Podcasts about MSA

Avec Coach Castonguay, on revient sur notre marathon à Tuscon, où nos expériences ont été complètement opposées. On explique ce qu'on pense à mener au succès de Charles et à l'échec de PH. Magasinez dès maintenant chez Altitude Sports et profitez d'un rabais jusqu'à 20% sur votre première commande avec le code promo : UPIKA.Cliquez ici pour commander

Carla M. Nester, MD, MSA, FASN - 2025 Congress Highlights From Houston, Texas: Translating C3G and IC-MPGN Trials to Treatment in an Era of Complement Inhibition

Carla M. Nester, MD, MSA, FASN - 2025 Congress Highlights From Houston, Texas: Translating C3G and IC-MPGN Trials to Treatment in an Era of Complement Inhibition

Carla M. Nester, MD, MSA, FASN - 2025 Congress Highlights From Houston, Texas: Translating C3G and IC-MPGN Trials to Treatment in an Era of Complement Inhibition

Carla M. Nester, MD, MSA, FASN - 2025 Congress Highlights From Houston, Texas: Translating C3G and IC-MPGN Trials to Treatment in an Era of Complement Inhibition

In episode 220, host Galit Friedlander and guest Chad Geiger (dance agent at The Movement Talent Agency) pull back the curtain on what representation really looks like from the agency side and what dancers often misunderstand about it. We talk about essential pieces of a sustainable dance career: communication, contracts, headshots and resumes that actually serve you, and how your choices off the floor impact your opportunities just as much as your training on it. Chad shares insight on navigating direct bookings, building trust with your team, and why “doing the basics well” is still one of the biggest differentiators in today's industry. Follow Galit: Instagram – https://www.instagram.com/gogalit Website – https://www.gogalit.com/ Fit From Home – https://galit-s-school-0397.thinkific.com/courses/fit-from-home You can connect with Chad Geiger on https://www.instagram.com/chad_geiger Listen to DanceSpeak on Apple Podcasts and Spotify.

Cette semaine on reçoit Anabelle Guay qui travaille actuellement sur son doctorat en lien avec la psychologie sportive. Elle nous explique comment améliorer sont discours interne afin d'optimiser ses performances. Elle revient aussi sur sa récente expédition au Mont Blanc.Magasinez dès maintenant chez Altitude Sports et profitez d'un rabais jusqu'à 20% sur votre première commande avec le code promo : UPIKA.Cliquez ici pour commander

In this episode of The MHP Broker's Tips and Tricks Closing Cocktail podcast, Maxwell Baker, president of The Mobile Home Park Broker, interviewed The MHP Broker Eric Wanck about his Shell Way Mobile Home Park transaction near Knoxville. As with every Tips and Tricks podcast episode, this one is brought to you by The MHP Broker's proprietary Community Price Maximizer. Use this four-step system to get the highest price possible for your mobile home park or RV community when you sell it through The MHP Broker. Guaranteed. Call Max for details. Here are the Show Highlights This deal was a smaller transaction than what the team typically takes to market, and with the park needing a heavy lift, Eric wasn't sure what to expect. But within just two weeks of launching, multiple offers came in over asking price, driven by the property's location, upside, and city utilities. (Max & Eric, 01:17) The park sat outside the Knoxville MSA but still drew strong interest due to its proximity to the Gatlinburg area and its overall desirability. Investors saw strong value despite the park's size and condition. (Eric, 01:51) There was no fallout after the bidding process. The first buyer who went under contract made it all the way to closing thanks to proper buyer qualification and a smooth due diligence period. (Eric, 02:24) The deal ultimately closed all cash, prompting Max's callback that it closed "caaaash money, y'all," reflecting The MHP Broker's ability to attract serious, ready-to-close buyers. (Max, 03:02) Investor demand is so strong in this Knoxville/Gatlinburg corridor that Eric joked he wished he could find "six more" parks just like it for eager buyers. (Eric, 03:49) From launch to close, the deal moved quickly—closing in just 45 days—showing the surprising strength of the market's response. (Eric, 04:08) Max wrapped up the episode by highlighting The MHP Broker's 86% first-to-contract close ratio, driven by impeccable upfront due diligence. "Problems don't kill deals; surprises do." (Max, 04:59) Power Quotes "This deal… was surprisingly really, really sexy." (Max, 0:22) "Within two weeks we had multiple offers above asking… location and upside were everything." (Eric, 01:52) "The first buyer closed—smooth as butter." (Eric, 02:24) "It closed straight up… 'caaaash money, y'all." (Max, 03:02) "I just wish I could find six more of these up there." (Eric, 03:49) "We get deals sold—fast, the first time." (Max, 04:59) "Problems don't kill deals. Surprises do." (Max, 04:59) 00:00 Hello and welcome to the Mobile Home Park Brokers' tips and tricks. This is the podcast where we talk about mobile home park investing because that's what we've been involved in for the last decade. Let's dive into today's episode. Here is your host, Maxwell Baker. 00:22 Maxwell Baker Hey y'all. Welcome to another beautiful episode of the Mobile Home Park Brokers Tips and tricks podcast. As always, this episode is brought to you by the Community Price Maximizer. No pun intended there, it just actually happened to be named that. It is your proprietary system that will guarantee you a higher price when you exclusively list with us. Call us (678) 932-0200 and we will get you that price that you have dreamed of. Especially right now. The market is booming here at the end of 2025. But we are here to celebrate that Eric Wank just closed this deal, Shell Way, right outside Knoxville. Eric, welcome to the show. Congrats again on a closing, but damn, dude, this deal like was surprisingly real, really, really sexy. You had a tonne of people really getting into this deal, right? 01:17 Eric Wanck Yeah, yeah, no, thank you. One of my favourite things to get on here and talk about closing, closing property, and you're right, you know, this was an interesting deal from the start, a little bit of a smaller transaction size than we typically take to market repeat client though on our end and we said, hey, sure, no problem, we'll take this on for you and it was outside the Knoxville MSA probably certainly within a couple hour drive of the Gatlinburg area, very beautiful area of the country, and to be honest, taking this out to market, I wasn't sure what to expect. 01:51 Maxwell Baker Yeah 01:52 Eric Wanck Just given how much of a heavy lift this park needed and the size of the park, but within, I would say within 2 weeks we had multiple offers above asking price… 02:06 Maxwell Baker Yeah 02:07 Eric Wanck …which just showed that location, upside, two real big things right there, and it was on city water and sewer, which of course always helps when investors are looking at parks. 02:20 Maxwell Baker Yeah, man, tell us about the first time you put it under contract, we closed on it, right? 02:25 Eric Wanck That's right 02:24 Maxwell Baker There wasn't a fallout or anything? 02:26 Eric Wanck Yeah, no, we, we went through the bidding process with the highest and best, and, and those folks ended up closing. So,  very smooth in that aspect, and that's what we want to see is qualifying, who we're bringing to the table and, and making sure that they get to the finish line the first time so we're not having to do it over and over but yeah, no, it was very smooth. 02:45 Maxwell Baker Yeah, man and it closed caaaash money. I remember some of these guys that I've worked with in the past. I think it was Frank Roth that mentioned it.  He's like this guy in this mobile home park that he owned, said that, he would sell him his mobile home for 4000 caaash money. 03:02 Eric Wanck (laughs) 03:03 Maxwell Baker And, this deal closed, to quote that guy, caaaash money, y'all. So, if you need; if you've got a deal and you're looking for that cash money. That's, that's what happened here. Eric was able to pull, to pull from another podcast we just did, another rabbit out of the hat. We have a whole stable of rabbits here, because of all the magicians we have, AKA Eric Wank, pulling rabbits out of the hat and this deal was one of those. I mean, he got it done all cash, got it. Priced competitively, had it bid above market what we took it out, yeah, the seller was happy! Buyer was happy! Dude, any closing comments on this? 03:49 Eric Wanck Hey, I just wish I could find 6 more up there and I; 03:52 Maxwell Baker Oh, I know, seriously, right? (laughs) 03:54 Eric Wanck Probably some people listening that are, that are saying, yeah, no problem, Eric, send them my way, and I'm happy to do so as well, you know, that's, we are targeting a lot of these MSA areas, and that is obviously a pretty hot one given the activity we had on it, so. 04:07 Maxwell Baker Yeah 04:08 Eric Wanck But yeah, no, it's a very surprising deal from the, the onset, putting it to market. I really, I thought we were gonna be sitting, to be honest with you, but here we go, 45 days later, we were closed. 04:20 Maxwell Baker Let's go, baby. All right, y'all. Eric, thanks for jumping on the podcast with us here. Congrats on the closing! and y'all give him a call. He is the All-Star magician so far this year, top producer. You can reach him at (678) 932-0200. You've got deals, you've got beautiful deals, you got hairy deals, you've got development deals. We are the organisation that will get it sold and usually we get it sold really quickly and then the first time we don't fall. Most of our competition falls in and out of contract 10 times before they actually sell your park. 04:59 We have a high first to contract close ratio of 86%. That means when we put your park under contract, 86% of the time with the first buyer that we bring you, when you exclusively list with us, is going to close on your deal. No other competitors can, can tout that. We are the biggest firm that can do that, and Eric is a shining example here that was able to do that is because we do impeccable due diligence upfront on all of our exclusive listings. That way, you know, problems don't kill deals, but surprises do and we figure out what all The variables are so that way when we do put it on a contract, we've already got answers to all the problems. So, give us a call 678-932-0200. Happy to chat. Happy to talk high level. Ask for Eric Wanck. He is the man here at the firm and Eric, thanks for being here, buddy. Let's keep moving forward!

December 2025's Patch Tuesday brought major shifts, but the real action is in Microsoft's pricing, privacy battles, and the arms race to control AI-enabled browsers. Plus, Paul recommends Tiny11 Builder for a clean install, or Win11Debloat for an existing install. Then, Rufus to create installation media without the forced Microsoft account (MSA) sign-in or hardware requirement checks. Use MSEdgeDirect to use the default web browser for stories from Widgets, web-based search results, etc. And ExplorerPatcher can fix the performance and reliability issues in File Explorer. It's the final Patch Tuesday of 2025 Major dark mode updates (with a fix for the "flashbang" problem) AI Agent in Settings, Click to Do, Windows Studio Effects, and Search improvements for Copilot+ PCs Many other improvements: FSE, Share, Settings, Widgets, more More Windows 11 New 25H2 preview build on Beta/Dev adds MCP public preview, Quick Machine Recovery auto-enabled, Unified Update Orchestration Platform, Windows MIDI services Microsoft 365 Microsoft 365 is getting a lot more expensive in mid-2026. You didn't think all those free AI updates were free, did you? AI Paul has been talking about "programmatic" apps and services because he wasn't sure of a term for this type of interaction. But there is a term for this: Semantic. As in semantic web. And there you go Microsoft one of 1,000 companies partnering on Agentic AI Foundation because you're getting agents whether they work or not Gartner says NO to AI web browsers The New York Times is suing Perplexity for all the obvious reasons After a big win in the legal battle with OpenAI Opera for Android gets a big AI update Google Workspace Studio brings code-free agent creation to business users - automation is a solid AI use case Xbox Xbox Series X|S notably absent during Black Friday sales Call of Duty won't repeat the mistakes of the past anymore since it didn't work out twice now MS Flight Simulator 2024 is now available on PS5 Red Dead Redemption comes to mobile for the first time, free with a Netflix account Tips & Picks Tip and app(s) of the week: De-enshittify Windows 11 RunAs Radio this week: Incident Management and the Crowdstrike Event with Liam Westley Brown liquor pick of the week: Old Farm Pennsylvania Straight Rye Whiskey Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: 1password.com/windowsweekly auraframes.com/ink helixsleep.com/windows ventionteams.com/twit

December 2025's Patch Tuesday brought major shifts, but the real action is in Microsoft's pricing, privacy battles, and the arms race to control AI-enabled browsers. Plus, Paul recommends Tiny11 Builder for a clean install, or Win11Debloat for an existing install. Then, Rufus to create installation media without the forced Microsoft account (MSA) sign-in or hardware requirement checks. Use MSEdgeDirect to use the default web browser for stories from Widgets, web-based search results, etc. And ExplorerPatcher can fix the performance and reliability issues in File Explorer. It's the final Patch Tuesday of 2025 Major dark mode updates (with a fix for the "flashbang" problem) AI Agent in Settings, Click to Do, Windows Studio Effects, and Search improvements for Copilot+ PCs Many other improvements: FSE, Share, Settings, Widgets, more More Windows 11 New 25H2 preview build on Beta/Dev adds MCP public preview, Quick Machine Recovery auto-enabled, Unified Update Orchestration Platform, Windows MIDI services Microsoft 365 Microsoft 365 is getting a lot more expensive in mid-2026. You didn't think all those free AI updates were free, did you? AI Paul has been talking about "programmatic" apps and services because he wasn't sure of a term for this type of interaction. But there is a term for this: Semantic. As in semantic web. And there you go Microsoft one of 1,000 companies partnering on Agentic AI Foundation because you're getting agents whether they work or not Gartner says NO to AI web browsers The New York Times is suing Perplexity for all the obvious reasons After a big win in the legal battle with OpenAI Opera for Android gets a big AI update Google Workspace Studio brings code-free agent creation to business users - automation is a solid AI use case Xbox Xbox Series X|S notably absent during Black Friday sales Call of Duty won't repeat the mistakes of the past anymore since it didn't work out twice now MS Flight Simulator 2024 is now available on PS5 Red Dead Redemption comes to mobile for the first time, free with a Netflix account Tips & Picks Tip and app(s) of the week: De-enshittify Windows 11 RunAs Radio this week: Incident Management and the Crowdstrike Event with Liam Westley Brown liquor pick of the week: Old Farm Pennsylvania Straight Rye Whiskey Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: 1password.com/windowsweekly auraframes.com/ink helixsleep.com/windows ventionteams.com/twit

December 2025's Patch Tuesday brought major shifts, but the real action is in Microsoft's pricing, privacy battles, and the arms race to control AI-enabled browsers. Plus, Paul recommends Tiny11 Builder for a clean install, or Win11Debloat for an existing install. Then, Rufus to create installation media without the forced Microsoft account (MSA) sign-in or hardware requirement checks. Use MSEdgeDirect to use the default web browser for stories from Widgets, web-based search results, etc. And ExplorerPatcher can fix the performance and reliability issues in File Explorer. It's the final Patch Tuesday of 2025 Major dark mode updates (with a fix for the "flashbang" problem) AI Agent in Settings, Click to Do, Windows Studio Effects, and Search improvements for Copilot+ PCs Many other improvements: FSE, Share, Settings, Widgets, more More Windows 11 New 25H2 preview build on Beta/Dev adds MCP public preview, Quick Machine Recovery auto-enabled, Unified Update Orchestration Platform, Windows MIDI services Microsoft 365 Microsoft 365 is getting a lot more expensive in mid-2026. You didn't think all those free AI updates were free, did you? AI Paul has been talking about "programmatic" apps and services because he wasn't sure of a term for this type of interaction. But there is a term for this: Semantic. As in semantic web. And there you go Microsoft one of 1,000 companies partnering on Agentic AI Foundation because you're getting agents whether they work or not Gartner says NO to AI web browsers The New York Times is suing Perplexity for all the obvious reasons After a big win in the legal battle with OpenAI Opera for Android gets a big AI update Google Workspace Studio brings code-free agent creation to business users - automation is a solid AI use case Xbox Xbox Series X|S notably absent during Black Friday sales Call of Duty won't repeat the mistakes of the past anymore since it didn't work out twice now MS Flight Simulator 2024 is now available on PS5 Red Dead Redemption comes to mobile for the first time, free with a Netflix account Tips & Picks Tip and app(s) of the week: De-enshittify Windows 11 RunAs Radio this week: Incident Management and the Crowdstrike Event with Liam Westley Brown liquor pick of the week: Old Farm Pennsylvania Straight Rye Whiskey Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: 1password.com/windowsweekly auraframes.com/ink helixsleep.com/windows ventionteams.com/twit

December 2025's Patch Tuesday brought major shifts, but the real action is in Microsoft's pricing, privacy battles, and the arms race to control AI-enabled browsers. Plus, Paul recommends Tiny11 Builder for a clean install, or Win11Debloat for an existing install. Then, Rufus to create installation media without the forced Microsoft account (MSA) sign-in or hardware requirement checks. Use MSEdgeDirect to use the default web browser for stories from Widgets, web-based search results, etc. And ExplorerPatcher can fix the performance and reliability issues in File Explorer. It's the final Patch Tuesday of 2025 Major dark mode updates (with a fix for the "flashbang" problem) AI Agent in Settings, Click to Do, Windows Studio Effects, and Search improvements for Copilot+ PCs Many other improvements: FSE, Share, Settings, Widgets, more More Windows 11 New 25H2 preview build on Beta/Dev adds MCP public preview, Quick Machine Recovery auto-enabled, Unified Update Orchestration Platform, Windows MIDI services Microsoft 365 Microsoft 365 is getting a lot more expensive in mid-2026. You didn't think all those free AI updates were free, did you? AI Paul has been talking about "programmatic" apps and services because he wasn't sure of a term for this type of interaction. But there is a term for this: Semantic. As in semantic web. And there you go Microsoft one of 1,000 companies partnering on Agentic AI Foundation because you're getting agents whether they work or not Gartner says NO to AI web browsers The New York Times is suing Perplexity for all the obvious reasons After a big win in the legal battle with OpenAI Opera for Android gets a big AI update Google Workspace Studio brings code-free agent creation to business users - automation is a solid AI use case Xbox Xbox Series X|S notably absent during Black Friday sales Call of Duty won't repeat the mistakes of the past anymore since it didn't work out twice now MS Flight Simulator 2024 is now available on PS5 Red Dead Redemption comes to mobile for the first time, free with a Netflix account Tips & Picks Tip and app(s) of the week: De-enshittify Windows 11 RunAs Radio this week: Incident Management and the Crowdstrike Event with Liam Westley Brown liquor pick of the week: Old Farm Pennsylvania Straight Rye Whiskey Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: 1password.com/windowsweekly auraframes.com/ink helixsleep.com/windows ventionteams.com/twit

December 2025's Patch Tuesday brought major shifts, but the real action is in Microsoft's pricing, privacy battles, and the arms race to control AI-enabled browsers. Plus, Paul recommends Tiny11 Builder for a clean install, or Win11Debloat for an existing install. Then, Rufus to create installation media without the forced Microsoft account (MSA) sign-in or hardware requirement checks. Use MSEdgeDirect to use the default web browser for stories from Widgets, web-based search results, etc. And ExplorerPatcher can fix the performance and reliability issues in File Explorer. It's the final Patch Tuesday of 2025 Major dark mode updates (with a fix for the "flashbang" problem) AI Agent in Settings, Click to Do, Windows Studio Effects, and Search improvements for Copilot+ PCs Many other improvements: FSE, Share, Settings, Widgets, more More Windows 11 New 25H2 preview build on Beta/Dev adds MCP public preview, Quick Machine Recovery auto-enabled, Unified Update Orchestration Platform, Windows MIDI services Microsoft 365 Microsoft 365 is getting a lot more expensive in mid-2026. You didn't think all those free AI updates were free, did you? AI Paul has been talking about "programmatic" apps and services because he wasn't sure of a term for this type of interaction. But there is a term for this: Semantic. As in semantic web. And there you go Microsoft one of 1,000 companies partnering on Agentic AI Foundation because you're getting agents whether they work or not Gartner says NO to AI web browsers The New York Times is suing Perplexity for all the obvious reasons After a big win in the legal battle with OpenAI Opera for Android gets a big AI update Google Workspace Studio brings code-free agent creation to business users - automation is a solid AI use case Xbox Xbox Series X|S notably absent during Black Friday sales Call of Duty won't repeat the mistakes of the past anymore since it didn't work out twice now MS Flight Simulator 2024 is now available on PS5 Red Dead Redemption comes to mobile for the first time, free with a Netflix account Tips & Picks Tip and app(s) of the week: De-enshittify Windows 11 RunAs Radio this week: Incident Management and the Crowdstrike Event with Liam Westley Brown liquor pick of the week: Old Farm Pennsylvania Straight Rye Whiskey Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: 1password.com/windowsweekly auraframes.com/ink helixsleep.com/windows ventionteams.com/twit

December 2025's Patch Tuesday brought major shifts, but the real action is in Microsoft's pricing, privacy battles, and the arms race to control AI-enabled browsers. Plus, Paul recommends Tiny11 Builder for a clean install, or Win11Debloat for an existing install. Then, Rufus to create installation media without the forced Microsoft account (MSA) sign-in or hardware requirement checks. Use MSEdgeDirect to use the default web browser for stories from Widgets, web-based search results, etc. And ExplorerPatcher can fix the performance and reliability issues in File Explorer. It's the final Patch Tuesday of 2025 Major dark mode updates (with a fix for the "flashbang" problem) AI Agent in Settings, Click to Do, Windows Studio Effects, and Search improvements for Copilot+ PCs Many other improvements: FSE, Share, Settings, Widgets, more More Windows 11 New 25H2 preview build on Beta/Dev adds MCP public preview, Quick Machine Recovery auto-enabled, Unified Update Orchestration Platform, Windows MIDI services Microsoft 365 Microsoft 365 is getting a lot more expensive in mid-2026. You didn't think all those free AI updates were free, did you? AI Paul has been talking about "programmatic" apps and services because he wasn't sure of a term for this type of interaction. But there is a term for this: Semantic. As in semantic web. And there you go Microsoft one of 1,000 companies partnering on Agentic AI Foundation because you're getting agents whether they work or not Gartner says NO to AI web browsers The New York Times is suing Perplexity for all the obvious reasons After a big win in the legal battle with OpenAI Opera for Android gets a big AI update Google Workspace Studio brings code-free agent creation to business users - automation is a solid AI use case Xbox Xbox Series X|S notably absent during Black Friday sales Call of Duty won't repeat the mistakes of the past anymore since it didn't work out twice now MS Flight Simulator 2024 is now available on PS5 Red Dead Redemption comes to mobile for the first time, free with a Netflix account Tips & Picks Tip and app(s) of the week: De-enshittify Windows 11 RunAs Radio this week: Incident Management and the Crowdstrike Event with Liam Westley Brown liquor pick of the week: Old Farm Pennsylvania Straight Rye Whiskey Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: 1password.com/windowsweekly auraframes.com/ink helixsleep.com/windows ventionteams.com/twit

Magasinez dès maintenant chez Altitude Sports et profitez d'un rabais jusqu'à 20% sur votre première commande avec le code promo : UPIKA.Cliquez ici pour commander

Steeve , Shawn et Yoan font un retour sur leur saison 2025, voyages dans l'ouest Canadien et aux US, la finale de la WC au MSA etc.. Et pour le volet Geek Club, on parle de nos expériences avec certains équipements tel que les pneus thick slick, switch grade aenomaly, Thru tune, Damper X2, O'chain incluant nos prédiction suite à son intégration chez Sram et finalement l'arrivé des vélos avec roues de 32po.Bonne écoute.

Cette semaine, je reçois l'étoile montante du Trail québécois: Xavier St-Cyr. Il nous raconte sa préparation et ses victoires dans les deux plus grosses courses au Québec.Magasinez dès maintenant chez Altitude Sports et profitez d'un rabais jusqu'à 20% sur votre première commande avec le code promo : UPIKA.Cliquez ici pour commander

Interview Date:Episode Summary:MSA New York's Talent Director Bre Traver breaks down exactly how dancers get on an agent's radar and build sustainable careers. From her path from dancer to agent, to what MSA looks for in reels, headshots, and Instagrams, Bre shares practical, no-fluff guidance on submissions, onboarding, and being an ideal client. She contrasts the NYC vs. LA markets (live stage, Broadway, tours, award shows), outlines big client don'ts, and explains how agents scout in class, at shows, and online. The lively Q&A hits trends, triple-threat training, youth work, self-tapes vs. in-person calls, and why persistence, professionalism, and clear goals separate dancers who book “the big jobs.”Shownotes:(0:00) – Welcome & intro to MSA and Bre's NYC leadership (11:28) – Bre's journey: dancer to MSA Talent Director(20:24) – Inside MSA NYC: Broadway, tours, TV, and more (24:53) – How dancers get signed and scouted by agents (28:14) – Social media tips: Instagram presence that books work (32:23) – Onboarding goals: materials, availability, and communication(35:56) – NYC vs LA markets: knowing where you belong (39:10) – Professionalism tips: biggest audition and booking don'ts(44:10) – How agents scout in class and online presence matters (51:12) – Q&A takeaways: training, self-tapes, visas, and persistenceBiography:Bre Traver joined McDonald Selznick Associates East Coast division in 2007. She worked through the ranks as an assistant to Jr. Agent, to Franchised Sr. Agent, to Director of the Talent Department to now Equity Partner in the company. Prior to agenting, Bre grew up as a dancer and received a BFA from University at Buffalo. Bre is still serving as a lead agent for MSA's NY talent roster. Over the years she has had the pleasure of booking clients on national commercials (APPLE, Advil PM, Pepsi), feature films (Best of The Best, West Side Story, In The Heights, 13, Tick Tick Boom), television (SNL, Law & Order, Pose, Maisel, Étoile, GMA, The Tonight Show, Last Week Tonight), award shows (MTV VMAs, BET Awards, Super Bowl Halftime), national tours (Hamilton, Wicked, Moulin Rogue, MJ, Hell's Kitchen, Beetlejuice, Some Like It Hot, The Notebook, Mean Girls, Chicago), and live work (Corporate industrials, New York Fashion Week, The Met Gala). Bre is proud to work on behalf of such an established roster of talent and enjoys keeping her finger on the pulse of our ever-changing industry!Connect on Social Media:Instagram: https://www.instagram.com/breezyotoole/?hl=enWebsite: www.msaagency.com

In this episode, Galit sits down with creator and educator Jason Pickett for a real conversation about the shifts happening in today's dance world. Jason shares his path from Utah's freestyle community to building a career outside the traditional LA route, and the mindset behind choosing what actually feels right. They dig into the responsibilities of teachers and influencers online, the short-sightedness that's causing dance studios and conventions business, and a shift in what dancers want to do professionally. Jason and Galit also explore whether competitions are watering down dance, how COVID changed the mentality of young dancers, and why the best teachers don't rely on the “combo.” This episode pulls back the curtain on connecting the generations, talent development, and what it really means to create good dancers - not just good perfectionists. Follow Galit: Instagram - https://www.instagram.com/gogalit Website - https://www.gogalit.com/ On-Demand Fitness Courses - https://galit-s-school-0397.thinkific.com/collections Follow Jason Pickett: Instagram - https://www.instagram.com/heyitspickett/ Jason's Website - https://nsadance.com/

Je reçois Marc-Antoine Senneville, coureur et entraîneur, qui tentera sa chance pour battre le record québécois sur marathon détenu par Alain Bordeleau qui date de 1984 dans quelques semaines au marathon de Valence.Magasinez dès maintenant chez Altitude Sports et profitez d'un rabais jusqu'à 20% sur votre première commande avec le code promo : UPIKA.Cliquez ici pour commander

For more than 30 years, MSA National has been transforming the loan documentation process – partnering with some of Australia's largest lenders to make settlements faster, smoother, and more seamless for brokers and their clients. In this episode of In Focus, we speak with MSA National founder and CEO Sam Makhoul and Sergio Delvescovo, national sales manager for the broker channel and former head of lending operations at ING Australia. They discuss how MSA's partnerships have helped drive efficiency, lift broker satisfaction scores, and reduce ING Australia's average settlement time from 24 days to just 10–12 days. Tune in to discover: Three things that brokers can do for faster settlements. How MSA's products have transformed the broker and customer experience. The borrower story that made Makhoul cry and how that shaped the MSA culture. And much more!

Cette semaine, je reçois Victor Larocque qui nous raconte sa course au 100miles Chihuahua By UTMB. On reçoit ensuite son coach, Charles Castonguay pour décortiquer son programme d'entraînement l'ayant mené à cette performance.Magasinez dès maintenant chez Altitude Sports et profitez d'un rabais jusqu'à 20% sur votre première commande avec le code promo : UPIKA.Cliquez ici pour commander

Mới đây bác sĩ đa khoa Michael Dũng Cao, đã nói về bệnh đa xơ xứng hay Multiple Sclerosis hay MS. Chúng ta đã biết về nguyên nhân, triệu chứng và khác biệt với chứng đột quỵ hay tai biến mạch máu não, cũng như khác với MSA hay chứng teo đa hệ thống. Hôm nay Bác sĩ Michael Dũng tiếp tục nói về những tiến triển, trong nghiên cứu và điều trị chứng bệnh mạn tính nầy.

I had a SASS listener reach out to me a few months ago via email. It was a short email, but it sure got my attention. The writer, Diane, told me that she had been listening to SASS for a while, and that she was very appreciative of the show, as she is a survivor of military sexual assault (MSA) from almost 50 years ago. She also told me she had sent me a large envelope of important information about her case…certified, return receipt. That'll peak you're curiosity! I did get a large envelope a few days later. It was a pretty full, 9x12 , mailing envelope, full of documents—letters, law enforcement reports, a narrative of Diane's story—enough to keep me reading for about an hour. And what I read was both horrific and miserable information, but frustrating and compelling at the same time. It was a compilation of most of the work that Diane had been compiling for the past almost 50 years in order to try to get the Army to bring a retired physician back into active duty for the purpose of having him court-martialed. Can you imagine how frustrating it must feel to have your case investigated by one of this country's foremost criminal investigation agencies, have the investigation result in being substantiated, sue the perpetrator civilly, and win, and then to have the Army's prosecutors refuse to prosecute your case…for no particular reason other than to save face for the Army because to court-martial a retired colonel, doctor, from the Army would be embarrassing. Yeah…that's what happened. It's asinine; you're gonna want to hear the story from Diane herself. So listen to this episode. Then, share it with everyone you know. Because it's that important! An important side note: if you're finding value in this show and these amazing episodes, please take a moment to leave a 5-star rating on your podcast platform. AND, follow SexualAssaultSurvivorStories on Instagram, then, please send me a note of support. I can't tell you how much your emails mean to me—they fuel my passion to keep this podcast going. And if you're a victim or survivor and are ready to tell your story in order to help yourself or someone else heal, let me know, and we can start a conversation about the possibility of you being on the show.  Here's my email address: dave@sasstories.com  Thank you to all of you who have reached out to me already. Just provide me with a phone number where I can reach back out to you…because I like to talk to people who are interested in guesting. And please keep those emails and texts coming…I truly look forward to hearing from you! Here are some critically important links that I hope you'll take the time to explore, and where a contribution is requested, please consider doing so!—Thank you!! https://soulwisesolutions.com https://safeinharmsway.org https://sironahealing.com/ https://www.whattheydontsay.com https://www.survivor-school.com/?ref=DAVEMARKEL www.arcigrey.com  https://podcasts.apple.com/us/podcast/invisible-no-more-lady-veterans-stories-of-military/id1754061590 https://startbybelieving.org https://evawintl.org/ As mentioned, and emphasized, it's time to Normalize the Conversation.™ And please remember to Start by Believing…because we all know someone whose life has been impacted by rape or sexual assault. Thank you for tuning in.

Cette semaine, je m'intéresse à un nouveau sport d'endurance; le Hyrox. Je reçois donc deux experts et un débutant pour faire une table ronde sur cette discipline qui allie force et endurance.Magasinez dès maintenant chez Altitude Sports et profitez d'un rabais jusqu'à 20% sur votre première commande avec le code promo : UPIKA.Cliquez ici pour commander

Dr. Alessandra Fanciulli discusses how the MDS criteria for the diagnosis of MSA has made an impact on the field, the status of biomarker research, and optimal targets for disease-modifying trials for MSA.

Interview Date: September 21st, 2025Episode Summary:In this inspiring conversation, Menina Fortunato sits down with Julie McDonald, the trailblazing co-founder of MSA Agency and the first dance agent in history. Julie shares her incredible journey from professional dancer to industry visionary—representing some of the biggest names in choreography and performance.She reflects on the evolution of the commercial dance world, the importance of professionalism and preparation, and what truly sets apart dancers who build lasting careers. Julie offers invaluable advice on networking, auditions, and why knowing your dance history—from Bob Fosse to Jerome Robbins—is essential for any serious artist.From agency insight to mentorship, this episode is filled with stories, wisdom, and warmth from a woman who changed the industry for dancers everywhere. Julie also shares exciting news about being honored with the Trailblazer Award at Gala of the Stars—a full-circle moment for one of dance's greatest advocates.This episode is perfect for dancers, teachers, and aspiring professionals who want to understand the business behind dance, the art of longevity, and the power of curiosity and gratitude in shaping a meaningful career.Shownotes:(0:00) – Welcome & intro to Julie McDonald and her legacy (3:15) – Julie's start as a dancer & transition into agency life (7:40) – Founding MSA: creating the first dance agency in the world(12:25) – Representing choreographers, dancers & industry icons(22:10) – What makes a dancer stand out to an agent(35:05) – How the dance industry evolved through the decades (50:12) – Advice: professionalism, mindset, and consistency (1:13:05) – Julie's message: know your dance history & icons (1:16:16) – Gala of the Stars — Julie honored with Trailblazer Award(1:16:57) – Closing: gratitude, selfies, and inspiration for young dancersBiography:Julie McDonald is the visionary co-owner of McDonald Selznick Associates (MSA) and a trailblazer in dance and choreography representation. In 1985, she launched the first talent agency devoted exclusively to dance, setting a new standard for advocacy, professionalism, and artistic excellence in the industry.From the outset, Julie championed fair terms and improved working conditions for dancers and choreographers, tirelessly promoting the visibility and integrity of commercial dance. In 2000, she joined forces with Tony Selznick to found MSA, which today represents a roster of award‑winning talent. Her clients have earned Emmy, Tony, MTV, and MTV Awards—while leading the creative teams behind Broadway hits, Las Vegas spectaculars, high‑profile films, television dramas, sitcoms, and major awards shows (Emmy, Grammy, Oscar).A dedicated collaborator and industry visionary, Julie co‑created the American Choreography Awards (1994–2004), celebrating excellence in dance across media. Her pioneering work has been recognized with Lifetime Achievement Awards from both the Choreographers Carnival and McCallum's Choreography Festival.Through her ongoing projects and continued leadership at MSA, Julie McDonald remains a powerful force in shaping the future of dance, honoring its past, and empowering the artists who bring it to life.Connect on Social Media:Instagram- https://www.instagram.com/juliemcdonaldmsa/

Cette semaine, Karel Cadoret nous raconte son aventure au 100KM de l'Ultra-Trail du Fjord du Saguenay. C'était une fin de semaine extrêmement chaude durant laquelle plus de la moitié du peloton n'a pas terminé!Magasinez dès maintenant chez Altitude Sports et profitez d'un rabais jusqu'à 20% sur votre première commande avec le code promo : UPIKA.Cliquez ici pour commander

MSA, what a way to end the season. Grueling and daunting, it's a track that other venues will forever be compared against. It feels wrong that this could be the last World Cup at Mont Sainte Anne for a long time (if not ever). At least the final send-off race was one to remember. For our crew, it was memorable because our guy Dak, against a lot of odds, slotted himself into 4th place less than a year after a life-altering injury. We couldn't be prouder. In this episode, we chat about Dak's program (or lack thereof) going into the off-season, Jackson doing Jackson things to take the overall title, the current rider pool being so deep, tire sealant tips, Rampage thoughts, and what type of content is even engaging these days. Thanks for listening and supporting the podcast this season! 

In episode 218, host Galit Friedlander and guest Ben “BTEK” Chung (Kinjaz co-founder, Jabbawockeez, America's Best Dance Crew, and entrepreneur/consultant) dig into what happens when you refuse to take the conventional route. Ben shares how he went from production work at MTV to dancing full-time, creating his own lane instead of following someone else's path. We talk about best communication practices, navigating contracts with confidence, and redefining success as your career and even priorities change. Ben opens up about mindset, faith, and finding growth in life's detours, plus what it really takes to stay sharp and inspired over the long game. Follow Galit: Instagram - https://www.instagram.com/gogalit Website - https://www.gogalit.com/ On-Demand Fitness Courses - https://galit-s-school-0397.thinkific.com/collections Follow Ben Chung: Instagram - https://www.instagram.com/btek_benchung Werkflow - https://www.werkflow.us/

The 3 Everyday Habits That Win Trust Sales rises or falls on trust. As of 2025—post-pandemic, hybrid, and time-poor—buyers have less patience for fluffy rapport and more appetite for authentic, repeatable behaviours. This guide turns three classic human-relations principles into practical sales moves you can use today: be genuinely interested, smile first, and use people's names naturally. What's the fastest way to build trust with time-poor buyers in 2025? Lead with curiosity, not a pitch. Ask about their context before your product, and mirror back what you heard in concrete terms (KPIs, deadlines, constraints). This converts a transactional meeting into a partnership from minute one. In Japan, the US, and Europe alike, executives are bandwidth-constrained; they remember the seller who reduces cognitive load. In enterprise deals, curiosity surfaces hidden stakeholders and post-purchase risks. In SMEs and startups, it reveals cash-flow windows and procurement shortcuts. Curiosity isn't manipulation; buyers detect feigned interest instantly. Done right, it creates common ground that makes every later ask easier. Start every meeting with one “business-human” question (e.g., “What must be true by quarter-end for this to be a win?”). Mini-summary: Curiosity first → faster trust → smoother deals. Do now: Prepare three context questions per persona. How do I show genuine interest without going off-topic? Be human, but keep it business-linked. Tie personal context to business impact; keep it relevant, short, and anchored in their role, industry, and timeline. Ask about post-purchase adoption (“What would success look like for your users in the first 30 days?”), operational realities (e.g., Japan-specific compliance), and leadership pressures (“What will your CFO scrutinise most this quarter?”). Compare contexts—APAC vs EU privacy, B2B vs consumer rollout, startup urgency vs multinational governance. Document what you learn and open the next meeting by recapping their words—snippet-ready proof you listened. Mini-summary: Human questions, business purpose. Do now: Build a one-page “interest map” per account. Does smiling still matter in serious, high-stakes meetings? Smile first to set the social temperature, then match the room. Under deadline pressure, many sellers present a tense “serious face” that raises defensiveness. A genuine, early smile lowers friction and signals “I'm safe to talk to,” especially in first meetings or escalations. In Japan's formal settings, a measured smile plus a slight nod communicates respect and openness; in the US, a warmer smile can accelerate rapport. The key is timing: smile as you greet, then calibrate to the buyer's style within seconds. The goal isn't cheeriness; it's creating a cooperative atmosphere where tough topics (risk, price, delivery dates) can be discussed without posturing. Mini-summary: Smile first, calibrate fast. Do now: Add “reset face → greet with smile” to your pre-meeting checklist. How can using names increase influence without sounding fake? Use names sparingly at moments of emphasis. Offer your own name first, confirm pronunciation, then use theirs to mark alignment and commitment—never as filler. In group settings with multiple stakeholders, sketch a quick seating map to avoid missteps later. This habit personalises without pandering and helps you track the real decision network behind procurement. Close clearly: “Aiko-san, we'll send the red-lined MSA by Friday.” Mini-summary: Names for signal, not filler. Do now: Practise name recall and pronunciation before the meeting. What's the cross-market playbook (Japan vs US vs Europe) for relationship momentum? Universal habits, local nuance. The same three behaviours—interest, smile, names—work everywhere, but settings differ. In Japan, invest more time upfront on context and internal harmony; be precise with honorifics and follow through meticulously. In the US, move faster to value articulation and next steps, keeping warmth high. In Europe, expect variance (Nordics vs DACH vs Southern Europe) in decision cadence and consensus. Align to company type: startups reward speed and flexibility; multinationals reward consistency and risk management. Hybrid selling post-2020 demands tighter summaries and clearer asynchronous follow-ups. Mini-summary: Universal habits, local settings. Do now: Add a “market nuance” line to every call plan. How do I turn these habits into a repeatable system my team can use? System beats intention. Bake the habits into templates, rituals, and measurable checkpoints. Create a pre-call sheet with (1) three curiosity questions, (2) a reminder to smile on entry, (3) stakeholder names and pronunciations, (4) a 90-second recap script for follow-ups. In your CRM, add fields for “buyer language used,” “stakeholder map,” and “adoption risk notes.” In weekly pipeline reviews, inspect not just stages but relationship signals: trust markers logged, name usage at key moments, and recap emails sent within 24 hours. Train using short, scenario-based drills (enterprise renewal, startup pilot, public-sector RFP). Mini-summary: Process it so it happens. Do now: Standardise a one-page “relationship checklist.” Final wrap Make the buyer—the human—the centre of the conversation. Start with interest, open with a smile, and use names with intent. Then systemise the behaviours so they happen every time. When products look similar, these micro-habits become the differentiator. About the author Dr. Greg Story, Ph.D. in Japanese Decision-Making, is President of Dale Carnegie Tokyo Training and Adjunct Professor at Griffith University. He is a two-time winner of the Dale Carnegie “One Carnegie Award” (2018, 2021) and recipient of the Griffith University Business School Outstanding Alumnus Award (2012). As a Dale Carnegie Master Trainer, Greg is certified to deliver globally across all leadership, communication, sales, and presentation programs, including Leadership Training for Results. He has written several books, including three best-sellers — Japan Business Mastery, Japan Sales Mastery, and Japan Presentations Mastery — along with Japan Leadership Mastery and How to Stop Wasting Money on Training. His works have been translated into Japanese, including ザ営業, プレゼンの達人, トレーニングでお金を無駄にするのはやめましょう, and 現代版「人を動かす」リーダー. Greg also publishes daily business insights on LinkedIn, Facebook, and Twitter, and hosts six weekly podcasts. On YouTube, he produces The Cutting Edge Japan Business Show, Japan Business Mastery, and Japan's Top Business Interviews.

NFPA standards can be lengthy and hard to follow; fortunately, we've got Jeff Stull here to break down what you need to know, particularly as it relates to the newest big development — the consolidation of key PPE and SCBA standards into NFPA 1850. Stull shares insights into the standards-development process and why it's always a “game of trade-offs” — gear that provides the best protection while still allowing you to get the job done. Check out these additional resources: The Standards Series Stull's FireRescue1 column: PPE update Webinar: Navigating the NFPA 1851 and 1852 merger into NFPA 1850 This episode of the Better Every Shift podcast is sponsored by MSA, the world's leading manufacturer of high quality, fire-rescue and safety solutions, protecting first responders around the world since 1914. For more information, visit MSAfire.com. Enjoying the show? Please take a moment to rate and review us on Apple Podcasts. You can also follow the show on Apple Podcasts, Spotify or wherever you listen to your podcasts. And email bettereveryshift@firerescue1.com to share your feedback.

The Windows 25H2 update is shrouded in mystery, but does it actually bring anything new to the table... or just more headaches for upgraders? Paul has been updating the Field Guide for 25H2, which will be an all-new addition. This is a chance to re-evaluate workarounds on unsupported hardware. This one still works: You can easily upgrade any Windows 10 or 11 PC, supported or not, using the 25H2 ISO and the D:setup.exe /product server command line. Windows 11 25H2 is out. Or is it? (New segment: This week in no one has 25H2 yet) New Dev and Beta builds enforce MSA at first sign-in This is the right choice for everybody, and enthusiasts can still use a local account sign-in After a leak, Microsoft announces new OneDrive client with Copilot integration and agents are on the way (of course they are), with new mobile clients etc. Mozilla Firefox finally supports profiles, PWAs Also, Brave has over 100 million users now AI OpenAI inks a major deal with AMD too ChatGPT is now a platform with support for third-party apps Perplexity Comet now free to all with usage limits Xbox and gaming Hand-wringing over Xbox reaches all-time high with Game Pass Ultimate price hike How bad is it and what can Xbox do to reassure fans? Microsoft: Just kidding on Game Pass Ultimate price hike, but only in certain countries Microsoft: No, we have not cancelled the next-gen Xbox console Hands-on with the Legion Go 2! Windows can work as a mobile gaming platform. Just not right now New Game Pass titles across PC, console, and cloud for early October a bit later than usual Free, ad-supported Xbox Cloud Gaming tier is on the way Total victory for Epic Games in Epic v. Google, Google must open up Play Store this month Tips & picks Tip of the week: Upgrade to Windows 11 on unsupported hardware App pick of the week: Opera Neon RunAs Radio this week: Managing for Failure with Amy Norris Brown liquor pick of the week: Weller 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: helixsleep.com/windows 1password.com/windowsweekly zapier.com/windows

The Windows 25H2 update is shrouded in mystery, but does it actually bring anything new to the table... or just more headaches for upgraders? Paul has been updating the Field Guide for 25H2, which will be an all-new addition. This is a chance to re-evaluate workarounds on unsupported hardware. This one still works: You can easily upgrade any Windows 10 or 11 PC, supported or not, using the 25H2 ISO and the D:setup.exe /product server command line. Windows 11 25H2 is out. Or is it? (New segment: This week in no one has 25H2 yet) New Dev and Beta builds enforce MSA at first sign-in This is the right choice for everybody, and enthusiasts can still use a local account sign-in After a leak, Microsoft announces new OneDrive client with Copilot integration and agents are on the way (of course they are), with new mobile clients etc. Mozilla Firefox finally supports profiles, PWAs Also, Brave has over 100 million users now AI OpenAI inks a major deal with AMD too ChatGPT is now a platform with support for third-party apps Perplexity Comet now free to all with usage limits Xbox and gaming Hand-wringing over Xbox reaches all-time high with Game Pass Ultimate price hike How bad is it and what can Xbox do to reassure fans? Microsoft: Just kidding on Game Pass Ultimate price hike, but only in certain countries Microsoft: No, we have not cancelled the next-gen Xbox console Hands-on with the Legion Go 2! Windows can work as a mobile gaming platform. Just not right now New Game Pass titles across PC, console, and cloud for early October a bit later than usual Free, ad-supported Xbox Cloud Gaming tier is on the way Total victory for Epic Games in Epic v. Google, Google must open up Play Store this month Tips & picks Tip of the week: Upgrade to Windows 11 on unsupported hardware App pick of the week: Opera Neon RunAs Radio this week: Managing for Failure with Amy Norris Brown liquor pick of the week: Weller 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: helixsleep.com/windows 1password.com/windowsweekly zapier.com/windows

The Windows 25H2 update is shrouded in mystery, but does it actually bring anything new to the table... or just more headaches for upgraders? Paul has been updating the Field Guide for 25H2, which will be an all-new addition. This is a chance to re-evaluate workarounds on unsupported hardware. This one still works: You can easily upgrade any Windows 10 or 11 PC, supported or not, using the 25H2 ISO and the D:setup.exe /product server command line. Windows 11 25H2 is out. Or is it? (New segment: This week in no one has 25H2 yet) New Dev and Beta builds enforce MSA at first sign-in This is the right choice for everybody, and enthusiasts can still use a local account sign-in After a leak, Microsoft announces new OneDrive client with Copilot integration and agents are on the way (of course they are), with new mobile clients etc. Mozilla Firefox finally supports profiles, PWAs Also, Brave has over 100 million users now AI OpenAI inks a major deal with AMD too ChatGPT is now a platform with support for third-party apps Perplexity Comet now free to all with usage limits Xbox and gaming Hand-wringing over Xbox reaches all-time high with Game Pass Ultimate price hike How bad is it and what can Xbox do to reassure fans? Microsoft: Just kidding on Game Pass Ultimate price hike, but only in certain countries Microsoft: No, we have not cancelled the next-gen Xbox console Hands-on with the Legion Go 2! Windows can work as a mobile gaming platform. Just not right now New Game Pass titles across PC, console, and cloud for early October a bit later than usual Free, ad-supported Xbox Cloud Gaming tier is on the way Total victory for Epic Games in Epic v. Google, Google must open up Play Store this month Tips & picks Tip of the week: Upgrade to Windows 11 on unsupported hardware App pick of the week: Opera Neon RunAs Radio this week: Managing for Failure with Amy Norris Brown liquor pick of the week: Weller 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: helixsleep.com/windows 1password.com/windowsweekly zapier.com/windows

The Windows 25H2 update is shrouded in mystery, but does it actually bring anything new to the table... or just more headaches for upgraders? Paul has been updating the Field Guide for 25H2, which will be an all-new addition. This is a chance to re-evaluate workarounds on unsupported hardware. This one still works: You can easily upgrade any Windows 10 or 11 PC, supported or not, using the 25H2 ISO and the D:setup.exe /product server command line. Windows 11 25H2 is out. Or is it? (New segment: This week in no one has 25H2 yet) New Dev and Beta builds enforce MSA at first sign-in This is the right choice for everybody, and enthusiasts can still use a local account sign-in After a leak, Microsoft announces new OneDrive client with Copilot integration and agents are on the way (of course they are), with new mobile clients etc. Mozilla Firefox finally supports profiles, PWAs Also, Brave has over 100 million users now AI OpenAI inks a major deal with AMD too ChatGPT is now a platform with support for third-party apps Perplexity Comet now free to all with usage limits Xbox and gaming Hand-wringing over Xbox reaches all-time high with Game Pass Ultimate price hike How bad is it and what can Xbox do to reassure fans? Microsoft: Just kidding on Game Pass Ultimate price hike, but only in certain countries Microsoft: No, we have not cancelled the next-gen Xbox console Hands-on with the Legion Go 2! Windows can work as a mobile gaming platform. Just not right now New Game Pass titles across PC, console, and cloud for early October a bit later than usual Free, ad-supported Xbox Cloud Gaming tier is on the way Total victory for Epic Games in Epic v. Google, Google must open up Play Store this month Tips & picks Tip of the week: Upgrade to Windows 11 on unsupported hardware App pick of the week: Opera Neon RunAs Radio this week: Managing for Failure with Amy Norris Brown liquor pick of the week: Weller 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: helixsleep.com/windows 1password.com/windowsweekly zapier.com/windows

The Windows 25H2 update is shrouded in mystery, but does it actually bring anything new to the table... or just more headaches for upgraders? Paul has been updating the Field Guide for 25H2, which will be an all-new addition. This is a chance to re-evaluate workarounds on unsupported hardware. This one still works: You can easily upgrade any Windows 10 or 11 PC, supported or not, using the 25H2 ISO and the D:setup.exe /product server command line. Windows 11 25H2 is out. Or is it? (New segment: This week in no one has 25H2 yet) New Dev and Beta builds enforce MSA at first sign-in This is the right choice for everybody, and enthusiasts can still use a local account sign-in After a leak, Microsoft announces new OneDrive client with Copilot integration and agents are on the way (of course they are), with new mobile clients etc. Mozilla Firefox finally supports profiles, PWAs Also, Brave has over 100 million users now AI OpenAI inks a major deal with AMD too ChatGPT is now a platform with support for third-party apps Perplexity Comet now free to all with usage limits Xbox and gaming Hand-wringing over Xbox reaches all-time high with Game Pass Ultimate price hike How bad is it and what can Xbox do to reassure fans? Microsoft: Just kidding on Game Pass Ultimate price hike, but only in certain countries Microsoft: No, we have not cancelled the next-gen Xbox console Hands-on with the Legion Go 2! Windows can work as a mobile gaming platform. Just not right now New Game Pass titles across PC, console, and cloud for early October a bit later than usual Free, ad-supported Xbox Cloud Gaming tier is on the way Total victory for Epic Games in Epic v. Google, Google must open up Play Store this month Tips & picks Tip of the week: Upgrade to Windows 11 on unsupported hardware App pick of the week: Opera Neon RunAs Radio this week: Managing for Failure with Amy Norris Brown liquor pick of the week: Weller 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: helixsleep.com/windows 1password.com/windowsweekly zapier.com/windows

The Windows 25H2 update is shrouded in mystery, but does it actually bring anything new to the table... or just more headaches for upgraders? Paul has been updating the Field Guide for 25H2, which will be an all-new addition. This is a chance to re-evaluate workarounds on unsupported hardware. This one still works: You can easily upgrade any Windows 10 or 11 PC, supported or not, using the 25H2 ISO and the D:setup.exe /product server command line. Windows 11 25H2 is out. Or is it? (New segment: This week in no one has 25H2 yet) New Dev and Beta builds enforce MSA at first sign-in This is the right choice for everybody, and enthusiasts can still use a local account sign-in After a leak, Microsoft announces new OneDrive client with Copilot integration and agents are on the way (of course they are), with new mobile clients etc. Mozilla Firefox finally supports profiles, PWAs Also, Brave has over 100 million users now AI OpenAI inks a major deal with AMD too ChatGPT is now a platform with support for third-party apps Perplexity Comet now free to all with usage limits Xbox and gaming Hand-wringing over Xbox reaches all-time high with Game Pass Ultimate price hike How bad is it and what can Xbox do to reassure fans? Microsoft: Just kidding on Game Pass Ultimate price hike, but only in certain countries Microsoft: No, we have not cancelled the next-gen Xbox console Hands-on with the Legion Go 2! Windows can work as a mobile gaming platform. Just not right now New Game Pass titles across PC, console, and cloud for early October a bit later than usual Free, ad-supported Xbox Cloud Gaming tier is on the way Total victory for Epic Games in Epic v. Google, Google must open up Play Store this month Tips & picks Tip of the week: Upgrade to Windows 11 on unsupported hardware App pick of the week: Opera Neon RunAs Radio this week: Managing for Failure with Amy Norris Brown liquor pick of the week: Weller 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: helixsleep.com/windows 1password.com/windowsweekly zapier.com/windows

Join host Rahul K. Shah, MD, MBA, AAO-HNS EVP and CEO, for a historic conversation with two pioneers of surgical sleep medicine, Kathleen Yaremchuk, MD, MSA and B. Tucker Woodson, MD. Both were at Henry Ford Health in the early 1980s—the epicenter of American surgical sleep medicine—where they witnessed the birth of modern sleep apnea treatment. In this episode, discover how sleep apnea went from an unrecognized condition treated only with tracheotomy to a field with multiple treatment modalities. Dr. Yaremchuk and Dr. Woodson share firsthand accounts of working with Dr. Shiro Fujita as he adapted a Japanese snoring procedure into the groundbreaking UPPP surgery, trace the evolution from skeletal and soft tissue surgeries to neuromodulation with Inspire therapy, and discuss the newest frontier: pharmaceutical treatments including GLP-1 medications. This conversation spans four decades of innovation and offers a rare glimpse into the future of otolaryngology's continued role in sleep medicine.

Cette semaine, je reçois mon bon ami Jay pour qu'il nous parle du tournant dans sa carrière, alors qu'il se lance à fond dans le sport d'endurance avec humilité et plaisir. Il nous raconte sa préparation pour le 125kms de l'UTHC et nous fait également le récit de sa course. On lance également la saveur Upika Endurance X Jay Du Temple à la pêche.

Parkinsonism is the term used to refer to a group of conditions – like multiple system atrophy (MSA), progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and Lewy Body Dementia – which resemble Parkinson's in some of their symptoms. To discuss these sibling conditions, the Movers & Shakers are joined at the pub by guests from across the spectrum who share their stories – often very uplifting – about learning to live with the new realities brought on by their illnesses.Sponsored by Albion Chambers.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Brethren, this Short Talk Bulletin Podcast episode was written by RW Bro Stewart M. L. Pollard, Past Executive Secretary of the MSA, and is brought to us by WBro David Koncz, PM – United #8 ME. A recent survey asked the question: What is the most pressing problem facing the Craft today? Here we find […]

In episode 217, host Galit Friedlander and guest Ana Rokafella Garcia (legendary b-girl, co-founder of Full Circle Productions, choreographer, filmmaker, and adjunct professor at The New School), dive into the history, evolution, and impact of hip-hop. From growing up in New York City during the fires, crack epidemic, and AIDS crisis to discovering her voice in cyphers and clubs, Rokafella shares how dance carved out a future for her. She reflects on commercialization, gender dynamics, and visibility in the scene, while urging today's dancers to stay grounded in the culture's foundations. The conversation also touches on breaking at the Olympics, the tension between competition and community, and why hip-hop's resilience continues to guide her work. Follow Galit: Instagram - https://www.instagram.com/gogalit Website - https://www.gogalit.com/ On-Demand Fitness Courses - https://galit-s-school-0397.thinkific.com/collections Follow Rokafella: Instagram - https://www.instagram.com/larokafella Website - https://larokasoul.com/ Full Circle: https://www.instagram.com/fullcirclesouljahs Behind the Groove: https://www.instagram.com/behindthegroovenyc/ All the Ladies Say: https://www.instagram.com/alltheladiessay Listen to DanceSpeak on Apple Podcasts and Spotify.

Behind every thriving Med Spa is a team that believes in the mission. In this episode, I sit down with the powerhouse team from Radiance Beautiful Skin, CEO Tara VanderValk, Kristin Whittington, Ana Broadwater, and Sarah Griffin, to talk about how implementing a signature menu and annual consultation process transformed their retention, confidence, and alignment. We dive into what it's like to be coached together inside Med Spa Advantage, how they shifted from on-the-fly treatment plans to confidently presenting signature packages, and how the CARES consult process has strengthened their client relationships. We also break down the mindset shifts around selling with integrity, growing leadership, and building a team culture that lasts. Tune in to hear how this team moved from sales resistance to service-aligned confidence.   HIGHLIGHTS Why clients expect expert recommendations. What made them join Med Spa Advantage (MSA) despite already being successful. How having a signature menu gives providers clarity and confidence. Using the signature consult with returning clients to increase retention. Mindset shifts from the MSA team coaching calls. How to shift from selling to prescribing outcomes. Advice for hiring high-integrity team members.   RESOURCES + LINKS Learn more about Radiance Beautiful Skin HERE Try Ask Heather AI for 30 Days HERE  Apply for The Med Spa Advantage HERE    FOLLOW Heather: @heatherterveen Website: heatherterveen.com Radiance Beautiful Skin: @radiance_beautifulskin

MSA in 5 from Man Seeks Adventure Brad Fanshaw and Dave Marek have some great tips. EPISODE 117 Hear About: • Everything About Your Balls. • TV History • Micro Trips VISIT US: www.ManSeeksAdventure.com FOLLOW US ON INSTAGRAM @manseeksadventure @Bradley_Fanshaw @davidwmarek

MSA in 5 from Man Seeks Adventure Brad Fanshaw and Dave Marek have some great tips. EPISODE 116 Hear About: • Great Diners Along California's Hwy 1. • BALLARD TV Show with Maggie Q. VISIT US: www.ManSeeksAdventure.com FOLLOW US ON INSTAGRAM @manseeksadventure @Bradley_Fanshaw @davidwmarek

Progressive supranuclear palsy and corticobasal syndrome are closely related neurodegenerative disorders that present with progressive parkinsonism and multiple other features that overlap clinically and neuropathologically. Early recognition is critical to provide appropriate treatment and supportive care. In this episode, Teshamae Monteith, MD, FAAN speaks with Nikolaus R. McFarland, MD, PhD, FAAN, author of the article “Progressive Supranuclear Palsy and Corticobasal Syndrome” in the Continuum® August 2025 Movement Disorders issue. Dr. Monteith is the associate editor of Continuum® Audio and an associate professor of clinical neurology at the University of Miami Miller School of Medicine in Miami, Florida. Dr. McFarland is an associate professor of neurology at the University of Florida College of Medicine at the Norman Fixel Institute for Neurological Diseases in Gainesville, Florida. Additional Resources  Read the article: Progressive Supranuclear Palsy and Corticobasal Syndrome Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @headacheMD Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Monteith: Hi, this is Dr Teshamae Monteith. Today I'm interviewing Dr Nikolaus McFarland about his article on progressive supranuclear palsy and cortical basilar syndrome, which appears in the August 2025 Continuum issue on movement disorders. Welcome, how are you? Dr Farland: I'm great. Thank you for inviting me to do this. This is a great opportunity. I had fun putting this article together, and it's part of my passion. Dr Monteith: Yes, I know that. You sit on the board with me in the Florida Society of Neurology and I've seen your lectures. You're very passionate about this. And so why don't you first start off with introducing yourself, and then tell us just a little bit about what got you interested in this field. Dr Farland: I'm Dr Nicholas McFarlane. I'm an associate professor at the University of Florida, and I work at the Norman Fixel Institute for Neurological Diseases. I am a director of a number of different centers. So, I actually direct the cure PSP Center of Care and the MSA Center of Excellence at the University of Florida; I also direct the Huntington's clinic there as well. But for many years my focus has been on atypical parkinsonisms. And, you know, I've treated these patients for years, and one of my focuses is actually these patients who suffer from progressive supranuclear palsy and corticobasal syndrome. So that's kind of what this review is all about. Dr Monteith: You probably were born excited, but I want to know what got you interested in this in particular? Dr Farland: So, what got me interested in this in particular was really the disease and the challenges that's involved in it. So, Parkinson's disease is pretty common, and we see a lot of that in our clinic. Yet many times, roughly about 10 to 15% of my patients present with these atypical disorders. And they're quite fascinating. They present in different ways. They're fairly uncommon. They're complex disorders that progress fairly rapidly, and they have multiple different features. They're sort of exciting to see clinically as a neurologist. I think they're really interesting from an academic standpoint, but also in the standpoint of really trying to bring together sort of a team. We have built a multidisciplinary team here at the University of Florida to take care of these patients. They require a number of folks on that team to take care of them. And so, what's exciting, really, is the challenge of treating these patients. There are very limited numbers of therapies that are available, and the current therapies that we have often really aren't great and over time they fail. And so, part of the challenge is actually doing research. And so, there's actually a lot of new research that's been going on in this field. Recently, there's been some revisions to the clinical criteria to help diagnose these disorders. So, that's really what's exciting. The field is really moving forward fairly rapidly with a number of new diagnostics, therapeutics coming out. And hopefully we can make a real difference for these patients. And so that's what really got me into this field, the challenge of trying to treat these patients, help them, advocate for them and make them better. Dr Monteith: And so, tell me what the essential points of this article. Dr Farland: So, the essential points, really, of this article is: number one, you know, just to recognize the new clinical criteria for both PSP and corticobasal syndrome, the diagnosis for these disorders or the phenotypic spectrum has really expanded over the years. So, we now recognize many different phenotypes of these disorders, and the diagnosis has gotten fairly complicated. And so, one of the goals of this article was to review those new diagnostic criteria and the different phenotypic ways these diseases present. I wanted to discuss, also, some of the neuropathology and clinicopathological overlap that's occurred in these diseases as well as some of the new diagnostic tests that are available. That's definitely growing. Some of the new studies that are out, in terms of research and clinical trials. And then wanted to review some of the approaches for treatment for neurologists. Particularly, we're hoping that, you know, this article educates folks. If you're a general neurologist, we're hoping that recognizing these diseases early on will prompt you to refer these patients to specialty clinics or movement disorder specialists early on so they can get appropriate care, confirm your diagnosis, as well as get them involved in trials if they are available. Dr Monteith: And how has the clinical criteria for PSP and cortical basilar syndrome changed? Dr Farland: I think I already mentioned there's been an evolution of the clinical criteria for PSP. There's new diagnostic criteria that were recently published, and it recognizes the multiple clinical phenotypes and the spectrum of the disease that's out there, which is much broader than we thought about. Corticobasal clinical criteria are the Dr Armstrong criteria from 2013. They have not been updated, but they are in the works of being updated. But it does recognize the classic presentation of corticobasal syndrome, plus a frontal executive predominant and then a variant that actually overlaps with PSP. So, there's a lot more overlap in these two diseases than we originally recognized. Dr Monteith: And so, you spoke a bit about FTD spectrum. So why don't you tell us a little bit about what that is? I know you mentioned multiple phenotypes. Dr Farland: What I really want to say is that both PSP and corticobasal syndrome, they're relatively rare, and what- sort of as to common features, they both are progressive Parkinson disorders, but they have variable features. While they're commonly associated with Parkinson's, they also fit within this frontotemporal lobar spectrum, having features that overlap both clinically and neuropathologically. I just want folks to understand that overlap. One of this pathological overlap here is the predominant Tau pathology in the brain, an increasing recognology- recognition of sort of the pathological heterogeneity within these disorders. So, there's an initial description, a classic of PSP, as Richardson syndrome. But now we recognize there are lots of different features to it and there are different ways it presents, and there's definitely a lot of clinical pathological overlap. Dr Monteith: Why don't we just talk about some red flags for PSP? Dr Farland: Yeah, sure. So, some of the red flags for PSP and even corticobasal syndrome are: number one is rapid progression with early onset of falls, gait difficulty, falling typically backwards, early speech and swallow problems that are more prominent than you see in Parkinson's disease, as well as eye gaze issues. So, ocular motor features, particularly vertical gaze palsy. In particular what we talk about is the supranuclear gaze palsy, and one of the most sensitive features that we've seen with these is downgaze limitation or slowed downgaze, and eventually a full vertical gaze palsy and followed supranuclear gaze palsy. So, there's some of the red flags that we see. So, while we think about the lack of response to levodopa frequently as something that's a red flag for Parkinson's, there are many times that we see Parkinson's patients, and about a quarter of them don't really respond. There's some features that don't respond to levodopa that may not be so specific, but also can be helpful in this disease. Dr Monteith: And what about the red flags for cortical basilar syndrome? Dr Farland: So, for cortical basilar syndrome, some of the red flags again are this rapidly depressive syndrome tends to be, at least in its classical present presentation, more asymmetric in its presentation of parkinsonism, with features including things like dystonic features, okay? For limb dystonia and apraxias---so, inability to do a learned behavior. One of those red flags is a patient who comes in and says, my hand doesn't work anymore, which is something extremely uncommon that you hear in Parkinson's disease. Most of those patients will present, say, I might have a tremor, but they very rarely will tell you that I can't use my hand. So look out for that sign. Dr Monteith: And let's talk a little bit about some of the advances in the fields you mentioned, evolving biomarker and imaging capacities. So, how are these advances useful in helping us understand these conditions, especially when there's so much heterogeneity? Dr Farland: I might start by talking a little bit about some of the clinical criteria that have advanced. Why don't we start there and just discuss some of the advances? I think in PSP, I think, originally we had both probable and possible diagnoses of PSP, and the diagnostic criteria were basically focused on what was what's called “classical PSP” or “Richardson syndrome”. But now we recognize that there are multiple phenotypes. There's an overlap with Parkinsonism that's slower in progression and morphs into PSP, the classical form. There's a frontal behavioral variant where patients present with that frontal behavioral kind of thing. There's a speech-language variant that can overlap with PSP. So they have prominent speech language, potentially even apraxia speech. So, recognition of these different phenotypes is sort of a new thing in this field. There's even overlap with cortical basal syndrome and PSP, and we note that the pathology can overlap as well. So, I think that's one of the things that have changed over time. And these were- recently came out in 2017 in a new publication in the Movement Disorders Society. So, in terms of diagnostic tests as well---and there's been quite a bit of evolution---really still to date, our best diagnostic test is imaging. MRI is really one of our best tests currently. Currently blood tests, spinal fluid, there's new biomarkers in terms of skin… they're still in the research phase and not necessarily very specific yet. So, we rely heavily on imaging still; and for PSP, what we're looking for largely are changes in the brain stem, and particularly focused on the midbrain. So disproportionate midbrain atrophy compared to the pons and the rest of the midbrain is a fairly specific intensive sign for PSP. Whereas in MSA we see more of a pontine atrophy compared to the midbrain. So that can be really helpful, and there are lots of different new measurements that can be done. PET scans are also being used as well. And there are new PET markers, but they still remain kind of research-based, but are becoming more and more prevalent and may be available soon for potential use. Although there's some overlap with PET tracers with Alzheimer's disease and different Tau isoforms. So, something to be wary about, but we will be seeing some of these soon coming out as well. More kind of up-to-date things include things like the spinal fluid as well as even some of the skin biopsies. And I think we've heard some word of recent studies that have come out that potentially in the very near future we might actually have some Tau protein tests that we can look at Tau either in spinal fluid or even in a skin biopsy. But again, still remains research-based and, we still need more information as to whether these tests can be reproducible and how sensitive or specific they are. Dr Monteith: It sounds like, when really approaching these patients, still, it's a lot of back to the history, back to the clinical and some basic imaging that we should be able to identify to distinguish these types of patients, and we're not quite where we need to be yet for biomarker. Dr Farland: I totally agree with you. I think it starts, really, with the clinical exam and that's our main focus here; and understanding some of the new clinical criteria which are more sensitive, but also specific, too. And they're really useful to look at. So, I think reviewing those; patients do progress, following them over time can be really useful. And then for diagnosis, getting imaging if you suspect a patient has an atypical presentation of parkinsonism, to look for signs or features that might be specific for these different disorders. Dr Monteith: Why don't we take a typical case, a typical patient that you would see in clinic, and walk us through the thought process---especially, maybe they presented somewhat early---and the different treatment approaches to helping the patient, and of course their family. Dr Farland: Yeah, sure. So, a typical patient might be someone who comes in with, like, a three year history of progressive gait problems and falling. And let's say the patient says, I'm falling backwards frequently. They may have had, like, a rib fracture, or they hit their head once, and they're describing some speech issues as well. Now they're relying on a walker and family members saying they rarely let them be by themselves. And there may be some slowing of their cognitive function and maybe a bit of withdrawal. So that's a typical patient. So, the approach here is really, what are some of the red flags? I think already you hear a red flag of a rapidly progressive disease. So, Parkinson's disease patients rarely have frequent falls within the first five years. So, this is within three years or less. You're already hearing early onset of gait problems and falling, and particularly falling backwards rather than forwards as often Parkinson's disease patients do. You're hearing early speech problems and maybe a subtle hint of cognitive slowing and some withdrawal. So, a lot of things that sort of are red flags. So, our approach really would be examining this patient really closely. Okay? We'd be listening to the history, looking at the patient. One thing is that some of these patients come in, they may be in a wheelchair already. That's a red flag for us. If they're wearing sunglasses---sometimes we see that patients, they have photosensitivity and they're in a chair and they're wearing sunglasses---you take the glasses off and you look at their face and they have that sort of a facial stare to them---not just the masked face, but the stare---and their eyes really aren't moving. So, another kind of clue, maybe this is probably something atypical, particularly PSP is what I'm thinking about. So, the approach is really, do a thorough exam. I always recommend looking at eye movements and starting with volitional saccades, not giving them a target necessarily, but asking them to look up and then look down. And then particularly look at the speed of downgaze and whether they actually have full versions down, are able to do that. That's probably your most sensitive test for a patient who has PSP. Not the upgaze, which can be- upgaze impairment in older patients can be nonspecific. So, look for that down gaze. So, if I can get out one message, that's one thing that can be easily done and examined fairly quickly for diagnosis of these patients. And then just look for signs of rigidity, bradykinesia, maybe even some myelopraxia, and then look at their gait carefully so that there's a high suspicion. Again, if there's some atypical features, imaging is really important. So, my next step would be probably getting an MRI to evaluate whether- do they have brain somatrophy or other widespread atrophy or other signs? You need to think about your differential diagnosis for some of these patients as well. So, common things are common; vascular disease, you can't have vascular parkinsonism or even signs of NPH. Both of those can present with progressive gait difficulty and falls. So, the gait may look more like Parkinson's rather than ataxic gait that we see in classic PSP, but still they have early gait issues, and that can be a mimicker of PSP, So looking for both of those things in your imaging. Think about sort of autoimmune potentially causes. So, if they have a really rapid progressive cause, there are some rare autoimmune things. There have been recent reports of things like IgLON5, although there's limited cases, but we're doing more screening for some of those autoimmune causes. And then even some infectious causes like Whipples, that are rarely present like this. Okay? And have other signs and features. Dr Monteith: So, let's say you diagnose this patient with PSP and you're assessing the patients to see how you can improve their quality of life. So, what are some potential symptomatic managements that will help our patient? Dr Farland: I recommend for most all of these patients… while the literature indicates that many patients with PSP, and especially corticobasal syndrome, don't respond well to levodopa. So, the classic treatment for parkinsonism. However, we all recommend a trial of levodopa. These patients may respond partially to doses of levodopa, and we try to push the doses a bit higher. So, the recommended trial is usually a dose up to roughly 1000 milligrams of levodopa per day. And give it some time, at least two, if not actually three months of a trial. If not well-tolerated, you can back off. If there's no response at all or no improvement, then slowly back off and taper patients off and ask them to tell you whether they feel like they're actually worsening. So, many patients, sometimes, don't recognize the improvements, or family members don't recognize it until we actually taper them back off. And they may end up saying there are some other things that even recognize. Even some nonmotor benefits can be seen with levodopa. In some cases, we do keep them on levodopa, but levodopa's our best therapy for this. Dopamine agonists, MAO inhibitors, have all been sort of tried and they've been studied, but often don't really help or fail to help benefit these patients and could be fraught with some other side effects. I think many people do also turn to Amantadine as a treatment for Parkinson's, gait problems, freezing, if you see it in these disorders. Yet Amantadine is fraught with issues of side effects, including cognitive issues, and I think is not well-tolerated. But there are the rare patient who actually does respond to this or claims they respond to this. By and large, these patients relentlessly progress, unfortunately. So, beside treatment of other symptoms, I think it's really important to recognize that they require supportive cares and therapy. So, starting those early on and getting your allied healthcares kind of involved. So that includes people like physical, occupational therapy for the gait issues, the falls, occupational therapy for doing daily activities. Speech language pathology can be really a critical player for these because of the early speech and language issues, as well as swallow difficulties. Swallow is compared quickly in these patients. And so, we do recommend the screening evaluation, then often following patients either every six- or even annually, at least, with a swallow evaluation. And we recommend the fluoroscopic-guided kind of modified barium swallow for these patients.  Dr Monteith: And how does that differ if, let's say, the patient had cortical basilar syndrome? What are some of the symptomatic treatments that would be high on your consideration? Dr Farland: So actually, these patients also have a very similar approach, and they often have some overlapping features. Maybe a little bit of difference in terms of the level of apraxia and some dystonic features that you see in corticobasal syndrome. So, as I mentioned earlier that these patients have a more typ- when they present, typically have a more asymmetric presentation. And one of the biggest issues is this limb apraxia. They may have abnormal movements as well as, like, the alien limb-type phenomena as well. So, the focus of therapy, while similar in the sense we focus on the parkinsonism, I do always try levodopa and try to ramp up the doses to see if it benefits. It does often fail, but it's definitely worth trying. The other focus of these patients is trying to treat symptoms. Dystonia, those features… in some cases, we can help; if it's painful or uncomfortable, muscle relaxants can be used. If it's vocal, things like Botox can be really helpful. Often times it is more palliative than actually restorative in terms of function, but still can be really helpful for patients who ask about pain and discomfort and trying to treat. And then of course, again, the focus on our supportive care. We need to build that network and build that team of folks, the therapists, the physical, occupational, and the speech therapist to help them. If they have language problems---like either in PSP or corticobasal---I'll also include my request to a speech language pathologist to work on cognitive function. That's a special, additional thing you have to ask for and then specifically request when you make a referral to a speech language pathologist. Dr Monteith: That is so important. I think keeping the simulation, keeping the social support, and I would probably guess that you would also include screening for sleep and mood disorder. Dr Farland: Absolutely. Mood disorders are really big in these diseases. Patients are suffering terribly. You do hear about labile mood in both of these diseases, particularly PSP; and even what's called pseudobulbar palsy, where the mood is not always congruent with the affect. So they may laugh or cry inappropriately, and particularly the crying can be very disturbing to family and caregivers to see that. And so, treating those things can be really important. So always asking about the mood issues. Depression in particular is something that we're very sensitive about, and there is a higher incidence of suicidal ideations. Asking about that and feeling and making sure that they are in a safe environment can be really important. Dr Monteith: Thank you so much. Dr Farland: Thank you. Dr Monteith: Today I've been interviewing Dr Nikolaus McFarland about his article on progressive supranuclear palsy and cortical basilar syndrome, which appears in the August 2025 Continuum issue on movement disorders. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

MSA in 5 from Man Seeks Adventure Brad Fanshaw and Dave Marek have some great tips. EPISODE 115 Hear About: • Monterey Car Week, the cars, the Fun, the Money! • A Hangover Burger in Anaheim. VISIT US: www.ManSeeksAdventure.com FOLLOW US ON INSTAGRAM @manseeksadventure @Bradley_Fanshaw @davidwmarek

MSA in 5 from Man Seeks Adventure Brad Fanshaw and Dave Marek have some great tips. EPISODE 114 Hear About: • The Days of the Long Three Martini Lunch May be Gone! • The Dark Web, What is it Really? VISIT US: www.ManSeeksAdventure.com FOLLOW US ON INSTAGRAM @manseeksadventure @Bradley_Fanshaw @davidwmarek

On Thursday's Mark Levin Show, Iran's nuclear ambitions and ballistic missile development pose an existential threat to Israel and American civilization, which cannot be ignored. Israel, possibly with U.S. assistance, will take military action to neutralize this threat, as Iran will not go away on its own. Iran's actions, including attacks via proxies and American casualties, demand a decisive military response, which is self-defense rather than nation-building. These radical Democrats, fifth-columnists, and isolationists lack any strategy and moral clarity. Also, the people of Israel are never discussed by the media. They face severe challenges every day, especially in Tel Aviv, where ballistic missiles from Iran target hospitals and public areas, forcing families into bomb shelters. They are in constant fear with a disrupted quality of life. Media outlets ignore these struggles and ignore the regime's history of killing and maiming American soldiers. Later, Zuhdi Jasser calls in and addresses the mindset of the isolationists and fifth columnists who deliberately ignore the existential threat posed by Iran's theocratic regime and its proxies like Hezbollah and the Houthis. He emphasizes that these groups are driven by a radical theology that glorifies suicide bombing, chaos, and the targeting of non-combatants, with the ultimate goal of triggering an apocalyptic scenario tied to the return of the 12th Imam. Jasser asserts that Iran's uranium enrichment is clearly aimed at developing nuclear weapons, not peaceful purposes, and warns that the regime would use such weapons, likening its leadership to a cult willing to commit national fratricide. Finally, Sayyid Qutb's book Milestones, promotes pure Islam and strict shariah, rejecting Western values and most modern Muslims as ignorant (jahiliyyah). Groups like CAIR, ISNA, ICNA, MSA, and MPAC dismiss devout Muslims who oppose their views. Qutb's ideas fuel sectarian violence and terrorism by groups like Hamas and al-Qaida, and states like Iran, which pursues nuclear weapons through deception (taqiyya). Western appeasement fails to counter this clash with democratic values. Learn more about your ad choices. Visit podcastchoices.com/adchoices