texas DPS says yes.Listen in to see what the guys think and take a peek at this article which lists law enforcement as the most obese profession in America. Before you laugh too hard, fellow firefighters, we tied for second along with Security Guards.Underlying point about all this? Sometimes rules are stupid and sometimes we need to take a hint and maybe skip the 2800 calorie “coffee” drink in the morning and walk the dog an extra day this week.Support the show

Cardionerds
199. Case Report: The Perfect Storm of Complications Post-Partum – Summa Health

Cardionerds

Play Episode Listen Later May 4, 2022 40:20


CardioNerds (Amit Goyal and Daniel Ambinder) join Dr. Phoo Pwint Nandar (former FIT Ambassador), Dr. Deep Shah (current FIT Ambassador), and Dr. Sugat Wagle from the Summa Health Cardiology Department for an afternoon at Cuyahoga National Valley Park. We discuss a case of a post-partum woman who presented with ventricular fibrillation arrest due to SCAD. She had ongoing advanced cardiac life support (ACLS) for nearly 60 minutes before obtaining return of spontaneous circulation. We discuss the broad differential of VF arrest, including acute coronary syndrome and spontaneous coronary artery dissection (SCAD) – among many others. We also go over the etiology and management of SCAD as well the complications. Pregnancy is a crucial stressor to the cardiovascular system and understanding its hemodynamic changes is crucial to all physicians. The E-CPR segment is provided by Dr. Grace Ayafor, Interventional cardiology faculty, Summa Health. Jump to: Case media - Case teaching - References CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Case Media Episode Schematics & Teaching - SCAD Pearls - SCAD SCAD remains underdiagnosed. It has a wide range of clinical presentations, including chest pain, ACS, VT/VF arrest, and cardiogenic shock.Underlying etiologies of SCAD include autoimmune diseases, connective tissue disorders, fibromuscular dysplasia, external stressors, and pregnancy.There are 3 types of SCAD, and coronary angiogram is the gold standard for diagnosis.Common areas of involvement of SCAD include left anterior descending and left circumflex arteries; however, SCAD can manifest in any coronary artery as well as simultaneously in multiple coronary arteries. Left main trunk involvement is rare, more likely to be associated with the peri-partum state, and requires complex management decisions guided by a heart team approach.Most SCAD cases are benign and treated conservatively, however, some require intervention (PCI or CABG) depending on clinical severity and course.Recurrent SCAD has been reported in 10-30% of the patients and aggressive management of hypertension is recommended.Guidelines regarding SCAD management are largely based on expert consensus due to a dearth of high-quality data. Efforts to raise awareness and study this syndrome are of paramount importance. Notes - SCAD 1. What is SCAD and how does it present? Spontaneous coronary artery dissection (SCAD) is defined as an epicardial coronary dissection that is not associated with atherosclerosis or instrumentation.This occurs with hematoma formation within the tunica media,  thereby potentially compressing the arterial true lumen leading to ischemia.There are two proposed mechanisms of hematoma formation: “inside-out” and “outside-in”. The inside-out hypothesis posits that the hematoma arises from the true lumen via a dissection flap – an endothelial-intimal disruption. Conversely the outside-in hypothesis posits that the hematoma arises de novo within the media through disruption of traversing microvessels.There is a wide range of clinical presentation for SCAD varying in severity including asymptomatic / benign presentation, anginal syndromes, acute myocardial infarction, VT/VF arrest, and cardiogenic shock. Our patient presented with VF arrest and ACS.SCAD epidemiology is confounded by a lack of awareness. A high index of suspicion is warranted. Diagnosis can be missed in young or mid-life without CV risk factors who would present with atypical/mild chest pain. 2. What are the etiologies of SCAD? SCAD is associated with the peripartum state (presumed due to combination of hormonal mediated vessel wall integrity changes and hemodynamic stressors), illicit substance use, autoimmune disorders,

The Kevin Jackson Show
Ep. 22-174 - Underlying Speech

The Kevin Jackson Show

Play Episode Listen Later May 3, 2022 38:40


In this episode, Jill Biden's embarrassingly low sales in debut week. The mysterious hero 'ghost of Kyiv' fighter revealed. When 'Free Speech' collides with disinformation to millions.

TonioTimeDaily
10 Myths About Non-Binary People It's Time to Unlearn

TonioTimeDaily

Play Episode Listen Later May 1, 2022 88:33


"Myth #1: You Are Trying to Be ‘Special Snowflakes' (Or ‘This Is Just a Fad') This stereotype comes with the assumption that we're spoiled and looking for attention by trying to be unique. In actuality, this is simply our experience of gender, and it has nothing to do with “fads,” although I like to think we can be a fashionable bunch! Common phrases that adhere to this stereotype include, “You can still wear whatever you want and be a girl/boy,” and “Just pick one already.” When people say these things, they overlook the difference between gender identity and gender expression. Non-binary people can express our genders in any way that works for us, but at the end of the day, our gender identities still don't fit solely into “male” or “female.” For a non-binary person, choosing between being male or female is simply not an option. The range of non-binary gender identities is nearly boundless — and so are the words we use to describe ourselves. Here is a list of some of those words. Our diversity, far from invalidating our identities, is at the heart of who we are. Myth #2: You're Just Confused Being non-binary does not mean that we're confused about our genders. It simply means that our gender is not solely male or female, or that we have no gender. Underlying this myth is the idea that because others are often confused by us, there is no way that we could actually be sure about being non-binary. There also is the assumption that if we're confused, then it's okay for people to decide how to refer to us. However, there is absolutely nothing wrong with being confused about your gender! Confusion is completely normal and a part of many trans people's process. What is unacceptable, though, is invalidating people's genders because they're still figuring things out. No matter what, others should affirm and respect our genders." --- Send in a voice message: https://anchor.fm/antonio-myers4/message Support this podcast: https://anchor.fm/antonio-myers4/support

Marketplace Minute
GDP falls, but underlying economy shows strength - Closing Bell - Marketplace Minute - April 28, 2022

Marketplace Minute

Play Episode Listen Later Apr 28, 2022 1:50


Stocks rise; business investment and consumer spending stay strong; new unemployment claims fall; Unilever sales volume drops

Audible Bleeding
Holding Pressure Case Prep - BKA/AKA

Audible Bleeding

Play Episode Listen Later Apr 28, 2022 21:59


Holding Pressure AKA/BKA Shownotes   Name of Surgery: Above Knee Amputation/Below Knee Amputation   Authors: Dominique Dockery, MS3, Alpert Medical School of Brown University Robert Patterson, MD, FACS, Alpert Medical School of Brown University/Providence Surgical Care Group   Editor:  Yasong Yu   Reviewer: Ryan Meyer   Core Resources: Rutherford's Vascular and Endovascular Therapy 9th Edition Chapters 104, 105, 111, 112 Anson and McVeigh's Surgical Anatomy   Additional Resources: Article Explaining WIfI (https://www.jvascsurg.org/article/S0741-5214(13)01515-2/fulltext)  Links to Apps for CLTI Calculators (https://vascular.org/news-advocacy/society-vascular-surgery-launches-mobile-apps-staging-chronic-limb-threatening)  Callander Technique Original Article (https://jamanetwork.com/journals/jama/article-abstract/1155011) Logan, Meryl Simon & Bush, Ruth L. Vascular surgeons are health disparities doctors. JVS. Vol 74; Issue 5p1437. November 2021.    Underlying disease featured in episode: Peripheral arterial disease (PAD)/chronic limb threatening ischemia (CLTI) Pathophysiology/etiology Blockage of the arteries supplying blood to the lower limbs usually secondary to atherosclerosis Affects an estimated 8-12 million Americans Associated with smoking, diabetes, hypertension, obesity CLTI is more severe form of PAD (up to 20% of PAD patients)- associated with rest pain, ischemia ulceration, or gangrene Patient presentation Varies based on disease progression and prior intervention Ranges from asymptomatic to major tissue loss Often have patients with intermittent claudication, rest pain, or wounds/ulceration Patients can be classified using Rutherford scale or WIfI classification Diagnosis Ankle-brachial index is diagnostic (1.3) Often obtain CTA with run-off to visualize vessels prior to angiogram Angiogram to plan intervention Surgical treatment  Revascularization: either endovascular (angioplasty vs stenting) or open (bypass based on targets with either vein or graft) Amputation: after failed revascularization or irreversible/severe ischemia with no revascularization options Minor (toe/foot) vs major (below knee/through knee/above knee)   Indications for surgery:  acute ischemia: for irreversible ischemia, for severe ischemia with no revascularization options, or following unsuccessful attempts at revascularization chronic ischemia: failure of revascularization, lack of suitable conduit or target arteries, severe patient comorbidities, poor functional status, or extensive gangrene or infection such that foot salvage is not possible foot infection severe traumatic injury lower extremity skeletal or soft tissue malignancy   Preop Preparation: linking the patient with a prosthetist prior to surgery is ideal and helps with surgical planning, addressing patients' fears and concerns, determining level of amputation (pulses/blood flow, level of infection, etc.)   Surgical steps with relevant images:  Below the knee amputation (posterior flap technique): Create a hemi-circular incision anteriorly (generally about 1 handbreadth below the tibial tuberosity that goes from just anterior to the fibula to an equidistant portion of the other side) and a long posterior flap  Cut through the muscles of the anterior compartment (muscle bundle on the lateral side of the tibia) and expose the anterior tibial artery and vein- ligate and suture ligate Using a periosteal elevator, which is something like a chisel, strip the periosteum proximally from the tibia and divide the tibia with an oscillating saw. Then strip the periosteum and attachments of the fibula at this level and divide either with the saw or a bone shear.  Use an amputation knife to create the posterior flap along the skin and fascia incision lines (fashion it to make sure it will reach anteriorly without muscle bulk/tension). The remaining tibial vessels are then identified and individually suture ligated. Identify the tibial nerve, bluntly dissect it quite proximally and divide it with electrocautery.  After hemostasis has been established, remove a wedge of bone from the anterior portion of the tibia so that that doesn't provide a pressure point on the prosthesis and resect the fibula 1-2 centimeters above the line of tibial transection with a rib cutter to be sure that the fibula doesn't wear against the prosthesis laterally and create an ulceration or painful protrusion. Loosely approximate the posterior flap to the anterior fascia with several interrupted Vicryl sutures and then carefully re-approximate the skin with vertical mattress sutures of Prolene using a Keith needle to avoid traumatizing the skin with forceps.    Above knee amputations (Callander technique): Does not cut across any muscle bellies but is purely dividing all muscular attachments through the tendinous insertions. It is similar to a through the knee amputation, but it involves dividing the femur immediately above the flare of the condyle with curved anterior and posterior fish mouth type flaps that again allow division without the trauma of muscular transection.   Postoperative care: knee immobilizer post-operatively after BKA to reduce risk of contractures, non–weight bearing on the stump until the fitting of a prosthesis 4 to 6 weeks after surgery, close follow up with vascular surgeon   Complications: primary healing fails in 20% to 30% of patients and approximately 1 in 5 patients undergoing BKA need a higher-level amputation due to wound problems   Top Asked Questions:   What ankle-brachial index is diagnostic of peripheral arterial disease?   Less than 0.9, severe PAD is less than 0.4. An ABI greater than 1.3 or 1.4 is considered non-diagnostic and further workup is indicated.   What is the Rutherford classification for peripheral arterial disease?   0- asymptomatic, 1- mild claudication, 2- moderate claudication, 3- severe claudication, 4- ischemic rest pain, 5- minor tissue loss, 6- major tissue loss    Which amputation level requires more energy to ambulate with a prosthesis?    Above knee amputations require 50-70% more energy than below knee amputations What are the compartments of the lower leg, and which major vessels and nerves are in each compartment?   Anterior- anterior tibial artery and vein, deep peroneal nerve Lateral- superficial peroneal nerve Deep posterior- posterior tibial artery and vein, peroneal artery and vein, tibial nerve Superficial posterior- mostly musculature

Python Bytes
#281 ohmyzsh + ohmyposh + mcfly + pls + nerdfonts = wow

Python Bytes

Play Episode Listen Later Apr 28, 2022 46:34


Leadership and the Environment
574: Frances Moore Lappé: Food, Democracy, and Taking Back Control of Our Choices

Leadership and the Environment

Play Episode Listen Later Apr 23, 2022 57:37


We spend most of our time talking about Frances's latest book, Daring Democracy. I couldn't help sharing how, decades after reading Diet for a Small Planet, I realized it was the first source that started me on the path to embracing and loving sustainability. I started by describing that path and my gratitude.If you haven't read the book, if you wonder why I'm so impassioned and feel so much joy where others are bogged down in shame, guilt, helplessness, facts, burden, and such, I recommend reading Diet for a Small Planet's fiftieth anniversary edition. You will connect deliciousness with sustainability, and fun, freedom, community, and other rewarding emotions. Regular listeners will also understand my origins better.Then we speak about democracy, especially in the US, and restoring it. We talk about Milton Friedman, the Kochs, Donald Trump, their peers, and their motivations; polarization; what to do about our situation. Underlying the facts, economics, and history are her optimism based in knowledge and history. She promotes accountability, especially of concentrated power. We look from a systemic perspective.We laughed a lot. If you consider sustainability a burden, I think you'll find this episode refreshing. And delicious. We can't change the past, but we can improve our world, which we're doing.The Small Planet Institute See acast.com/privacy for privacy and opt-out information.

Ninja Coaching Coast To Coast
What You Focus on Expands

Ninja Coaching Coast To Coast

Play Episode Listen Later Apr 14, 2022 32:22


Join Matt and Garrett in today's episode, where they talk about some tools to help you stay on track and focused on your path. Similar to their 'Gratitude and Action' episode from a few weeks ago, where they discussed how those components can help get you out of the complaining and scarcity mentalities, today's episode focuses on putting your dreams and visions out there, evaluating where you want to go, and staying on track to get there. Today's topic, while definitely inspired by that episode, is perfect for this time of year, as you wrap up the first quarter and head into the second quarter. Matt and Garrett spend time discussing how often, when people get busy, such habits as self-care, gratitude, and visualization affirmations take a back seat to the busyness. They revisit the notion that what you focus on expands, and they dive deep into how you can focus on the goal and on what you want to attract, versus focusing on what you think you lack. Find more great tips by joining the Ninja Selling Podcast group on Facebook at Ninja Selling Podcast Facebook, where you'll find a community of over 7500 Ninjas who share ideas, ask and answer questions, collaborate, and network. If you'd like to offer more direct feedback, leave a voicemail at 208-MY-NINJA. Check out Ninja Selling Events for upcoming installations and other events, and if you'd like personalized help in achieving your goals, visit Ninja Coaching to connect with one of our amazing coaches. Episode Highlights: How often should you revisit your business plan and mission statement? Two of Matt's stories about focus Tips for how to use and take advantage of vision boards Focus exactly on what you want and exactly the way you want it How to support your focus Empowering your vision Quotes: “Self-care, mentally and physically, goes out the window, typically, when we have a lot on our plate. It's like ‘Where can I find the time?'… But this is a great time to pull out your business plan.” “Curb the excuse monster, focus on ‘What are the actions that we can pull out of this?', and that's how you're going to be able to move forward.” “When you think about the vision board, we're not always exactly sure how those things are going to serve us. But if we don't focus on them, we don't even give them a chance to serve us, right?” “I think if we're going to focus on visioning and focusing on what you want right now, get really clear on what you want it to be, so that, as those opportunities show up around you, you know what path to take.” “We need to return to that focus… I've made a commitment to myself that focus is going to be maintained so that the vision can become a reality… There's a different level of energy and rejuvenation that comes into when you can freely focus on something without the scarcity coming into it.” “Anytime I see somebody put hyper-focus into a goal or a vision, a lot of times I watch them give the power away to coincidence… they don't take ownership, like ‘I just created that, or I just made that happen'… they very quickly go, ‘Yeah, but there were all these factors that went into it'.” “A lot of times, our negative stuff that we bring in is based on how we anticipate, how we perceive it's probably going to work.” “When you look at things to focus on in growing a business, it's very easy to get sucked into weird paths sometimes, of roadblocks and hurdles… it's very easy to get bogged down.” “Underlying your focus are supportive focus activities, right?” “I think ‘what you focus on expands' is a path toward the vision, to help the vision come through.” “We just have to be reminded. We have to set up systems in our world, like vision boards, that help remind us.” “If you don't have the good vision and good clarity around it, you can make decisions that don't give you the results that you want.” “Make a commitment to just figure out: What are some little things you can start to focus on?” Links: www.TheNinjaSellingPodcast.com Email us at TSW@TheNinjaSellingPodcast.com Leave a voicemail at (208) MY-NINJA Ninja Selling www.NinjaSelling.com @ninjasellingofficial Ninja Coaching: www.NinjaCoaching.com @ninja.coaching Ninja Events www.NinjaSelling.com/Events Garrett garrett@ninjacoaching.com @ninjaredding Matt matt@ninjacoaching.com @matthewjbonelli The Ninja Selling Podcast Facebook Group Gratitude and Action Episode

The Doctor's Farmacy with Mark Hyman, M.D.
3 Mistakes People Make When Trying To Heal Autoimmune Disease

The Doctor's Farmacy with Mark Hyman, M.D.

Play Episode Listen Later Apr 4, 2022 62:08


This episode is brought to you by Rupa Health, ButcherBox, and Pendulum. Autoimmune disease is, by far, the most widespread chronic health condition today, with a prevalence greater than heart disease, cancer, and diabetes combined. It is staggering! Sadly, however, conventional medicine is making numerous mistakes when it comes to treating patients with autoimmune disease by attempting to manage symptoms rather than resolve the root cause and heal the body. In this episode of my Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about what's really behind the rates of climbing autoimmune disease. We discuss environmental and dietary changes, reduction in quality of food, and much more—and then what we can do to heal. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, ButcherBox, and Pendulum. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. For a limited time, ButcherBox will send new subscribers 2 lbs of 100% grass-fed, grass-finished beef free in every box for the life of your subscription—plus an additional $10 off. To receive this offer, go to ButcherBox.com/farmacy. Pendulum is the first company to figure out how to harness the amazing benefits of Akkermansia in a probiotic capsule. To receive 20% off your first purchase of Pendulum's Akkermansia probiotic supplement, go to Pendulumlife.com and use code MARK20. In this episode, we discuss (audio version / Apple Subscriber version):Three mistakes people make in treating autoimmune disease (4:34 / 1:10) Underlying causes that are increasing rates of autoimmune disease (8:12 / 5:06) Why the Functional Medicine approach to health is unique (17:37 / 14:45) Toxins and how they contribute to autoimmune disease (18:35 / 15:40) Early detection of autoimmune activity (22:18 / 19:18) Functional Medicine testing to diagnose autoimmune disease (31:06 / 26:33) Questions from our community on scleroderma, Hashimoto's disease, emerging technologies, and more (39:33 / 34:44) Mentioned in this episode:Isabel Overcomes Autoimmune DiseaseThe UltraThyroid SolutionHow a Doctor Cured Her Autoimmune Disease with Functional Medicine Reversing Multiple Sclerosis and Autoimmune Disease with Functional Medicine See acast.com/privacy for privacy and opt-out information.