Podcasts about bioquark

Playing with the dead is often a nightmare waiting to happen. The Medical Industrial Complex has plans to map the brain and revive it, hours after the body has died. The company, BioQuark, was approved to begin experiments with family permission on clinically brain-dead patients and attempt to reanimate or bring them back to life and possibly stimulate their brain cells to regenerate themselves. Do we see this as ethical? Does this push the boundaries of science into playing God or is it all Frankenscience that needs to be monitored? Some argue that this is just one step forward in our evolution or perhaps it nullifies the concept of survival of the fittest. Tonight on Ground Zero (7-10 pm, pacific time) Clyde Lewis talks with author, nurse, and Death Doula, Lynn Monet about THE BRAIN THAT WOULDN'T DIE.Originally Broadcast On 10/24/24

Playing with the dead is often a nightmare waiting to happen. The Medical Industrial Complex has plans to map the brain and revive it, hours after the body has died. The company, BioQuark, was approved to begin experiments with family permission on clinically brain-dead patients and attempt to reanimate or bring them back to life and possibly stimulate their brain cells to regenerate themselves. Do we see this as ethical? Does this push the boundaries of science into playing God or is it all Frankenscience that needs to be monitored? Some argue that this is just one step forward in our evolution or perhaps it nullifies the concept of survival of the fittest. Tonight on Ground Zero (7-10 pm, pacific time) Clyde Lewis talks with author, nurse, and Death Doula, Lynn Monet about THE BRAIN THAT WOULDN'T DIE. Listen Live: https://groundzero.radio Archived Shows: https://aftermath.media

In dieser Podcastepisode stellt sich Ira Pastor und sein Unternehmen "Bioquark" einer wirklich interessanten Frage: Werden wir den Tod überwinden?Ihre Arbeit konzentriert sich dabei auf die sogenannten 3 R's – Regeneration, Reversion von Krankheiten und Revitalisierung/Verjüngung bei altersbedingten Leiden – mit dem Ziel, eine bessere Zukunft für die Menschen zu ermöglichen. Komplexe Organregeneration, der Übergang von Krebs in eine Reihe von harmlos beherrschbaren Krankheiten und die Verwischung der Grenzen zwischen Leben und Tod – das alles sind für Ira Pastor keine bloßen Ideen mehr, sondern nahe Zukunft. Doch komplexe biologische Mechanismen erfordern viel mehr bio-pharmazeutische Interventionen.In seiner Rede betont er deshalb, wie viel Potential und Wissen in der Natur zu finden sind. Ira Pastor zeigt auf, dass neuere Forschungen vor diesem Hintergrund bereits völlig neue Wege beleuchten, wie nicht-menschliche Bioprodukte positiv auf die Gesundheit und das Wohlbefinden der Menschen einwirken können. So könnte die Umkehrung des Todes ein Ereignis sein, das uns noch vor der Umkehrung des menschlichen Alterns vor Augen geführt werden wird.______________________________________Wenn du mehr erfahren willst, besuche auch meine Website: https://janszky.de/?p und abonniere diesen Kanal.Hier geht's zum 2b AHEAD Zukunftskongress: https://zukunftskongress.2bahead.com/?pWerde zum Future-Me Member: https://janszky.de/futureme_membership?pSichere Dir jetzt Dein Geschenk auf: https://janszky.de/geschenk?p

 On this episode of Progress, Potential, and Possibilities, we are joined by Moisés Fuentes Rubio, Mexican pro boxer, WBO minimum weight title (2011 to 2013), WBO interim junior flyweight title (2013 to 2014), and who is currently making his professional comeback. We are also joined by Dr. Joel Osorio, the Founder of RegenerAge, a growing regenerative medical practice with locations in Mexico, specializing in a range of translational regenerative medical interventions including biologics, bio-electric devices, nutritional programs, functional foods, and one of his specialties is the burgeoning segment of regenerative sports medicine for elite athletes like Mr. Fuentes. English Translation of Mr. Fuentes Rubio responses can be found in the episode YouTube bio - https://www.youtube.com/watch?v=8eDfcdfrxTc

Ira Pastor, ideaXme life sciences ambassador and CEO Bioquark interviews Dr. Michelle Francl, the Frank B. Mallory Professor of Chemistry, at Bryn Mawr College, and an adjunct scholar of the Vatican Observatory. Ira Pastor comments: Today, we have another fascinating guest working at the intersection of cutting edge science and spirituality Dr. Michelle Francl is the Frank B. Mallory Professor of Chemistry, at Bryn Mawr College, a distinguished women’s college in the suburbs of Philadephia, as well as an adjunct scholar of the Vatican Observatory. Dr. Francl has a Ph.D. in chemistry from University of California, Irvine, did her post-doctoral research at Princeton University, and has taught physical chemistry, general chemistry, and mathematical modeling at Bryn Mawr College since 1986. In addition Dr. Francl has research interests in theoretical and computational chemistry, structures of topologically intriguing molecules (molecules with weird shapes), history and sociology of science, and the rhetoric of science. Dr. Francl is noted for developing new methodologies in computational chemistry, is on a list of the 1,000 most cited chemists, is a member of the editorial board for the Journal of Molecular Graphics and Modelling, is active in the American Chemical Society, and the author of "The Survival Guide for Physical Chemistry". In 1994, she was awarded the Christian R. and Mary F. Lindback Award by Bryn Mawr College for excellence in teaching. She currently writes for Nature Chemistry on a range of topics including science, culture and policy, and in April 2016, was named one of nine adjunct scholars of the Vatican Observatory. Dr. Francl was awarded the 2019 American Chemical Society's Philadelphia Section Award which recognizes an individual, "who, by conspicuous scientific achievement through research, has made important contributions to man's knowledge and thereby aided the public appreciation of the profession." Dr. Fancl also writes extensively on spirituality, and has many publications in print including, but not limited to: “Seeking the Face of God: The Lives and Discoveries of Catholic Scientists”, "Not By Bread Alone, Reflections on the Scriptures for Lent 2020", and the Forthcoming​ “Waiting in Joyful Hope, Daily Reflections for Advent and Christmas”, and blogs at her website on "Quantum Theology" On this episode we will hear from Dr. Francl about: - Her background - How she developed an interest in science, in chemistry, and in the computational chemistry of "weird" / quantum structures - An overview of her work in the areas of theoretical / computational / quantum chemistry, also known as "molecular quantum mechanics", a branch of chemistry focused on the application of quantum mechanics in physical models and experiments of chemical systems - - Her role at the Vatican Observatory, as an adjunct scholar, studying the chemistry and material science of meteorites and working with issues of faith and science, from both a historical and philosophical perspective. - An overview of her work in the area of Quantum Theology, drawing parallels between the behavior of subatomic particles and the essence of spirituality - - Her research on the "contemplative mind" in advancing our understanding of both science and spirituality Credits: Ira Pastor, ideaXme ambassador interview. Visit ideaXme www.radioideaxme.com Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme To discuss collaboration and or partnerships please contact the founder of ideaXme: andrea@ideaxme.com Find ideaXme across the internet including on iTunes, YouTube, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify, Amazon Podcasts and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and CEO of Bioquark, interviews Philip Lymbery, award winning author of books Farmageddon and Dead Zone and CEO of Compassion in World Farming. Ira Pastor Comments: Compassion in World Farming (CIWF)is a campaigning and lobbying animal welfare organization which campaigns against the live export of animals, certain methods of livestock slaughter, and all systems of factory farming. Philip Lymbery, founder of Compassion in World Farming: Philip Lymbery is the CEO of CIWF, as well as visiting professor at the University of Winchester, ornithologist, photographer, naturalist, self-confessed animal advocate, and award winning author of both Farmageddon: The True Cost of Cheap Meat (listed as one of The Times Writers Books of the Year) as well as Dead Zone: Where the Wild Things Were. Protecting Animals is about Protecting People and the Planet: Philip has played leading roles in many major animal welfare reforms, including the Europe-wide bans on veal crates for calves and barren battery cages for laying hens. Described as one of the food industry’s most influential people, he has spearheaded CIWF’s engagement work with over 800 food companies worldwide, leading to real improvements in the lives of more than a billion farm animals every year. World's First Extinction and Livestock Conference of 2017: It was also Philip’s vision to set up the world’s first extinction and livestock conference in London in October 2017, bringing together Compassion in World Farming and the World Wildlife Fund, supported by HRH Prince of Wales Charitable Foundation. Philip's awards include Recipient of the ‘Outstanding Campaign’ award by Brussels based Eurogroup for Animals and the 2015 ‘International Golden Dove’ peace prize in Rome. On this ideaXme episode we hear from Philip Lymbery about: His background and how he developed a passion for animal welfare and advocacy. The background of Compassion In World Farming and an overview of what constitutes factory farming. Factory farming connections to pandemics, zoonotic diseases, and antibiotic resistance / superbugs. Industrial agriculture and its connection to biodiversity destruction in locations like the Amazon rainforest. Technological solutions such as lab / stem cell grown meats and alternative / plant-based protein sources. Solutions on how to feed the growing population and how we can all make a difference by the food choices we make. Credits: Ira Pastor interview video, text, and audio. This interview is in American English. Visit ideaXme: www.radioideaxme.com Contact Andrea Macdonald, the founder and CEO of ideaXme andrea@ideaxme.com Follow Ira Pastor on Twitter:@IraSamuelPastor Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including on iTunes, YouTube, SoundCloud, Radio Public, Amazon Podcasts, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Season 4Ep 18Reanimation Who shall conceive the horrors of my secret toil, as I dabbled among the unhallowed damps of the grave, or tortured the living animal to animate the lifeless clay?- Dr. Victor Frankenstein     From mummies to zombies to the creature himself, Frankenstein's monster, the tales of reanimating the dead span thousands of years.  For many people Mary Shelly's Frankenstein is or was their introduction to the subject of reanimation. Mary Shelley's Frankenstein is a cautionary tale about the abuses of science — in particular, the potential pitfalls of screwing around with corpses and lightning. If you're not familiar with the story of Frankenstein then see yourself the hell out right now. Are they gone? Good fuck em. If there are any untrustworthy folks left that are still here even though they don't know the story, here's a recap. The actual title, which most of you probably don't know, is "Frankenstein; or, The Modern Prometheus''. Shelly began writing the story when she was 18. The first edition was published anonymously in 1818 when she was 20. It began as a short story that unfolded into a novel. Although later versions of the tale popularly have the creature (he is referred to as the Creature, and as we all should know, the creature isn't Frankenstein) he’s essentially sewn together from various bodies parts and reanimated during a science experiment using lightning, this is not how the creature was originally written and conceived. In the original novel the creature was also not a big dumb lumbering idiot as he is usually portrayed. In Shelley's original work, Victor Frankenstein discovers a previously unknown but elemental principle of life, and that insight allows him to develop a method to imbue vitality into inanimate matter, though the exact nature of the process is left largely ambiguous. After a great deal of hesitation in exercising this power, Frankenstein (that’s the doctor for you slower passengers) spends two years painstakingly constructing the creature's proportionally large body (one anatomical feature at a time, from raw materials supplied by "the dissecting room and the slaughter-house"), which he then brings to life using his unspecified process. All of that aside, and all the differences and nuances aside, the idea is the same, the goal of reanimation of dead or inanimate things. While Shelly may have written an early example of the concept, process, and consequences of reanimation, she was not the first to think of this concept. There were scientists and thinkers earlier than her dreaming up ideas of reanimating animals and even humans. Science behind reanimation Okay Jeff, bear with us here, it's gonna get a little nerdy from time to time. You've all heard the old saying, there's nothing sure in life but death and taxes, but what if death wasn’t such a sure thing? Scientists have been attempting to restore life to the dead for hundreds of years. People have used water, electricity, chemicals and other things to try and reanimate dead animals and people.        A basic example of reanimation using water could be that of the ever popular sea monkey! Sea monkeys are actually brine shrimp. Their dried eggs, sold in pet stores, contain embryos that will revive when put in salt water, hatch, swim about, grow to be a quarter-inch long and make good fish food. Another example is the tardigrade. It is so small -- the size of a sand grain -- that most people are unaware of its existence, yet several times a year it performs one of the most astonishing feats known to science. When there has been no rain for a long time and its habitat dries out, the little animal's body loses its own water, shriveling and curling into a wrinkled kernel. Without water, the animal plunges into a profound state of suspended animation. The creature stops eating or crawling. It does not breathe. Its internal organs shut down, no longer digesting food or sending signals through its nervous system. Even metabolic processes inside cells shut down -- the usually busy genes going dormant and the enzymes that normally carry out thousands of biochemical reactions every second cease to function. Its body dries to a crisp. So profound is the loss of activity that, according to a common textbook definition of life, which says metabolism is a hallmark of life, the little animal is… dead. And yet, after days or even months, if moisture returns, the animal soaks up the water and resumes all normal activities. The creature is informally called a water bear or, more formally, a tardigrade, which means "slow walker." On the evolutionary tree, it lies between worms and insects, one of the many small but remarkable life forms on Earth known almost solely to those who study biology. So there is one issue with these guys and others like them. There's an argument on whether they are truly being reanimated or if there is just some weird sort of hibernation going on. The chief hallmark of life, textbooks often say, is metabolism, the sum of all genetic and enzymatic processes that go on inside cells and in interactions among cells. If one accepts that definition, then an organism in suspended animation is not alive. That conclusion, however, raises a semantic problem because if it is not alive, it is dead. If so and if it revives, then life has been created, a phenomenon that would violate a cardinal principle of biology -- that complex life forms cannot be spontaneously generated but only come from living parents. To avoid this logical trap, the few biologists who have studied the phenomenon generally refer to it as cryptobiosis, meaning "hidden life." So strong, however, was the metabolism-centered view of life that until recently most biologists suspected that cryptobiotic organisms were not totally inactive. They argued that enough water remained inside the animals to permit metabolism to continue at a rate too slow to be detected. After all, they knew some higher animals can reduce their metabolic rates by hibernating in winter, and others enter a state of even lower metabolism, called estivation, that allows them to endure dry, summer heat. Cryptobiotic animals, many researchers suspected, were simply extending a familiar capacity to a previously unknown extreme. Recently, however, scientists have established that, although even the driest organisms retain a few water molecules, they constitute only a small fraction of the minimum needed for metabolism. For example, most of the workhorse molecules of metabolism, proteins, must be awakened in water to assume the shape essential to their functions as enzymes. Tardigrades and nematodes, like most animals, are normally 80 percent to 90 percent water. In the cryptobiotic state, the organisms contain only about 3 percent to 5 percent water. Under laboratory conditions, the water content of some has been reduced to 0.05 percent, and they were revived. Most authorities now agree that no metabolism occurs during cryptobiosis. The term no longer means "a hidden form of ordinary life" but rather "a state of being in which the active processes of life are temporarily suspended." In the cryptobiotic state, all that remains of a living organism is its structural integrity. A dry animal may be shrunken, but it maintains all connections that keep together the structures of its cells. In other words, biologists now hold, molecules hooked together in a certain way will metabolize if given water. Life is not the result of some mystical animating force that inhabits proteins or the nucleic acids that make up DNA. It is the structural arrangement of certain molecules that will behave chemically in specific ways in the presence of water. So what does that all mean? Fuck if we know. But essentially it seems that in these tiny organisms, if the law of the land is followed to a T, then it seems they are dead, dried, shriveled up things with no metabolisms, thus no life, that can actually be reanimated with water. Interesting indeed. There's a ton more cool info on this in an article from the Washington Post titled "Just Add Water" from 1996 that this information was taken from. If you're really into the science behind this stuff we definitely recommend this article!  Electricity Now if one were to think that Frankenstein, despite being an early foray into the world of reanimation, was possibly influenced by real world attempts at the same result, one would be correct. In the late 18th century many doctors and scientists began toying with dead things and electricity. In 1780, Italian anatomy professor Luigi Galvani discovered that he could make the muscles of a dead frog twitch and jerk with sparks of electricity. Others quickly began to experiment by applying electricity to other animals that quickly grew morbid. Galvani’s nephew, physicist Giovanni Aldini, obtained the body of an ox, proceeding to cut off the head and use electricity to twist its tongue. He sent such high levels of voltage through the diaphragm of the ox that it resulted in “a very strong action on the rectum, which even produced an expulsion of the feces,” Aldini wrote.     People outside of science were also fascinated by electricity. They would attend shows where bullheads and pigs were electrified, and watch public dissections at research institutions such as the Company of Surgeons in England, which later became the Royal College of Surgeons. When scientists tired of testing animals, they turned to corpses, particularly corpses of murderers. In 1751, England passed the Murder Act, which allowed the bodies of executed murderers to be used for experimentation. “The reasons the Murder Act came about were twofold: there weren’t enough bodies for anatomists, and it was seen as a further punishment for the murderer,” says Juliet Burba,  chief curator of an exhibit called “Mary and Her Monster” at the Bakken Museum in Minnesota. “It was considered additional punishment to have your body dissected.” On November 4, 1818, Scottish chemist Andrew Ure stood next to the lifeless corpse of an executed murderer, the man hanging by his neck at the gallows only minutes before. He was performing an anatomical research demonstration for a theater filled with curious students, anatomists, and doctors at the University of Glasgow. But this was no ordinary cadaver dissection. Ure held two metallic rods charged by a 270-plate voltaic battery to various nerves and watched in delight as the body convulsed, writhed, and shuddered in a grotesque dance of death. “When the one rod was applied to the slight incision in the tip of the forefinger,” Ure later described to the Glasgow Literary Society, “the fist being previously clenched, that finger extended instantly; and from the convulsive agitation of the arm, he seemed to point to the different spectators, some of whom thought he had come to life.” Ure is one of many scientists during the late 18th and 19th centuries who conducted crude experiments with galvanism—the stimulation of muscles with pulses of electrical current. The bright sparks and loud explosions made for stunning effects that lured in both scientists and artists, with this era of reanimation serving as inspiration for Mary Shelley’s literary masterpiece, Frankenstein; or, The Modern Prometheus. While most scientists were using galvanism to search for clues about life, Ure wanted to see if it could actually bring someone back from the dead. “This was a time when people were trying to understand the origin of life, when religion was losing some of its hold,” says Burba. “There was a lot of interest in the question: What is the essence that animates life? Could it be electricity?” Lying on Ure’s table was the muscular, athletic corpse of 35-year-old coal miner, Matthew Clydesdale. In August 1818, Clydesdale drunkenly murdered an 80-year-old miner with a coal pick and was sentenced to be hanged at the gallows. His body remained suspended and limp for nearly an hour, while a thief who had been executed next to Clydesdale at the same time convulsed violently for several moments after death. The blood was drained from the body for half an hour before the experiments began.Andrew Ure, who had little to no known experience with electricity, was a mere assistant to James Jeffray, an anatomy professor at the University of Glasgow. He had studied medicine at Glasgow University and served briefly as an army surgeon, but was otherwise known for teaching chemistry. “Not much is known about Ure, but he was sort of a minor figure in the history of science,” says Alex Boese, author of Elephants on Acid: And Other Bizarre Experiments. One of Ure’s main accomplishments was this single bizarre galvanic experiment, he says.   Others, such as Aldini, conducted similar experiments, but scholars write that Ure was convinced that electricity could restore life back into the dead. “While Aldini contented himself with the role of spasmodic puppeteer, Ure’s ambitions were well nigh Frankesteinian,” wrote Ulf Houe in Studies in Romanticism. Ure charged the battery with dilute nitric and sulphuric acids five minutes before the police delivered the body to the University of Glasgow’s anatomical theater. Incisions were made at the neck, hip, and heels, exposing different nerves that were jolted with the metallic rods. When Ure sent charges through Clydesdale’s diaphragm and saw his chest heave and fall, he wrote that “the success of it was truly wonderful.”Ure’s descriptions of the experiment are vivid. He poetically noted how the convulsive movements resembled “a violent shuddering from cold” and how the fingers “moved nimbly, like those of a violin performer.” Other passages, like this one about stimulating muscles in Clydesdale’s forehead and brow, are more macabre: “Every muscle in his countenance was simultaneously thrown into fearful action; rage, horror, despair, anguish, and ghastly smiles, united their hideous expression in the murderer’s face, surpassing far the wildest representations of a Fuseli or a Kean,” wrote Ure, comparing the result to the visage of tragic actor, Edmund Kean, and the fantastical works of romantic painter Henry Fuseli. He continued: “At this period several of the spectators were forced to leave the apartment from terror or sickness, and one gentleman fainted.” The whole experiment lasted about an hour. “Both Jeffray and Ure were quite deliberately intent on the restoration of life,” wrote F.L.M. Pattinson in the Scottish Medical Journal. But the reasons for the lack of success were thought to have little to do with the method: Ure concluded that if death was not caused by bodily injury there was a probability that life could have been restored. But, if the experiment succeeded it wouldn’t have been celebrated since he would be reviving a murderer, he wrote. Ure is just one of many scientists and doctors at this time experimenting with reanimation. We’ll discuss some others in a bit. In modern times a case can be made that we reanimate people all the time. Without getting into semantics of clinical death versus biological death versus this versus that blah blah, we can look to the use of a defibrillator as a basic use of electricity to revive a person who is technically dead. Would that not be reanimation? There are arguments being made and in  discussions about reanimation it seems like this usually comes up. Then there is a giant sciencey biology fight and much ink is spilled and pocket protectors destroyed and still no consensus.. so we'll spare you the agony of those arguments.  Electricity seems to be the most popular medium in historical attempts at resurrection, mostly because of its effects on muscles and the ability to move body parts after death. These days we know that this is simply a reflex action due to the stimulation of the muscles and nerves and has nothing to really do with reanimation so to speak. CHEMICAL So what about using chemicals? Can chemicals reanimate cells and bring the dead back to life? Well according to many zombie movies yes, but according to a Yale university study...also yes. Yale neuroscientist Nenad Sestan revealed that his team has successfully reanimated the brains of dead pigs recovered from a slaughterhouse. By pumping them with artificial blood using a system called BrainEx, they were able to bring them back to “life” for up to 36 hours. Also you heard that right… The call it fucking BrainEx. If that doesn't Scream B horror movie..I don't know what does. Admittedly, the pigs’ brains did not regain consciousness, but Sestan acknowledged that restoring awareness is a possibility. Crucially, he also disclosed that the technique could work on primate brains (which includes humans), and that the brains could be kept alive indefinitely. This is interesting because it raises some interesting questions. If consciousness could be restored to the brain if a human… Would it be worth it. What would it be like to just be a brain?  Even if your conscious brain were kept alive after your body had died, you would have to spend the foreseeable future as a disembodied “brain in a bucket”, locked away inside your own mind without access to the senses that allow us to experience and interact with the world and the inputs that our brains so crave. The knowledge and technology needed to implant your brain into a new body may be decades, if not centuries, away. So in the best case scenario, you would be spending your life with only your own thoughts for company. Some have argued that even with a fully functional body, immortality would be tedious. With absolutely no contact with external reality, it might just be a living hell.  According to some, it is impossible for a disembodied brain to house anything like a normal human mind. Antonio Damasio, a philosopher and neuroscientist, has pointed out that in ordinary humans, brain and body are in constant interaction with each other. Every muscle, nerve, joint and organ is connected to the brain – and vast numbers of chemical and electrical signals go back and forth between them each and every second. Without this constant “feedback loop” between brain and body, Damasio argues, ordinary experiences and thought are simply not possible. So what would it be like to be a disembodied brain? The truth is, nobody knows. But it is probable it would be worse than being simply tedious – it would likely be deeply disturbing. Experts have already warned that a man reportedly due to have the world’s first head transplant could suffer a terrible fate. They say his brain will be overwhelmed by the unfamiliar chemical and electrical signals sent to it by his new body, and it could send him mad. A disembodied brain would be likely to react similarly – but because it would be unable to signal its distress, or do anything to bring its suffering to an end, it would be even worse. So, to end up as a reanimated disembodied human brain may well be to suffer a fate worse than death. Now maybe if you had a body things wouldn't be so bad, but as stated earlier many think that it would be extremely tedious to live forever if it was possible. None of us expected to make it this long… Fuck living forever.  Another player in the chemical game actually is a mix of chemical and biological attempts at reanimating recently dead brains.  The company Bioquark, plans to initiate a study to see if a combination of stem cell and protein blend injections, electrical nerve stimulation, and laser therapy can reverse the effects of recent brain death. They're literally trying to bring people back from the dead. "It's our contention that there's no single magic bullet for this, so to start with a single magic bullet makes no sense. Hence why we have to take a different approach," Bioquark CEO, Ira Pastor, told Stat News. As Pastor told the Washington Post last year, he doesn't believe that brain death is necessarily a permanent condition, at least to start. It may well be curable, he argued, if the patient is administered the right combination of stimuli, ranging from stem cells to magnetic fields. The resuscitation process will not be a quick one, however. First, the newly dead person must receive an injection of stem cells derived from their own blood. Then doctors will inject a proprietary peptide blend called BQ-A into the patient's spinal column. This serum is supposed to help regrow neurons that had been damaged upon death. Finally, the patient undergoes 15 days of electrical nerve stimulation and transcranial laser therapy to instigate new neuron formation. During the trial, researchers will rely on EEG scans to monitor the patients for brain activity. Sometimes the dead come back on their own! Lazarus syndrome is the spontaneous return of a birthday cardiac rhythm after failed attempts at resuscitation. Its occurrence has been noted in medical literature at least 38 times since 1982. It takes its name from Lazarus who, as described in the New Testament, was raised from the dead by Jesus. Basically this occurs after a person has died and attempts to revive then using cpr or other means have failed and since time will pass and the heart will start back up on its own! The causes of this syndrome are not understood very well. With some hypotheticals being there build up of pressure on the chest following cpr, hyperkalemia (elevated potassium levels in the blood), or high doses of epinephrine. Some of these cases are pretty crazy. Is this spontaneous biological reanimation? Heres a few tales:  A 66-year-old man suffering from a suspected abdominal aneurysm suffered cardiac arrest and received chest compressions and defibrillation shocks for 17 minutes during treatment for his condition. Vital signs did not return; the patient was declared dead and resuscitation efforts ended. Ten minutes later, the surgeon felt a pulse. The aneurysm was successfully treated, and the patient fully recovered with no lasting physical or neurological problems.According to a 2002 article in the journal Forensic Science International, a 65-year-old prelingually deaf Japanese man was found unconscious in the foster home he lived in. CPR was attempted on the scene by home staff, emergency medical personnel and also in the emergency department of the hospital and included appropriate medications and defibrillation. He was declared dead after attempted resuscitation. However, a policeman found the person moving in the mortuary after 20 minutes. The patient survived for 4 more days.A 45-year-old woman in Colombia was pronounced dead, as there were no vital signs showing she was alive. Later, a funeral worker noticed the woman moving and alerted his co-worker that the woman should go back to the hospitalA 65-year-old man in Malaysia came back to life two-and-a-half hours after doctors at Seberang Jaya Hospital, Penang, pronounced him dead. He died three weeks later.Anthony Yahle, 37, in Bellbrook, Ohio, USA, was breathing abnormally at 4 a.m. on 5 August 2013, and could not be woken. After finding that Yahle had no pulse, first responders administered CPR and were able to retrieve a stable-enough heartbeat to transport him to the emergency room. Later that afternoon, he again suffered cardiac arrest for 45 minutes at Kettering Medical Center and was pronounced dead after all efforts to resuscitate him failed. When his son arrived at the hospital to visit his supposed-to-be deceased father, he noticed a heartbeat on the monitor that was still attached to his father. Resuscitation efforts were resumed, and Yahle was successfully revived.Walter Williams, 78, from Lexington, Mississippi, United States, was at home when his hospice nurse called a coroner who arrived and declared him dead at 9 p.m. on 26 February 2014. Once at a funeral home, he was found to be moving, possibly resuscitated by a defibrillator implanted in his chest.[11] The next day he was well enough to be talking with family, but died fifteen days later.And probably the craziest one: Velma Thomas, 59, of West Virginia, USA holds the record time for recovering from clinical death. In May 2008, Thomas went into cardiac arrest at her home. Medics were able to establish a faint pulse after eight minutes of CPR. Her heart stopped twice after arriving at the hospital and she was placed on life support. Doctors attempted to lower her body temperature to prevent additional brain injury. She was declared clinically dead for 17 hours after doctors failed to detect brain activity. Her son, Tim Thomas, stated that "her skin had already started hardening, her hands and toes were curling up, they were already drawn". She was taken off life support and funeral arrangements were in progress. However, ten minutes after being taken off life support, she revived and recovered. Again… Spontaneous biological reanimation? Who knows! So these are some of the concepts of reanimation. Let's talk about a couple people that were into the reanimation game: Lazzaro SpallanzaniSpallanzani was a Catholic priest, and a professor of natural history at Pavia University in the late 1700s. He started small, adding water to microscopic animals and announcing that he had managed a resurrection when they came to life. But he wasn't really satisfied. For some reason, Spallanzani turned for spiritual guidance to noted French cynic and atheist Voltaire. Spallanzani asked him what he thought happened to the souls of animals after death. Voltaire must have liked the guy, because he replied gently that he believed Spallanzani about the reanimation, and that the priest himself would be best qualified to answer the question. Although the priest's next trick was cutting the heads off snails to see if they'd grow back, he was definitely the least mad of the mad scientists. He was the first person to prove that chemicals inside the body helped with digestion, and was the first to spot white blood cells Andrew CrosseAndrew Crosse was messing around with lightning in 1837. He strung about a third of a mile of copper wire around his estate, and concentrated all the electricity it picked up in his laboratory. Specifically, he focused on a sterile dish of a primordial soup that he'd carefully prepared. After zapping the soup, he noticed that crystals were growing in it. Hoping he could graduate to something way cooler, he tried giving the soup long exposures to weak currents. To his amazement, he found that after long weeks, animals shaped like mites began to form, and then move around. He repeated the experiment again and again, and to modern readers it seems that he kept the environment pretty sterile if he followed all the procedures he described. Still, we have to assume it was contaminated. The Victorians assumed the same thing, but they also assumed that Crosse was a jerk. The scientists believed he was making a play for false glory. The theists assumed he was trying to play god. The neighbors just thought he was going to burn his, and subsequently their, house down. He was disliked by all and had to leave his estate, until the scandal cleared. Johann DippelThis was the actual guy who inspired the Frankenstein legend. He lived in the Frankenstein castle, and signed his name as Frankenstein. Surprisingly, he was less like the good doctor than most people think, since he was more interested in preserving life than reanimating it. He did rob graves in the area — or is said to have — but only because he wanted to mix up an elixir of immortality, and for some reason he thought buried corpse parts might do it for himMyThe Doggie ScientistsIn the first half of the 20th century, it was not a good time to be a dog. People were apt to, say, stick you in a tin can and send you into space. But at least, that way, you got to see something. You really didn't want to be in range of the doggie Frankensteins. Robert Cornish would suffocate dogs and attempt to bring them back to life via emergency medical measures. He actually managed to bring two back, although they sustained brain damage. Sergei Bryukhonenko attached his newly-invented heart and lung machine to a dog's head and kept it alive for quite some time, lying on a plate and eating and drinking. Giovanni AldiniNow this was a Frankenstein extraordinaire that we mentioned earlier. Having learned about how to use electricity to make the muscles of a corpse jump, he took it to the extreme in public. He zapped the heads of slaughtered oxen, in order to get them to twitch in front of audiences. He moved on to the heads of executed prisoners, applying the electrodes to the ears. He cut open corpses so he could zap their spinal cords. He claimed he could zap the suffocated and the drowned, in order to revive them completely. And he bragged that he could "command the vital powers." He also took a sideline into researching whether or not there was a way to make objects and people fireproof. Not much is said about his experiments in the latter area — but perhaps that's for the best. His tireless self-promotion never got him the chance to bring someone back to life, but it got him plenty of attention. He eventually traveled to Austria, where he was made a knight, and awarded a political position. Unlike many of the scientists on this list — and certainly unlike Frankenstein himself — Aldini died a rich and happy man. JAMES LOVELOCKIn the 1950s, the field of cryobiology was so new, it didn't even have a name yet, so budding cryobiologists didn't always have the exact tools they needed for a particular procedure. James Lovelock was one such scientist, and he outlined a method to bring rodents back to life.Lovelock's procedure involved putting a rat in a bath at minus 5 degrees Celsius for 90 minutes. After the rat was good and frozen, Lovelock would attempt to bring it back to life. Back then there weren't fancy lab tools like rat heart defibrillators, so Lovelock brought the rats' hearts back with a warm spoon.By restarting the heart, and gradually warming the body, Lovelock brought the mice back to life. Although we can't say that's what the mice would have wanted. One quick sidebar, is there a difference between resurrection and reanimation? The short answer is yes. As verbs the difference between resurrect and reanimate is that resurrect is to raise from the dead, to bring life back to while reanimate is to animate anew; to restore to animation or life; to infuse new life, vigor, spirit, or courage into; to revive; to reinvigorate; as, to reanimate a drowned person; to reanimate disheartened troops; to reanimate languid spirits. As an adjective reanimate is being animated again. Looking into it more than this leads to an exhaustive ordeal involving many many religious websites trying to explain why Jesus is not a zombie. Which is as ridiculous and hilarious as it sounds and is definitely recommended reading.  The subject of reanimation brings up many different facets of not only biology and chemistry but ethics as well. There are lines that are not meant to crossed, is this one? Would you want to be brought back from the dead? The lines between reanimation, resuscitation, and resurrection seem to be thin and sometimes vague. That's why there are such different topics being discussed in this episode.  Either way it's a hell of a trip!Now with all that being said we are bringing back an old favorite! We are talking top ten movies baby! Today is obviously the top ten movies about reanimation! This list is home to a wide variety of movies that some may consider reanimation related and some may not. But they all involved people coming back in some form.https://www.imdb.com/search/keyword/?keywords=reanimation Here's a top 8 list that's much better https://www.google.com/amp/s/io9.gizmodo.com/8-movies-featuring-reanimation-that-arent-about-zombie-1833752947/amp The Midnight Train Podcast is sponsored by VOUDOUX VODKA.www.voudoux.com Ace’s Depothttp://www.aces-depot.com BECOME A PRODUCER!http://www.patreon.com/themidnighttrainpodcast Find The Midnight Train Podcast:www.themidnighttrainpodcast.comwww.facebook.com/themidnighttrainpodcastwww.twitter.com/themidnighttrainpcwww.instagram.com/themidnighttrainpodcastwww.discord.com/themidnighttrainpodcastwww.tiktok.com/themidnighttrainp And wherever you listen to your favorite podcasts. Subscribe to our official YouTube channel:OUR YOUTUBE

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark interviews Dr. Frank D. Marks, MS, ScD, Director of Hurricane Research Division, at NOAA. Ira Pastor comments: Weather and climate disasters affect the world's population. The total approximate cost of damages from weather and climate disasters in the U.S. alone from 1980 to 2019, is over $1.75 trillion, and a major component of that damage results from hurricanes. Few things in nature can compare to the destructive force of a hurricane. Called the "Greatest Storm On Earth", a hurricane is capable of annihilating coastal areas with sustained winds of 155 miles per hour or higher, intense areas of rainfall, and a storm surge. In fact, during it's life cycle a hurricane can expend as much energy as 10,000 nuclear bombs! The National Oceanic and Atmospheric Administration (NOAA) is an American scientific agency, within the United States Department of Commerce, that focuses on the conditions of the oceans, major waterways, and the atmosphere. NOAA warns of dangerous weather, charts seas, guides the use and protection of ocean and coastal resources, and conducts research to provide the understanding and improve stewardship of the environment. Dr. Frank D. Marks, is Director of Hurricane Research Division, at NOAA: Dr. Marks is a recognized expert in tropical cyclones and is the leader of the NOAA tropical cyclone research efforts as the research lead of NOAA is Hurricane Forecast Improvement Project (HFIP) and the director of the Hurricane Research Division of NOAA Atlantic Oceanographic and Meteorology Laboratory. Dr. Marks also serves as co-lead of the NOAA Office of the Federal Coordinator for Meteorological Services and Supporting Research (OFCM) Working Group for Tropical Cyclone Research (WG/TCR). His research interests include analyzing meteorological remote sensing (e.g., microwave radar and radiometer) and numerical model data sets, particularly in tropical cyclones and mesoscale convective systems to understand the storm kinematic and precipitation structure. Besides his role within NOAA Dr. Marks is also an Adjunct Professor in the Department of Meteorology and Physical Oceanography at the University of Miami, as well as a Fellow of the Cooperative Institute for Marine and Atmospheric Studies (CIMAS) at the University of Miami Rosenstiel School for Marine and Atmospheric Sciences. Dr. Marks received a B.S. in Meteorology from Belknap College (1973) and both an M.S. (1975) and Sc.D. (1981) in Meteorology from the Massachusetts Institute of Technology (MIT). Dr. Marks is a member of the American Meteorlogical Society (AMS) and became a Fellow of the AMS in 2000. He served as a member of AMS Committee on Radar Meteorology and of the AMS Council. On this ideaXme episode we will hear from Dr. Marks about: - His background - how he became interested in science, in meteorology, in hurricane research, and a little bit of his career journey through the academic and government sectors to date - A general introduction to NOAA and specifically the Hurricane Research Division - A discussion of core research priorities of the Hurricane Research Division - Technological developments that Dr. Marks is personally most excited about looking forward over the next decade or two, such as artificial intelligence/ machine learning in the forecasting process - The SUSTAIN lab or the "Surge Structure Atmosphere Interaction" lab - University of Miami US$45 million initiative to produce hurricanes up to a category 5 level (the strongest there is), with wind speeds reaching more than 252 km/h (157 mph). - This history of NOAA attempts to "stop a hurricane in its track" and Project STORMFURY - His experiences with flying into a hurricane on the NOAA Hurricane Hunter aircrafts Credits: Ira Pastor, ideaXme ambassador interview. Visit ideaXme www.radioideaxme.com Contact the founder of ideaXme: andrea@ideaxme.com Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme To discuss collaboration and or partnerships please contact the founder of ideaXme: andrea@ideaxme.com Find ideaXme across the internet including on Apple Podcasts, SoundCloud,Radio Public,TuneIn Radio,I Heart Radio, Google Podcasts, Spotify, Amazon Podcasts and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark interviews Dr Vitaly Vanchurin, PhD, Associate Professor, Theoretical Physics and Cosmology, Swenson College of Science and Engineering, at the University of Minnesota (UMN). The Multiverse, Cosmological Neural Networks and "Space Noodles" Dr Vanchurin's big questions and the tools we need to answer them: "What is the origin of our Universe? What determines our vacuum and the cosmological constant that is responsible for the observed accelerated expansion of space? What determines the onset of structure formation and the birth of galaxies in our Universe? Our innate curiosity about our beginnings has been, since time immemorial, and still is, at the heart of every human being. This age old question of our origin can now be addressed by applying the scientific method". Ira Pastor comments: Today, we have a really exciting thought leader joining us on ideaXme who spends his time thinking about really BIG questions – Questions like: what is the origin of our Universe? What’s behind the cosmological constant (in Albert Einstein's field equations of general relativity) that is responsible accelerated expansion of space? What determines the onset of structure formation and the birth of galaxies in our Universe? And many other fascinating topics. Theoretical Physics and Cosmology Dr. Vitaly Vanchurin, is an Associate Professor, Theoretical Physics and Cosmology, Swenson College of Science and Engineering, at the University of Minnesota (UMN). Dr. Vanchurin has both a Masters, and Ph.D. in Physics, from Tufts Institute of Cosmology, and did his dissertation on the evolution of cosmic strings. Dr Vanchurin currently spends his time focused on a variety of themes including: cosmic inflation, multiverse cosmology, string theory landscapes, multi-dimensional fluids, gravitational waves, light propagation throughout the universe, and other quite esoteric concepts. Most recently Dr. Vanchurin has been in the scientific press quite a bit regarding a fascinating new theory on “cosmological neural networks”. On this episode we will hear from Dr. Vanchurin about: - His background - how he developed his interest in science, in theoretical physics, and in cosmology - His current research interests and programs at UMN - A discussion of his most recent research / theories in the area of "cosmological neural networks" and novel ideas surrounding machine learning - His views on the connection of his theories to those in the field of quantum biology (as well as thoughts on consciousness) - His work on multiverse theories and paradoxes - And of course "Space Noodles" This interview is in American English. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor Ira Pastor, ideaXme life sciences ambassador. Visit ideaXme here: www.radioideaxme.com If you enjoyed this interview you might like our interview with Stephen Furber, ICL Professor of Computer Engineering University of Manchester Super-human like computer. Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Amazon Podcast, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward! ™ ideaXme Ltd.  

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark interviews Matthew Richardson a Canadian author "Threatened and Recently extinct Vertebrates of the World", primatologist and conservationist. "My forthcoming book, Threatened and Recently-extinct Vertebrates of the World, required me to assess and place some 15,000 species and subspecies within an updated biogeographic framework. I also had to coin common names for more than 5,000 of them; figure out an entirely new system of ecoregions based on elevation to nest within my "realms and regions." find a way to standardize language across the globe in a way that would be mostly acceptable to everyone; and somehow make it interesting for the reader. It is twice the length of "War and Peace." I've gone through three publishers, it took me ten years to write, and I've received zero funding in the process" Matthew Richardson. Ira Pastor comments: He began his professional career as a writer of historical non-fiction, although for the past several years he has mainly worked on academic projects related to wildlife conservation. In 2001 he published "The Royal Book of Lists: An Irreverent Romp Through Royal History from Alfred the Great to Prince William." For much of the next decade he worked as a primatologist and taxonomist for the U.S.-based NGO Conservation International, co-authoring various books and academic papers. Notable among these were Lemurs of Madagascar (book) and the massive primate volume to the Handbook of the Mammals of the World series (for which he also produced all the maps). He also lived and worked, for a time, at the Durrell Wildlife Conservation Trust on the island of Jersey in the Channel Islands, named after British naturalist, zookeeper, conservationist, author, and television presenter, Gerald Durrell. In addition to his writing and editing activities, he has consulted with scientists the world over on questions of conservation and taxonomy, helped to catalog the Royal Ontario Museum's primatology collection, gave lectures, and served as an active member of the International Union for Conservation of Nature (IUCN) Species Survival Commission Primate Specialist Group. He currently has a new book in press entitled “Threatened and Recently-extinct Vertebrates of the World: A Biogeographic Approach” (quote from Matthew above). On this ideaXme episode we will hear from Matthew about: -His background and how he developed a long standing interest in conservation and taxonomy -An introduction to the topic and importance of biogeography studies within conservation -Interesting learnings and trends in his biogeographic studies -The need to reform the IUCN Red List of Threatened Species -The need to focus on wildlife conservation via protecting areas of strategic, biogeographic importance This interview text is in American English. Credits: Ira Pastor interview video, text, and audio. Visit ideaXme: www.radioideaxme.com Contact the founder of ideaXme: andrea@ideaxme.com Follow Ira Pastor on Twitter:@IraSamuelPastor Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public, TuneIn Radio ,I Heart Radio, Google Podcasts, Stitcher, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Michael Levin, Tufts University Professor who holds the Vannevar Bush endowed Chair in the Biology Department, and who serves as both the Director of the Tufts Center for Regenerative and Developmental Biology and Director of the Allen Discovery Center at Tufts. Ira Pastor comments: Form is generally defined as the shape and structure of something as distinguished from the materials that it’s constructed from, and the branch of biology that deals with the form of living organisms, and with the relationships between their structures, is known as morphology. Every level of the human body requires complex form control mechanisms to be functional throughout a lifetime, across the body's many hierarchies (at the levels of DNA, cells, tissues, organs, limbs, and body segments), in order to accomplish a range of biologic outputs from embryogenesis, to growth, repair and regeneration, to preventing everything from tumor formation to transitions into a range of degenerative disease, to even neuro-plasticity in the human brain. Yet, when it comes to topics like shape, size, polarity, position, where the properties and characteristics of the component parts of a system and the reciprocal interplay of all the components on each across these hierarchies are required, researchers need to go well beyond studying an individual gene or protein or stem cell, to a range of fascinating top-down control processes which control complex biological morphology. Today, we have the honor of being joined by a true thought leader of this space, Dr. Michael Levin, Tufts University Professor who holds the Vannevar Bush endowed Chair in the Biology Department, and who serves as both the Director of the Tufts Center for Regenerative and Developmental Biology and Director of the Allen Discovery Center at Tufts. Dr. Levin Researches the Utilization of Bio-electricity for Regeneration: Dr. Levin’s group's focus is on understanding the biophysical mechanisms that implement decision-making during complex pattern regulation and harnessing endogenous bioelectric dynamics toward rational control of growth and form. Dr. Levin's lab current focus: • Understanding how somatic cells form bioelectrical networks for storing and recalling pattern memories that guide morphogenesis. • Creating next-generation AI tools for helping scientists understand top-down control of pattern regulation (a new bioinformatics of shape). • Using these insights to enable new capabilities in regenerative medicine and engineering. Dr. Levin's recent honors include the Scientist of Vision award and the Distinguished Scholar Award. On this episode we will hear from Dr. Levin about: His background and how he became interested in computer science, biology, and the extremely frontier science space of biological morphology control. The introductory concept of a “Morphogenetic Field.” An introduction to the theme of "Developmental Bioelectricity" which refers to the regulation of cell, tissue, and organ-level patterning and behavior as the result of endogenous electrically-mediated signaling. A general theme of the ability of morphogenetic fields and developmental bio-electricity to organize in/out required cells, as well as modify the diseased phenotype, as seen in his experiments in “normalizing” cancer. A general theme of the ability of morphogenetic fields and developmental bioelectricity to accomplish complex regeneration. His views on developmental bioelectricity modulating drugs versus using electroceuticals. His model of "Variational Free-Energy Minimization" as a way for human bodies to store complex pattern information. His work in "non-CNS" information processing, storage, and cognition - such as in aneural organisms which do not possess brains, in non-neural human tissues, and in single cell organisms that agglomerate to form multi-cellular structures, like slime moulds. His experiences in fundraising for frontier sciences, such as with The Paul G. Allen Frontiers Group (the late Microsoft co-founder) whose mission is to "uncover and make visible the emerging frontiers of science, identifying pioneering explorers to create new knowledge, and produce important solutions that make the world better." This interview is in American English Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, be sure to check out our interview with David Mittelstein on Killing Cancer With Ultrasound! Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme Find ideaXme across the internet including on iTunes, YouTube, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Debra Houry, MD, MPH, the Director of the National Center for Injury Prevention and Control (NCIPC) at the U.S. CDC. Ira Pastor comments: On the U.S. Center’s for Disease Control (CDC) "Ten Leading Causes of Death" list, right beneath the two major categories of heart disease and cancer, there is a category called "Unintentional Injuries" which cumulatively took the lives of over 167,000 Americans in 2018. This category consists of a variety of subcategories such as poisoning, traffic accidents, falls, suffocation, drownings, and fire, just to name a few. When one goes to visit a parallel list, the "Ten Leading Causes of Non-Fatal Emergency Department Visits" (a non-fatal injury defined as bodily harm resulting from severe exposure to an external force or substance, including mechanical, thermal, electrical, chemical, or radiant, or a submersion), the numbers go through the proverbial roof, with over 25 million cases reported in the U.S. alone in 2018, with combined direct and indirect costs approaching ¾ Trillion dollars per year. Globally these numbers are equally staggering. Preventing Injury, Violence and Fatalities: Dr. Debra Houry, MD, MPH, is the Director of the National Center for Injury Prevention and Control (NCIPC) at the U.S. CDC. In this role, Dr. Houry leads innovative research and science-based programs to prevent injuries and violence and to reduce their consequences. Prior to joining CDC, Dr. Houry previously served as Vice-Chair and Associate Professor in the Department of Emergency Medicine at Emory University School of Medicine and as Associate Professor in the Departments of Behavioral Science and Health Education and in Environmental Health at the Rollins School of Public Health. Dr. Houry also served as an Attending Physician at Emory University Hospital and Grady Memorial Hospital and as the Director of Emory Center for Injury Control. Her prior research has focused on injury and violence prevention in addition to the interface between emergency medicine and public health, and the utility of preventative health interventions and screening for high-risk health behaviors. Dr. Houry has received several national awards for her work in the field of injury and violence prevention. She was recently elected as a member of the National Academy of Medicine (NAM), received the first Linda Saltzman Memorial Intimate Partner Violence Researcher Award from the Institute on Violence, Abuse, and Trauma, and the Academy of Women in Academic Emergency Medicine’s Researcher Award. She is past president of the Society for Academic Emergency Medicine, the Society for Advancement of Violence and Injury Research, and Emory University Senate. Dr. Houry has served on numerous other boards and committees within the field of injury and violence prevention. Dr. Houry has authored more than 90 peer-reviewed publications and book chapters on injury prevention and violence. Dr. Houry received her MD and MPH degrees from Tulane University and completed her residency training in emergency medicine at Denver Health Medical Center. On this episode we will hear from Dr. Houry about: Her background and how she developed an interest in science, medicine and emergency medicine, and her journey towards her leadership role at U.S. CDC. A general discussion surrounding the "pandemic scale" of injury, both intentional and unintentional, both fatal and non-fatal, and the structures set up at CDC to address these amazing prevalence figures. The CDC's role in combating the opioid epidemic. The CDC's role in combating Unintentional Falls (representing 8+ million of the above-mentioned Nonfatal Emergency Department Visits) and some discussion related to the technological themes of "aging in place" and "smart home care" for the elderly that can help reduce these cases. She will also discuss the CDC's role in combating Sexual Violence and Child Abuse and combating U.S. Gun Violence. This interview is in American English. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, check out our interview about suicide prevention with Dr. Christine Moutier! Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme Find ideaXme across the internet including on iTunes, YouTube, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Matt Kaeberlein, Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences at the University of Washington.  Dr. Matt Kaeberlein's Cross Species Aging Research:  Dr. Matt Kaeberlein, is Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences at the University of Washington. With a PhD from MIT in Biology, and post-doctoral work in the Department of Genome Sciences, University of Washington, his research interests are focused on basic mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. Dr. Kaeberlein has published nearly 200 papers in top scientific journals and has been recognized by several prestigious awards, including a Breakthroughs in Gerontology Award, an Alzheimer’s Association Young Investigator Award, an Ellison Medical Foundation New Scholar in Aging Award, a Murdock Trust Award, a Pioneer in Aging Award, and the Vincent Cristofalo Rising Star in Aging Research. Dr. Kaeberlein's contributions have also been recognized with Fellow status in the American Association for the Advancement of Science, the American Aging Association, and the Gerontological Society of America. Dr. Kaeberlein is a past President of the American Aging Association and has served on their Executive Committee and Board of Directors since 2012. He has also served as a member of the Board of Directors for the Federation of American Societies for Experimental Biology and is currently the Chair of the Biological Sciences Section of the Gerontological Society of America. Dr. Kaeberlein serves on the editorial boards for several journals, including Science and eLife. Dr. Kaeberlein’s scientific discoveries have generated substantial public interest, with featured stories in major media outlets including appearing on the front page of the New York Times, the Today Show, CNN, the UK Telegraph, Popular Science, Time Magazine, Scientific American, NPR, USA Today, National Geographic, and many others. In addition to his primary appointments, Dr. Kaeberlein is the co-Director of the University of Washington Nathan Shock Center of Excellence in the Basic Biology of Aging, the founding Director of the Healthy Aging and Longevity Research Institute at the University of Washington, and founder and co-Director of the Dog Aging Project. On this episode we will hear from Dr. Kaeberlein about: His background and how he developed an interest in genomics, in biology, and in aging. His strategy in studying the "conserved" mechanisms of aging across organisms including yeast, nematodes, mice, and dogs. His studies with the drug Rapamycin in rejuvenating oral health in aging mice. His studies on the purification and analysis of nematode extracellular vesicles and their roles in studying the bio-markers of health and disease. His studies on systems biology in yeast to help illuminate mechanisms of personalized aging. His dog aging studies where he will be studying up to 10,000 dogs, in a 10-year effort aimed at tracking their health and identifying factors that can lengthen their lifespan. This interview is in American English Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, be sure to read this interview with Dr. Mark Wolff! Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme On YouTube: ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews, Naveen Jain, M.B.A, BS, Founder and CEO at Viome as well as founder of several companies including Moon Express, Viome, Bluedot, TalentWise, Intelius and InfoSpace.   Ira Pastor comments: On this ideaXme episode, we are going to head back towards the theme of the human micro-biome, which represents the estimated 100 trillion aggregate of all microbiota (bacteria, fungi, protists, viruses, etc. ) that reside on, within, or symbiogenically as part of the human body, and their downstream effects on human health, wellness, and longevity. Naveen Jain Believes in Using Food as Medicine: Naveen Jain is a philanthropist, technology pioneer and entrepreneur, driven to solve global grand challenges through innovation. He is the founder of several successful companies including Moon Express, Bluedot, TalentWise, Intelius and InfoSpace, and Viome, which is the topic of today's episode. Viome is focused on disrupting healthcare with the goal of “making illness elective”, by identifying microbial bio-markers that are predictive of chronic diseases, and adjusting the microbial imbalance through personalized nutrition, in essence making illness truly a matter of choice, and not a matter of bad luck, using foods as a medicine. Personalized Healthcare: Through Biotech and AI Mr. Jain is also director of the board at the Singularity University where he is focused on educating and inspiring leaders to address humanity’s grand challenges through innovative technologies. Mr. Jain is a director of the board at the XPRIZE Foundation where he is focused on using incentive prizes to find solutions to many of the societal challenges and recently launched a million-dollar Women Safety XPRIZE to empower women around the world. He has been awarded numerous honors for his entrepreneurial successes including, but not limited to, the “Ernst & Young Entrepreneur of the Year”, the “Albert Einstein Technology Medal” for pioneers in technology, the “Ellis Island Medal of Honor”, and the "Most Creative Person” award by Fast Company. In addition to Viome, on the life sciences/biotech front, Mr. Jain is in the process of setting up an incentive prize challenge to develop “Digital Doctor” (AI based expert system) to improve access to primary care physicians around the world. He is also exploring ways to develop a neurometric system to create better learners and to develop neuroscience based multi-sensory video games that are effective and additive to teach students skills like math, science and history. Mr. Jain is also a strong believer that we should be doing a lot more on the synthetic biology front, creating living bio-factories to reduce global shortages of food, and use microbes to help with cleaning water and generating energy from plentiful resources like ocean water. On this ideaXme episode, we will hear from Mr. Jain about: His background, how he developed an interest in engineering, and about his info-tech business success in the "pre-Viome" era. Why he made the jump into the risky biotech industry. Viome's business model, products, and services. Viome's collaboration with the Mayo Clinic on AI-driven personalized nutritional strategies to help understand sleep and obesity. Viome's collaboration with GlaxoSmithKline (GSK) to develop vaccine-based therapies to help prevent and treat chronic diseases. The state of the biotechnology financing world. His Moon Express initiatives. This interview is in American English Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, read our interview with Dr. Michael Lustgarten! Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews, Dr. Marcus Remmers, PhD, Chief Technology Officer at DSM. Ira Pastor comments: As we continue upon our core themes of health, wellness, and longevity, amongst the unique aging demographic shifts occurring in the coming decades, we can’t overlook the importance of the global chemicals industry in coming up with novel solutions for the world's population. Central to the modern world economy, the global chemicals industry comprises a $4 trillion industry which converts a variety of raw materials into more than 70,000 different products. Holistic Health Life sciences chemicals (about 30% of the dollar output of the chemistry business) include a wide variety of differentiated chemical and biological substances, pharmaceuticals, diagnostics, animal health products, vitamins, and agricultural products. Speciality chemicals, representing another 10%, are a broad range of higher value materials used on the basis of their performance or function, and may include, but are not limited to such classes as adhesives, colors, fragrances, industrial gases, lubricants, paints, polymers, and surfactants. Royal DSM, commonly known as DSM, is a Dutch multinational active in the fields Nutrition, Health and Sustainable Living. Headquartered in the Netherlands, DSM employs over 21,000 people, in approximately 50 countries, and has annual sales of around €9 billion. Dr. Marcus Remmers: We’re honored today to be joined by Dr. Marcus Remmers, Chief Technology Officer at DSM, who is responsible for DSM’s global Science and Technology portfolio. Dr. Remmers graduated in Chemistry at the Universities of Münster and Freiburg, completed his Doctorate Thesis at the Max-Planck-Institute for Polymer Chemistry in Mainz, and did post graduate research at Stanford, Caltech and Cambridge. Dr. Remmers has strong knowledge and experience in polymer and life sciences R&D, business operations, business development, strategy and change management. Dr. Remmers started his career with Hoechst/Intervet in several managerial roles. In 2001, he joined Merial Ltd. (the animal health division of Merck, and then Sanofi), where he had roles in Business Development, Country Management, Project and Portfolio Management and R&D in Pharma and Biologics. In April 2017, Dr. Remmers became Chief Technology Officer of DSM, where he works to secure the company’s technology position and at the same time execute on a mission for "purpose-led innovation", developing disruptive business models for not just profits, but for sustainability, where future leaders will need purpose in their hearts, not just their heads, as they develop the next generation of products for humanity. On this show we will hear from Dr. Remmers about: His background, how he became interested in science, in chemistry, and ultimately how he worked his way into the leadership roles of some of the world's largest chemical and pharma companies. His experience/learnings/contrasts between the pharmaceuticals business and the chemicals business. The importance of AI/data management in the development of new chemical products and holistic nutrition such as in the case of DSM’s "personalized nutrition platform". The topic of “Aging in Place” from a chemicals industry perspective and how the development of materials that are lighter, stronger and more durable, can enhance the ability of the elderly to live in their own homes and communities safely, independently, and comfortably. About the role of sustainability in a purpose-led, innovation focused organization. This interview is in American English. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, read our interview with the CEO of BlueNalu, who use biotech to create sustainable food resources. Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify, www.radioideaxme.com and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Andrei Gudkov, PhD, DSci, pre-eminent cancer researcher who serves as Senior Vice President, Research Technology and Innovation, Chair of the Department of Cell Stress Biology, and a member of the senior leadership team for National Cancer Institute (NCI) Cancer Center Support Grant at Roswell Park Comprehensive Cancer Center. Ira Pastor comments: As we continue on our path through the topics of the diseases of aging and healthy longevity, we are going to take a fascinating journey upstream from many of the hallmarks and forms of damage found in aging tissues, to one of the very interesting drivers of aging processes, namely the RetroElement space (termed the "retrobiome" by our guest). The retrobiome comprises a considerable fraction of eukaryotic genome, which for a long time was overlooked as "junk DNA", but in recent years is now realized to have important influence on genome functioning, and where inappropriate activation can serve as an internal clock mechanism determining aging and chronic disease progression. Dr. Andrei Gudkov: Dr. Andrei Gudkov, PhD, DSci, is a pre-eminent cancer researcher who serves as Senior Vice President, Research Technology and Innovation, Chair of the Department of Cell Stress Biology, and a member of the senior leadership team for National Cancer Institute (NCI) Cancer Center Support Grant at Roswell Park Comprehensive Cancer Center. Dr. Gudkov is responsible for building on the basic and translational research strengths of the Cell Stress Biology program in DNA damage and repair, photodynamic therapy, thermal and hypoxic stress and immune modulation. Dr. Gudkov assists the President and CEO at Roswell Park in developing and implementing strategic plans for new scientific programs and to enhance collaborations in research programs with regional and national academic centers as well as with industry. Increasing Lifespan in Humans and Dogs: Before joining Roswell Park, Dr. Gudkov served as chair of the Department of Molecular Genetics at Lerner Research Institute, Cleveland Clinic Foundation, and Professor of biochemistry at Case Western University. He earned his doctoral degree in Experimental Oncology at the Cancer Research Center, USSR and a Doctorate of Science (D.Sci) in Molecular Biology at the Moscow State University, USSR. He has authored or co-authored 135 scientific articles and holds 27 patents. Dr. Gudkov is also a serial entrepreneur who founded Cleveland BioLabs, Inc., OncoTartis LLC and Everon Biosciences, Inc. He holds the position of Director & Chief Scientific Advisor at Panacela Labs, Inc., Chief Scientific Officer of OncoTartis LLC, Chief Scientific Officer for Everon Biosciences, Inc., Chief Science Officer at Genome Protection, Inc. and Chief Scientific Officer of Cleveland BioLabs, Inc. Andrei V. Gudkov is also on the board of Incuron LLC. Dr. Gudkov is also on the Scientific Advisory Board and author of founding concept for the Vaika program, which is a not-for-profit charitable medical research organization with a mission to extend the healthspan and lifespan of domestic animals, via a novel clinical study using aged sled dogs. On this ideaXme episode we will hear from Dr. Gudkov about: His background and how he developed an interest in oncology, in molecular biology, in aging, and the study of the retrobiome. A history of retrobiome research in the scientific community. The concept of treating aging by counteracting intrinsic DNA damage and immunosenescence and retrobiome vaccination. His oncology/cancer research program. About the Vaika program - a clinical study in aged sled dogs in order to test whether inhibition of retrobiome will be beneficial for dogs’ healthspan and longevity. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, be sure to read this interview Exploring the Human-Animal Connection for Health and Wellness! Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme On YouTube: ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Christine Moutier, MD, Chief Medical Officer, at the American Foundation for Suicide Prevention (AFSP). Ira Pastor comments: According to the World Health Organization (WHO), close to 800,000 people die due to suicide every year, which is one person every 40 seconds. Suicide is a global phenomenon and occurs throughout the lifespan, and there are indications that for each adult who died by suicide, there may have been more than 20 others attempting suicide. According to the U.S. Centers for Disease Control and Prevention (CDC) "Leading Causes of Death Report", in 2017 suicide was the tenth leading cause of death overall in the United States, claiming the lives of over 47,000 people; Suicide was the second leading cause of death among individuals between the ages of 10 and 34, and the fourth leading cause of death among individuals between the ages of 35 and 54. There were more than twice as many suicides in the United States as there were homicides. Aiding Suicide Prevention Through Psychiatry Dr. Christine Moutier, MD is the Chief Medical Officer at the American Foundation for Suicide Prevention. Dr. Moutier earned her medical degree and training in psychiatry at the University of California, San Diego, and has been a practicing psychiatrist, professor and dean in the UCSD School of Medicine, medical director of the Inpatient Psychiatric Unit at the VA Medical Center in La Jolla, and has been clinically active with diverse patient populations, such as veterans, Asian refugee populations, as well as physicians and leaders with mental health conditions. She also served as co-investigator for the Sequenced Treatment Alternatives to Relieve Depression study (STAR*D), a large National Institute of Mental Health (NIMH) trial on the treatment of refractory depression. Dr. Christine Moutier’s Career in Psychiatry  Dr. Moutier has authored numerous articles and book chapters for publications such as the Journal of the American Medical Association, Academic Medicine, the American Journal of Psychiatry, the Journal of Clinical Psychiatry, Psychiatric Times, Depression and Anxiety, and Academic Psychiatry. She has testified before the U.S. Congress and spoken at the White House, she was the host of AFSP’s documentary on surviving suicide loss, The Journey, and has appeared as an expert in The New York Times, The Washington Post, Time magazine, The Economist, The Atlantic, the BBC, NBC, CNN and other print and television outlets. She is also a member of the National Academy of Medicine (NAM) Action Collaborative on Clinician Well-Being and Resilience. On this episode we will hear from Dr. Moutier about: Her background and how she got interested in medicine, in psychiatry, and became a thought leader in the area of suicide prevention. The American Foundation for Suicide Prevention (AFSP). The top 10 learnings of why so many people are dying by suicide in 2020. The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) collaborative study on the treatment of recalcitrant depression, a leading driver of suicide. Suicide connections to modern stressors/traumas such as the Coronavirus pandemic. Nutritional interventions to help prevent depression related suicide. The National Academy of Medicine's Action Collaborative on Clinician Well-Being and Resilience and the understandings of challenges related to clinician well-being, stress and burnout, and suicide. This interview is in American English Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, be sure to check out our interview with Dr. Ekaterina Malievskaia! Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme On YouTube: ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Lou Cooperhouse, President and CEO of BlueNalu. Ira Pastor comments: Global demand for seafood is at an all time high, as consumers are increasingly choosing to eat an extraordinary variety of seafood products that exist worldwide. Unfortunately, our global supply for seafood cannot keep pace with this demand, as populations of marine species have halved since 1970. This is due to overfishing, illegal fishing, rising ocean temperatures, acidification, the effects of trawling, and a number of other environmental, social, and political challenges. At the same time, consumers are looking for more from their food choices. Consumers are increasingly concerned about animal welfare and the conditions in which fish are farmed and caught. In addition, they are increasingly concerned about their own personal welfare, as seafood can be a source of mercury, toxins and poisons, pathogens, viruses, and parasites, micro-particles of plastics due to plastic pollution in our ocean, and a variety of other environmental pollutants. Using Biotechnology to Create a Sustainable Cell Based Seafood Food Resource Cellular agriculture (or aquaculture per our theme today) focuses on the production of products from cell cultures using a combination of biotechnology, tissue engineering, molecular biology, and synthetic biology to create and design new methods of producing proteins, fats, and tissues that would otherwise come from traditional agriculture or aquaculture. Lou Cooperhouse, is President and CEO of BlueNalu, a company whose mission is to be the global leader in cellular aquaculture, providing consumers with great tasting, healthy, safe and trusted cell-based seafood products that support the sustainability and diversity of our ocean. Lou Cooperhouse With degrees in Food Science and Microbiology, both from Rutgers University, Mr. Cooperhouse is recognized as a leading global authority in food business innovation and technology commercialization, with extensive leadership experiences throughout his 35-year career in the food industry. Most recently, Mr. Cooperhouse served as CEO of Food Spectrum, LLC, where he provided a broad array of strategic consulting and business management expertise to the food industry, as well as a founder and the Executive Director of the Rutgers University Food Innovation Center (FIC), and led this program for approximately 15 years. Previously, Mr. Cooperhouse served as President & COO of F&S Produce, a leading regional supplier of fresh-cut produce and value-added refrigerated foods, and Co-Founder, President and CEO of MenuDirect Corporation, a unique health, wellness, and nutrition company, which provided meal solutions for individuals with celiac disease, diabetes, PKU and dysphagia. Earlier in his career, Mr. Cooperhouse held positions of increasing responsibility at Campbell’s Soup, ConAgra, Nestlé-funded Culinary Brands, Idle Wild Farms, and Grand Union Supermarkets in areas of business development, product development, quality assurance, and operations. In addition, Mr. Cooperhouse has considerable expertise in food safety and quality assurance systems, and has provided leadership at numerous FDA and USDA-inspected operations, and has conducted third-party audits of dozens of food companies throughout the nation. He is Certified in Preventive Controls for Human Food (issued by the Food Safety Preventive Controls Alliance), is a Certified Trainer in Hazard analysis and critical control points (issued by the International HACCP Alliance), and is also Certified as a ServSafe Food Protection Manager (issued by the American National Standards Institute). On this episode we will hear from Mr. Cooperhouse: About his background in the food science, safety and technology space. About the BlueNalu company. About the processes involved in creating lab grown fish meats. About the types of fish meats they are planning on commercializing first. About any technology hurdles on the route to market. About regulations surrounding cell based aquaculture and about any "Exotic" marine food requests from customers. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, be sure to read our interview with Dr. Hamed Faridi, Chief Science Officer of McCormick. Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme On YouTube: ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Cheryl D. Hicks, Executive Director and CEO at Toilet Board Coalition. Ira Pastor comments: So on the last several shows, as we have spent time on the themes of health, wellness, and aging, we’ve been speaking to a broad range of experts primarily in the fields of therapeutic and preventative interventions as it pertains to the chronic degenerative diseases in the developed world. And I always find it interesting when you go to conferences nowadays focused on the topics of wellness, longevity or healthspan, somebody will always give a presentation highlighting how improvements in sanitation technically did as much, if not more, for humanity and human lifespan (doubling it), than modern medicine has done over the last century. And that’s why I find it so amazing that in 2020, an estimated 2.4 billion people around the globe, still lack access to the basic tools of improved sanitation (toilets and latrines) That represents 35% of the world’s population! The Global Sanitation Crisis: One billion people on this planet still have to defecate in the open and at least 10% of the world’s population is thought to consume food irrigated by raw wastewater. An estimated 800,000 children, younger than 5 years of age, perish each year from diarrhea, cholera, dysentery, hepatitis A, typhoid and polio. The Toilet Board Coalition (TBC) is a business-led partnership and platform, which has the ambition to address the global sanitation crisis by accelerating the Sanitation Economy, a brand new marketplace for innovation, entrepreneurship and investment, to transform sanitation systems from an unaffordable public cost, to an untapped business opportunity, and deliver significant impact to business and society. TBC enables private sector engagement, connecting large and small companies, and ensuring close collaboration between private, public and non-profit sectors with the common goal to achieve United Nations (UN) Sustainable Development Goal 6 (SDG6), which is "universal access to sanitation." Partners in the TBC include such entities as Unilever, KimberlyClark, Firmenich, Veolia, Tata, USAID, the World Bank and Unicef. The Toilet Board Coalition also runs the Toilet Accelerator, the world’s first accelerator program dedicated to sanitation entrepreneurs in low-income markets. Cheryl D. Hicks: Cheryl Hicks, Toilet Board Coalition Executive Director and CEO, is an experienced business, investment and sustainable development professional. Cheryl brings over 20 years of experience developing innovative approaches to responsible business strategies, impact investment strategies, and high performing multi-stakeholder collaborations. Before joining the TBC, Cheryl was the Sustainability Investment Partner and Head of Impact at Quadia Impact Finance in Geneva. Throughout her career, Cheryl has held several positions with sustainable development platforms, and worked with fortune 500 global companies, investors and start-ups across sectors such as healthcare, consumer goods, food, forestry, chemistry, and renewable energy. Cheryl began her career in corporate sustainability with the World Business Council for Sustainable Development (WBCSD) in Geneva, Switzerland. On this ideaXme episode we will hear from Cheryl: About her background in the investment industry, and how she got interested in doing something about this major problem known as "the sanitation crisis.” About the background of the Toilet Board Coalition. About the dynamics of the circular, closed loop visions of TBC for the Sanitation Economy. About the Sanitation Economy Accelerator and technologies they invest in. About toilet technologies in space and the TBC collaboration with the European Space Agency Business Applications Group. This interview is in American English Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter: @IraSamuelPastor If you liked this interview, be sure to check out our interview with Ambassador Juan José Gómez Camacho, Mexico’s current Ambassador to Canada! Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme On YouTube: ideaxme Find ideaXme across the internet including on iTunes, SoundCloud, Radio Public, TuneIn Radio, I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Derek Yach, founder, president, and board member of The Foundation for a Smoke-Free World, and passionate advocate for health promotion and disease prevention. Dr Yach's objective is to end smoking in this generation. We investigated to see how that might be achieved. Ira Pastor Comments: The World Health Organization (WHO) estimates that we currently have over 1.1 billion smokers on earth, and that tobacco kills more than 8 million people each year. More than 7 million of those deaths are the result of direct tobacco use while around 1.2 million are the result of non-smokers being exposed to second-hand smoke. The U.S. Centers for Disease Control (CDC) say that cigarette smoking is responsible for more than 480,000 deaths per year in the United States, including more than 41,000 deaths resulting from secondhand smoke exposure. This is about one in five deaths annually, or 1,300 deaths every day. Smoking leads to disease and disability and harms nearly every organ of the body. More than 16 million Americans are living with a disease caused by smoking including cancer, heart disease, stroke, lung diseases, diabetes, and chronic obstructive pulmonary disease (COPD), which includes emphysema and chronic bronchitis, as well as increasing risk for tuberculosis, certain eye diseases, auto- immune disorders including rheumatoid arthritis, and erectile dysfunction in males. Total economic cost of smoking in the U.S. alone is more than $300 billion a year, including nearly $170 billion in direct medical care for adults and more than $156 billion in lost productivity due to premature death and exposure to secondhand smoke. Ending Smoking for Good The Foundation for a Smoke-Free World (FSFW) is an independent, nonprofit organization that funds research, promotes innovation, and supports collaborative initiatives committed to reducing deaths and diseases caused by smoking, and ending smoking in this generation. They strive to identify and address the unique needs of the developing world as they relate to tobacco cessation and harm reduction, and serve as a convener of global research supporting the reduction of tobacco use, while helping to address the impact of decreased smoking rates on agriculture and economies. The Foundation’s work focuses on three core areas: Health, Science, and Technology (HST); Agriculture and Livelihoods; and Industry Transformation. Dr. Derek Yach Has Forged a Career Around Anti-Smoking Advocacy Dr. Derek Yach has been a global health expert and anti-smoking advocate for more than 30 years, and is also a passionate advocate for health promotion and disease prevention. Dr. Yach is a former World Health Organization (WHO) cabinet director and executive director for noncommunicable diseases and mental health where he was deeply involved with the development of the world’s treaty on tobacco control, the Framework Convention on Tobacco Control (FCTC). He is also the former chief health officer of the Vitality Group, executive director of the Vitality Institute, Senior Vice President, global health and agriculture policy at PepsiCo, director of global health at the Rockefeller Foundation, and a professor of global health at Yale University. He has authored or co-authored more than 250 peer-reviewed articles on global health and has served on several advisory boards, including the World Economic Forum, Cornerstone Capital, and the Wellcome Trust. Dr. Yach is a dual citizen of the United States and South Africa. He has an honorary DSc from Georgetown University, Bachelor of Medicine and Surgery from the University of Cape Town, BSc (Epidemiology), University of Stellenbosch, and an MPH from the Johns Hopkins Bloomberg School of Public Health. Disclosure: The Foundation for a Smoke-Free World has received its initial funding pledge of $80 million USD annually for 12 years, beginning in 2018 from Philip Morris International (PMI) - The Foundation has a nonprofit status as a US 501c3 organization, and by law and policy must operate completely independently from PMI, and cannot engage in activities designed to support PMI’s interests. Further, PMI can have no involvement or say in their work. On this episode we will talk to Dr. Yach about: His Background and how he developed an interest in medicine, public health, and smoking cessation. The Philip Morris International's funding of FSFW. About FSFWs Global State of Smoking Poll, Health, Science, and Technology programs, Agricultural Transformation Initiative and Industry Transformation efforts. Finally, we’ll hear about Dr. Yach's views on the dangers/health issues related to marijuana smoking. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Hamed Faridi, Chief Science Officer of McCormick. Ira Pastor comments: Many scientists believe that we have only touched the surface with what the botanical world, and its unique ways to naturally manufacture complex, phyto-chemical cocktails, with novel bio-activities, has to teach us. Additionally, while we all may keep our pharmaceuticals, and dietary supplements, and related health products, tucked away within our medicine cabinets, we tend to forget about that other cabinet of health that we all have in our homes, which is a treasure trove of phyto-medicinal possibilities - the spice cabinet. Dr. Hamed Faridi is the Chief Science Officer Emeritus, McCormick & Company, the world's largest spice company (HQ - Maryland USA), a Fortune 1000 company, with 11,700 employees, which manufactures, markets, and distributes spices, seasoning mixes, condiments, and other flavoring products for the industrial, restaurant, institutional, and home markets. A renowned food industry leader, Dr. Faridi has led a global team of 500+ scientists responsible for thought leadership, scientific research, product development, health & wellness, and sustainability to support the global businesses of McCormick. Dr. Faridi has been referred to as the “voice of science” for McCormick & Company and advises the company’s CEO, and senior executives on strategic corporate initiatives such as technology investment and potential M&As and serves on several business councils. Under his leadership, McCormick’s R&D program has been transformed and is rated by investors and global customers as one of the most innovative in the industry. His science-based approach to “Flavorful Healthy Eating” is recognized as a groundbreaking platform for improving public health. His vision led to the formation of the McCormick Science Institute (MSI) as a research-driven organization to advance scientific understanding of the potential health benefits of culinary spices and herbs. This research prompted a close partnership with US Departments of Agriculture (USDA), Health and Human Services (HHS) and the White House, to help in the implementation of the 2015-2020 Dietary Guidelines for Americans. In 2013, in partnership with IBM, he initiated the creation of an Artificial Intelligence (AI) platform for food and flavor product development with the potential to change the course of the industry and enhance the universal eating experience of consumers around the world, by tapping in on over 40 years of sensory, culinary, chemistry and scientific data collected by McCormick R&D scientists in 14 countries. He has published six books and dozens of scientific articles in food science and technology, and has been a guest lecturer at conferences and research institutions in 22 countries. He has also served on several boards of professional and trade associations in the U.S. and Europe. He was elected and served as president of the American Association of Cereal Chemists (AACCI) and the Flavor & Extract Manufacturers Association (FEMA). In addition, he has served on Advisory Councils of food science departments for four major universities. He is the recipient of numerous awards and was honored as a Fellow by the Institute of Food Technologists (IFT) and the AACCI. Dr. Faridi is on the Board of Trustees at Maryland University of Integrative Health (MUIH) in Laurel, MD, and has served on the Board of Directors of the St. Joseph Medical Center in Towson, Maryland. Prior to joining McCormick & Company, Dr. Faridi served on the faculty of Washington State University and held R&D executive positions at Nabisco Food Group where he received several awards for innovation and business impact. Dr. Faridi received his MS and Ph.D both in food science from Kansas State University, and an MBA from Fairleigh Dickinson University. On this show we will hear from Dr. Faridi: About his background and how he developed an interest in food, science, herbs, and medicinal plants, and rose to a position of leadership in McCormick. About the importance of the study of the combinatorial phytochemical mixtures found in culinary herbs and spices and his work in AI to come up with novel flavor combinations. He’ll discuss the anti-microbial potential of culinary herbs and spices and sustainability practices in the herb and spice industry. Finally, we’ll hear about the use of flavor science to impact eating behavior, obesity, and other metabolic disorders. Credits: Ira Pastor interview If you liked this interview, be sure to check out our interview with Dr. Ellen de Brabander about the future of food! Follow ideaXme on Twitter: @ideaxm On Instagram: @ideaxme Find ideaXme across the internet. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Egy nulla nulla. Mindenféle rovatok, hírek és emberek a múltból és a jövőből. Jegyzetek Kedvenc híreink az elmúlt 4 évből rovat Scully: “there's still hop to save the planet! (https://www.technologynetworks.com/genomics/news/the-future-of-hoppy-beer-298806)” Dávid: Watson főz (https://nlc.hu/gasztro/20160428/watson-ibm-szakacs-robot-mesterseges-intelligencia-havas-dora-kognitiv/) Űrdorombolás (https://index.hu/tudomany/til/2016/11/08/miert_dorombol_a_macska/) Harci lámák (https://444.hu/2017/07/09/robotokra-cserelte-a-harcteri-lamait-az-izraeli-hadsereg) Escobar tesójának mobilja (https://www.prnewswire.com/news-releases/pablo-escobars-brother-releases-349-foldable-smartphone-300966449.html) Generált mindenféle (https://aiweirdness.com) Damage: Vantablack a Coachellán (https://www.theverge.com/2019/4/24/18512555/gesaffelstein-coachella-performance-vantablack-monolith) LAZERBAZOOKA (https://www.youtube.com/watch?v=IzUoe-9bKa0&feature=youtu.be) Kávészállító drón (https://pdfpiw.uspto.gov/.piw?PageNum=0&docid=10040551) BioQuark feltámadás (https://www.statnews.com/2017/06/01/brain-death-trial-stem-cells/) MEGABOT vs KURATAS (https://newatlas.com/giant-robot-fight-results/51804/) Balázs: Izraeli kibersrácok a Whatsappon (https://www.ft.com/content/4da1117e-756c-11e9-be7d-6d846537acab) és a Ben Gurion egyetemen (https://cyber.bgu.ac.il/advanced-cyber/airgap) Universal Paperclips (http://www.decisionproblem.com/paperclips/) Reméljük, a következő 100 adásban egyszer sem kell ezzel foglalkoznunk rovat Adam Savage riksa + Spot (https://www.youtube.com/watch?v=zyaocKS3sfg) Tudatos elektronok (https://futurism.com/professor-claims-electrons-quarks-experience-consciousness) PewDiePie-nek válaszolnak a viszkis arcok (https://www.youtube.com/watch?v=xsOfoS8vfU4) Kedvenc híreink a következő 4 évből rovat Ruhahajtogatás (https://www.youtube.com/watch?v=b5AWQ5aBjgE) 4. generációs nukleáris reaktoros hír 2011-ből (https://www.origo.hu/idojaras/20110117-negyedik-generacios-atomeromu-gyorsreaktor-vilagelso-kiserleti-atomeromu-epulhet-magyarorszagon.html) Kézikönyv a 4. Generációs atomreaktorokhoz (https://books.google.hu/books?id=8JLBCQAAQBAJ&pg=PA257&lpg=PA257&dq=esnii+reactor+hungary&source=bl&ots=ZWzpgoFfdT&sig=ACfU3U1mua5dOxiMdHc0pcCUnrsxbRKm0w&hl=en&sa=X&ved=2ahUKEwiYka28qNnnAhWtAxAIHQSOD8UQ6AEwAnoECBgQAQ#v=onepage&q=esnii%20reactor%20hungary&f=false) Álomvendég a 200. adásra rovat Samantha Cristoforetti (https://en.wikipedia.org/wiki/Samantha_Cristoforetti) Nick Bostrom (https://en.wikipedia.org/wiki/Nick_Bostrom) Damage zenél: itt. (https://planetdamage.bandcamp.com) és itt is (http://www.planetdamage.com/music)

Ira Pastor, ideaXme exponential health ambassador, interviews Fred Frank, Founder and Chair of Evolution Life Science Partners, an investment bank focused on the needs of life sciences and healthcare companies. Ira Pastor Comments: On several recent shows we’ve been discussing some of the novel, alternative funding pools that have been emerging in and around the biotech space, specifically related to some of the unmet medical needs of which we have been focusing on, on the ideaXme show, particularly related to the age-tech and longevity biotech fronts. We have had guests join us from both the $125 Million Healthy Ageing Challenge program of UKRI (UK Research and Innovation)and the US$30 Million Healthy Longevity Global Grand Challenge of the U.S. National Academy of Medicine. We’ve have also talked to folks at the XPrize Foundation, specifically related to their upcoming inducement prize contest for therapeutics for the diseases of aging. However, today we are going to get back to back to basics; "Back to the street" as they say, to Wall Street, where the majority of the big action and big deals occur. Fred Frank I’m honored to be joined this morning by Mr. Fred Frank. Mr. Frank is an investment banker, and with more than 50 years of experience on Wall Street, is widely considered to be one of the first investment bankers to have ever specialized in the areas of biotechnology, pharmaceuticals, and health care services. Routinely listed as one of the top contributors to the world biotechnology, Mr. Frank has served in a variety of roles over the years including, but not limited to, Vice Chairman at Lehman Brothers, Barclays Capital, and the Peter J. Solomon Company. He is credited as lead underwriter for over 125 IPOs, and as a negotiator in over 75 mergers and acquisitions, including the mega Bristol-Myers Squibb merger, and the Hoffmann-La Roche acquisition of Genentech. He was around doing deals when companies like Genentech and Cetus (which eventually became Chiron) were tiny startups, so has really seen the evolution of this business from the very beginning. Mr. Frank's Work Mr. Frank is currently the founder and chair of Evolution Life Science Partners, an investment bank focused on the needs of life sciences and healthcare companies, including capital raising, licensing/partnering, and M&A, and it's partners have executing hundreds of deals with an aggregate value in excess of $125 Billion. Along with his wife Ms. Mary Tanner, another major bio/health investment banking force on Wall Street, Mr. Frank is Trustee of the Tanner Frank Foundation of New York Citywhich is involved in variety of charitable giving activities. Mr. Frank has won numerous awards over the years including The Richard J. Bolte Sr. Award which recognizes "outstanding contributions by a leader who provides products or services vital to the continuing growth and development of the chemical and molecular sciences community", the Albert Einstein Award from the Weizmann Institute of Science, and the Top 100 living contributors to biotechnology by the Reed Elsevier organization. On this show we will hear from Mr. Frank About his background, how he became interested in investment banking, in biotech/healthcare M&A deals, the early days of recombinant DNA technology development and his realisation of what a game-changing opportunity it was for the industry in the 1970s. His views on the current big pharma / biotech M&A balance dynamics in 2020. His views on the "Unicorn" biotech phenomena, a term used in the venture capital industry to describe privately held startup companies with a value of over $1 billion. Finally, we'll hear his views on the current state of the biotech venture capital industry, as well as the longevity / anti-aging biotech segment. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter:@IraSamuelPastor If you liked this interview, be sure to check out ourinterview with Dr. Roey Tzezana, lead researcher at XPRIZE! Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including oniTunes,SoundCloud,Radio Public,TuneIn Radio,I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr. Victor Dzau, President of the United States National Academy of Medicine (NAM)and of the United States National Academy of Sciences (NAS). Ira Pastor Comments: On today's show we are going to continue upon a theme that we started a few weeks ago, and that is in today's (and the near future's) world, we are facing this major demographic shift: by 2050, the estimated population of those 65+ will represent 18% of the global population, with an estimated group of 500 million octogenarians and above. How do we continue to foster innovations to deal with this population aging that is, needless to say, poised to impose a significant strain on economies, health systems, and social structures worldwide? In this world with amazing pockets of wealth, how do we make sure some of it (outside of traditional life science venture capital, PE model) begins to get appropriately channeled to support the next generation of breakthroughs in "healthy longevity," so that all of us can benefit from the tremendous opportunities it has to offer? Dr. Victor Dzau Our guest today is truly a "though leaders thought leader" on the topic and really needs no introduction for those that spend time in the biomedical space. Dr. Victor Dzau is the President of the United States National Academy of Medicine (NAM), of the United States National Academy of Sciences (NAS)and most recently, prior to that, previously served as president and CEO of Duke University Medical Center. A leading cardiovascular scholar, Dr. Dzau was the Hersey Professor of the Theory and Practice of Medicine at Harvard Medical School and served as Chairman of the Department of Medicine at Harvard Medical School's Brigham and Women's Hospital, as well as Chairman of the Department of Medicine at Stanford University. He was the previous Chairman of the National Institutes of Health (NIH) Cardiovascular Disease Advisory Committee, and he served on the Advisory Committee to the Director of NIH. Dr. Dzau has made a significant impact on medicine through seminal research in cardiovascular medicine and genetics, his pioneering work in the discipline of vascular medicine, and his leadership in health care innovation. His seminal research laid the foundation for the development of angiotensin-converting-enzyme (ACE) inhibitors, which are used globally for the treatment of high blood pressure and congestive heart failure. He pioneered gene therapy for vascular disease, being the first to introduce DNA decoy molecules to block transcriptions as gene therapy in humans. Under his leadership at NAM, Dr. Dzau organized and implemented the Global Roadmap for Healthy Longevity,an international commission that will assess available evidence and recommend strategies for global societies to maintain the health and productivity of aging populations, as well as The Healthy Longevity Global Competition, which is a $30 million program that endeavors to "kick start" innovation to support healthy longevity through a series of monetary awards and prizes. On this show we will hear from Dr. Dzau: About his background, how he developed an interest in medicine, cardiology, and how he has ultimately arrived at the epicentre of the "healthy longevity" space in 2020. In a world where annually a tremendous amount of capital gets poured into bio-medical R&D, why such competition / challenge / prize models in so crucial in "un-met" areas like healthy longevity research. The history of the Healthy Longevity Grant Challenge, the challenges in bringing together such a wide range of stakeholders / investors, and how the process will work. About specific areas of healthy longevity R&D that you he is personally most excited about. His visions for the "internationalisation" of the healthy longevity challenge model and how he see it further spreading around the globe and in size. His role on the International Commission on Clinical Use of Heritable Human Genome Editing. About NAMs Action Collaborative on Clinician Well-Being and Resilience. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter:@IraSamuelPastor If you liked this interview, be sure to check out our interview with Mr. George MacGinnis, Challenge Director of the Healthy Ageing Programme at UK Research and Innovation. Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including oniTunes,SoundCloud,Radio Public,TuneIn Radio,I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Sanga Kanthema, 24 year old electronics specialist and founder and CEO of two Malawi-based companies, Dolphin Health Innovations and QubiX Robotics. Ira Pastor Comments: On today’s show we are going to continue our “virtual global road trip” and our discussions about STEM (Science, Technology, Engineering and Mathematics) initiatives, and about ways they are disrupting the status quo. In doing so, we are heading back to the continent of Africa. But first, we are going to start with some disconcerting statistics on the healthcare front. It estimated that there are only 25 consultant oncologists to service all 160 million Nigerians; only 1 pathologist per 700,000 Sudanese; only 1 pathologist per 1.5 million Ugandans; Nigeria only has 288 doctors for 14 million people; and Mozambique only has 548 doctors for 26 million people. Needless to say, mobile health technologies (smart phones, telemedicine, medical drones, etc.) all offer the potential for disruptive solutions, especially in conditions when instead of relying on traditional infrastructure and healthcare models, populations need access to inexpensive, easily accessible, problem solving technologies, especially when the nearest doctor is a couple hundred miles away. Malawi The republic of Malawi is a landlocked country in Southeastern Africa, bordered by Zambia to the northwest, Tanzania to the northeast, and Mozambique on the east, south and west, and has an estimated population of around 18 million people. Of the world’s lesser developed countries, the government faces many challenges in terms of lower life expectancies, high infant mortality, a high prevalence of HIV/AIDS, and the World Health Organization (WHO) recently ranked it’s healthcare system at 185 out of 191 countries rated. However, with all of those challenges, we still see the emergence of young thought leaders and entrepreneurs who are looking to change the status quo utilizing STEM thinking, business innovation, and the tools that are available to them. Sanga Kanthema: Sanga Marcarios Kanthema a 24 year old electronics specialist, and founder and CEO of two Malawi-based companies, Dolphin Health Innovations Inc.,a digital health startup developing on-line ECG and stethoscope technologies, and well as QubiX Robotics Inc.,which is developing bionic prosthetics, all from inexpensive, discarded electronics devices. He is also the Malawi Ambassador for TME Education, an international program that looks to popularise electronics and technology-related knowledge around the world, especially in regions where access to proper training is quite limited. On this episode we hear from Mr. Kanthema: About his background, how he developed an interest in electronics, STEM, biomedical device development, and entrepreneurship. The current state of affairs related to technology education and development in Malawi. His work at Dolphin Health Innovations and QubiX Robotics. Finally, about his Malawian tech ambassadorship for TME Education. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter:@IraSamuelPastor If you liked this interview, be sure to check out ourinterview with Ósìnàkáchì Ákùmà Kálù on technological development in Africa! Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including oniTunes,SoundCloud,YouTube, Radio Public,TuneIn Radio,I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr. Renard Siew, Climate Change Advisor with the Centre for Governance and Political Studies in Kuala Lumpur. Today we are going to be talking about Sustainability and Climate Change; two topics that have really come to the public forefront in recent months, and which directly impact all of our respective health and longevity. Dr. Renard Siew Our guest today is Dr. Renard Siew. Dr. Siew has PhDs in both Civil and Environmental Engineering (Cambridge University) and Management, Technology and Economics (ETH Zürich PhD). Dr. Renard Siew is a Climate Change Advisor with the Centre for Governance and Political Studies in Kuala Lumpur which is an interdisciplinary research center, bridging the fields of economics, political science, sociology, business and law, which focuses on the problems and challenges raised by the current political development and economic transformation. He is also part of the World Economic Forum Expert Network Group focusing on Sustainable Development in Asia, and as environmental advisor to Sime Darby Holdings, is involved in implementing the environmental agenda for this multinational conglomerate based in Kuala Lumpur with operations across key growth industry sectors including Plantation, Property, Industrial, Motors, Energy and Utilities as well as Healthcare. Prior to this, he was a postdoctoral fellow with the Centre for Energy and Environmental Markets (CEEM). He continues to serve as a Stakeholder Council Member for the Global Infrastructure Basel Foundation, as a Global Advisory Board Member of Economists Without Borders and is the Curator of Global Shapers Kuala Lumpur, a not-for-profit organization focusing on creating sustainable impacts in Malaysia. He actively participates and contributes in various stakeholder platforms including the ‘Water for Growth’ initiative and the Integrated Urban Water Management task force seeking to develop a National Level Water Transformation Roadmap for Malaysia. He is a Climate Reality Leader trained by Al-Gore, former Vice President of the USA, in Pittsburgh. He was the recipient of the Yayasan Sime Darby Scholarship, Cambridge Bursary Scholarship, ARG Hermes Scholarship, Brookfield Multiplex Engineering Management Prize and the Australian Conferences Management Education for Engineers Award. For his work in sustainability, he was also named as one of Malaysia's Top 10 Most Inspiring Green Warriors, 100 Visionary Young Leaders Leading Us Towards a Better World by Real Leaders Magazine, received a Forbes Fellowship, was a 2017 Augustman A-Lister and bestowed with the Ten Outstanding Young Malaysians (TOYM) Award for Environmental Leadership. He is also named as a Young Leader of the World Cities Summit a select group of change-makers from diverse sectors working on shaping the global urban agenda and a 2018 Asia 21 Young Leaders. His work has been featured across a number of mainstream media such as The Star, New Straits Time, The Edge, Focus Malaysia, Malaysia Tatler, Malaysia SME, Korean Times, Kuwait Times among others. On this episode we will hear from Dr. Siew: About his background, how he became interested in engineering, economics, and how he finds himself in 2019 at the epicenter of the global climate change movement. His goals for “future-proofing” our planet and keeping global temperatures within the 1.5 degrees Celsius critical change mark. His experiences working for a large natural resources company as sustainability advisor. His ideas for promoting entrepreneurship to address climate change and sustainability. His views towards how society must adapt and create better environments for the aging population within the "built environment" system. For all the relevant links corresponding to this interview please visit www.radioideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. David Fajgenbaum, Assistant Professor of Medicine in the Division of Translational Medicine & Human Genetics at University of Pennsylvania, Associate Director, Patient Impact of the Penn Orphan Disease Center, Founding Director of the Castleman Disease Center, and Co-Founder & Executive Director of the Castleman Disease Collaborative Network (CDCN). Ira Pastor Comments: A rare disease is defined as any disease that affects a small percentage of the population. In the United States, the Rare Diseases Act of 2002 defines rare disease strictly according to prevalence, specifically "any disease or condition that affects fewer than 200,000 people in the United States", or about 1 in 1,500 people. This definition is essentially the same as that of the Orphan Drug Act of 1983, a federal law that was written to encourage research into rare diseases and possible cures. In Japan, the legal definition of a rare disease is one that affects fewer than 50,000 patients in Japan, or about 1 in 2,500 people. The European Commission on Public Health defines it meaning fewer than 1 in 2,000 people, but contains some cut-offs for diseases that are not chronically debilitating or inadequately treated. The US organization Global Genes has estimated that more than 300 million people worldwide are living with one of the approximately 7,000 diseases they define as "rare" per the United States definition. Chronic genetic diseases are commonly classified as rare, and among the 7000 conditions mentioned above, rare diseases may result from bacterial or viral infections, allergies, chromosome disorders, degenerative and proliferative causes, and may effect any body organ. Dr. David Fajgenbaum Today's guest, who I'm honored to have join us to further delve into this topic, not just from the perspective of a clinician and investigator, but also as a patient himself, is Dr. David Fajgenbaum, MD. Dr. Fajgenbaum earned his MD from the Perelman School of Medicine at the University of Pennsylvania, and is an Assistant Professor of Medicine in the Division of Translational Medicine & Human Genetics at Penn, Associate Director, Patient Impact of the Penn Orphan Disease Center, Founding Director of the Castleman Disease Center at Penn, and Co-Founder & Executive Director of the Castleman Disease Collaborative Network (CDCN). Dr. Fajgenbaum leads the Castleman Research Program at Penn as principal investigator of 18 translational research studies, including an international natural history study and the first-ever NIH funded research of idiopathic multicentric Castleman disease (iMCD). His published research has changed the way iMCD is researched and treated and as a patient himself, is in his longest remission ever thanks to a precision treatment that he identified. He is also the author of Chasing My Cure: A Doctor's Race to Turn Hope Into Action Dr. Fajgenbaum co-founded the Castleman Disease Collaborative Network in 2012 to accelerate research and treatments for Castleman disease through a 'Collaborative Network Approach,' a business-inspired approach to biomedical research, which has become a blueprint for advancing rare disease research. Dr. Fajgenbaum is also the Co-Founder of the National Students of AMF Support Network (Actively Moving Forward), a non-profit organization dedicated to supporting grieving college students due to a loved one's diagnosis or death (or their own diagnosis) of a terminal illness. He co-authored "We Get It: Voices of Grieving College Students and Young Adults," a book for grieving college students and those who wish to support them. Dr. Fajgenbaum's work has been highlighted by the New York Times, Science, Today Show, Reader's Digest, Forbes Magazine, Perelman School of Medicine, World Affairs Council of Philadelphia, College of Physicians of Philadelphia, Everylife Foundation, Global Genes, and the University of Colorado. Dr. Fajgenbaum also received his MBA from Penn, at The Wharton School, where he was awarded the Joseph Wharton Award, Core Value Leadership Award, Kissick Scholarship, Wharton Business Plan Competition Social Impact Prize, Eilers Health Care Management Award, Mandel Fellowship, and Commencement Speaker., where he was a 21st Century Gamble Scholar. On this show we will hear about: Dr. Fajgebaum's background and life before his diagnosis with Castleman's disease, and his interest in becoming a doctor. The events surrounding his diagnosis with Castleman's disease in 2010. His discovery in 2012 of his own personal therapeutic regimen that helped put him into remission. His development of the Castleman Disease Collaborative Network. A discussion of drug "re-purposing" in the area of rare diseases. Finally, a discussion of his future research visions in the rare disease space.   visit www.radioideaxme.com for all of the links. ideaXme is a global podcast, creator series and mentor programme. Mission Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interview Dr. Lorna Harries, Professor of Molecular Genetics at University of Exeter Medical School. Ira Pastor Comments Today as we continue our discussions on ideaXme pertaining to the biological hierarchy of life, we are going to journey into what I refer to as the "metabolic architecture of the cell", and all of the fascinating dynamics that surround our genomes and allow the information encoded within to impact the on-going physiological states of our health, disease, and aging processes. In doing so we will segue into a discussion around a category of biologic entities, broadly known as Ribonucleic acids (or RNA). RNA RNA is a polymeric molecule essential in various biological roles including coding, decoding, regulation and expression of genes. Cellular organisms use one of the primary forms of RNA, messenger RNA (mRNA) to convey genetic information from our DNA to direct synthesis of specific proteins integral in appropriate gene expression across our cell lineages. RNA silencing or "RNA interference" (RNAi) is the process by which protein production from a gene is turned off. The term "RNA therapeutics" means either the use of one of the other forms of regulatory RNAs (e.g., siRNAs, microRNA) directly as a therapeutic agent and/or the modulation of RNA-based processes with more traditional drugs (e.g. small molecules). Because RNA is central to all biological processes, there are numerous potential avenues for addressing human disorders at the RNA level including many chronic degenerative diseases, infections, and even aging processes themselves. Our guest today, who is an expert in this unique domain of biology and is going to take us further into the topic, is Professor Lorna Harries, Professor of Molecular Genetics, University of Exeter Medical School. Dr. Lorna Harries Dr. Harries has a PhD in Molecular Genetics from University College London, and set up the "RNA-Mediated Mechanisms of Disease Group" at the University of Exeter Medical School in 2006. Her team has a special focus on how RNA biology can influence both normal and disease states, from large-scale "omics" approaches, down to detailed assessment of specific mechanisms in specific genes. Dr. Harries leads the group's investigation into how and why we age, and the reason age is a major risk factor in diseases like Type-2 Diabetes. Her goal is to use the information the group uncovers to develop a new generation of anti-degenerative drugs. As many age-related diseases have common roots, causes and mechanisms, which arise from the failure of a few basic health-maintenance mechanisms that decline in efficiency as we age, the Harries lab feels by focusing and by targeting them, they will eventually be able to target multiple age-related diseases at once. Dr. Harries has written over 90 peer-reviewed articles and was awarded the Diabetes UK RD Lawrence Prize Lectureship in 2011. She is coordinator of the annual UEMS "Men in White" school outreach with Dr. John Chilton, an event that brings in year 9 students from schools stretching from South Devon to North Somerset and gives them hands-on experience of work in a research laboratory. Dr. Harries is also is a STEMnet ambassador as well as an Exeter Catalyst Champion for Public Engagement. On this show we will hear from Dr. Harries: About her background, how she became interested in science, molecular biology, and how she finds herself at the forefront of RNA biology and therapeutics. The history of RNA therapeutics and why according to her recent Nature article "It's Time for Scientists to Shout About RNA Therapies." An overview of RNA splicing, the spliceosome, splicing factors, and their respective roles in human ageing. Her work in RNA regulation of human cellular senescence. Her work in RNA regulation of Type-2 Diabetes. Her future visions for her work. Dr. Lorna Harries will be speaking at the following upcoming conferences: 6th Annual Middle East Diabetes Conference Dubai 29-30 Jan 2020 Splicing 2020 meeting Capirica 12-16 July 2020  Allergan Science of Aging meeting Monaco 30th March - 1st April 2020 (dates provisional!) Longevity Leaders London April 21-22 2020  

Join Brandon and Ali in an admittedly "down the rabbit hole" discussion regarding the legitimate upcoming experiment conducted by a stem-cell research company to bring the dead back to life and the downright insane experiments conducted on US citizens by the US government during MK Ultra.    https://www.youtube.com/watch?v=Z9GlB0TPDp4https://www.statnews.com/2017/06/01/brain-death-trial-stem-cells/and as always, we want to give credit to our intro music.  Cut portion of Evening of chaos by Kevin MacLead.  Music from https://filmmusic.io https://incompetech.com License CC BY http://creativecommons.org/licenses/by/4.0 

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark interviews Alan Seid, presidential candidate for The Republic of Palau. Today, on ideaXme we are going to talk about the topics of micro-states, island nations, and innovation. ideaXme has no political affiliations and does not endorse this presidential candidate. Mr. Alan Seid started his political career at a young age of 23 where he became part of the movement to promote Palau's Independence from the US. He was able to join the team that negotiated the Compact of Free Association of which Palau gained its Independence from the Trust Territory of the Pacific Islands to become a full member of the United Nations. He was elected to serve in the Palau House of Delegates in 1988 and served in that role for 3 terms for a total of 12 years. He then followed that as a member of the Palau Senate for one term. Currently, Mr. Seid has begun a run for the Presidency of Palau. (The ideaXme show does not endorse political candidates of parties). His extensive innovation centric platform includes, but is not limited to: The development of Palau as a hub for regenerative medicine and medical tourism in the region; the development of the medical cannabis production value chain in Palau and for export; novel, innovative, regional appropriate, eco-cleanup and renewable energy initiatives, with emphasis on Greenway Revolution technology and products, and Dr. Elaine Wang, who is one of the Board members of Greenway Revolution joins him on the call; initiatives to empower the younger generation of Palauan entrepreneurs, to stay (or come back) to the island, by providing funds and business training; promoting the concepts of Palau becoming a financial center with the utilization of blockchain technology while setting up a favorable and efficient tax regime On this show we will hear from Mr. Seid His background, his interest in policy, in technology, and why he is running for the presidency of Palau. The importance of national sovereignty in executing on novel innovation goals. His thoughts on the development of Palau as a hub for regenerative medicine and medical tourism in the region. His thoughts on the development of the medical cannabis production value chain in Palau and for regional export. About Greenway Revolution technology and products. Finally, we will hear about his initiatives to empower the younger generation of Palauan entrepreneurs, to stay (or come back) to the island, by providing funds and business training.

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark interviews Dr Ameenah Firdaus Gurib-Fakim, biodiversity scientist and former President of Mauritius 2015-2018. Today ,we are going to touch on several themes from recent shows (including natural products, bio-diversity, conservation, innovation, Africa, island nations, and micro-nations) and bring them together for what is going to be an exciting episode Throughout the 20th century, natural products (primarily those from plants, fungi, and bacteria) formed the basis for a majority of all pharmaceuticals, biologics, and consumer healthcare products used by patients around the globe, generating trillions of dollars of wealth. However, many scientists believe we have only touched the surface of what the natural world, and its range of organisms could teach us. Lately, novel research disciplines, including inter-kingdom signalling and semio-chemical communication, the respective abilities of one species living signals to affect the genome of another, not to mention in-depth study of the micro-biome and virome, are highlighting entirely new ways that non-human bio-products can affect the human genome for positive transitions in health and wellness. Simultaneously, we are finding out more and more about the novel, combinatorial biochemical approaches that nature utilizes (as evolutionary dynamics would never follow the single magic bullet approach promoted by the pharma industry) to address multiple levels of the disease-biome simultaneously. Such integrated dynamics that nature uses, represent a major contrast when compared to the reductionist, highly siloed model at play in the pharma industry today. As current environmental disasters continue to remind us, hundreds of millions to billions of years of evolutionary knowledge locked up in such species, can be wiped out and lost forever- so we need to keep this in mind as we efficiently tap this treasure trove of potential in the 21st century Dr. Ameenah Firdaus Gurib-Fakim is a Mauritian biodiversity scientist and politician who served as the President of Mauritius from 2015 to 2018.  Her autobiography is entitled "Ameenah Gurib-Fakim: My Journey". Dr. Gurib-Fakim is the first woman elected as President of the country and is the third woman to have served as Head of State following QE2 and Monique Ohsan Bellepeau. She graduated from the University of Surrey in 1983 with a BSc degree in chemistry. After obtaining her PhD degree in organic chemistry at Exeter University, she returned home in 1987 to take employment at the University of Mauritius, where she was a Professor with a chair in Organic Chemistry. She served as Dean of the Faculty of Science and Pro Vice Chancellor.She also worked at the Mauritius Research Council as Manager for Research (1995-1997). She worked as Managing Director of CIDP Research & Innovation (formerly Cephyr, Centre for Phytotherapy Research) and had been involved in publishing several scientific books / chapters in books on related topics including but not limited to: Mauritius through Its Medicinal Plants: towards a better understanding of medicinal plants of the Indian Ocean Islands; Novel Plant Bioresources: Applications in Food, Medicine and Cosmetics; Chemistry for Sustainable Development in Africa; Floral Biodiversity of the Mascarene Islands; Medicinal and Aromatic Plants of the Indian Ocean Islands, and Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components: Harnessing Traditional Knowledge to Treat Existing and Emerging Infectious Diseases in Africa, She served as the Chairperson the International Council for Scientific Union Regional Office for Africa (2011 -2014) prior to her Presidency of Mauritius Dr. Gurib-Fakim has also been the recipient of international awards including the L'Oreal-UNESCO Award for Women in Science, Laureate for the National Economic and Social Council, the Technical Centre for Agricultural and Rural Cooperation and New Partnership for Africa's Development for African Women in Science and the African Union Award for Women in Science. She was also made Commander of the Order of the Star and Key of the Indian Ocean (CSK) by President Anerood Jugnauth in 2008 for her contribution in the education and the scientific sector.  She was awarded the Order of the Chevalier de Ordre des Palmes Academiques by the Government of France in 2009. Upon becoming President, she was elevated to the highest civilian award of Grand Commander of the Star and Key of the Indian Ocean (GSCK). In 2015, she was named the vice-chairman and trustee of the Planet Earth Institute. Here, Dr. Gurib-Fakim talks of:  - About her background, how she developed an interest in science, in chemistry, in phyto-medicine, in environmentalism, and in politics, and how she rose to prominence in the Mauritian political system - About her vision regarding the world needing "real policies for properly communicating science to the people - About her vision for Africa becoming a supplier of human talent and capital to the world.  - About her views on African sustainable development - About her future plans For all the links relating to this show please visit www.radioideaxme.com ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ideaXme Ltd.    

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr. Manabu Kinoshita, Associate Professor of Immunology, Department of Immunology and Microbiology, at the National Defense Medical College in Tokorozawa, Saitama, Japan. Blood Transfusions Today the ideaXme show is going to travel around the world to Japan, to discuss the topic of artificial blood technology. Blood transfusions save lives and improve health, but many patients requiring transfusion in 2019 still do not have timely access to safe blood. The need for blood transfusion may arise at any time in both urban and rural areas. The unavailability of blood has led to deaths and many patients suffering from ill-health. Blood loss from traumatic injuries is responsible for thousands of deaths annually, and even when people survive, oxygen depletion can leave tissue permanently injured. Fresh blood can only be stored for 42 days, and only lasts for a few hours un-refrigerated. Currently, if you need to receive a blood transfusion, it must also be matched specifically with your blood type or the "universal donor," type, O negative. An adequate and reliable supply of safe blood is normally assured by a stable base of regular, voluntary, unpaid blood donors, and they are also the safest group of donors as the prevalence of blood-borne infections is lowest among these donors. The World Health Organization (WHO) estimates that around 120 million units of donated blood are collected globally every year. 42% of these blood donations are collected in high-income countries, home to less than 16% of the world's population. Blood Substitute A blood substitute (also called artificial blood or blood surrogate) is any substance that can be used to mimic and fulfill some functions of biological blood. It aims to provide an alternative to blood transfusion, which is transferring blood or blood-based products from one person into another. Thus far, there are no well-accepted oxygen-carrying blood substitutes, which is the typical objective of a red blood cell transfusion; however, there are widely available non-blood volume expanders for cases where only volume restoration is required. A full substitute could be vital in settings like battlefields or rural areas without easy access to blood, used as a stopgap measure to keep the injured alive until they get to a hospital. Also, a one-size-fits-all blood substitute would overcome all sorts of existing obstacles, ranging from not enough donations by ethnic minorities, to finding matches for rare blood types. Dr. Manabu Kinoshita Today's guest joining us to go further into this topic, to discuss the challenges and possibilities of achieving a universal blood substitute, is Dr. Manabu Kinoshita, Associate Professor of Immunology, Department of Immunology and Microbiology, at the National Defense Medical College in Tokorozawa, Saitama, Japan. Dr. Kinoshita is a surgeon who specializes in both immunology (with a focus on host-defense dynamics against surgical stress) as well as nano-medicine, including red blood cell substitutes, platelet substitutes, and nanosheets for Biological Applications such as wound healing. The National Defense Medical College is Japan's six-year university-level military academy under control of the Ministry of Defense whose objectives are to train future military officers who are also medical doctors and current military doctors. Students graduate with an advanced level of theory and application of medical sciences required to conduct the missions of the Japan Self-Defense Forces and acquisition of research capability of the related fields as well as to offer training of clinical medicine. On this who we will hear from Dr. Kinoshita: About his background and interest in surgery, trauma, and the focus on artificial blood substitutes. An introduction to the work of the National Defense Medical College. His recent work and discoveries about his artificial blood product, profiled in the Journal of Transfusion paper entitled Combination Therapy Using Brinogen-chain peptide-coated, ADP-encapsulated Liposomes and Hemoglobin Vesicles for Trauma-induced Massive Hemorrhage in Thrombocytopenic Rabbits. His future visions for the project, and other research projects he is working on. For all the relevant links for this interview please visit www.radioideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Daniel Addario, former Special Agent in Charge for the U.S. Drug Enforcement Agency.   On a few previous shows we touched on the global problem of drug abuse (of both legal and illegal drugs) primarily looking at the problem from a therapeutic perspective, specifically related to opiate withdrawal technologies. But the problem is much bigger than that.   According to the U.S. National Survey on Drug Use and Health, an estimated 20 million American adults battled a full-fledged substance use disorder in 2017.   Drug abuse and addiction cost American society more than $740 billion annually in lost workplace productivity, healthcare expenses, and crime-related costs.   Globally, the numbers escalate even further off the charts.   It is a war of amazing proportions, with many different battle fronts, some of which we are winning, some not so much, but it is one that is always changing and that we need to stay ahead of.   That’s why I’m so honored to be joined by our guest today, a gentleman whose career is something that it would take several movies and a few mini-series to appropriately encapsulate.   Mr. Daniel Addario spent close to 3 decades with the U.S. Drug Enforcement Agency (DEA), rising to the role of Special Agent in Charge, the highest-ranking field agent for the DEA under five presidents, heading up anti-drug operations in 13 countries throughout South American, South East Asia, as well as in the U.S.   He started his career in Philadelphia as one of the nation’s first narcotics undercover agents in 1954 and was involved in the capture of some of the world’s most notorious drug lords, and was even on scene when Panamanian strongman Manuel Noriega was captured by US forces.   His dossier of adventures consists of, but is not limited to:   A cultivation of the U.S. strategic relationship with the Panamanian leader, Manuel Noriega, who at the time, was head of police in Panama and fighting the war on drugs with the U.S. The chase and capture Auguste Joseph Ricord, the French-Corsican heroin trafficker and one of the founding members of the French Connection, immortalized in the 1970s Gene Hackman movie. Visiting the center of the “Golden Triangle” opium empire of Burmese opium king Khun Sa to discuss poppy crop eradication and substitution. The major drug bust, round up and arrest of dozens of Hell’s Angels, including their head Sonny Barger. The destruction of a dozen of drug guru Timothy Leary’s LSD labs. The drug arrest Ray Charles. Intermingling with special counsel Robert Mueller, Frank Sinatra, and Watergate figures including John Dean and Gordon Liddy.   Sadly, in 1993 the very scourge he was battling came home and was responsible for taking the life of his son Daniel due to opiate addiction.   After he retired from the DEA, Mr. Addario spent some time in the news business working for a San Francisco news station.   He has recently published a book entitled Chasing the Dragon: How to Win the War on Drugs where is recounts his long history and experience as well as puts forth a range of new ideas as the drug war continues in this millennium.   On this show we will hear from Dan:   About his background, where he grew up, how he became interested in law enforcement, and his amazing path from his first undercover street assignment to being at the epicenter of the capture of drug kingpins, warlords, and dictators. His thoughts on the legalization and decriminalization of marijuana. His thoughts on holding doctors and big pharma accountable for the opioid epidemic. His thoughts on crop substitution programs. His thoughts on the Philadelphia Safehouse program. His thoughts on CIA and State Department interference in the DEAs operations.

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr Wise Young M.D., Ph.D., the Richard H. Shindell Chair in Neuroscience, Distinguished Professor of Cell Biology & Neuroscience and the Founding Director of the W. M. Keck Center for Collaborative Neuroscience at Rutgers University.   Spinal Cord Injury   A spinal cord injury (SCI) is defined as any damage to the spinal cord that causes temporary or permanent changes in its function.   Symptoms may include loss of muscle function, loss of sensation, or autonomic function in the parts of the body served by the spinal cord below the level of the injury. Injury can occur at any level of the spinal cord and can be a complete injury, with a total loss of sensation and muscle function, or incomplete, meaning that some nervous signals are able to travel past the injured area of the cord.   Depending on the location and severity of the damage, the symptoms vary, from numbness to paralysis to incontinence. Long term outcomes also vary widely, from full recovery to permanent quadriplegia or paraplegia. Complications can include muscle atrophy, pressure sores, infections, and breathing problems.   Direct medical expenses for spinal cord injuries can run into millions of dollars (not including lost wages and earning potential) and can include: spinal surgery, trauma care (use of a ventilator) rehabilitation (including physical and occupational therapy, speech therapy, and mental health counseling), long-term care, including the costs of in-home aides, medical equipment such as wheelchairs, and medication such as painkillers and antibiotics.   A recent estimate showed that there are about 18,000 new SCI cases each year in the U.S. and the number of people with SCI living in the United States is around 290,000.   Dr. Wise Young   Today’s guest is going to take us further into the area of spinal cord injury as well as discussing some of the most exciting work that’s going on in the development of innovative therapeutic intervention for SCI. Today’s speaker is Dr. Wise Young, who with a Doctorate in Physiology and Biophysics from the University of Iowa, and a medical degree from Stanford University has committed himself to bringing innovative treatments to people with spinal cord injuries over the last few decades.   Speaking on how he felt compelled to work in tackling spinal cord injuries, Dr. Young expresses how “I was an intern at Bellevue Hospital when I took care of my first spinal cord injury patient. It was very emotional for me because I think one of the things that all doctors hate to feel is helpless, to feel as if there's nothing you can do.”   He continues, “this is really one of the most hopeless conditions in human history where patients are told that they will never walk again. And so, I decided to take on a subject that I think most of my colleagues believed would be a waste of time.”   Inspired by the hopelessness of the condition, he went on to build and train a twenty-five center clinical trial network in China, Taiwan, and Hong Kong where Phase II human clinical trials using umbilical cord blood mononuclear cells and lithium are currently on-going. Today, he is working on establishing clinical trial networks in the United States, Norway, and India.   Dr. Young led the team that discovered and established high-dose methylprednisolone (MP) as the first effective therapy for spinal cord injuries. This 1990 work upended concepts that spinal cord injuries were permanent, refocused research, and opened new vistas of hope.   He also developed the first standardized rat spinal cord injury model used worldwide for testing therapies, formed the first consortium funded by the National Institutes of Health (NIH) to test promising therapies, and helped establish several widely accepted clinical outcome measures in spinal cord injury research.   Speaking on the development of the Phase II trials, Dr. Wise explains how he first witnessed them take place in Kunming, China. “There was an army hospital there that really did something very unusual. They were taking patients after spinal cord injury and walking them six hours a day, six days a week for six months. It was called the six, six, six program. This caused many of the patients to recover function, I mean, as many as half of the patients recover walking.”   Dr. Young founded and served as editor-in-chief of the Journal of Neurotrauma.He organizedthe International and National Neurotrauma Societiesas forums for scientists to collaborate on in the areas of spinal cord injury and brain research. He served on advisory committees for the NIH, National Academy of Sciences, and National Institute of Child Health and Human Development, and on many spinal cord injury advisory boards.   His work has been featured in numerous national and international news and print publications including appearing on20/20 with Barbara Waltersand Christopher Reeve, Today with Katie Couric, 48 Hours, Fox News, CNN, and USA Today. TIME Magazine named Dr. Young America’s best in spinal cord injury research.   Some of his many honors include: being the first researcher elected to the Spinal Cord Injury Hall of Fame, receiving NIH Jacob Javits Neuroscience "Cure" Award, a Trustees Award for Excellence in Research, an Asian American Achievement Award, and The Hope Award.   On this show we will hear from Dr. Young:   About his background, how he got interested in science, physiology and medicine, and how he finds himself at the epicenter of neuroscience and trauma care. He will discuss his cell therapy approaches in SCI and his supportive interventions in SCI. He will also talk about his "morphodynamic" interventions in SCI and go into his international work in Asia and Norway.   ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.  

Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. Virginia Byers Kraus, Professor of Medicine, Pathology, and Orthopaedic Surgery, and a faculty member of the Duke Molecular Physiology Institute in the Duke University School of Medicine. Ira Pastor Comments: Arthritis is a term often used to mean any disorder that affects joints (the most common forms being osteoarthritis (OA) and rheumatoid arthritis (RA)), where symptoms generally include joint pain, stiffness, redness, warmth, swelling, and decreased range of motion. In some types of arthritis (on the auto-immune side of things) other organs can be affected, and onset of arthritis can be gradual or sudden. There is no known cure for either rheumatoid or osteoarthritis. Joint replacement surgery may be required in eroding forms of arthritis. Treatment options vary depending on the type of arthritis and can include physical therapy, lifestyle changes (including exercise and weight control), orthopedic bracing, and various medications which can help reduce inflammation in the joint (and immune responses in case of auto-immune forms of arthritis) which can help decrease pain and potentially slow the rate of joint damage, hopefully to "zero", which is the nature of the current class of “holy grail-ish” type drugs in the Rheumatoid Arthritis space known as Disease Modifying Anti-Rheumatic Drugs (DMARDs). No drug fulfilling the criteria for a "Disease Modifying Osteoarthritis Drug " (or DMOAD) is approved by the regulatory agencies such as the FDA or EMEA. But whether one is looking for a DMOAD, or looking beyond the current state of the art of the DMARDs to the next RA holy grail type intervention, many thought leaders would agree that it would be a form of intervention that stimulates Chondrogenesis, or the process by which new fresh cartilage is created in the joint, literally reversing the pathogenesis of such diseases, as opposed to just slowing or stopping them. Once damaged in humans, cartilage has very limited repair capabilities. Because chondrocytes are bound in lacunae, they cannot migrate to damaged areas. Also, because hyaline cartilage does not have a blood supply, the deposition of new matrix is slow. Damaged hyaline cartilage is usually replaced by fibrocartilage scar tissue instead. But this is not the case in other species such as newts and zebrafish, where fresh cartilage is regrown and regenerates perfectly over a lifetime. Today’s guest who is going to take us further into all these themes is Dr. Virginia Byers Kraus. With an MD and PhD from Duke University, Dr. Kraus is Professor of Medicine, Pathology, and Orthopaedic Surgery, and a faculty member of the Duke Molecular Physiology Institute in the Duke University School of Medicine. She is a practicing Rheumatologist with 20 years’ experience in Osteoarthritis research. Dr. Kraus is past president of the Osteoarthritis Research Society International (OARSI), the premier organization focused on the prevention and treatment of osteoarthritis through the promotion and presentation of research, education, and the worldwide dissemination of new knowledge. In 2019, she was elected to the Association of American Physicians and awarded the Lifetime Achievement Award from OARSI. She is co-principal investigator of the OARSI/Foundation for NIH Osteoarthritis Biomarkers Consortium Project, which advances the validation and qualification of biomarkers for OA diagnosis, prognosis, and clinical trials. She also directs the Duke Biomarkers Shared Resource which is a facility that assists investigators with the design and implementation of molecular and protein assays to evaluate biochemical and inflammatory markers. Dr. Kraus is also the Director of the Molecular Measures Core in the Center for the Study of Aging and Human Development. On this show we will hear from Dr. Kraus: How she developed an interest in science, medicine, and rheumatology. The importance of appropriate biomarker development, validation and qualification in the diagnosis, prognosis, and development of effective interventions in arthritis. Her recent paper entitled Analysis of “Old” Proteins Unmasks Dynamic Gradient of Cartilage Turnover in Human Limbs, in which she highlights the discovery of interesting protein / microRNA constituency differences of various joints of the body, leading to clues for different regenerative medicine interventional possibilities. Finally, we’ll discuss her work in the Molecular Measures Core in the Center for the Study of Aging and Human Development where her group is focused on "understanding the means to optimize whole person reserve and resilience through analyses of molecular factors indicative of cellular and tissue level ability to withstand and recover from stressors.” ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews evolutionary biologist, researcher, and author, Dr. Josh Mitteldorf. Ira Pastor Comments: On the last couple of shows we’ve been spending a lot of time on the different hierarchical levels of the aging processes, talking about the genome, the microbiome, tissue engineering, systems biology, and many other topics, and we’ve been speaking to a broad range of thought leaders in these various fields. As the study of aging and longevity as areas of biotherapeutic interventions has become more popular in recent years, an extensive catalogue has grown, and continues to grow, with everyone’s key aging hallmark, or damage target of interest, piling on the mix. This lengthy list, many of which we’ve touched on during the show, currently includes, but is not limited to, the following: inflammation, oxidation, heat shock, microbial burden, xeno-toxin accumulation, somatic mutations to the genome, epigenetic modifications, stem cell exhaustion, senescence cell accumulation, damaged mitochondria, telomere variability, ECM cross-linking, nutrient sensing dysfunction, intra / extra-cellular aggregates / junk accumulation, and so on. While this list, no doubt, contains a wide variety of fascinating topics connected to health and aging, and areas for potential intervention that may improve outcomes in various disease states associated with aging, we still have not yet touched on a unified picture of why we age in the first place. In addition, we have not yet touched on many of the paradoxes that get swept under the rug that challenge a lot of the ingrained doctrine in longevity biomedical research. These paradoxes include: Why do some extremely damaged organisms live long healthy lives? Why do some pristine organisms drop dead in the prime of life? Why are all of these aging hallmarks, or forms of damage, that I have listed above, not only found in elderly, decrepit, disease ridden individuals, but also happen to be all found (some to a much greater degree proportionately) in the earliest stages of life in developing embryos and fetuses? We still have an incomplete big picture of aging and that’s no good if we want to truly intervene in it. That’s why I’m so happy that joining us today to take us deeper into this topic, and expose us to some truly fascinating ideas and theory, is Dr. Josh Mitteldorf. After earning a PhD in astrophysics at University of Pennsylvania and spending a decade or so in that field, as well as in the areas of optical design and energy conservation, Dr. Mitteldorf made a move and transitioned into the field of evolutionary biology and currently studies evolutionary theory of aging using various computer simulations. He has spent a lot of time over the years looking to correct what he feels is a fundamental error in the foundations of evolutionary theory where he feels that evolutionary biologists had focused too much on the "selfish gene theory" (the gene-centered view of evolution that purely holds that adaptive evolution occurs through the differential survival of competing genes), and not enough on the ecological context surrounding those organisms and their genes, which he feels has everything to do with why we age and, by extension, what we have to do to stay healthy as we get older. Over the years he has lectured extensively at universities including Harvard, MIT, Berkeley, Bryn Mawr, LaSalle and Temple. He’s the author of two books on the topic including Cracking the Aging Code: The New Science of Growing Old - And What It Means for Staying Young and Aging is a Group-Selected Adaptation: Theory, Evidence, and Medical Implications. He also is responsible for the “Aging Maters / Playing the Game for a Longer Life” blog, which is truly an encyclopedic resource for all things happening in the longevity biotech space. He is also creator of the Data-BETA project, a project conducted in cooperation with the UCLA laboratory of Steve Horvath, to study the synergy of various different supplements and drug interventions, designed to find the rare combinations that work together to produce a big anti-aging benefit. On this show we will hear from Dr. Mitteldorf: About his background and what it is like to be astrophysicist in the world of evolutionary biology and aging. His aging theories. The Data-BETA Project. His other passions including meditation, yoga, music, environmentalism, and campaigning for a smoke-free / tobacco-free world. For the full text with links please visit www.radioideaxme.com. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. William Pruett, from the Physiology and Biophysics Department, of the University of Mississippi Medical Center. Ira Pastor Comments: The year is now 2019, and we have surpassed $7 trillion in total annual healthcare expenditures around the globe. As part of that $7 trillion, we’re now spending close to a $1 trillion a year on pharmaceutical products. As we’ve been watching the traditional pharma product basket change over the last century, form small organic molecules drugs and vaccines, to larger macromolecule biologics (proteins and antibodies), and now into an era of gene and cell therapies, and other therapeutic modalities, the tools that allow these discoveries and development of these novel interventions have been changing as well. A set of tools that we have been hearing quite a bit about (and that we have discussed a bit on the show) in recent years is the triad of artificial intelligence, machine learning, and deep learning and their respective applications in the drug discovery and development processes. And a term we have heard a lot mentioned alongside these tools is that of “In-Silico” - an expression meaning "performed on computer" or "via computer simulation" in reference to different biological experiments. We’ve talked about a few of these applications on past shows, in terms of using some of these tools to better guide the rational drug design process, or more appropriately select patients for a clinical trial, via personalized medicine. But we have yet to address the "800-pound gorilla" in the room, and that is that even after you have your "perfect" drug candidate and your "perfect" inclusion / exclusion criteria, traditional clinical trials still cost billions of dollars and take many years of hard work, with no guarantee that your new drug will make it through the complexity that is represented by the human body, with its 30 trillion cells, its endless array of heterogenic micro-environments, wide range of gene expression, and so forth. But what if this wasn’t the case in the future? What if it was possible to conduct "In-Silico" clinical trials on virtual bodies that could perfectly mimic human physiology? Today we are joined by Dr. William Pruett, from the Physiology and Biophysics Department, of the University of Mississippi Medical Center. With a Doctorate in Mathematics from Baylor University, Dr. Pruett has been merging his skills from Mathematics (including expertise in representation theory, geometry, combinatorics, numerical analysis and algorithms) with an in-depth understanding of cardiovascular, renal, and endocrine physiology. Dr. Pruett’s research interests include the use of physiological modeling to generate hypotheses and to understand integrative physiological mechanisms that are not observable in either whole animal or human experiments. For almost 50 years, his department has been developing computer simulations of integrative physiology for both research and educational purposes. The current model, HumMod, is comprised of 14 organ systems, and includes neural, endocrine, circulatory, and renal physiology. HumMod provides a top-down model of human physiology from whole organs to individual molecules. It features more than 1,500 equations and 6,500 variables such as body fluids, circulation, electrolytes, hormones, metabolism, and skin temperature. HumMod aims to simulate how human physiology works and is currently the most sophisticated mathematical model of human physiology ever created. On this show we will hear from Dr. Pruett: How he became interested in mathematics, physiology, and in merging the two together. An overview of Hummod and how it works. Hummod's use in understanding renal physiology and pathophysiology of hypertension. Other therapeutic indications he and his partners are working on. Finally, his future visions of In-Silico clinical trials. ideaXme is a global podcast, mentor programme and creator series. Mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. Per Borghammer, Clinical Professor in the Department of Clinical Medicine, Nuclear Medicine and the Positron Emission Tomography (PET) Center at Aarhus University in Denmark.   Ira Pastor Comments:   On past shows we have touched on the topic of systems biology, a field of study that looks at the interactions between components of biological systems, and how these interactions give rise to the function and behavior of that system, and the respective biological processes whether that be growth, development, aging, disease, or degeneration.   On other shows, we’ve also touched on the microbiome and virome, as well as the connection between various microorganisms, either directly, or via the immunomodulatory and/or auto-immune effects that may occur from being exposed to them, on the downstream development, progression, or in some cases control of chronic diseases such as Alzheimer’s and Diabetes.   And lastly, we’ve touched on the topic of “inflamm-aging;” this chronic progressive increase in the proinflammatory status across your body as you get older.   Today we are going to continue along at the intersection of these interesting themes in relation to the topic of Parkinson’s Disease (PD).   Parkinson's Disease is a long-term degenerative disorder of the central nervous system (affecting an estimated 6 million people globally) that mainly affects the motor system. The symptoms usually emerge slowly, which in early disease typically manifest as shaking, rigidity, slowness of movement, and difficulty with walking, and these main motor symptoms are collectively called "parkinsonism", or a "parkinsonian syndrome."   The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain which results in not enough dopamine in this region of the brain. The cause of this cell death is poorly understood, but it involves the build-up of proteins (a main one being alpha-synuclein) into abnormal aggregates called Lewy bodies in the neurons.   As the disease worsens, non-motor symptoms become more common and thinking and behavioral problems may also occur. Dementia becomes common in the advanced stages of the disease. Depression and anxiety are also common, occurring in more than a third of people with PD. Other symptoms include sensory, sleep, and emotional problems.   The cause of Parkinson's Disease is unknown but is believed to involve both genetic and environmental factors. Those with a family member affected are more likely to get the disease themselves. There is also an increased risk in people exposed to certain pesticides and among those who have had prior head injuries, while interestingly there is a reduced risk in tobacco smokers and those who drink coffee or tea.   Our guest today is going to take us down the path of a fascinating new theory that in certain cases of Parkinson's Disease, this horrific degenerative CNS disorder, might actually arise not in the CNS at all, but in the intestinal system and from there migrate to the brain.   Dr. Per Borghammer, is Clinical Professor in the Department of Clinical Medicine, Nuclear Medicine and the Positron Emission Tomography (PET) Center at Aarhus University in Denmark.   With a PhD in Neuroscience and a medical degree from Aarhus, Dr. Borghammer specializes in a variety of Neurobiological research areas including the study of Parkinson's disease, Atypical Parkinson's, and other neurodegenerative brain disorder pathophysiology & imaging, imaging within the parasympathetic nervous system, and imaging of cholinergic signalling processes that occur in other pathologies such as prostate cancer and chronic inflammation.   He recently won the European Association of Nuclear Medicine's Marie Curie Award for a project entitled "Visualising Parasympathetic Denervation in Parkinson’s Disease."   Today we will hear from Dr. Borghammer:   How he became interested in science, medicine, and the intersection of nuclear medicine and neuroscience. The current state of the nuclear medicine research system. When and how the idea arose that PD may start in the gut and how he contributed to this finding. The difference between "brain-first" and "gut-first" PD pathology. What could be the initiating causes of gut-first PD. Finally, how we may bring gut-first PD under control. ideaXme global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd.

Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews Dr. Alice C. Parker, Dean's Professor of Electrical and Computer Engineering at the Viterbi School of Engineering, University of Southern California. They talk of Dr Parker's work to build a synthetic brain. Ira Pastor Comments: On the last several shows we have spent time talking to many people working on both "the cutting edge" and "the bleeding edge" as it pertains to the various emerging therapeutic and preventative technologies related to health, diseases and the processes of aging. In doing so we’ve had various guests on who are engineering and building new devices and machines for human enhancement, including bio-artificial hearts, kidneys, bionic prostheses, and exoskeletons. Building a Synthetic Brain Today, we are going to go a bit beyond the bleeding edge of things, into what sounds like science fiction and discuss the topic of "Building a Synthetic Brain." With a Ph.D. in Electrical Engineering for North Carolina State, Dr. Parker specializes in a diverse range of disciplines including biomimetic neuromorphic circuits, biomimetic stereo vision, retinal and cortical neuromorphic analog circuits, and nanotechnology. Dr. Alice C. Parker, who is building a synthetic brain: Dr. Parkerhas served as the Division Director for Computer Engineering, Dean of Graduate Studies, and Vice Provost for Research at USC. Extensively published, Dr. Parker's current research focuses on the Biomimetic Real-time Cortex project based off the National Academy of Engineering's Grand Challenge, "Reverse Engineering the Brain," to explore the questions of if, when and how an artificial brain could be constructed for so-called "whole brain emulation," which includes emulating the complexity of the individual neuronal computations, constructing systems on the scale of the human brain with billions of neurons and trillions of synapses, connecting the neurons for effective and efficient communication, and implementing plasticity, or the ability of the brain to change and grow as learning occurs. On the show we will hear from Dr. Parker: About her background, how she got interested in science, engineering, and this fascinating world of neuromorphic computer design. About the basic approach of the Real-time Cortex Project and the next steps in the research process.  Ira Pastor, ideaXme longevity and aging Ambassador and Founder of Bioquark. ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward!™ ideaXme Ltd. Follow @ideaxmon Twitter on Instagram @ideaxme Finally, we’ll gain insight into Dr. Parker’s vision for what these computers could actually be capable of accomplishing in the coming decades and if such computers could exhibit some degree of consciousness.    ideaXme is a global podcast, creator series and mentor programme. Mission: Move the human story forward! ideaXme Ltd.  

Today's episode on Redefining Medicine spotlights Joel Osorio, MD. Dr. Osorio is an innovative businessman with a distinct entrepreneurial mindset concentrated adding value on areas of Biotechnology (mRNA), Reprogramming & Regenerative Medicine for translational use in humans and a variety of clinical applications aimed for both the private and the public health sectors. Dr. Osorio is the Founder, President, and CEO of RegenerAge Clinic and RegenerAge Beauty initiatives for transnational implementations. Vice President and International Clinical Developer for Bioquark, Inc., Chief Clinical Officer and Co-Founder at Reanima Advance Biosciences Project. Founder and CEO at Dr. Jois®️ and BiorganicAging®️ initiatives. He is the Medical Advisor at The Cracking Monkey®️ and HairLogica®️. Chief Medical Officer at What Skin Needs™️/WSN International Pty. Ltd. Within the academic and educational fields, Dr. Osorio acts as the Executive Vice President: Chairman of the WAMS Americas Division, member of the WAMS Executive Council (WAMS Executive Board), a member of the WAMS Education & Training Board (ETB), a member of the WAMS Editorial Board, an Honorary Member of the Academy Faculty FWAMS, an Honorary Fellow of the Academy & is also a Senior Partner at WAMS, The World Academy of Medical Sciences. He also functions as the Chief Executive Officer and a Founder at The Reprogramming Medicine Association. Dr. Osorio has appeared on several occasions on International T.V. shows, newspapers, radio shows, online discussion panels and has published multiple articles and medical reviews. He has also been a speaker and panelist for a variety of conferences, seminars and public events related to his medical field expertise and related fields.

In this weeks episode McKenna and Zane get folklore on your ass and talk about the Wendigo and its deep roots in Native American mythology. But then Stephen King happened and his version is probably the one you know about. We discuss how wasps are turning our #spiders into #zombies just because you haven't been having enough nightmares lately and how zombie frogs have sexier voices than regular frogs. Zane discovers that the company Bioquark is quietly trying to bring the dead back to life and everyone's pretty freaked out because there's, like, ZERO press coverage about this GIANT pharmaceutical company LITERALLY trying to make ZOMBIES. Lastly, we do get to the new Pet Sematary movie and how it's better (or worse) than the original. (spoiler alert it's worse). Mystic Frightcast is a weekly podcast about horror movies and other scary stories like a GIANT PHARMACEUTICAL COMPANY CONDUCTING ZOMBIE RESEARCH IN SOUTH AMERICA WHERE THERE IS LITTLE TO NO GOVERNMENT OVERSIGHT hosted by a couple of queer dorks. Find us at mysticfrightcast.com or on Facebook, Instagram, and Twitter.

Monday Night - Amad Painter - and Theresa J Morris will cover and Ira will be here Monday Night!  Chief Executive Officer, Bioquark Inc. Ira S. Pastor - Chief Executive Officer – Bioquark Inc. (www.bioquark.com) - a novel life sciences company focused on inducible, endogenous regeneration and cellular repair, to bring an end to many of the most devastating ailments associated with human disease, degeneration, and death - 30 years of experience across multiple sectors of the pharmaceutical industry including pharmaceutical commercialization, biotech drug development, managed care, distribution, OTC, and retail; Served as VP, Business Development for drug development company Phytomedics Inc., raising $40 million of private equity, consummating over $50 million of licensing deals, and bringing lead drug candidate from discovery stage to Phase III development; Prior to that, employed by SmithKline Beecham Pharmaceuticals working in sales, marketing, and business strategy positions. Mr. Pastor has also served as Vice President of Corporate Development for the pharmacy benefit management company Prescription Delivery Systems (acquired by Cigna Health Insurance); MBA, Temple University; BS, Pharmacy, Rutgers University. He is also a Board Member of RegenerAge SAPI de CV, (www.regenerage.clinic/en/) a clinical company focused on expedited translational therapeutic applications of regenerative and rejuvenative healthcare interventions, the Reanima Project (http://www.reanima.tech), member of the Executive Council of the World Academy of Medical Science – WAMS (https://wams.online/our_team/ira-s-pastor/), and member of the World Economic Forum's Human Enhancement council (https://www.weforum.org/people/ira-pastor).

Richard welcomes the CEO of a life sciences firm to discuss his efforts to dramatically extend the human life span, including the possible health benefits of mosquito bites.   GUEST:  Ira Pastor is the CEO of Bioquark a life sciences company, developing proprietary combinatorial biologics for the regeneration and repair of human organs and tissues. Ian has over 30 years of experience across multiple sectors of the pharmaceutical industry including pharmaceutical commercialization, biotech drug development, managed care,  and distribution.  Ira is a member of the World Economic Forum's Human Enhancement council.

Ken Johnston Sr. Don Garrett, Begin with Theresa J Morris and the ACO Club. ACO for Allied Comman Organizers for our Members. We are membership driven. We are historians and archivists of our own UFO Secret Space program. We provide a platform for Secret Space command FOR EACH STORY. Taxonomy for Alienologists and Ufologists! ACO  PLATFORM for The Allied Command Officers to order in humanoid sentient intelligent being terms. LARP is Live Action Role Playing. The terms of Alienology have yet to be defined for various groups in cyberspace. We are sharing more UFO PSYCHIC  HEALING ARTS CONFERENCES than ever before. Our Associations of Friends in Social Media are gathering together to share cross-pollination of our Ancient Wisdom and New Thought Teachings in Cosmology. We share science, pseudo-sciences, philosophies and how to share who we are as a species. We share NEW HORIZONS COSMOS EXPO VISIONARIES.  We who share what part of space we all may relate too as energy origin with memories is a new way of communication. We share rejuvenation and reincarnation. We share past lives and soul purpose research for immortality.  We are a riddle inside a mystery inside an enigma! Alienology, Cosmology, Epistemology, Phenomenology, Pyramidology, Taxonomy, Ufology are Niche Genres in our present times of the Cosmos Universe, Multiverse, Metaverse, Xenoverse, Omniverse, Alphaverse, and Omegaverse. Invisible College and Metaphysics of the esoteric and exoteric. We will share what is educational entertainment for the ACO CLUB.  American Communications Online is sharing TJ Morris ET Radio Niche Genre Topics to consider in our events. How we share now is shaping our future for tomorrow! JOIN US as an ACO CLUB Member! ACO Association and UFO Association now supported by American Communications Online.

TJ Morris ET Radio by American Communications Online. Theresa J Morris Host, Janet Lessin, Co-Host, Aquarian Radio, Cosmos Expo, Ira S. Pastor, CEO of Bioquark, Jan Harzan, Executive Director of Mutual UFO Network (MUFON) as Visionaries.  Team Players in 2019 for future Events for the Public. Ancient to New Thought Events. Future  applications of human regeneration. Future  applications  of disease reversion  / cancer reversion.Future  applications  of age-reversal work,Reanimation, Biologic immortality,General pharmaceutical industry issues.(ie. no cures for diseases /suppressing cures? Compassionate user programs? ) We need tolook back a couple years at the honey bee colony collapse that was occurring to see an example of how small interventions can run out of control, etc.Other topics - biologic suspended animation research - bio-hibernation, quantum biology, all tangential topics - UFOS, life after death, military connections and  a special guest to drop by and schedule an interview for next week. We are building a team of American  Event Coordinators we can trust as members in our ACO Association and UFO Association to support our causes. Our main focus in our ACO Club of social media members with Theresa J Thurmond Morris is sharing our truth for the new history we are archiving in cyberspace. We are providing educational entertainment radio shows, webinars, and events to educate the public of our goodwill. We share as visionaries with a gathering for our future B2B profit and non-profit associations. We suggest associations which may benefit those who are truthseekers and ufo enthusiasts!! TJ Morris Agency.  We invited Jan Harzan, Executive Director of MUFON to drop by and tell us when he may be able to spend more time with our ACO & UFO Association and future shows with topics he wants to share! 

2018 is in the books and we have a lot to be thankful for. We had some amazing guests this year on the show - Ira Pastor, CEO of Bioquark joined us to discuss the possibility of humans living forever. A new correspondent in the field Ada Pinkerton joined our cast of characters. We visited three amazing breweries; 101 North, St. Florian's and Steetcar 82 (coming soon). The Mojo sisters were back again, their whole family in full effect. Amanda Karr regaled us with ghost stories. Spiritual Medium, Evanne Jordan mystified us with her knowledge of Steve's inner workings. And then there was of course, the always entertaining, rarely serious Sir Matthew who finally discovered his porcelain-skinned crush was right in front of his nose the whole time. And what's up with that archeologist Raul? The one in prison? Will he be back? And lest we not forget the oft-obscure, always bizarre Trapper who leaves random voicemails which I'll be honest are quite bizarre and not just a little. Additional thanks to some of the regulars - the Producer, Amie, Jason Reedy, Kelly Stravers, Jevon, Nick, Gaby and of course Oisin, our Irish beer expert. Special thank you to first-timer Marc Ellis for his awe-inspiring knowledge on our Cosmic Queries shows. So what's next for 2019? Or more aptly, the next few months? Give this a quick listen and find out why dontcha? 

Such a full day of topics.First off, IRA PASTOR with BIOQUARK will discuss innovative approaches to regenerating chronic degenerative diseases and the hope for our future. Then OMAGAZINE Insiders JOSHUA PEREZ, & EILEEN FRUITHANDLER will chat about their upcoming events with me and an Omagazine fan Katherine Batey who has been a radio host for years, will chat with us... join us for insights & chats.  

Ira S. Pastor is the CEO of Bioquark, a life sciences company, developing proprietary combinatorial biologics for the regeneration and repair of human organs and tissues. Ira has over 30 years of pharmaceutical experience. He serves as a board member at multiple companies and organizations including RengerAge, the Reanima Project, The World Academy of Medical Science and the World Economic Forum’s Human Enhancement.This Episode We Discuss…Regeneration and repair of human organs and tissuesNatural regenerative capability of humansEffect of agePotential role of telomeraseBioquark’s area of focus in regenerationConditions that could potentially benefit from regeneration researchGenetics role in regenerationResearch on animals regenerative abilitiesGrowing organs outside the human body and its impact on the organ donor systemSomatic reversion and how it differs from other gene therapiesLearn more on Bioquark’s website and stay updated by following them on Facebook.Stay tuned for the next new episode of DNA Today on September 7th, 2018. New episodes are released on the first and third Fridays of the month. See what else I am up to on Twitter, Instagram, Facebook and iTunes. Questions/inquiries can be sent to info@DNApodcast.com.

The Bioquark CEO provides an informative analysis of the study of biologic solutions to human health in the 21st century. Bioquark, Inc. is a life sciences company that develops proprietary, combinatorial biologic products for health issues, including the repair and regeneration of organs and tissues, as well as for reversion of degenerative diseases. Pastor's company looks to organisms in the natural world for clues to human diseases and conditions. Pastor's team is particularly interested in the complex regeneration process of the salamander, and select worms that can amazingly revert cancerous cells back to normal tissue.  Bioquark's mission is to find the connection point that will bring these complex health processes in line with the study of human health, for advances that could help fight disease or perhaps eradicate it. The life sciences company seeks to take bold steps forward in the areas of neurology (for central nervous system damage, Alzheimer's, traumatic brain injury, spinal cord issues, etc.), cancer, and metabolic disorders (diabetes, and others). Pastor will provide an overview of their study of localized cells and why it's important to figure out the signaling and regenerative processes these cells use to grow new cells that are regionally specific. And he'll explain how Bioquark's work is furthering the historical study of the human egg, as the egg contains all the signals necessary to start its journey to become a human embryo. Ultimately, Pastor hopes to find ways to bridge the gap between what we know about organisms and their ability to regenerate tissue, and wound healing in humans. Finding the answers that lie within that gap may hold the key to startling advances in human health.

Join the power-hour of enlightenment on Aging GreatFULLy for this insightful and thought-provoking conversation with guest Bioquark Inc.- Induced Endogenous Regeneration And Repair CEO Ira Pastor who shares in this enlivening dialogue you are sure to enjoy! Don't miss "Longevity, Science and Unexplained Phenomenon!" From disease reversion to after death communication, cryogenic freezing and scientific innovation, spinal chord breakthroughs, regeneration, gain in function and terminal lucidity, this is an interesting conversation from beginning to end covering topics that rarely get the spotlight -- but one's that will certainly peak your interest and curiosity. Pastor shares what we can learn from nature and how we can use this knowledge in the medical and science community for our own health, innovation and disease reversal. Join Host Holley Kelley / Latter-Life Planning Institute and guest Ira Pastor, CEO or Bioquark, Inc.for this not-so-ordinary conversation and what the future may hold for us as far as our longevity, including the possibility of escaping or delaying death itself! It's all on the CTR Network at 11amPT and if you miss the live show you can always subscribe and NEVER miss a show on any podcast venue of your choice!

Bioquark, Inc. is a life sciences company that develops proprietary combinatorial biologic products for both the regeneration and repair of human organs and tissues, as well as the reversion of a range of chronic degenerative diseases. We talk about integrating and compiling information to create possibilities. We also talk about listening to the market and how to look at the power of mother nature to find clues to how things work. Golden nuggets: Be prepared for the long haul Have the guts to tinker Be prepared for a paradigm shift Keys to success: Don’t be afraid to admit that you don’t know Build the right team Actionable tip: Remove, eliminate yourself from vampire that bring negative energy to what you are trying to achieve. Inspiration: "If you accept a limiting belief, then it will become a truth for you." Louise Hay Resources: Ira Pastor – Bioquark Inc. http://www.bioquark.com 3 Ps of EmPowerment Sign up for the Enterprise NOW! mailing list and get a free download of the 3 Ps of EmPowerment worksheet. Or send me an email at eflenard@enterprise-now.biz.

Many other organisms have superhuman abilities, such as the capacity to ward off cancer, periodically reverse aging, regenerate limbs, and even regrow brains. Yet these non-human species share many genetic similarities with us. This naturally raises the question of whether we can learn from other animals in our quest to delay aging, reverse disease, and – dare I say it – return to life from the empty expanse of death. These lofty goals bring us to today's episode of humanOS radio in which Dan speaks with Ira Pastor, CEO of Bioquark.

Biological Time Travel: Organ Regeneration & Brain Reanimation – Turning back time in cells and tissues with the new medical techniques of bio-logics, simulating “t = 1” in the human body...This week’s guest is Ira Pastor, CEO of the revolutionary biomedical firm BioQuark in Philadelphia. I had no idea who these people were until Ira messaged me about appearing on the show…and I’m so glad he did, because otherwise I don’t k now when I would have learned about their work with new techniques that enable truly miraculous treatment of brain trauma, catastrophic organ failure, and other complex and confounding issues. We’re on the cusp of another moment in history when we have to redefine what it means to be “dead,” and how far someone can go before they’re irrecoverable. And at the prow of that epochal shift is BioQuark’s method of simulating ooplasm – in other words, “tricking” our cells into thinking that they’re fertilized ova at the very beginning of embryonic development, so they’ll do amazing feats that even stem cells won’t do.I have to admit, I went into this conversation a skeptic. And everything is still bracketed by a big “IF” – but I’m considerably more willing to believe that this is coming, soon, and that it’s going to be a good thing. Get ready to have your mind blown by a conversation about the miracles that might be commonplace in just a few more years…http://bioquark.comSubscribe on Apple Podcasts • Stitcher • Spotify • iHeart RadioJoin our Facebook Discussion GroupWe Discuss:• Why do some other organisms (like jellyfish and amphibians) demonstrate such awesome regenerative abilities, but human beings don’t?• How to reset a cell’s internal “clock” to zero and induce extraordinary regenerative abilities;• How this research builds on existing science dating back to the 1950s (and retrieves “lost knowledge” from other animals we’ve been evolutionarily separated from for hundreds of millions of years);• How biology as a lab science has changed over the last century, and how that (in part) reflects changing sentiments about the relationship between masculine and feminine, physics and biology, waves and particles;• Neuro-regeneration and neuro-reanimation research and the link to The Immaculate Conception and our lineage’s trend toward increasing neoteny and pedomorphism;• Regarding Liz Parrish, Aubrey DeGrey, and other death-resisting transhumanists…where does work like Bioquark’s fit into the picture of radical life extension and its current genomic/pharmaceutical bias?• What’s the worst that could happen? Is this going to be affordable for everyone? Ira addresses issues of unequal access and (“access for everybody, it’s not just for the billionaires”) and puts Michael at ease about other possible negative outcomes. (Including ZOMBIES.)• The Future of the Medical Industry: a decrease in pharmaceutical company dominance and the business of endless management, and the rise of a business of CURES – no lifelong dependence on medication, no 3D printed transplant organs, just good old-fashioned “miraculous” healing, along with electroceuticals, microbiome supplements, parasite-based treatments, • The Future of Medical Research: international alliances, Right To Try, navigating a complex menu of potential regulatory environments for research, and how Merck partnered with China to create a tropical island hub for medical research tourism…• And more! See acast.com/privacy for privacy and opt-out information.

We are going to take a little different turn this week and perhaps take a look into the future a little bit.   We glad to have with us, Ira Pastor, Chief Executive Officer – Bioquark Inc.    Ira has over 30 years of experience across multiple sectors of the pharmaceutical industry.  Currently, he is also a Board Member of RegenerAge  a clinical company focused on expedited translational therapeutic applications of regenerative and rejuvenative healthcare interventions, the Reanima Project (http://www.reanima.tech), and member of the World Economic Forum's Human Enhancement council.    Ira's company is applying a technology called combinatory biologics to essentially regrow tissue! check this show out....   Learn more about Ira and his work at BioQuark here

Ira Pastor, CEO of Bioquark, superhero geek   Bioquark: Bioquark is a regenerative healthcare company focused on developing proprietary natural biopharmaceuticals and consumer healthcare products, targeting the regeneration and repair of complex human organs and tissues. Ira Pastor, CEO of Bioquark, is also a 30+ year veteran of the traditional pharmaceutical industry. He left pharmaceuticals to start Bioquark due to the fact that, in spite of generating close to $1 trillion annually,  his former industry was incapable of generating any cures for the chronic diseases responsible for the majority of human degeneration, suffering, and death. Bioquark is dedicated to finding a way to repair and renew our cells rather than managing our symptoms. Weekly Challenge: This week's challenge is to switch up your routines! Before you get oppositional, hear this out. I'm not talking about switching up your bedtime routine or switching up your beloved morning routine. I'm talking about eating different foods, giving your cells a breather from certain supplements, changing up some skin care ingredients,  and maybe hiking instead of doing yoga. I'm pretty bad at this, my friends. It's a hard one for me—I love what I love and I stick to what I love. My integrative medicine doctor in NY stressed this randomness idea to me once and I panicked, "But I don't want to go any day, ever, without matcha or avocados." So, I understand the panic, but he told me that if I didn't start switching it up, my body would become sensitive to the foods I love. I try to make it like a fun game now. I'm on a hunt for more NEW constantly. I urge you to look at the ruts you're in, switch it up, and see how it feels. Follow me on IG  @sheajackie for updates (and remember the updates are usually in my stories). Discussed in this Episode: What is degenerative disease Other species that naturally regenerate like the salamander How other species deal with cancer by turning their cells back into normal, healthy tissue How Bioquark is working to find a real solution to degenerative disease Why Ira left the pharmaceutical industry Some insights from a person who worked in pharma How prescribed drugs usually only manage symptoms What Ira thinks of antibiotics Central nervous system Peptides Living cadaver studies The power of randomness Natural at-home remedies for all sorts of conditions Wim Hoff Natural skincare Inversions and gravity Resources/ Links Listed in this Episode: Bioquark Wim Hof Want to support this podcast? Follow me on IG : @sheajackie Join the Healing Out Loud Facebook group  Follow me at toosickandnaked.com for more Subscribe/ rate/ review on iTunes Share with your friends Happy listening, dear ones

Hi and welcome to another episode of the Theatre of U, a show all about celebrating people who are rocking their UQ (Unique Intelligence). Today I am excited to introduce you to Ira Pastor.  Ira has been in the pharmaceutical industry for 30 years and is the CEO of Bioquark.  In this show Ira shares how is childhood passion for comic books and Superheros, combined with a healthy respect for the natural world, lead him into the business of trying to raise people from the dead. To learn more about this sci-fi like area of research and work, visit: http://www.bioquark.com/ On today's show Ira draws cards # 11, 17, 23, 31, 47 from the Cards for Uniqueness, Against the Ordinary. If you want more info about the podcast, our work or are interested in being featured as a guest then email my team at support@uqpower.com.au and let them know you'd like your turn in the spotlight. Thanks for tuning in, until next time remember all you have to do is #startwithU

 Regenerative Biology - Cellular Combinatorial BiologicsIra Pastor - CEO – http://www.bioquark.com (Bioquark Inc). The biologic regulatory states of our cells, tissues, and organs represent the central control processes behind our health (as well as our unfortunate transition towards disease, degeneration, and aging). His work at Bioquark focuses on these critical biomedical issues. Merging 21st-century knowledge of regenerative biology, evolutionary genomics, and bio-cybernetics, Bioquark's core program focuses on developing a novel class of substances termed combinatorial biologics, which take a unique approach to reversing underlying disease, degeneration or aging processes, as opposed to only affecting the symptoms of such conditions. His Brief Bio: "Over 30 years of experience across multiple sectors of the pharmaceutical industry including pharmaceutical commercialization, biotech drug development, managed care, distribution, OTC, and retail; Served as VP, Business Development for drug development company Phytomedics Inc., raising $40 million of private equity, consummating over $50 million of licensing deals, and bringing lead drug candidate from discovery stage to Phase III development; Prior to that, employed by SmithKline Beecham Pharmaceuticals working in sales, marketing, and business strategy positions." * Photo:Marco-Secchi-549646-unsplash His Perspective & Background"We currently live on a planet with other organisms that from a health and wellness perspective, are much further advanced than human beings. Many lower organisms can replace lost or damaged organs and tissues that are identical in structure and function to the original, effortlessly regenerating a wide variety of living tissues, including spinal cords, limbs, hearts, eyes, and even parts of their brains. Similarly, many of these same species possess fascinating skills for repairing and reversing the cellular and genetic damage. Cancer, as an example, is found to be extremely rare in species displaying an efficient regenerative mechanism, even under the action of potent carcinogens. In many cases, when cancer does occur, tumors have been found to remodel and integrate into their surroundings spontaneously, as healthy tissue. Some of these organisms can age, and then return to a youthful state later on in life. Some can even die and be reborn." Join us the hear about the varieties of http://corebrainjournal.com/testing (compelling searches for new healing options). Referenced Detailshttp://onlinelibrary.wiley.com/doi/10.1111/j.1440-169X.2007.00914.x/pdf (http://onlinelibrary.wiley.com/doi/10.1111/j.1440-169X.2007.00914.x/pdf) http://onlinelibrary.wiley.com/doi/10.1002/dneu.20918/pdf (http://onlinelibrary.wiley.com/doi/10.1002/dneu.20918/pdf) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706275/ (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706275/) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC433040/ (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC433040/) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC335936/ (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC335936/) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1735296/pdf/v040p00721.pdf (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1735296/pdf/v040p00721.pdf) http://jcb.rupress.org/content/200/6/689.full (http://jcb.rupress.org/content/200/6/689.full) http://precedings.nature.com/documents/6045/version/1/files/npre20116045-1.pdf (http://precedings.nature.com/documents/6045/version/1/files/npre20116045-1.pdf) http://jcb.rupress.org/content/115/6/1479.long (http://jcb.rupress.org/content/115/6/1479.long) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113692/pdf/jc1012518.pdf (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113692/pdf/jc1012518.pdf) http://jcs.biologists.org/content/95/3/383.full.pdf (http://jcs.biologists.org/content/95/3/383.full.pdf) -----------Pastor's Connectionshttp://bioquark.com (bioquark.com) --------------- Forward This Audio Message Link To

 Our guest Ira Pastor is CEO of Bioquark Inc. He has over 30 years of experience across multiple sectors of the pharmaceutical industry including pharmaceutical commercialization, biotech drug development, managed care, distribution, OTC, and retail.  According to Ira, "Whether we are talking about the 100,000 people who die daily from age-related ailments or the 50,000 that die from acute traumas, it is well within the intellectual capacity of humans to solve these problems of disease, degeneration, and death.   But we must truly think “outside the box”, and not fall into the traps set by the traditional pharmaceutical industry, its regulators, and the century-old model of drug development which has truly run into a brick wall.   There is a reason that microbes, and plants, and invertebrates, and amphibians, have survived for many hundreds of millions of years on this planet, and developed their own unique answers to many of the problems that plague humanity.   Nature has shown us the way; we must now follow her lead". In this interview: The truth about the pharmaceutical industryAge-reversal Death reversalDisease reversion/cancer Why are there no cures for any diseases?Is the pharma industry suppressing cures?Why it's so hard for patients dying of incurable diseases to get into compassionate use programs?  What are some solutions to this? Contact: Ira Pastor - www.bioquark.com Tamara Westwood - www.beyondhypnosis.org

Listen in to my conversation with Ira Pastor, the CEO of Bioquark, a company that is examining the regrowing abilities of reptiles and other biological creatures. Originally working in Big Pharma, Pastor talks about how they are hoping to isolate these genes and potentially figure out how these animals regrow their spinal cord. A fascinating conversation, it is definitely worth a listen!

Join the partial crew as they interview Ira Pastor, the CEO of a biotech company called BIOQUARK to talk about biomimicry. The incredible progress of these companies pushing the envelope when it comes to biology melding with technology. It offers a bright picture of the future in a time where doom and gloom are much more popular. Come and listen with hopeful glee at the bright future they are working on Nancy gives us the top 10 most liveable cities and we find out that in Utah, they'd rather pray for snow than fight climate change

Ira Pastor is the CEO of Bioquark, Inc., which is a biotechnology company working in the field of lengthening human life and even regenerating bodies that are technically dead. He and Roberta have been friends for years, and at last she has invited him to do on Seek Reality the kind of enjoyable battling they […]

Dr. Jeanette welcomes Ira Pastor, is the CEO of Bioquark , a company which focuses on regenerative biology, evolutionary medicine and comparative genomics.  He is also a wellness advocate in multiple corporate positions to change the way we can help our body with products and devices. How does our body work?  How does it regenerate and break down?  Are we in control of keeping it in perfect form no matter what decade we are in of life? Are we evolving so rapidly that perhaps our physical body just can't keep up?  Do we really want to keep a body around that is failing and spend all our life and time to try and repair it?  Is the body the most effective organism in this universe? How have we become inefficient at maintaining perfect health and potentially created our own physical demise? Can we change it, get out of it, and create a world that is evolved to a higher existence and honor all who are participating in holding the earth and evolution. Can our body regenerate? Can we create organs and tissues to support a healthy body when we are hit with a huge insult to our physical being?  For more information visit: www.BioQuark.com and www.facebook.com/Ira.Pastor.7 For health and wellness support with Dr. Jeanette visit:  www.MyPersonalAdvocate2.com  

Ira Pastor is the CEO of BioQuark, a biotechnology company that develops proprietary combinatorial biologics for the regeneration and repair of human organs and tissues. Ira has raised over $40 million of private equity for various pharmaceutical companies and has worked in sales, marketing, and business strategy positions. BioQuark is a brand that actively uses […]

What if you could live forever? What if when you died, you could be brought back to life? Or, if cancer could simply be reversed or changed? And what if spinal cord injuries could be self-healed? Today’s Aging GreatFULLy show is a deep dive into the exploration of biological science and incredible discoveries on the brink of unfolding with guest, Ira Pastor, CEO of Bioquark, Inc.. Bioquark focuses on three R’s Regeneration, Reversion and Rejuvenation. By looking to back to nature, Bioquark is uncovering and exploring complex forms of regenerative biology to create novel therapeutics for human regeneration and disease reversion. We will be talking everything from terminal lucidity, how the mind can experience a gain in function and know things it never learned and even explore the many fascinating studies documented in literature on reincarnation and instances where children recite perfect recollections of another previous life. Have you experienced an after-death communication? We will take a deeper dive into some of the more unexplainable topics related to the human mind and experiences of the consciousness and memory and even have a conversation about brain death, including reversal. This is a show that is full of interesting and unexplained phenomenon, both scientifically and beyond. And speaking of beyond, have you considered cryogenic freezing as an option post death? From exploring the Central Nervous System rejuvenation to a salamanders’ ability to repair itself, we will deliver a power-hour of enlightenment sure to entertain and provoke thought for every listener! One thing is certain, this Aging GreatFULLy will peak your curiousity, expand the depths of your thinking and glean inspirational and entertaining possibilities for the future of science, disease, living, aging and even death itself. To learn more about Ira Pastor and Bioquark, visit www.bioquark.com.

The science of reawakening the dead using a variety of extensive studies connecting regeneration and repair mechanisms of non-human species to humans. Some lower organisms can age, and then return to a youthful state later on in life. Some can even die and be reborn. Unfortunately for humans, the situation is very different. Bioquark's mission is to develop novel biologics to re-ignite these capabilities for a variety of therapeutic applications in humans.

Anti-aging expert, biogenetic thought leader, and overall super human Ira Pastor is back to regale us with more tips on living forever. Stay a little while as we chat health advancements, biology and technology, then stay even longer on good ole’ planet earth equipped with your newfound immortal knowledge. In 2243 you’ll thank us. You’re welcome in advance. Bio and Related Articles for Ira Pastor http://www.bioquark.com/ https://www.weforum.org/people/ira-pastor http://health.usnews.com/health-care/patient-advice/articles/2017-06-29/how-could-synthetic-biology-help-people-with-diabetes http://www.worth.com/25-ways-to-live-longer/

  Interview starts 33:25 Ira Pastor joins us to chat about Bioquark, the technology and research into regenerative cell therapy and new substances called combinatorial biologics.  The focus is on fixing the problems at the cellular level as apposed to masking the symptoms. Ira has been in the pharmaceutical industry for 30 plus years. We chat about his interest in Sci fi and comic books as well as tapping into living organisms to study how they regenerate. They are starting with 3 targets…. the kidneys, oncology, and the essential nervous system.   We also chat about how many species are way ahead of humans in these terms, combating the modern lifestyle, micro rna, synthetic biology, electroceuticals, stem cells, various research and biomedical literature, the difference between cultures and countries accepting this type of work, FDA research, and of course much more.   http://www.bioquark.com/    In the intro we talk about ways to support the show, Graham reads the UFO quote from Darren’s favorite website. They share some listener feedback through emails and social media. See the links below for stuff we chatted about during the show and the intro:   https://www.cia.gov/library/readingroom/docs/CIA-RDP96-00792R000400370004-0.pdf    http://www.abovetopsecret.com/forum/thread500711/pg1    http://www.grimerica.ca/episodes/139/ Rick Simpson Ep.   https://ase.tufts.edu/biology/faculty/levin/    https://www.biosafety.be/sites/default/files/120911_doc_synbio_sbb_final.pdf    Please help support the show…. Grimerica’s DoBeDoBeDo List: Grimerica is fully and solely listener supported. We adhere to the Value for Value model.  0 ads, 0 sponsorships, 0 breaks, 0 portals and links to corporate websites… just many hours of unlimited content for free. Thanks for listening!!   Join the chat / hangout with a bunch of fellow Grimerican’s  www.grimerica.ca/chats   Support the show directly http://www.grimerica.ca/support https://www.patreon.com/grimerica     Leave a Voicemail http://speakpipe.com/grimerica Leave a review on iTunes and/or Stitcher https://itunes.apple.com/ca/podcast/the-grimerica-show/id653314424?mt=2# http://www.stitcher.com/podcast/the-grimerica-show    Sign up for our newsletter http://www.grimerica.ca/news Leave a comment, ideas and guest/topic suggestions under any episode or blog http://www.grimerica.ca/   SPAM Graham = and send him your synchronicities, feedback, strange experiences and psychedelic trip reports!! graham@grimerica.com InstaGRAM  https://www.instagram.com/the_grimerica_show_podcast/    Tweet Darren https://twitter.com/Grimerica   Connect through other platforms: https://www.reddit.com/r/grimerica/  https://gab.ai/Grimerica    Purchase swag, with partial proceeds donated to the show www.grimerica.ca/swag Send us a postcard or letter http://www.grimerica.ca/contact/ Thanks to Wayne Darnell for help with the website. http://www.darnelldigitalink.com/ http://www.lostbreadcomic.com/ link to Napolean Duheme's site  Felix’s Site sirfelix.bandcamp.com   Christmas Carol Video   MUSIC Grimerica Theme - Lock & Key   Warm Up Suit - Broke for Free The Power of You Diamond Mind - Sir Felix Ortega II

patreon.com/grognostics - donate to the show audible.com/grog - start free audible trial today For a human living in 5,000 B.C. living to the ripe age of 60 may have felt like immortality. Today most expect to live into their 80’s. What happens in 2150? 2750? Will life extension continue? Could we someday, supported by humanity’s greatest advancements in biology, computers, and medicine become immortal? On today’s show we’re joined by renowned, biogenetic expert Ira Pastor, CEO of the Philadelphia-based life sciences company, Bioquark Inc. His company takes a unique approach to age reversal, merging knowledge from various disciplines in regenerative biology, evolutionary genomics, and bio-cybernetics to directly aid in regeneration and repair of the body. We’re searching for the fountain of youth. Why don’t you join us and stay a while - like for 60 minutes? Heck, join us eternally… Amie also guests, Oisin reviews a Trappist beer, and even Russ, the neighbor stops by for a pint. Bio and Related Articles for Ira Pastor http://www.bioquark.com/ https://www.weforum.org/people/ira-pastor http://health.usnews.com/health-care/patient-advice/articles/2017-06-29/how-could-synthetic-biology-help-people-with-diabetes http://www.worth.com/25-ways-to-live-longer/

In this episode, our guest is Ira Pastor. He is the CEO of Bioquark, a life sciences company developing propietary biologic products for the repair and regeneration of tissues. Ira is on a mission to help people live longer, so they can reach their finish line. This episode, we will learn about his inspiration, influences, success, and vision. --- Support this podcast: https://anchor.fm/reachingthefinishline/support

Ira has over 30 years of experience across multiple sectors of the pharmaceutical industry including pharmaceutical commercialisation, biotech drug development, managed care, distribution, OTC, and retail; Served as VP, Business Development for drug development company Phytomedics Inc., raising $40 million of private equity, consummating over $50 million of licensing deals, and bringing lead drug candidate from discovery stage to Phase III development.Prior to that, employed by SmithKline Beecham Pharmaceuticals working in sales, marketing, and business strategy positions. Ira has also served as Vice President of Corporate Development for the pharmacy benefit management company Prescription Delivery Systems (acquired by Cigna Health Insurance); He has an MBA, Temple University and a BS, Pharmacy, Rutgers University. He is also a Board Member of RegenerAge SAPI de CV, (www.regenerage.clinic/en/) a clinical company focused on expedited translational therapeutic applications of regenerative and rejuvenative healthcare interventions, the Reanima Project (http://www.reanima.tech), member of the Executive Council of the World Academy of Medical Science – WAMS (https://wams.online/our_team/ira-s-pastor/), and member of the World Economic Forum's Human Enhancement council (https://www.weforum.org/people/ira-pastor).He runs Bioquark, which is focused on the development and commercialisation of a novel range of biologic based products and services that have the ability to alter the biological regulatory state of human tissues and organs, with the goal of curing a wide range of diseases.Web: http://bioquark.com LinkedIn: https://www.linkedin.com/in/iraspastorTwitter: https://twitter.com/irat1onal Facebook company page: https://www.facebook.com/Bioquark Facebook profile: https://www.facebook.com/ira.pastor.7

Ira Pastor talks about Bioquark's work reviving the brain dead, human regeneration, diseases, anti-aging and more. Psychic Tristan Rimbaud reveals his 2018 predictions and looks back at 2017.http://parabnormalradio.com/2018/01/20/ep-237-ira-pastor-tristan-rimbaud/

Ira Pastor e: pastor@bioquark.com w: bioquark.com Skype: iraspastor FB: ira.pastor.7 T: ira1onalIra is CEO of Bioquark Inc. which explores complex forms of regenerative biology in nature to create novel therapeutics for human regeneration. He speaks to brain regeneration work and creating “combinatorial” interventions in the era of the “single magic bullet” drug philosophies. He also talks about Bioquark’s history and philosophy.

Ira Pastor is CEO of Bioquark, a Biotechnology company working on reviving dead brains and repair organ tissue using natural sources. Bioquark, Inc. is focused on the development and commercialization of a novel range of biologic-based products and services that have the ability to alter the biological regulatory state of human tissues and organs, with the goal of curing a wide range of diseases.The biologic regulatory states of our cells, tissues, and organs represent the central control processes behind our health (as well as our unfortunate transition towards disease, degeneration and aging), and a technology/product platform that can reverse negative transitions, will be transformational in the pharmaceutical industry, as well as in the wider healthcare business segment.The company's core program focuses on developing a novel class of substances termed combinatorial biologics, which take a unique approach to reversing underlying disease, degeneration or aging processes, as opposed to affecting the symptoms of such conditions, as most marketed pharmaceutical products currently do today.Combinatorial biologics, which work at the level of the regulatory genome, and are modeled off of biochemical dynamics found in various species which can naturally modify biologic regulatory state to achieve beneficial endpoints such as complex tissue and organ regeneration, disease reversion, and even biological age reversal.If you would like more information on Ira please check out the following links below:Ira's LinkedIn - https://www.linkedin.com/in/iraspastor/Ira's Twitter - https://twitter.com/IraSamuelPastorBioquark - http://www.bioquark.com/Humans 2.0 Twitter - https://twitter.com/Humans2PodcastTwitter - https://twitter.com/markymetryMedium - https://medium.com/@markymetryFacebook - https://www.facebook.com/mark.metry.9Instagram - https://www.instagram.com/markmetry/Mark Metry - https://www.markmetry.com/

Ira Pastor is CEO of Bioquark, a Biotechnology company working on reviving dead brains and repair organ tissue using natural sources. Bioquark, Inc. is focused on the development and commercialization of a novel range of biologic-based products and services that have the ability to alter the biological regulatory state of human tissues and organs, with the goal of curing a wide range of diseases.The biologic regulatory states of our cells, tissues, and organs represent the central control processes behind our health (as well as our unfortunate transition towards disease, degeneration and aging), and a technology/product platform that can reverse negative transitions, will be transformational in the pharmaceutical industry, as well as in the wider healthcare business segment.The company’s core program focuses on developing a novel class of substances termed combinatorial biologics, which take a unique approach to reversing underlying disease, degeneration or aging processes, as opposed to affecting the symptoms of such conditions, as most marketed pharmaceutical products currently do today.Combinatorial biologics, which work at the level of the regulatory genome, and are modeled off of biochemical dynamics found in various species which can naturally modify biologic regulatory state to achieve beneficial endpoints such as complex tissue and organ regeneration, disease reversion, and even biological age reversal.If you would like more information on Ira please check out the following links below:Ira's LinkedIn - https://www.linkedin.com/in/iraspastor/Ira's Twitter - https://twitter.com/IraSamuelPastorBioquark - http://www.bioquark.com/Humans 2.0 Twitter - https://twitter.com/Humans2PodcastTwitter - https://twitter.com/markymetryMedium - https://medium.com/@markymetryFacebook - https://www.facebook.com/mark.metry.9Instagram - https://www.instagram.com/markmetry/Mark Metry - https://www.markmetry.com/

Bioquark Inc. & Tissue Regeneration with Ira S. Pastor Bioquark Inc. is focused on the development of novel biologics that have the ability to naturally modify the regulatory state of human tissues and organs, with the goal of curing a range of chronic degenerative diseases, as well as effecting complex regeneration. The biologic regulatory states of our cells, tissues, and organs represent the central control processes behind our health (as well as our unfortunate transition towards disease, degeneration, and aging). Merging 21st-century knowledge of regenerative biology, evolutionary genomics, and bio-cybernetics, Bioquark’s core program focuses on developing a novel class of substances termed combinatorial biologics, which take a unique approach to reversing underlying disease, degeneration or aging processes, as opposed to only affecting the symptoms of such conditions. Ira Pastor, Chief Executive Officer More than 30 years of experience across multiple sectors of the pharmaceutical industry including pharmaceutical commercialization, biotech drug development, managed care, distribution, OTC, and retail; Served as VP, Business Development for drug development company Phytomedics Inc., raising $40 million of private equity, consummating over $50 million of licensing deals, and bringing lead drug candidate from discovery stage to Phase III development. For more information visit: http://www.bioquark.com/ ************************************************* For more information about BITEradio products and services visit: http://www.biteradio.me/index.htm

When it comes to age reversal and complex regeneration in humans, a basin of research has been put in front of us. How much do we know about the brain, consciousness, and death reversal? As Big Pharma makes a trillion dollars annually, are they interested in finding cures? What valuable lessons are we learning from evolution? On this episode, we have an in-depth conversation about exciting developments in biology with Bioquark CEO, Ira Pastor. The symptoms of a disease are nothing more than late-appearing indications that something is wrong. They have nothing to do with the biological factors that come beforehand. -Ira Pastor Three Takeaways Disease is an emergent property that is multifactorial. Evolution has created many answers for the problems out there. Complex regeneration takes place when you get both the structure and function back. At the start of the show, Ira talked about his background and shared on how the pharmaceutical industry deals with disease. Next, we talked about complex regeneration and the animals that are able to do it. Ira also talked about how to slow down the aging process by looking to nature for the answers. Towards the end, he shared on why he’s excited about the future of biology. We also discussed: The importance of getting back to nature Brain regeneration and death reversal Technology and the transformational window There’s a lot to be excited about in the fields of age reversal and curing chronic degenerative disease. Human beings could have a beautiful future thanks to advances in science and technology. There are endless possibilities when merging biology and physics. It’s critical for us to study death from a therapeutic angle and study the evolutionary reasons behind medicine and biology. Ultimately, this is how we will make strides in complex tissue regeneration, reversal of diseases, and reversal of aging. Guest Bio Ira is the CEO of Bioquark. He has over 30 years of experience across multiple sectors of the pharmaceutical industry including pharmaceutical commercialization, biotech drug development, managed care, distribution, OTC, and retail. Go to www.bioquark.com to learn more.

Greetings, SuperFriends! Today we are joined by Ira Pastor. He is the CEO of BioQuark, and he has over 30 years of experience across multiple sectors in the pharmaceutical industry, working on biological solutions, managed care, OTC's, and more. He's served as the V.P. of business development for a drug development company. He's raised tons of money for different companies, and today he's working, as I said, at BioQuark, which is a company doing really really interesting things with biologic solutions to many of our health problems. I wanted to talk to Ira to understand what research is being done today to make us literally superhuman: to help us live forever, get rid of diseases, and so on. I learned a lot about just the types of research that are being done, and ultimately, I found it super interesting just the reverence and respect that Ira has for Mother Nature as an innovator and as a way for developing solutions to problems. It's a great episode. I'm sure you guys are going to enjoy it very very much!  

What if your body came with a reset button which could erase cellular damage, stimulate regeneration and cure a wide range of diseases? My guest today, Ira Pastor from Bioquark is developing consumer healthcare products targeting the regeneration and repair of complex human organs and tissues. Listen in and learn how Ira Pastor and Bioquark is creating Healing Ties all around us!

What if your body came with a reset button which could erase cellular damage, stimulate regeneration and cure a wide range of diseases? My guest today, Ira Pastor from Bioquark is developing consumer healthcare products targeting the regeneration and repair of complex human organs and tissues. Listen in and learn how Ira Pastor and Bioquark is creating Healing Ties all around us!

What if your body came with a reset button which could erase cellular damage, stimulate regeneration and cure a wide range of diseases? My guest today, Ira Pastor from Bioquark is developing consumer healthcare products targeting the regeneration and repair of complex human organs and tissues. Listen in and learn how Ira Pastor and Bioquark is creating Healing Ties all around us!

What if your body came with a reset button which could erase cellular damage, stimulate regeneration and cure a wide range of diseases? My guest today, Ira Pastor from Bioquark is developing consumer healthcare products targeting the regeneration and repair of complex human organs and tissues. Listen in and learn how Ira Pastor and Bioquark is creating Healing Ties all around us!