Type of T cell that regulates immune responses
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There's been a lot of talk about allergy symptoms becoming more severe over the last few years. What is contributing to this change? And more importantly, what can we do to control our environments and help support our bodies' immune systems? Our guest today is double-board certified physician and allergist, Dr. Tania Elliot. She's joining us for an insightful conversation on allergies and immunology. You're going to learn what allergies are and how they develop, why there's an explosion of allergies happening right now, and what the main root cause is. Dr. Elliot is going to unpack how to reduce allergy exposures and how your immune system works when allergens are present. You're also going to learn practical tips for optimizing your environment, including air quality, sleep practices, and how to travel as healthily as possible. Dr. Tania Elliot is a leading authority in this subject matter, and I know you're going to love this episode of The Model Health Show. Enjoy! In this episode you'll discover: What Dr. Elliot's driving force for becoming a doctor was. (7:45) Why working in allergy and immunology is like being a detective. (9:57) What an allergy actually is. (11:59) The connection between allergies, autoimmunity, and inflammation. (12:27) Three main reasons why allergies are more prevalent today. (12:46) The interesting role of Th2 cells. (14:39) How c-section deliveries impact the baby's immune system. (16:25) Why peanut allergies have become more common. (18:34) What a histamine reaction is. (22:10) The difference between Th1 cells and Th2 cells. (22:18) What super pollen is. (24:32) How our indoor microbiome can influence allergies. (25:18) The 3 main things Dr. Elliot would never order in a restaurant. (29:24) What to avoid if you struggle with indoor allergies. (34:03) Why you should never let your pets on your bed. (36:20) What to avoid in a hotel room for better health. (38:33) The best sleep-supportive supplements. (43:49) How the humidity level in your bedroom affects allergies. (45:03) What the first line of treatment against allergies is. (46:45) Which foods have the highest histamine levels. (50:34) Items mentioned in this episode include: Foursigmatic.com/model - Get an exclusive discount on your daily health elixirs! Myessentia.com/model - Get a discount on organic, supportive mattresses! Healthy Home Guide - Read Dr. Tania Elliot's e-book! Connect with Dr. Tania Elliot Website / Substack / Instagram Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Spotify Soundcloud Pandora YouTube This episode of The Model Health Show is brought to you by Four Sigmatic and Essentia. Visit foursigmatic.com/model to get an exclusive discount on mushroom and adaptogen-packed blends to improve your life. Essentia makes the best performance certified non-toxic mattresses. Get a discount on any organic mattress when you use my link, myessentia.com/model.
Should you really trust the vaccine schedule? In this episode of the Awake & Winning Podcast, Kaylor sits down with Dr. Taylor Bean—a licensed naturopathic doctor, vaccine educator, and founder of VaccineOptimization.com—who's known for her nuanced, evidence-based approach to vaccine education and immune system support. With over a decade of clinical experience, Dr. Bean is on a mission to help parents make informed, empowered decisions about their health and their children's. From a Love Island dating story to a masterclass on infant immunity, this episode unpacks the real mechanisms behind vaccines, the role of aluminum, and why the current vaccine schedule doesn't align with infant physiology. If you've ever questioned mainstream medicine or felt gaslit in a doctor's office, this conversation is your permission to ask better questions and explore better answers. Episode Highlights: vaccines, aluminum in vaccines, informed consent, infant immunity, pharmaceutical risk, root cause medicine, public health, naturopathic medicine, immune development, medical coercion, childhood illness, alternative vaccine schedules Takeaways: Why aluminum is more concerning than mercury in vaccines The truth about infant immunity and TH2 dominance Why breastfeeding plays a vital role in immunity development The flaws in the vaccine schedule tied to maternal work policies How to support the immune system pre and post-vaccine Why functional medicine offers better viral care than conventional The importance of informed consent over fear-based compliance If you enjoyed the episode, please be sure to take a screenshot and share it out on Instagram and tag @thekaylorbetts. Also, please make sure to give us a review and a five star rating if you're loving what we are doing! _____________________________ RESOURCES & LINKS MENTIONED IN THIS EPISODE: Instagram | https://www.instagram.com/drtaylorbean/ Facebook | https://www.facebook.com/drtaylorbean Websites | https://drtaylorbean.com/ https://taylormadewellness.com/ https://vaccineoptimization.com/ _____________________________ SPONSORS: Truly Tallow | https://www.trulytallow.com/ Use code “SUNNYBALLS10” at checkout for 10% off your order The Wellness Company | https://www.twc.health/collections/signature/products/ultimate_spike_detox Use code “WINNING” at checkout for 10% off your order _____________________________ IMPORTANT UPDATES: Check out the Awake & Winning Website | https://awakeandwinning.com/ Join the Awake & Winning Life AW-cademy | https://theawlife.com/ Join the Awake & Winning Business AW-cademy | https://theawbiz.com Join the Awake & Winning POD-cademy | http://yourwinningpodcast.com/ Follow Kaylor on Instagram | https://www.instagram.com/thekaylorbetts/ Join Kaylor's Newsletter | https://awakeandwinning.lpages.co/optin/
In this special episode of the RWS Clinician's Corner, we have the privilege of hosting Dr. Chris Turnpaugh, a renowned figure in the field of functional medicine and the medical director of Restorative Wellness Solutions. Dr. Turnpaugh delves into the critical relationship between toxin exposure and susceptibility to infectious diseases such as Lyme and Long Covid. He shares groundbreaking insights on how the accumulation of environmental toxins can shift immune responses, potentially increasing vulnerability to infections, as well as offering strategies to support detoxification, adjust immune system balance, and improve overall resilience. Whether you're a seasoned functional health practitioner or just delving into this field, the clinical pearls Dr. Turnpaugh shares in this episode provide a vital understanding of how to tackle complex health challenges in today's increasingly toxic world. In this interview, we discuss: - Increased susceptibility to chronic infections due to environmental toxins and the influence of toxins on TH2 dominance in the immune system - Testing options and how to address complex client cases - Strategies for addressing toxic burden (e.g., detoxification, supplementation, etc.) - Prevention and maintenance strategies The Clinician's Corner is brought to you by Restorative Wellness Solutions. Follow us: https://www.instagram.com/restorativewellnesssolutions/ Connect with Dr. Chris Turnpaugh: Website: TurnpaughHWC.comFacebook: https://www.facebook.com/TurnpaughHWC/ Instagram: TurnpaughHealth Timestamps: 00:00 "Linking Toxin Burden to Infections" 05:00 Chemicals Weaken Immune Response 09:06 Decreased Resilience to Modern Stressors 12:22 Chemical Exposure in Daily Life 14:14 Exploring Tailored Detox Strategies 16:55 Challenges in Treating Fragile Patients 21:44 Hormone Health: Reducing Toxic Burden 24:55 Chronic Illness Resolutions Compared 28:00 Root-Cause Health Training Program 29:16 "Symptom Differentiation in Clinical Process" 34:44 Digital PCR for Bartonella Testing 35:29 Understanding Post-Infection Symptoms 38:42 "Fish vs. Digital PCR Testing" 42:24 Balancing Tregs and Th1/Th2 46:59 Preventive Health: Balancing the Immune System 48:26 Essential Desert Island Supplement: NAC 54:16 Understanding Patient Conditions and Treatment Priorities 56:39 "Clinician's Corner Podcast Highlights" Speaker bio: Dr. Chris Turnpaugh is a practitioner and CEO at Turnpaugh Health, a Functional Medicine wellness center, which he founded in 1999. The center, one of the largest in the country, has grown to over 20 healthcare providers and a team of more than 50 in five locations. Turnpaugh Health provides in-depth holistic care focusing on functional medicine, investigating the mechanisms of dysfunction in patients. The clinic also provides integrative family medicine, lifestyle medicine, and many complementary wellness services. Over his twenty years in practice, Dr. Turnpaugh has joined ILADS and is known as a thought leader in Lyme disease and associated co-infections. He also traveled to Lake Como to participate on the PANDAS International board. He has a deep interest and extensive knowledge in pediatric neurological disorders and methods of supporting these children holistically. Dr. Turnpaugh has lectured on a broad variety of health topics, both nationally and internationally. His application of functional medicine as it relates to the neuro/endocrine/immune systems is a unique clinical approach to non-pharmacological treatments. He is well respected among his peers and patients as a provider and functional medicine instructor. He has treated thousands of patients in his practice and mentored hundreds of practitioners. His true passion is teaching functional medicine to other practitioners and helping patients to optimize their health. Keywords: Restorative Wellness Clinicians Corner, functional health professionals, functional medicine, toxin burden, infectious diseases, chronic infections, TH1 and TH2 immune system, Lyme disease, Long Covid, autoimmune conditions, root cause medicine, total tox burden, detox pathways, environmental toxins, mold exposure, Cryptolepis, immune system balance, TH2 dominance, glutathione, NAC supplementation, environmental toxicity, reducing toxic exposure, tick bite prevention, laboratory testing, immune dysregulation, chronic illness recovery, viral infections, vitamin D, quercetin, microbiome health, detoxification Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Dr. Wayne Shreffler, Chief of Pediatric Allergy and Immunology and Co-Director of The Food Allergy Center at Massachusetts General Hospital. Dr. Shreffler is also an investigator at The Center for Immunology and Inflammatory Disease and The Food Allergy Science Initiative. His research is focused on understanding how adaptive immunity to dietary antigens is both naturally regulated and modulated by therapy in the context of food allergy. This interview covers the results of a research paper on The Intersection of Food Allergy and Eosinophilic Esophagitis, co-authored by Dr. Shreffler. Disclaimer: The information provided in this podcast is designed to support, not replace the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own. Key Takeaways: [:50] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, GSK, Sanofi, and Regeneron. Ryan introduces co-host, Holly Knotowicz. [1:15] Holly introduces today's topic, the intersection of food allergy and eosinophilic esophagitis. [1:26] Holly introduces today's guest, Dr. Wayne Shreffler, Chief of Pediatric Allergy and Immunology and Co-Director of The Food Allergy Center at Massachusetts General Hospital and an investigator at The Center for Immunology and Inflammatory Disease and The Food Allergy Science Initiative. [1:43] Dr. Shreffler's research is focused on understanding how adaptive immunity to dietary antigens is both naturally regulated and modulated by therapy in the context of food allergy. [1:54] Holly welcomes Dr. Shreffler to Real Talk. When Holly moved to Maine, she sent her patients to Dr. Shreffler at Mass General. [2:25] Dr. Shreffler trained in New York on a Ph.D. track. He was interested in parasitic diseases and the Th2 immune response. Jane Curtis, a program director at Albert Einstein College of Medicine, encouraged him to consider MD/PhD programs. He did. [3:31] Jane Curtis connected him to Hugh Sampson, who was working with others to help understand the clinical prevalence of food allergy and allergens. [3:51] As a pediatric resident, Dr. Shreffler had seen the burden of allergic disease, caring for kids in the Bronx with asthma. His interest in Th2 immunity, the clear and compelling unmet clinical need, and the problem of food allergy guided his career. [4:31] Dr. Shreffler's wife has food allergies and they were concerned for their children. Fortunately, neither of them developed food allergies. [5:21] Dr. Shreffler thinks the food allergy field has a lot of people who gravitate toward it for personal reasons. [5:53] Food allergy is an adverse response to food that is immune-mediated. There is still uncertainty about this but Dr. Shreffler believes that a large percentage of patients with EoE have some triggers that are food antigens. [6:27] The broad definition of food allergy would include things like food protein-induced enterocolitis syndrome (FPIES). [6:47] The way we use the term food allergy in the clinic, there are two forms: IgE-mediated allergies and non-IgE-mediated allergies, including EoE. [7:40] Some patients have food-triggered eczema, some have FPIES. [8:04] In 2024, Dr. Shreffler and Dr. Caitlin Burk released a paper that looked at the triggers of EoE, particularly the intersection of IgE-mediated food allergy and EoE. [8:41] Dr. Caitlin Burk joined the group as they were publishing papers on IG food allergy and EoE. It was a moment where things unexpectedly came together. [9:17] Adaptive immunity to food proteins comes from antibodies that cause milk allergy, egg allergy, peanut allergy, or multiple allergies. The IgE has specificity. [9:40] T cells also are specific to proteins. They express a host of receptors that recognize almost anything the immune system might encounter. They have a long memory like B-cells. [10:09] The overlap in these two threads of research was regarding a population of T cells that are important for mediating chronic inflammation at epithelial sites, including the gut. [10:36] These T cells have been described in the airways in asthma, in the skin in eczema, and the GI tract. Researchers years ago had also described them as being associated with IgE food allergy. People with IgE food allergies avoid allergens. [11:13] T cells, being associated with chronic allergic inflammation, now being associated with food allergies which are not having chronic exposures to the allergen, was interesting and surprising. [11:30] Dr. Shreffler and his group found the T cell subset in patients who don't do well with Oral Immunotherapy (OIT) and patients who have EoE with immediate symptoms. [12:01] Dr. Shreffler notes differences. There are immediate symptoms of IgE food allergy. There is a subset of patients with EoE who have immediate symptoms that are not fully understood. Maybe IgE plays a role there. [12:28] There are different mechanisms for how symptoms are caused and so different ways of making a diagnosis. A food allergy with an IgE antibody can be measured through skin tests and blood tests. This can help identify which foods are the trigger. [12:57] This common T cell subset that we see in EoE and food allergy, helps to explain why IgE alone is not always a very specific marker for identifying people who will have immediate reactions when they're exposed to the food. [13:17] For patients who react at low levels, it's not just that they have more or better IgE but they also have an expansion of these T cells that are common between EoE and other chronic forms of allergy and IgE food allergy. [13:41] There's a lot to learn that might be relevant for patients about this T cell subset. [14:23] These T cells are a specific subset of the group of Th2 T cells, which are a subset of all CD4 T cells. Some CD4 T cells are important for responding to viruses and tumors. Others are important for responding to outside allergens. [15:01] In an allergy or a parasite infection, Th2 T cells are important. There is a subset of T cells that is driven by repetitive and chronic exposure to the triggering protein, antigen, or allergen. [15:47] Most antigens are proteins that trigger an immune response. An antigen that elicits an allergic response is an allergen. [16:30] A food trigger is a protein antigen that is an allergen. In IgE, food allergies, milk, and eggs are prevalent triggers early in life. For reasons not well understood, a lot of people outgrow them. In older patients, peanut and tree nut allergies are prevalent. [17:01] In EoE, milk is one of the most common dietary triggers into adulthood. Some patients with IgE allergy to milk can tolerate it if it's well cooked. Patients with EoE are less likely to be able to get away with regular and ongoing exposure to milk protein. [17:54] Milk, eggs, and nuts are common triggers in both conditions. There can also be rare food allergy triggers. That's part of the early evidence that the adaptive immune response was likely to be involved. It can be so specific for some people to rare things. [18:20] Hallmarks of something being immune-mediated are that it is reproducibly demonstrable as a trigger. It's going to be long-lived. It's going to be generally relatively small amounts. The immune system is good at detecting small exposures. [19:07] EoE is tricky because there's not that clear and easy temporal association between an offending allergen exposure for most people and their symptoms. People don't associate the symptoms with the triggers. [20:14] A history of having blood in the stools can be milk-allergen-driven and was associated with a diagnosis of EoE in those kids when they're older. [20:26] There are a lot of commonalities in the allergens but it's not always obvious clinically. [22:40] A challenge in diagnosing EoE is that providers have to be on guard against their biases. They have to give a patient good advice. In EoE there is no test to identify triggers, except rigorous introduction, elimination, reintroduction, and endoscopies. [24:18] For some of Dr, Shreffler's patients, it becomes less important to know their dietary triggers. They gravitate toward an approved form of treatment that may, if successful, allow them to have a more normal diet because of effective medication. [24:50] Dr. Shreffler thinks there are other triggers, including pollens. There is evidence of seasonality of active EoE in patients shown to have allergic sensitization to pollens. That's indirect evidence. If the body is making IgE, it's likely making other responses. [25:32] There are questions about how large the population of patients is who have EoE that may be more intrinsically than extrinsically driven because of genetic variations. [25:54] Dr. Shreffler believes that EoE in some patients is allergen-driven and in some patients EoE is food-driven. Food is a trigger for the majority of pediatric patients and a large percentage of adult patients but not necessarily the exclusive trigger. [27:04] If a patient is motivated to learn what dietary triggers may be at play, Dr. Shreffler often makes assessments outside of pollen season for allergens to which the patient has demonstrated positivity. [28:09] Looking at the epidemiology, both EoE and food allergy are atopic disorders. You see an increased prevalence of asthma, hay fever, eczema, and even allergic proctocolitis in infancy. You see an enrichment of one disorder to another. [28:29] The overlap of food allergy to EoE is stronger than you might expect. About 30 to 40% of patients with EoE will also have IgE food allergy. A higher rate will have IgE positivity, whether or not that food is a trigger of immediate symptoms. [28:48] Patients with food allergies are about four times more likely to have EoE than the general population. That's a stronger association than the risk of eczema or other atopic conditions to EoE. [30:09] There are differences between IgE food allergy and EoE. The presence of IgE gives a useful tool for identifying the food trigger in food allergy, but not in EoE. Identifying rare triggers in EoE patients is done by clinical observation. [31:46] Epinephrine and antihistamines are not useful in treating EoE. Blocking IgE with Omalizumab has not been effective in trials in treating EoE. PPIs, topical steroids, and dupilumab are helpful for many EoE patients. [32:38] Dupilumab has been evaluated a bit in food allergy in combination with OIT, and there was no statistically significant benefit from dupilumab in food allergy. [33:25] A group in Pennsylvania has been evaluating epicutaneous immunotherapy as a modality to treat EoE. It's also being evaluated for IgE food allergy. Dr. Shreffler thinks it's something to keep an eye on. [33:40] The oral route for immunotherapy can drive EoE for patients. As they become less sensitive from an immediate reactivity viewpoint, a significant percentage of patients develop GI symptoms. This has also been observed with sublingual therapy. [34:14] Iatrogenic EoE, caused by the treatment, may resolve on the cessation of the immunotherapy treatment. [36:25] Dr. Shreffler says in some cases, the shared decision is a decision where he has a strong evidence-based opinion. In some cases, there's a lot more room for a range of clinical decisions that could be equally supported by what we know right now. [36:57] We've said that EoE is a contraindication for OIT. There is a shift happening. Dr. Shreffler sits with families and has a conversation about restricting diet or trying chronic therapy and keeping an ad-lib diet. [37:38] What about doing the same thing by treating the immediate-type food allergy with chronic allergen exposure and then ameliorating the effects of EoE if it emerges, with another therapy? A hundred providers would have a diversity of responses. [38:19] When there is a history of EoE in a family, Dr. Shreffler advocates for getting a baseline scope. It becomes an important “ground zero.” [38:28] The goal is to have less invasive ways to monitor these conditions. [39:32] Chronic inflammation, which is the hallmark of EoE, is well-targeted by therapies like PPIs and steroids. Steroids don't help with IgE-related food allergies. They're not effective at blocking the IgE-driven immediate response. [41:13] Until recently, IgE food allergy has only been managed with avoidance. We have some other tools now. Xolair is not effective in EoE but is effective in two-thirds to three-quarters of patients with immediate-type food allergies for preventing anaphylaxis. [41:45] Dr. Shreffler refers to an upcoming study on the effectiveness of Xolair in treating people with food allergies. Those who were able to tolerate a minimum amount were allowed to begin consuming allergen. We'll get insight into how those patients did. [43:08] Food-induced immediate response of the esophagus (FIRE) is immediate discomfort with exposure to some allergens. Dr. Shreffler explains it. Data supports that these patients are experiencing an IgE-mediated but local response to those triggers. [44:59] If FIRE is IgE-mediated, it may be that Xolair would help suppress it in these patients. It's worth looking at Xolair for this subset of EoE patients. [45:20] Ryan invites any listeners who want to learn more about FIRE to check out episode #34 with Dr. Nirmala Gonsalvez. [45:37] In the paper, Dr. Shreffler wrote about what he hopes will be the practical usefulness of the finding, the intersection between IgE food allergy and EoE. [45:56] A subset of Th2 T cells express a protein called GPR15. It appears to be a marker for the subset of cells that are playing a role in the EoE. [46:36] Caitlin Burk's work now is looking at their activation status in active disease and post-diet elimination and remission. She is developing a data set that is leading us toward the possibility of focusing on that cell subset and techniques to adopt in clinics. [47:12] She is also working out more advanced techniques to look at the receptors. Dr. David Hill at CHOP is working on similar research. This research has the potential to lead to the development of better tests for EoE. [47:44] Holly tells Dr. Shreffler this has been such an informative episode with so many tidbits of things to help patients advocate for themselves. Holly thanks him for sharing all of that. [48:12] Dr. Shreffler is trying to see what can be utilized from their research to make non-invasive tests to identify food allergen triggers for patients so they don't have to go through so many endoscopies. He sees it as a huge unmet need. [48:31] Ryan thanks Dr. Shreffler for joining us. For our listeners who would like to learn more about eosinophilic disorders, including EoE, please visit APFED.org and check out the links in the show notes. [48:41] If you're looking to find a specialist who treats eosinophilic disorders, we encourage you to use APFED's Specialist Finder at APFED.org/specialist. [48:50] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at APFED.org/connections. [49:00] Ryan thanks Dr. Shreffler for joining us today for this interesting conversation. Holly also thanks APFED's Education Partners Bristol Myers Squibb, GSK, Sanofi, and Regeneron for supporting this episode. Mentioned in This Episode: Dr. Wayne Shreffler, MD, Ph.D., Chief of Pediatric Allergy and Immunology and Co-Director of The Food Allergy Center at Massachusetts General Hospital “Triggers for eosinophilic esophagitis (EoE): The intersection of food allergy and EoE” Dr. Caitlin Burk Dr. David A. Hill APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, GSK, Sanofi, and Regeneron. Tweetables: “This fascinating problem of food allergy: why does the immune system do that for some people — recognize what should be nutritive and innocuous sources of energy as an immunological trigger? ” — Dr. Wayne Shreffler “A food allergy; because there is this IgE antibody, we can do skin tests. We can measure that in the blood. It's a useful marker for helping to identify which foods are the trigger.” — Dr. Wayne Shreffler “EoE is tricky because there's not that clear and easy temporal association between an offending allergen exposure for most people and their symptoms. People don't associate the symptoms with the triggers.” — Dr. Wayne Shreffler “Everything is shared decision-making. In some cases, it's a shared decision where I have a strong evidence-based opinion. In some cases, there's a lot more room for a range of clinical decisions that could be equally justified.” — Dr. Wayne Shreffler “Steroids don't help with IgE-related food allergy. They're not effective at blocking that IgE-driven immediate response.” — Dr. Wayne Shreffler “I'm trying to see what we can utilize from our research to make non-invasive tests to identify food allergen triggers for patients so they don't have to go through so many endoscopies. I think that's a huge unmet need.” — Dr. Wayne Shreffler
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In this podcast, I discuss many of the HY skin and soft tissue infections you need to know for your exam. Easy points if you devote time to learning them. Quick errata: for leprosy, the lepromatous form is a TH2 issue, the tuberculoid form is a TH1 issue. I mixed the numbers up in the … Continue reading DIP Ep 570: The Clutch Skin and Soft Tissue Infections Podcast (Step 1-3) + Minor Correction
Liz & Becca dive deep into the complexities of the immune system, breaking down the difference between TH1 and TH2 responses. Discover how an imbalanced immune system could be the root cause of everything from chronic fatigue and autoimmunity to recurring infections and inflammation. They explore the triggers, symptoms, and actionable strategies to restore balance, from fasting and peptides to functional testing. If you've ever wondered why your body feels stuck in a cycle of stress and symptoms, this episode will give you the tools and insights to finally move forward. ***
In this episode of Derms and Conditions, host James Q. Del Rosso, DO, welcomes Mona Shahriari, MD, associate director of clinical trials at Central CT Dermatology and assistant clinical professor at Yale University, to discuss the challenges of treating pregnant and breastfeeding patients, particularly those with atopic dermatitis (AD). The conversation addresses a crucial yet often unclear topic for dermatologists: balancing safety and efficacy when managing AD in patients during pregnancy and lactation. Dr Shahriari emphasizes the importance of addressing uncontrolled inflammation, which can have potential consequences for both the mother and baby, such as premature birth and maternal sleep disruption. She shares insights into the physiological changes during pregnancy, including the shift from a Th1 to a Th2 immune state, and how this can impact conditions like AD and psoriasis. The discussion highlights the limited data available for systemic treatments in this population, as pregnant women are excluded from clinical trials. Despite this, therapies like dupilumab and cyclosporine are discussed for their safety profiles, with dupilumab often considered when patients need effective control with minimal risk. Dr Shahriari also addresses strategies to involve partners in treatment decisions, ensuring patients feel supported and informed. Drs Del Rosso and Shahriari emphasize the importance of open communication with patients, managing risk tolerance, and understanding the nuances of systemic treatment in pregnancy and lactation. Dr Shahriari shares real-world cases, including the use of dupilumab in a pregnant patient with severe AD and counseling a patient with psoriasis who unintentionally administered a biologic injection during the first trimester. Tune in to the full episode for practical guidance on navigating these complex cases and balancing patient care with available evidence. This episode is a must-listen for dermatologists managing pregnant or breastfeeding patients with inflammatory skin conditions.
In today's episode, I am joined by the incredible Sahar Swidan, PharmD, a pioneer in integrative and functional medicine. Dr. Swidan is President and CEO of NeuroPharm and Former CEO of Pharmacy Solutions in Ann Arbor, MI and Adjunct Associate Professor of Clinical Research and Leadership at George Washington University School of Medicine and Health Sciences, and Adjunct Clinical Associate Professor of Pharmacy at Wayne State University. She is an internationally renowned speaker in the areas of pain management, headaches, and HRT. She has authored several book chapters, articles, and patient education material in head and general pain management and personalized medicine. In this talk, we explored the transformative power of combining East and West medicine, the mechanisms behind low-dose naltrexone (LDN), and its applications in autoimmune diseases, inflammatory conditions, and beyond. Plus, we dove into the burgeoning use of ketamine in mental health and pain management. Today's Topics: - Intro (00:00 - 01:58) - Dr. Swidan's Journey: From academia to integrative medicine.(01:58 - 03:00) - East Meets West: The magic of combining traditional and functional medicine.(03:00 - 05:58) - Crunchy Munchy vs. Allopathic Medicine: Why balance is key.(05:58 - 12:43) - Low-Dose Naltrexone (LDN): What it is and how it works.(12:43 - 17:27) - Immune Modulation with LDN: Balancing TH1, TH2, and histamine pathways.(17:27 - 24:58) - Inflammation and Autoimmune Conditions: How LDN helps.(24:58 - 29:26) - LDN as a Gerotherapeutic: Slowing down inflammation-driven aging.(29:26 - 35:57) - LDN for Crohn's Disease and IBD: Real results and gut healing.(35:57 - 43:03) - LDN and Hashimoto's: Reducing antibodies and improving thyroid function.(43:03 - 46:34) - Ketamine in Medicine: Treating depression, PTSD, and chronic pain. (46:34 - 48:22) - Rapid Antidepressant Effects: Why ketamine works so fast.(48:22 - 53:53) - Ketamine for Fibromyalgia: A potential game-changer.(53:53 - 01:06:36) - Ketamine Risks and Safety: What patients and clinicians need to know. (01:06:36 - 01:18:17) ***** Learn more about Dr. Swidan: https://sahar.world/ *****Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/ *****Connect with Enovative Wellness Center on Facebook: https://www.facebook.com/GregJonesNMD
An autoimmune disease is a condition in which the immune system attacks its own tissues. It is typically characterized by low regulatory T-cells and high Th17 and Th2 cells. T-reg cells prevent autoimmune diseases by supporting an appropriate immune response. There are natural ways to support your immune system so that it operates at an optimal level. Poor gut health and gut inflammation can block the function of vitamin D3. Without enough vitamin D, T-reg cells do not work properly. The majority of the population is vitamin D-resistant. To support the immune system, you need 8,000 to 10,000 IU of vitamin D daily, but even more to overcome resistance. Poor gut health, inflammation, and low vitamin D are a perfect storm for developing an autoimmune condition. B. infantis and L. reuteri are vital for your immune system, but many people don't have them because these probiotics are very sensitive to antibiotics. These two important microbes help prevent autoimmune diseases, greatly affect T-reg cells, and suppress inflammatory immune cells. L. reuteri helps increase oxytocin, one of the most potent anti-stress hormones. High cortisol levels mean high stress, which suppresses the immune system. The best way to consume l. reuteri is to cultivate it in a dairy product. If you're low in selenium, you will have higher amounts of inflammatory immune cells. Selenium helps lower Th17, Th2 cells, and auto-antibodies involved in autoimmune disorders. Prolonged fasting can improve your immune system by increasing T-reg cells and creating new stem cells. L. reuteri strain https://www.amazon.com/BioGaia-Osfort... Super Gut book link: https://amzn.to/4dIxTy2 Yogurt Recipe: https://www.culturedfoodlife.com/reci... **I am finding that using only ONE TBS of prebiotic fiber in the recipe makes a better-quality product. How to Make It: https://drdavisinfinitehealth.com/201...https://www.culturedfoodlife.com/l-re... MICROBIOME MASTER CLASS WEBSITE: https://innercircle.drdavisinfinitehe... Yogurt Maker—https://lvnta.com/lv_lrJY1A8ZLtxmwUpYdX Yogurt Jars—https://lvnta.com/lv_qB2B90JNh0hQjaMoXk Yogurt Containers—https://lvnta.com/lv_SFt3wnanoNkBHrf0Rs
Your immune system is so much more than just fighting off the occasional cold. It is deeply connected to EVERYTHING in your body and can be a primary root cause of many common (but not normal) health issues! From chronic fatigue, IBS, and painful periods to stubborn weight loss resistance, skin issues, and more the immune system plays a role! In this episode, we're diving deep into how your immune system works, what happens when TH1, TH2, and TH17 cells go into overdrive, and the signs that your immune system might be out of balance. If you're dealing with autoimmune conditions, chronic inflammation, or mysterious symptoms that just won't go away, this episode is for you. I'll be breaking down how to spot the signs, understand your body's signals, and most importantly, what you can do to support and rebalance your system based on your unique symptoms and health history. If you need help getting to the root cause of your health issues or symptoms click here to apply for coaching!
TWiP reviews a study showing that intestinal helminth infection impairs vaccine-induced T cell responses through an IL-10 pathway, which compromised protection against antigenically drifted SARS-CoV-2 variants. Hosts: Vincent Racaniello, Daniel Griffin and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Worms impair COVID vaccines (Sci Trans Med) Heligmosomoides image (Wiki Commons) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees
BUFFALO, NY- August 16, 2024 – A new #review was #published as the #cover paper of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 15, entitled, “Types of cell death and their relations to host immunological pathways”. Various immune pathways in the host, such as TH1, TH2, TH3, TH9, TH17, TH22, TH1-like, and THαβ, have been identified. While TH2 and TH9 responses primarily target multicellular parasites, host immune pathways against viruses, intracellular microorganisms (like bacteria, protozoa, and fungi), and extracellular microorganisms utilize programmed cell death mechanisms to initiate immune responses and effectively eliminate pathogens. In their review, researchers Kuo-Cheng Lu, Kuo-Wang Tsai, Yu-Kuen Wang, and Wan-Chung Hu from Taipei Tzu Chi Hospital, Fu Jen Catholic University, Taoyuan Armed Forces General Hospital, Tri-Service General Hospital and Ming Chuan University, reviewed these cell death pathways associated with the host immunological pathways. "These relationships can help us understand the host defense mechanisms against invading pathogens and provide new insights for developing better therapeutic strategies against infections or autoimmune disorders.” DOI - https://doi.org/10.18632/aging.206035 Corresponding authors - Wan-Chung Hu - Wanchung.Hu09@tzuchi.com.tw Video short - https://www.youtube.com/watch?v=oPaevm0vpR8 Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206035 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, apoptosis, autophagy, ferroptosis, necroptosis, NETosis, pyroptosis About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
In this episode, we sit down with Dr. John Lewis, a leading expert in nutritional research and the therapeutic potential of Aloe polysaccharides. Dr. Lewis shares insights from his groundbreaking studies on Alzheimer's disease, multiple sclerosis (MS), and the broader impacts of Aloe polysaccharides on immune function and brain health. Key Topics Discussed Understanding Aloe Polysaccharides What are Aloe polysaccharides? How are they extracted and formulated for nutritional supplements? Research on Alzheimer's Disease and Multiple Sclerosis Overview of Dr. Lewis's studies on Alzheimer's disease and MS. Impact of Aloe polysaccharides on cognitive function and disease progression. Immune System Modulation Effects of Aloe polysaccharides on CD4 to CD8 ratios. Regulation of key cytokines: TNF-alpha, VEGF, and BDNF. Balancing TH1 and TH2 responses. Brain Care Formulation Detailed discussion on the Brain Care formulation developed by Dr. Lewis. Clinical results and patient outcomes. Challenges in Nutritional Research Funding difficulties for nutritional and supplement research. Issues with the pharmacological model of placebo-controlled randomized double-blind trials. Why this model is challenging for evaluating supplements and nutritional interventions. Future Directions and Innovations Potential future applications of Aloe polysaccharides in other health conditions. Innovations in nutritional research methodologies. Key Takeaways Aloe Polysaccharides: Naturally occurring compounds with significant therapeutic potential, particularly in modulating immune function and supporting brain health. Clinical Research: Dr. Lewis's studies highlight the positive effects of Aloe polysaccharides on Alzheimer's disease, MS, and overall immune health. Nutritional Research Challenges: The current pharmacological model of clinical trials poses challenges for the study of supplements, necessitating new research approaches. Research References Studies on Alzheimer's disease and Aloe polysaccharides: Positive impacts on cognitive function and disease markers. Research on MS: Aloe polysaccharides and their role in managing symptoms and progression. Immune modulation: Detailed findings on CD4/CD8 ratios, cytokines (TNF-alpha, VEGF, BDNF), and TH1/TH2 balance. Dr. John Lewis provides compelling evidence on the health benefits of Aloe polysaccharides and underscores the need for innovative research methodologies in nutritional science. This episode offers valuable insights for anyone interested in the intersection of nutrition, immune function, and brain health.Connect with Dr. John Lewis Website: Dr. John Lewis Nutrition If you want to get Daily Brain Care visit our online curated range of cutting edge longevity and anti-aging supplements at BIO John E. Lewis, Ph.D. is the Founder and President of Dr Lewis Nutrition™. Dr. John E. Lewis has spent most of his career developing a unique approach as someone who "walks the walk" through all of his combined professional and personal experiences to attaining optimal health through nutrition, dietary supplements, and exercise. Throughout his research career, he has evaluated many different nutritional approaches to enhancing well-being, particularly for brain health, immune function, and counteracting aging. He can separate fact from fiction regarding how to utilize nutrition and dietary supplements to help you achieve and maintain optimal health. If you need a trusted source of information, products, and services, then look no further than Dr. Lewis and how he can help you achieve your health-related goals. Professional Career Dr. Lewis is past full-time Associate Professor in the Department of Psychiatry and Behavioral Sciences at the University of Miami Miller School of Medicine and the Founder and President of Dr Lewis Nutrition™. He is a Diplomate, Faculty Member, and Advisor of the Medical Wellness Association. He has been the principal investigator of over 30 different studies on human health in his research career. During that time, he either directly raised or indirectly supported raising over $23 million in grants, gifts, and contracts for research studies and clinical trials and educational programs for medical students. In addition to his research, Dr. Lewis has been an invited national and international lecturer and guest speaker at conferences and as a guest on television shows. He is a well-known author with over 180 peer-reviewed publications in some of the world's leading scientific journals. He has also mentored many different students, from undergraduates to post-doctoral trainees, in not only how to conduct clinical research but to apply the principles of health promotion into daily practice. Research Interests Much of Dr. Lewis's research has focused on evaluating the effects of nutrition, dietary supplements, and exercise on various aspects of human health. He and his colleagues have been continually searching for ways to help people achieve and maintain health through natural treatments that align with our physiology. A primary stimulus for the origin of Dr Lewis Nutrition™ occurred after Dr. Lewis ran his landmark study on how an aloe polysaccharide multi-nutrient complex improved cognitive and immune functioning after 12 months in persons with moderate to severe Alzheimer's disease, leading to the creation of the dietary supplement, Daily Brain Care. Daily Brain Care showed clinically and statistically significant improvements in cognition according to the ADAS-cog cognition score and statistically significant improvements in inflammation (according to TNFα and VEGF), immune function (according to the CD4/CD8 ratio), and adult stem cells (according to CD14+ cells). His seminal publication from the study in the Journal of Alzheimer's Disease not only spurred him to leave academics and pursue a science-based business career, but also enabled him to be selected for a widely-acclaimed TEDxMiami talk. Founding Dr Lewis Nutrition™ While Dr. Lewis still maintains an academic affiliation, he chose to leave a full-time research career to pursue his true passion of helping people achieve health through nutrition, dietary supplements, and exercise. His research in brain health and immune function was key in the creation of Daily Brain Care, but afterward he chose to shift into business where the opportunity to reach a larger audience is greater. Dr Lewis Nutrition™ is the vehicle through which Dr. Lewis leverages his many years of personal and professional work to spread a message of health that is so desperately needed, particularly for those who are afflicted with an all-too-common chronic disease, e.g., neurodegeneration, immune dysfunction, or cardiac and metabolic disorder. Dr. Lewis will continue to be a thought leader to help people utilize the power of nutrition and dietary supplements and learn how to take control of and optimize their health. Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with: Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals Nutristat Omega 3 to 6 status and more Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission. Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to https://www.buymeacoffee.com/LisaT to donate $3 Lisa's Anti-Aging and Longevity Supplements Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world. This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life. Subscribe to our popular Youtube channel with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge" Check them all out at https://shop.lisatamati.com/collections/books Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here: Use code "tamati" at checkout to get a 10% discount on any of their devices. Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38 Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa and team
Ever wonder why your body reacts so intensely to seasonal allergies? In this episode of Sick Health With Kevin Ban, MD, we'll go on a journey with dual-board certified immunologist and internal medicine physician Dr. Tania Elliot, exploring the fascinating science behind allergic reactions. Imagine this: your body's ancient system for eliminating parasites is just plain old BORED. With nothing much to do in the modern world where parasites are at a minimum, your Th2 cells will attack just about anything to keep busy. Conversely, in underdeveloped locations, where parasites run rampant, allergic responses are almost non-existent. In just 45 minutes, here's just some of the information you'll master:1. You'll discover the intricate mechanisms of allergic responses.2. You'll learn about common myths surrounding allergies and their debunking.3. You'll understand how allergies impact everyday health and wellbeing.4. You'll gain practical tips to manage and mitigate allergic reactions effectively.Make sure to subscribe, like, comment, and share. We want to make sure we put the power of healthcare in YOUR hands. RESOURCES MENTIONED IN THIS EPISODE:American College of Allergy, Asthma and Immunology: https://acaai.org/American Academy of Allergy, Asthma and Immunology: https://www.aaaai.org/SHARING BEAUTYAdore You, by Harry Styleshttps://www.youtube.com/watch?v=VF-r5TtlT9w ←- Note, the music video version does not really correlate to what Tania is talking about, so I suggest linking to the lyric video instead: → https://www.youtube.com/watch?v=iquhBgM-Qv0Find Tania at: https://www.youtube.com/@drtaniaelliottDr. Tania Elliott, MD, FAAAAI, FACAAI, is a leading authority in her field and a prominent health influencer, with over 40 million views across platforms. She is dual board-certified in Internal Medicine and Allergy/Immunology and serves as a Clinical Instructor at NYU Langone Health. As a spokesperson for the American College of Allergy, Asthma, and Immunology, Dr. Elliott is dedicated to addressing the widespread medical misinformation and providing a trustworthy source of health information.Dr. Elliott is also the founder of Modern Medical, a consulting firm that provides strategic, operational, and advisory support across all healthcare sectors. As a seasoned healthcare executive, she started Modern Medical to drive innovation and change in the industry. The firm helps clients leverage technology and IoT to enhance patient experience, improve practice efficiency, and reduce costs. Modern Medical also empowers clinicians to explore new career paths and adapt to emerging care delivery models. Through Modern Medical, Dr. Elliott aims to address the challenges facing today's healthcare infrastructure and create sustainable, effective solutions for the future.Through her impactful contributions to the field, Dr. Elliott has become a recognized thought leader, earning accolades such as being named one of Medical Marketing and Media's (MM+M) top 40 Healthcare Transformers in 2019 and one of Health Tech Magazine's Top 30 Healthcare IT Influencers to Follow in 2023. In addition to her media presence, she is a sought-after public speaker and keynote presenter at national medical conferences and meetings. Frequently featured on major television shows, including Good Morning America, CBS Mornings, Today Show, Good Day NY, and Live with Kelly and Mark, Dr. Elliott continues to inspire and inform a broad audience. Her expertise and influence position her at the forefront of the healthcare industry, making a significant impact.To see any images and leave your questions or comments, find us on YouTube at https://www.youtube.com/@SickHealthwithKevinBanMD
In today's episode, we explore the role of Thymosin Alpha 1 Peptide in modulating the immune system, specifically its effects on Th1 and Th2 responses. The episode further delves into the mechanisms by which Borrelia burgdorferi evades immune detection and offers strategies to enhance immune effectiveness against this stealthy pathogen. Additionally, we discuss the broader implications of immune modulation in chronic Lyme disease and mold exposures. Topics: Introduction Recap of the series on Lyme and mold Highlighting the key steps in the biotoxin illness resolution process Importance of working with a medical professional Key Steps in Biotoxin Illness Resolution Lowering inflammation Lipid replacement therapy (phospholipids) Use of antimicrobial and antiparasitic herbs for Lyme and coinfections Employing binders to eliminate toxins and reduce inflammation Checking for MARCoNS and utilizing treatments like silver spray or biofilm busters (e.g., xylitol) Detoxification post-MARCoNS clearance using agents like chlorella and glutathione Assessing and normalizing various health markers (e.g., ADH, osmolality, MMP9, C4a, C3a, TGF-beta, sex hormones) Additional Resources and Episodes Early stages of Lyme infection and Herxheimer reaction: Episode 116 Chronic inflammation and biotoxin management: Episode 117 Role of binders in interrupting enterohepatic circulation and toxin elimination Discussion on Biofilm Importance of addressing biofilm in antimicrobial therapies Potential supplements and strategies (e.g., garlic, oil of oregano, stevia) Overview of Lyme Disease Impact & Immune Function Chronic inflammation due to miscommunication between the innate and adaptive immune systems + dysregulated adaptive responses How borrelia evades the immune responses Immunomodulation in Lyme Disease Background on immune modulation Role of T cells in adaptive immune response Th1 and Th2 cell imbalance in chronic Lyme Strategies to support Th1 cells and decrease Th2 response Focus on Thymosin Alpha 1 Benefits of Thymosin Alpha 1 in modulating immune function Promoting Th1 response and managing Th2 dominance Effects on regulatory T cells (Tregs) and immune tolerance Conclusion Reminder to work with a Lyme literate or biotoxin illness literate medical professional Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! Or visit linktr.ee/synthesisofwellness to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
Allergy season is upon us, and many are relying on medications like Benadryl, NyQuil, and Dramamine, which have been linked to an increased risk of dementia with long-term use. In this informative episode, I share the comprehensive protocol that helped me and numerous patients overcome allergies once and for all. We'll dive deep into the underlying causes of allergies, exploring the intricate interplay between the immune system, environmental factors, and gut health. From reducing toxic burdens and balancing the Th1/Th2 immune response to healing the gut and restoring beneficial bacteria, this episode provides a holistic blueprint for resolving allergies at their root. Get ready to bid farewell to the misery of sneezing, congestion, and itchy eyes as we uncover the path to lasting relief without the side effects of conventional medications. Show Notes: Understanding Allergies: Causes, Symptoms, and Common Allergens Genetic and environmental factors contributing to allergies Type I hypersensitivity reaction and the role of IgE antibodies Common allergens: environmental, food, insect, drug, and contact allergens The Overflowing Cup: Why Allergies Worsen Over Time Toxic burdens: environmental toxins, home toxins, inflammatory foods The impact of stress on the immune system's capacity Conventional Allergy Treatments: Effectiveness and Side Effects Over-the-counter and prescription medications: antihistamines, decongestants, corticosteroids Potential side effects: drowsiness, dry mouth, cognitive impairment, dementia risk The Naturopathic Approach: Treating the Whole Person and Getting to the Root Reducing the toxic burden Balancing the Th1 and Th2 immune response Healing the Gut: A Four-Step Process Recommended Resources and Further Reading: https://ndnr.com/autoimmuneallergy-medicine/allergies-a-route-to-resolution/ === Thank you to our sponsors! AquaTru https://aquatru.com and use code DRG for 20% off all products. Nuzest https://nuzest-usa.com/drg and use code DRG for 20% off all products. === Be sure to like and subscribe to #HealThySelf Hosted by Doctor Christian Gonzalez N.D. Follow Doctor G on Instagram @doctor.gonzalez https://www.instagram.com/doctor.gonzalez/ Visit https://www.elm.health/ to work directly with Dr. G.
Whether you're a parent concerned about your child's allergies or an allergy sufferer seeking relief, this episode promises to broaden your understanding and bring hope about available treatments! Dr. Gina Dapul-Hidalgo is a board-certified pediatric and adult allergy and immunology specialist, and she explains what allergies really are: the immune system's overreactions to typically harmless substances in the environment. She and Dr. Amigues discuss the different types of allergies, how antibodies work, and the effect of environment on allergies. Dr. Dapul also dives into allergen immunotherapy (desensitization), one of the oldest and most helpful methods for treating allergies. You've probably heard of allergy shots; these can decrease the sensitivity to allergens, reduce the need for medication, and are the closest thing to a cure for allergies! We'll end on a discussion about TH1 and TH2 cells, and the benefits of exposing children to dirt and germs for a resilient immune system. Getting dirty in nature is good for us!
Pet allergies can range from mild to severe — from a nuisance to, occasionally, anaphylaxis. When all you've got is some itchiness and a runny nose, are you doomed to a life without a furry friend?Norman and Tegan discuss the possibility of building up a tolerance to allergens. Got a health question? Shoot us a line @ABCHealth on Instagram, or send a voice memo to thatrash@abc.net.au. We'd love to hear from you!Looking for COVID-19 updates? Don't panic, they've moved over to The Health ReportReferences: Dog ownership at three months of age is associated with protection against food allergySensitisation, asthma, and a modified Th2 response in children exposed to cat allergenSpecific gut microbiome signatures and the associated pro-inflammatory functions are linked to paediatric allergy and acquisition of immune tolerance
In this episode, hosts Jordan Briggs and Marcus White are joined by the insightful Dr. Stewart Gillespie to unravel the mysteries of the immune system. Dr. Gillespie provides valuable insights into the innate and acquired immune systems, shedding light on crucial concepts such as Th1, Th2, Th9, and Th17. Explore the complexities of immunology as the conversation delves into practical tools and hacks to fortify your immunity in the face of modern health challenges. Dr. Gillespie shares actionable tips to empower your immune system and enhance overall well-being.
Who has ever felt travel hungover? Who fears travel because you might have a chronic illness flare or the unknown away from your healing home? Look I get it, travel used to make me so dang anxious. It took a whole entire routine just to feel good at home, throwing travel in as a variable to the mix was just plain hard! Until I learned the secret tricks and tools that helped me heal my 8 different autoimmune diseases into remission while I traveled, and see the world all at the same time! Nowadays, I feel like my superhuman self and enjoy traveling at least 1-2 times a month. I want you to remember that your body is not broken, if you have AUTOIMMUNE DISEASE you can 100% heal. Travel may just be one of the necessary ingredients with a few necessary directions. So buckle up, press play, and let's go full speed ahead into this episode! Show notes: WATCH this episode here: https://www.inspirehealthbyjen.com/heal-your-autoimmune-symptoms-signup AUTOIMMUNE HEALING RESEARCH GROUP WAITLIST: https://www.inspirehealthbyjen.com/heal-your-autoimmune-symptoms-signup WORK WITH JEN 1-1 https://www.inspirehealthbyjen.com/discovery-call HEALING RETREAT: https://www.inspirehealthbyjen.com/retreats IN-HOME INFRARED SAUNA: https://www.inspirehealthbyjen.com/infrared-therapy CONNECT WITH JEN: https://www.inspirehealthbyjen.com/work-with-jen INSPIRE HEALTH FACEBOOK GROUP: https://www.facebook.com/groups/inspirehealthhealing/ Have a question? Send a request and we may feature it on a future episode!: https://forms.gle/bbpYJKTPhmsezYs3A Study mentioned:Assaf, A. M., Al-Abbassi, R., & Al-Binni, M. (2017). Academic stress-induced changes in Th1- and Th2-cytokine response. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 25(8), 1237–1247. https://doi.org/10.1016/j.jsps.2017.09.009 Free Guide(s): One Day Detox Recipes: https://www.inspirehealthbyjen.com/subscribe-to-pdf Full Moon Meditation: http://www.inspirehealthbyjen.com/subscribe-for-full-moon-meditation Energy Healing Audio: https://www.inspirehealthbyjen.com/energy-healing-audio-download Find Out More: www.inspirehealthbyjen.com Blog: www.middaypigeon.com If you have questions or would like me to help you get started… Let's get in touch and begin your true path of healing today. Your body and your mind will eternally thank you!
Atopic dermatitis should be viewed as a syndrome rather than a singular disease. Between genetics, skin barrier, environment, microbiome, TH2 immunity, etc. there are so many factors that play a role which is why dermatologists always mention a multimodal approach.Check out more details on this week's episode of The Derm Vet podcast!
Please Follow us and hit the bell to be notified when new episodes drop. Don't forget to Rate this episode and leave a comment. Rate and review your favorite episodes to let me know the things you like so I can keep delivering great content that brings value to your life and health. Check out my online store for self-learning/DIY programs for thyroid, gut health and detox. You can use this form to reach out and request an Initial Consultation! Visit my LabShop store to self-order the same tests I use with my one-on-one coaching clients. https://www.drnoseworthy.com/site/contact Follow us on social media Facebook Instagram You can also listen on Apple and Spotify - and all other major podcast platforms. https://www.instagram.com/drnoseworthyhttps://www.facebook.com/becomeautonomoushttps://www.tiktok.com/@drsnoseworthy
This episode was originally published on April 18th, 2017 on SelfHacked Radio - now known as The Joe Cohen Show. It's been 6 years since this episode aired, and yet a lot of health issues that were mentioned, alongside revolutionary health strategies that Dr. Gundry shares, are still more relevant than ever! In an episode that clearly shows Dr. Gundry was way ahead of his time, Joe and Steven Gundry discuss the prominence of leaky gut, how inflammation is the cause of the majority of health issues, and the root cause of all of this - LECTINS! You'll also discover the best ways to approach an elimination diet and how to optimize your gut health! - Check out SelfDecode - Join Joe's online community - Follow Joe on Instagram Timestamps: (0:00) - Intro (15:52) - Lectins number one cause of gut issues? (22:15) - TH2 dominance and the immune system (27:55) - The process of healing your gut to introduce more foods (31:49) - Starting with a lectin-free diet (34:17) - Fiberous carbs vs non-fiberous carbs (44:17) - Low histamine foods relation to lectins (48:00) - The cannabinoid system and the CNR1 Gene (52:48) - Best probiotics to restore the gut (55:52) - Most important supplements to take (58:56) - Keto Plant Paradox (1:01:47) - Animal protein and mTOR
In pursuit of mechanisms and evidence-based approaches, gut health has been revealed as a critical cornerstone of neurological health. In this episode, we're going into detail on what the gut layers are. I hope this video will help someone else who's trying to understand how the gut works for purposes of biohacking with functional medicine, nutrition, supplements, etc. For any intervention, is there evidence of a relationship, and is there data that it worked in other humans? We talk about: what the gut mucus is made out of elements of the gut barrier - the many ways the body keeps microbes and partially digested food away kinds of intestinal epithelial cells (Goblet cells, Paneth cells, M cells, etc.) and their functions types of gut associated lymphoid tissue (GALT) and their distinctions - lamina propria, Peyer's patches, lymph nodes the enteric nervous system and enteroendocrine cells different types of CD4+ T cells: Th1, Th2, Th17, and Treg, what they respond to, and their major outputs the mechanism of nutrient absorption the mechanism of leaky gut (paracellular transport through tight junctions) Here's the video: https://youtu.be/sIn_VxH6zDA Transcript of the video, for those who are pressed for time: https://www.brainforest.org/post/leaky-gut-anatomy I hope this helps someone understand their gut a little better on the path to health. Stay tuned for our next podcast on the relationship between leaky gut and aging. Share this resource with others who are studying gut anatomy on the path to health!
Sinus problems are rampant. Americans spend over $1 Billion annually to treat sinus problems with over-the-counter medications, which is crazy. It's not just common in the chronic illness world and in the autoimmune world, and ESPECIALLY in the mold world, it's common in everyone. Sinus inflammation is interesting. I have had really great success healing my own sinuses. I'm not recommending that everyone (or anyone) do what I did, but what I REALLY DID was I spent several years intensely studying deep immunology and the Ear, Nose, and Throat and Allergy literature, read 100s of studies, and used things like high dose supplements and essential oils to have really good success with nasal polyps and chronic sinusitis. I haven't had sinus issues for over 3 years. Here is a video of what I did to get rid of nasal polyps, it's crazy. When I talk about sinuses, I'm also talking about ENT areas - ear infections, tonsils, sore throats, pharyngitis, which includes things like Strep and PANDAS, but most of my success was with the nose. The whole ENT region is a hotbed of infections and pathogens, and is right across the wall from the brain, and things like antibodies, histamine, chemical toxins, inflammatory cytokines, and mycotoxins from mold can ride the "olfactory elevator" (as Dr. Jill Crista calls it) right up to the brain - right to deep, midline areas like the frontal cortex (brain fog, etc), pituitary (hormones), amygdala (anxiety, fear, etc), hypothalamus (temp, dysautonomia, etc), neurological dysfunctions and more. Sinus inflammation drives many immune mechanisms, including Th2 and eosinophilic inflammation, mast cell activation and histamine, and Th17 inflammation, which is tissue-damaging autoimmune inflammation and will drive autoimmune progression. THAT IS THE MOST IMPORTANT PIECE OF THE PUZZLE! One thing that can drive this immune activation are chronic biofilms including Strep, Staph (MARCoNS), and Mold/Yeast that are incredibly persistent and antibiotic resistant. Biofilm colonies, like in the gut, grow on sinuses, adenoids, tonsils (that's why they remove them!) and ENT surfaces - and when they adhere to a surface they are over 1000x harder to kill, and they are highly persistent and antibiotic resistant. THIS IS THE OTHER MOST IMPORTANT PIECE! In this episode I talk about 4 levels of supporting sinus inflammation naturally:1 - Breathe Clean Air!!!! Allergies are obviously an issue....You can't be living in mold....I talk about air purifiers, mold candles, HVAC filters, and more.2 - Fix your Gut and Balance your Immune System - I talk about using things like probiotics, herbal killers, SCFA, vitamins D and A, glutathione, perilla, quercetin, luteolin, etc to support barrier integrity, mast cell activation, Th2 dominance.3 - Break Biofilms and Kill Infections - Nasal Spray, Neti Pot, Nebulizer, Gargle - I talk about using essential oils, iodine, hydrogen peroxide, silver, propolis, aqualaurin, biocidin, etc to break up biofilms and help kill pathogens. 4 - Maintain - I talk about the importance of breathing clean air, doing regular nasal rinses, and more to maintain. This is not medical advice, but many people have seen their ENT with very little answer besides antihistamines, antibiotics, or steroids, so these are just some of the things that people are doing out there, and hopefully it can help you solve YOUR puzzle!I also mention this, my favorite newsletter and started by an amazing ENT surgeon:www.sinusitiswellness.com
It's hard to slow down when you're dopamine-dominant. Being highly motivated, fast-paced, and competitive has many benefits, but how can you slow down when it starts negatively impacting your health? Kris Gethin is on the podcast today to answer that, and much more! In this episode, Kris and Joe discuss their thoughts on stem cell therapy, how to choose what supplements to add and remove for optimal fitness, and how Kris uses biohacking to balance his training with his focus on living a long and healthy life. Kris also gives us an inside look at his daily routine and what he focuses on to optimize his diet and nutrition, which has resulted in him achieving a glycan age of 26 at the current chronological age of 48! Kris Gethin is the co-owner of KAGED supplements, co-owner of the Kris Gethin Gyms, owner of Kris Gethin coaching and a hybrid athlete. He is the former editor in chief of bbcom, former editor at large of FLEX and came 2nd in Natural World bodybuilding championships in 2006. - Find Kris Gethin on Instagram @krisgethin - Check out SelfDecode - Join Joe's online community - Follow Joe on Instagram & TikTok Timestamps: (0:00) - Introduction (2:56) - Kris' Daily Routine (10:42) - How Kris chooses his supplements (15:24) - HRV and training (21:18) - The neurochemistry behind overtraining and mood (26:13) - Kris labs and supplements (31:34) - Stem cells (33:50) - Longevity and bodybuilding (42:36) - How to improve glycan age (45:43) - Th1 vs Th2 and megadosing supplements
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.11.519940v1?rss=1 Authors: Theret, M., Messing, M., White, Z., Henry, L. W., Rempel, L., Hamer, M., Hashimoto, J., Li, F. F., Brassard, J., Li, Y., Sauge, E., Shin, S., Day, K., Uppal, M., Low, M., Eisner, C., Sato, S., Akira, S., Bernatchez, P., McNagny, K., Rossi, F. M. V. Abstract: The ability of mesenchymal stromal cells to modulate inflammation is at the basis of the ongoing interest in their therapeutic potential. Yet, reliable success in clinical trials is limited, possibly due to a limited understanding of their impact on the inflammatory milieu in physiological conditions. Here we show that, at steady state, mesenchymal progenitors regulate the balance between type 1 and type 2 inflammatory milieus by acting on innate immune cells through the TAK1-NFkB pathway. Suppressing the constitutive activity of this pathway in MPs leads to skewing of the immune system toward systemic Type 2 inflammation (Th2). These changes have significant effects on diseases with an important inflammatory component, leading to a worsening of disease in a preclinical model of Th2-dependent Asthma, and a reduction of symptoms associated with Th1/Th17-dependent experimental autoimmune encephalitis. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
During this edition of the Thrivality:OutLoud Podcast, Steven Wright is back on the show to discuss his new creation - HoloImmune - which uses a new class of ingredients called ParaProbiotics - or heat treated young probiotics - to rebalance the two branches of your immune system, the Innate and Adaptive or TH1 and TH2. These branches modulate each other but can become imbalanced through stress or illness resulting in a host of problems from respiratory, skin, gut, or overall immune imbalances.And while HoloImmune uses something sounding like a ProBiotic - aka ParaProbiotics - this product is NOT intended for traditional gut flora repopulation; rather, HoloImmue re-estabishes proper cell to cell communication in the gut. Think of Vitamin C, Zinc, Quercertin, NAC as ingredients the immune system uses to do its job. And HoloImmune as the intelligence or “flight plans” to get the immune system rebalanced and “flying” in the right direction.Why you should listen: podcast topics & outline1. Why Steven and his team created the new HoloImmune cell signaling product that reboots the immune systems flight plans2. What are the two (2) branches of the immune system, Innate and Adaptive, where they are located and how they actually work3. The five (5) different ways the immune system can become dis regulated 4. How HoloImmune is different than traditional Immune System ingredients such as Vitamin C, Zinc, Quercertin, etc.5. How HoloImmune supports the Upper Respiratory System, Skin Health, and even those dealing with more complex health issues like Lyme or Mold6. HoloImmune's unique ParaProbiotic ingredients that don't act like a traditional probiotic, but rather intelligently rebalance and modulate the immune system7. Who HoloImmune is for and how much to takeSponsors and Linksa) Discount link for HoloImmune or use the discount code Thrive15 for $15 your first order @ www.HealthGut.com. Offer expires 10/31/2022b) for more information about me, journey, and offerings: http://www.thrivality.com
Everyone's immune systems work a bit differently. Many Canadians have allergic diseases such as asthma, food allergy and allergic rhinitis. These people are subject to Th2 skewing which is when there is more Th2 cytokines in their body. It is unknown if underlying Th2 skewing impacts one's response to the COVID-19 mRNA vaccine. Understanding the […]
Parasites are interesting. That word means different things to different people, some people are terrified of the idea of worms living inside their body, but at the same time parasite cleanses are super trendy on Instagram and social media, and yet some people think that parasite cleansing is the solution to all health problems....which one is it?Parasites are paradoxical in the research world, many areas of the world that have endemic parasitic infections have virtually no autoimmunity, and helminth therapy is actually an incredibly promising treatment for certain autoimmune cases. The reason that parasites are so relevant in the population of people that I see is because of our junk food supply, the toxins everywhere, and the rampant metabolic and immune disruption - - but they aren't always the ONLY culprit, they show up more often with the presence of heavy metals, Candida, SIBO, mold and other toxins. When they are recognized as bad, they elicit a strong and specific immune response that I talk about in detail in the podcast, triggering a Th2 immune response via IL-4 and activating mast cells and histamine, and often keeping someone stuck there (sound familiar??) as they become allergic to more foods, chemicals, and more sensitive to their world. They can also drive inflammatory bowel processes, cause liver and gallbladder issues, disrupt neurotransmitters, infect the brain, and much more. While I certainly do NOT believe that parasites are a piece of every person's health puzzle, I do think "parasite cleansing" can be incredibly helpful in the right situation. In this podcast I share my personal opinions and personal experiences that I have had with parasites (including when I passed one!) and many stories of helping people with them, and they are pretty drastic stories. I also talk about the testing available and what I personally look for, as well as the supplements and protocols I recommend for people and how those are given, and basically everything that I know and think about parasites! Leave a rating, review, share this episode with a friend!!
Ok so let's talk about gut health. Gut health and detox are pretty much the two most important topics, and toxins affect gut health....but good gut health is necessary for proper detoxification.....I think gut health wins. At least for this next podcast series :) Gut health is foundational to health, inflammation, and aging. It's so crucial, but so few people seem to have it mastered IF they are still experiencing symptoms, and I mean ANY symptoms - joint pain, fatigue, anxiety, depression, bipolar, metabolic, certainly autoimmune flares, not just digestive symptoms. I'm going to go deeper into some specific topics in the next few episodes, but this one is an overview, and I made a list of the 10 most important things for gut health. The first 3 are symptoms, the next 4 are mechanisms, and the last 3 are infections, and understanding these 10 things will give you a pretty good grasp on understanding gut health and digestion overall!Diarrhea - I talk about IBS, IBD, low microbiome and good bacteria/probiotics, glutamine, mast cells, and hydrogen SIBO....Constipation - I talk dysbiosis/methane, and a LOT about vagal motor outflow and vagus nerve activity that controls motility as well as HCL, bile, enzymes....Bloating - When I hear bloating I think small intestine and fermentation. Dysbiosis is often at the root, which includes proper digestion (HCL and bile), and I touch on SIBO/SIFO, avoiding FODMAPs foods....Digestion - This is critical!! Chewing your food, being in parasympathetic mode, then proper stomach acid - it can be too high (mast cells) or too low (more common), pancreatic digestive enzymes, bile from the gallbladder (steatocrit), and of course VAGUS BABY!Dysbiosis - The 10 lbs of bacteria in your gut can become imbalanced. Low good bacteria, general microbiome imbalances…..and LPS!!!!!Leaky Gut - Everyone can have some intestinal permeability, is yours pathological, and if so what kind is it - paracellular or transcellular? Food Sensitivities - IgG testing, and how food sensitivities can drive autoimmune reactivity, general inflammatory tone, and initiate T cell mediated tissue damageSIBO - Bloating! Fermentation of fibers, starches, sugars, FODMAPs ...why you need HCL, bile, vagus outflow……Why I think SIBO testing is dumb….Candida - OMG….the single biggest thing I see. Antibiotics, sugar, stress, birth control, mold exposure, can drive a Th17 inflammatory response (autoimmune), can also drive Th2 (and both will decrease Th1)......and why I love urinary organic acids testing for fungal issues.Parasites - this I am going to do a whole episode on because it's crazy, it's quite frankly pretty controversial in the autoimmune world, is it better to have or to not have them??? The answer is IT DEPENDS. But I do talk about someone who was diagnosed with Ulcerative Colitis and it actually seemed to be a parasitic infection, pretty interesting story :)Share this with someone, subscribe, leave a rating and review, and follow me elsewhere!
A stuffy nose (allergic rhinitis) is one of the most common symptoms of allergies, aka hay fever.Millions suffer seasonally, or just randomly, unable to fully appreciate blooming flowers, grassy meadows, furry four-legged pet friends, or other beauties in the environment.I, Dr. Ben, know this quite well first hand, as allergies and asthma kept me from feeling my best during soccer and baseball seasons as a kiddo. The prescription antihistamines and bronchodilating inhalers hardly worked to manage my chronic allergies... but then, everything changed when nature helped to put my immune system into balance. In today's Medicinal Monday episode we cover everything from managing allergy symptoms naturally, the power of nasal diaphragmatic breathing to help the body function in its best form, as well as the intricacies of immune balancing (Th1 and Th2).As always, you can join us live each Monday at 12 PT / 3 ET on the Alter Health YouTube Channel! https://www.youtube.com/alterhealthSome highlights from today's episode on Nose/Sinuses...The nose and sinuses filter and humidify air, providing first line of defense against invading pathogens and toxinsChronic congestion from allergies increases risk for upper respiratory infection including sinus infection and ear infectionAllergy symptoms can be immediately relieved from steam inhalation or alternating compress, as well as some herbs and supplements (nettels, butterbur, NAC, etc)The power of nose breathing to both prevent and reverse chronic congestion (and balance blood pressure, nervous system, oral microbiome, and more)How being too clean/sterile can chronically imbalance the immune system and exacerbate allergies (and other conditions related to Th2 dominance)Links to some more good stuff- Join Alter Health on Locals: https://alterhealth.locals.com/- Cleanse with Us during the next Alter Health Cleanse: https://www.alter.health/cleanse- Work with us in the Thrive on Plants program: https://www.alter.health/thrive-on-plants- ATTN Health Practitioners! Learn more and apply to the Plant Based Mind Body Practitioner Program: https://www.alter.health/pbmb-practitionerPeace and Love.
Eosinophilic Oesophagitis (EoE) is a confronting TH2-dominant disorder mainly picked up in infancy and childhood but not uncommonly missed until adulthood. It's aetiology is unknown although it can occur with atopic conditions such as asthma. EoE can present as vomiting or spitting food up in youngsters but may also present as hiccups or food impaction. It's noteworthy that Coeliac (Celiac) Disease and Ehlers-Danlos Syndrome may be co-morbidities with EoE.Nicole Hannan is an expert in EoE by necessity (her daughter has EoE) and is now completing her PhD in this area and today we learn all about the hallmarks, the prevalence, concomitant disorders, the treatments and the precautions of EoE. Listen in to this full episode and an urgent call-out to both patients and practitioners in a short episode on EoE to further research into this condition.Patients are encouraged to fill out a 15 minute survey using this link .While practitioners are urged to join the focus group if you have cared for a patient with EoE in the past 5 years (06.2017-06.2022).RESOURCES:Hannan N, McMillan SS, Tiralongo E, et al. Treatment Burden for Pediatric Eosinophilic Esophagitis: A Cross-Sectional Survey of Carers. J Pediatr Psychol. 2021 Jan 20;46(1):100-111. Yaxley JP, Chakravarty B. Eosinophilic oesophagitis - A guide for primary care. Aust.Fam Phys. 2015 Oct;44(10):723-727. Gonsalves NP, Aceves SS. Diagnosis and treatment of Eosinophilic Esophagitis. J Allergy Clin Immunol. 2020 Jan;145(1):1-7. Feo-Ortega S, Lucendo AJ. Evidence-based treatments for eosinophilic esophagitis: insights for the clinician. Therap Adv Gastroenterol. 2022 Jan 19;15:17562848211068665 eCollection 2022.
Between 10-30% of the global population experiences allergic rhinitis, otherwise known as "hay fever," which is the most common presentation of environmental allergies.Honestly, I thought allergies were even more prevalent than this. The wide range is likely due to the fact that allergies tend to come and go, which can make them even more difficult to understand and get a handle on.Nevertheless, prescription and over-the-counter allergy medications, such as anti-histamines, are some of the most common pills to be swallowed in our world today. Even with such meds, it can be difficult to manage these symptoms... until now!No, no, no... there aren't any quick fixes to allergies. In fact, reversing allergies is a prime example of playing the long game to allow and encourage the immune system to find its innate balance.In a nutshell, the "allergens" that trigger an immune response aren't bad and we shouldn't have to fear or avoid them. The goal is to retrain and nourish the immune system to offer more resilience. We cover lots of science and strategies for managing and reversing allergy symptoms in today's episode.If you'd like to join these conversations live, be sure to Subscribe to the Alter Health YouTube Channel! https://www.youtube.com/alterhealthSome highlights from today's MM episode...Managing allergy symptoms (+ cold/URI) naturally with steam inhalation, netti pot, and alternating hot/cold compressThe allergy/anti-histamine herbs and nutrients like nettles, butterbur, eyebright, quercetin, Vit C, NACReducing the load of environmental triggers by removing shoes indoors, washing sheets regularly, dusting/vacuuming, HEPA air filter, etcThe importance of balancing Th1 and Th2 immune responses - resolving system inflammation, avoiding immunogenic foods, gut healing, exposure to bacteria/virusesUnderstanding the stress response and its role in the immune systemLinks to some more good stuff- Join Alter Health on Locals: https://alterhealth.locals.com/- Cleanse with Us during the next Alter Health Cleanse: https://www.alter.health/cleanse- Work with us in the Thrive on Plants program: https://www.alter.health/thrive-on-plants- ATTN Health Practitioners! Learn more and apply to the Plant Based Mind Body Practitioner Program: https://www.alter.health/pbmb-practitionerPeace and Love.
In this episode, Dr. Carmen explains how cortisol helps regulate the immune systems TH1 and TH2. What TH1 combats for us and how cortisol impacts it. What TH2 combats and again how cortisol impacts it. Understanding this relationship can help us better understand our labs, how we fight chronic and why we can't (sometimes) fight chronic infection. TH1, TH2, and Cortisol relationship impacts our health, energy, recovery, and the ability for our body to get fitter. If you want to take this work deeper, and apply it to your life we invite you to join us in the New Beginnings Program. We take this work apply it to your daily life, practice it. Unwinding the beliefs that don't serve you and go to work creating ones that move your life to that place you want it to be. Click here for more information: https://www.kimberlyjarmancoaching.com/the-path-to-success-program/ If you are ready to jump in click here to schedule a complimentary consultation call: https://calendly.com/kimberlyjarmancoaching/free-consultation-call For more information about working with Dr. Carmen Jones ND https://www.drcarmenjones.com
HIGHLIGHTS[00:48] Relating the winter Olympics to the nobility of the sports[05:15] Unravelling Nathalie's identity, purpose in life and her passion for sharing information[09:05] Living a life of gratitude in a world of abundance but not contentment[11:35] What is a peptide? What does it do to the body?[17:35] The proper way of introducing peptides to the body[21:49] A starter peptide that may work for an individual who just started to take a peptide[26:00] What is a Th1 and Th2 cell?[34:30] Utilizing both conventional and alternative medicine to provide medical solutions[38:15] Bioregulator peptides and the untapped benefits it provides to the body[43:35] Getting your hands on a peptide[50:14] Natalie relates her experience with peptides and the most profound benefits it has[56:06] The unquantifiable effects of good sleep and Nathalie's hacks for a great sleepUPGRADE YOUR WELLNESSClaim your free toxicity consult through this LINKAMD Ion Cleanse: https://calendly.com/ioncleanse/detoxCellcore - https://freddiesetgo.com/favorites/cellcore/ My favorite BindersLightPath LED https://lightpathled.com/?wpam_id=2 Discount Code - beautifullybrokenCelsius Network Website - https://celsius.network/ My Fav CRYPTO BankingBioStrap:https://biostrap.com/order-evo?ref=freddiekimmelp My Favorite Recovery Tracker Discount: BEAUTIFULLYBROKENUpgraded Formulas: LINK Code: FREDDIE10CONNECT WITH FREDDIECheck out my website and download “The Beautifully Broken Buyer's Guide” - https://freddiesetgo.com/Join my membership program -https://www.buymeacoffee.com/freddiesetgoInstagram - https://www.instagram.com/freddiesetgo/
Multiple Sclerosis (MS) is an autoimmune disorder of the Central Nervous System that has been associated with several environmental factors, such as diet and obesity. The possible link between MS and obesity has become more interesting in recent years since the discovery of the remarkable properties of adipose tissue. There is CONSTANT cell communication between immune cells, neural cells and fat (adipose) cells. The more fat cells one has on the body, the more leptin, resistin, visfatin and other hormones are released. These hormones LOWER the very important cytokine called adiponectin (a neuron protector). Also, an increase in fat cells creates an INCREASE amount of TH1 &TH17 (pro-inflammatory cytokines)n& decrease in TH2 (anti-inflammatory cytokines). More fat cells increase nitric oxide and ROS (reactive oxygen species) that causes excess cell death. ALL of this happening in the neural cells leads to a decrease in the re-myelination and increase of de-myelination. This is BAD news for a disease that is listed #1 as most common demyelinating disease of the central nervous system.
Today I'm with guest Dr Rahul Vangala This episode gets straight to the point in answering the grand question of “Why does a mother's immune system not reject a developing baby as foreign tissue?” Dr. Rahul Vangala's most interesting answer is compared to a person's rejection of organ transplants. He explains that along with the immune changes a mother experiences, the placenta's close knit anatomy is a certain immune privilege site that has the attributes of a nematode using neurokinines in order to remain “hidden” and not be detected by the host. If the host's body cannot recognize foreign substances, then it lacks the ability to enable defense mechanisms that would attack that foreign material. This is most favorable for a fetus and perpetuates gestation. He moves on to break down the complex immune responses our bodies have antigens, or foreign materials, by mentioning the main role of the TH1 T Helper Cell and it's critical function to rejecting organs. Dr. Vangala mentions this because during pregnancy it necessary that there be an ideal degree of immune suppression of TH1 responses by the presence of TH2 responses. Not only are TH1 cells suppressed but Natural Killer cells are also dampened. He then goes on to explain how the beginning stages of the placenta during implantation resembles a semi-allograft meaning that the tissues grafted in are only partially foreign. The two doctors then discuss a major topic of autoimmune disorders and the complications of attempting to get pregnant. They unveil the way the autoimmune diseases decrease the likelihood of an optimal environment for viable gestation. Although, it is not impossible for women who live with autoimmune disorders to get pregnant and deliver a health baby. However, all in all there are many adjustments to the mechanics in order to make what we see as precious miracles. #immunechanges #placenta #pregnancy #immunesystem #TCells #THelperCells #semiallograft #autoimmune #graft #host #Surrogacy #AllergyImmunology #Rashes #Hives #Hormones
This is the Morning Show that Makes you Hate All Morning Shows. Don't forget to follow https://twitter.com/https://linktr.ee/Theralphwilliam If you want a place to voice your opinions to all platforms sign up to podbean with this affiliate link https://www.podbean.com/GetCoffee Link for business hosting https://www.podbean.com/pro/GetCoffee Get some Merchandise TearzESC Shop | Redbubble Join us on Twitch! theralphwilliampodcast - Get 10% off when you use promo code RW at checkout Fromthedoctors.com Download our internet radio station in your App Store W-ESN Epic Strategies Network Epicstrategiesnetwork.com Rumble https://rumble.com/vh7g39-doggy-handling-competition.html If you are interested being apart of the discord server shoot us a DM on the social media's and joint the crew! Please Read the Rules: By calling in the show you are aware that the show will be published and that you are responsible for your own words and comments. Your opinions and commments does not reflect the views of the show. Say hello and acknowledge those in the chat when entering. Mute yourself when not talking or I will Mute You. Allow others to speak before speaking. Not a requirement but would appreciate it if you would SHARE the show Hello, My name is Spartacus, and I've had enough. We have been forced to watch America and the Free World spin into inexorable decline due to a biowarfare attack. We, along with countless others, have been victimized and gaslit by propaganda and psychological warfare operations being conducted by an unelected, unaccountable Elite against the American people and our allies. Our mental and physical health have suffered immensely over the course of the past year and a half. We have felt the sting of isolation, lockdown, masking, quarantines, and other completely nonsensical acts of healthcare theater that have done absolutely nothing to protect the health or wellbeing of the public from the ongoing COVID-19 pandemic. Now, we are watching the medical establishment inject literal poison into millions of our fellow Americans without so much as a fight. We have been told that we will be fired and denied our livelihoods if we refuse to vaccinate. This was the last straw. We have spent thousands of hours analyzing leaked footage from Wuhan, scientific papers from primary sources, as well as the paper trails left by the medical establishment. What we have discovered would shock anyone to their core. First, we will summarize our findings, and then, we will explain them in detail. References will be placed at the end. Summary: COVID-19 is a blood and blood vessel disease. SARS-CoV-2 infects the lining of human blood vessels, causing them to leak into the lungs. Current treatment protocols (e.g. invasive ventilation) are actively harmful to patients, accelerating oxidative stress and causing severe VILI (ventilator-induced lung injuries). The continued use of ventilators in the absence of any proven medical benefit constitutes mass murder. Existing countermeasures are inadequate to slow the spread of what is an aerosolized and potentially wastewater-borne virus, and constitute a form of medical theater. Various non-vaccine interventions have been suppressed by both the media and the medical establishment in favor of vaccines and expensive patented drugs. The authorities have denied the usefulness of natural immunity against COVID-19, despite the fact that natural immunity confers protection against all of the virus's proteins, and not just one. Vaccines will do more harm than good. The antigen that these vaccines are based on, SARS-CoV- 2 Spike, is a toxic protein. SARS-CoV-2 may have ADE, or antibody-dependent enhancement; current antibodies may not neutralize future strains, but instead help them infect immune cells. Also, vaccinating during a pandemic with a leaky vaccine removes the evolutionary pressure for a virus to become less lethal. There is a vast and appalling criminal conspiracy that directly links both Anthony Fauci and Moderna to the Wuhan Institute of Virology. COVID-19 vaccine researchers are directly linked to scientists involved in brain-computer interface (“neural lace”) tech, one of whom was indicted for taking grant money from China. Independent researchers have discovered mysterious nanoparticles inside the vaccines that are not supposed to be present. The entire pandemic is being used as an excuse for a vast political and economic transformation of Western society that will enrich the already rich and turn the rest of us into serfs and untouchables. COVID-19 Pathophysiology and Treatments: COVID-19 is not a viral pneumonia. It is a viral vascular endotheliitis and attacks the lining of blood vessels, particularly the small pulmonary alveolar capillaries, leading to endothelial cell activation and sloughing, coagulopathy, sepsis, pulmonary edema, and ARDS-like symptoms. This is a disease of the blood and blood vessels. The circulatory system. Any pneumonia that it causes is secondary to that. In severe cases, this leads to sepsis, blood clots, and multiple organ failure, including hypoxic and inflammatory damage to various vital organs, such as the brain, heart, liver, pancreas, kidneys, and intestines. Some of the most common laboratory findings in COVID-19 are elevated D-dimer, elevated prothrombin time, elevated C-reactive protein, neutrophilia, lymphopenia, hypocalcemia, and hyperferritinemia, essentially matching a profile of coagulopathy and immune system hyperactivation/immune cell exhaustion. COVID-19 can present as almost anything, due to the wide tropism of SARS-CoV-2 for various tissues in the body's vital organs. While its most common initial presentation is respiratory illness and flu-like symptoms, it can present as brain inflammation, gastrointestinal disease, or even heart attack or pulmonary embolism. COVID-19 is more severe in those with specific comorbidities, such as obesity, diabetes, and hypertension. This is because these conditions involve endothelial dysfunction, which renders the circulatory system more susceptible to infection and injury by this particular virus. The vast majority of COVID-19 cases are mild and do not cause significant disease. In known cases, there is something known as the 80/20 rule, where 80% of cases are mild and 20% are severe or critical. However, this ratio is only correct for known cases, not all infections. The number of actual infections is much, much higher. Consequently, the mortality and morbidity rate is lower. However, COVID-19 spreads very quickly, meaning that there are a significant number of severely-ill and critically-ill patients appearing in a short time frame. In those who have critical COVID-19-induced sepsis, hypoxia, coagulopathy, and ARDS, the most common treatments are intubation, injected corticosteroids, and blood thinners. This is not the correct treatment for COVID-19. In severe hypoxia, cellular metabolic shifts cause ATP to break down into hypoxanthine, which, upon the reintroduction of oxygen, causes xanthine oxidase to produce tons of highly damaging radicals that attack tissue. This is called ischemia-reperfusion injury, and it's why the majority of people who go on a ventilator are dying. In the mitochondria, succinate buildup due to sepsis does the same exact thing; when oxygen is reintroduced, it makes superoxide radicals. Make no mistake, intubation will kill people who have COVID-19. The end-stage of COVID-19 is severe lipid peroxidation, where fats in the body start to “rust” due to damage by oxidative stress. This drives autoimmunity. Oxidized lipids appear as foreign objects to the immune system, which recognizes and forms antibodies against OSEs, or oxidation-specific epitopes. Also, oxidized lipids feed directly into pattern recognition receptors, triggering even more inflammation and summoning even more cells of the innate immune system that release even more destructive enzymes. This is similar to the pathophysiology of Lupus. COVID-19's pathology is dominated by extreme oxidative stress and neutrophil respiratory burst, to the point where hemoglobin becomes incapable of carrying oxygen due to heme iron being stripped out of heme by hypochlorous acid. No amount of supplemental oxygen can oxygenate blood that chemically refuses to bind O2. The breakdown of the pathology is as follows: SARS-CoV-2 Spike binds to ACE2. Angiotensin Converting Enzyme 2 is an enzyme that is part of the renin-angiotensin-aldosterone system, or RAAS. The RAAS is a hormone control system that moderates fluid volume in the body and in the bloodstream (i.e. osmolarity) by controlling salt retention and excretion. This protein, ACE2, is ubiquitous in every part of the body that interfaces with the circulatory system, particularly in vascular endothelial cells and pericytes, brain astrocytes, renal tubules and podocytes, pancreatic islet cells, bile duct and intestinal epithelial cells, and the seminiferous ducts of the testis, all of which SARS-CoV-2 can infect, not just the lungs. SARS-CoV-2 infects a cell as follows: SARS-CoV-2 Spike undergoes a conformational change where the S1 trimers flip up and extend, locking onto ACE2 bound to the surface of a cell. TMPRSS2, or transmembrane protease serine 2, comes along and cuts off the heads of the Spike, exposing the S2 stalk-shaped subunit inside. The remainder of the Spike undergoes a conformational change that causes it to unfold like an extension ladder, embedding itself in the cell membrane. Then, it folds back upon itself, pulling the viral membrane and the cell membrane together. The two membranes fuse, with the virus's proteins migrating out onto the surface of the cell. The SARS-CoV-2 nucleocapsid enters the cell, disgorging its genetic material and beginning the viral replication process, hijacking the cell's own structures to produce more virus. SARS-CoV-2 Spike proteins embedded in a cell can actually cause human cells to fuse together, forming syncytia/MGCs (multinuclear giant cells). They also have other pathogenic, harmful effects. SARS-CoV- 2's viroporins, such as its Envelope protein, act as calcium ion channels, introducing calcium into infected cells. The virus suppresses the natural interferon response, resulting in delayed inflammation. SARS-CoV-2 N protein can also directly activate the NLRP3 inflammasome. Also, it suppresses the Nrf2 antioxidant pathway. The suppression of ACE2 by binding with Spike causes a buildup of bradykinin that would otherwise be broken down by ACE2. This constant calcium influx into the cells results in (or is accompanied by) noticeable hypocalcemia, or low blood calcium, especially in people with Vitamin D deficiencies and pre-existing endothelial dysfunction. Bradykinin upregulates cAMP, cGMP, COX, and Phospholipase C activity. This results in prostaglandin release and vastly increased intracellular calcium signaling, which promotes highly aggressive ROS release and ATP depletion. NADPH oxidase releases superoxide into the extracellular space. Superoxide radicals react with nitric oxide to form peroxynitrite. Peroxynitrite reacts with the tetrahydrobiopterin cofactor needed by endothelial nitric oxide synthase, destroying it and “uncoupling” the enzymes, causing nitric oxide synthase to synthesize more superoxide instead. This proceeds in a positive feedback loop until nitric oxide bioavailability in the circulatory system is depleted. Dissolved nitric oxide gas produced constantly by eNOS serves many important functions, but it is also antiviral against SARS-like coronaviruses, preventing the palmitoylation of the viral Spike protein and making it harder for it to bind to host receptors. The loss of NO allows the virus to begin replicating with impunity in the body. Those with endothelial dysfunction (i.e. hypertension, diabetes, obesity, old age, African-American race) have redox equilibrium issues to begin with, giving the virus an advantage. Due to the extreme cytokine release triggered by these processes, the body summons a great deal of neutrophils and monocyte-derived alveolar macrophages to the lungs. Cells of the innate immune system are the first-line defenders against pathogens. They work by engulfing invaders and trying to attack them with enzymes that produce powerful oxidants, like SOD and MPO. Superoxide dismutase takes superoxide and makes hydrogen peroxide, and myeloperoxidase takes hydrogen peroxide and chlorine ions and makes hypochlorous acid, which is many, many times more reactive than sodium hypochlorite bleach. Cytokine Storm Compilation: Covid-19 Vaccine Side Effects Neutrophils have a nasty trick. They can also eject these enzymes into the extracellular space, where they will continuously spit out peroxide and bleach into the bloodstream. This is called neutrophil extracellular trap formation, or, when it becomes pathogenic and counterproductive, NETosis. In severe and critical COVID-19, there is actually rather severe NETosis. Hypochlorous acid building up in the bloodstream begins to bleach the iron out of heme and compete for O2 binding sites. Red blood cells lose the ability to transport oxygen, causing the sufferer to turn blue in the face. Unliganded iron, hydrogen peroxide, and superoxide in the bloodstream undergo the Haber- Weiss and Fenton reactions, producing extremely reactive hydroxyl radicals that violently strip electrons from surrounding fats and DNA, oxidizing them severely. This condition is not unknown to medical science. The actual name for all of this is acute sepsis. We know this is happening in COVID-19 because people who have died of the disease have noticeable ferroptosis signatures in their tissues, as well as various other oxidative stress markers such as nitrotyrosine, 4-HNE, and malondialdehyde. When you intubate someone with this condition, you are setting off a free radical bomb by supplying the cells with O2. It's a catch-22, because we need oxygen to make Adenosine Triphosphate (that is, to live), but O2 is also the precursor of all these damaging radicals that lead to lipid peroxidation. The correct treatment for severe COVID-19 related sepsis is non-invasive ventilation, steroids, and antioxidant infusions. Most of the drugs repurposed for COVID-19 that show any benefit whatsoever in rescuing critically-ill COVID-19 patients are antioxidants. N-acetylcysteine, melatonin, fluvoxamine, budesonide, famotidine, cimetidine, and ranitidine are all antioxidants. Indomethacin prevents iron- driven oxidation of arachidonic acid to isoprostanes. There are powerful antioxidants such as apocynin that have not even been tested on COVID-19 patients yet which could defang neutrophils, prevent lipid peroxidation, restore endothelial health, and restore oxygenation to the tissues. Scientists who know anything about pulmonary neutrophilia, ARDS, and redox biology have known or surmised much of this since March 2020. In April 2020, Swiss scientists confirmed that COVID-19 was a vascular endotheliitis. By late 2020, experts had already concluded that COVID-19 causes a form of viral sepsis. They also know that sepsis can be effectively treated with antioxidants. None of this information is particularly new, and yet, for the most part, it has not been acted upon. Doctors continue to use damaging intubation techniques with high PEEP settings despite high lung compliance and poor oxygenation, killing an untold number of critically ill patients with medical malpractice. Because of the way they are constructed, Randomized Control Trials will never show any benefit for any antiviral against COVID-19. Not Remdesivir, not Kaletra, not HCQ, and not Ivermectin. The reason for this is simple; for the patients that they have recruited for these studies, such as Oxford's ludicrous RECOVERY study, the intervention is too late to have any positive effect. The clinical course of COVID-19 is such that by the time most people seek medical attention for hypoxia, their viral load has already tapered off to almost nothing. If someone is about 10 days post-exposure and has already been symptomatic for five days, there is hardly any virus left in their bodies, only cellular damage and derangement that has initiated a hyperinflammatory response. It is from this group that the clinical trials for antivirals have recruited, pretty much exclusively. In these trials, they give antivirals to severely ill patients who have no virus in their bodies, only a delayed hyperinflammatory response, and then absurdly claim that antivirals have no utility in treating or preventing COVID-19. These clinical trials do not recruit people who are pre-symptomatic. They do not test pre-exposure or post-exposure prophylaxis. This is like using a defibrillator to shock only flatline, and then absurdly claiming that defibrillators have no medical utility whatsoever when the patients refuse to rise from the dead. The intervention is too late. These trials for antivirals show systematic, egregious selection bias. They are providing a treatment that is futile to the specific cohort they are enrolling. India went against the instructions of the WHO and mandated the prophylactic usage of Ivermectin. They have almost completely eradicated COVID-19. The Indian Bar Association of Mumbai has brought criminal charges against WHO Chief Scientist Dr. Soumya Swaminathan for recommending against the use of Ivermectin. Ivermectin is not “horse dewormer”. Yes, it is sold in veterinary paste form as a dewormer for animals. It has also been available in pill form for humans for decades, as an antiparasitic drug. The media have disingenuously claimed that because Ivermectin is an antiparasitic drug, it has no utility as an antivirus. This is incorrect. Ivermectin has utility as an antiviral. It blocks importin, preventing nuclear import, effectively inhibiting viral access to cell nuclei. Many drugs currently on the market have multiple modes of action. Ivermectin is one such drug. It is both antiparasitic and antiviral. In Bangladesh, Ivermectin costs $1.80 for an entire 5-day course. Remdesivir, which is toxic to the liver, costs $3,120 for a 5-day course of the drug. Billions of dollars of utterly useless Remdesivir were sold to our governments on the taxpayer's dime, and it ended up being totally useless for treating hyperinflammatory COVID-19. The media has hardly even covered this at all. The opposition to the use of generic Ivermectin is not based in science. It is purely financially and politically-motivated. An effective non-vaccine intervention would jeopardize the rushed FDA approval of patented vaccines and medicines for which the pharmaceutical industry stands to rake in billions upon billions of dollars in sales on an ongoing basis. The majority of the public are scientifically illiterate and cannot grasp what any of this even means, thanks to a pathetic educational system that has miseducated them. You would be lucky to find 1 in 100 people who have even the faintest clue what any of this actually means. COVID-19 Transmission: COVID-19 is airborne. The WHO carried water for China by claiming that the virus was only droplet- borne. Our own CDC absurdly claimed that it was mostly transmitted by fomite-to-face contact, which, given its rapid spread from Wuhan to the rest of the world, would have been physically impossible. The ridiculous belief in fomite-to-face being a primary mode of transmission led to the use of surface disinfection protocols that wasted time, energy, productivity, and disinfectant. The 6-foot guidelines are absolutely useless. The minimum safe distance to protect oneself from an aerosolized virus is to be 15+ feet away from an infected person, no closer. Realistically, no public transit is safe. Surgical masks do not protect you from aerosols. The virus is too small and the filter media has too large of gaps to filter it out. They may catch respiratory droplets and keep the virus from being expelled by someone who is sick, but they do not filter a cloud of infectious aerosols if someone were to walk into said cloud. The minimum level of protection against this virus is quite literally a P100 respirator, a PAPR/CAPR, or a 40mm NATO CBRN respirator, ideally paired with a full-body tyvek or tychem suit, gloves, and booties, with all the holes and gaps taped. Live SARS-CoV-2 may potentially be detected in sewage outflows, and there may be oral-fecal transmission. During the SARS outbreak in 2003, in the Amoy Gardens incident, hundreds of people were infected by aerosolized fecal matter rising from floor drains in their apartments. COVID-19 Vaccine Dangers: The vaccines for COVID-19 are not sterilizing and do not prevent infection or transmission. They are “leaky” vaccines. This means they remove the evolutionary pressure on the virus to become less lethal. It also means that the vaccinated are perfect carriers. In other words, those who are vaccinated are a threat to the unvaccinated, not the other way around. All of the COVID-19 vaccines currently in use have undergone minimal testing, with highly accelerated clinical trials. Though they appear to limit severe illness, the long-term safety profile of these vaccines remains unknown. Some of these so-called “vaccines” utilize an untested new technology that has never been used in vaccines before. Traditional vaccines use weakened or killed virus to stimulate an immune response. The Moderna and Pfizer-BioNTech vaccines do not. They are purported to consist of an intramuscular shot containing a suspension of lipid nanoparticles filled with messenger RNA. The way they generate an immune response is by fusing with cells in a vaccine recipient's shoulder, undergoing endocytosis, releasing their mRNA cargo into those cells, and then utilizing the ribosomes in those cells to synthesize modified SARS-CoV-2 Spike proteins in-situ. These modified Spike proteins then migrate to the surface of the cell, where they are anchored in place by a transmembrane domain. The adaptive immune system detects the non-human viral protein being expressed by these cells, and then forms antibodies against that protein. This is purported to confer protection against the virus, by training the adaptive immune system to recognize and produce antibodies against the Spike on the actual virus. The J&J and AstraZeneca vaccines do something similar, but use an adenovirus vector for genetic material delivery instead of a lipid nanoparticle. These vaccines were produced or validated with the aid of fetal cell lines HEK-293 and PER.C6, which people with certain religious convictions may object strongly to. SARS-CoV-2 Spike is a highly pathogenic protein on its own. It is impossible to overstate the danger presented by introducing this protein into the human body. It is claimed by vaccine manufacturers that the vaccine remains in cells in the shoulder, and that SARS- CoV-2 Spike produced and expressed by these cells from the vaccine's genetic material is harmless and inert, thanks to the insertion of prolines in the Spike sequence to stabilize it in the prefusion conformation, preventing the Spike from becoming active and fusing with other cells. However, a pharmacokinetic study from Japan showed that the lipid nanoparticles and mRNA from the Pfizer vaccine did not stay in the shoulder, and in fact bioaccumulated in many different organs, including the reproductive organs and adrenal glands, meaning that modified Spike is being expressed quite literally all over the place. These lipid nanoparticles may trigger anaphylaxis in an unlucky few, but far more concerning is the unregulated expression of Spike in various somatic cell lines far from the injection site and the unknown consequences of that. Messenger RNA is normally consumed right after it is produced in the body, being translated into a protein by a ribosome. COVID-19 vaccine mRNA is produced outside the body, long before a ribosome translates it. In the meantime, it could accumulate damage if inadequately preserved. When a ribosome attempts to translate a damaged strand of mRNA, it can become stalled. When this happens, the ribosome becomes useless for translating proteins because it now has a piece of mRNA stuck in it, like a lace card in an old punch card reader. The whole thing has to be cleaned up and new ribosomes synthesized to replace it. In cells with low ribosome turnover, like nerve cells, this can lead to reduced protein synthesis, cytopathic effects, and neuropathies. Certain proteins, including SARS-CoV-2 Spike, have proteolytic cleavage sites that are basically like little dotted lines that say “cut here”, which attract a living organism's own proteases (essentially, molecular scissors) to cut them. There is a possibility that S1 may be proteolytically cleaved from S2, causing active S1 to float away into the bloodstream while leaving the S2 “stalk” embedded in the membrane of the cell that expressed the protein. SARS-CoV-2 Spike has a Superantigenic region (SAg), which may promote extreme inflammation. Anti-Spike antibodies were found in one study to function as autoantibodies and attack the body's own cells. Those who have been immunized with COVID-19 vaccines have developed blood clots, myocarditis, Guillain-Barre Syndrome, Bell's Palsy, and multiple sclerosis flares, indicating that the vaccine promotes autoimmune reactions against healthy tissue. SARS-CoV-2 Spike does not only bind to ACE2. It was suspected to have regions that bind to basigin, integrins, neuropilin-1, and bacterial lipopolysaccharides as well. SARS-CoV-2 Spike, on its own, can potentially bind any of these things and act as a ligand for them, triggering unspecified and likely highly inflammatory cellular activity. SARS-CoV-2 Spike contains an unusual PRRA insert that forms a furin cleavage site. Furin is a ubiquitous human protease, making this an ideal property for the Spike to have, giving it a high degree of cell tropism. No wild-type SARS-like coronaviruses related to SARS-CoV-2 possess this feature, making it highly suspicious, and perhaps a sign of human tampering. SARS-CoV-2 Spike has a prion-like domain that enhances its infectiousness. The Spike S1 RBD may bind to heparin-binding proteins and promote amyloid aggregation. In humans, this could lead to Parkinson's, Lewy Body Dementia, premature Alzheimer's, or various other neurodegenerative diseases. This is very concerning because SARS-CoV-2 S1 is capable of injuring and penetrating the blood-brain barrier and entering the brain. It is also capable of increasing the permeability of the blood-brain barrier to other molecules. SARS-CoV-2, like other betacoronaviruses, may have Dengue-like ADE, or antibody-dependent enhancement of disease. For those who aren't aware, some viruses, including betacoronaviruses, have a feature called ADE. There is also something called Original Antigenic Sin, which is the observation that the body prefers to produce antibodies based on previously-encountered strains of a virus over newly- encountered ones. In ADE, antibodies from a previous infection become non-neutralizing due to mutations in the virus's proteins. These non-neutralizing antibodies then act as trojan horses, allowing live, active virus to be pulled into macrophages through their Fc receptor pathways, allowing the virus to infect immune cells that it would not have been able to infect before. This has been known to happen with Dengue Fever; when someone gets sick with Dengue, recovers, and then contracts a different strain, they can get very, very ill. If someone is vaccinated with mRNA based on the Spike from the initial Wuhan strain of SARS-CoV-2, and then they become infected with a future, mutated strain of the virus, they may become severely ill. In other words, it is possible for vaccines to sensitize someone to disease. There is a precedent for this in recent history. Sanofi's Dengvaxia vaccine for Dengue failed because it caused immune sensitization in people whose immune systems were Dengue-naive. In mice immunized against SARS-CoV and challenged with the virus, a close relative of SARS-CoV-2, they developed immune sensitization, Th2 immunopathology, and eosinophil infiltration in their lungs. We have been told that SARS-CoV-2 mRNA vaccines cannot be integrated into the human genome, because messenger RNA cannot be turned back into DNA. This is false. There are elements in human cells called LINE-1 retrotransposons, which can indeed integrate mRNA into a human genome by endogenous reverse transcription. Because the mRNA used in the vaccines is stabilized, it hangs around in cells longer, increasing the chances for this to happen. If the gene for SARS-CoV-2 Spike is integrated into a portion of the genome that is not silent and actually expresses a protein, it is possible that people who take this vaccine may continuously express SARS-CoV-2 Spike from their somatic cells for the rest of their lives. By inoculating people with a vaccine that causes their bodies to produce Spike in-situ, they are being inoculated with a pathogenic protein. A toxin that may cause long-term inflammation, heart problems, and a raised risk of cancers. In the long-term, it may also potentially lead to premature neurodegenerative disease. Absolutely nobody should be compelled to take this vaccine under any circumstances, and in actual fact, the vaccination campaign must be stopped immediately. COVID-19 Criminal Conspiracy: The vaccine and the virus were made by the same people. In 2014, there was a moratorium on SARS gain-of-function research that lasted until 2017. This research was not halted. Instead, it was outsourced, with the federal grants being laundered through NGOs. Ralph Baric is a virologist and SARS expert at UNC Chapel Hill in North Carolina. This is who Anthony Fauci was referring to when he insisted, before Congress, that if any gain-of-function research was being conducted, it was being conducted in North Carolina. This was a lie. Anthony Fauci lied before Congress. A felony. Ralph Baric and Shi Zhengli are colleagues and have co-written papers together. Ralph Baric mentored Shi Zhengli in his gain-of-function manipulation techniques, particularly serial passage, which results in a virus that appears as if it originated naturally. In other words, deniable bioweapons. Serial passage in humanized hACE2 mice may have produced something like SARS-CoV-2. The funding for the gain-of-function research being conducted at the Wuhan Institute of Virology came from Peter Daszak. Peter Daszak runs an NGO called EcoHealth Alliance. EcoHealth Alliance received millions of dollars in grant money from the National Institutes of Health/National Institute of Allergy and Infectious Diseases (that is, Anthony Fauci), the Defense Threat Reduction Agency (part of the US Department of Defense), and the United States Agency for International Development. NIH/NIAID contributed a few million dollars, and DTRA and USAID each contributed tens of millions of dollars towards this research. Altogether, it was over a hundred million dollars. EcoHealth Alliance subcontracted these grants to the Wuhan Institute of Virology, a lab in China with a very questionable safety record and poorly trained staff, so that they could conduct gain-of-function research, not in their fancy P4 lab, but in a level-2 lab where technicians wore nothing more sophisticated than perhaps a hairnet, latex gloves, and a surgical mask, instead of the bubble suits used when working with dangerous viruses. Chinese scientists in Wuhan reported being routinely bitten and urinated on by laboratory animals. Why anyone would outsource this dangerous and delicate work to the People's Republic of China, a country infamous for industrial accidents and massive explosions that have claimed hundreds of lives, is completely beyond me, unless the aim was to start a pandemic on purpose. In November of 2019, three technicians at the Wuhan Institute of Virology developed symptoms consistent with a flu-like illness. Anthony Fauci, Peter Daszak, and Ralph Baric knew at once what had happened, because back channels exist between this laboratory and our scientists and officials. December 12th, 2019, Ralph Baric signed a Material Transfer Agreement (essentially, an NDA) to receive Coronavirus mRNA vaccine-related materials co-owned by Moderna and NIH. It wasn't until a whole month later, on January 11th, 2020, that China allegedly sent us the sequence to what would become known as SARS-CoV-2. Moderna claims, rather absurdly, that they developed a working vaccine from this sequence in under 48 hours. Stephane Bancel, the current CEO of Moderna, was formerly the CEO of bioMerieux, a French multinational corporation specializing in medical diagnostic tech, founded by one Alain Merieux. Alain Merieux was one of the individuals who was instrumental in the construction of the Wuhan Institute of Virology's P4 lab. The sequence given as the closest relative to SARS-CoV-2, RaTG13, is not a real virus. It is a forgery. It was made by entering a gene sequence by hand into a database, to create a cover story for the existence of SARS-CoV-2, which is very likely a gain-of-function chimera produced at the Wuhan Institute of Virology and was either leaked by accident or intentionally released. The animal reservoir of SARS-CoV-2 has never been found. This is not a conspiracy “theory”. It is an actual criminal conspiracy, in which people connected to the development of Moderna's mRNA-1273 are directly connected to the Wuhan Institute of Virology and their gain-of-function research by very few degrees of separation, if any. The paper trail is well- established. The lab-leak theory has been suppressed because pulling that thread leads one to inevitably conclude that there is enough circumstantial evidence to link Moderna, the NIH, the WIV, and both the vaccine and the virus's creation together. In a sane country, this would have immediately led to the world's biggest RICO and mass murder case. Anthony Fauci, Peter Daszak, Ralph Baric, Shi Zhengli, and Stephane Bancel, and their accomplices, would have been indicted and prosecuted to the fullest extent of the law. Instead, billions of our tax dollars were awarded to the perpetrators. The FBI raided Allure Medical in Shelby Township north of Detroit for billing insurance for “fraudulent COVID-19 cures”. The treatment they were using? Intravenous Vitamin C. An antioxidant. Which, as described above, is an entirely valid treatment for COVID-19-induced sepsis, and indeed, is now part of the MATH+ protocol advanced by Dr. Paul E. Marik. The FDA banned ranitidine (Zantac) due to supposed NDMA (N-nitrosodimethylamine) contamination. Ranitidine is not only an H2 blocker used as antacid, but also has a powerful antioxidant effect, scavenging hydroxyl radicals. This gives it utility in treating COVID-19. The FDA also attempted to take N-acetylcysteine, a harmless amino acid supplement and antioxidant, off the shelves, compelling Amazon to remove it from their online storefront. This leaves us with a chilling question: did the FDA knowingly suppress antioxidants useful for treating COVID-19 sepsis as part of a criminal conspiracy against the American public? The establishment is cooperating with, and facilitating, the worst criminals in human history, and are actively suppressing non-vaccine treatments and therapies in order to compel us to inject these criminals' products into our bodies. This is absolutely unacceptable. COVID-19 Vaccine Development and Links to Transhumanism: This section deals with some more speculative aspects of the pandemic and the medical and scientific establishment's reaction to it, as well as the disturbing links between scientists involved in vaccine research and scientists whose work involved merging nanotechnology with living cells. On June 9th, 2020, Charles Lieber, a Harvard nanotechnology researcher with decades of experience, was indicted by the DOJ for fraud. Charles Lieber received millions of dollars in grant money from the US Department of Defense, specifically the military think tanks DARPA, AFOSR, and ONR, as well as NIH and MITRE. His specialty is the use of silicon nanowires in lieu of patch clamp electrodes to monitor and modulate intracellular activity, something he has been working on at Harvard for the past twenty years. He was claimed to have been working on silicon nanowire batteries in China, but none of his colleagues can recall him ever having worked on battery technology in his life; all of his research deals with bionanotechnology, or the blending of nanotech with living cells. The indictment was over his collaboration with the Wuhan University of Technology. He had double- dipped, against the terms of his DOD grants, and taken money from the PRC's Thousand Talents plan, a program which the Chinese government uses to bribe Western scientists into sharing proprietary R&D information that can be exploited by the PLA for strategic advantage. Charles Lieber's own papers describe the use of silicon nanowires for brain-computer interfaces, or “neural lace” technology. His papers describe how neurons can endocytose whole silicon nanowires or parts of them, monitoring and even modulating neuronal activity. Charles Lieber was a colleague of Robert Langer. Together, along with Daniel S. Kohane, they worked on a paper describing artificial tissue scaffolds that could be implanted in a human heart to monitor its activity remotely. Robert Langer, an MIT alumnus and expert in nanotech drug delivery, is one of the co-founders of Moderna. His net worth is now $5.1 billion USD thanks to Moderna's mRNA-1273 vaccine sales. Both Charles Lieber and Robert Langer's bibliographies describe, essentially, techniques for human enhancement, i.e. transhumanism. Klaus Schwab, the founder of the World Economic Forum and the architect behind the so-called “Great Reset”, has long spoken of the “blending of biology and machinery” in his books. Since these revelations, it has come to the attention of independent researchers that the COVID-19 vaccines may contain reduced graphene oxide nanoparticles. Japanese researchers have also found unexplained contaminants in COVID-19 vaccines. Graphene oxide is an anxiolytic. It has been shown to reduce the anxiety of laboratory mice when injected into their brains. Indeed, given SARS-CoV-2 Spike's propensity to compromise the blood-brain barrier and increase its permeability, it is the perfect protein for preparing brain tissue for extravasation of nanoparticles from the bloodstream and into the brain. Graphene is also highly conductive and, in some circumstances, paramagnetic. In 2013, under the Obama administration, DARPA launched the BRAIN Initiative; BRAIN is an acronym for Brain Research Through Advancing Innovative Neurotechnologies®. This program involves the development of brain-computer interface technologies for the military, particularly non-invasive, injectable systems that cause minimal damage to brain tissue when removed. Supposedly, this technology would be used for healing wounded soldiers with traumatic brain injuries, the direct brain control of prosthetic limbs, and even new abilities such as controlling drones with one's mind. Various methods have been proposed for achieving this, including optogenetics, magnetogenetics, ultrasound, implanted electrodes, and transcranial electromagnetic stimulation. In all instances, the goal is to obtain read or read-write capability over neurons, either by stimulating and probing them, or by rendering them especially sensitive to stimulation and probing. However, the notion of the widespread use of BCI technology, such as Elon Musk's Neuralink device, raises many concerns over privacy and personal autonomy. Reading from neurons is problematic enough on its own. Wireless brain-computer interfaces may interact with current or future wireless GSM infrastructure, creating neurological data security concerns. A hacker or other malicious actor may compromise such networks to obtain people's brain data, and then exploit it for nefarious purposes. However, a device capable of writing to human neurons, not just reading from them, presents another, even more serious set of ethical concerns. A BCI that is capable of altering the contents of one's mind for innocuous purposes, such as projecting a heads-up display onto their brain's visual center or sending audio into one's auditory cortex, would also theoretically be capable of altering mood and personality, or perhaps even subjugating someone's very will, rendering them utterly obedient to authority. This technology would be a tyrant's wet dream. Imagine soldiers who would shoot their own countrymen without hesitation, or helpless serfs who are satisfied to live in literal dog kennels. BCIs could be used to unscrupulously alter perceptions of basic things such as emotions and values, changing people's thresholds of satiety, happiness, anger, disgust, and so forth. This is not inconsequential. Someone's entire regime of behaviors could be altered by a BCI, including such things as suppressing their appetite or desire for virtually anything on Maslow's Hierarchy of Needs. Anything is possible when you have direct access to someone's brain and its contents. Someone who is obese could be made to feel disgust at the sight of food. Someone who is involuntarily celibate could have their libido disabled so they don't even desire sex to begin with. Someone who is racist could be forced to feel delight over cohabiting with people of other races. Someone who is violent could be forced to be meek and submissive. These things might sound good to you if you are a tyrant, but to normal people, the idea of personal autonomy being overridden to such a degree is appalling. For the wealthy, neural laces would be an unequaled boon, giving them the opportunity to enhance their intelligence with neuroprosthetics (i.e. an “exocortex”), and to deliver irresistible commands directly into the minds of their BCI-augmented servants, even physically or sexually abusive commands that they would normally refuse. If the vaccine is a method to surreptitiously introduce an injectable BCI into millions of people without their knowledge or consent, then what we are witnessing is the rise of a tyrannical regime unlike anything ever seen before on the face of this planet, one that fully intends to strip every man, woman, and child of our free will. Our flaws are what make us human. A utopia arrived at by removing people's free will is not a utopia at all. It is a monomaniacal nightmare. Furthermore, the people who rule over us are Dark Triad types who cannot be trusted with such power. Imagine being beaten and sexually assaulted by a wealthy and powerful psychopath and being forced to smile and laugh over it because your neural lace gives you no choice but to obey your master. The Elites are forging ahead with this technology without giving people any room to question the social or ethical ramifications, or to establish regulatory frameworks that ensure that our personal agency and autonomy will not be overridden by these devices. They do this because they secretly dream of a future where they can treat you worse than an animal and you cannot even fight back. If this evil plan is allowed to continue, it will spell the end of humanity as we know it. Conclusions: The current pandemic was produced and perpetuated by the establishment, through the use of a virus engineered in a PLA-connected Chinese biowarfare laboratory, with the aid of American taxpayer dollars and French expertise. This research was conducted under the absolutely ridiculous euphemism of “gain-of-function” research, which is supposedly carried out in order to determine which viruses have the highest potential for zoonotic spillover and preemptively vaccinate or guard against them. Gain-of-function/gain-of-threat research, a.k.a. “Dual-Use Research of Concern”, or DURC, is bioweapon research by another, friendlier-sounding name, simply to avoid the taboo of calling it what it actually is. It has always been bioweapon research. The people who are conducting this research fully understand that they are taking wild pathogens that are not infectious in humans and making them more infectious, often taking grants from military think tanks encouraging them to do so. These virologists conducting this type of research are enemies of their fellow man, like pyromaniac firefighters. GOF research has never protected anyone from any pandemic. In fact, it has now started one, meaning its utility for preventing pandemics is actually negative. It should have been banned globally, and the lunatics performing it should have been put in straitjackets long ago. Either through a leak or an intentional release from the Wuhan Institute of Virology, a deadly SARS strain is now endemic across the globe, after the WHO and CDC and public officials first downplayed the risks, and then intentionally incited a panic and lockdowns that jeopardized people's health and their livelihoods. This was then used by the utterly depraved and psychopathic aristocratic class who rule over us as an excuse to coerce people into accepting an injected poison which may be a depopulation agent, a mind control/pacification agent in the form of injectable “smart dust”, or both in one. They believe they can get away with this by weaponizing the social stigma of vaccine refusal. They are incorrect. Their motives are clear and obvious to anyone who has been paying attention. These megalomaniacs have raided the pension funds of the free world. Wall Street is insolvent and has had an ongoing liquidity crisis since the end of 2019. The aim now is to exert total, full-spectrum physical, mental, and financial control over humanity before we realize just how badly we've been extorted by these maniacs. The pandemic and its response served multiple purposes for the Elite: Concealing a depression brought on by the usurious plunder of our economies conducted by rentier-capitalists and absentee owners who produce absolutely nothing of any value to society whatsoever. Instead of us having a very predictable Occupy Wall Street Part II, the Elites and their stooges got to stand up on television and paint themselves as wise and all-powerful saviors instead of the marauding cabal of despicable land pirates that they are. Destroying small businesses and eroding the middle class. Transferring trillions of dollars of wealth from the American public and into the pockets of billionaires and special interests. Engaging in insider trading, buying stock in biotech companies and shorting brick-and-mortar businesses and travel companies, with the aim of collapsing face-to-face commerce and tourism and replacing it with e-commerce and servitization. Creating a casus belli for war with China, encouraging us to attack them, wasting American lives and treasure and driving us to the brink of nuclear armageddon. Establishing technological and biosecurity frameworks for population control and technocratic- socialist “smart cities” where everyone's movements are despotically tracked, all in anticipation of widespread automation, joblessness, and food shortages, by using the false guise of a vaccine to compel cooperation. Any one of these things would constitute a vicious rape of Western society. Taken together, they beggar belief; they are a complete inversion of our most treasured values. What is the purpose of all of this? One can only speculate as to the perpetrators' motives, however, we have some theories. The Elites are trying to pull up the ladder, erase upward mobility for large segments of the population, cull political opponents and other “undesirables”, and put the remainder of humanity on a tight leash, rationing our access to certain goods and services that they have deemed “high-impact”, such as automobile use, tourism, meat consumption, and so on. Naturally, they will continue to have their own luxuries, as part of a strict caste system akin to feudalism. Why are they doing this? Simple. The Elites are Neo-Malthusians and believe that we are overpopulated and that resource depletion will collapse civilization in a matter of a few short decades. They are not necessarily incorrect in this belief. We are overpopulated, and we are consuming too many resources. However, orchestrating such a gruesome and murderous power grab in response to a looming crisis demonstrates that they have nothing but the utmost contempt for their fellow man. To those who are participating in this disgusting farce without any understanding of what they are doing, we have one word for you. Stop. You are causing irreparable harm to your country and to your fellow citizens. To those who may be reading this warning and have full knowledge and understanding of what they are doing and how it will unjustly harm millions of innocent people, we have a few more words. Damn you to hell. You will not destroy America and the Free World, and you will not have your New World Order. We will make certain of
Your immune system was meant to be in balance. When it's not, your body can't fight off chronic infections successfully. But what causes your immune system to become imbalanced? And how do we avoid those causes and keep our immune systems working for us round the clock? In a world full of conflicting medical information, Biologix Center for Optimum Health is on a mission to provide monthly, bite-sized health and wellness tips from the healing philosophy of American Biological Medicine. Our doctors at the Biologix Center are well-trained in the modalities and principles of American Biological Medicine and are eager to share their wealth of knowledge and experience putting it to practice with all those who are interested in taking their health into their own hands. This month, we're very pleased to introduce you to our very own Dr. Farney, who will be speaking on Th2 dominance and how to bring balance back to the immune system.
Listen and subscribe at www.JustProWrestlingNews.com I'm Matt Carlins and this is JUST Pro Wrestling News for Wednesday, September 15, 2021. This update is brought to you by the Wrestling Mayhem Show. Check out the new episode right now wherever you get your podcasts.. (STINGER: WWE) The launch of the rebooted NXT 2.0 saw a bunch of fresh faces...and the crowning of a new NXT Champion. Tommaso Ciampa pinned LA Knight last night to win a 4-Way for the vacant title...that also included Pete Dunne...and Von Wagner - the son of Wayne Bloom. He was added to the match after Dunne and Ridge Holland attacked Kyle O'Reilly backstage. Last night's show ended with Ciampa having a backstage staredown with another newcomer - Bron Breakker - who is the son of Rick Steiner. Breakker opened the show in an impromptu match against LA Knight, and Breakker got the win, pinning Knight with a powerslam. A new tag team debuted last night - Josh Briggs and Brooks Jensen - a recent signee, who is the son of Bull Buchanan. They lost to Imperium's Marcel Barthel & Fabian Aichner. Carmelo Hayes now has a friend watching his back - Trick Williams...and together, they beat up on Duke Hudson. Trick is Matrick Belton, a recent PC signee with a football background. Ivy Nile debuted as part of The Diamond Mine. Nile is Emily Andzulis, who was signed after she competed on NBC's The Titan Games. We got a vignette for another newcomer, Tony D'Angelo - who is Joe Ariola, a former amateur wrestling standout at the University at Buffalo. D'Angelo was shown walking the streets of Chicago and it appears he will portray a very Italian character. Hit Row's B-Fab made her NXT in-ring debut...with a win over Katrina Cortez. Mandy Rose, Gigi Dolin & Jayce Jayne beat Sarray, Kayden Carter & Kacy Catanzaro. Rose pinned Carter after a running knee strike. The wedding of Indi Hartwell and Dexter Lumis went off without a hitch. Lumis spoke on NXT TV for the very first time. (Lumis Wedding) That clip from last night's NXT. The advertised NXT Women's Title match between Raquel Gonzalez and Franky Monet did NOT happen. (STINGER: AEW) Tonight's AEW Dynamite is at the Prudential Center in Newark, New Jersey. Just added to tonight's card: Jon Moxley & Eddie Kingston vs. 2.0. Adam Cole will make his AEW in-ring debut against Frankie Kazarian. Also tonight...Darby Allin vs. Shawn Spears. Jade Cargill vs. LEGIT Leyla Hirsch. Bryan Danielson will address the AEW Champion Kenny Omega… And CM Punk will be a special guest commentator. AEW announced Tuesday that it's returning to the Chicagoland area for a live Dynamite at the Wintrust Arena on November 24th. Last night's AEW Dark...was the first with matches recorded at Universal Studios in Orlando. Orange Cassidy, Chuck Taylor & Wheeler Yuta beat Jora Johl & TH2. Cassidy pinned Johl with the Orange Punch. On last night's NWA Powerrr… Aron Stevens & Kratos beat El Rudo & Jamie Stanley to advance in the Tag Title #1 Contenders tournament. Major League Wrestling announced Bobby Fish will make his MLW debut at the Fightland show in Philadelphia on October 2nd...and Fish will be a participant in the Opera Cup tournament. Also confirmed for the Opera Cup - Lee Moriarty. Jake Atlas, who was recently released by WWE, tweeted Tuesday that he's “stepping away from wrestling completely right now” due to mental health concerns. That's JUST Pro Wrestling News for Wednesday, September 15th. Our next update comes your way tomorrow morning, so be sure to subscribe to this feed. We also thank you in advance for leaving a glowing rating or review.. I'm Matt Carlins. Thank YOU for listening. ~Full run down at www.justprowrestlingnews.com ~ • • • • • wwe #wrestling #prowrestling #smackdown #wwenetwork #wweraw #romanreigns #ajstyles #NXT #raw #njpw #wwenxt #SethRollins #TNA #johncena #RandyOrton #wrestlemania #ROH #WWF #summerslam #tripleh #aewdynamite #professionalwrestling #aew #allelitewrestling #aewontnt #DeanAmbrose #nxt #KevinOwens #wwesmackdown
Listen and subscribe at www.JustProWrestlingNews.com I'm Matt Carlins and this is JUST Pro Wrestling News for Sunday, September 5, 2021. This update is brought to you by IndyWrestling.us. (STINGER: AEW) CM Punk will wrestle for the first time in more than SEVEN years. It goes down TONIGHT at AEW's All Out pay per view. Punk will go one-on-one against Darby Allin. Kenny Omega defends the AEW Championship against Christian Cage, the only man to defeat Omega in a one-on-one match over the last two years. The Young Bucks put their AEW Tag Titles on the line against the Lucha Brothers inside a Steel Cage. Tonight could see the END of Chris Jericho's in-ring career in AEW. Those are the stakes if Jericho loses to MJF. Dr. Britt Baker defends the AEW Women's Championship against Kris Statlander. Miro defends the TNT Championship against Eddie Kingston. Plus, Jon Moxley vs. New Japan's Satoshi Kojima...Paul Wight vs. QT Marshall...and the Women's Casino Battle Royale. 20 names are announced for that match. But the lineup did change over the weekend. During a special episode of Dark on Saturday, Julia Hart was attacked backstage by Jade Cargill and Nyla Rose. Hart was ruled unable to compete and pulled from the Battle Royale. Her replacement will be Skye Blue. Tony Khan made that announcement after Blue lost to Red Velvet on Dark. Anyway, that leaves ONE entrant still a mystery heading into Sunday. The Buy In pre-show has Jurassic Express & the Best Friends trio of Orange Cassidy, Chuck Taylor & Wheeler Yuta vs. the Hardy Family Office's Matt Hardy alongside Private Party & TH2.. (STINGER: New Japan) New Japan is at the MetLife Dome in Saitama on Sunday for its second Wrestle Grand Slam show of the weekend. On Saturday's show… Hiroshi Tanahashi pinned Kota Ibushi to retain the IWGP United States Championship. Bullet Club has a new member. SHO joined the group after he used a steel chair to defeat YOH. SHO is now part of Bullet Club sub-faction with EVIL, Dick Togo and Yujiro Takehashi called the House Of Torture. Jeff Cobb pinned Kazuchika Okada with the Tour Of The Islands. Toru Yano reclaimed the 2021 KOPW trophy by forcing Chase Owens to say “I Quit”. Jr Champ Robbie Eagles & Tiger Mask beat Hiromu Takahashi & BUSHI. Eagles submitted BUSHI. Saya Kamitani & Momo Watanabe beat Maika & Lady C. Kamitani pinned Lady C with a Phoenix Splash. New Japan announced that January's Wrestle Kingdom will be a THREE night event. Two nights in Tokyo Dome on January 4th & 5th. The third night will be at Yokohama Arena on January 8th. (STINGER: WWE) The new-look NXT will make its debut in September 14th. Former TNA color commentator Don West announced Saturday that his cancer is in remission. That's JUST Pro Wrestling News for Sunday, September 5th. Our next update comes your way tomorrow morning, so be sure to subscribe to this feed. We also thank you in advance for leaving a glowing rating or review.. I'm Matt Carlins. Thank YOU for listening. ~Full run down at www.justprowrestlingnews.com ~ • • • • • wwe #wrestling #prowrestling #smackdown #wwenetwork #wweraw #romanreigns #ajstyles #NXT #raw #njpw #wwenxt #SethRollins #TNA #johncena #RandyOrton #wrestlemania #ROH #WWF #summerslam #tripleh #aewdynamite #professionalwrestling #aew #allelitewrestling #aewontnt #DeanAmbrose #nxt #KevinOwens #wwesmackdown
Listen and subscribe at www.JustProWrestlingNews.com I'm Matt Carlins and this is JUST Pro Wrestling News for Tuesday, August 24, 2021. A special welcome to those of you listening on OccupyProWrestling.com. If you want to bring our updates to your website...email us: desk@justprowrestlingnews.com. (STINGER: WWE) Tonight's NXT will have the first fallout from TakeOver 36… PLUS, the finals of the NXT Breakout Tournament: Carmelo Hayes vs. Odyssey Jones...Timothy Thatcher vs. Ridge Holland...and Hit Row vs. Legado Del Fantasma. Last night's Raw put a number of storylines into motion...leading to three pretty big matches being announced for next week. The Miz ambushed John Morrison, putting an end to their partnership. Those two men will meet in a match on next week's Raw. The breakup went down after Xavier Woods beat Miz. Morrison tried to spray Woods with a drip-stick...but got Miz instead. Doudrop formally cut ties with Eva Marie - although she's keeping the name for some reason. Eva attacked Doudrop backstage to seal the split. Those two are also set for a match on next week's Raw. Last night's show opened with the NEW United States Champion Damian Priest confronting WWE Champion Bobby Lashley. That eventually led to Priest & Drew McIntyre taking on Lashley & Sheamus. Lashley walked out on his partner...and Sheamus was pinned after a Claymore from McIntyre. So, Lashley will face Sheamus in a non-title match on next week's Raw. The celebration for the NEW Raw Women's Champion Charlotte Flair was interrupted by Alexa Bliss...but she only wanted to say “Hi”. As for the former champ, Nikki A.S.H. tagged with Rhea Ripley and beat Nia Jax & Shayna Baszler. Ripley pinned Baszler with the Riptide. Riddle pinned AJ Styles with Bro Derek to win last night's main event. Also, Karrion Kross - with some snazzy new entrance gear - beat Ricochet. Some details are emerging about the frustrating problems for the live fans in attendance at Allegiant Stadium in Las Vegas for SummerSlam. At one point during the show, the stadium's cashless payment system went down, leaving fans unable to buy ANY concessions. This was part of a nationwide outage to the credit card processor TSYS. PetCo Park, the home of the San Diego Padres, was also affected. (STINGER: AEW) An indoor mask mandate will be in effect for all three shows AEW is running at the Now Arena outside Chicago...culminating in the All Out pay per view. The order covering all of Cook County, Illinois went into effect on Monday...in response to an increase in COVID-19 cases. Dissension in Dark Order! Colt Cabana, Alan “5” Angels & Evil Uno lost to Death Triangle in the main event of last night's AEW Dark: Elevation. A reversal late in the match led to Uno delivering a forearm strike to Angels...and Angels later took the pin. After the match, Uno was clearly upset at Angels. Cabana and the rest of Dark Order had to step in to cool off the situation. No rest for Angels. He's back in action TONIGHT on Dark...against Dante Martin. Also on tonight's Dark…Orange Cassidy, Chuck Taylor & Wheeler Yuta vs. Matt Hardy & TH2. Cassidy, Taylor & Yuta beat TH2 & The Blade on last night's Elevation. Cassidy pinned The Blade. (STINGER: New Japan) New Japan is running four straight days at Korakuen Hall starting Tuesday. IWGP World Heavyweight Champion Shingo Takagi and BUSHI are NOT on any of the cards after they tested positive for COVID-19 last week. Neither are six other wrestlers pulled from shows last week due to their contact with Takagi and BUSHI: Tetsuya Naito, SANADA, EVIL, Yujiro Takahashi, Gedo, and Dick Togo. This week's shows will feature the debuts of two NEW Young Lions. Kosei Fujita and Ryohei Oiwa. They'll face one another on all four shows this week. (STINGER: ROH) Two women are now in the semifinals of Ring Of Honor's women's title tournament. On this past weekend's ROH TV, Rok-C beat Quinn McKay...and Miranda Alize beat Nicole Savoy. The main event saw DEMONIC Flamita beat Rey Horus in a No Disqualification Match. That's JUST Pro Wrestling News for Tuesday, August 24. Our next update comes your way tomorrow morning, so be sure to subscribe to this feed. We also thank you in advance for leaving a glowing rating or review.. I'm Matt Carlins. Thank YOU for listening. ~Full run down at www.justprowrestlingnews.com ~ • • • • • wwe #wrestling #prowrestling #smackdown #wwenetwork #wweraw #romanreigns #ajstyles #NXT #raw #njpw #wwenxt #SethRollins #TNA #johncena #RandyOrton #wrestlemania #ROH #WWF #summerslam #tripleh #aewdynamite #professionalwrestling #aew #allelitewrestling #aewontnt #DeanAmbrose #nxt #KevinOwens #wwesmackdown
Hydrogen's role in the energy transition has gained popularity as new use cases (and markets) open up, but concerns around distribution and storage have affected its real-world applications. Jared Moore joins us this week to discuss the potential for the hydrogen economy and the challenges it faces. Hydrogen is an energy carrier, not an energy source, and can deliver or store a tremendous amount of energy. Hydrogen can be used in fuel cells to generate electricity, or power, and heat.Recommended reading for hydrogen as an energy carrierGuest Bio: Jared Moore is an independent energy consultant and Founder of TH2 Motors, a forerunner of the Thermal Hydrogen economy that will manufacture Solid Oxide Fuel Cell (SOFC) range extenders for electric vehicles, enabling the *option* to charge via the grid or fuel cells which are rapidly refueled at conventional gas stations. Jared earned his Ph.D. in Engineering and Public Policy from Carnegie Mellon University and has worked as independent energy consulting since 2014 from Washington, D.C., providing technical policy analysis focusing on electricity markets and the interaction between energy sectors. His peer-reviewed paper "Hourly modeling of Thermal Hydrogen electricity markets" was recently awarded "Paper of the Year" by Clean Energy journal.Learn more about TH2 MotorsConnect with Jared on LinkedInSupport the podcast on PatreonSubscribe to our newsletter
Välkommen till vårt andra avsnitt där vi bjudit in Docent Jenny Mjösberg från Karolinska Institutet för att diskutera ILC2-cellernas roll vid Typ 2-inflammation.Länk till diskuterade artiklar: Gurram et al. 2019. Orchestration between ILC2s and Th2 cells in shaping type 2 immune responsesMeininger et al. 2020. Tissue-Specific Features of Innate Lymphoid CellsVid synpunkter, förslag på samtalsämnen eller frågor kan ni skriva till oss på enkvartomtyp2@sanofi.com MAT-SE-2100512 (V.1.0) April 2021
Is it the host or the bug that is most important? The worse thing you can do is weaken the immune system when there is a pandemic. H1N1 changed its glycoprotein spike arrangement in 1915. In 1918 , it was called the Spanish Flu and killed 675,000 Americans and 100 million Worldwide! But the human immune system adapted and fought back. In June 2009 H1N1 changed a bit again and killed 13,000 Americans. I personally was very worried about H1N1 (still am). Its nastier than most. H1N1 still causes 90% of all FluA outbreaks and infections today! But the human immune system adapted and fought back. Herd immunity as a group, better Th1 & Th2 and Killer T cells as an individual put us back on top of the food chain. Natural selection rocking us on! Dr. Fred Clary, founder of Functional Analysis Chiropractic Technique and lifting and life coach and gym chalk covered philosopher opens a conversation on the history of a pandemic. Prayers and positive thoughts to all those affected physically, emotionally, economically and spiritually by the current crisis!
Using Spore-Based Probiotics (Sporebiotics) to Improve Your Health - Live Podcast #157 Get Show Updates Here: http://www.beyondwellnessradio.com/newsletter Show Transcription: https://justinhealth.com/sporebiotics-to-improve-your-health-live-podcast-157/ You-tube Podcast Subscribe: http://www.youtube.com/subscription_center?add_user=justinhealth In this podcast, Dr. Justin Marchegiani and Evan Brand digs deep into the topic of probiotics, or more specifically, spore-based probiotics (sporebiotics). Basically, the cell wall of these bacteria which is the spore is known for having awesome benefits of modulating the immune system. One of the benefits of probiotics or sporebiotics is the way it combats the negative effects of electromagnetic fields (EMFs). We may not beware of it, but constant exposure to EMF can actually increase the virulence of infections, parasites, and inflammation in the body, which is why we always try to boost the good bacteria in our system so we could counteract this negative effect. Also, learn about bacillus spores and how it prevents immune system problems like allergies, etc. For more information about the effects of spore-based probiotics, kindly watch this podcast. In this episode, we cover: 03:00 EMF's and Infections 06:29 L. Gasseri and Histamine 09:16 Th1, Th2 immune system and vaccines 18:55 Paleo template and bowel irregularity 24:48 Lectins Subscribe on I-Tunes: http://www.beyondwellnessradio.com/itunes Review us at: http://www.beyondwellnessradio.com/itunes Visit us at: http://www.beyondwellnessradio.com Have a question: http://www.beyondwellnessradio.com/question References: https://justinhealth.com/products/megasporbiotic/ https://justinhealth.com/products/probio-flora/ https://www.topochicousa.net/ https://www.drberg.com/blog/the-truth-on-vaccines
Dr. Anne O'Garra talks about the 1997 work of Zheng and Flavell on the role of GATA-3 in Th2 cytokine gene expression in CD4 T cells.
Natural ways to strengthen your immune system – Podcast #66 Get Show Updates Here: http://www.beyondwellnessradio.com/newsletter Get the show transcripts here: http://justinhealth.com/natural-ways-to-strengthen-your-immune-system-podcast-66/ Dr. Justin Marchegiani and Evan Brand talk about the various natural ways we can do and supplements we can take to help boost our immune system, especially when we're experiencing an acute illness. Find out about what you can do to enhance your immune system and stay away from illnesses. There are a lot of techniques that you'll learn about how you can supercharge your immune system in this podcast. Dr. Justin breaks down the different branches of the immune system to help us better understand how it works. Learn about what Vitamins A, C, and D, zinc, and silver can do for the immune system as well as what medicinal mushrooms and adaptogenic herbs can do to help. In this episode, topics include: 5:28 foundational info for immune health 11:48 Th1, Th2, IgA, IgG, and IgM 14:16 herbs to boost immune system 17:34 flu viruses and the flu vaccine, symptoms and viruses 24:40 nutrients and vitamins Write us a review: http://www.beyondwellnessradio.com/itunes Visit us at: http://www.beyondwellnessradio.com Have a question: http://www.beyondwellnessradio.com/question
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