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Radiation therapy or radiotherapy, is a common treatment for cancer, but its effectiveness differs across patients. A recent study published as the cover for Volume 17, Issue 2 of Aging explored why this happens. The findings provide valuable insights, particularly for brain cancers like glioblastoma (GBM) and low-grade gliomas (LGG). Understanding Glioblastoma and Low-Grade Gliomas Glioblastoma and LGG are both brain tumors, but they behave in very different ways. GBM is highly aggressive, with most patients surviving only 12 to 18 months, even with surgery, chemotherapy, and radiation therapy. LGG, on the other hand, grows more slowly, and many patients live for decades with proper care. Despite their differences, LGG and GBM are biologically linked. Some LGG tumors eventually transform into GBM, making early treatment decisions critical. Given radiation therapy's effectiveness in GBM, it has often been assumed that LGG patients would also benefit from it. However, a new study titled “Variability in radiotherapy outcomes across cancer types: a comparative study of glioblastoma multiforme and low-grade gliomas” challenges this assumption. Full blog - https://aging-us.org/2025/03/how-radiation-therapy-affects-tumors-glioblastoma-vs-low-grade-gliomas/ Paper DOI - https://doi.org/10.18632/aging.206212 Corresponding author - Morten Scheibye-Knudsen - mscheibye@sund.ku.dk Video short - https://www.youtube.com/watch?v=j91rzDJHXTE Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206212 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, cancer, biomarkers, radiotherapy, GBM, LGG, survival About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
BUFFALO, NY — March 3, 2025 — A new #research paper was #published in Aging (Aging-US) on February 27, 2025, as the #cover of Volume 17, Issue 2, titled “Variability in radiotherapy outcomes across cancer types: a comparative study of glioblastoma multiforme and low-grade gliomas.” An international research team, led by first author Alexander Veviorskiy from Insilico Medicine AI Limited, Abu Dhabi, UAE, and corresponding author Morten Scheibye-Knudsen from the Center for Healthy Aging, University of Copenhagen, investigated how radiotherapy affects survival in different types of cancer, with a special focus on glioblastoma multiforme (GBM) and low-grade gliomas (LGG). Their findings reveal that radiotherapy has opposite effects in GBM and LGG patients. The study highlights key biological differences between these brain cancer types, emphasizing the need for personalized treatment strategies. Radiotherapy is a standard treatment for many tumors, but its effectiveness varies widely depending on the type of cancer. The researchers began by analyzing data from 32 cancer types using information from The Cancer Genome Atlas (TCGA). They then focused on glioblastoma multiforme (GBM) and low-grade gliomas (LGG), two types of brain cancer with distinct biological behaviors. GBM is an aggressive cancer with poor survival rates, whereas LGG progresses more slowly and often has a better prognosis. “GBM and LGG are particularly interesting to study together because GBM often originates from a preexisting LGG, representing a progression from a lower-grade to a higher-grade malignancy.” The results revealed a striking contrast: patients with GBM who received radiotherapy lived longer, whereas those with LGG had shorter survival times after treatment. To understand the reasons behind this, the researchers analyzed gene expression and signaling pathways. They identify several biological processes that may influence radiotherapy outcomes. For example, GBM tumors have weaker DNA repair mechanisms, making them more vulnerable to radiation-induced damage, which allows radiotherapy to effectively kill cancer cells. In contrast, LGG tumors have stronger DNA repair systems, helping cells survive radiation better and potentially reducing the treatment's effectiveness. Additionally, differences in immune system activity and genetic mutations—such as EGFR alterations—were linked to worse survival in LGG patients who received radiotherapy. These findings highlight the need for a more personalized approach to treating brain cancer. The study proposes that a universal approach to radiotherapy is not appropriate, particularly for patients with LGG. Instead, personalized treatment strategies based on genetic and molecular characteristics could improve patient survival outcomes. The research also raises the possibility of combining radiotherapy with targeted therapies, such as immune-boosting therapies or DNA repair inhibitors, to enhance its effectiveness. In conclusion, this study highlights the complexity of brain cancer treatment and the need for further research to refine therapeutic strategies. By understanding the molecular and genetic differences between the different types of cancers, more effective and personalized approaches can be developed to improve survival and quality of life for brain cancer patients. DOI - https://doi.org/10.18632/aging.206212 Corresponding author - Morten Scheibye-Knudsen - mscheibye@sund.ku.dk Video short - https://www.youtube.com/watch?v=j91rzDJHXTE Visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
welcome back LGG! today's episode is ALL about handling the cold weather and the depression that comes with it, AKA winter blues. The days are ending earlier and the nights are lasting longer, and it can be so hard to stick to your goals and stay motivated throughout this season, but today, Amri is tackling the winter blues and helping you get through it too with her top tips for handling seasonal depression well. just remember, you're never alone
Wetzlarer Tafel unter Druck, Löhnberg eröffnet Insolvenzverfahren zu Löhnberger Grundbesitz GmbH LGG und Scharlach-Fälle bei Kindern gestiegen. Alle Hintergründe zu den Nachrichten finden Sie hier: https://www.mittelhessen.de/lokales/lahn-dill-kreis/wetzlar/zum-advent-weniger-lebensmittelspenden-fuer-die-tafel-4196772 https://www.mittelhessen.de/lokales/kreis-limburg-weilburg/landkreis-limburg-weilburg/insolvenzantrag-in-loehnberg-stock-zieht-bei-lgg-reissleine-4212932 https://www.mittelhessen.de/lokales/lahn-dill-kreis/wetzlar/last-christmas-fuer-marie-bernals-modehaus-am-wetzlarer-dom-4201824 https://www.mittelhessen.de/politik/politik-hessen/hessische-gruenen-vorsitzende-kathrin-anders-tritt-zurueck-4213016 https://www.mittelhessen.de/ratgeber/gesundheit/krankenkasse-deutlich-mehr-kinder-mit-scharlach-4206623 Ein Angebot der VRM.
In this episode, I'm diving deep into one of my absolute favourite topics - gut health! As someone who's been fascinated by the gastrointestinal system since my Year 9 biology days, I'm thrilled to share the latest research about pre, pro, and particularly postbiotics. This episode builds upon our previous discussion in Episode 30 - Probiotics and Prebiotics in Children, taking your understanding of gut health to the next level! Key Points We'll Cover: 1. Gut-Brain Connection Your gut truly is your second brain - discover how this amazing connection impacts your child's mood, cognition and overall health 2. Microbiome Magic Learn why a balanced gut microbiome is crucial for nutrient absorption and immune system function 3. Fibre Facts Explore practical ways to boost your child's fibre intake through everyday foods - it's simpler than you think! 4. Probiotic Power Understanding which probiotic strains actually survive stomach acid and why the LGG strain is particularly beneficial for children 5. Postbiotic Potential Discover these fascinating compounds produced by your gut bacteria and how they benefit your child's health Helpful Resources:
Derrière le nom Lemon Schaden se cache l'alias production et live de Eendracht. Résident et membre du collectif ÖND à Rennes, cet infatigable producteur s'amuse sans retenue à mélanger la douceur des samples Ambient à la violence des kicks hardcore.TRACKLIST :Première partie - Live Lemon Schaden - Intro Live UnreleasedLemon Schaden - Kid Live UnreleasedCapon - Soundscape (Lemon Schaden Live Edit) UnreleasedLemon Schaden - Lfo Birds Live UnreleasedLemon Schaden - Triple B Live UnreleasedLemon Schaden - Spray Live UnreleasedLemon Schaden - The City Live UnreleasedLemon Schaden - Can't Remember Live UnreleasedLemon Schaden - The Sound System Got U Pretty Live Unreleased Lemon Schaden - Zozo Live Unreleased + Republicans Are Morons Lemon Schaden - Lutin Matin Live Unreleased + Republicans Are MoronsDeuxième Partie :Lemon Schaden - Bass Planet Map UnreleasedLemon Schaden - 6 AM Ballad UnreleasedLemon Schaden - Bloom 2684 Unreleased (DLZ x Electronic Consortium)deux_pack - Two Gates Unreleased (Bella Ursa Recordings)Lord Jalapeños (Lemon Schaden Remix) Unreleased (Ethos Records)reallyraw. - UnrealeasedCorsen - Unreleased (Armen x LGG x Garage 83C)AJO - Unreleased (La Serpiente Remix) [Ethos Records]Lemon Schaden - Sample PackLemon Schaden - Mémoires de Bertheaume UnreleasedLemon Schaden - Syncope Unreleased (Armen x LGG x Garage 83C)Lemon Schaden - La Vie est Un After Paisible (Tribute to Kerouzic) Unreleased (Underwater Audio Dynamics) Lemon Schaden - Dancer's Pit Unreleased Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Derrière le nom Lemon Schaden se cache l'alias production et live de Eendracht. Résident et membre du collectif ÖND à Rennes, cet infatigable producteur s'amuse sans retenue à mélanger la douceur des samples Ambient à la violence des kicks hardcore. TRACKLIST : Première partie - Live Lemon Schaden - Intro Live Unreleased Lemon Schaden - Kid Live Unreleased Capon - Soundscape (Lemon Schaden Live Edit) Unreleased Lemon Schaden - Lfo Birds Live Unreleased Lemon Schaden - Triple B Live Unreleased Lemon Schaden - Spray Live Unreleased Lemon Schaden - The City Live Unreleased Lemon Schaden - Can't Remember Live Unreleased Lemon Schaden - The Sound System Got U Pretty Live Unreleased Lemon Schaden - Zozo Live Unreleased + Republicans Are Morons Lemon Schaden - Lutin Matin Live Unreleased + Republicans Are Morons Deuxième Partie : Lemon Schaden - Bass Planet Map Unreleased Lemon Schaden - 6 AM Ballad Unreleased Lemon Schaden - Bloom 2684 Unreleased (DLZ x Electronic Consortium) deux_pack - Two Gates Unreleased (Bella Ursa Recordings) Lord Jalapeños (Lemon Schaden Remix) Unreleased (Ethos Records) reallyraw. - Unrealeased Corsen - Unreleased (Armen x LGG x Garage 83C) AJO - Unreleased (La Serpiente Remix) [Ethos Records] Lemon Schaden - Sample Pack Lemon Schaden - Mémoires de Bertheaume Unreleased Lemon Schaden - Syncope Unreleased (Armen x LGG x Garage 83C) Lemon Schaden - La Vie est Un After Paisible (Tribute to Kerouzic) Unreleased (Underwater Audio Dynamics) Lemon Schaden - Dancer's Pit Unreleased
heyy LGG fam! This week, amri talks all things aesthetics and finding the perfect aesthetic to suit you. She also touches on the importance of identity and staying true to yourself while trying out different aesthetics, and always doing what YOU want to do, not what the trends say are popular! Tune in for a vulnerable chat while amri takes you through her journey of finding herself and her aesthetic! If you enjoyed this episode, please leave a rate and review
Workup and management of LGG in Radiation Oncology featuring guest Dr Nancy Zhou
hey LGG gang! this week's episode is a no script no notes, real talk chat on all things life and faith and relationships. As amri chats, she ends up landing on the topic of staying consistent to goals, so tune in if you want to hear some motivation on how to stay consistent and achieve your dreams, as well as 5 goals that amri has for her month
BUFFALO, NY- January 30, 2024 – A new #research paper was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, “XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis.” X-ray repair cross-complementation group 1 (XRCC1) is a pivotal contributor to base excision repair, and its dysregulation has been implicated in the oncogenicity of various human malignancies. However, a comprehensive pan-cancer analysis investigating the prognostic value, immunological functions, and epigenetic associations of XRCC1 remains lacking. In this new study, researchers Guobing Wang, Yunyue Li, Rui Pan, Xisheng Yin, Congchao Jia, Yuchen She, Luling Huang, Guanhu Yang, Hao Chi, and Gang Tian from Southwest Medical University, The Affiliated Hospital of Southwest Medical University, Yibin Hospital of T.C.M, Medical School of Nanchang University, Fourth Military Medical University, and Ohio University aimed to address this knowledge gap by conducting a systematic investigation employing bioinformatics techniques across 33 cancer types. “Our analysis encompassed XRCC1 expression levels, prognostic and diagnostic implications, epigenetic profiles, immune and molecular subtypes, Tumor Mutation Burden (TMB), Microsatellite Instability (MSI), immune checkpoints, and immune infiltration, leveraging data from TCGA, GTEx, CELL, Human Protein Atlas, Ualcan, and cBioPortal databases.” Notably, XRCC1 displayed both positive and negative correlations with prognosis across different tumors. Epigenetic analysis revealed associations between XRCC1 expression and DNA methylation patterns in 10 cancer types, as well as enhanced phosphorylation. Furthermore, XRCC1 expression demonstrated associations with TMB and MSI in the majority of tumors. Interestingly, XRCC1 gene expression exhibited a negative correlation with immune cell infiltration levels, except for a positive correlation with M1 and M2 macrophages and monocytes in most cancers. Additionally, the researchers observed significant correlations between XRCC1 and immune checkpoint gene expression levels. Lastly, their findings implicated XRCC1 in DNA replication and repair processes, shedding light on the precise mechanisms underlying its oncogenic effects. “Overall, our study highlights the potential of XRCC1 as a prognostic and immunological pan-cancer biomarker, thereby offering a novel target for tumor immunotherapy." DOI - https://doi.org/10.18632/aging.205426 Corresponding authors - Guanhu Yang - guanhuyang@gmail.com, Hao Chi - Chihao7511@163.com, and Gang Tian - tiangang@swmu.edu.cn Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, X-ray repair cross-complementation group 1, pan-cancer, prognosis, immune infiltration, tumor microenvironment About Aging-US Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
In this week's episode Matteus looks at English Feudalism and how we can use it to develop those realms labelled as "Feudal" in LGG.
This episode of Ray Ray's Podcast is sponsored by Spotify for Podcasters and Lyrically Correct, in partnership with Pandora. On this episode, We talked with Victoria Castillo (@victoriacastillo____) owner of VC marketing agency and Cowshmere Boutique. We talked with Victoria about what she has done since her last appearance on “Ray Ray's Podcast”, “Cowshmere” Boutique, her “LGG” group, and much more. We would like to give a big shoutout to Tite for providing our intro music from his single "Get'n Paid" featuring Chalie Boy. Our podcast is recorded on the 9th floor of Hello Studios. Visit our Website www.RayRaysPodcast.com for all of our fantastic content. Continue to follow us on all social media IG @rayrays_podcast Facebook.com/RayRaysPodcast and TikTok @rayrayspodcast. Follow us on youtube. Like and Subscribe on Youtube Please. --- Send in a voice message: https://podcasters.spotify.com/pod/show/rayrays/message
في هذه الحلقة تكلّمنا عن انطباعاتنا لفيلمGran TurismoولعبةBaldur's Gate III و Airhead (Demo)بالإضافة الى أخبار ناقشناها مثل الألعاب الجديدة المضافة لبلايستيشن بلس وجيم باس وغيره!ألعاب تكلمّنا عنها وبالترتيب:Baldur's Gate IIIAirhead (Demo)الحضور:فهد يوسفرواح المعيقلعمر اليوسفعادل باجنيد00:00 المقدمة 07:10 Gran Turismo 17:25 Gamers820:40 Baldur's Gate III50:17 Airhead (Demo)53:59 شباب LGG راح يعلقون على بطولة كابكوم ورلد تور54:52 تصحيح أحمد53:28 جيف كيلي سيتحدث عن الألعاب القادمة خلال 12 شهر في جيمزكوم57:22 إعلانات THQ01:00:09 ستارفيلد استوت 01:00:43 متابعة إعلانات THQ 01:04:07 تقديم موعد Assassin's Creed Mirage 01:05:10 موعد فاينل فانتاسي ايفر كراسيس 01:05:43 ألعاب الجيم باس 01:08:41 ألعاب بلايستيشن بلس01:10:07 اختيار ممثل زافالا الجديد01:11:34 فريق عمل فيلم انتشارتد يرغب بالعمل على جزء ثاني 01:12:18 هاشتاق ألعاب==================================================تابعوا حساباتنا:-قناة ألعاب الرئيسية:https://www.youtube.com/c/alaabgamingصفحة البودكاست الصوتيhttp://alaab.buzzsprout.comتويتر ألعاب: (@AlaabGaming)http://www.twitter.com/AlaabGamingانستجرام ألعاب: (@AlaabGaming)http://www.instagram.com/alaabgamingقناة ألعاب للبث المباشر في تويتش:http://www.twitch.tv/AlaabLIVEتابعوا قناة خالد العوبثاني في تويتش:https://www.twitch.tv/shaggiekayتابعوا عمران الحازمي على قناته في تويتش (18+):https://www.twitch.tv/abu_maryam==================================================موسيقات الحلقة:-المقدمةAlaab Network - A Beautiful Day To Play ~Alaab Main Theme~Publisher: Ahmed AlrashedComposer: Tee LopesالنهايةGran Turismo 5 - Love & PeacePublisher: SonyMusic: Masahiro Andoh, KEMMEI, Maki Mannami, Yuto Takei, MAKOTO, Nittoku Inoue, Ryo Sonoda, Yuki Oike, Satoshi Bandoh, Yudai Sato, aM™[aem], YO-C+B.U.S, Gonno, daiki kasho, Taku Yabuki, Norihito Sumitomo, Seigen Tokuzawa, Taroma Koshida, Keiji Inai, Daisuke Kawai, Akihisa Yamaguchi
While working as a gas controller in corporate America for TransCanada in Houston, Chad Price discovered that corporate America wasn't sustainable for him long term and he wanted to start his own business. Seeing the inner workings of a large corporation gave him the impetus to start his own e-commerce focused business. Along with two partners, they narrowed down their product list and settled on kettlebells. At the time, it wasn't a known space but was a growing market. He desired to build kettlebells as the centerpiece of a health and wellness community and started the first BIPOC owned Kettlebell company, “Kettlebell Kings” which is like the ESPN of the kettlebell world; a place to foster a community of people using kettlebells as the centerpiece of fitness; take everyone's content alongside their uniquely created content and display it in a way that's easy for people to consume and feel part of a community. In business, he can be as competitive as he wants and not worry like he did on the sports field, when he was at Rice University. After ten years, Chad's first venture Kettlebell Kings was acquired by Razor Group for millions of dollars. He then went on to create and start “Life Grows Green” as a side project that he started as a result of negative images and culture around hemp plants. Being a big believer in natural and green products which is naturally encompassed in Hemp, he tried to make products just from natural based products. Products include CBD related capsules, oils, tinctures, salves, peanut butter, honey, melatonin and protein powder and LGG has made them available direct to the online consumer. Chad continues his commitment to fitness, health and wellness and makes sure to travel extensively and spend time with his family. In addition to listening to the episode, you can watch a video of their discussion on our YouTube Channel. And be sure to subscribe to support the podcast! For general information about the podcast, send an email to info@beinhakerlaw.com To follow Mitch and the podcast, go to linktr.ee/beinhakerlaw. You can subscribe and listen to episodes on Apple Podcasts, Google Podcasts, Amazon Music, Spotify and most other directories. Please review us whenever possible and thanks for your continued support! Sponsorships and paid guest appearances are available. Connect with us by email or on social media. The Accidental Entrepreneur is brought to you with the help of our sponsor, AWeber - the world's leading small business email marketing and automation service provider. Since 1998, AWeber has helped more than 1 million small businesses, entrepreneurs through its suite of web-based email marketing, automation tools and education. AWeber – the best option when it comes to marketing your business. Visit http://bit.ly/3HK3DVB for more information and to sign up for a trial account. We are also brought to you by TAB. Since 1989, The Alternative Board (or TAB) has been one of the leading peer advisory and business coaching organizations for independent business owners and CEOs across the world. By facilitating peer advisory boards, private 1-on-1 coaching and strategic planning services, TAB helps business owners improve their businesses in ways that change their lives. https://www.thealternativeboard.com/jersey-shore-north Also brought to you by Beinhaker Law, a boutique business & estates legal practice in Clark, NJ. To learn about shared outside general counsel services and how to better protect your business, visit https://beinhakerlaw.com/fractional-gen-counsel/ Opening music written and performed by Howie Moscovitch and Made to Order Music. For more information about Howie and his music services, visit https://howiemoscovitch.com/made-to-order-music/ Please support our affiliate sponsor (https://beinhakerlaw.com/podcast-affiliates/) One of One Productions - a New Jersey-based studio, just over the George Washington bridge, that caters to the booming business of podcasting. Be sure to check out the guesting kit that they've created exclusively for our listeners! https://one-of-one-productions.myshopify.com/products/mitchell-beinhakers-guesting-kit Also, support the show and get your own podcast merch! (https://beinhakerlaw.com/podcast-store/) The Accidental Entrepreneur is a trademark of Mitchell C. Beinhaker. Copyright 2018-2023. All rights reserved.
A long-running LGG inside joke was recently killed by the Supreme Court. Why can't we have fun things? Check out our prior episode about this case: https://soundcloud.com/user-329223368/s05e06-long-live-the-warhol-rule
Welcome to Part 2 of our Enlarged Tonsils and Adenoids series in which we will be answering all your questions about this very popular topic. If you missed Part 1, be sure to listen to it first as it contains a lot of information, including our holistic approach on how to treat enlarged tonsils and adenoids - click here to listen.In today's episode, I'm answering some of the questions that came through from our Instagram community including:Do probiotics help reduce enlarged tonsils and adenoids?Is there a link to food intolerances?How can the diet help?Does my child mouth breathe because of enlarged tonsils and adenoids? Natural remedies to reduce the size of the tonsils and adenoids.Is there a link to strep throat?What causes tonsils and adenoids to become enlarged?What are some post-surgery nat remedies?When should I stop trying to shrink naturally and opt for surgery?Is surgery really necessary?Episode Links:Episode 115: An alternative approach to enlarged tonsils and adenoids.Episode 10: Probiotics for kids - Do we need them?Episode 18: All about dairy - Is dairy a problem for your child.Do you have a child that needs help with enlarged tonsils and adenoids - Book an appointment here.
حلقة جديدة من بودكاست ديوانية LGG – 25/07/2022 – تكلمنا فيها عن ألعاب كثيرة وأبرز الأخبار
حلقة جديدة من بودكاست ديوانية LGG – 18/06/2022 – تكلمنا فيها عن ألعاب كثيرة وأبرز الأخبار الحضور: عبدالله “بيشو” بوشهري طلال السعيدي يعقوب الحسيني عادل بارودي 00:00 المقدمة 03:22 نشاطات الفريق 16:30 انطباعات طلال الكاملة بعد تختيم لعبة Card Shark 25:50 انطباعات بيشو للعبة Neo: The World Ends With You 32:35 انطباعات أولية للعبة Mario
LGG #بودكاست #العاب حلقة دوانية إل جي جي : غودزيلا تحسف جدتم باتمانحلقة جديدة من بودكاست ديوانية LGG – 30/05/2022 – تكلمنا فيها عن ألعاب كثيرة وأبرز الأخبار الحضور:عبدالله “بيشو” بوشهري – @BashaBeshoطلال السعيدي – @Talal_Alsaeediيعقوب الحسيني – @yaqoub_hعلي الدهيش – @ZENGA83عادل البارودي – @Justice_TG 00:00 المقدمة02:10 آخر نشاطات الفريق24:15 انطباعات بيشو النهائية بعد تختيم
Natural compound in basil may protect against Alzheimer's disease pathology University of South Florida, October 5, 2021 Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer's disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests. The new study published Oct. 5 in the Frontiers in Aging Neuroscience, discovered a sensing mechanism associated with the gut microbiome that explains how fenchol reduces neurotoxicity in the Alzheimer's brain. Emerging evidence indicates that short-chain fatty acids (SCFAs)– metabolites produced by beneficial gut bacteria and the primary source of nutrition for cells in your colon—contribute to brain health. The abundance of SCFAs is often reduced in older patients with mild cognitive impairment and Alzheimer's disease, the most common form of dementia. However, how this decline in SCFAs contributes to Alzheimer's disease progression remains largely unknown. Gut-derived SCFAs that travel through the blood to the brain can bind to and activate free fatty acid receptor 2 (FFAR2), a cell signaling molecule expressed on brain cellscalled neurons. "Our study is the first to discover that stimulation of the FFAR2 sensing mechanism by these microbial metabolites (SCFAs) can be beneficial in protecting brain cells against toxic accumulation of the amyloid-beta (Aβ) protein associated with Alzheimer's disease," said principal investigator Hariom Yadav, Ph.D., professor of neurosurgery and brain repair at the USF Health Morsani College of Medicine, where he directs the USF Center for Microbiome Research. One of the two hallmark pathologies of Alzheimer's disease is hardened deposits of Aβ that clump together between nerve cells to form amyloid protein plaques in the brain. The other is neurofibrillary tangles of tau protein inside brain cells. These pathologies contribute to the neuron loss and death that ultimately cause the onset of Alzheimer's, a neurodegenerative disease characterized by loss of memory, thinking skills and other cognitive abilities. Dr. Yadav and his collaborators delve into molecular mechanisms to explain how interactions between the gut microbiome and the brain might influence brain health and age-related cognitive decline. In this study, Dr. Yadav said, the research team set out to uncover the "previously unknown" function of FFAR2 in the brain. The researchers first showed that inhibiting the FFAR2 receptor (thus blocking its ability to "sense" SCFAs in the environment outside the neuronal cell and transmit signaling inside the cell) contributes to the abnormal buildup of the Aβ protein causing neurotoxicity linked to Alzheimer's disease. Then, they performed large-scale virtual screening of more than 144,000 natural compounds to find potential candidates that could mimic the same beneficial effect of microbiota produced SCFAs in activating FFAR2 signaling. Identifying a natural compound alternative to SCFAs to optimally target the FFAR2 receptor on neurons is important, because cells in the gut and other organs consume most of these microbial metabolites before they reach the brain through blood circulation, Dr. Yadav noted. Dr. Yadav's team narrowed 15 leading compound candidates to the most potent one. Fenchol, a plant-derived compound that gives basil its aromatic scent, was best at binding to the FFAR's active site to stimulate its signaling. Further experiments in human neuronal cell cultures, as well as Caenorhabditis (C.) elegans (worm) and mouse models of Alzheimer's disease demonstrated that fenchol significantly reduced excess Aβ accumulation and death of neurons by stimulating FFAR2 signaling, the microbiome sensing mechanism. When the researchers more closely examined how fenchol modulates Aβ-induced neurotoxicity, they found that the compound decreased senescent neuronal cells, also known as "zombie" cells, commonly found in brains with Alzheimer's disease pathology. Zombie cells stop replicating and die a slow death. Meanwhile, Dr. Yadav said, they build up in diseased and aging organs, create a damaging inflammatory environment, and send stress or death signals to neighboring healthy cells, which eventually also change into harmful zombie cells or die. "Fenchol actually affects the two related mechanisms of senescence and proteolysis," Dr. Yadav said of the intriguing preclinical study finding. "It reduces the formation of half-dead zombie neuronal cells and also increases the degradation of (nonfunctioning) Aβ, so that amyloid protein is cleared from the brain much faster." Before you start throwing lots of extra basil in your spaghetti sauce or anything else you eat to help stave off dementia, more research is needed—including in humans. In exploring fenchol as a possible approach for treating or preventing Alzheimer's pathology, the USF Health team will seek answers to several questions. A key one is whether fenchol consumed in basil itself would be more or less bioactive (effective) than isolating and administering the compound in a pill, Dr. Yadav said. "We also want to know whether a potent dose of either basil or fenchol would be a quicker way to get the compound into the brain." Researchers find sense of purpose associated with better memory Florida State University, October 6, 2021 Add an improved memory to the list of the many benefits that accompany having a sense of purpose in life. A new study led by Florida State University researchers showed a link between an individual's sense of purpose and their ability to recall vivid details. The researchers found that while both a sense of purpose and cognitive function made memories easier to recall, only a sense of purpose bestowed the benefits of vividness and coherence. The study, which focused on memories related to the COVID-19 pandemic, was published in the journal Memory. "Personal memories serve really important functions in everyday life," said Angelina Sutin, a professor in the College of Medicine and the paper's lead author. "They help us to set goals, control emotions and build intimacy with others. We also know people with a greater sense of purpose perform better on objective memory tests, like remembering a list of words. We were interested in whether purpose was also associated with the quality of memories of important personal experiences because such qualities may be one reason why purpose is associated with better mental and physical health." Nearly 800 study participants reported on their sense of purpose and completed tasks that measured their cognitive processing speed in January and February 2020, before the ongoing coronavirus pandemic took hold in the U.S. Researchers then measured participants' ability to retrieve and describe personal memories about the pandemic in July 2020, several months into the public health crisis. Participants with a stronger sense of purpose in life reported that their memories were more accessible, coherent and vivid than participants with less purpose. Those with a higher sense of purpose also reported many sensory details, spoke about their memories more from a first-person perspective and reported more positive feeling and less negative feeling when asked to retrieve a memory. The researchers also found that depressive symptoms had little effect on the ability to recall vivid details in memories, suggesting that the connection between life purpose and memory recall is not due to the fewer depressive symptoms among individuals higher in purpose. Purpose in life has been consistently associated with better episodic memory, such as the number of words retrieved correctly on a memory task. This latest research expands on those connections to memory by showing a correlation between purpose and the richness of personal memory. "We chose to measure the ability to recall memories associated with the COVID-19 pandemic because the pandemic is an event that touched everyone, but there has been a wide range of experiences and reactions to it that should be apparent in memories," said co-author Martina Luchetti, an assistant professor in the College of Medicine. Along with the association with better memory, previous research has found other numerous benefits connected with having a sense of purpose, from a lower risk of death to better physical and mental health. "Memories help people to sustain their well-being, social connections and cognitive health," said co-author Antonio Terracciano, a professor in the College of Medicine. "This research gives us more insight into the connections between a sense of purpose and the richness of personal memories. The vividness of those memories and how they fit into a coherent narrative may be one pathway through which purpose leads to these better outcomes. Vitamin D protects against severe asthma attacks Queen Mary University of London, October 3, 2021 Taking oral vitamin D supplements in addition to standard asthma medication could halve the risk of asthma attacks requiring hospital attendance, according to research led by Queen Mary University of London (QMUL). Asthma affects more than 300 million people worldwide and is estimated to cause almost 400,000 deaths annually. Asthma deaths arise primarily during episodes of acute worsening of symptoms, known as attacks or 'exacerbations', which are commonly triggered by viral upper respiratory infections. Vitamin D is thought to protect against such attacks by boosting immune responses to respiratory viruses and dampening down harmful airway inflammation. The new study, funded by the National Institute for Health Research, and published in The Lancet Respiratory Medicine, collated and analysed the individual data from 955 participants in seven randomised controlled trials, which tested the use of vitamin D supplements. Overall, the researchers found that vitamin D supplementation resulted in: a 30 per cent reduction in the rate of asthma attacks requiring treatment with steroid tablets or injections - from 0.43 events per person per year to 0.30. a 50 per cent reduction in the risk of experiencing at least one asthma attack requiring Accident and Emergency Department attendance and/or hospitalisation - from 6 per cent of people experiencing such an event to 3 per cent. Vitamin D supplementation was found to be safe at the doses administered. No instances of excessively high calcium levels or renal stones were seen, and serious adverse events were evenly distributed between participants taking vitamin D and those on placebo. Lead researcher Professor Adrian Martineau said: "These results add to the ever growing body of evidence that vitamin D can support immune function as well as bone health. On average, three people in the UK die from asthma attacks every day. Vitamin D is safe to take and relatively inexpensive so supplementation represents a potentially cost-effective strategy to reduce this problem." The team's use of individual participant data also allowed them to query the extent to which different groups respond to vitamin D supplementation, in more detail than previous studies. In particular, vitamin D supplementation was found to have a strong and statistically-significant protective effect in participants who had low vitamin D levels to start with. These participants saw a 55 per cent reduction in the rate of asthma exacerbations requiring treatment with steroid tablets or injections - from 0.42 events per person per year to 0.19. However, due to relatively small numbers of patients within sub-groups, the researchers caution that they did not find definitive evidence to show that effects of vitamin D supplementation differ according to baseline vitamin D status. Professor Hywel Williams, Director of the NIHR Health Technology Assessment Programme, said: "The results of this NIHR-funded study brings together evidence from several other studies from over the world and is an important contribution to reducing uncertainties on whether Vitamin D is helpful for asthma - a common condition that impacts on many thousands of people worldwide." Dr David Jolliffe from QMUL, first author on the paper, added: "Our results are largely based on data from adults with mild to moderate asthma: children and adults with severe asthma were relatively under-represented in the dataset, so our findings cannot necessarily be generalised to these patient groups at this stage. Further clinical trials are on-going internationally, and we hope to include data from them in a future analysis to determine whether the promise of today's results is confirmed in an even larger and more diverse group of patients." Study Shows Lifestyle Choices Have Significant Impact on Multiple Chronic Conditions, Significant Implications For Reducing Costs Yale University, October 05, 2021 In a study published in the Journal of Preventive Medicine, Adams and colleagues showed a linear association between a number of modifiable risk factors and multiple chronic conditions, making those modifications a key to health care cost savings and to preventing a wide range of conditions. The data analyzed for the study, https://authors.elsevier.com/a/1VpFeKt2pmc9H, were from the publicly available 2013 Behavioral Risk Factor Surveillance System and included 483,865 non-institutionalized US adults ages 18 years old or older. Chronic conditions included asthma, arthritis, heart disease, stroke, chronic obstructive pulmonary disease (COPD), cognitive impairment, cancer other than skin, and kidney disease. Risk factors included obesity, current smoking, sedentary lifestyle, inadequate fruit and vegetable consumption and sleeping other than seven to eight hours, while depression, hypertension, high cholesterol, and diabetes were considered in each category. Previous research by Thorpe and colleagues had estimated that the care of adults with four or more chronic conditions (17.1% of all adults in the study) is responsible for 77.6% of all health care costs in the U.S. today. The potential savings by reducing just two risk factors (diabetes and hypertension) and their related comorbidity was estimated previously by Ormond and colleagues at $9 billion annually over one to two years and closer to $25 billion a year after 5 years or more, factoring in possible complications. True Health Initiative founder, at Yale University Director and study co-author David L. Katz, MD, MPH, FACLM, pointed out that in addition to costs, another implication of the study results is an individual's access to healthcare if they have one or more of the chronic conditions. "Although insurers decide what qualifies as a pre-existing condition, all the chronic conditions used in this study except cognitive impairment are commonly included," he said. "Individuals with a pre-existing condition could be denied coverage or face higher premiums. While having a pre-existing condition might not affect coverage for adults eligible for Medicare, over half of all adults with multiple chronic conditions are ages 18 to 64 years." American College of Lifestyle Medicine President George Guthrie, MD, MPH, FACLM, said the study confirms the necessity for addressing the root cause of chronic conditions. "The evidence shows that the risks for chronic disease are rooted in lifestyle choices," he said. "More than ever, it is important to emphasize lifestyle medicine as the first treatment option for preventing, treating, and in some cases, reversing the cause of chronic conditions. If we can help people with chronic conditions, we can add years to their life and life to their years, as well as lower the ever-increasing costs of healthcare for everyone." Physical athletes' visual skills prove sharper than action video game players University of Waterloo (Canada), October 7, 2021 Athletes still have the edge over action video gamers when it comes to dynamic visual skills, a new study from the University of Waterloo shows. For an athlete, having strong visual skills can be the difference between delivering a peak performance and achieving average results. "Athletes involved in sports with a high-level of movement—like soccer, football, or baseball—often score higher on dynamic visual acuity tests than non-athletes," said Dr. Kristine Dalton of Waterloo's School of Optometry & Vision Science. "Our research team wanted to investigate if action video gamers—who, like e-sport athletes, are regularly immersed in a dynamic, fast-paced 2D video environment for large periods of time—would also show superior levels of dynamic visual acuity on par with athletes competing in physical sport." While visual acuity (clarity or sharpness of vision) is most often measured under static conditions during annual check-ups with an optometrist, research shows that testing dynamic visual acuity is a more effective measure of a person's ability to see moving objects clearly—a baseline skill necessary for success in physical and e-sports alike. Using a dynamic visual acuity skills-test designed and validated at the University of Waterloo, researchers discovered that while physical athletes score highly on dynamic visual acuity tests as expected, action video game players tested closer to non-athletes. "Ultimately, athletes showed a stronger ability to identify smaller moving targets, which suggests visual processing differences exist between them and our video game players," said Alan Yee, a Ph.D. candidate in vision science. All participants were matched based on their level of static visual acuity and refractive error, distinguishing dynamic visual acuity as the varying factor on their test performance. These findings are also important for sports vision training centers that have been exploring the idea of developing video game-based training programs to help athletes elevate their performance. "Our findings show there is still a benefit to training in a 3D environment," said Dalton. "For athletes looking to develop stronger visual skills, the broader visual field and depth perception that come with physical training may be crucial to improving their dynamic visual acuity—and ultimately, their sport performance." The study, Athletes demonstrate superior visual dynamic visual acuity, authored by Waterloo's School of Optometry & Vision Science's Dalton, Yee, Dr. Elizabeth Irving and Dr. Ben Thompson, was recently published in the journal Optometry and Vision Science. Probiotic Akkermansia muciniphila and environmental enrichment reverse cognitive impairment associated with high-fat high-cholesterol consumption University of Oviedo (Spain), September 8, 2021 Nonalcoholic steatohepatitis (NASH) is one of the most prevalent diseases globally. A high-fat, high-cholesterol (HFHC) diet leads to an early NASH model. It has been suggested that gut microbiota mediates the effects of diet through the microbiota–gut–brain axis, modifying the host's brain metabolism and disrupting cognition. Here, we target NASH-induced cognitive damage by testing the impact of environmental enrichment (EE) and the administration of either Lacticaseibacillus rhamnosus GG (LGG) or Akkermansia muciniphila CIP107961 (AKK). EE and AKK, but not LGG, reverse the HFHC-induced cognitive dysfunction, including impaired spatial working memory and novel object recognition; however, whereas AKK restores brain metabolism, EE results in an overall decrease. Moreover, AKK and LGG did not induce major rearrangements in the intestinal microbiota, with only slight changes in bacterial composition and diversity, whereas EE led to an increase in Firmicutes and Verrucomicrobia members. Our findings illustrate the interplay between gut microbiota, the host's brain energy metabolism, and cognition. In addition, the findings suggest intervention strategies, such as the administration of AKK, for the management of the cognitive dysfunction related to NASH. In this study, we described cognitive, brain metabolism, and microbiota alterations associated with high-fat and high-cholesterol consumption. In addition, we clearly showed that environmental enrichment and A. muciniphila CIP107961 restore cognitive dysfunction. Furthermore, we revealed that cognitive improvement is associated with differential effects of environmental enrichment and this strain of A. muciniphila on brain metabolism and gut microbiota. Finally, we discovered that restored cognitive function was associated with the administration of A. muciniphila CIP107961, but not L. rhamnosus GG, which may be clinically relevant when selecting probiotics for treating HFHC-derived pathologies. In conclusion, the microbiota and cognition are intimately connected through the gut–brain axis, and in HFHC pathologies they can be influenced by environmental enrichment and A. muciniphila CIP107961 administration. Cognitive improvement was accompanied by changes in brain metabolic activity and gut microbial composition analysis, pointing to specific microbiota targets for intervention in diet-induced pathologies. However, some mechanisms other than major changes in microbiota composition and the combined effect of environmental enrichment and A. muciniphila administration, which we identified in this study, may also be biologically relevant and will need to be investigated in future studies due to their relative contributions to the selection of effective treatments for patients.
حلقة جديدة من بودكاست ديوانية LGG – 27/09/2021 – تكلمنا فيها عن ألعاب كثيرة وأبرز الأخبار الحضور: عبدالله بوشهري طلال السعيدي حمد الحميدة عادل البارودي يعقوب الحسيني 00:00 المقدمة 00:50 آخر نشاطات الفريق 06:15 انطباعات بيشو الكاملة عن لعبة Wario Ware Get It Together 18:25 تكملة انطباعات طلال و بيشو عن لعبة Tales of Arise
راعي الحلقة: STC Playلكل المهتمين بالقيمنق هذا مكانكم!منصة stc play هي أكبر تجمع للقيمرز والمهتمين بعالم الألعاب فيها بطولات لأشهر وأقوى الألعاب وجوائز مالية وأكثر! سجّل فيها الآن مجانًا واستمتع بالمميزات المتنوعة!روابط التسجيل:-التطبيق:https://app.adjust.com/7hkcru5الموقع:https://app.adjust.com/6atohig?engagement_type=fallback_click&redirect=https%3A%2F%2Fstcplay.gg%2Fhome%3Futm_source%3Dinfluencer_Alaab_Podcast%26utm_medium%3Dcpc%26utm_campaign%3DGamers_Influencers_Campaign_June_2021==================================================في هذه الحلقة تكلّمنا عن انطباعاتنا للعبةScarlet Nexus و GPD WIN 3بالإضافة الى أخبار ناقشناها مثل الاعلان عنSwitch OLED Modelوغيره!ألعاب تكلمّنا عنها وبالترتيب:Darksiders Genesis Scarlet Nexus Pokemon Trading Card Game 2: The Invasion of Team GR!FINAL FANTASY XIV: A Realm Rebornجهاز GPD WIN 3Need for Speed Hot Pursuit Remasteredالحضور:فهد يوسفأحمد الراشدعادل باجنيدعمران الحازميخالد العوبثاني00:00 - المقدمة 12:55 - Darksiders Genesis24:27 - SCARLET NEXUS42:35 - Pokémon Trading Card Game 2: The Invasion of Team GR!50:51 - FINAL FANTASY XIV Online57:00 - استعراض جهاز GPD WIN31:08:23 - Need for Speed Hot Pursuit Remastered1:16:59 - نهاية الفقره .. او لا ؟1:18:36 - شباب LGG معلقين في بطولة TEKKEN 71:21:28 - نينتيندو سويتش الجديد1:31:59 - اميبو يعطيك قدرة مهمة بداخل اللعبه؟!1:35:29 - بلاستيشن ستايت اوف بلاي واخبار اخرى1:47:05 - اعلان عن عرض لديستني 21:47:27 - اخبار متفرقة عن ويتشر 31:49:38 - اساسين كريد اينفينيتي 1:52:25 - استوديو لفل 5 ومشروع جديد1:53:01 - مايكروسوفت ودارك سولز 3 1:54:38 - اعلان عن فيفا 22 اليوم او امس او بكره1:55:15 - فريق بوبلر وسايلنت هيل1:55:55 - حدث جديد لايبكس ليجيند1:56:11 - مبيعات ريزيدنت ايفل فيليج1:57:09 - نسخة نادرة للعبة NES بيعت برقم قياسي1:58:55 - هاشتاق ألعاب!!==================================================تابعوا حساباتنا:-قناة ألعاب الرئيسية:https://www.youtube.com/c/alaabgamingصفحة البودكاست الصوتيhttp://alaab.buzzsprout.comتويتر ألعاب: (@AlaabGaming)http://www.twitter.com/AlaabGamingانستجرام ألعاب: (@AlaabGaming)http://www.instagram.com/alaabgamingتابعوا عمران الحازمي على قناته في تويتش (18+):https://www.twitch.tv/abu_maryamقناة ألعاب للبث المباشر في تويتش:http://www.twitch.tv/AlaabLIVE==================================================موسيقات الحلقة:-Alaab Network - A Beautiful Day To Play ~Alaab Main Theme~Publisher: Ahmed AlrashedComposer: Tee LopesPokemon TCG - Ronald's ThemePublisher: GameFreakComposer: Ichirō Shimakura
We are covering quite a different and specific topic today on the podcast, epilepsy in kids. Although this may not be a common issue for most parents, my hope is that what we talk about today will be shared and passed onto those families needing this kind of information and advice.Sonya Reynolds is a Nutritionist and Life Coach with over 15 years of experience in the natural health profession and in this episode, Sonya shares her personal journey with her daughter's epilepsy and how she used complementary therapies and nutrition to help improve her symptoms. Listen in as she discusses more info on:> What epilepsy is, the most common types and its effect on the brain> How nutrition plays a role in supporting kids with epilepsy and the benefits of diets that are gluten-free, allergen-free, as well as the effect of modified Atkins diet on seizures> Common medications that are prescribed for epilepsy, how they work in the body, and some of the side effects> Essential nutrients and supplementation of B vitamins, folate, zinc and magnesium to support epileptic kids> The importance of using probiotics, specifically lactobacillus rhamnosus LGG to support kids' microbiomes and help with allergies and food intolerances> How exercise and physiotherapy can help manage side effects from conventional epilepsy medication> Exploring all options like medical Cannabis to support kids with epilepsy, finding the right people for support and more!Episode Links:Find out more about Sonya at https://www.studio-you.com.au/sonya-reynolds/
Por fin con Manolo de el corillo de LGG
LGG discusses sex at construction site, possibility of a new kink, and she tells three hoe stories for the price of one. Follow me on all socials at DespicableT_ --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/tklorenz/message Support this podcast: https://anchor.fm/tklorenz/support
At long last, LGG dives into the background and history of the net neutrality debate to discuss common carriers how Internet services have been historically regulated, and Ben finally explains his remarks from prior episodes about why the sinking of the Titanic teaches us important lessons about net neutrality.
Today, we're going to be talking about one of the questions that I commonly get asked as a Naturopath, and that is, probiotics - do my kids need them? And if so, which ones should I be giving them? As I mentioned in previous episodes, there are three main ways that we can top up that healthy beneficial bacteria in our kids' gut microbiome: eating fermented foods, environmental exposure to microbes and probiotic supplements, which is what we're going to focus on today. I'll be talking in-depth about certain strains of good bacteria and what they can do to help our kids' health, such as:Lactobacillus rhamnosus LGG – to help improve allergic toleranceLactobacillus acidophilus NCFM and Bifidobacterium – to reduce pain and bloating in the gut, for boosting immunity and restoring gut health after antibiotic useSaccharomyces boulardii – to balance gut flora and address conditions of overgrowthEpisode Links:Save your FREE seat for the 3 Surprisingly Simple Ways to Transform your Kids' Gut Health Masterclass Get on the waitlist for the Natural Super Kids KLUBBook an appointment with our Naturopath Check out the Kultured Wellness starter cultures
Expandiendo horizontes!! LGG les presenta este nuevo podcast exclusivamente de gaming y venimos fuerte en el primero episodio. Hablamos del season nuevo por venir de Apex Legends, el nuevo character y arma. Los problemas dentro del juego de Harry Potter, God of War. También hablamos de las últimas noticias en el mundo de Pokemon y clasificamos de peor a mejor todos los grass type starters del juego. Enjoy!!! Síguenos en nuestras redes: Facebook: https://www.facebook.com/gaming/LGGPFR/ Instagram: https://www.instagram.com/lggpfr/ Track: Intro for a nonexisting video game Artist: Captive Portal Download: https://freemusicarchive.org/music/Captive_Portal/Laughing_Turkeys_-_EP/01_Intro_For_A_Nonexisting_Video_Game
حلقة جديدة من بودكاست ديوانية LGG – 16/11/2020 – تكلمنا فيها عن ألعاب كثيرة و آخر الأخبار الي نهتم فيها الحضور: يعقوب الحسيني عبدالله بوشهري طلال السعيدي عادل بارودي التسلسل الزمني: 00:00 المقدمة + تجربتنا لجهاز Xbos Series X 28:00 سوالف عامة 31:45 لعبة Ori and The Will of The Wisps 34:15 لعبة Pikmin 3
We're making picks for week 12! Phillip is joined by our usual pickers Daniel Alexander of Grinders with Blinders and Chris Ross of the LGG, plus a special guest picker since it's a light week; Chase Kiddy! Betting a Draft. (02:38) Texas vs Kansas. Yes we know it's been delayed. (05:50) Iowa State vs Kansas State (11:22) Oklahoma vs Oklahoma State (19:22) Non-Big 12 Picks (27:15) Follow us on Twitter and Instagram. Save 20% on your first order at Homefield Apparel with promo code TEN12. Save 10% on your order at Lazy Fair Coffee with promo code Ten12. Leave us 5 stars and a review please, it helps the show out! --- Send in a voice message: https://anchor.fm/ten12-podcast/message
Can receiving all posttransplant care at home benefit patients undergoing hematopoietic stem cell transplant (HSCT)? Researchers are conducting phase 2 trials to find out. Anthony D. Sung, MD, of Duke University School of Medicine, described this research to host David H. Henry, MD. Dr. Sung outlined the process of receiving post-HSCT care at home and discussed Duke's clinical trials assessing the impact of home care on costs, quality of life, the microbiome, and graft-versus-host disease (GVHD). Dr. Sung also discussed another Duke trial investigating whether a probiotic can prevent COVID-19. Post-HSCT care at home: How it works Cell collection (if applicable), conditioning, and HSCT all take place in the outpatient setting. From day 1 after transplant onward, the patient receives all care at home. A nurse practitioner or physician assistant visits the patient every morning to draw labs, which are run at the hospital. A nurse visits every afternoon to give the patient supportive care. Patients are given the tools to video chat with physicians. Patients must live within 1 hour of Duke’s transplant center or relocate to furnished apartments near the transplant center. Phase 1 trial: Feasible and safe Dr. Sung and colleagues have completed a phase 1 trial, which suggested that post-HSCT care at home was feasible and safe. Outcomes were similar to outcomes in patients who do not receive post-HSCT care at home. The results were presented at ASH 2017 (Blood. 2017;130:745; https://bit.ly/2UelgVo). Phase 2 trials: Microbiome, GVHD, and other outcomes With one phase 2 trial (NCT01725022), Dr. Sung and colleagues aim to determine if: Patients can maintain their normal bowel microbiota by receiving post-HSCT care at home, as opposed to outpatient or inpatient care. Treatment-related morbidities and mortality are similar between the groups. Care at home improves quality of life and reduces costs. Trial details can be found here: https://bit.ly/2JRnY0Y. In the other phase 2 trial (NCT02218151), the main goal is to compare the incidence of grade 2-4 acute GVHD at 6 months in patients receiving care at home vs. inpatient or outpatient care. The theory is that maintaining the microbiome will reduce the risk of GVHD. A case of GVHD can add $100,000 to the cost of care, Dr. Sung noted. Trial details can be found here: https://bit.ly/32vr8y3. COVID-19 and the microbiome Dr. Sung and colleagues are also conducting a trial of Lactobacillus rhamnosus GG (LGG) as prophylaxis for COVID-19 (NCT04399252). Research has shown that giving LGG to mice with Pseudomonas aeruginosa pneumonia can: Help prevent lung injury and significantly improve survival (Shock. 2013;40[6]:496-503; https://bit.ly/3khQBRr). Help modulate the microbiome and immune system, leading to decreased inflammation, TNF-alpha, IL-2, and IL-6, as well as increased regulatory T cells (Clin Nutr. 2017;36[6]:1549-1557; https://bit.ly/35lENJZ). Dr. Sung noted that TNF-alpha, IL-2, and IL-6 have also been implicated in COVID-19 and associated with increased lung injury. Dr. Sung and colleagues have theorized that LGG could decrease lung injury and the symptoms of COVID-19 and perhaps even prevent COVID-19. The researchers are conducting a randomized trial of LGG in household contacts of patients with COVID-19 (https://bit.ly/2GRSC9x). For more details on the trial, email protect-eha@duke.edu or visit https://bit.ly/2IsLjWh. Disclosures: Dr. Sung and Dr. Henry have no relevant disclosures. Duke's transplant trials are funded by grants from the National Institutes of Health. Funding for the COVID-19 trial is provided by the Duke Microbiome Center and philanthropic giving. The LGG and placebo used in the trial are provided by DSM. * * * For more MDedge podcasts, visit mdedge.com/podcasts Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgehemonc David Henry on Twitter: @davidhenrymd
We're making picks all season long! Phillip is joined by Chris Ross of the LGG and Daniel Alexander of Grinders with Blinders for the first picks episode of the season. We're making picks on: Texas vs. UTEP Kansas vs. Coastal Carolina Kansas State vs. Arkansas State Iowa State vs. Louisiana And three other games of our choosing! Plus, Daniel makes his pick for the Big 12 champ and a couple extra bets for Premier League and the NFL's opening weekends! Save 20% on your first purchase at Homefield Apparel with the promo code TEN12. Save 10% off your order at Lazy Fair Coffee with the promo code Ten12. Follow us on Twitter and Instagram. Leave us 5-stars and a review! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app
We have actual kick-off times for the start of the Big 12 season! Phillip breaks those down, including his one problem with them. Then, we welcome Scott Wright of the Oklahoman to the show for our Oklahoma State season preview. We discuss the tumultuous summer, offensive line concerns, back-up running backs, Spencer Sanders' relationship with his new quarterback coach, and more! Order from Lazy Fair Coffee and save 10% with the promo code Ten12. Follow us on Twitter and Instagram. Please leave a 5-star rating and a review. Visit the mothership, The LGG.
Phillip gets a LOT of great stories former Kansas State offensive lineman Russ Stange on the show today. Including playing on two winless teams, the dark side of recruiting, a great Weird Rob story, and a LOT more. Check out our mothership, the LGG. Remember to leave us a 5-Star rating or review!
Lung cancer screening, Reversible Plexopathy?, LGG, ED predictors, Colorectal screening age, H. pylori family, CAR-NK cells, Thymic tumors quadshotnews@gmail.com @QuadShotNews
It's the final week of the regular season, so these are some important picks! Phillip and Chris are joined by Evan Green of the LGG this week. Picks include: Texas (-10) Texas Tech TCU (-13 1/2) WVU Baylor (-14) Kansas ISU (-5) KSU Non Big 12 (Cincinnati / Memphis, LaLa / ULM, Michigan / tOSU) Oklahoma (-13) OSU Don't forget to sign up for ESPN+ and Big 12 Now!
We are loaded with THREE INTERVIEWS today; Big 12 women's soccer with Travis Clark, men's hoops with Brian Rauf, and the latest college football playoff poll with Chris Ross. Episode includes: Share the pod with a friend! Is WVU set up for a run in the NCAA tournament? Why OSU's situation is crap in LA. Who wins this weekend. Let's Power Rank the Big 12. Why the bad bottom is good for the conference. OU is SCREWED! Baylor can't get no respect. Expansion talk (I'm sorry). Don't forget to sign up for ESPN+ Get all your Big 12 football news at the LGG.
Phillip is joined by Andy Mitts of the LGG and Joel Penfield of Cowboys Ride For Free to offer takeaways from all four Big 12 games. That includes concerns for Kansas, Kansas State, and Iowa State's offenses, is OU's defense good or not, and why Texas Tech REALLY needs Alan Bowman back quickly. Hosts Phillip Slavin and Chris Ross
Hosts Phillip and Chris are joined by Josh Cowan of the LGG to discuss their takeaways from Week 4's games. We talk ISU finding their offense and TCU's struggles on that side of the ball. Phillip and Chris get into it over the OSU / Texas game, and we find out why Baylor shouldn't schedule "off" weeks anymore. Hosts Phillip Slavin and Chris Ross
معلومات كل موسيقى وبالترتيب:- من حلقة 51:Pokemon Go - Wild EncounterPublisher: GameFreakComposer: Junichi Masuda Pokemon Go - Map Theme (FamilyJules7X Metal Cover)Publisher: GameFreakComposer: Junichi Masuda من حلقة 52:I Am Setsuna - Winter BreezePublisher: Square EnixComposer: Tomoki Miyoshi Super Mario Maker - Title ThemePublisher: NintendoComposer: Koji Kondo من حلقة 53:Undertale - Can You Really Call This A Hotel I Didn't Receive A Mint On My Pillow Or AnythingPublisher: Toby FoxComposer: Toby Fox Ori And The Blind Forest - Light of NibelPublisher: Moon StudiosComposer: Gareth Coker من حلقة 54:Gran Turismo 5 Prologue - Constructor’s BluesPublisher: SonyComposer: Masahiro Andoh Front Mission - Take The Offensive (Drammatica Orchestra Cover)Publisher: Square EnixComposer: Yoko Shimomura من حلقة 55:Abzu - Ichthyosaurus CommunisPublisher: Giant Squid StudiosComposer: Austin Wintory Super Mario World - Fortress Theme (String Quartet)Publisher: NintendoComposer: Koji Kondo من حلقة 56:Mega Man 9 - Plug ElectricPublisher: CapcomComposer: Ippo Yamada Super Mario 3D World - Sunshine SeasidePublisher: NintendoComposer: Mahito Yokota, Toru Minegishi, Yasuaki Iwata, Koji Kondo, Asuka Hayazaki, Takeshi Hama, Soyo Oka من حلقة 57:Dragon Quest IX - IntermezzoPublisher: Square EnixComposer: Koichi Sugiyama Silent Hill 2 - Promise (Reprise)Publisher: KonamiComposer: Akira Yamaoka من حلقة 58:Shingeki No Kyojin (Attack On Titan) [Anime] - Guren No YumiyaPublisher: KodanshaComposer: Hiroyuki Sawano Final Fantasy - Prelude (Distant Worlds Orchestral Cover)Publisher: Square EnixComposer: Nobuo Uematsu من حلقة 59:Sonic The Hedgehog - Green Hill Zone (“8 Bit Instrumental” Smooth Jazz Cover)Publisher: SEGAComposer: Masato Nakamura Ace Attorney 6: Spirit of Justice - Apollo Justice ~ A New Chapter of Trials!Publisher: CapcomComposer: Noriyuki Iwadare من حلقة 60:Destiny: Rise of Iron - Eyes UpPublisher: BungieComposer: Skye Lewin Ace Attorney 6: Phoenix Wright - Objection! 2016Publisher: CapcomComposer: Noriyuki Iwadare ====================================== موقع فريق LGG:http://www.luckygg.com/ قناة LGG على اليوتيوب:https://www.youtube.com/user/Luckygengamers تويتر LGG:(@luckygenGamers) https://twitter.com/luckygenGamers قناة ألعاب على اليوتيوب:http://www.youtube.com/c/AlaabGaming تويتر ألعاب:(@AlaabGaming) twitter.com/AlaabGaming
Week one is over and the Big 12 is undefeated! Phillip is joined by LGG contributors Andy Mitts and Evan Green to overreact to the Big 12's weekend with looks at Kansas, Kansas State, Texas Tech, Jalen Hurts, Texas, and whether or not the 10-0 weekend means anything. Hosts Phillip Slavin and Chris Ross Don't miss a minute of Big 12 action on ESPN+. Get signed up now!
It's a Family Affair! My very first brave Baby Boomer guest is willing to let me explore her mind, and ask ALLLLL the questions! Any advice or guidance for younger women? Auntie Gee visits The Rose Garden to talk sex, death, kids, career, and choosing happiness. #ThanksAuntie Guests: Auntie Gee, LGG
بالتعاون مع RootQuest (و LGG)، تكلّمنا عن انطباعاتنا للعبة Ace Combat و Dragon Quest 11، بالإضافة الى اخبار ناقشناها مثل آخر Nintendo Direct حق شهر سبتمبر وتجاربنا في معرض جيمرزكون جدة 2018 وغيره! نشكر House Zofi على استضافتهم لنا لتسجيل هذه الحلقة :) ألعاب تكلمّنا عنها وبالترتيب: 1- Ace Combat 7 2- Guacamelee 2 3- The Messenger 4- Spider-Man 5- Assassin’s Creed Odyssey 6- Call of Duty Black Ops 4 (Blackout Mode) 7- Dragon Quest XI الحضور: أحمد الراشد سعيد الشامسي (RootQuest) عادل بارودي (LGG) علي الدهيش (LGG) محمد الشامسي (RootQuest) زياد الحربي (RootQuest) تويتر ألعاب: (@AlaabGaming) twitter.com/AlaabGaming تويتر RootQuest: (@RootQuest) twitter.com/RootQuest تويتر LGG: (@luckygenGamers) twitter.com/luckygenGamers انستجرام ألعاب: (@AlaabGaming) instagram.com/alaabgaming قناة ألعاب في اليوتيوب YouTube youtube.com/c/alaabgaming موقع ألعاب: http://www.alaab.net تابعوا جميل عبد الأحد على قناته في تويتش: www.twitch.tv/jemimaru The Messenger - Hills of Intent (Future Autumn Hills) Publisher: Devolver Digital Composer: Eric W. Brown Dragon Quest XI - Ole! Sylvando! (Symphonic Suite Cover) Publisher: Square-Enix Composer: Koichi Sugiyama
في هذه الحلقة تكلّمنا عن انطباعاتنا للعبة Secret of Mana و Owlboy، بالإضافة الى أخبار ناقشناها مثل إعلانات الاتحاد السعودي للرياضات الإلكترونية والذهنية واضافة المنظور الأول للعبة The Evil Within 2 وغيرها! ألعاب تكلمّنا عنها وبالترتيب: - Secret of Mana - Shadow of the Colossus - Owlboy - Monster Hunter World - Celeste - Divinity Original Sin 2 الحضور: أحمد الأحمري أحمد الراشد رواح المعيقل عمر اليوسف ضيف الحلقة: عمران الحازمي تويتر ألعاب: (@AlaabGaming) twitter.com/AlaabGaming قناة ألعاب في اليوتيوب YouTube youtube.com/c/alaabgaming موقع ألعاب: www.alaab.net تابعوا جميل عبد الأحد على قناته في تويتش: www.twitch.tv/jemimaru فيديو حدث #EGA2018: https://www.youtube.com/watch?v=wpYR5v7LysU حلقة فيديوكاست LGG بمناسبة #EGA2018: https://www.youtube.com/watch?v=L7v7AGu5zZI
Are yogurt, kefir and other probiotics really good for you? Researchers at the University of California, San Francisco, believe the benefits of these products may be overstated. Michael Cabana, a professor of pediatrics, came to this conclusion while trying to figure out if a probiotic strain called LGG helps prevent the development of eczema or asthma in kids predisposed to these diseases. “At two years of age we found that there is no difference in eczema levels between the kids. Despite the fact that previous studies have shown this probiotic strain helps prevent eczema in other countries, in the San Francisco area we didn’t find the same results.” The UCSF findings further fuel the ongoing debate about the benefits of friendly bacteria in dietary supplements. “We still learned a lot from this study and we still continue following these kids. It is probably more complicated than just giving a probiotic supplement.” Genetic factors and other types of baby food, including breast milk, also affect a child’s microbiota. For Science Today, I’m Larissa Branin.
We had a great time sitting down to chat with James Walls, Rohit Sodhia, and Christi Garrett, all part of the leadership team at Lawful Good Gaming. Lawful Good Gaming is a group that brings together a community that runs a variety of RPGs online and in the person to raise money for charity. What to learn more? You can find them on Facebook, Twitter, and Google+! You can find Aser's game on October 28th here. You can read more about LGG on Gnome Stew as well! Outro Music: Port_City_Music_-_29_-_Night_Terrors from ‘Silber Sounds of Halloween' Freemusicarchive.org
اسم كل موسيقى وبالترتيب:- من حلقة 41 Chrono Cross - Dragon God Publisher: Square Enix Composer: Yasunori Mitsuda The Legend of Zelda: Ocarina of Time - Gerudo Valley Publisher: Nintendo Composer: Koji Kondo من حلقة 42 Super Mario Galaxy 2 - Throwback Galaxy Publisher: Nintendo Composer: Mahito Yokota Final Fantasy VI - Decisive Battle (SSH Cover) Publisher: Square Enix Composer: Nobuo Uematsu من حلقة 42.5 Super Mario 64 - Bob-Omb Battlefield Publisher: Nintendo Composer: Koji Kondo Final Fantasy VI - Decisive Battle Publisher: Square Enix Composer: Nobuo Uematsu من حلقة 43 Shin Onigashima - Shin Onigashima (Super Smash Bros. Brawl Arrangement) Publisher: Nintendo Composer: Koji Kondo Halo 3 - Never Forget Publisher: Microsoft Composer: Martin O'Donnell من حلقة 44 Overwatch - Main Theme Publisher: Blizzard Composer: Neal Acree Undertale - Asgore Publisher: Toby Fox Composer: Toby Fox من حلقة 45 Uncharted 2 - Nate’s Theme 2.0 Publisher: Sony Composer: Greg Edmonson Pocket Card Jockey - Yes Come On Solitaiba! Publisher: GameFreak Composer: Gō Ichinose من حلقة 46 Pokemon Blue/Red/Yellow - Viridian City Publisher: GameFreak Composer: Junichi Masuda Undertale - Heartache Publisher: Toby Fox Composer: Toby Fox من حلقة 47 Radiant Historia - Mechanical Kingdom Publisher: Atlus Composer: Yoko Shimomura Chrono Trigger - Secret of The Forest Publisher: Square Enix Composer: Yasunori Mitsuda من حلقة 48 Shovel Knight - In the Halls of the Usuper (Pridemoor Keep) Publisher: Yacht Club Games Composer: Jake Kaufman Undertale - MEGALOVANIA (insaneintherainmusic Jazz Cover) Publisher: Toby Fox Composer: Toby Fox من حلقة 49 Kid Icarus Uprising - Wrath of the Reset Bomb (Super Smash Bros. For Wii U/3DS Arrangement) Publisher: Nintendo Composer: Motoi Sakuraba Secret Of Mana - Meridian Dance Publisher: Square Enix Composer: Hiroki Kikuta من الحلقة الخاصة لمعرض E3 2016 The Legend of Zelda: Breath of the Wild - Main Theme Publisher: Nintendo Composer: Manaka Kataoka I am Setsuna - No turning back Publisher: Square Enix Composer: Tomoki Miyoshi من حلقة 50 Sonic 2 - Emerald Hill Zone (Smooth McGroove Acapella) Publisher: SEGA Composer: Masato Nakamura Touhou - U.N. Owen Was Her? (Smooth McGroove Acapella) Publisher: Team Shanghai Alice Composer: ZUN الحضور: أحمد الراشد يعقوب الحسيني عبدالله ابو شهري موقع LGG: http://www.luckygg.com/ تويتر ألعاب: (@AlaabGaming) twitter.com/AlaabGaming قناة ألعاب يوتيوب #YouTube www.youtube.com/channel/UC-yGXvmoNmOClXDOjpNQwNw
اسم كل موسيقى وبالترتيب:- من حلقة 31 Metal Gear Solid V - Paz’s Theme (Joseph Eid Acoustic Guitar Cover) Undertale - Death By Glamour من حلقة 32 Lufia 2 - Battle #2 (Arranged) Bravely Default - Depressed Land (Sinking Land) من حلقة 33 Lost Odyssey - Battle Theme Naruto Shippuden - Keisei Gyakuten (Reverse Situation) من حلقة 34 Eternal Sonata - Leap The Precipice (Battle Theme) Street Fighter V - Forgotten Waterfall من حلقة 35 Final Fantasy VI - Terra Pokemon Blue/Red/Yellow - Gym Leader Battle (Skotein Kanto Symphony) من حلقة 36 Fire Emblem: Shadow Dragons & The Blade of Light - Fire Emblem (Smash Bros. Cover) The Legend of Zelda: Twilight Princess - Hyrule Field (Orchestra) من حلقة 37 Bravely Default - You Are My Hope Undertale - Battle Against A True Hero من حلقة 38 Lufia 2 - Battle #3 (Arranged) Chrono Trigger - The Brink of Time من حلقة 39 Final Fantasy XV - Gratia Mundi [NAME NOT OFFICIAL] (Performed by GuardianSoul) Final Fantasy XV - Somnus [Instrumental] (Main Theme) من حلقة 40 Star Fox - Space Armada (Super Smash Bros. Brawl Arrangement) Final Fantasy XV - Playroom Theme الحضور: أحمد الراشد يعقوب الحسيني عبدالله ابو شهري موقع LGG: http://www.luckygg.com/ تويتر ألعاب: (@AlaabGaming) twitter.com/AlaabGaming قناة ألعاب يوتيوب #YouTube www.youtube.com/channel/UC-yGXvmoNmOClXDOjpNQwNw
اسم كل موسيقى وبالترتيب:- من حلقة 21 Ni No Kuni - Drippy ~Shizuku~ Valkyria Chronicles - Empty Loneliness (Or Empty Solitude) من حلقة 22 Mega Man 9 - Hornet Man (Hornet Dance) Bravely Default - Land of Immortality من حلقة 23 Ni No Kuni - The Hero Of The Kingdom Final Fantasy VII - Opening من حلقة 24 Super Mario RPG - Forest Maze Xenoblade Chronicles - Satorl Marsh (Night) من حلقة 25 Secret of Mana - Fear Of The Heavens The Legend of Zelda: Skyward Sword - Link's Romance من حلقة 26 Undertale - Enemy Approaching Undertale - Snowy من حلقة 27 Xenoblade Chronicles - Hometown Xenoblade Chronicles - Engage The Enemy من حلقة 28 Undertale - NGAHHH!! Undertale - Ruins من حلقة 29 Lufia 2 - Battle #1 (Arranged) Undertale - SAVE The World من حلقة 30 Chrono Trigger - Frog’s Theme (Kaeru’s Theme) The Lion King - This Land الحضور: أحمد الراشد حمد الحميدة عبدالله ابوشهري موقع LGG: http://www.luckygg.com/ تويتر ألعاب: (@AlaabGaming) twitter.com/AlaabGaming قناة ألعاب يوتيوب #YouTube www.youtube.com/channel/UC-yGXvmoNmOClXDOjpNQwNw
Cameron talks about the new X-Men movie, the mormons, the gorilla kid, stan lee hoax, and th LGG funding. Let not forget a listen left a voicemail! So if you have #AdviceForDavid make sure to tweet it to @wohlf1.
اسم كل موسيقى وبالترتيب:- من حلقة 11 Chrono Cross - Victory (Call of Summer) Final Fantasy Tactics - Painful Battle من حلقة 12 Super Mario Bros. - Overworld Theme Super Mario Bros. - Underwater Theme (Super Smash Bros. Brawl Remix) من حلقة 13 Destiny - The Traveler Metal Gear Solid V - Peace Walker (Deployment Theme) من حلقة 14 Star Wars - Main Theme Chrono Trigger - Main Theme (Orchestra) من حلقة 15 Transformers: Devastation - The Ark Minecraft - Minecraft من حلقة 16 Super Mario Galaxy 2 - The Starship Sails Xenoblade Chronicles - Colony 9 من حلقة 17 The Legend of Zelda: Triforce Heroes - Title Theme Halo: CE - Halo من حلقة 18 Pokémon TCG - Pause Menu Mega Man X - Spark Mandrill (Banjo Guy Ollie Cover) من حلقة 19 Fallout 4 - Downtown Boston Wild Arms - To A New Journey من حلقة 20 Pokémon Red/Blue/Yellow - Opening Final Fantasy VII - Fight On! الحضور: أحمد الراشد تركي الشلهوب ضيف الحلقة: يعقوب الحسيني من LGG موقع LGG: http://www.luckygg.com/ صفحة حلقة يوكو شيمومورا في موقع LGG: http://www.luckygg.com/ge_yoko-shimomura/ رابط تحميل حلقة يوكو شيمومورا: http://media.blubrry.com/luckygg/p/www.luckygg.com/podcast/GE_YokoShimomura.mp3 تويتر ألعاب: (@AlaabGaming) twitter.com/AlaabGaming قناة ألعاب يوتيوب #YouTube www.youtube.com/channel/UC-yGXvmoNmOClXDOjpNQwNw
LGG 01 - Vocabulary One of the best ways to illustrate the difficulty on translating Greek into modern English is by considering several words as representative examples. Tetelestai, which is translated as “it is finished” and teleios, which is translated “perfect”, “mature”, or “full”, are investigated in the lesson this week. Key Words Translation, vocabulary, tetelestai, teleios, teleo, oracle, finished, to fulfill, teleioo, one-to-one translation, Theology, culture, Hebraisms, perfect, mature, full, measure up, merit, meeting the highest standard, fulfill obligations, tzadik,
LGG 00 - Introduction to Greek According to Wikipedia there are 104 English translations of the full Bible. Over time the English language usage has changed just as did the Greek language. Translators must try to make the new translations relevant and are forced to choose between “formal equivalence”, which is word for word translation, or, “dynamic equivalence”, which strives to reproduce what the original audience actually heard. There are also challenges in choosing the most appropriate vocabulary word. At times there are several English words that could be selected for a given Greek word and at times the opposite is true. Additionally, there are theological or cultural concepts that have been given certain English words that may not capture the original Greek concept. And there are certain Hebrew concepts that were translated into Greek and a strict translation may not capture the original meaning. Key Words Translation, NIV, KJV, NASB, ESV, RASB, “gender-neutral”, “breathing mark”, “formal equivalence”, “dynamic equivalence”, “functional equivalence”, “paraphrase”, “man”, Robert Cawdry, extinct, extinguish, scene, Old Testament, New Testament, Septuagint, Church Fathers, Papyri, vocabulary, love, agapao, phileo, theology, baptize, paidagogos, Hebraisms, hosanna, Aramaic, “positive adjective”
في هذه الحلقة Destiny Professor Layton vs Phoenix Wright: Ace Attorney Super Smash Bros. for 3DS Demo Velocity 2X Mighty Gunvolt و المزيد ! قام بتسجيل هذه الحلقة : يعقوب الحسيني، عبدالله بوشهري، حمد الحميدة، و عادل بارودي من نحن طريقة الإشتراك بالبرنامج -ديوانية LGG : هذا البودكاست نتكلم فيه عن ما كنا نلعبه في الاسابيع الماضية. حيث يقوم
في هذه الحلقة The Last of Us Remastered Warframe JoJo’s Bizarre Adventure All-Star Battle GamesCom 2014 و المزيد ! قام بتسجيل هذه الحلقة : يعقوب الحسيني، حمد الحميدة، عادل بارودي و ضيف الحلقة بو زيد التايم لاين hh:mm:ss:اللاقرز 00:09:24شنو لعبنا 00:11:00الأخبار 01:09:50تعليقات و أسئلة المستمعين 01:49:00معلومات الموقع و اختيارنا لكم 02:28:30 من نحن طريقة الإشتراك بالبرنامج -ديوانية LGG : هذا
في هذه الحلقة Crypt of The Necrodancer Transistor Wolfenstein: The New Order Deemo Shadow Warrior Rayman Legends Destiny Beta و المزيد ! قام بتسجيل هذه الحلقة : يعقوب الحسيني، حمد الحميدة، عبدالله بوشهري، حسين الدليمي وعادل بارودي من نحن طريقة الإشتراك بالبرنامج -ديوانية LGG : هذا البودكاست نتكلم فيه عن ما كنا نلعبه في الاسابيع الماضية. حيث يقوم
في هذه الحلقة Valiant Hearts: The great war Shovel Knight Muramasa و المزيد ! قام بتسجيل هذه الحلقة : يعقوب الحسيني، حمد الحميدة، عبدالله بوشهري و عادل بارودي من نحن طريقة الإشتراك بالبرنامج -ديوانية LGG : هذا البودكاست نتكلم فيه عن ما كنا نلعبه في الاسابيع الماضية. حيث يقوم طاقم الفريق بتقديم وجهات نظرهم وآرائهم وتبادل الخبرات
Tom Du Croz presents #LondonGigGuide your weekly, no nonsense, no bullshit guide to London gigs on ZoneOneRadio Each week Tom brings you an hour of music from the best bands playing smaller venues in the next week and gives you all the gig details details you need. This week ethical music promoter, musician and regular #LGG guest Ian Bennett pops in for a chat. And, of course, loads of great music from acts including Jake Isaac, Beatrix Players and Mock Deer. Tom plays every kind of music – it just has to be good. The result is a mix of indie, folk, funk, swing, ska, punk, pop and anything else that takes our fancy that week. You can find details of all the gigs mentioned and hear the tracks again by going to the website - http://www.londongigguide.co.uk. -- http://www.twitter.com/londongigguide and http://www.twitter.com/z1radio http://www.londongigguide.co.uk and http://www.ZoneOneRadio.com http://www.facebook.com/thelondongigguide and http://www.facebook.com/thelondongigguide
في هذه الحلقة The Legend of Zelda: A Link Between Worlds Tearaway Forza Motorsport 5 Spelunky Dead Rising 3 Killer Instinct Crimson Dragon Rogue Legacy Assassin’s Creed IV: Black Flag و المزيد بالاضافة إلى بعض الأخبار ! قام بتسجيل الحلقة كل من: يعقوب الحسيني، حمد الحميدة، عادل بارودي، و عبدالله بوشهري طريقة الإشتراك بالبرنامج -ديوانية LGG : هذا البودكاست نتكلم
في هذه الحلقة Xbox One The Legend of Zelda: A Link Between Worlds Knack Battlefield 4 Ryse: Son of Rome Broken Sword – the Serpent’s Curse و المزيد بالاضافة إلى بعض الأخبار ! قام بتسجيل الحلقة كل من: يعقوب الحسيني، حمد الحميدة، و عبدالله بوشهري طريقة الإشتراك بالبرنامج -ديوانية LGG : هذا البودكاست نتكلم فيه عن ما كنا نلعبه
في هذه الحلقة PlayStation 4 Killzone: Shadow Fall Resogun Knack Super Mario 3D World و المزيد بالاضافة إلى بعض الأخبار ! قام بتسجيل الحلقة كل من: يعقوب الحسيني، حمد الحميدة، علي الدهيش، عبدالله بوشهري و عادل بارودي طريقة الإشتراك بالبرنامج -ديوانية LGG : هذا البودكاست نتكلم فيه عن ما كنا نلعبه في الاسابيع الماضية. حيث يقوم طاقم الفريق بتقديم
في هذه الحلقة Total War: Rome II Sonic Lost World Ace Attorney Dual Destinies Dragon’s Dogma: Dark Arisen Beyond: Two Souls و المزيد بالاضافة إلى بعض الأخبار ! قام بتسجيل الحلقة كل من: يعقوب الحسيني، حمد الحميدة، علي الدهيش و ضيف الحلقة حمد طريقة الإشتراك بالبرنامج -ديوانية LGG : هذا البودكاست نتكلم فيه عن ما كنا نلعبه في الاسابيع
في هذه الحلقة نتكلم عن تاريخ شركة سيجا (SEGA) ونذكر بعض الألعاب التي احببناها من فريق LGG والمعلقين قام بتسجيل الحلقة كل من: يعقوب ، عبدالله , حمد , علي , حسين تابعوا آخر حلقتنا عن طريق الآيتونز نتمنى لكم استماعا ممتعا !البعد الآخر هو بودكاست نقاشي نتحدث فيه عن موضوع معين
Krüppel-like factor 8 (KLF8) has only recently been identified to be involved in tumor cell proliferation and invasion of several different tumor entities like renal cell carcinoma, hepatocellular carcinoma and breast cancer. In the present study, we show for the first time the expression of KLF8 in gliomas of different WHO grades and its functional impact on glioma cell proliferation. In order to get information about KLF8-mRNA regulation qPCR was performed and did not reveal any significant difference in samples (n = 10 each) of non-neoplastic brain (NNB), low-grade gliomas (LGG, WHO°II) and glioblastomas (GBM, WHO°IV). Immunohistochemistry of tissue samples (n = 7 LGG, 11 AA and 12 GBM) did not show any significant difference in the fraction of KLF8-immunopositive cells of all analyzed cells in LGG (87%), AA (80%) or GBM (89%). Tissue samples from cerebral breast cancer metastasis, meningiomas but also non-neoplastic brain demonstrated comparable relative cell counts as well. Moreover, there was no correlation between KLF8 expression and the expression pattern of the assumed proliferation marker Ki67, which showed high variability between different tumor grade (9% (LGG), 6% (AA) and 15% (GBM) of Ki67-immunopositive cells). Densitometric analysis of Western blotting revealed that the relative amount of KLF8-protein did also not differ between the highly aggressive and proliferative GBM (1.05) compared to LGG (0.93; p