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About Tracy Gibbs:Tracy is a world-renowned formulator in the nutraceutical industry. He began his career while residing in Japan. Schooled in organic chemistry and botanical medicine (Kampo Igaku) receiving a Doctorate in Pharmacognosy. He is the formulator of over 1100 dietary supplements and skin care products and the developer of multiple patents in absorption enhancement technologies such as Liposomes, Nanoparticles, oral strip delivery, and enzyme-enhanced absorption. Tracy is also the author of four books and has taught and lectured at worldwide symposiums and conferences including the Malaysia Health Symposium, The Anti-Aging Association of Korea, The League of Cities and Towns USA, Biotech China, and the National Nutritional Foods Association. Tracy has worked in C-level positions for global nutritional companies for a majority of his career. In this episode, Jennie Bellinger and Tracy Gibbs discuss:Simple, dollar-based compensation planFounders as distributors, no salariesInnovative, natural product formulationsAdvanced delivery technologies (strips, liposomes)Addressing common needs (sleep, energy, immunity)Key Takeaways:Life Wise has designed a unique, simple compensation plan that pays distributors directly in dollars rather than complex point systems. Rather than drawing salaries, the founders of Life Wise have committed to being distributors themselves, and this aligns their interests with the field and allows them to quickly identify and address any issues with the compensation structure.Tracy Gibbs' extensive experience as a formulator has enabled Life Wise to develop high-quality, natural products that address common consumer needs like sleep, energy, and immunity. Life Wise offers a variety of delivery formats, including dissolvable oral strips that bypass the digestive system. By designing a simple system that even those new to network marketing can succeed in, Life Wise aims to provide opportunities for individuals who have historically struggled to find success in the industry."I have no problem saying I really think God is leading this company… Just when we're at the peak of having a huge IP problem, an old contact of ours, who is an IT professional, called us up and he said, “Hey, you guys have been on my heart. Do you need any help?” — Tracy GibbsConnect with Tracy Gibbs: LinkedIn URL: https://www.linkedin.com/in/tracygibbsformulator/Link to Gift from Tracy Gibbs:Tracy is giving away a five-day supply of their latest product called “Lift”! It is Energy, Hydration and Mood-enhancing all in one.To get it, simply send an email to vitamintracy@gmail.com with your:Namemailing addressmobile number Connect with Jennie:Website: https://badassdirectsalesmastery.com/Email: jennie@badassdirectsalesmastery.comFacebook personal page: https://facebook.com/jbellingerPLFacebook podcast page: http://facebook.com/BadassDirectSalesMasteryFacebook group for Badass Crew: https://facebook.com/groups/BadassDirectSalesMomsInstagram: https://instagram.com/BadassDirectSalesMasteryPersonal Instagram: https://instagram.com/jenniebellingerLinkedIn: https://linkedin.com/in/BadassDirectSalesMasteryThe Badass Direct Sales Mastery Podcast is currently sponsored by the following:Bella Grace Elixir: https://shopbellagrace.com/?ref=jenniebadassdirectsalesmasteryLeadBuddy Digital Marketing: Use code BDSM when checking out at https://leadbuddy.io/pro-monthly-9310?am_id=jennie582Show Notes by Podcastologist: Hanz Jimuel AlvarezAudio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it.
Autumn Greetings Glocal Citizens! It's a season of transformation from the vibrancy of summer sun to the rest, retreat and make ready energy of winter. Here on the podcast we're taking this time to explore new collaborations in conjunction with events happening in the coming months. First up is a collaboration with the Women of Africa Post-Pandemic Empowerment and Advocacy Programme which is an intitaitve of Glocal Citizen Adebisi Bright's (https://glocalcitizens.fireside.fm/guests/adebisi-bright) LiveWell Initiative based in Lagos Nigeria. This series of conversations with the practitioners partcipating in the progamme is a sneak preview of the upcoming dialogues. My guest this week, Egyptian pharmacist and entrpreneur, Dr. Wael Ali is a distinguished leader in pharmacy and public health with nearly 25 years of experience spanning clinical research, healthcare management, and international collaboration. As the President of the PharmaHelp Foundation Inc. and the Egyptian Organization of Pharmacy, he drives pharmacy practice transformation and workforce development. His roles as Vice President of FIP's EMROpharm Forum and Executive Committee Consultant at the University of Sharjah highlight his commitment to advancing pharmaceutical education and practice. He also has extensive pharmaceutical manufacturing experience as a CEO of American Pharmaceutical Industries based in Farifax, Virginia. His expertise spans community, hospital, military and emergency pharmacy practices as well as social and administrative pharmacy functions across Egypt, the Gulf Cooperation Council or GCC, and the USA. If you ever wondered about what does on behind the counter in your local pharmacy, this conversation will help shine a light on the many roles and responsibilities your neighborhood pharmacist often takes on. As an added bonus, Wael give us the crash course in on the ins and outs of manufacturing and exporting made in the USA products. Where to find Wael? On LinkedIn (https://www.linkedin.com/in/wael-ali-7944b01a7/) On Instagram (https://www.instagram.com/waelaliali1/) On Facebook (https://www.facebook.com/Dr.waelaliofficial/) On YouTube (https://www.youtube.com/@drwaelali6627) Other topics of interest: Historic Cairo, Egypt (https://whc.unesco.org/en/list/89/) Gulf Cooperation Council (https://en.wikipedia.org/wiki/Gulf_Cooperation_Council) On Liposome Manufacturing ([https://www.sciencedirect.com/science/article/pii/S0169409X20300788#:~:text=Liposomes are manufactured either by,manipulated for size (Section 2.1.](https://www.sciencedirect.com/science/article/pii/S0169409X20300788#:~:text=Liposomes are manufactured either by,manipulated for size (Section%202.1.)) About Medwatch (https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program) CIF vs FOP Shipping (https://www.investopedia.com/ask/answers/020215/what-difference-between-cif-and-fob.asp) International Pharmaceutical Federation (FIP) (https://www.fip.org) WHO facts on Hepatitis (https://www.who.int/health-topics/hepatitis#tab=tab_1) Special Guest: Adebisi Bright.
Dr. Chris Shade, an expert in detoxification and longevity medicine, joins Sinclair Kennally in this episode of "Your Health Reset." Driven by his passion for helping people recover from heavy metal, toxin, and mold exposures, Dr. Shade shares his journey from studying pollution as an organic farmer to addressing root causes. The conversation focuses on the importance of detoxification in longevity medicine and the role of up-regulating NRF2 and PK pathways for clearing toxins and promoting regenerative chemistry. Dr. Shade discusses the effectiveness of liposomal delivery, a natural method that utilizes liposomes to enhance the bioavailability of compounds like glutathione, lipoic acid, GABA, C, B, and D. Liposomes protect these compounds during digestion and facilitate absorption through the oral cavity and capillaries. Join Sinclair Kennally in the next episode for an engaging exploration of detoxification techniques and the potential impact of liposomal delivery on overall health and well-being. Highlights Some of our favorite highlights from this episode include: What do you mean murder? So Tim Gray calls up some of the Cutler groups and says, Hey, come to Health Optimization Summit, all of us biohackers in the world. All of the data on all of the things that down-regulate detoxification chronically? Do we ignore that? We know so much about endotoxemia and how it drives inflammation blocks, detoxification drives, neuroinflammation, drives the decay of the. You got myths on the natural medicine side and you got course tons of myths on the med, on the medical side. So on the medical side, Oh, detoxification is not real. That's natural health, functional medicine, or allopathic. So what are the myths that still persist in your eyes that we need to, you know? Well, you got myths on both sides. And it's blocking all of the inflammatory cascades of this advanced liver stagnation. And so, you know, doing that, bringing in bitters, you know, doing, you know, a formal detox with a lot of the push catch. Timestamps 00:03:00 Exploring Alternative Solutions to Amalgam Fillings: A Conversation with Dr. Christopher Shade 00:05:00 The Benefits of Liposomal Delivery for Detoxification and Regeneration 00:22:00 The Benefits of Detoxification for Stress and Health Conditions 00:36:00 Myth-Busting Chronic Illness: Exploring Natural and Allopathic Medicine 00:38:00 Discussion of the Cutler Protocol and its Impact on Health Optimization Subscribe to the Podcast here: Apple | Spotify | Stitcher Connect with Sinclair Kennally: Instagram: @detoxrejuvenation Website: https://detoxrejuvenation.com/
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.05.02.539100v1?rss=1 Authors: De La Torre, A., Huynh, T. N., Chang, C. C., Pooler, D. B., Ness, D., Lewis, L., Pannem, S., Feng, Y., Samkoe, K. S., Hickey, W. F., Chang, T. Y. Abstract: Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Joining us today is George Kokkinis, Technical Director of Pharmako Biotechnologies. And today, we are discussing advanced delivery systems for PEA. In this episode, George discusses:The difference between Liposomes, Nanoparticles, and other lipophilic delivery systemsThe common issues when it comes to the delivery of PEA Dosing issues, How high can you safely go, and how frequently do you have to take PEASafety concerns Research on PEA in health conditionsAbout GeorgeGeorge is Pharmako's Technical Director and Co-founder. He is the inventor of anumber of the technologies used in Pharmako's products and has 30 years ofexperience with the industry. George received his degree in chemistry from theAustralian National University and started his working career with the TherapeuticGoods Administration (TGA). The following nine years saw George into his last position within the TGA at an Executive Level 1, heading special projects in the Complementary Medicines Branch. He then switched to industry and went on to become the General Manager of a therapeutic goods regulatory consulting firm. He managed a portfolio of over 100 clients with over a thousand products. The next position was with a medicine manufacturing brand company as the GeneralManager, with the main tasks being to modernise the manufacturing arm, introduce new product development, regulatory, and expand business development. George now coordinates all technical aspects of Pharmako with a keen interest in Connect with George Website: www.pharmako.com.au Shownotes and references available on your local Designs for health website www.designsforhealth.com.au Register as a Designs for Health Practitioner and discover quality practitioner-only supplements at www.designsforhealth.com.au Follow us on Socials Instagram: Designsforhealthaus Facebook: Designsforhealthaus DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health
Miami, Florida--(Newsfile Corp. - November 24, 2022) - Rho Nutrition, which leverages liposomal technology to aid in the absorption of its vitamins by the human body, has announced the online launch of its products. Co-founded in 2022 by Ryan Bishop and George Padilla, the company offers supplements and sprays for a variety of problems, including immunity, healthy skin, antioxidants, heart health, and insomnia. "We are excited about the rollout of Rho Nutrition, as it represents our commitment to offering consumers vitamins that were made for them, not for profit," says Ryan. "George and I both worked in the supplement industry for many years and witnessed the issues that were prevalent, including a lack of quality ingredients and low absorption rates. To address these problems, we leveraged our expertise and the best suppliers of innovative technology, who helped us to use liposomes to potentially increase the absorption rate of vitamins." George explains that liposomes guard vitamins against stomach acids and then transport them to different tissues in the body. "They basically act as bodyguards for supplements, resulting in up to 8-10 times more absorption. It is the first significant innovation in the industry in nearly thirty years," he says. The supplements offered by Rho Nutrition focus on four primary ingredients and are taken in a flavored liquid form, which can be taken on its own by the teaspoon or added to water, juice, or a smoothie. The company's Sleep Mist is sprayed directly into the mouth. While Rho Nutrition is focused on the launch of its online products, the company is in talks with vitamin clinics and independent pharmacies about offering its supplements in stores. The company is also focused on bringing its products to consumers across the United States and Canada. "We hope to close out 2022 with strong online sales, as we are getting a lot of positive feedback from individuals who appreciate supplements that are backed by science," says Ryan. "In 2023, we plan to work hard to reach a wider market and make Rho Nutrition a company that is trusted because of its transparency and commitment to the proper absorption of vitamins." The supplements offered by Rho Nutrition were made by vitamin lovers for people who value health and wellness. The company uses liposomes to increase the absorption of its products, with the goals of helping individuals to feel more energized and to live fuller lives. For more information about Rho Nutrition or how liposomes aid in the absorption of supplements, please see the company's website or contact: Rho Nutrition (754) 231-3542 support@rhonutrition.com To view the source version of this press release, please visit https://www.newsfilecorp.com/release/145688
In this interview Dr. Blair discusses the value of liposome technology for the enhanced delivery of iron supplementation. Iron as a supplement is poorly absorbed and often cause gastric discomfort. Liposomes deliver nutrients in a form that is easy for the body to utilize resulting in better outcomes. Dr. Blair has been studying liposomes for the absorption of many nutrients. Some of the nutrients like iron are poorly absorbed while nutrients like glutathione are not absorbed orally at all. Liposome nutrients can be absorbed up to 17 times better than conventional forms. Dr. Blair has developed many liposomes and has numerous clinical studies that reveal the wonderful benefits offered by liposome nutrients. Much better absorption leads to better results. How do we know a supplement works? it is from the clinical research. When researching liposomes, it is possible to compare the blood levels of liposome vs conventional. The post 425 – Liposomes for Increasing Iron Absorption appeared first on Health Quest Podcast.
Liposomal technologyWhere the industry gets supplements rightWhere the industry gets them wrongFringe groupsImportance of third party testingCBD and beyond - what is the next big cannabinoid?What ingredients actually work?New pre-workout supplements?What Dr Vince looks for in ingredientsNewer stimulants on the marketBogus marketing claimsLactate as a supplementYou can reach Dr Vince by email: vince.krc@google.comThe Flex Diet Podcast is brought to you by the Flex Diet Certification. Go to https://flexdiet.com/ for 8 interventions on nutrition and recovery. The course will open again in January 2022.
Join Louise Hall, PMP as she queries Herman and Erich Bozenhardt, PE on the resurgence of liposomes in the wake of their role in COVID-19 vaccine and therapeutic development. The trio discuss how the technology has evolved, what we've learned, and what the future holds for the role of liposomes in biotherapeutic development moving forward.
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.Any guesses about today's episode? Today's conversation covers a very interesting and updated topic , something like Targeted Drug delivery. First and foremost I will define this system of drug delivery, then I will be making you aware of its two types. They are Passive drug targeting and active drug targeting. These are centred around nanoparticles and under these I will talk about magnetoliposomes. Later, I will be talking about different systems of drug targeting like ocuserts, progestaserts, liposomal drug delivery system, prodrugs, computerised miniature pumps.One by one I will be discussing all of these in different major heads like description, types, advantages, disadvantages, purpose and apt examples.This is how I will knit today's episode with different colored wool yarns to have a rainbow on my head and yours too, hope you really like it... For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!
Quercetin has quickly become one of the hottest-selling nutritional supplements in recent history. And rightfully so. It's a potent immune-supporting compound. However, quercetin offers more health benefits than immune-support alone. Find out why this flavonoid is so fabulous. What is quercetin? Quercetin is one of more than 4000 types of flavonoids found in plants. Flavonoids include many subcategories you've probably heard of but given little thought to: flavonesisoflavonesflavanoneschalcones Plants produce polyphenols as a defense against radiation and pathogens. When we eat or consume them, they play protective roles in our bodies too. The average person consumes about 14 mg of quercetin per day through their diet. It's found in a variety of plant foods, as shown in the table below. Food and Beverage Sources of QuercetinApplesBlack and green teaBlueberriesBroccoliBuckwheatCapersCherriesChokeberriesCilantroCitrus fruitsCranberriesCurly kaleDillGrapesLeeksLingonberriesLovageOnionsRed wineTeaTomatoes Quercetin Health Benefits Though quercetin offers numerous health benefits, once consumed, we don't absorb it very well. To derive the benefits I discuss here, you either need to eat loads of quercetin-containing foods or supplement with quercetin liposomes or phytosome, specific types of supplements designed to maximize absorption. Liposomes and phytosome surround quercetin in a lipid shell. Lipids pass from the digestive system into your circulation easily, so quercetin liposome and phytosome have much greater bioavailability than plain quercetin. Research shows quercetin phytosome increases blood levels by 20 times compared to plain non-phytosome versions of the supplement. Antioxidant support Free radicals are a natural part of life. Intense exercise, environmental toxins, smoking, stress, and poor nutrition accelerate free radical production. Antioxidants squelch free radicals before they can cause widespread damage to your cells. Quercetin seems to be one of the most potent antioxidants. Quercetin is a more potent antioxidant than other antioxidant nutrients, such as vitamin C, vitamin E, and β-carotene, and it can chelate transition metal ions, including iron.”Dong YS, et al. Research shows quercetin protects cells from some of the damage of cigarette smoking, though that doesn't negate the problems smoking causes. It might be helpful if you spend a lot of time in front of bonfires or campfires, too. Oxidative stress is also a known contributor to neurodegenerative diseases such as Alzheimer's or Parkinson's disease. Animal research shows the combination of quercetin and fish oil protects the brain from oxidative stress. Body composition improvement Animal research shows quercetin may prevent body fat gain when eating a higher-calorie, weight-gaining diet. In the study, animals ate a high-fat, high-calorie diet and took the supplement and showed an increase in their metabolic rates. The elevated metabolic rate may have offset the effects of the high-fat diet as they did not gain body fat. In overweight and obese humans, supplementation with 100 mg per day of quercetin over 12 weeks reduced body fat percentage and body mass index. In another study using 150 mg per day, people experienced a reduction in waist circumference and triglyceride levels. Cardiovascular health People with hypertension and with the ApoE3 gene took 150 mg per day of quercetin for six weeks. Their blood pressure decreased by 3.4 mmHg. That might not seem like a lot, but each 1 mmHg decrease is equal to a 2-3% reduction in cardiovascular disease risk on a population level. Endothelial cells line your blood vessels. When they become dysfunctional, the vessels don't relax and contract like they're supposed to. The rigid blood vessels become fragile, which leads to injury and inflammation. Quercetin helps relax blood vessels and enhances their function.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.12.336412v1?rss=1 Authors: Zhen, Y., Ewert, K. K., Fisher, W. S., Steffes, V. M., Li, Y., Safinya, C. R. Abstract: Lipid-based carriers of the hydrophobic drug paclitaxel (PTX) are used in clinical trials as next-generation agents for cancer chemotherapy. Improving the loading capacity of these carriers requires enhanced PTX solubilization. We compared the solubility of PTX in cationic liposomes (CLs) with lipid tails containing one (oleoyl; C18:1 {Delta}9 DOTAP/DOPC) or two (linoleoyl; C18:2 {Delta}9 DLinTAP/DLinPC) cis double bonds with newly synthesized cationic DLinTAP (2,3-dilinoleoyloxy-propyl-trimethyl-ammonium methylsufate). We used differential-interference-contrast microscopy to directly observe PTX crystal formation and generate kinetic phase diagrams representing the time-dependence of PTX solubility as a function of PTX content in the membrane. Replacing tails bearing one cis double bond (DO lipids) with those bearing two (DLin lipids) significantly increased PTX membrane solubility in CLs. Remarkably, 8 mol% PTX in DLinTAP/DLinPC CLs remained soluble for approximately as long as 3 mol% PTX (the membrane solubility limit which has been the focus of most previous fundamental studies and clinical trials) in DOTAP/DOPC CLs. The large increase in solubility is likely caused by enhanced molecular affinity between lipid tails and PTX upon replacement of oleoyl by linoleoyl tails, rather than by the transition in membrane structure from lipid bilayers to inverse cylindrical micelles observed in small-angle X-ray scattering. Importantly, the efficacy of PTX-loaded CLs against human prostate cancer (PC3) cells from measurements of the IC50 of PTX cytotoxicity was unaffected by changing the lipid tails, and toxicity of the CL carrier alone was negligible. Moreover, efficacy was approximately doubled against human melanoma (M21) cells for PTX-loaded DLinTAP/DLinPC over DOTAP/DOPC CLs. The findings demonstrate the potential of chemical modifications of the lipid tails to increase the PTX membrane loading well over the typically used 3 mol% while maintaining (and in some cases even increasing) the efficacy of CLs. The increased PTX solubility will aid the development of liposomal PTX carriers that require significantly less lipid to deliver a given amount of PTX, reducing side effects and costs. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.09.242693v1?rss=1 Authors: Khattak, M. I. K., Ahmed, N., Umer, M. F., Riaz, A., Ahmad, N. M., Khan, G. M. Abstract: Intricate formulation methods and/or use of sophisticated equipment limit the prevalence of liposomal dosage-forms. Simple techniques are developed to assemble amphiphiles into globular lamellae while transiting from immiscible organic to the aqueous phase. Various parameters are optimized by injecting chloroform solution of amphiphiles into the aqueous phase and subsequent removal of the organic phase. Further simplification is achieved by reorienting amphiphiles through a spontaneous phase transition in a swirling biphasic system during evaporation of the organic phase under vacuum. Although the chloroform injection yields smaller size and PDI yet spontaneous phase transition method overrides simplicity and productivity. The size distribution of liposomes and solid/solvent ratio in both or any phases of formulation show direct relation. Surface charge dependant large unilamellar vesicles with a narrow distribution have PDI
Not all vitamin C is created equal. To get the most from this awesome nutrient, you need to absorb as much as you can, and what you absorb needs to get into your cells. Only a fraction of the total amount of vitamin C gets into your bloodstream with IV and regular vitamin C supplements. Liposomes are superior in this regard. They allow more vitamin C to be absorbed and distributed throughout the cells in your body.Doug Cook RD www.dougcookrd.comTwitter: https://twitter.com/DougCookRDFacebook: https://www.facebook.com/dougcookrd/ Instagram: https://www.instagram.com/brain.health.nutritionist/ Support the show (https://www.buymeacoffee.com/dougcook)AOR Supplements Transform health through evidence-based, natural, and therapeutic products by AORDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.
Liposomes have benefits, but their production complexity, “shell” deterioration, and particle size variability and distribution make them a production nightmare that is often more of an art than a science. On this episode, Herman and Erich uncover the resurrection of the liposome and offer guidance on its use.
Vincent, Kathy and Rich discuss COVID-19 research paper overload, Moderna's mRNA vaccine Phase I results, increase of ACE2 RNA by cigarette smoke, and answer listener questions. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Drowning in COVID-19 papers (Science) CORD-19 2019 NCRC AI powered literature review SciSight Graphical guide to CoV vaccines (Nature) Moderna Phase I results Liposomes and lipid nanoparticles (Exelead) Cigarette smoke increases ACE2 (Dev Cell) Letters read on TWiV 616 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv
Vincent, Kathy and Rich discuss COVID-19 research paper overload, Moderna's mRNA vaccine Phase I results, increase of ACE2 RNA by cigarette smoke, and answer listener questions. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Drowning in COVID-19 papers (Science) CORD-19 2019 NCRC AI powered literature review SciSight Graphical guide to CoV vaccines (Nature) Moderna Phase I results Liposomes and lipid nanoparticles (Exelead) Cigarette smoke increases ACE2 (Dev Cell) Letters read on TWiV 616 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv
Histoire de l'utilisation des Liposomes en Cosmétique.
As it starts to get colder outside, sicknesses start to become more common. This is not due to the decrease in temperature, but is likely due to the increased time spent indoors and close to people who may be sick. Couple that with the decrease in vitamin D levels from less sunshine, and you can see why rates of sickness tend to go up during this time of year. In this week's episode, we'll discuss some winter essentials that may help improve the health of your immune system. Some things that may help impove immune system function include: Regular exerciseSupplementing with vitamin CDrink plenty of waterWash your hands oftenEat plenty of fruits and vegetablesGet enough sleep each nightPractice stress-reducing techniques Practicing these habits daily can help you be healthier any time of year, and with the new year coming up, you could try adding some of these to your New Year's resolution. Products Mentioned in Today's Show Liposomal C - Liposomal Vitamin C provides this key foundational nutrient formulated with liposomal technology. Liposomes are spheres made of phospholipids—the primary building blocks of cell membranes. Owing to this structure, liposomes bond easily with cell membranes to facilitate intracellular delivery of their nutrient cargo.Immune Essentials - Immune Essentials supports immune health with a blend of highly researched and effectively concentrated mushroom extracts combined with the polyphenol nutrient support of green tea.† This formula provides beta 1,3/1,6 d-glucan and a range of bioactive compounds that have been shown to potentiate immune response.† Grown in the USA under rigidly controlled conditions, these mushroom extracts are made with 100% certified organic ingredients. You can also listen to Winter Essentials for Health on our YouTube channel here.
Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr. Manabu Kinoshita, Associate Professor of Immunology, Department of Immunology and Microbiology, at the National Defense Medical College in Tokorozawa, Saitama, Japan. Blood Transfusions Today the ideaXme show is going to travel around the world to Japan, to discuss the topic of artificial blood technology. Blood transfusions save lives and improve health, but many patients requiring transfusion in 2019 still do not have timely access to safe blood. The need for blood transfusion may arise at any time in both urban and rural areas. The unavailability of blood has led to deaths and many patients suffering from ill-health. Blood loss from traumatic injuries is responsible for thousands of deaths annually, and even when people survive, oxygen depletion can leave tissue permanently injured. Fresh blood can only be stored for 42 days, and only lasts for a few hours un-refrigerated. Currently, if you need to receive a blood transfusion, it must also be matched specifically with your blood type or the "universal donor," type, O negative. An adequate and reliable supply of safe blood is normally assured by a stable base of regular, voluntary, unpaid blood donors, and they are also the safest group of donors as the prevalence of blood-borne infections is lowest among these donors. The World Health Organization (WHO) estimates that around 120 million units of donated blood are collected globally every year. 42% of these blood donations are collected in high-income countries, home to less than 16% of the world's population. Blood Substitute A blood substitute (also called artificial blood or blood surrogate) is any substance that can be used to mimic and fulfill some functions of biological blood. It aims to provide an alternative to blood transfusion, which is transferring blood or blood-based products from one person into another. Thus far, there are no well-accepted oxygen-carrying blood substitutes, which is the typical objective of a red blood cell transfusion; however, there are widely available non-blood volume expanders for cases where only volume restoration is required. A full substitute could be vital in settings like battlefields or rural areas without easy access to blood, used as a stopgap measure to keep the injured alive until they get to a hospital. Also, a one-size-fits-all blood substitute would overcome all sorts of existing obstacles, ranging from not enough donations by ethnic minorities, to finding matches for rare blood types. Dr. Manabu Kinoshita Today's guest joining us to go further into this topic, to discuss the challenges and possibilities of achieving a universal blood substitute, is Dr. Manabu Kinoshita, Associate Professor of Immunology, Department of Immunology and Microbiology, at the National Defense Medical College in Tokorozawa, Saitama, Japan. Dr. Kinoshita is a surgeon who specializes in both immunology (with a focus on host-defense dynamics against surgical stress) as well as nano-medicine, including red blood cell substitutes, platelet substitutes, and nanosheets for Biological Applications such as wound healing. The National Defense Medical College is Japan's six-year university-level military academy under control of the Ministry of Defense whose objectives are to train future military officers who are also medical doctors and current military doctors. Students graduate with an advanced level of theory and application of medical sciences required to conduct the missions of the Japan Self-Defense Forces and acquisition of research capability of the related fields as well as to offer training of clinical medicine. On this who we will hear from Dr. Kinoshita: About his background and interest in surgery, trauma, and the focus on artificial blood substitutes. An introduction to the work of the National Defense Medical College. His recent work and discoveries about his artificial blood product, profiled in the Journal of Transfusion paper entitled Combination Therapy Using Brinogen-chain peptide-coated, ADP-encapsulated Liposomes and Hemoglobin Vesicles for Trauma-induced Massive Hemorrhage in Thrombocytopenic Rabbits. His future visions for the project, and other research projects he is working on. For all the relevant links for this interview please visit www.radioideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.
Your Functional rx Podcast Episode 7 | What are liposomes and what do they do? This week Josh Rimany talks about liposomes and how they are now being utilized in the supplement industry to help speed up and improve the deliverability of certain hard to absorb supplements. One of the supplements that Josh has seen the biggest impact from switching over to a liposomal deliverability is CBD oil. The fat soluble liposomes help the CBD oil absorb more efficiently and, in turn, deliver better results. If you'd like more information, check out our blog at https://www.dilworthfunctionalwellness.com
Most people know by now that our environment, water, and food supply is chock full of toxins, and that our bodies accumulate these toxins over time, and this eventually leads to chronic disease and even early death. But what is the most effective way to both detox our bodies, and provide them with the much-needed nutrients missing from much of our modern, industrialized food system? How much time and energy have you wasted trying the latest detox protocol, without really knowing if it worked? How much money have you wasted on supplements over the years? How many times have you heard the hype about some new pill or powder, made it part of your routine, and then just kinda felt the same? That’s because not all supplements are made equally – not even close. Even when the supplement is full of high-quality nutrients, our body’s digestive system usually filters it out or breaks it down. But here’s the thing: our bodies desperately need supplements these days because we have pretty much destroyed the nutritional quality of our food system – and as a result of the same broken industrial systems, our bodies are also full of more toxins than they can handle while nutrient deprived. Today’s guest, however, is constantly striving to evolve the way the medical industry delivers care, and he is perpetually broadening the way the world understands health. Dr. Chris Shade is the creator of Quicksilver Scientific, an organization on a mission to combine nature’s nutrients with the power of science to deliver the most effective supplements and detoxification protocols on the market. Dr. Shade’s holistic mission began after he developed a new diagnostic process to analyze human toxicity, especially mercury. This proved there was, indeed, a toxicity problem in many communities – but he also needed a solution. So he developed a new nanoparticle biodelivery system that uses these microscopic spheres called Liposomes to deliver compounds such as glutathione directly into human cells, kickstarting our natural detoxification processes and improving cellular health. This is medical innovation inspired by nature and I’m into it. Topics Discussed In This Episode: How our body naturally detoxes itself, when the system is working Why Dr. Shade was dissatisfied with other products on the market & decided to make them himself What mercury can do to your body Why a liposomal delivery system is the most effective way of getting nutrients into your body (without destroying them) What you will learn from Quicksilver’s next-level toxicity test How leaded gasoline was related to violent crime Some game-changing info about Keto Where you are accumulating the most toxins in your daily life Why infrared saunas are beneficial for detox, beyond just sweating The best supplements for travel What lesser-known-but-vital nutrients you probably don’t have enough of The danger of armchair scientists & how junk science gets perpetuated online More about this episode. Connect with Luke on social media to learn how to take your lifestyle to the next level, plus catch exclusive live interviews & events: INSTAGRAM - @lukestorey // https://www.instagram.com/lukestorey/ FACEBOOK - https://www.facebook.com/MrLukeStorey/ TWITTER - @MrLukeStorey // https://twitter.com/MRLUKESTOREY YOUTUBE - https://www.youtube.com/c/LukeStorey THIS SHOW IS BROUGHT TO YOU BY: ORGANIFI. I'm loving Organifi Gold, especially for my night time routine. It has turmeric, ginger, reishi, lemon balm, turkey tail and other rad superfoods, phytonutrients & pain-soothing herbs. My daily routine lately goes like this: in the morning I add it to my nut milk smoothie. At night when I want to chill out, I make a golden latte. I add the power and a healthy fat like ghee, coconut, or grass-fed butter to hot water and voilá! Great warm elixir, really chills you out, gently detoxifies and tastes awesome. Save 20% using code “LIFESTYLIST” at organifi.com/luke. AND... ONDA WELLNESS. If you’re a discerning health enthusiast like myself, you’ve probably sat and scratched your head at the health food store trying to figure out which CBD product you should buy. They all make big claims, they all say they’re the best, but what actually works? Well, I just found a brand that I’m super stoked about, and I want to share it with you: ONDA offers a patented and truly full-spectrum line of products that aren’t dependent on the use of alcohol, CO2, or other solvents for extraction – and this is important because when you’re getting the medicine out of the plant, you don’t want to add poisons to it! You can try it for yourself and get 15% off using code LUKE15 at ondawellness.com. AND… BLUBLOX. Studies have clearly shown that blue and green light up to 550nm is a potent suppressor of melatonin, but the Sleep+ lenses in BLUblox glasses are the most effective blue and green light blockers for after dark use, proven to block 100% of the light in this range. BLUblox offers free global shipping everywhere, and they do prescription glasses, reading glasses, and non-prescription glasses for a tremendous value. Use code LIFESTYLIST for 15% off at BLUblox.com. HELP SUPPORT THIS SHOW! Starting and growing a podcast requires a ton of time, energy, and money. Do you appreciate this information, and want to support my mission to deliver as much life enhancing information as possible to as many people as possible? The easiest, and most effective way you can help is to do this: Go to Lukestorey.com/support and donate towards show production costs Subscribe to the show by clicking “subscribe” in iTunes Write us a review in iTunes Share this show with one friend right now You’d be amazed how much these four simple steps do to help us grow! Here’s the magic link for reviews in iTunes. Or, if you want to get there yourself, you can follow these instructions. Thank you from the bottom of my heart for listening and joining me on this journey we call life
Are you confused about CBD? If not, perhaps you should be. There are so many aspects to the CBD story that it is easy to be confused and difficult for the average consumers to know what to believe. A lot of what people think about CBD might be wrong or at least misunderstood. And that’s just if we consider the science of CBD. When one looks into the marketplace of CBD, it appears to be a wild west stampede into the unknown. CBD is an approved drug by FDA and is also being sold in food and supplements. The post 314 – CBD Liposomes Provide Up to 10 Times Better Absorption appeared first on Health Quest Podcast.
Why You Should Listen: In this episode, you will learn about liposomes, detoxification, and the role of detoxification in regaining health. About My Guest: My guest for this episode is Dr. Chris Shade. Dr. Chris Shade, PhD is a globally recognized expert on mercury and liposomal delivery systems. He has lectured and trained doctors in the U.S. and internationally on the subject of mercury, heavy metals, and the human detoxification system. Dr. Shade developed the patented liquid chromatographic mercury speciation technology used at Quicksilver Scientific while conducting his PhD dissertation work with advisor Robert Hudson at the University of Illinois at Urbana-Champaign. This technology was used to create the Mercury Tri-Test used today. Dr. Shade's current focus is on the development of cutting-edge, lipid-based delivery systems for nutraceuticals, such as liposomes and micro-emulsion systems to address the growing need of high quality, affordable detoxification solutions. Dr. Shade has a diverse spectrum of interests and experiences, ranging from traditional Scottish stone masonry and geology to open-ocean sailing and marine chemistry. Key Takeaways: - What is the role of liposomal and nano-emulsion technologies in nutritional products? - What testing is offered for heavy metals through QuickSilver Scientific? - Why does the Tri-Test look at urine, hair, and blood in evaluating mercury toxicity? - What is Phase 3 or the transport phase of detoxification? - What is the connection between detoxification and inflammation? - Does allergy or sensitivity to a substance make it more difficult to detoxify? - How does toxicity lead to a Th2 shift and this more allergy and inflammation and less microbial response? - What is the role of leaky gut in inflammation and reduced detoxification capacity? - How do toxins lead to anxiety? - Why are trace minerals a key aspect of detoxification? - What is the push/catch method of detoxification? - How does one detoxify aluminum, glyphosate, and gadolinium? - What other tools may be helpful in the realm of detoxification? Connect With My Guest: http://www.quicksilverscientific.com Interview Date: January 26, 2018 Disclaimer: The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority.
Liposomes are basically a nutrient wrapped in a layer of fat (phosphatidylcholine, an important beneficial fat molecule). This is the same way that nutrition is delivered to babies through breast milk. Little fat bubbles fulled with nutrients. Liposomes are sometimes used with drugs to deliver drugs to specific targets in the body. Liposomes are also used to deliver nutrients into the body. Liposomes are better at carrying nutrients into the body and also delivering that nutrient into the cell than powders which make up most tablets and capsules. The phosphatidylcholine part of the liposome is then added as a healthy fat to cell membranes. These are important distinctions in the delivery system that determine how well your supplements are absorbed and utilized. The post 262 – The Future of Liposome Nutrition – My Interview with Emek Blair appeared first on Health Quest Podcast.
“Properly utilised, Vitamin C could very easily displace or eliminate over 50% of prescription medication...and Vitamin C will never fail you if you take enough of it, in enough forms.” - Dr. Thomas Levy. Dr. Thomas Levy is the author of books like Stop America’s #1 Killer, Primal Panacea, Death By Calcium, Curing the Incurable: Vitamin C, Infectious Diseases, and Toxins. He also runs a great website called Peak Energy (www.peakenergy.com). I had a great conversation with him about a wide array of topics. He’s a board certified cardiologist but he no longer practices. Most of his time is taken up by research, writing, speaking and performing interviews like this one with us today! He holds so many degrees in different areas if I wrote them all down I’d still be here next week. In today’s episode we cover all things Vitamin C. We discuss the best forms of Vitamin C to take, what a liposome is, and how Vitamin C can help every ailment and disease known to man. We then delved into detoxification and how as an MD if can be hard to recommend natural and alternative protocols, and the effects of doing so on your career, reputation and business. Then we cover chronic infectious diseases and also the connection between infected teeth and heart disease, and discussed how studies published in the medical journals get ignored compared to those printed books. This was a pleasure to talk to Dr. Levy. I hope you enjoy the interview as much as I did. If you found it beneficial in anyway please share it with your friends and family. I would greatly appreciate that! Here is Dr. Thomas Levy’s website: www.peakenergy.com Health & Happiness Ryan
Dr Christopher Shade may well be one of the world's foremost experts in human detoxification. In today's podcast, Dr Shade takes us through the science behind liposomal technology and its applications in heavy metal detoxification. Find out the intricacies of liposomal formulation, stability and pharmacodynamics as well as the many possibilities for drug and nutrient delivery. Ahead of his appearance at the forthcoming 5th BioCeuticals Research Symposium, Dr Shade also shares some insight into the features of his masterclass - understanding of the complex biochemistry that underlies the moderation and removal of heavy metals and other biotoxins from overloaded systems . *****DISCLAIMER: The information provided on FX Medicine is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.*****
Episode 73 -10 Best Ingredients Ever Used in Skincare Products In this podcast episode with a difference you will learn the names of 10 ingredients that will benefit your skin’s health! Simply hit the play button and find out about 10 marvellous skincare ingredients listed below. Skin Therapist Nicola explains each ingredient, what it does and how clever it is for your remarkable skin! Don’t miss this one! Skin Therapist Nicola’s 10 Best Ingredients ever used: Melanoxyl for brightening your skin. This can be found in Guinot’s Newhite Range www.jerseybeautycompany.co.uk/guinot/newhite- brightening Vitamin C is a wonder ingredient for skin lightening and firming – find out why by listening to this podcast episode and learn all the ways that Guinot skincare use vitamin C. Guinot’s Sebocidine complex regulates oil production, mattifies skin and is amazing for you if you have oily skin. Try it in Guniot’s Masque Soin Pur Equilibre www.jerseybeautycompany.co.uk/guinot/masque-soin- pur-equilibre Hyaluronic acid is an incredible ingredient for dehydrated skin and can hold up to 1000 times it’s own weight in water. Guinot’s Hydracite complex stems from science research and is brilliant at putting moisture back in to skin that feels dehydrated. Liposomes are man made carriers that are smaller in size that a skins cell. Listen up as Skin Therapist, Nicola, explains why liposomes can travel at a deeper level, within the heart of your skin cells. Ultimately, liposomes are incredible for delivering the right active ingredients where you need them most. Ceramides are crucial for dry skin sufferers, find out why as our Skin Therapist reveals all in this podcast episode! Essential oils are also fabulous for dry skin. Find rosemary, thyme and lavender in Guinot’s Crème Nutrition Confort www.jerseybeautycompany.co.uk/guinot/creme-nutrition- confort Vitamin E has made it as number 9 in our skin therapist’s best ingredients – this is because Vitamin E has an anti free radical action, it protects airborne molecules from damaging your skin’s structure and causing wrinkles to appear. Veinoderm is a Guinot complex designed to treat redness. Containing arnica and horse chestnut, this ingredient is soothing and will care for the most delicate skin!
Liposomes are basically a nutrient wrapped in a layer of fat (phosphatidylcholine, an important beneficial fat molecule). This is the same way that nutrition is delivered to babies through breast milk. Little fat bubbles fulled with nutrients. Liposomes are sometimes used with drugs to deliver drugs to specific targets in the body. Liposomes are also used to deliver nutrients into the body. Liposomes are better at carrying nutrients into the body and also delivering that nutrient into the cell than powders which make up most tablets and capsules. The phosphatidylcholine part of the liposome is then added as a healthy fat to cell membranes. These are important distinctions that determine how well your supplements are absorbed and utilized. The post 195 – Liposomes for Nutrient Delivery – My Interview with Dr. Emek Blair appeared first on Health Quest Podcast.
An equilibrium phase belonging to the family of bilayer liposomes in ternary mixtures of dimyristoylphosphatidylcholine (DMPC), water, and geraniol (a biological alcohol derived from oil-soluble vitamins that acts as a cosurfactant) has been identified. Electron and optical microscopy reveal the phase, labeled Ltv, to be composed of highly entangled tubular vesicles. In situ x-ray diffraction confirms that the tubule walls are multilamellar with the lipids in the chain-melted state. Macroscopic observations show that the Ltv phase coexists with the well-known L4 phase of spherical vesicles and a bulk L alpha phase. However, the defining characteristic of the Ltv phase is the Weissenberg rod climbing effect under shear, which results from its polymer-like entangled microstructure.
The high fluorescent potential and the exceptional photostability of lipophilic derivatives of perylene-3,4:9,10-bis(dicarboximides) are utilized for the fluorescence-labelling of liposomes. The preparation of the liposomes is affected by supersonic starting from a lipid mixture consisting of the matrix lipids soy lecithin, cholesterol, -tocopherol and the perylene dyes. From a multitude of perylene derivatives investigated only those are optimally incorporated inot the bilayer membrane of unilamellar liposomes which are substituted at both nitrogen atoms by one or two linear hydrocarbon groups. In order to attain an optimal fluorescent quantum yield, about 200 to 300 dye molecules can be incorporated per liposome. The liposomes thus obtained have a diameter of about 70 to 80 nm, are homogeneous and may be stored for more than seven months. Neither the fluorescent properties nor the stability of these liposomes are influenced by the additional incorporation of various ara C-derivatives and lipophilic anchor groups which subsequently enable the coupling of antibodies to the liposomes. As the water-insoluble perylene dyes are incorporated into the bilayer membrane, the aqueous inner volume of the liposomes remains available for a fruther utilization.
Wed, 1 Jan 1992 12:00:00 +0100 http://epub.ub.uni-muenchen.de/4037/ http://epub.ub.uni-muenchen.de/4037/1/016.pdf Oberhauser, Berndt; Wagner, Ernst Oberhauser, Berndt und Wagner, Ernst (1992): Effective incorporation of 2'-O-methyl-oligoribonucleotides into liposomes and enhanced cell association through modification with thiocholesterol. In: Nucleic Acids Resarch, Vol. 20
Secretory vesicles isolated from adrenal medulla were found to fuse in vitro in response to incubation with Ca2+. Intervesicular fusion was detected by electron microscopy and was indicated by the appearance of twinned vesicles in freeze-fractured suspensions of vesicles and in thin-sectioned pellet. Two types of fusion could be distinguished: Type I, occurring between 10−7 M and 10−4 M Ca2+, was specific for Ca2+, was inhibited by other divalent cations and was abolished by pretreatment of vesicles with glutaraldehyde, neuraminidase or trypsin. Fusion type I was linear with temperature. A second type of intervesicular fusion was elicited by Ca2+ in concentrations higher than 2.5 mM and was morphologically characterized by multiple fusions of secretory vesicles. This type of fusion was found to be similar to fusion of liposomes prepared from the membrane lipids of adrenal medullary secretory vesicles: Ca2+ could be replaced by other divalent cations, the effect of different divalent cations was additive and pretreatments attacking membrane proteins were ineffective. Fusion type II of intact secretory vesicles as well as liposome fusion was discontinuous with temperature. Liposome fusion could be detected within 35 ms and persisted for 180 min. Using liposomes containing defined Ca2+ concentrations we have not found a major influence of Ca2+ asymmetry on fusion. Incorporation of the ganglioside GM3, which is present in the membranes of intact adrenal medullary secretory vesicles did not change the properties of liposomes fusion. Using a Ca2+-selective electrode we have identified in secretory vesicle membranes both high affinity binding sites for Ca2+ (Kd = 1.6 · 10−6M) and low affinity sites (Kd = 1.2 · 10−4M).