Podcasts about APL

  • 494PODCASTS
  • 1,007EPISODES
  • 39mAVG DURATION
  • 5WEEKLY NEW EPISODES
  • Nov 6, 2025LATEST

POPULARITY

20172018201920202021202220232024

Categories



Best podcasts about APL

Show all podcasts related to apl

Latest podcast episodes about APL

Zināmais nezināmajā
Mistērijas, baisais un bailīgais - kāpēc tas mūs uzrunā?

Zināmais nezināmajā

Play Episode Listen Later Nov 6, 2025 50:41


Cilvēkus visos laikos saistījuši baisi stāsti, kriminālās ziņas un viss mīklainais un neatklātais. Vai tās būtu kādas paranormālas parādībās, detektīvs vai šausmu filma - tie visi rada aizrautību un zināmu devu adrenalīna. Kāpēc cilvēki labprāt izvēlas baidīties un kāpēc mūs saista nezināmais? Ko par to stāsta folkloras un psiholoģijas pētījumi? Raidījumā Zināmais nezināmajā sarunājas Latvijas Universitātes Humanitāro zinātņu fakultātes pētnieks Ingus Barovskis un psihoterapeits, RSU Psihosomatikās medicīnas un psihoterapijas katedras docents Artūrs Utināns. Par spokiem runājot, kāpēc mēs dažkārt baidāmies no izdomātiem tēliem, nevis no reālām dzīves situācijām un problēmām, piemēram, slikta dzīvesveida, ka tas radīt gan slimības vai izraisīt pat nāvi. Kāpēc iedomu spoks dažkārt nobiedē vairāk nekā neveselīgs dzīvesveids? Artūrs Utināns: Tas ir smadzeņu evolūcijas likums, bioloģiskā evolūcija ir konservatīvāka par kulturālo evolūciju. Tāpēc, piemēram, var pajautāt, kāpēc cilvēki baidās no zirnekļa? Ja būs 20 sieviešu auditorija, vismaz vienai noteikti būs zirnekļa fobija. Vēl kādai varētu būt čūsku vai peļu fobija. Es 32 prakses gados ne reizi neesmu nevienu cilvēku redzējis, kam būtu pistoļu fobija, piemēram. Šī zirnekļu, čūsku, peļu, žurku fobija - tā ir dispozīcija no mūsu evolucionārās pagātnes, kad mēs izgājām no Āfrikas, un šie dzīvnieki bija bīstami vai peles un žurkas pārnēsāja kaut kādas slimības. Līdz ar to tie cilvēki, kas turējās vairāk pa gabalu, tie labāk izdzīvoja. Lai arī mūsu smadzenēm nebija patiesā skaidrojuma, kāpēc tāda maza, pelēka pelīte varētu būt bīstama.  Savukārt tas, kas nāk ar kultūru, piemēram, holesterīna līmenis un glikozes līmenis asinīs, to mūsu smadzenes tā neasimilē. Nav tā, ka mūsu zemapziņā konkrēti zirneklis ierakstās kā fobiskais objekts, bet dispozīcija, ka vieni objekti izsauc bailes vieglāk un fobijas, savukārt tie citi jaunie kulturālie - mazāk. Tāpat kā cilvēki automašīnās iet bojā daudz biežāk nekā lidmašīnu katastrofās, bet fobija lidot vai fobija no augstuma mums kā pērtiķu turpinātājiem, kas lēkāja pa kokiem un varēja nokrist no zara, ir aktuālāka, nekā iedomāties, ka automašīna ir daudz bīstamāka. Vai līdzīgi ir mainījies tas, par ko mītiskajos stāstos vai mistērijās un filmās mēģina mums šīs bailes radīt. Mūs vairs nenobiedēs ar kaut ko, ar ko varēja nobiedēt varbūt cilvēku pirms simts un 1000 gadiem. Ingus Barovskis: Man jau pat gribas jautāt: ar ko vispār vēl var nobiedēt mūsdienu cilvēku? Vai tad mēs visu jau neesam redzējuši? Zombijs ir redzēts, pele jau arī ir redzēta... Rakstniekam Vladimiram Kaijakam gan 70. gadu beigās iznāca stāsts "Zirneklis", kur arī biedē ar zirnekli, kurš kļūst milzīgi liels un līdzīgi kā amerikāņu filmās mēdz ieturēties ar cilvēku.  Protams, tas baiļu objekts, respektīvi, tas objekts, kuram būtu jāizraisa bailes, mainās līdz ar kultūras periodiem. Tas mainās arī ar to aspektu, kurš piedāvā šo baiļu objektu. Ja paskatāmies senākās kristietības idejās - kas ir ellē? Kārtīgam cilvēkam ir jābaidās no elles. Tad ir visnotaļ krāšņi aprakstīti tie radījumi, kas cilvēku tur sagaidīs, velni, dēmoni un tā tālāk. Neviens negrib tur nonākt un sastapties ar šiem radījumiem. Un gluži vienkārši cilvēks dara to, lai tas nenotiktu. Pamatā, protams, ir ticība. Manuprāt, ja mēs neticam kaut kam, mēs nebaidāmies. Ja mēs neticam spokiem, diez vai mēs iedomāsimies, ka tas, kas uzmirdzēja kaut kur pagriezienā, ka tas ir spoks. Tāpat, ja skatāmies latviešu mitoloģijas kontekstā - baidās no tā, kas ir svarīgs, baidās no tā, kas ir arī nozīmīgs. Piemēram, zeme, htoniskais. Kāpēc baidīties no htoniskā? Čūska ir htoniskā būtne, saistīta ar lielo pirmmāti, ar atdzimšanu. Ko tur baidīties? Bet baidās no tā, kas svarīgs un pret kuru kaut kā ne tā izturoties, var kaitēt. Ja izdara kaut ko ne tā, kā vajag, var nebūt raža, var nebūt auglība. Tāpēc tas rada bailes.  Ko dara maza pelīte, kāpēc baidīties? Pele nonāk pazemē, viņa ir kā mediators, šeit, protams, runāju no mitoloģiskā skatījuma, viņa ir kā mediators starp šo pasauli un pazemes pasauli. Un tas jau uzreiz ir diezgan bīstami. Iespējams, tas kaut kā vēl joprojām reprezentējas cilvēka domāšanā, cilvēka uzskatos. Es šobrīd filozofēju. Raidījumā noslēgumā zinātnes ziņas Lai neraudātu, sīpolu iesaka griezt ar asu nazi, bet lēnām Iepsējams beidzot rasts risinājums, kā raudāt mazāk, griežot sīpolus. Tā kā pie vainas ir sīpolu sulā esošā viela - kāds sērorganisko savienojumu klases oksīds, zinātnieki no Cornela universitātes ASV izmērījuši, ka, griežot sīpolus ar asiem nažiem un lēnākām kustībām, tā sulā esošās attiecīgās vielas molekulas izplatās lēnāk un mazākā apjomā, tā pasargājot acis no asarošanas. Aplūkojot sīpolu griešanu augstas izšķirtspējas mikroskopā, pētnieki secinājuši, ka, griežot sīpolus ar asākiem nažiem, tiek pielikts mazāk spēka to mizu saspiešanai, kā rezultātā sīpolos esošās sulas pilieni gaisā izplatās mazāk un līdz acīm nemaz nenonāk. Zinātnieki rada “superkoksni”, kas ir stiprāka par tēraudu Šāda vēsts, kas publicēta “CNN” tīmekļa vietnē, nonākusi mūsu uzmanības lokā šonedēļ. Tiesa, “superkoksnes” pētījumi aizsākušies jau agrāk, tos īstenojis materiālzinātnieks, Jeilas Universitātes profesors Liangbings Hu. Pirms vairāk nekā desmit gadiem viņš uzsācis meklējumus, kā inovatīvi pārveidot koksni, bet galvenais mērķis - padarīt koksni stiprāku. 2017. gadā viņa darbībā noticis izrāviens, kas pēc tam aprakstīts publikācijā vietnē “Nature”. Profesors Hu koksni vispirms vārījis ūdens vannā ar izvēlētām ķīmiskām vielām, pēc tam koksni karsti presējis, lai to padarītu ievērojami blīvāku. Nedēļu ilgā procesa beigās iegūtajai koksnei stiprības un svara attiecība bijusi “augstāka nekā lielākajai daļai strukturālo metālu un sakausējumu”. Tā savulaik teikts publikācijā “Nature”, un šobrīd “superkoksne” tiek piedāvāta komerciālai ražošanai.  Cik sens ir šis “superkoksnes” stāsts globālā un Latvijas kontekstā? Kas pašmāju zinātniekiem, kuri ikdienā strādā ar koksnes pētījumiem, koksnes blīvināšanu un lignīna noņemšanas procesiem šķiet jau pazīstams un kas ir jauns? Stāsta Latvijas Valsts koksnes ķīmijas institūta Celulozes laboratorijas vadošā pētniece Laura Andže.

Innovation Now
Beyond a Concept

Innovation Now

Play Episode Listen Later Nov 4, 2025


Dragonfly has moved far beyond a concept on a computer screen.

For Vuck's Sake
S11 Ep5 - Vs Perth Glory

For Vuck's Sake

Play Episode Listen Later Nov 4, 2025 33:30


The Vuck register their first win of the season against a very poor Perth Glory. The line-up changes had a positive impact which included a great performance from Juan Mata. Will this result create the momentum we need leading into the derby? Follow us on Twitter, Instagram & FacebookSupport us on PatreonMON THE VUCK

radio-immo.fr, l'information immobilière
Budget 2026 : « Quand on touche aux APL, on s'en prend à la République », alerte Louis Boyard, député (LFI) du Val-de-Marne - A la Une des Quatre Colonnes

radio-immo.fr, l'information immobilière

Play Episode Listen Later Oct 31, 2025 7:43


Après le rapport parlementaire publié avant l'été de deux députés macronistes Thomas Cazenave et Charles Sitzenstuhl qui proposait de conditionner les aides au logement des étudiants aux revenus parentaux et de revoir ainsi le calcul de l'aide personnalisée au logement (APL), la suppression pour les étudiants étrangers fait déjà bondir les locataires et leurs propriétaires mais aussi les fédérations et les associations comme l'Union sociale de l'habitat (USH), la Fondation pour le logement des défavorisés. A l'occasion du premier conseil des ministres du Gouvernement Lecornu le 14 octobre 2025, l'article 67 du projet de loi de finances pour 2026 prévoit que les aides ne seront pas revalorisées pour suivre le rythme de l'inflation en 2026 comme prévu par l'année blanche et annoncée par l'ancien Premier ministre François Bayrou. D'après le texte introduit dans le PLF, « le maintien des APL à leur niveau de 2025 permettra de réaliser une économie de 108 millions d'euros pour l'État. » Pour la Fondation pour le logement des défavorisés, « cette mesure est discriminante et injuste. » Sur environ 320 000 étudiants extracommunautaires, une minorité seulement de 2 % sont éligibles aux bourses sur les critères sociaux. De son côté, le Gouvernement a d'ores-et-déjà confirmé ses intentions. « Quand un Français va étudier aux États-Unis ou en Chine, il n'a droit à rien. À l'heure où des efforts sont demandés aux Français, chacun peut comprendre cette mesure », a expliqué ces jours-ci la porte-parole du gouvernement dans Le Parisien .

Podcasts sur radio-immo.fr
Budget 2026 : « Quand on touche aux APL, on s'en prend à la République », alerte Louis Boyard, député (LFI) du Val-de-Marne - A la Une des Quatre Colonnes

Podcasts sur radio-immo.fr

Play Episode Listen Later Oct 31, 2025 7:43


Après le rapport parlementaire publié avant l'été de deux députés macronistes Thomas Cazenave et Charles Sitzenstuhl qui proposait de conditionner les aides au logement des étudiants aux revenus parentaux et de revoir ainsi le calcul de l'aide personnalisée au logement (APL), la suppression pour les étudiants étrangers fait déjà bondir les locataires et leurs propriétaires mais aussi les fédérations et les associations comme l'Union sociale de l'habitat (USH), la Fondation pour le logement des défavorisés. A l'occasion du premier conseil des ministres du Gouvernement Lecornu le 14 octobre 2025, l'article 67 du projet de loi de finances pour 2026 prévoit que les aides ne seront pas revalorisées pour suivre le rythme de l'inflation en 2026 comme prévu par l'année blanche et annoncée par l'ancien Premier ministre François Bayrou. D'après le texte introduit dans le PLF, « le maintien des APL à leur niveau de 2025 permettra de réaliser une économie de 108 millions d'euros pour l'État. » Pour la Fondation pour le logement des défavorisés, « cette mesure est discriminante et injuste. » Sur environ 320 000 étudiants extracommunautaires, une minorité seulement de 2 % sont éligibles aux bourses sur les critères sociaux. De son côté, le Gouvernement a d'ores-et-déjà confirmé ses intentions. « Quand un Français va étudier aux États-Unis ou en Chine, il n'a droit à rien. À l'heure où des efforts sont demandés aux Français, chacun peut comprendre cette mesure », a expliqué ces jours-ci la porte-parole du gouvernement dans Le Parisien .

逐工一幅天文圖 APOD Taigi
1419. 暗暝 ê 冥王星 ft. 阿錕 (20251002)

逐工一幅天文圖 APOD Taigi

Play Episode Listen Later Oct 28, 2025 2:08


這个烏影景色 就是冥王星暗暝彼半爿。遮是一个暗淡 koh 遙遠 ê 世界。這張予人讚嘆 ê 太空視角內底,太陽 to̍h tī 49 億公里遠(差不多是 4.5 光時遠)ê 所在。這張相片是 飛足遠 ê 新視野號太空船 tī 2015 年 7 月 翕 ê。彼陣 ê 太空船離冥王星 2 萬 1 千公里遠,差不多是伊 ùi 離冥王星 上近彼位飛--出去 ê 19 分鐘後。這个 Kuiper 帶 ê 成員有戲劇性 ê 外形。Ùi 這張相片來看,咱知影冥王星 霧霧 ê 大氣層其實是蔫蔫,而且實在是 有夠複雜 ê。Tī 這張相片頂懸彼个月眉形 ê 晨昏區景色 內底,有南部地區 ê 窒素冰原,這馬叫做 Sputnik 平原,嘛有 坎坎坷坷、有水冰 ê Norgay 山脈。 ——— 這是 NASA Astronomy Picture of the Day ê 台語文 podcast 原文版:https://apod.nasa.gov/ 台文版:https://apod.tw/ 今仔日 ê 文章: https://apod.tw/daily/20251002/ 影像:NASA, Johns Hopkins Univ./APL, Southwest Research Institute 音樂:P!SCO - 鼎鼎 聲優:阿錕 翻譯:An-Li Tsai (TARA) 原文:https://apod.nasa.gov/apod/ap251002.html Powered by Firstory Hosting

Radio Marija Latvija
Pāvesta vēstījums 2025. gada Misiju dienai | Dienas katehēze | Bīskaps Andris Kravalis | Aija Avotiņa | 21.10.2025.

Radio Marija Latvija

Play Episode Listen Later Oct 22, 2025 54:28


Aplūkojam pāvesta vēstījumu 2025. gada Misiju dienai.

For Vuck's Sake
S11 Ep3 - Vs Auckland FC

For Vuck's Sake

Play Episode Listen Later Oct 21, 2025 38:23


The Vuck open the new season with a 0-0 against Auckland FC. With a few injuries to the best XI it was a reasonable result but one that didn't ease the concerns around our strikers. Follow us on Twitter, Instagram & FacebookSupport us on PatreonMON THE VUCK

Chez Kevin Razy
#127 CHEZ KEVIN RAZY : Marine inéligible, Franc-Tireur, Lecornu taxe la France

Chez Kevin Razy

Play Episode Listen Later Oct 17, 2025 97:01


Bienvenue dans le 127ème épisode de "Chez Kevin Razy". Deux fois par semaine, on se retrouve ici pour parler de ce qui se passe dans la vie comme dans un groupe WhatsApp. On ne s'interdit aucun sujet.Pour soutenir notre podcast :https://fr.tipeee.com/ckr-podcast/Rejoins notre canal Telegram :https://t.me/CKRnews▬▬▬▬▬▬ DANS CET EPISODE ▬▬▬▬▬▬▬Cette semaine, on revient sur :

Susto
Hallo-Weird Special!

Susto

Play Episode Listen Later Oct 16, 2025 43:42 Transcription Available


Thank you Austin Public Library for always giving the ghouls a scary good time! Please enjoy this collection of stories from attendee's at APL's Hallo-Weird event!La Casa de Los TubosThis Fall Season's eventsWant to hear your story on Susto? Fill out the Letters From the Beyond form or visit SustoPodcast.com to be shared on the show!Become a Patron here! Subscribe to Susto's YouTube channel!

For Vuck's Sake
S11 Ep2 - Season Preview

For Vuck's Sake

Play Episode Listen Later Oct 14, 2025 51:19


What's this? Another episode so soon? This time its our season preview. We go over the Vuck squad and address some of the burning questions the off season has raised. We sprinkle in some predictions and look toward the opening round fixture against Auckland. Follow us on Twitter, Instagram & FacebookSupport us on PatreonMON THE VUCK

For Vuck's Sake
S11 Ep1 - Off Season Wrap

For Vuck's Sake

Play Episode Listen Later Oct 12, 2025 75:56


After the world's longest off-season FVS is back! We blow off the cobwebs and get out on the track for an off-season wrap where we take a look at all the ins and outs, as well as give our correct take on the new kits. Follow us on Twitter, Instagram & FacebookSupport us on PatreonMON THE VUCK

Elitefts Table Talk podcast
#373 Peaking is a F*cking Waste of Time" - A World-Class Coach Explains | Thomas Lilley

Elitefts Table Talk podcast

Play Episode Listen Later Oct 10, 2025 169:07


We welcome Thomas Lilley to this episode of Dave Tate's Table Talk Podcast! Thomas is a 36-year-old Australian powerlifting coach, gym owner, and federation president who founded Zero Weakness, a powerhouse strength brand with 11 gyms across Australia, New Zealand, and the UK. He leads three major federations—APL, NZPU, and UKPU—with APL now Australia's largest. Known for coaching lifters to multiple all-time world records, including the #1 total of 1200kg (wraps) and highest DOTs score ever (688.33), Thomas also holds the #1 equipped total and bench in Australia. Through ZeroW's expansion into franchising, education, and equipment, and his work on the Peak Speak and ZeroW Podcasts, Thomas continues to shape global powerlifting culture. Instagram: https://www.instagram.com/tombro7/Youtube: https://www.youtube.com/ptcgoldcoast Zero W: https://www.zerowequipment.com/   Become an elitefts channel member for early access to Dave Tate's Table Talk podcast and other perks. ➡️@eliteftsofficial Support Dave Tate's Table Talk: FULL Crew Access - https://www.elitefts.com/join-the-crew Limited Edition Apparel - https://www.elitefts.com/shop/apparel/limited-edition.html Programs & More - https://www.elitefts.com/shop/dave-tate-s-table-talk-crew.html TYAO Application - https://www.elitefts.com/dave-tate-s-tyao-application Best-selling elitefts Products: Pro Resistance Training Bands: https://www.elitefts.com/shop/bands.html Specialty Barbells: https://www.elitefts.com/shop/bars-weights/specialty-bars.html Wraps, Straps, Sleeves: https://www.elitefts.com/shop/power-gear.html Sponsors: Get an extra 10% OFF at elitefts (CODE: TABLE TALK): https://www.elitefts.com/ Get 10% OFF Your Next Marek Health Labs (CODE: TABLETALK): https://marekhealth.com/ Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors: https://partners.drinklmnt.com/free-g... Get 10% OFF at Granite Nutrition (CODE TABLETALK): https://granitenutrition.com/?utm_sou... Support Massenomics! https://www.massenomics.com/ Save 20% on monthly, yearly, or lifetime MASS Research Review (CODE ELITEFTS20): https://massresearchreview.com/ Get 10% OFF RP Hypertrophy App (CODE: TABLE TALK) :https://go.rpstrength.com/hypertrophy...

Remnant Finance
E68 - Non-Forfeiture Options: Safety Nets, Not a Strategy

Remnant Finance

Play Episode Listen Later Oct 10, 2025 58:56


What happens if you can't afford your whole life insurance premium anymore? It's the most common concern when people design large policies for Infinite Banking: "I don't want to pay this huge premium until I'm 95 years old." The truth is, once you understand what premium is doing for you—building momentum, creating guaranteed growth, and establishing your family banking system—you won't want to stop. But life happens. Income disruptions, career changes, or simply changing priorities might make you reconsider. That's why understanding your contractual rights matters. There are five distinct options when you can't or won't continue paying premiums, and most people only know about the worst one: surrendering for cash. This episode breaks down all five options, from the contractual non-forfeiture provisions required by state law to the optimal strategy that lets your policy sustain itself. We explain extended term insurance, reduced paid-up insurance, automatic premium loans, and the dividend payment strategy—plus why working with an authorized IBC practitioner ensures you actually have access to these options. The goal isn't to plan your exit from day one, but to understand the full contract you're entering and know you have control no matter what happens.Chapters:00:00 - Opening segment07:00 - Introduction to non-forfeiture options and PUA  10:00 - Four contractual non-forfeiture options overview  11:20 - Cash value refresher13:00 - Net present value14:40 - Dave Ramsey's misrepresentation   17:50 - Company exposure and why cash value grows over time  18:55 - Option 1: Cash surrender value (closing the policy)  20:30 - Option 2: Extended term insurance explained  25:45 - Option 3: Automatic premium loan (APL)  27:00 - When APL makes sense: income disruption scenarios  32:00 - Base premium vs. total premium: What you actually need to sustain  35:00 - Option 4: Reduced paid-up insurance (RPU)  36:25 - Why you can't RPU before year seven (MEC rules)  42:15 - How using dividends changes projections  44:50 - Option 5: Using dividends to pay premiums (the optimal strategy)  48:05 - Keeping premium door open  52:00 - Protection and savings before speculation  54:10 - Keeping the wall between savings and investments  56:30 - Final thoughtsKey Takeaways:- Cash surrender value is not separate from death benefit—it's your equity in the future payment at present value- There are 5 total options when you can't pay premium: 4 contractual non-forfeiture options plus the dividend strategy- Cash surrender (Option 1): Walk away with equity, lose all coverage—least recommended option- Extended term insurance (Option 2): Same death benefit dollar amount, reduced timeframe based on cash value- Reduced paid-up insurance (Option 3): Same timeframe (whole life), reduced death benefit, no future premiums required- Automatic premium loan (Option 4): Company loans against cash value to pay base premium automatically- Dividend payment (Option 5): Use policy dividends to pay base premium—the optimal approach for mature policies- Not all whole life companies support optimal IBC design—must have PUA riders available- Work only with Nelson Nash Institute authorized practitioners to ensure proper policy structure- Goal is never to stop paying premium once you understand what it's doing for your family banking system- Your whole life policy should be the asset you understand most completely before signingGot Questions?Reach out to us at info@remnantfinance.com or book a call at https://remnantfinance.com/calendar !Visit https://remnantfinance.com for more informationLow Stress Trading: https://remnantfinance.com/options  FOLLOW REMNANT FINANCEYoutube: @RemnantFinance (https://www.youtube.com/@RemnantFinance )Facebook: @remnantfinance (https://www.facebook.com/profile.id=61560694316588 )Twitter: @remnantfinance (https://x.com/remnantfinance )TikTok: @RemnantFinanceDon't forget to hit LIKE and SUBSCRIBE

The Advisor Lab
Episode 176 Future Proof Conversations: Cheryl Nash

The Advisor Lab

Play Episode Listen Later Oct 9, 2025 9:35


We sat down with Cheryl Nash, President of APL at InvestCloud, on the boardwalk at Future Proof Festival to discuss the current landscape of retail investing. APL is a portfolio management platform that powers construction, modeling, trading, and rebalancing for managed accounts. Cheryl shares how APL democratizes access to private market strategies and enables the private wealth channel to invest in alternatives.

Kodsnack in English
Kodsnack 658 - Failure of ergonomics, with Taylor Troesh

Kodsnack in English

Play Episode Listen Later Sep 2, 2025 46:14


Fredrik talks to Taylor Troesh about packaging things, generating code, and database evolution. Why is it so hard to package and build things? Is it a failure of ergonomics? Is there hope for a change? We also discuss generating code using LLMs, and Taylor presents the workflow of using them to generate projects from scratch, starting over if more fundamental changes are needed. After that, we dig into databases and SQL, and Taylor has many thoughts and opinions about how they can be used and might evolve. Finally, we discuss other interesting projects, keeping track of ideas, what the OPTC is, and why should you cut down a palm tree? Recorded during Øredev 2024. The episode is sponsored by Ellipsis - let us edit your podcast and make it sound just as good as Kodsnack! With more than ten years and 1200 episodes of experience, Ellipsis gets your podcast edited, chapterized, and described with all related links in a prompt and professional manner. Thank you Cloudnet for sponsoring our VPS! Comments, questions or tips? We a re @kodsnack, @tobiashieta, @oferlund and @bjoreman on Twitter, have a page on Facebook and can be emailed at info@kodsnack.se if you want to write longer. We read everything we receive. If you enjoy Kodsnack we would love a review in iTunes! You can also support the podcast by buying us a coffee (or two!) through Ko-fi. Links Taylor Taylor’s keyboard-rich desk setup Taylor’s Øredev 2024 talk: How to flatpack programs The IKEA hacking community (or one of them) James Mickens Redux The flux architecture Jquery Toki pona APL Zig SNOBOL Actor model Jq Lisp Scrapscript - Taylor’s own language HTMX CRUD Elm Support us on Ko-fi Cursor Neovim Avante - a Cursor alternative for Neovim Sam Altman Sam Colt Sam Morse Postgresql Connecting directly to the database - Svante Richter’s talk Supabase SQL Some of Taylor’s writings about SQL PRQL - Pipelined relational query language FQL Regex Foundationdb Ellipsis - sponsor of the week: we edit Kodsnack, and we can edit your podcast too! Offensive horticulture A history of microwave ovens Scrapsheets Game of life Trailer buses Follow-up links, thanks to unvisual: Bruck - “a type of bus or coach built to combine goods and passenger transport” Skvader - a Swedish bruck The timeless way of software - Taylor talks about Christopher Alexander, just like we did in episode 657! Titles Nothing besides IKEA I did not besmirch the reputation How strange we package things I don’t think I have any advice Failure of ergonomics I do have hope Drinking from the well Brainless CRUD-stuff (I have) No qualms with Elm During the binges Fifteen math professors Tilting against palmtrees OPTC

Fonction Publique Mon Amour
Innover dans la fonction publique : à quel prix ? avec Sabine Marini

Fonction Publique Mon Amour

Play Episode Listen Later Aug 28, 2025 26:37


On célèbre souvent les initiatives internes à l'État comme des signes d'agilité ou de transformation. Mais que se passe-t-il lorsqu'un agent public, sans quitter sa mission, décide de porter un projet innovant de bout en bout ? Cet épisode donne la parole à Sabine Marini, fonctionnaire à la DDTM des Bouches-du-Rhône, qui a mené pendant quatre ans un projet d'intrapreneuriat. Une démarche fondée sur le sens du service et l'intelligence du terrain. Cet échange offre un regard sincère sur les marges de manœuvre – et les limites – de l'innovation dans la fonction publique.Fonctionnaire depuis plusieurs années, Sabine Marini travaille aujourd'hui à la DDTM des Bouches-du-Rhône. Entre 2021 et 2024, elle a été intrapreneure publique sur le projet APiLos : le portail du conventionnement APL. Un engagement parallèle à son poste, mené sans rémunération supplémentaire, et qui interroge les conditions réelles de reconnaissance dans la fonction publique.https://www.fonctionpubliquemonamour.fr/0227Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

The Other A.I
Beyond the Buzz: The Rise of Alcohol-Free Spirits

The Other A.I

Play Episode Listen Later Aug 19, 2025 53:00


On this episode, Pauline explores the fast-growing world of alcohol-free wines and spirits with two industry leaders: Emily Onkey, co-founder and CMO of Aplós, and Vanessa Kay, former CMO of Moët Hennessy USA and now a board member at Aplós. Together, they unpack the Aplós story — from its inspiration and brand identity to its marketing strategy and future prospects. They also delve into the rise of the “sober-curious” movement and discuss why consumers are rethinking their relationship with alcohol, how this shift is transforming the beverage industry, and, more broadly, how it's redefining the way people socialize and celebrate.

Estoicismo Filosofia
10 HABITOS ESTOICOS PARA SER FELIZ | ESTOICISMO

Estoicismo Filosofia

Play Episode Listen Later Aug 16, 2025 13:06


✨ Apoya nuestro podcast y disfruta sin interrupciones ✨ Si valoras nuestro contenido, ayúdanos a seguir creando más episodios y, como agradecimiento, escucha Estoicismo Filosofía Premium sin anuncios.

Cleveland's Morning News with Wills and Snyder
Cleveland APL - Furry Friend 8-14-25 - Tank

Cleveland's Morning News with Wills and Snyder

Play Episode Listen Later Aug 14, 2025 1:33


Tank - Dog - 4 yr old Pittie Mix - Came to APL at the beginning of June through Humane Investigations after not being provided the Vet care he needed - He received the care he needed at the APL and is still looking for his new family.

Estoicismo Filosofia
PIENSA y ACTÚA como las PERSONAS ABUNDANTES y EXITOSAS - SABIDURÍA ESTOICA

Estoicismo Filosofia

Play Episode Listen Later Aug 14, 2025 41:43


✨ Apoya nuestro podcast y disfruta sin interrupciones ✨ Si valoras nuestro contenido, ayúdanos a seguir creando más episodios y, como agradecimiento, escucha Estoicismo Filosofía Premium sin anuncios.

The Startup CPG Podcast
#208 - Fundraising Reflections with David Fudge (Aplós) and Amanda Amos (Collaborative Fund)

The Startup CPG Podcast

Play Episode Listen Later Aug 5, 2025 73:11


In this episode of the Startup CPG Podcast, host Daniel Scharff speaks with David Fudge, Co-Founder and CEO of Aplós, and Amanda Amos, Investor at Collaborative Fund, for a comprehensive discussion on the current fundraising landscape in consumer packaged goods.Together, they break down what has — and hasn't — changed in the early-stage fundraising environment, with actionable advice for founders from both an operator's and investor's perspective. Amanda shares how Collaborative Fund evaluates startups, what investors look for in pitch decks, how to think about market size, and the importance of aligning with the right capital partners. David offers hard-earned insights from building Aplós, including how he navigated early fundraising, how his pitch evolved over time, and what advice he gives to other founders stepping into the fundraising arena.They also discuss bootstrapping vs. raising venture capital, SAFE notes vs. priced rounds, how to build authentic investor relationships, and the real expectations around valuation and ownership.Whether you're a founder preparing to raise or just curious about how the process works behind the scenes, this episode is packed with practical wisdom and candid reflections.

L'info en intégrale - Europe 1
Le journal de 7h30 du 15/07/2025

L'info en intégrale - Europe 1

Play Episode Listen Later Jul 15, 2025 7:53


Dans cette édition :Le Premier ministre François Bayrou doit dévoiler cet après-midi les grandes lignes de ses orientations budgétaires, avec notamment la possibilité d'une année blanche, de la désindexation des retraites sur l'inflation et de la réduction des prestations sociales comme les APL.La proposition de la députée LFI Mathilde Panot de désarmer la police municipale se heurte à la réalité du terrain, avec de nombreuses villes, y compris de gauche, choisissant au contraire d'équiper leurs policiers municipaux d'armes à feu, comme à Annonay en Ardèche.Le MEDEF a proposé une batterie de mesures pour mettre les comptes de l'assurance maladie à l'équilibre, comme la simplification du calcul des indemnités journalières ou l'instauration de jours de carence non pris en charge par la Sécurité sociale.La ministre de l'Éducation nationale Elisabeth Borne a recadré son collègue Philippe Baptiste, ministre de l'Enseignement supérieur, qui avait affirmé que l'islamo-gauchisme n'existait pas, l'accusant d'être responsable de la montée de cette idéologie.Notre équipe a utilisé un outil d'Intelligence artificielle via les technologies d'Audiomeans© pour accompagner la création de ce contenu écrit.Distribué par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Le journal - Europe 1
Le journal de 7h30 du 15/07/2025

Le journal - Europe 1

Play Episode Listen Later Jul 15, 2025 7:53


Dans cette édition :Le Premier ministre François Bayrou doit dévoiler cet après-midi les grandes lignes de ses orientations budgétaires, avec notamment la possibilité d'une année blanche, de la désindexation des retraites sur l'inflation et de la réduction des prestations sociales comme les APL.La proposition de la députée LFI Mathilde Panot de désarmer la police municipale se heurte à la réalité du terrain, avec de nombreuses villes, y compris de gauche, choisissant au contraire d'équiper leurs policiers municipaux d'armes à feu, comme à Annonay en Ardèche.Le MEDEF a proposé une batterie de mesures pour mettre les comptes de l'assurance maladie à l'équilibre, comme la simplification du calcul des indemnités journalières ou l'instauration de jours de carence non pris en charge par la Sécurité sociale.La ministre de l'Éducation nationale Elisabeth Borne a recadré son collègue Philippe Baptiste, ministre de l'Enseignement supérieur, qui avait affirmé que l'islamo-gauchisme n'existait pas, l'accusant d'être responsable de la montée de cette idéologie.Notre équipe a utilisé un outil d'Intelligence artificielle via les technologies d'Audiomeans© pour accompagner la création de ce contenu écrit.Distribué par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

ITmedia Mobile
60倍ズームに対応したスマホ向け望遠レンズ「APL 20-60X」、Makuakeで先行販売

ITmedia Mobile

Play Episode Listen Later Jul 14, 2025 0:22


60倍ズームに対応したスマホ向け望遠レンズ「APL 20-60X」、Makuakeで先行販売。 Smart Sellingは、7月14日にスマートフォン向け望遠レンズ「APL 20-60X」を応援購入サービス「Makuake」で先行販売開始した。プロジェクト期間は7月30日まで。

radio-immo.fr, l'information immobilière
Projet de loi de finances 2026 : « J'ai déjà le profond sentiment que le budget de l'hébergement d'urgence ne sera pas touché ! », affirme François Jolivet, député de l'Indre et rapporteur du budget logement - A la Une des Quatre Colonnes

radio-immo.fr, l'information immobilière

Play Episode Listen Later Jul 11, 2025 12:43


À quelques jours du discours du Premier ministre François Bayrou tant attendu devant la presse le 15 juillet 2025, Matignon et Bercy font tout pour brouiller les pistes. Pour le moment, rien ne filtre à l'Assemblée nationale dans la salle des Quatre colonnes sur le sort du logement et sur les sujets prioritaires comme l'hébergement d'urgence, la réduction de loyer de solidarité (RLS), MaPrimeRenov' ou encore le PTZ . Au moment où les étudiants viennent de terminer leurs épreuves d'écrit du Baccalauréat, les parlementaires et notamment ceux de la Chambre haute planchent eux ardemment pour présenter une copie et présenter quelques préconisations pour redresser les finances publiques et trouver 40 à 50 milliards d'euros d'économies pour ramener le déficit à 4,6 %. D'autres pistes sont sur la table comme celle de la mise en place de la TVA sociale comme levier de financement de la protection sociale. Questionné par Radio.Immo, à l'issue de la commission des Finances, ce mercredi 9 juillet 2025, le député de l'Indre (Circonscription de Châteauroux, 52 000 habitants) François Jolivet, proche d'Édouard Philippe (groupe politique Horizons) alerte de nouveau sur la crise du logement. Le vice-président de la commission et rapporteur du logement à l'Assemblée nationale depuis huit ans après son premier rapport du PLF 2018 et spécialiste du sujet de la réforme des APL a la ferme conviction sur les prévisions du projet de loi de finances 2026 que « le budget de l'hébergement d'urgence ne sera pas touché. » La question majeure ? « C'est surtout de savoir quel sort sera donné au statut du bailleur privé concocté par Marc-Philippe Daubresse et Mickaël Cosson », confie le parlementaire dans la salle des Quatre Colonnes. C'est une opération qui vise à reconduire à l'identique certaines dépenses de l'Etat, sans tenir compte de l'inflation. Pour Henry- Buzy Cazaux, président de l'IMSI et tout récemment décoré de l'Ordre national du mérite par le Premier ministre à l'hôtel Matignon : « Que cela soit logement d'urgence, RLS, MaPrimeRenov' et la continuité du PTZ, ce sont des priorités marquées dans le marbre et sur ce qu'il sera très difficile de transiger. Par contre sur le statut du bailleur privé, on lui cherche des poux et la négociation sera plus fragile avec Bercy

PyBites Podcast
#195: Patterns, paradigms, and pythonic thinking with Rodrigo Girão Serrão

PyBites Podcast

Play Episode Listen Later Jul 8, 2025 51:00 Transcription Available


In this ep, we chat with Rodrigo Girão Serrão about his journey from mathematician to Pythonista. What started as a colleague's tip turned into 11 years of Python exploration. Rodrigo shares how his background in APL reshaped the way he writes Python, helping him embrace list comprehensions and functional patterns more intuitively.We dig into his latest side project—a bytecode compiler written in Python—and what that reveals about how Python really works under the hood. Rodrigo unpacks dunder methods, decorators, and how Python's consistent design makes building elegant, expressive code a joy.He also shares great advice on giving talks: from deep diving into topics to letting ideas evolve before structuring a presentation. His love for community and clarity in coding is contagious.Whether you're new to Python or a seasoned dev, this conversation will give you a deeper appreciation for the language we all love.Connect with Rodrigo on socials:Github: https://github.com/rodrigogiraoserraoLinkedIn: https://www.linkedin.com/in/rodrigo-gir%C3%A3o-serr%C3%A3o/Check our these links for some further reading/viewing:RP podcast: https://realpython.com/podcasts/rpp/252/The categorisation of the module itertools: https://mathspp.com/blog/module-itertools-overviewA tutorial on decorators: https://mathspp.com/blog/pydonts/decoratorsAn article about dunder methods: https://mathspp.com/blog/pydonts/dunder-methodsWhy APL is a language worth knowing (article): https://mathspp.com/blog/why-apl-is-a-language-worth-knowingHow APL made me a better Python developer (talk/video): https://www.youtube.com/watch?v=tDy-to9fgawThe series of articles with the compiler/interpreter: https://mathspp.com/blog/tags/bpciA tutorial is not a long talk: https://mathspp.com/blog/a-tutorial-is-not-a-long-talkHow I prepare a technical talk: https://mathspp.com/blog/how-i-prepare-a-technical-talk Structural pattern matching: https://peps.python.org/pep-0636/ ___

Salvador Mingo -Conocimiento Experto-
¿Por qué no avanzas? Nadie te habló del verdadero lenguaje del subconsciente

Salvador Mingo -Conocimiento Experto-

Play Episode Listen Later Jul 7, 2025 10:01


¿Por qué repetir afirmaciones no funciona? Porque tu subconsciente no escucha lo que dices… siente lo que sientes. En este video te revelo un método olvidado, silenciado por la medicina formal y redescubierto por la neurociencia moderna. Un método simple, efectivo y profundamente transformador que puedes aplicar cada mañana entre las 4:00 y las 6:00 a.m. Aprende a reprogramar tu mente desde el cuerpo, no desde el intelecto. Aplícalo durante 7 días y comparte en los comentarios qué descubriste. Explora más herramientas de transformación en: Guías y recursos: https://conocimientoexperto.com/accede-a-las-guias Podcast Oficial: https://open.spotify.com/show/65J8RTsruRXBxeQElVmU0b Instagram: https://www.instagram.com/salvadormingo/ Comparte este contenido con quien busca algo más que motivación momentánea. ✒ Salvador Mingo Creador de Conocimiento Experto #ReprogramaTuMente #Subconsciente #Autosugestión #DesarrolloPersonalReal #SalvadorMingo #ConocimientoExperto #Neuroplasticidad #4AMMindset

Conocimiento Experto
¿Por qué no avanzas? Nadie te habló del verdadero lenguaje del subconsciente

Conocimiento Experto

Play Episode Listen Later Jul 7, 2025 10:02


¿Por qué repetir afirmaciones no funciona? Porque tu subconsciente no escucha lo que dices… siente lo que sientes. En este video te revelo un método olvidado, silenciado por la medicina formal y redescubierto por la neurociencia moderna. Un método simple, efectivo y profundamente transformador que puedes aplicar cada mañana entre las 4:00 y las 6:00 a.m. Aprende a reprogramar tu mente desde el cuerpo, no desde el intelecto. Aplícalo durante 7 días y comparte en los comentarios qué descubriste. Explora más herramientas de transformación en: Guías y recursos: https://conocimientoexperto.com/accede-a-las-guias Podcast Oficial: https://open.spotify.com/show/65J8RTsruRXBxeQElVmU0b Instagram: https://www.instagram.com/salvadormingo/ Comparte este contenido con quien busca algo más que motivación momentánea. ✒ Salvador Mingo Creador de Conocimiento Experto #ReprogramaTuMente #Subconsciente #Autosugestión #DesarrolloPersonalReal #SalvadorMingo #ConocimientoExperto #Neuroplasticidad #4AMMindsetConviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/conocimiento-experto--2975003/support.

YORDI EN EXA
Técnicas Japonesas

YORDI EN EXA

Play Episode Listen Later Jul 3, 2025 8:39


Platicamos de algunas técnicas japonesas que les recomendamos a todas esas personas que te necesitan un respiro del mundo real y no están pudiendo salir de vacaciones. ¡Aplícalas! See omnystudio.com/listener for privacy information.

WiseNuts Podcast
EP0330 Martin Melkonian | LA Protests Erupt, Antifa Infiltration & Israel-Iran War Escalates

WiseNuts Podcast

Play Episode Listen Later Jun 17, 2025 126:25


We're LIVE tonight breaking down two major stories making headlines with Special Guest Martin Melkonian.

The Story of a Brand
Aplós - If a Fashion Brand Made a Spirit

The Story of a Brand

Play Episode Listen Later May 28, 2025 62:28


When Rose Hamilton, Founder of Compass Rose Ventures, first tried Aplós, she knew there was something different, sophisticated, calming, and beautifully intentional.  In this episode, Rose sits down with David Fudge, Co-founder and CEO of Aplós, to unpack how he's not just building a brand—he's reimagining what it means to unwind. From Bonobos to beverage, David's journey is a masterclass in blending creative vision with operational strategy. We dive deep into how Aplós is breaking category codes while anchoring to timeless consumer desires. David shares how his fashion-forward, design-driven mindset helped shape a non-alcoholic spirit brand that's as emotionally resonant as it is operationally sound.  Whether you're a founder, marketer, or brand strategist, this episode is full of insights that will have you rethinking what brand-building really means today. Here are a few key moments to listen for: * How David leveraged a non-beverage background to challenge industry norms—and why not knowing the rules can be an asset. * The concept of “disciplined disruption”: choosing which category codes to break and which to honor. * Why bartenders—not just consumers—are key to Aplós's advocacy and growth strategy. * Building a go-to-market strategy rooted in both aspiration and data: from DTC learnings to luxury retail partnerships. * David's powerful mantra: “Be convicted in vision, malleable in strategy,” and what it means for modern founders navigating fast-changing landscapes. Join us in listening to the episode to discover how David is crafting more than a product. He's creating a cultural shift in how we gather, relax, and connect. This is a story of vision, values, and the bold art of brand building. For more on Aplós, visit:  https://www.aplos.world/ If you enjoyed this episode, please leave The Story of a Brand Show a rating and review.  Plus, don't forget to follow us on Apple and Spotify.  Your support helps us bring you more content like this! * Today's Sponsors: Compass Rose Ventures - Advisor for CPG Brands: https://compassroseventures.com/contact/ Compass Rose Ventures can help your CPG brand increase customer lifetime value, expand into the US market, create an omnipresent omnichannel footprint, optimize customer journeys, build brand communities, and more. Visit the link above to learn more.      Workspace6 - Private Community for 7, 8, 9-figure Brands: https://www.workspace6.io/ Workspace6 is a private community where over 950 seven, eight, and nine-figure brand operators trade insights, solve problems, and shortcut growth. It's the anti-fluff operator's room, and for your first 30 days, it's just $1. Get real answers and skip the trial and error

Cancer Stories: The Art of Oncology
An Oncologist's Guide to Ensuring Your First Medical Grand Rounds Will Be Your Last: Lessons on How NOT to Induce Coma in Your Audience

Cancer Stories: The Art of Oncology

Play Episode Listen Later May 13, 2025 27:23


Listen to ASCO's JCO Oncology Practice, Art of Oncology Practice article, "An Oncologist's Guide to Ensuring Your First Medical Grand Rounds Will Be Your Last” by Dr. David Johnson, who is a clinical oncologist at University of Texas Southwestern Medical School. The article is followed by an interview with Johnson and host Dr. Mikkael Sekeres. Through humor and irony, Johnson critiques how overspecialization and poor presentation practices have eroded what was once internal medicine's premier educational forum. Transcript Narrator: An Oncologist's Guide to Ensuring Your First Medical Grand Rounds Will Be Your Last, by David H. Johnson, MD, MACP, FASCO   Over the past five decades, I have attended hundreds of medical conferences—some insightful and illuminating, others tedious and forgettable. Among these countless gatherings, Medical Grand Rounds (MGRs) has always held a special place. Originally conceived as a forum for discussing complex clinical cases, emerging research, and best practices in patient care, MGRs served as a unifying platform for clinicians across all specialties, along with medical students, residents, and other health care professionals. Expert speakers—whether esteemed faculty or distinguished guests—would discuss challenging cases, using them as a springboard to explore the latest advances in diagnosis and treatment. During my early years as a medical student, resident, and junior faculty member, Grand Rounds consistently attracted large, engaged audiences. However, as medicine became increasingly subspecialized, attendance began to wane. Lectures grew more technically intricate, often straying from broad clinical relevance. The patient-centered discussions that once brought together diverse medical professionals gradually gave way to hyperspecialized presentations. Subspecialists, once eager to share their insights with the wider medical community, increasingly withdrew to their own specialty-specific conferences, further fragmenting the exchange of knowledge across disciplines. As a former Chair of Internal Medicine and a veteran of numerous MGRs, I observed firsthand how these sessions shifted from dynamic educational exchanges to highly specialized, often impenetrable discussions. One of the most striking trends in recent years has been the decline in presentation quality at MGR—even among local and visiting world-renowned experts. While these speakers are often brilliant clinicians and investigators, they can also be remarkably poor lecturers, delivering some of the most uninspiring talks I have encountered. Their presentations are so consistently lackluster that one might suspect an underlying strategy at play—an unspoken method to ensure that they are never invited back. Having observed this pattern repeatedly, I am convinced that these speakers must be adhering to a set of unwritten rules to avoid future MGR presentations. To assist those unfamiliar with this apparent strategy, I have distilled the key principles that, when followed correctly, all but guarantee that a presenter will not be asked to give another MGR lecture—thus sparing them the burden of preparing one in the future. Drawing on my experience as an oncologist, I illustrate these principles using an oncology-based example although I suspect similar rules apply across other subspecialties. It will be up to my colleagues in cardiology, endocrinology, rheumatology, and beyond to identify and document their own versions—tasks for which I claim no expertise. What follows are the seven “Rules for Presenting a Bad Medical Oncology Medical Grand Rounds.” 1.  Microscopic Mayhem: Always begin with an excruciatingly detailed breakdown of the tumor's histology and molecular markers, emphasizing how these have evolved over the years (eg, PAP v prostate-specific antigen)—except, of course, when they have not (eg, estrogen receptor, progesterone receptor, etc). These nuances, while of limited relevance to general internists or most subspecialists (aside from oncologists), are guaranteed to induce eye-glazing boredom and quiet despair among your audience. 2. TNM Torture: Next, cover every nuance of the newest staging system … this is always a real crowd pleaser. For illustrative purposes, show a TNM chart in the smallest possible font. It is particularly helpful if you provide a lengthy review of previous versions of the staging system and painstakingly cover each and every change in the system. Importantly, this activity will allow you to disavow the relevance of all previous literature studies to which you will subsequently refer during the course of your presentation … to wit—“these data are based on the OLD staging system and therefore may not pertain …” This phrase is pure gold—use it often if you can. NB: You will know you have “captured” your audience if you observe audience members “shifting in their seats” … it occurs almost every time … but if you have failed to “move” the audience … by all means, continue reading … there is more! 3. Mechanism of Action Meltdown: Discuss in detail every drug ever used to treat the cancer under discussion; this works best if you also give a detailed description of each drug's mechanism of action (MOA). General internists and subspecialists just LOVE hearing a detailed discussion of the drug's MOA … especially if it is not at all relevant to the objectives of your talk. At this point, if you observe a wave of slack-jawed faces slowly slumping toward their desktops, you will know you are on your way to successfully crushing your audience's collective spirit. Keep going—you are almost there. 4. Dosage Deadlock: One must discuss “dose response” … there is absolutely nothing like a dose response presentation to a group of internists to induce cries of anguish. A wonderful example of how one might weave this into a lecture to generalists or a mixed audience of subspecialists is to discuss details that ONLY an oncologist would care about—such as the need to dose escalate imatinib in GIST patients with exon 9 mutations as compared with those with exon 11 mutations. This is a definite winner! 5. Criteria Catatonia: Do not forget to discuss the newest computed tomography or positron emission tomography criteria for determining response … especially if you plan to discuss an obscure malignancy that even oncologists rarely encounter (eg, esthesioneuroblastoma). Should you plan to discuss a common disease you can ensure ennui only if you will spend extra time discussing RECIST criteria. Now if you do this well, some audience members may begin fashioning their breakfast burritos into projectiles—each one aimed squarely at YOU. Be brave … soldier on! 6. Kaplan-Meier Killer: Make sure to discuss the arcane details of multiple negative phase II and III trials pertaining to the cancer under discussion. It is best to show several inconsequential and hard-to-read Kaplan-Meier plots. To make sure that you do a bad job, divide this portion of your presentation into two sections … one focused on adjuvant treatment; the second part should consist of a long boring soliloquy on the management of metastatic disease. Provide detailed information of little interest even to the most ardent fan of the disease you are discussing. This alone will almost certainly ensure that you will never, ever be asked to give Medicine Grand Rounds again. 7. Lymph Node Lobotomy: For the coup de grâce, be sure to include an exhaustive discussion of the latest surgical techniques, down to the precise number of lymph nodes required for an “adequate dissection.” To be fair, such details can be invaluable in specialized settings like a tumor board, where they send subspecialists into rapturous delight. But in the context of MGR—where the audience spans multiple disciplines—it will almost certainly induce a stultifying torpor. If dullness were an art, this would be its masterpiece—capable of lulling even the most caffeinated minds into a stupor. If you have carefully followed the above set of rules, at this point, some members of the audience should be banging their heads against the nearest hard surface. If you then hear a loud THUD … and you're still standing … you will know you have succeeded in giving the world's worst Medical Grand Rounds!   Final Thoughts I hope that these rules shed light on what makes for a truly dreadful oncology MGR presentation—which, by inverse reasoning, might just serve as a blueprint for an excellent one. At its best, an outstanding lecture defies expectations. One of the most memorable MGRs I have attended, for instance, was on prostaglandin function—not a subject typically associated with edge-of-your-seat suspense. Given by a biochemist and physician from another subspecialty, it could have easily devolved into a labyrinth of enzymatic pathways and chemical structures. Instead, the speaker took a different approach: rather than focusing on biochemical minutiae, he illustrated how prostaglandins influence nearly every major physiologic system—modulating inflammation, regulating cardiovascular function, protecting the gut, aiding reproduction, supporting renal function, and even influencing the nervous system—without a single slide depicting the prostaglandin structure. The result? A room full of clinicians—not biochemists—walked away with a far richer understanding of how prostaglandins affect their daily practice. What is even more remarkable is that the talk's clarity did not just inform—it sparked new collaborations that shaped years of NIH-funded research. Now that was an MGR masterpiece. At its core, effective scientific communication boils down to three deceptively simple principles: understanding your audience, focusing on relevance, and making complex information accessible.2 The best MGRs do not drown the audience in details, but rather illuminate why those details matter. A great lecture is not about showing how much you know, but about ensuring your audience leaves knowing something they didn't before. For those who prefer the structured wisdom of a written guide over the ramblings of a curmudgeon, an excellent review of these principles—complete with a handy checklist—is available.2 But fair warning: if you follow these principles, you may find yourself invited back to present another stellar MGRs. Perish the thought! Dr. Mikkael SekeresHello and welcome to JCO's Cancer Stories: The Art of Oncology, which features essays and personal reflections from authors exploring their experience in the oncology field. I'm your host, Mikkael Sekeres. I'm Professor of Medicine and Chief of the Division of Hematology at the Sylvester Comprehensive Cancer Center, University of Miami.  What a pleasure it is today to be joined by Dr. David Johnson, clinical oncologist at the University of Texas Southwestern Medical School. In this episode, we will be discussing his Art of Oncology Practice article, "An Oncologist's Guide to Ensuring Your First Medical Grand Rounds Will Be Your Last."  Our guest's disclosures will be linked in the transcript.  David, welcome to our podcast and thanks so much for joining us. Dr. David JohnsonGreat to be here, Mikkael. Thanks for inviting me. Dr. Mikkael SekeresI was wondering if we could start with just- give us a sense about you. Can you tell us about yourself? Where are you from? And walk us through your career. Dr. David JohnsonSure. I grew up in a small rural community in Northwest Georgia about 30 miles south of Chattanooga, Tennessee, in the Appalachian Mountains. I met my wife in kindergarten. Dr. Mikkael SekeresOh my. Dr. David JohnsonThere are laws in Georgia. We didn't get married till the third grade. But we dated in high school and got married after college. And so we've literally been with one another my entire life, our entire lives. Dr. Mikkael SekeresMy word. Dr. David JohnsonI went to medical school in Georgia. I did my training in multiple sites, including my oncology training at Vanderbilt, where I completed my training. I spent the next 30 years there, where I had a wonderful career. Got an opportunity to be a Division Chief and a Deputy Director of, and the founder of, a cancer center there. And in 2010, I was recruited to UT Southwestern as the Chairman of Medicine. Not a position I had particularly aspired to, but I was interested in taking on that challenge, and it proved to be quite a challenge for me. I had to relearn internal medicine, and really all the subspecialties of medicine really became quite challenging to me. So my career has spanned sort of the entire spectrum, I suppose, as a clinical investigator, as an administrator, and now as a near end-of-my-career guy who writes ridiculous articles about grand rounds. Dr. Mikkael SekeresNot ridiculous at all. It was terrific. What was that like, having to retool? And this is a theme you cover a little bit in your essay, also, from something that's super specialized. I mean, you have had this storied career with the focus on lung cancer, and then having to expand not only to all of hematology oncology, but all of medicine. Dr. David JohnsonIt was a challenge, but it was also incredibly fun. My first few days in the chair's office, I met with a number of individuals, but perhaps the most important individuals I met with were the incoming chief residents who were, and are, brilliant men and women. And we made a pact. I promised to teach them as much as I could about oncology if they would teach me as much as they could about internal medicine. And so I spent that first year literally trying to relearn medicine. And I had great teachers. Several of those chiefs are now on the faculty here or elsewhere. And that continued on for the next several years. Every group of chief residents imparted their wisdom to me, and I gave them what little bit I could provide back to them in the oncology world. It was a lot of fun. And I have to say, I don't necessarily recommend everybody go into administration. It's not necessarily the most fun thing in the world to do. But the opportunity to deal one-on-one closely with really brilliant men and women like the chief residents was probably the highlight of my time as Chair of Medicine. Dr. Mikkael SekeresThat sounds incredible. I can imagine, just reflecting over the two decades that I've been in hematology oncology and thinking about the changes in how we diagnose and care for people over that time period, I can only imagine what the changes had been in internal medicine since I was last immersed in that, which would be my residency. Dr. David JohnsonWell, I trained in the 70s in internal medicine, and what transpired in the 70s was kind of ‘monkey see, monkey do'. We didn't really have a lot of understanding of pathophysiology except at the most basic level. Things have changed enormously, as you well know, certainly in the field of oncology and hematology, but in all the other fields as well. And so I came in with what I thought was a pretty good foundation of knowledge, and I realized it was completely worthless, what I had learned as an intern and resident. And when I say I had to relearn medicine, I mean, I had to relearn medicine. It was like being an intern. Actually, it was like being a medical student all over again. Dr. Mikkael SekeresOh, wow. Dr. David JohnsonSo it's quite challenging.  Dr. Mikkael SekeresWell, and it's just so interesting. You're so deliberate in your writing and thinking through something like grand rounds. It's not a surprise, David, that you were also deliberate in how you were going to approach relearning medicine. So I wonder if we could pivot to talking about grand rounds, because part of being a Chair of Medicine, of course, is having Department of Medicine grand rounds. And whether those are in a cancer center or a department of medicine, it's an honor to be invited to give a grand rounds talk. How do you think grand rounds have changed over the past few decades? Can you give an example of what grand rounds looked like in the 1990s compared to what they look like now? Dr. David JohnsonWell, I should all go back to the 70s and and talk about grand rounds in the 70s. And I referenced an article in my essay written by Dr. Ingelfinger, who many people remember Dr. Ingelfinger as the Ingelfinger Rule, which the New England Journal used to apply. You couldn't publish in the New England Journal if you had published or publicly presented your data prior to its presentation in the New England Journal. Anyway, Dr. Ingelfinger wrote an article which, as I say, I referenced in my essay, about the graying of grand rounds, when he talked about what grand rounds used to be like. It was a very almost sacred event where patients were presented, and then experts in the field would discuss the case and impart to the audience their wisdom and knowledge garnered over years of caring for patients with that particular problem, might- a disease like AML, or lung cancer, or adrenal insufficiency, and talk about it not just from a pathophysiologic standpoint, but from a clinician standpoint. How do these patients present? What do you do? How do you go about diagnosing and what can you do to take care of those kinds of patients? It was very patient-centric. And often times the patient, him or herself, was presented at the grand rounds. And then experts sitting in the front row would often query the speaker and put him or her under a lot of stress to answer very specific questions about the case or about the disease itself.  Over time, that evolved, and some would say devolved, but evolved into more specialized and nuanced presentations, generally without a patient present, or maybe even not even referred to, but very specifically about the molecular biology of disease, which is marvelous and wonderful to talk about, but not necessarily in a grand round setting where you've got cardiologists sitting next to endocrinologists, seated next to nephrologists, seated next to primary care physicians and, you know, an MS1 and an MS2 and et cetera. So it was very evident to me that what I had witnessed in my early years in medicine had really become more and more subspecialized. As a result, grand rounds, which used to be packed and standing room only, became echo chambers. It was like a C-SPAN presentation, you know, where local representative got up and gave a talk and the chambers were completely empty. And so we had to go to do things like force people to attend grand rounds like a Soviet Union-style rally or something, you know. You have to pay them to go. But it was really that observation that got me to thinking about it.  And by the way, I love oncology and I'm, I think there's so much exciting progress that's being made that I want the presentations to be exciting to everybody, not just to the oncologist or the hematologist, for example. And what I was witnessing was kind of a formula that, almost like a pancake formula, that everybody followed the same rules. You know, “This disease is the third most common cancer and it presents in this way and that way.” And it was very, very formulaic. It wasn't energizing and exciting as it had been when we were discussing individual patients. So, you know, it just is what it is. I mean, progress is progress and you can't stop it. And I'm not trying to make America great again, you know, by going back to the 70s, but I do think sometimes we overthink what medical grand rounds ought to be as compared to a presentation at ASH or ASCO where you're talking to subspecialists who understand the nuances and you don't have to explain the abbreviations, you know, that type of thing. Dr. Mikkael SekeresSo I wonder, you talk about the echo chamber of the grand rounds nowadays, right? It's not as well attended. It used to be a packed event, and it used to be almost a who's who of, of who's in the department. You'd see some very famous people who would attend every grand rounds and some up-and-comers, and it was a chance for the chief residents to shine as well. How do you think COVID and the use of Zoom has changed the personality and energy of grand rounds? Is it better because, frankly, more people attend—they just attend virtually. Last time I attended, I mean, I attend our Department of Medicine grand rounds weekly, and I'll often see 150, 200 people on the Zoom. Or is it worse because the interaction's limited? Dr. David JohnsonYeah, I don't want to be one of those old curmudgeons that says, you know, the way it used to be is always better. But there's no question that the convenience of Zoom or similar media, virtual events, is remarkable. I do like being able to sit in my office where I am right now and watch a conference across campus that I don't have to walk 30 minutes to get to. I like that, although I need the exercise. But at the same time, I think one of the most important aspects of coming together is lost with virtual meetings, and that's the casual conversation that takes place. I mentioned in my essay an example of the grand rounds that I attended given by someone in a different specialty who was both a physician and a PhD in biochemistry, and he was talking about prostaglandin metabolism. And talk about a yawner of a title; you almost have to prop your eyelids open with toothpicks. But it turned out to be one of the most fascinating, engaging conversations I've ever encountered. And moreover, it completely opened my eyes to an area of research that I had not been exposed to at all. And it became immediately obvious to me that it was relevant to the area of my interest, which was lung cancer. This individual happened to be just studying colon cancer. He's not an oncologist, but he was studying colon cancer. But it was really interesting what he was talking about. And he made it very relevant to every subspecialist and generalist in the audience because he talked about how prostaglandin has made a difference in various aspects of human physiology.  The other grand rounds which always sticks in my mind was presented by a long standing program director at my former institution of Vanderbilt. He's passed away many years ago, but he gave a fascinating grand rounds where he presented the case of a homeless person. I can't remember the title of his grand rounds exactly, but I think it was “Care of the Homeless” or something like that. So again, not something that necessarily had people rushing to the audience. What he did is he presented this case as a mysterious case, you know, “what is it?” And he slowly built up the presentation of this individual who repeatedly came to the emergency department for various and sundry complaints. And to make a long story short, he presented a case that turned out to be lead poisoning. Everybody was on the edge of their seat trying to figure out what it was. And he was challenging members of the audience and senior members of the audience, including the Cair, and saying, “What do you think?” And it turned out that the patient became intoxicated not by eating paint chips or drinking lead infused liquids. He was burning car batteries to stay alive and inhaling lead fumes, which itself was fascinating, you know, so it was a fabulous grand rounds. And I mean, everybody learned something about the disease that they might otherwise have ignored, you know, if it'd been a title “Lead Poisoning”, I'm not sure a lot of people would have shown up. Dr. Mikkael Sekeres That story, David, reminds me of Tracy Kidder, who's a master of the nonfiction narrative, will choose a subject and kind of just go into great depth about it, and that subject could be a person. And he wrote a book called Rough Sleepers about Jim O'Connell - and Jim O'Connell was one of my attendings when I did my residency at Mass General - and about his life and what he learned about the homeless. And it's this same kind of engaging, “Wow, I never thought about that.” And it takes you in a different direction.  And you know, in your essay, you make a really interesting comment. You reflect that subspecialists, once eager to share their insight with the wider medical community, increasingly withdraw to their own specialty specific conferences, further fragmenting the exchange of knowledge across disciplines. How do you think this affects their ability to gain new insights into their research when they hear from a broader audience and get questions that they usually don't face, as opposed to being sucked into the groupthink of other subspecialists who are similarly isolated? Dr. David Johnson That's one of the reasons I chose to illustrate that prostaglandin presentation, because again, that was not something that I specifically knew much about. And as I said, I went to the grand rounds more out of a sense of obligation than a sense of engagement. Moreover, our Chair at that institution forced us to go, so I was there, not by choice, but I'm so glad I was, because like you say, I got insight into an area that I had not really thought about and that cross pollination and fertilization is really a critical aspect. I think that you can gain at a broad conference like Medical Grand Rounds as opposed to a niche conference where you're talking about APL. You know, everybody's an APL expert, but they never thought about diabetes and how that might impact on their research. So it's not like there's an ‘aha' moment at every Grand Rounds, but I do think that those kinds of broad based audiences can sometimes bring a different perspective that even the speaker, him or herself had not thought of. Dr. Mikkael SekeresI think that's a great place to end and to thank David Johnson, who's a clinical oncologist at the University of Texas Southwestern Medical School and just penned the essay in JCO Art of Oncology Practice entitled "An Oncologist's Guide to Ensuring Your First Medical Grand Rounds Will Be Your Last."  Until next time, thank you for listening to JCO's Cancer Stories: The Art of Oncology. Don't forget to give us a rating or review, and be sure to subscribe so you never miss an episode. You can find all of ASCO's shows at asco.org/podcasts.  David, once again, I want to thank you for joining me today. Dr. David JohnsonThank you very much for having me. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.    Show notes: Like, share and subscribe so you never miss an episode and leave a rating or review.  Guest Bio: Dr David Johnson is a clinical oncologist at the University of Texas Southwestern Medical School.

random Wiki of the Day
USS Mercer (APL-39)

random Wiki of the Day

Play Episode Listen Later May 11, 2025 1:51


rWotD Episode 2929: USS Mercer (APL-39) Welcome to Random Wiki of the Day, your journey through Wikipedia's vast and varied content, one random article at a time.The random article for Sunday, 11 May 2025, is USS Mercer (APL-39).The second USS Mercer (APB 39/IX 502/APL 39) is an Benewah-class barracks ship of the United States Navy. Originally classified as Barracks Craft APL 39, the ship was reclassified as Self-Propelled Barracks Ship APB 39 on 7 August 1944. Laid down on 24 August 1944 by Boston Navy Yard, and launched on 17 November 1944 as APB 39, sponsored by Mrs. Lillian Gaudette, the ship was named Mercer, after counties in eight states, on 14 March 1945, and commissioned on 19 September 1945.This recording reflects the Wikipedia text as of 06:00 UTC on Sunday, 11 May 2025.For the full current version of the article, see USS Mercer (APL-39) on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Mastodon at @wikioftheday@masto.ai.Also check out Curmudgeon's Corner, a current events podcast.Until next time, I'm generative Ayanda.

Grand reportage
Comment Taïwan se prépare face à la Chine?

Grand reportage

Play Episode Listen Later Apr 9, 2025 19:30


L'armée populaire de libération (APL), munie de ses avions de chasse, d'une marine modernisée et d'une force de frappe infiniment supérieure, a intensifié sa pression sur Taïwan et ses 23 millions d'habitants. Face à Goliath, la petite île cherche à utiliser tous ses atouts pour rendre trop couteux le rêve de « réunification » de Xi Jinping.    De Nicolas Rocca envoyé spécial à Taïwan et Igor Gauquelin à Paris,Les mirages 2000 décollent et atterrissent dans un balai incessant sur la base aérienne de Hsinchu, chargés de protéger la capitale Taipei, à 80 km plus au nord. Cette ville de la côte ouest héberge aussi le siège de TSMC, l'entreprise dont les semi-conducteurs de pointe sont vitaux pour faire tourner l'économie planétaire. Quelques jours plus tôt, ont été lancés des exercices de « réponse immédiate » mobilisant toutes les branches de l'armée taïwanaise pour répliquer à la pression chinoise.« La plupart du temps, on prépare l'avion en quelques minutes, mais si on est très pressé, on peut aller plus vite », explique le lieutenant-colonel Wu Meng-che à côté d'un des 54 avions de chasses encore opérationnels parmi les 60 livrés par la France à la fin des années 1990.Pression croissanteSi ces chasseurs à la carlingue fatiguée sont encore opérationnels, c'est, notamment, car Taïwan fait face à un défi unique. Personne, sauf les États-Unis, n'accepte désormais de lui livrer des armes ou des équipements militaires de peur de fâcher le voisin chinois. Pourtant, l'année dernière, plus de 3 000 avions de l'APL [NDLR Armée populaire de libération, nom de l'armée chinoise] ont été identifiés dans l'ADIZ taïwanais (espace d'identification aérienne). Contre 972 en 2021. « La plupart du temps, on a déjà des avions dans les airs qui vont effectuer les vérifications nécessaires, mais parfois, on nous demande de décoller en urgence », assure le lieutenant-colonel de 39 ans. « Notre centre de commandement dit aux avions chinois : "Notre limite est ici, vous ne pouvez pas la franchir", mais eux répondent : "C'est notre territoire, notre espace aérien". » Une intimidation permise par le déséquilibre des forces. Malgré une récente livraison de 66 nouveaux F-16 américains, ses vieux mirages et sa production d'avions indigènes, Taïwan possède seulement un peu moins de 400 avions de chasses. La Chine, elle, en dispose de plus de 1 500. Un chiffre en constante augmentation.Ce déséquilibre est flagrant dans tous les secteurs. Amaigris par un taux de natalité en chute libre, les effectifs de l'armée taïwanaise ne cessent de se réduire. En plus du service militaire, allongé de quatre mois à un an, pour ceux nés après 2004, qui vient grossir le rang du 1,6 million de réservistes, l'armée compte sur ses soldats de métiers, plus 152 000 en 2024. Des chiffres limités face aux 2 millions de militaires de carrière de l'APL.Alors, dans les villes de l'île, des affiches sont placardées pour inciter les jeunes recrues à s'engager. « Moi, je veux bien faire carrière dans la marine, mon père me dit que c'est une bonne idée et que la paie est bonne », assure un jeune homme de 17 ans, emmené par son lycée au port de Keelung visiter deux frégates et un ravitailleur mis en avant par la marine. Même question à un adolescent, mais une réponse à l'opposée. « On n'apprend rien en un an de service militaire. Et si on va à la guerre, notre armée n'a pas la capacité de résister. Qu'est-ce que je dois faire ? Me battre ? Fuir ? » Des réactions qui témoignent de l'incertitude persistante sur la résilience taïwanaise en cas de conflit. « Cette question de l'esprit de défense à Taïwan n'est pas claire, résume Mathieu Duchatel, directeur du programme Asie à l'Institut Montaigne. Du côté de Pékin, on constate qu'il y a une erreur d'appréciation terrible de la Russie sur la détermination de l'Ukraine à résister. On peut même se dire que ce flou sur la réaction de la société taïwanaise est une forme de dissuasion pour la Chine. »À écouter aussiTaiwan secoué par les infiltrations chinoises« Porc-épic »Ce mot résume la mentalité de l'armée de l'île, symbolisée par ce pari d'une défense asymétrique ou celle dite du « porc-épic », selon les mots utilisés par l'ex-présidente Tsai Ying-wen. À l'image du rongeur, l'objectif est de rendre, avec des moyens limités, la proie taïwanaise trop dure à avaler pour le prédateur chinois. « L'armée est en transition, mais elle est héritière de celle du KMT (Guo Min-tank), qui a fui la Chine en 1949, avec des plateformes lourdes, des chars, des gros navires…, explique Tanguy Le Pesant, chercheur associé au Centre d'études français sur la Chine contemporaine. Maintenant, elle souhaite se doter d'armes plus petites et moins couteuses, des missiles anti-navires, des drones aériens, de surface, sous-marins. »Une mutation déjà bien entamée, avec une industrie locale dynamique permettant de produire missiles et drones en grande quantité. Mais la tradition persiste. « Il y a eu longtemps une inertie culturelle au sein de l'armée taïwanaise, favorable aux gros équipements qui sont aussi une cible facile », résume Marc Julienne, directeur du Centre Asie de l'Ifri. Une inertie loin d'avoir disparu, en témoigne le projet très décrié et onéreux du Hai Kun, premier sous-marin indigène, dont les derniers essais sont censés avoir lieu en avril 2025. Mais face à la flotte chinoise et sa soixantaine de sous-marins qu'elle devrait affronter dans un détroit peu profond, son utilité est très débattue. « L'autre élément pour Taïwan est d'utiliser la géographie de l'île à son avantage, explique Tanguy Lepesant : « Il existe une centaine de sommets permettant à l'armée taïwanaise de se cacher, d'envoyer des salves de missiles, et les côtes sont aussi à leur avantage, très difficiles d'accès et escarpées. » De quoi rendre un débarquement extrêmement complexe, malgré les imposantes barges développées récemment par l'APL.Si Taïwan ne manque pas d'atout pour décourager la Chine d'envahir, « notre sécurité dépend aussi de la crédibilité de l'armée américaine dans la région », reconnaît François Wu, vice-ministre des Affaires étrangères de l'île. Et rien de tel pour garantir le soutien continu de Washington que de préserver la place centrale de Taïwan au sein de l'économie mondiale. 68% des semi-conducteurs sont produits par des entreprises taïwanaises et 90% des puces les plus innovantes par TSMC, qui vient d'investir 100 milliards de dollars aux États-Unis. Cette industrie, surnommée « bouclier du silicium », semble représenter une assurance-vie encore plus cruciale que son armée, pour l'île de 23 millions d'habitants.

Innovation Now
Parker Takes the Trophy

Innovation Now

Play Episode Listen Later Apr 7, 2025


For the fourth year in a row, NASA is the proud recipient of the prestigious Collier Trophy.

Mock and Daisy's Common Sense Cast
Dem Mayors GRILLED By Congress, DJ Daniel Steals Our Hearts, And Cory Booker Is Really Creepy

Mock and Daisy's Common Sense Cast

Play Episode Listen Later Mar 6, 2025 86:38


We hit the ground running with a CBS poll dissecting Trump's latest speech, and DJ Daniel stirring the pot in the media. As Democrats falter in facing non-victim narratives, Trump's fiery social media takes and Don Jr.'s insights on the State of the Union stoke the flames.Tensions rise with Cory Booker's bizarre influencer interview antics and Byron Donalds' relentless grilling of sanctuary city spending. Discussions heat up over immigration policies, culminating in Rep. Mace's scorching critique of Chicago.The episode peaks with Trump's bold declaration on gender, Charlie Kirk's controversial study, and Megyn Kelly's fierce takedown of John Fetterman. Wrapping up, Trump sends a stark message to Hamas, and the clash between Andrew Tate and DeSantis ignites debate. Tune in for an unmissable, fiery discourse on today's most pressing political issues.Visit https://readywise.com/ code CHICKS10 for 10% off your entire purchase. Prepare when times are good, so you are ready when they are bad.Lose weight the smarter way.  Visit https://TakeLean.com and use code Chicks20 for 20% off your first order.Never run out of MEAT go to https://omahasteaks.com/CHICKS subscribe and get 12 FREE burgers, FREE shipping, and an EXTRA 10% OFF. Minimum purchase may apply.Maximize your rest as Daylight Savings Time begins! Visit https://HealthyCell.com/Chicks code CHICKS to get REM Sleep and 20% off your first order

Text Me Back! With Lindy West And Meagan Hatcher-Mays
Lindy and Meagan Sleep Their Way to the Top (with Big Fig AND Big Ron)

Text Me Back! With Lindy West And Meagan Hatcher-Mays

Play Episode Listen Later Feb 27, 2025 45:54


Today, Lindy and Meagan are recording this episode in their most natural state: lying down.That's right–these two sleepy gals are broadcasting from a very fancy Big Fig mattress at On Air Fest in Brooklyn, NYC aka DA BIG APPLE. And they're not alone! They're in bed with the biggest grifter in the biz, a legendary podcast king and professional menace…Ronald Young Jr. Big Ron gives us the scoop on New York's hottest restaurants (a sexy little local joint~Aplé-beis~), gives us many a glad tiding, and tells us Watch-him Watchin! Are you watching Lady Matlock??? Tell us your thoughts!!! BFF Party Line: (703) 829-0003.If you'd like to keep Meagan licensed to practice law in New York, DONATE $400 TO OUR PATREON patreon.com/textmebackpodDo we really have to watch Beast Games, Suits, or Succession?

For Vuck's Sake
S10 Ep19 - Vs Wellington Phoenix

For Vuck's Sake

Play Episode Listen Later Feb 18, 2025 40:31


It was looking like a pretty familiar story but a second half change made all the difference as the Vuck took the points against Wellington Phoenix while the Wuck professionally took care of Central Coast. Follow us on Twitter, Instagram & FacebookSupport us on PatreonListen to our interview with John Stensholt regarding Melbourne Victory's finances HEREMON THE VUCK

OPOSICIONES DE EDUCACIÓN
Cómo ser productivo y aprovechar tu tiempo según la ciencia

OPOSICIONES DE EDUCACIÓN

Play Episode Listen Later Feb 18, 2025 9:03


Si quieres aumentar tu confianza, reducir la ansiedad y multiplicar tus probabilidades de éxito, necesitas un plan estructurado de estudio. En este video, te comparto 7 leyes de productividad diseñadas específicamente para opositores, basadas en la evidencia y en estrategias probadas por miles de personas que ya han conseguido su plaza. Menos esfuerzo, más resultados. ¡Aplícalas desde hoy! ➡️ Apúntate gratis al Consejo Educativo diario y recíbelo todos los días a las 15h para ser mejor docente: https://preparadoredufis.com/consejo-educativo-diario/ ════════════════ Secciones de nuestro canal por categorías ➜ Encuéntralas aquí: https://www.youtube.com/c/OposicionesdeEducaci%C3%B3n/playlists ════════════════ ⚡️ ¿YouTube se te queda corto y quieres ir más allá? ¡Síguenos en otras redes sociales! Instagram: https://www.instagram.com/diegofuentes.oposiciones TikTok: https://www.tiktok.com/@diegofuentes.oposiciones Mi web: https://preparadoredufis.com/ ════════════════ ÍNDICE DE VÍDEO 0:00 Introducción al vídeo 0:52 Trabajo inteligente, no duro 2:05 Aprovecha la presión a tu favor (Ley de Yerkes-Dodson) 3:12 Estado de flow y sesiones de estudio progresivas 4:30 Deja tareas inacabadas para potenciar la memoria (Efecto Zeigarnik) 5:35 Usa fechas límite para evitar procrastinar (Ley de Parkinson) 6:20 Enfócate en lo que realmente importa (Ley de Pareto) 7:10 Ataca lo más difícil primero (Ley de Laborit) 8:00 Cómo aplicar estas leyes en tu rutina de estudio ¡Suscríbete al canal y dale like para más estrategias que te acerquen a tu plaza soñada!

the ecoustics podcast
Can Dolby Atmos Sound Better Over Headphones? Hyunkook Lee of APL says, "YES!"

the ecoustics podcast

Play Episode Listen Later Feb 5, 2025 45:51


While Apple Music, TIDAL and Amazon Music are all pushing spatial audio and immersive sound as the next big thing, the current reality is that, to get the best, most immersive effect, you need speakers: lots and lots of speakers. Of course, you *can* listen to immersive sound formats like Dolby Atmos and DTS:X on headphones, but the current processes to render a multi-channel recording into a 2-channel binaural signal, suitable for playback on headphones, leave room for improvement.APL (Advanced Psychoacoustics Lab) is dedicated to fixing this problem. The company's Virtuoso software can convert any 2-channel or multi-channel recording to a standard binaural headphone mix that maintains all the sonic cues of a real three-dimensional mix or space. Join eCoustics CEO Brian Mitchell on this episode of the eCoustics podcast as he chats with APL founder Professor Hyunkook Lee to discuss the current state of immersive sound over headphones and what can be done to make it better.Learn more at:https://apl-hud.com/Keep up with the latest audio and video news at https://www.ecoustics.comThank you to our sponsors SVS & Q Acoustics! For more information on these stellar brands, please click the links below: https://www.svsound.comhttps://www.qacoustics.comCredits:• Original intro music by The Arc of All. sourceoflightandpower.bandcamp.com• Voice Over Provided by Todd Harrell of SSP Unlimited. https://sspunlimited.com• Production by Mitch Anderson, Black Circle Studios. https://blackcircleradio.com#dolbyatmosheadphones #binauralsound #immersivesound #dolbyatmos #spatialaudio #virtuososoftware #aplaudio #aesnews #aes #audioengineers

Who? Weekly
Apl.de.ap, Daniel Powter & Brandon Routh?

Who? Weekly

Play Episode Listen Later Jan 24, 2025 84:13


Happy Friday, Wholigans! On today's episode of Who's There, our weekly call-in show, we celebrate Conclave's Oscar nominations (#ThisIsNotAConclavePodcast) before taking your comments about Christine Quinn's hatred for oligarchs and the horrible Who that the two Entrepreneurial Jessicas have in common. Moving on, it's time for questions about Bowen Yang and Rachel Sennott's latest gig, what Apl.de.ap and Taboo are up to (along with the iconic name for Black Eyed Peas stans), Daniel Powter's international success, whether or not the Superman Curse will affect David Corenswet, and more! As always, call in at 619.WHO.THEM to leave questions, comments & concerns for a future episode of Who's There?. Get a ton of bonus content over on Patreon.com/WhoWeekly To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

Procento Miloše Čermáka
Nejtěžší úkol pro Českou televizi je přijít na to, jak může veřejnoprávní služba dávat smysl lidem, kteří vyrostli na úplně jiých technologiích než my, říká místopředseda Rady ČT Ivan Tesař (263)

Procento Miloše Čermáka

Play Episode Listen Later Jan 19, 2025 93:51


Říká, že rok 2024 pro něj byl dobrý rok. Vydal knížku, syn se dostal na gymnázium a hodně cestoval. Ivan Tesař se stal ve dvaapadesáti překvapivým debutantem, když v brněnském nakladatelství Větrné mlýny vydal sbírku povídak a poetických textů s názvem Na kusy. Bývalý novinář a mediální analytik, který byl letech 2011 až 2017 členem Rady Českého rozhlasu, je od konce roku 2023 místopředsedou Rady České televizi. V zajímavém a dramatickém období, kdy veřejnoprávní televize nemá vyřešeno financování (čeká se na zvýšení koncesionářských poplatků parlamentem), a zároveň se vede debata o jejím smyslu. O tom jsme spolu v podcastu mluvili, a taky o psaní, stárnutí a světě.Zde je jako obvykle článek, který na základě přepisu napsala AI, Claude 3,5. Sonnet -Ivan Tesař: Po padesátce vydal svou první knihu, chystá přechod Apl se synem a možná napíše román o české dušiV době, kdy většina lidí hodnotí uplynulý rok jako mimořádně složitý, sedí ve studiu muž, který s úsměvem tvrdí opak. Ivan Tesař, spisovatel, analytik a místopředseda Rady České televize, představuje mix zdánlivých protikladů: člověk, který dokáže předpovědět geopolitické krize, ale zároveň píše poezii; profesionál analyzující tvrdá data, který však věří v sílu osobních příběhů.Jeho profesní dráha připomíná film o transformaci 90. let: od kulisáka v legendárním Branickém divadle, přes meteorický vzestup v médiích až po vedení ekonomického zpravodajství v agentuře v pouhých dvaadvaceti letech. "Bylo to vtipné, když si pro rozumy přijel dvacetiletý kluk do Vídně, a tam byl na jeho pozici šéfredaktor, kterému bylo šedesát," vzpomíná s úsměvem.Dnes se Tesař živí analýzou globálních událostí pro soukromé subjekty. Jeho tým dokázal předpovědět ruskou invazi na Ukrajinu půl roku před jejím začátkem. "Pokud jsi schopen se prohrabávat stovkami informací každý den a máš dostatečnou erudici na jejich interpretaci, dosáhneš úspěšnosti předpovědí kolem 85 procent," vysvětluje.Paralelně s analytickou prací se však věnuje literatuře. Jeho nedávno vydaná kniha, kombinující povídky a poezii s fotografiemi uznávaného Karla Cudlína, představuje odvážný experiment. "Vydavatelé tento mix žánrů obvykle nesnášejí," přiznává, "ale Větrné mlýny to riskovaly."Jako člen Rady České televize se Tesař potýká s existenciálními otázkami veřejnoprávních médií. Poukazuje na kritický stav financování ČT, kde rezervy dramaticky klesly z 3,8 miliardy na pouhých 350 milionů korun. Zároveň přichází s radikálním návrhem: omezit funkční období ředitelů na maximum dvou období. "Po určité době začneš jet podle zaběhnutého mustru a nevytvoříš tlak na inovace," argumentuje.Jeho nový literární projekt slibuje být ambiciózní: generační román o devadesátiletém muži, jehož život kopíruje historii Československa a České republiky. "Je to neskutečný příběh člověka, který přežil od 30. let přes protektorát, rok 1948, šedesátá léta, normalizaci až do současnosti," popisuje.Mezi jeho literární vzory patří Jan Zábrana, Jan Balabán a Georg Sebald - autoři, kteří mistrovsky zachycují osobní příběhy na pozadí velkých dějinných událostí. Tato inspirace se odráží i v jeho vlastní tvorbě, kde se snaží propojit osobní a historickou rovinu vyprávění.Přestože se pohybuje ve světě vysoké politiky a médií, neztrácí kontakt s osobní rovinou života. Na léto 2025 plánuje se svým patnáctiletým synem náročný přechod Alp: 670 kilometrů a 31 000 výškových metrů za 32 dní. "Vnímám to jako poslední velkou společnou akci se synem, než se vydá vlastní cestou," říká.Tesařův příběh ukazuje, že i v době specializace je možné propojovat zdánlivě neslučitelné světy - analytickou přesnost s uměleckou citlivostí, profesionální odstup s osobní angažovaností. Jeho optimistický pohled na svět přitom není naivní - je to optimismus člověka, který vidí do temných zákoutí světové politiky, ale přesto věří v lepší budoucnost.

Blood Podcast
Iron overload aggravates MDS pathophysiology; long-term outcomes after TPO-RA treatment in ITP; new insights into APL treatment outcomes by age and risk

Blood Podcast

Play Episode Listen Later Jan 9, 2025 17:20


In this week's episode we'll learn about the role of iron in myelodysplastic syndromes, or MDS. After that: long-term treatment outcomes in immune thrombocytopenia from the STOPAGO study.  Finally, new insights into APL treatment outcomes and prognostic factors from the large-scale Harmony APL project which used ATRA-Arsenic combination therapy.Featured Articles:Genetic iron overload aggravates, and pharmacological iron restriction improves, MDS pathophysiology in a preclinical studyLong-term follow-up of the STOPAGO studyAcute promyelocytic leukemia: long-term outcomes from the HARMONY project

The Startup CPG Podcast
#175 - E-Comm Wizards: David Fudge of Aplós

The Startup CPG Podcast

Play Episode Listen Later Dec 24, 2024 58:08


In this episode of the Startup CPG podcast, Daniel Scharff sits down with David Fudge, co-founder of Aplós, to discuss the journey of building a premium non-alcoholic spirits brand. David shares insights from his time leading brand at Bonobos, where he helped pioneer the direct-to-consumer model, and how those experiences informed his approach to creating Aplós—a brand redefining the cocktail experience without compromise.They explore the growing non-alcoholic beverage market, the importance of thoughtful branding, and how Aplós balances innovation and tradition with the help of renowned mixologist Lynette Marrero. David provides actionable strategies for scaling an e-commerce business, including influencer partnerships, creative optimization, and leveraging AI tools to stay ahead in a competitive landscape.David also reflects on lessons learned from both successes and missteps, offering actionable advice for aspiring founders looking to carve out a space in competitive markets. Whether you're interested in building a brand, excelling in e-commerce, or creating a product that stands the test of time, this episode is packed with valuable takeaways.Don't miss this engaging conversation with one of the most thoughtful minds in CPG —tune in now!Listen in as they share about:The Vision and Product Development of AplósThe Evolution of the Non-Alcoholic Beverage MarketBranding and Marketing StrategyE-commerce StrategiesNotable Challenges and Low ROI learningsTools and RecommendationsAdvice for EntrepreneursEpisode Links:Website: https://www.aplos.world/ LinkedIn: https://www.linkedin.com/in/dwfudge/ Don't forget to leave a five-star review on Apple Podcasts or Spotify if you enjoyed this episode. For potential sponsorship opportunities or to join the Startup CPG community, visit http://www.startupcpg.com.Show Links:Transcripts of each episode are available on the Transistor platform that hosts our podcast here (click on the episode and toggle to “Transcript” at the top)Join the Startup CPG Slack community (20K+ members and growing!)Follow @startupcpgVisit host Daniel's Linkedin Questions or comments about the episode? Email Daniel at podcast@startupcpg.comEpisode music by Super Fantastics

The Cody Askins Podcast Network
Every Insurance Agency Owner Needs This Service! (Cody Askins & Alison Sosa)

The Cody Askins Podcast Network

Play Episode Listen Later Nov 15, 2024 18:48


In this episode, Cody Askins sits down with Alison Sosa to dive into a game-changing service that every insurance agency owner needs: APL, the best solution for commission accounting!

Transform
Shoot the Shit: All the Juicy Details from Sami's Joint Bach

Transform

Play Episode Listen Later Oct 16, 2024 52:24


In this episode of Transform, the Samis are spilling all the tea about Sami B's joint bachelor/bachelorette weekend! From why they chose a joint celebration to why Austin was the perfect destination, they're diving into all the behind-the-scenes details.Tune in as they chat about everything from the pre-trip prep to the wild itinerary (and yes, the moment Sami Clarke's phone took a dive into Lake Austin). This episode is packed with giggles, stories, and all the bach weekend tea!Transform Instagram - click here!Sami Spalter Instagram - click here!Sami Clarke Instagram - click here!FORM Shop - click here!FORM Website - click here!The house that we rented in Austin on the lake for sami's bach - click here!Frankies bikinis- click here!Kopari gold sunscreen- click here!Lands end big tote bags- click here!Kat the label lingerie- click here!Form lounge sets- click here!Form espresso sets- click here!Form thunderstorm set- click here!APL slides- click here!Funboy lake float- click here!Code TRANSFORM for 20% off an annual membership.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Go to Hungryroot.com/TRANSFORM to get 40% off your first delivery and get your free veggies.Seed.com/transform and use code 25TRANSFORM to get 25% off your first month.Get 25% off your first month at ritual.com/TRANSFORM.Taylor Farms Chopped Salad Kits are available at all major grocery stores.Visit weliveconscious.com and use code TRANSFORM at checkout for 15% off your first purchase.Make switching seasons a breeze with Quince's high-quality closet essentials. Go to Quince.com/transform for free shipping on your order and 365-day returns.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Fringe Radio Network
Adventures of Captain Epoch Ep 60: Wibbly Wobbly Timey Whimey

Fringe Radio Network

Play Episode Listen Later Oct 15, 2024 72:17


Tonight we look at a possible time traveler and some of the things he said before heading back.-=Links=-If you would like to join in on the conversation, Join me on Discord.Discord: https://discord.gg/a6UJEb5Dj3Twitter: https://twitter.com/magicsenshiRumble: https://rumble.com/c/c-5613161Fringe Radio: https://fringeradionetwork.com/liveSpirit Force: https://faithbucks.comIf you would like to be a guest on the show or have a topic that you want explored, please Email me with the subject "Guest"Email: captainepoch79@proton.meIf you want to support this Podcast,https://paypal.me/Magicslayer/Cashapp $CaptainEpochMusic by UDIO 

The Fellow on Call
Episode 114: Acute Promyelocytic Leukemia (REBOOT!)

The Fellow on Call

Play Episode Listen Later Sep 4, 2024


By popular demand, our next series that we are excited to share with you is on MDS/AML! As we prepare for the release of the first episode next week, let's throw it back to Episode 019 in our Heme/Onc Emergencies Series and talk about APL!Episode contents: - How do we diagnose APL? - What are characteristic findings of APL? - What is the acute management of this disease? ****Have some time and want to make some extra money? Get paid to participate in market research surveys: https://affiliatepanel.members-only.online/FOC_24?utm_campaign=FOC&utm_source=email&utm_medium=email** Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodesLove what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast