Podcasts about M1

UTMB 期间霞慕尼录制。这次我们和 Mount to Coast（见山）一起聊聊硬核的超马话题——从巴克利马拉松之父 Lazarus Lake、他的纪录片《The Hillbilly Scientist》聊起，再来讲讲超马这个"没有赢家、只有完赛者"的社群到底是怎样的存在。本期简介一个看着像时尚品牌的跑鞋公司，为什么一头扎进了最苦、最土、最不商业的超马世界？这期节目从 UTMB 期间的一场纪录片首映说起——《The Hillbilly Scientist》的主角 Lazarus Lake（巴克利马拉松和后院超马的创造者）本人坐着回答了各种热心观众提问，南子还当面问了他一天抽几根烟。后半段聊得更开：美国和欧洲的超马文化差在哪、为什么欧洲的运动员很多并非我们想象中的全职跑者、Cocodona 的搜索量怎么超过了西部 100、见山Mount to Coast怎么给"跟成绩无关"的普通人项目掏钱，以及法国运动员在自家门口的坡道上连爬 48 小时、睡了 45 分钟破世界纪录时全村人陪着跑的画面等等。最后是一个关于 UTMB 选手 Baptiste Petitjean 的故事——恐惧到崩溃大哭的 20 分钟之后，他还是回到了终点。出场人物主播：南子、佳凝（跑者日历）嘉宾：刘淇（Mount to Coast 全球体育市场营销经理）嘉宾：李晟（Mount to Coast 欧洲市场负责人）时间轴00:21 开场：南子喜提全球限量款 M1，佳凝的"代购专员"人设01:21 品牌定位：海报像 SATISFY/Bandit 那挂的，赛道却是硬核超马02:03 首映夜：纪录片《The Hillbilly Scientist》，Laz 本人惊喜现身答疑03:43 名场面：见面先问"你一天抽几根烟"；《The Finisher》与巴克利首位女性完赛者 Jasmin Paris05:50 Laz 的底色：癌症 1% 幸存者，"往后的每一天都是 bonus"；拄着拐杖穿越美国07:50 与纪录片结缘：不是砸钱谈来的赞助，是扎根社区后自然长出来的合作10:58 超马文化地图：日本和港台玩得多、国内稀缺——耿鲁聪 50 天跑 3100 英里14:00 后院超马 101：每小时准点发枪跑 6.7 公里，没有冠军，只有 finisher16:50 商业 vs 非商业：巴克利拒绝商业化，MTC 怎么跟它做朋友22:42 顶流下场：Mathieu Blanchard 跑巴克利、Courtney 转战 Cocodona 25024:17 美欧超马文化差异；欧洲年轻人流行"横穿一个国家"27:20 CCC 补给点偶遇：给 UTMB 拍片的 camera runner 竟是穿越法国纪录保持者31:02 美国打法：运动员团队 + Project Transcend，支持普通人的超越项目36:04 欧洲打法：运动员少而精（27 位），首年就 MCC 女冠、TDS 男冠、PTL 第二38:05 签人标准：先穿鞋、再聊价值观；"八百流沙小孩哥"Cody 从大使到运动员41:52 全职？不存在的：消防员、中学教师，还有银行 CTO"遛个弯"拿 PTL 第二45:21 超马正在变大：Cocodona 搜索量超西部 100；最后完赛的 Golden Hour 选手最受尊重48:37 服务不分品牌：西部 100 收摊后只剩 MTC 的帐篷；和 WISE、Compressport、韶音互相印 LOGO55:22 48 小时连续爬升世界纪录：全程只睡 45 分钟，街坊邻居全村陪跑1:04:43 Baptiste Petitjean 的 UTMB：恐慌模式里崩溃大哭，然后自己走回了终点

How can you teach yourself anything, even when it challenges the way you see the world? And how can you organise what you learn so it turns into books your readers will find? J. Daniel Sawyer shares his self-education toolkit after decades as a largely self-taught author. In the intro, Spotify for Authors has expanded AI-assisted creation of audiobooks [Spotify]; Who is Narrating the Future? [Publishing Perspectives; 9 ways AI will disrupt authors and publishing from 2019]; Author Voice, Creativity, and Building a Career as an Intuitive Author-Entrepreneur [How Women Write]; A fallow season [Systems and Soul]; How to Write, Publish, and Market Short Stories – Joanna Penn. Today's show is sponsored by Bookfunnel, the essential tool for your author business. Whether it's delivering your reader magnet, sending out advanced copies of your book, handing out ebooks at a conference, or fulfilling your digital sales to readers, BookFunnel does it all. Check it out at bookfunnel.com/thecreativepenn This show is also supported by my Patrons. Join my Community at Patreon.com/thecreativepenn J. Daniel Sawyer is the author of over 30 books across science fiction, fantasy, crime, short stories, and nonfiction, as well as being a podcaster and filmmaker. His latest book is Reclaiming Your Mind: An Autodidact's Bible. You can listen above or on your favorite podcast app or read the notes and links below. Here are the highlights and the full transcript is below. Show Notes What is an autodidact, and why school doesn't teach you how to learn How to triage information in a world of way too much How to recognise fear in your body and turn it into excitement for learning Sandboxing dangerous ideas so you can learn without threatening your worldview How to organise research and check quotes when writing nonfiction Why you should never publish a book dead You can find Dan at JDSawyer.net, and The Autodidact's Bible is out now on Kickstarter. Transcript of the interview with J. Daniel Sawyer Jo: J. Daniel Sawyer is the author of over 30 books across science fiction, fantasy, crime, short stories, and nonfiction, as well as being a podcaster and filmmaker. His latest book is Reclaiming Your Mind: An Autodidact's Bible. So welcome back to the show, Dan. Dan: Hello, Joanna. It's great to be back. Jo: Yes, indeed. You were only on the show a few months ago, which is rare I have somebody twice in the same year, so that is quite exciting. We talked about voice mastery last time, very different to the topic of today. But because we did talk a bit more about your background last time, we're going to jump straight into the book. So what is an autodidact, and why write a book on it? Dan: Well, an autodidact is someone who teaches themselves things rather than taking a course. It's not incompatible with being taught by others, of course, but there's a set of skills for being able to pick up new information, new disciplines, new hobbies, whatnot, that's really useful to have. I wrote the book because I was mentoring a friend's kid through high school. They weren't teaching her anything, and she was having a hell of a time figuring out how to get an education in a school that was just not interested in providing one. The process of the conversations over the course of a year forced me to surface all of the tools that I had developed, starting as a child, that allow me to pick up all of those disciplines you were talking about before, plus blacksmithing and academics and other stuff like that. While I have had access to a lot of amazing teachers in my life, I'm largely self-taught, and have become the world expert on a couple of topics as a result. I realised that the tools that you need to teach yourself and the tools that you get in school no longer overlap very much, at least in the US. The old style of classical education, and then the middling style of early school education, both gave you those tools so that when you left school, you were able to continue through the world growing. Nobody does that anymore, so I realised I needed to write a book about all this stuff while it was fresh in my mind, so I did. Jo: I love that. I don't know if it always was like that for some people, too. We all know now more about neurodivergence. Back in the day, when you and I went to school, that wasn't really talked about. It was like if you couldn't learn stuff in the way that it was thrust at you, then you were just dumb, maybe. Dan: Well, what you and I got in school was the very late end of the German model. The German model of education is what arose in the industrial era, and its job is to create good, obedient workers, not necessarily to create independent citizens who can think for themselves and who can move through a world that's changing and learn things. That kind of education came from an older tradition, but it wasn't well suited to pulling people out of the hinterlands and putting them in the factories in a way that they could understand what they were supposed to be doing. So the Germans developed a regimented system that was built around memorisation exclusively, rather than processing. Memorisation and repetition. Whereas a more classical approach would have you do memorisation as part of repetition, processing, evaluation, and creativity. So when you go to school, you get some of the toolkit you need, but not all of it. Jo: Yes, and then I think some people were just so bashed over the head with stuff that they didn't enjoy the process of learning, and maybe just moved away from it now. I want to come back on something you said there, that it didn't enable the independence, the thinking for yourself. We're living in this really weird time now where we're almost in a splintered world where you can find information on anything you want, but a lot of people are finding information, say, on TikTok or in AI-generated books with no rigorous fact-checking. So how can you think for yourself in a world where there's almost way too much now? Dan: Well, one of the most foundational skills of thinking is information triage. The world has always been full of unreliable information, if for no other reason than the state of the art in any given field at any given time is guaranteed to be about 80% wrong. So even if you're being very careful about only hewing to the most accepted body of facts, facts change over time, partly as we learn more and partly as the world changes underneath us. Thinking is different than knowing. Thinking is the ability to evaluate the information you're coming into contact with and figure out what's likely to be useful, and then to check yourself based on what you are more inclined to believe because of the way that you're made up emotionally. It's being able to curb your impulses with an error-checking layer so that you don't get sucked down into a very nasty rabbit hole, which everybody's prone to on one front or another. So that explains the how and why, but the what is things like knowing your basic logic, knowing the informal logical fallacies that everybody's prone to, things like the bandwagon fallacy. We're partly herd animals. We tend to want to join a group for protection and identity. So if we're in a group that believes a certain thing, we're likely to believe it out of fashion, which is great for group solidarity. It's not so great for actually knowing if what you think you know is correct. I've got a whole section of the book devoted to the top 30 or 40 most common informal reasoning fallacies. Knowing how to do basic critical reasoning is one of the things you have to do if you're going to be learning in a way that's useful to you. Then of course, there's another reasoning kit, which is the non-rational reasoning kit, which I also talk about. That's something that you and I as fiction authors use all the time. Jo: Explain more about that [non-rational reasoning kit] then, because people might not know what that is. Dan: All right. So rational reasoning involves logic. If X is true and Y is true, then Z must also be true. That's basic deduction. It basically lets you figure out what's implicit in the body of knowledge you already know. Then subsidiary to that is induction, which is, if X is true and Y is true, what might also be true that could explain X and Y? That's the scientific method. It's less reliable than deduction, but it actually grows your knowledge rather than just revealing it. Non-rational reasoning is things like reasoning through analogy, reasoning through metaphor, reasoning through intuition. These are all reasoning modes that allow you to bring something foreign into your understanding, or to deepen your understanding of something you're already familiar with, in a way that incorporates not just logical propositions, but also emotional truth and relational truth and things like that. Frequently it can generate things you can then subject to logical evaluation and pull new information about the world out of. A really good example of where this happens in science is in visionary experiences. The periodic table, for example, came out of someone's dream. Now, the fact he dreamed it doesn't mean it's true, but what happened while he was dreaming is he had a non-rational reasoning chain that brought him this vision, which he then brought out into the real world and started doing experiments on to see if it would work, and it did. Jo: In that case, yes, I can picture the periodic table, and I often see images of things that help me organise information. So that to me makes sense in terms of somebody who had certain amounts of knowledge, who had some kind of picture in their brain and then was able to prove that. I wanted to circle back. You were talking about critical things, rational things. You mentioned logic, and you did briefly mention emotion and intuition. Coming back to where we are at this point in history, so much emotion is being triggered through the media, whether that's social media or traditional media or whatever, that all of those logical, reasoned things can be almost triaged immediately by a big emotional response to something. So how can we understand that that emotional response perhaps has to be part of the triage? Dan: Well, simply by stating it outright. What you just said is exactly correct. I've got a model in the book where I talk about the difference between feelings and emotions. Feelings, in this model, are your interpretive layer. That's, I feel angry or sad or excited or depressed or whatnot. Those are your feelings. The emotions are the base physiological states that those feelings are laying over. So elevated heart rate, increased skin conductance, things like that are associated with any excitable state, like anger, sexual arousal, anticipation, fear, that kind of thing. Then depressed heart rate and whatnot, those are associated with depression, relaxation, and a whole bunch of other things. Learning to recognise the base physiological layer within yourself that's being stimulated allows you a certain amount of freedom about interpreting that base physiological state. That can help you separate your reaction to your own physiological state from your rational evaluation of what's going on around you. One of the things that our world runs on right now is fear, and there's reasons for this. If you read Edward Bernays' Propaganda, he lays it all out. Fear shifts your mind into a survival mode. You're less likely to take time to think through things. You're more likely to be easily steered because, as far as your physiology knows, there's an active threat to you, and you've got to take care of that. You've got to get away from it. If you stimulate fear in somebody, you can direct who they hate, who they love, who they trust. Very, very useful for anyone who wants to build a cult or sell a product or get elected. If you learn to recognise in yourself that the physiological state associated with fear is the same one associated with excitement over something new, then you can train yourself, to a certain extent, and it's a learned skill, to do an end run around the fear part and concentrate on the excitement. Then you can deal with whatever it is that's stimulating you in the way that you would a new piece of information, a new bit of learning, a new adventure. Instead of fear, which closes you down, adventure opens you up, and that's a much better state to engage in learning and exploration than fear is. Jo: When you said, “That opens you up,” this is exactly what I look for, what is expansive for me. I often reflect on this. When do I feel expansive, and when do I feel like I'm being reduced? When do I feel like I'm hunkered down? When I'm working with AI tools, I feel expansive, I feel more creative, I feel excited. I feel all these things where I just see so many possibilities, and the horizon is off out there in the distance. Yet I know other people, some people listening, will feel that that crushes them, that even mentioning it just makes them reduce into themselves and shrink because of fear, I guess. I also think that a lot of people are feeling those things because they haven't learnt enough perhaps. They are just responding to emotions. So how can we change those things so we're more open to learning? Dan: Well, one of the things you run into with creative types is we've all got something weird in our background that makes us do this. We're not just inclined to be creative, because you can meet welders and electricians who are very creative people. They just apply their creativity in a limited domain. People who go into the arts tend to be either people who grew up in incredibly open conditions, or people who grew up in incredibly closed conditions and had to fight against them. People who grow up in closed conditions and fight against them tend to be a little better at sticking around for the long haul of an arts career, which can be punishing financially and emotionally. One of the reasons they can stick around is that they had a lot of practice in sticking around through horrible situations when they were younger. So they're going to have a negative bias when they come up against things that they don't understand. If you have a negative bias with something you don't understand and it turns out to be wrong, you're not going to lose very much. But if you have a negative bias when you come up against something you understand and it turns out to be right, you're going to survive that thing. Whereas a more open person might just walk into the jaws of the shark, right? To change that and make your experience better, and give you access to all the advantages that the person who's got a more open temperament has, you've got to find a way to make it safe to experiment with the dangerous thing. For every dangerous thing, and probably for everyone who's encountering it, it's going to be a little bit different. With AI, people are worried about the market eroding to the point where nobody cares about human creativity anymore. In fact, my first publishable short story, which is called We Create Worlds, was actually about a novelist trying to outwrite the AI novels. It's become weird. Jo: What year did you write that in? Dan: That was in 1999. Jo: Awesome. Dan: It's still a great short story. I did do it in podcast form, which you can find on my website at jdsawyer.net, and it's also in ebook on Amazon, and it's part of the Sculpting God short story collection. But the fear is that humanity gets crowded out of the market in the face of the relentless onslaught of the machines. It's not a ridiculous fear, especially if you look at the history of artisanship. Everybody and their brother used to have an artisanal business, and now we've got machines that weave socks and make just about everything in our world. So people like me, who spend half my day every day in a blacksmith's forge making hooks that you could just make by machines way cheaper, are kinda crazy. But there's a market for that. Humans like things that were touched by other humans, as long as they can afford them or justify making a luxury. On the other hand, the people that adopt tools early and figure out how to make them work for them, those are usually the people that win at scale over the long haul. So, AI is coming for our jobs, guys, but you know what? You can keep it out of your creativity and build agents that help you deal with your scheduling and your bookkeeping and your marketing, all the other stuff that takes up your time as an author. Then instead of threatening your creativity, it gives you more space to be creative. Jo: So it's reframing things a lot of the time. Dan: A lot of the time, yes. Jo: I think that's true of everything. Reframing can help you learn. Reframing things can give you a reason to learn, I guess, when in the past, maybe at school, you hated learning… Dan: Yes. Jo: Now by reframing it into a reason why. Dan: That really helps, and it also helps the second big problem with learning, which is worldview threat. I think I open the book with an entire section on how worldviews work and how that limits us, and how we can't get away from them even though they limit us. Your worldview is the matrix through which you experience everything around you, and it's not a window, it's like a lens. It distorts everything, it filters everything, because it's the reflexive layer that helps you make sense of the world, and it's built out of your experience and inflected by your personality and other things like that. There are things you can learn, and for everyone it's going to be a little bit different, that threaten everything about your worldview. That's a problem, because your mind experiences your worldview not as an interpretive matrix, but as a survival tool. As far as your deep mind goes, your worldview is perfectly okay because you're still alive. Its job is to keep you alive. So if you learn something, or come close to learning something or thinking something that could unspool a big part of your worldview, you'll just emotionally go blank. You'll shut down. The information you're encountering will not register, or it will make you angry and you'll steer away from it. This isn't very good if you're wanting to learn things or grow. So there's a set of metacognitive tools you can use to help you push past that and navigate the existential crises that can sometimes ensue without crushing you entirely. I spend a section of the book talking about that as well, and detailing what some of those tools are. Jo: Better give us a tool. Give us one useful tool. Dan: All right, so one of the basic tools is one that anyone who's a developer in the audience will be familiar with, and it's basically sandboxing. You create a little playpen where it's okay to play with this dangerous idea, and you make yourself the promise that until you're really familiar with the dangerous idea, you're not going to connect it to anything else in your worldview. Then you've got the option later on to decide whether to integrate it or not. But you've got to play with this scary tool. For someone who comes out of a fundamentalist religious background like I do, one of the big ones here was textual criticism, where you learn about all the manuscript traditions that make up the New Testament especially, and the development of Christian scripture. I had to know about this stuff because I had a paid writing gig that required me to know about it. But I was a biblical literalist and believed that it all came straight out of God's mouth, and I couldn't even go near it without going, “Ah,” because intuitively some part of me recognised this could be a threat to what you believe. So I made myself a sandbox. I said, “This is a literary project. If I actually believe in the doctrines of my religion, then this can't be a threat, because even if the words themselves were changed all over the place, the Holy Spirit would have ensured that the important parts of the theology got through unscathed.” So I had a sandbox. I didn't really have to think about it. I could just learn the topic, and I got through. It was a two-year project, I had a fabulous time, and I came out knowing more about textual criticism than anyone ever should need to. I actually got to know someone, a friend of my father's, who actually makes the Greek New Testament from the surviving original sources. I learned all sorts of things about biblical translation and about classical literature. It was great stuff. I sandboxed it until I understood it, and then I decided whether or not to integrate it, and I did integrate it. It didn't actually have anything to do with me ending up being an atheist now. That was because of my research into mythopoetics several years later. When you sandbox something like that, you give yourself an imaginary play space. This is something you do any time that you go to a movie and you cheer for characters who are doing horrible things that you would never do or condone in real life. It's a fantasy play space that allows you to explore other aspects of life that you can't touch in real life. When you're learning, you can use that same set of skills of fantasy play and fantasy role play for trying out and exploring topics that might threaten the way you see the world. Jo: Well, that actually brings up a good reason to do this, and one of the reasons I love to learn new things is to turn them into books. You mentioned earlier your short story about AI, for example. That's a great way of sandboxing and playing with a dangerous idea. I'm actually writing a lot of, I guess we would call them science fiction, in the science fiction genre. I've never written science fiction before, and suddenly… Dan: Welcome to the party. Jo: Yes, exactly. I'm now writing science fiction. I haven't published any of it yet, but it's possible that I'm moving into science fiction because I am weighing up a whole load of these things as I'm learning about it, and I'm like, “Okay, how would I play with that idea?” So that is one way to use what we learn, or even, like we said, reframing it. One good reason to drive the learning in the first place, I guess. But in that way, I wanted to ask you, because your books are very detailed. How are you structuring knowledge as you learn it, in a way that is useful for turning it into something else later? Dan: Okay. Associatively. The way that the brain stores knowledge, it looks a bit like a spiderweb, or like a map of galaxies in the universe. That's probably too geeky. Let's stick with a spiderweb. Everyone's seen a spiderweb. You don't record discrete tabulated facts like a spreadsheet or a database. You actually record associative memories, and everything you know is associated not just with other things that fact might be associated with in a library catalogue. It's associated with the smell that you were smelling when you learned that thing, and the emotional state you were in when you learned that thing. The more associative connections you can make to any bit of knowledge, the easier it is to record. When I sat down and wrote The Autodidact's Bible, I literally wrote it front to back without an outline. There have been some books I've done this with where I had to rearrange afterwards. With this one, I didn't have to, because this is one of the places I live, so I've just got a good structure for the information in my head. I knew that if I wanted to convey this toolkit and all the things associated with it, I needed to start with what is knowledge and memory, and how does understanding work? Then move into worldview and the way that emotions affect the way that we learn, and developmental psychology, which has to do with the way the human being is designed to learn from the get-go. We start off with raw input. I call this in the book type zero learning. We get a fire hose of information we don't know how to make sense of, and our brain adapts itself to the inputs. Then there's type one learning, where we play around with things and we experiment and we see what they do. It's the “what's this button do?” approach to learning. Then there's type two learning, which is someone else who knows something already tells us things or shows us things, and we pick that up. All three of these systems are involved at every stage of the learning process. Actually, it's hierarchical. So you can do type zero learning without doing type one or type two. If you're doing type two, which is what you're doing in school, or when you're learning from a mentor, or when you're listening to a podcast, then if the information is going to stick, you are also involved in type zero learning, which is just taking in a bunch of stuff, and type one learning, which is practising and doing trial and error. Even if, as you're listening to this podcast, you're just reacting with things like, “Oh, now that's an interesting idea,” and you're having a little fantasy about, “What if I did this?”, that's a version of experiment and repeat, and that solidifies the learning in your knowledge web in your head. Then the trick is figuring out how to go back and find those things. Jo: Well, this is what I wanted to talk about. In the book, you do have stuff on memory and that kind of thing. I have definitely found, and this has got worse with menopause, and this is a completely normal thing with menopause for women, the brain fog that means things don't seem to stick so well, and then the recall is also almost harder. I'm often reaching for things, and I can't get them back. I've always been somebody who writes everything down anyway, but I now do it even more. As you know, I sent written questions for this. I now rely on written stuff so much more. So when I'm writing a book, or like I've just been doing with this master's and a lot of research, I have to write everything down. So I guess my question was more about, for people listening who want to learn things in order to write books from that— What recommendations do you have for organising your research so that when you write the book, you can reference it in a good way? Dan: Well, writing things down is great, because that is part of the repetition that helps it stick in your head, and then you've got an external place where, as long as you can remember where you put it, you know where to get it. The more connections you can make to any piece of information, the easier it is to find. I do take notes, and I have a strictly hierarchical file tree where I know where to find manuscripts and files full of notes and whatnot. What often happens with me is I will make notes on something, and then I'll forget I did it, and then a few years later I'll write the book and then discover the notes again afterwards, and the book basically matches the notes. I think the reason that happens is that when I get an idea in my head and write it down, I just start subconsciously playing with the idea, and I play with it and play with it until it's well developed. Every time you take an idea out, or a memory, and play with it, everything that you're thinking or feeling at that point in time gets reconnected to it. So you actually alter a bit of what you're remembering, but you're also multiplying the mental paths you can use to get to it. So you've got a very strict external system to help you beat the brain fog. The analogy to do it without the external system is you create that kind of system in your head. You practise actually walking the system like it's a library or a museum. If you're a very visual person, and this doesn't work if you have aphantasia, you can close your eyes and you can walk through the museum in your head, and you can turn to the left and see a room that's associated with everything you know about biology, and then you can start picking things up in that room. I'm actually being semi-literal here. I sometimes actually do this like I'm working in virtual reality. Most of the time it's not that concrete, but if I'm trying to find something and I get stuck, I will actually close my eyes and go into the museum and find the room. The other trick is you don't chase a particular bit of information too hard. All you're looking for is something that's in the neighbourhood. Because once you start working mentally in the neighbourhood, all of that knowledge map comes back to you as a side effect of being in that area. Let's say you're in England, and you knew neighbourhoods in Nottingham really well, and you wanted to go visit a friend in Nottingham. When you get on the road to go, and you're not using a map, you don't have the whole map loaded into your head. All you know is, I'm going to go that way on this road, and then you see the exit off the M1, or whatever it is, that you recognise. “Oh, this is the exit I take,” so you take that exit. All the other information in between, you kinda know it, but you drop it. You don't really actively search for it. Then when you get into the general area of your friend's house, you start to recognise landmarks and you go there. Memory of non-physical spaces works the same way, and you can actually develop the ability to engage it as if it's a physical space. The technique is called the mind palace. It was discovered in Ancient Greece, and it still works. Jo: Yes, and I agree with that, and I still have that kind of experience in a way. When we're writing nonfiction, and you have selected footnotes in this book, for example, although not to the extent of academic text, which is what I've been doing with my master's dissertation this week. As an example, I knew that Stephen King had said something like, “Writing is a form of telepathy,” but could I remember where it was? No. hTen I was like, okay, well, it's very likely it's in either one of his introductions or it's in On Writing, his memoir of the craft, because that is an iconic book. But in order to actually get the right quote, because if you're quoting people, obviously it has to be an exact quote as opposed to a made-up thought. Then if you're doing a proper footnote, for example, it does need what book it is and what edition and what page number and all of that kind of thing. So when you're writing the nonfiction books, are you doing the memory palace thing, writing the stuff, and then going back and finding where you got it from? Dan: Yes, and anything that's vague, I just put hard brackets around it. I don't remember all the people I quoted, but let's say I quoted Schopenhauer. If I was going to be quoting Schopenhauer and I could remember what he said, but I couldn't remember the words, I'd just put brackets around it and say, “Find the place where Schopenhauer said this,” and then put the quote here. I don't use hard brackets anywhere else in my writing, so I can then just Control + F, find the hard bracket, and retroactively do the research. Jo: Yes, exactly. I think that is the point I was trying to get to, which is it's all very well having the memory palace, but I can bet you that some of these quotes are not correct. Dan: Yes, always check quotes. Now with AI, there's search engine techniques where you can actually start from a paraphrase and then refine the search stepwise until you can get the exact quote with a reference, and then you can check it against the manuscript online. I use a lot of those when I don't have the book that I'm thinking of in my hands. Now of course with AI, I'm like, “Where did this author say this thing…” Jo: Roughly? Dan: Yes, roughly. The AI will come back with, “Well, he said this in these words in that book, and these words in that book.” And I'm like, “Oh, boy, I get to pick which one works better for what I'm writing.” Jo: It's very good. Coming back to what you were writing, I think you have balanced footnotes and source material, but you haven't gone as far as the academic footnoting of every single sentence, which is where I am at the moment. So for general nonfiction that is trying to reach a broader audience, where would you say the balance lies? Because I just feel now that we don't do enough of this in the indie community. I read a lot of nonfiction books which need a heck of a lot more attributions. Dan: First of all, I subscribe to the Terry Pratchett school of footnotes, which is that footnotes are places for long asides that need to be there, but that interrupt the flow of the text. I'm sure you noticed. Also, for me, it's really important, wherever I can remember where I got an idea, to point it out so that the reader can follow that rabbit trail if they want to. As a nonfiction writer, I feel like I'm in the business of providing value to the curious person. So anywhere I can point them where they might have fun exploring further is a value add. That's something I try to do, but I don't always remember, because in the heat of composition, you don't really realise where the ideas are coming from all the time. The second thing is, if I'm directly quoting or paraphrasing someone, there's always at least an attribution to the author, if not in the footnotes, then in the body text. You know, as Harlan Ellison used to say about being paid as a writer, or whatever. The great glory, and this is at least partly an aesthetic thing in my head, the great glory of nonfiction is that it taps you into an entire universe of conversations that have been going on as long as there's been a written word. To pretend that you're not participating in that conversation, okay, it might make you look cool to the novice reader, but you're really depriving your reader of even just the bare awareness that he's dipping his toe in a rich stream that he could follow forever. Especially in our world where we live in a TikTok world, but before that, we lived in a soundbite world, and before that, we lived in the newspaper world. These are all formats that try to pretend that they exist outside of time and culture, even though they're the most temporally dependent and culturally fickle sorts of entertainment there are. We've gotten used to the experience of encountering something that feels like it could just be from anywhere, and that's not the way it really works. Every TikTok video comes out of someone's experience, which is embedded in a culture, which is embedded in a tradition that's full of controversies that goes back to the beginning. It's not just full of controversies, but it's accompanied by stories, fictional stories, mythic stories, where those controversies get fought out and explored. I think as a nonfiction author, if you want to be really selfish about it, it makes you look better if you're also pointing at the tradition that you're standing in than if you're pretending that it's all coming from you. Jo: Yes. It makes you look better if you are citing things. I feel like that's such a good reframe. I was reading a book the other day, and I was like, all these ideas are coming from all these other people that I know about. This person would look a lot better if they actually accredited those ideas to the people they came from. My opinion of that person went down because they were not attributing. So, yes, I think it's so important, and that's the fun bit. Let's circle back to the fun bit of learning. Dan: Before you get onto that, I should point out that in my writing, I don't do this with academic rigour. I do it as it occurs to me. I write a weekly nonfiction article dealing with philosophy and history and arts and everything, and I don't always think, “Oh, the readers might not know where this comes from,” and stick it in there. But over the course of reading those articles, you get all the citations. They're just not always in every article. Jo: Oh, no, I've read your stuff, Dan. You do a good job. Obviously not to the academic attribution detail, but I do think this book in particular, Reclaiming Your Mind: An Autodidact's Bible, has a lot of references so people can learn more. So I do briefly, before we finish, because you and I could talk about this forever, but I do want to ask about Kickstarter. So you're using Kickstarter to launch this book. You've done a couple of campaigns, but not for a while. So why use Kickstarter for this, and what are the pros and cons? Dan: Well, as far as I've been able to work out, doing a Kickstarter is the one way you can make sure that you don't publish a book dead. Are you familiar with this term from old publishing? Jo: You can expand on it. Dan: Okay. So in traditional publishing, there's a term called publishing dead, which is where the publishing house buys a book, they go to the trouble of laying it out and printing it, and then they just kinda drop it on the market with an entry in the bookseller's catalogue. There's no publicity, no fanfare, no attempt to get advance buzz going, and it just kinda sits there. Occasionally someone who buys for a bookstore will get a couple of copies, and they'll sit on the shelves, and a customer will walk by and buy one. Books that are published dead tend to sell 500 copies over a 30-year lifetime. It's not much. Jo: That's probably a lot of indie books as well. Dan: That's how most indie books are done. The first 10 years of my career, I was doing fiction podcasting, so everything I was publishing got published live, and they did really well. Then fiction podcasting kinda died at the same time that my life got really complicated, and so I decided just to let my podcast die with the wave. At just the same time, my personal fiction productivity went through the roof. I went from writing one, maybe two books a year to writing four or five. I was dropping these four or five books on the world and nothing happened, and all the sales were drying up anyway from the older stuff that had been supported by the podcast. So I decided I wanted to find a way to stop publishing things dead. I had done a Kickstarter for an audiobook years ago that I produced for Gail Carriger, and so when I was writing Secrets of the Heinlein Juvenile, I decided there's a lot of Heinlein fans out there, so even if I don't personally have the name recognition, this is something that I could launch pretty well on Kickstarter. It did great, and I decided at that point that I was never going to publish another book dead. I was always going to have some kind of occasion to launch with, even if I had to manufacture it. In the years since, I've published very little, because I've been trying to figure out how to do that. I've got a big stack of books that are coming out now that I've figured it out. I realised that things like debuting in a book bundle, doing a Kickstarter, or finding a way to time a release with a news cycle, which is appropriate for some science fiction particularly, these are ways to publish a book without publishing it dead and then having to try to figure out why nobody's noticing it. So that's why I'm doing the Kickstarter. Jo: I also agree. What I like is doing the two-week campaign. I normally do two-week campaigns, because then I can just focus my energy before the campaign and then during those two weeks, and then I'm basically done, and then I put it up on all the platforms and everything. I focus most of my energy into that couple of weeks beforehand and then the two weeks of the campaign. Like you, I mean— We don't want to be spending all our time marketing, but to try and make it an occasion just helps us put a bit more effort into it, doesn't it? Dan: It really does. And the other thing it does, and this took me a while to figure out, but I've come to understand that most people's relationship with their favourite writers isn't like my relationship with my favourite writers. I've got about 70 writers I like, but I've got about 10 where I don't care what happens, I will buy and immediately read what they've done. I realised that for most people, their relationship with most of the writers they like is more at arm's distance. They stumble across, “Oh, I didn't know this guy had something new. I'll pick it up,” rather than being like, “I love the way this person's mind works, and I want to see what it goes at next.” So the bread and butter as an author has got to be in making sure that those people find you. It's not in serving the core base, the core 1,000 fans. They're really important, and you want to do that, but if you want the career to sustain and build, you've got to find ways to help people in that second group, the arm's-length fans, stumble over what you're doing. Because everybody's got more important things in life than your books. But if you've got excuses to be stumbled upon that don't involve standing right up and waving a sign saying, “Buy my book, buy my book,” then you're more likely to build momentum, because people talk about the book they just read and that they love. If they don't talk to someone in the first few days after they read that book, then unless it was one of the books that changes their life, they're never going to talk about it again. So you want to get as many people talking about the cool book they read last week at the same time as possible, to build momentum. Jo: Indeed. Right. So where can people find your cool book, as well as all your other books, online? Dan: Reclaiming Your Mind: An Autodidact's Bible is currently Kickstarting. You can find a link on the top post at my website at JDSawyer.net. You can find all my books at JDSawyer.net/book-list, and you can find my weekly articles on maker stuff, philosophy, creativity, and history at jdanielsawyer.substack.com. Jo: Brilliant. Well, thanks so much for your time, Dan. That was great. Dan: It was a pleasure, as always. The post Reclaiming Your Mind: How To Teach Yourself Anything With J. Daniel Sawyer first appeared on The Creative Penn.

Mitsunori Chiba's journey to the top of the bench press world began just six years ago, shortly after he arrived in Australia on a working holiday visa. This May, representing Australia at the IPF World Bench Press Championships in Poland, he won the M1 -83kg title and was named the competition's Overall Best Lifter. - 今年5月、ポーランドで開催されたIPF世界ベンチプレス選手権。オーストラリア代表として出場した日本人選手、千葉満徳さんが、M1 -83kg級で優勝し、大会最優秀選手賞にあたるOverall Best Lifter賞も受賞しました。世界の頂点に立った千葉さんですが、ベンチプレスを始めたのはワーキングホリデーでオーストラリアに来て間もない6年前でした。Listen to SBS Japanese Audio on Tue, Thu and Fri from 1pm on SBS 3. Replays from 10pm on Tue, Thu and Sat on SBS1. Listen to past stories from our podcast. Download the free SBS Audio App and don't forget to visit SBS Japanese Facebook and Instagram page! - SBSの日本語放送は火木金の午後１時からSBS3で生放送！火木土の夜10時からはおやすみ前にSBS1で再放送が聞けます。SBS日本語放送ポッドキャストから過去のストーリーを聞くこともできます。無料でダウンロードできるSBS Audio Appもどうぞ。SBS 日本語放送のFacebookもお忘れなく。

Neurologist David Perlmutter MD says the beta-amyloid theory of Alzheimer's is wrong — and the real culprit is your brain's own immune cells. In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with the #1 New York Times bestselling author to unpack his new book Brain Defenders: how diet, blood sugar, and metabolic health flip the brain's microglia from protective to destructive, why anti-amyloid drugs offer "trivial" benefit, and which biomarkers actually predict your brain's future.Chapters:00:00 — Introduction01:38 — Why He Left Mainstream Neurology to Prevent Brain Decline05:24 — Building the World's Largest Integrative Neurology Practice06:55 — The Common Pathway From Metabolism to Brain Degeneration08:25 — Why the Beta-Amyloid Theory of Alzheimer's Is Wrong09:11 — What Are Microglia? The Brain's Immune Cells (M1 vs M2)12:13 — From Brain "Glue" to Master Regulators of Your Synapses16:00 — How Body Inflammation and Cytokines Reach the Brain18:15 — Leaky Gut, the Microbiome, and Brain Degeneration19:46 — Ultra-Processed Foods Raise Alzheimer's Risk Up to 270%25:02 — Synaptic Pruning: The Link Between Autism, ADHD and Alzheimer's29:36 — Why Diabetics Recover Worse From Head Trauma31:51 — Anti-Amyloid Drugs: "Trivial" Benefit, Serious Harm35:37 — The Biomarkers to Track: Fasting Glucose, Insulin, A1C40:09 — On the Horizon: Mitochondrial Therapies and Microglial Transplants45:26 — Glyphosate, Air Pollution and 40Hz Light Therapy47:00 — Brain Defenders Releases August 18 — Final TakeawaysKey takeaways:Alzheimer's is increasingly understood as a "synaptopathy" — a disease of lost synapses driven by the brain's own immune cells (microglia), not simply beta-amyloid plaque.Microglia shift from supportive (M2) to destructive (M1) in response to metabolic signals: high blood sugar, insulin resistance, elevated blood pressure, excess body fat, and inflammation.A long-term cohort found each daily serving of ultra-processed food raised Alzheimer's risk ~13%, with 10+ servings/day linked to a 2.7-fold (270%) increase.A Cochrane review of anti-amyloid antibodies found "trivial" cognitive benefit alongside meaningful harm, including brain swelling and microbleeds (ARIA).The most actionable brain biomarkers are cheap and accessible: fasting glucose, fasting insulin, A1c, waist circumference, and a continuous glucose monitor — aim for optimal, not just "normal."Emerging frontiers target the mitochondria inside microglia — metformin, CoQ10, urolithin A, exercise, fasting, ketones, and 40Hz gamma light therapy.Studies & sources:Weinstein et al., J Prev Alzheimers Dis — ultra-processed food and Alzheimer's riskCochrane Review (2026) — anti-amyloid monoclonal antibodies for Alzheimer'sIaccarino, Tsai et al. (Tsai Lab, MIT) — 40Hz gamma light and microgliaDr. Lufkin's book "Lies I Taught in Medical School": https://robertlufkinmd.com/lies/⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every other Tuesday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/

We hold these Monthly Virtual Town Hall Meetings so that we can engage with our listeners locally, nationally and internationally and encourage them to join the Grass Roots Community Activist Movement. We also want to raise funds for our film project "Hood Liberator Made In Chicago: The War Against Willie Lynch Begins" This film project is my last attempt to try to do something positive for my racial group Black Americans who identify as (DAS-FM) Descendants of American Slaves/Freedmen. We host our Monthly Virtual Interactive Conference on the last Saturday of the month. We're trying to raise $250 thousand dollars so that we can make a quality Black Empowerment Film based on my experience growing up in the inner cities of Chicago and having to endure all kinds of push back from Black Chicago for trying to get my Black Christian business up and running in the Black Community. I want to encourage seasoned Black American Film Makers and African Film Makers from across the United States of America to consider working with us in getting this film fully funded and made because it is needed now more then ever. #NotAnother34Years, #M1, #DAS-FM, #JoinGRCAM

We hold these Monthly Virtual Town Hall Meetings so that we can engage with our listeners locally, nationally and internationally and encourage them to join the Grass Roots Community Activist Movement. We also want to raise funds for our film project "Hood Liberator Made In Chicago: The War Against Willie Lynch Begins" This film project is my last attempt to try to do something positive for my racial group Black Americans who identify as (DAS-FM) Descendants of American Slaves/Freedmen. We host our Monthly Virtual Interactive Conference on the last Saturday of the month. We're trying to raise $250 thousand dollars so that we can make a quality Black Empowerment Film based on my experience growing up in the inner cities of Chicago and having to endure all kinds of push back from Black Chicago for trying to get my Black Christian business up and running in the Black Community. I want to encourage seasoned Black American Film Makers and African Film Makers from across the United States of America to consider working with us in getting this film fully funded and made because it is needed now more then ever. #NotAnother34Years, #M1, #DAS-FM, #JoinGRCAM

AUA2026: Advanced Prostate Cancer in the News 2026: A Case-Based Multidisciplinary Update CME Available: https://cme.auanet.org/URL/26DC010ONL LEARNING OBJECTIVES: At the conclusion of this activity, participants will be able to: 1. Initial Management of Metastatic Prostate Cancer: Evaluate and treat a patient with new diagnosed M1 prostate cancer with androgen deprivation therapy (ADT) plus be skilled to offer novel oral androgen blockers/inhibitors. Furthermore, to recognize high volume new M1 prostate cancer so as to be able to partner with GU medical oncologist for docetaxel chemotherapy in a multidisciplinary team. In addition, to recognize and employ molecular genetic testing to help dictate proper therapy. 2. Non Metastatic Castrate Resistant Prostate Cancer (M0 CRPC): Diagnose M0CRPC and to be able to educate patients about using novel oral androgen receptor targeted agents added to traditional ADT as a way to improve their patent's overall and radiographic progression-free survival. Furthermore, the skilled learner will be able to understand the differences between these three novel oral agents and to educate patients about side-effects and toxicities. Finally, to understand the pros and cons of PSMA PET scan imaging in further staging in this disease state. 3. Metastatic Castrate Resistant Prostate Cancer (M1 CRPC): Define and have a working knowledge of the latest phase III RCT results for new therapies in M1 CRPC and to be able to educate their patients on treatment options and be able to participate in a multidisciplinary team caring for men with this disease state of far advanced prostate cancer. 4. Identify that advanced prostate cancer is a complex group of disease states with an ever changing therapeutic landscape and for providers and teams to embrace the multi-disciplinary nature of care for our patients. 5. Describe the molecular and molecular genetic underpinnings of advanced prostate cancer and recognize the future will be based on a more personalized therapy landscape including PARP inhibition, Immune Checkpoint agents and novel AR targeted agents emerging in 2026 and beyond. ACKNOWLEDGEMENTS: Support provided by independent educational grants from: Astellas Lantheus Medical Imaging Novartis Pharmaceuticals Corporation Pfizer, Inc

I start medical school TOMORROW—and after years of figuring out how to get into medical school, now I have to figure out how to actually study in it.

SSDs und Arbeitsspeicher sind weiter teuer, und wie die c't-Experten Christian Hirsch und Florian Müssig analysieren, wird das vorläufig so bleiben – und zwar nicht nur ein paar Wochen lang, sondern eher auf einige Jahre hinaus. Aber derart lange vorhandene PCs und Notebooks weiter zu nutzen und die Speicherkrise einfach auszusitzen, ist nicht für jeden praktikabel. Lässt sich ein Neukauf nicht weiter hinauszögern, sollten auch Gebrauchtgeräte in die Überlegungen einbezogen werden. In diesem Video-Podcast stellen wir Hardware-Empfehlungen zusammen und diskutieren Alternativen wie externe SSDs oder Aufrüsten. Auch warnen wir vor einigen Fallstricken, denn inzwischen ist auch der Gebrauchtmarkt ganz schön abgegrast. Die empfehlenswerten Gebrauchtgeräte sind Firmenrückläufer. Was nach drei Jahren abgeschrieben ist oder aus dem Leasing fällt, geht an Refurbisher, die sich um Details wie das Aufspielen gültiger Windows-Lizenzen kümmern. Aber weil auch die Firmen unter den gestiegenen Neupreisen leiden, nutzen viele die Geräte fünf Jahre und länger. Entsprechend ältere Geräte dominieren nun den Gebrauchtmarkt. In vieler Hinsicht ist das kein Risiko, weil wichtige Techniken wie schnelle Prozessoren, vollwertige USB-C-Ports und auch die Windows-11-Tauglichkeit seit vielen Jahren üblich sind. Aber Vorsicht ist dennoch geboten, da einige Händler nun auch die verstaubtesten Ladenhüter auf den Markt bringen. Und einige Details wie gute Mikrofone und Webcams kamen teils erst deutlich nach Corona in Mode und in die Firmengeräte. Christian und Florian geben weitere Tipps und erklären, warum auch die Gebrauchtpreise mit den Speicherpreisen steigen. Im Windows-Bereich sollte man Intel- oder AMD-Geräte kaufen. ARM/Qualcomm holt zwar auf, aber die guten Prozessoren sind im Gebrauchtmarkt noch nicht zu finden. Genau anders herum bei macOS: Für Intel geht die Unterstützung absehbar zurück, also sollte man gebrauchte Apple-Hardware nur mit M-Prozessoren kaufen – der M1 ist für vieles weiterhin schnell genug. Dem Aufrüsten – sowohl der eigenen Geräte als auch etwaigen nur zu schwachbrüstig gefundenen Gebrauchten – sind enge Grenzen gesetzt: Bei vielen Notebooks ist der Speicher fest aufgelötet, der Prozessor inzwischen immer. An die SSD-Module kommt man zwar bei manchen Modellen, aber fast alle Firmen-Notebooks vertragen nur ganz bestimmte Module. Die c't-Redakteure erklären, warum man dann nicht einmal herausfinden kann, welche Module das sind. Spannend in dieser Hinsicht sind die modularen und aufrüstfreudigen Notebooks vom Hersteller Framework. Diese durchaus erfolgreiche Firmenstrategie führt allerdings dazu, dass Framework im Gebrauchtmarkt kaum eine Rolle spielt. Die Zusammenhänge erläutert Florian. Besser sieht's bei Desktop-Rechnern aus. Passende RAM-Riegel und SSDs lassen sich einfacher finden, und mit etwas Vorplanung verträgt das Mainboard sogar noch ein paar neuere Prozessorgenerationen. Trotzdem empfehlen Christian und Florian, gebrauchte Notebooks und PCs komplett zu kaufen, vor allem aufgrund der Händlergewährleistung. Das ist auch der Hauptgrund, weswegen die c't-Redakteure vom Privatkauf abraten – oder man sollte sich zumindest der Risiken bewusst sein, auch in Bezug auf Verschmutzungen oder Windows-Lizenz. Zudem haben die Consumer-Baureihen inzwischen manchen technischen Fortschritt erst später bekommen als die Business-Baureihen. Ach, und wer Gaming-Grafik erwartet, der Podcast geht ausführlich drauf ein, aber die Kurzform ist: das gibt der Gebrauchtmarkt nicht her. Mit dabei: Christian Hirsch, Florian Müssig Moderation: Jörg Wirtgen Produktion: Tobias Reimer

SSDs und Arbeitsspeicher sind weiter teuer, und wie die c't-Experten Christian Hirsch und Florian Müssig analysieren, wird das vorläufig so bleiben – und zwar nicht nur ein paar Wochen lang, sondern eher auf einige Jahre hinaus. Aber derart lange vorhandene PCs und Notebooks weiter zu nutzen und die Speicherkrise einfach auszusitzen, ist nicht für jeden praktikabel. Lässt sich ein Neukauf nicht weiter hinauszögern, sollten auch Gebrauchtgeräte in die Überlegungen einbezogen werden. In diesem Video-Podcast stellen wir Hardware-Empfehlungen zusammen und diskutieren Alternativen wie externe SSDs oder Aufrüsten. Auch warnen wir vor einigen Fallstricken, denn inzwischen ist auch der Gebrauchtmarkt ganz schön abgegrast. Die empfehlenswerten Gebrauchtgeräte sind Firmenrückläufer. Was nach drei Jahren abgeschrieben ist oder aus dem Leasing fällt, geht an Refurbisher, die sich um Details wie das Aufspielen gültiger Windows-Lizenzen kümmern. Aber weil auch die Firmen unter den gestiegenen Neupreisen leiden, nutzen viele die Geräte fünf Jahre und länger. Entsprechend ältere Geräte dominieren nun den Gebrauchtmarkt. In vieler Hinsicht ist das kein Risiko, weil wichtige Techniken wie schnelle Prozessoren, vollwertige USB-C-Ports und auch die Windows-11-Tauglichkeit seit vielen Jahren üblich sind. Aber Vorsicht ist dennoch geboten, da einige Händler nun auch die verstaubtesten Ladenhüter auf den Markt bringen. Und einige Details wie gute Mikrofone und Webcams kamen teils erst deutlich nach Corona in Mode und in die Firmengeräte. Christian und Florian geben weitere Tipps und erklären, warum auch die Gebrauchtpreise mit den Speicherpreisen steigen. Im Windows-Bereich sollte man Intel- oder AMD-Geräte kaufen. ARM/Qualcomm holt zwar auf, aber die guten Prozessoren sind im Gebrauchtmarkt noch nicht zu finden. Genau anders herum bei macOS: Für Intel geht die Unterstützung absehbar zurück, also sollte man gebrauchte Apple-Hardware nur mit M-Prozessoren kaufen – der M1 ist für vieles weiterhin schnell genug. Dem Aufrüsten – sowohl der eigenen Geräte als auch etwaigen nur zu schwachbrüstig gefundenen Gebrauchten – sind enge Grenzen gesetzt: Bei vielen Notebooks ist der Speicher fest aufgelötet, der Prozessor inzwischen immer. An die SSD-Module kommt man zwar bei manchen Modellen, aber fast alle Firmen-Notebooks vertragen nur ganz bestimmte Module. Die c't-Redakteure erklären, warum man dann nicht einmal herausfinden kann, welche Module das sind. Spannend in dieser Hinsicht sind die modularen und aufrüstfreudigen Notebooks vom Hersteller Framework. Diese durchaus erfolgreiche Firmenstrategie führt allerdings dazu, dass Framework im Gebrauchtmarkt kaum eine Rolle spielt. Die Zusammenhänge erläutert Florian. Besser sieht's bei Desktop-Rechnern aus. Passende RAM-Riegel und SSDs lassen sich einfacher finden, und mit etwas Vorplanung verträgt das Mainboard sogar noch ein paar neuere Prozessorgenerationen. Trotzdem empfehlen Christian und Florian, gebrauchte Notebooks und PCs komplett zu kaufen, vor allem aufgrund der Händlergewährleistung. Das ist auch der Hauptgrund, weswegen die c't-Redakteure vom Privatkauf abraten – oder man sollte sich zumindest der Risiken bewusst sein, auch in Bezug auf Verschmutzungen oder Windows-Lizenz. Zudem haben die Consumer-Baureihen inzwischen manchen technischen Fortschritt erst später bekommen als die Business-Baureihen. Ach, und wer Gaming-Grafik erwartet, der Podcast geht ausführlich drauf ein, aber die Kurzform ist: das gibt der Gebrauchtmarkt nicht her.

SSDs und Arbeitsspeicher sind weiter teuer, und wie die c't-Experten Christian Hirsch und Florian Müssig analysieren, wird das vorläufig so bleiben – und zwar nicht nur ein paar Wochen lang, sondern eher auf einige Jahre hinaus. Aber derart lange vorhandene PCs und Notebooks weiter zu nutzen und die Speicherkrise einfach auszusitzen, ist nicht für jeden praktikabel. Lässt sich ein Neukauf nicht weiter hinauszögern, sollten auch Gebrauchtgeräte in die Überlegungen einbezogen werden. In diesem Video-Podcast stellen wir Hardware-Empfehlungen zusammen und diskutieren Alternativen wie externe SSDs oder Aufrüsten. Auch warnen wir vor einigen Fallstricken, denn inzwischen ist auch der Gebrauchtmarkt ganz schön abgegrast. Die empfehlenswerten Gebrauchtgeräte sind Firmenrückläufer. Was nach drei Jahren abgeschrieben ist oder aus dem Leasing fällt, geht an Refurbisher, die sich um Details wie das Aufspielen gültiger Windows-Lizenzen kümmern. Aber weil auch die Firmen unter den gestiegenen Neupreisen leiden, nutzen viele die Geräte fünf Jahre und länger. Entsprechend ältere Geräte dominieren nun den Gebrauchtmarkt. In vieler Hinsicht ist das kein Risiko, weil wichtige Techniken wie schnelle Prozessoren, vollwertige USB-C-Ports und auch die Windows-11-Tauglichkeit seit vielen Jahren üblich sind. Aber Vorsicht ist dennoch geboten, da einige Händler nun auch die verstaubtesten Ladenhüter auf den Markt bringen. Und einige Details wie gute Mikrofone und Webcams kamen teils erst deutlich nach Corona in Mode und in die Firmengeräte. Christian und Florian geben weitere Tipps und erklären, warum auch die Gebrauchtpreise mit den Speicherpreisen steigen. Im Windows-Bereich sollte man Intel- oder AMD-Geräte kaufen. ARM/Qualcomm holt zwar auf, aber die guten Prozessoren sind im Gebrauchtmarkt noch nicht zu finden. Genau anders herum bei macOS: Für Intel geht die Unterstützung absehbar zurück, also sollte man gebrauchte Apple-Hardware nur mit M-Prozessoren kaufen – der M1 ist für vieles weiterhin schnell genug. Dem Aufrüsten – sowohl der eigenen Geräte als auch etwaigen nur zu schwachbrüstig gefundenen Gebrauchten – sind enge Grenzen gesetzt: Bei vielen Notebooks ist der Speicher fest aufgelötet, der Prozessor inzwischen immer. An die SSD-Module kommt man zwar bei manchen Modellen, aber fast alle Firmen-Notebooks vertragen nur ganz bestimmte Module. Die c't-Redakteure erklären, warum man dann nicht einmal herausfinden kann, welche Module das sind. Spannend in dieser Hinsicht sind die modularen und aufrüstfreudigen Notebooks vom Hersteller Framework. Diese durchaus erfolgreiche Firmenstrategie führt allerdings dazu, dass Framework im Gebrauchtmarkt kaum eine Rolle spielt. Die Zusammenhänge erläutert Florian. Besser sieht's bei Desktop-Rechnern aus. Passende RAM-Riegel und SSDs lassen sich einfacher finden, und mit etwas Vorplanung verträgt das Mainboard sogar noch ein paar neuere Prozessorgenerationen. Trotzdem empfehlen Christian und Florian, gebrauchte Notebooks und PCs komplett zu kaufen, vor allem aufgrund der Händlergewährleistung. Das ist auch der Hauptgrund, weswegen die c't-Redakteure vom Privatkauf abraten – oder man sollte sich zumindest der Risiken bewusst sein, auch in Bezug auf Verschmutzungen oder Windows-Lizenz. Zudem haben die Consumer-Baureihen inzwischen manchen technischen Fortschritt erst später bekommen als die Business-Baureihen. Ach, und wer Gaming-Grafik erwartet, der Podcast geht ausführlich drauf ein, aber die Kurzform ist: das gibt der Gebrauchtmarkt nicht her. Mit dabei: Christian Hirsch, Florian Müssig Moderation: Jörg Wirtgen Produktion: Tobias Reimer

Azokkal együtt újul meg egyelőre az M1 híradója, akik korábban a propagandát gyártották Kamunak tűnő közbeszerzés: maradt az urambátyámrendszer augusztus 20-án Baka András első államfői döntése: hivatalvezetőt csinált Sulyok Tamás főigazgatójából A Fidesz is spórolással kezdte augusztus 20-át, de utána elszaladt velük a ló Az izraeli hadsereg elismerte, ők lőttek az ötéves palesztin kislányt szállító autóra Tényi István az Országgyűléshez fordult a közmédia-testület vitatott kiválasztása miatt Nem engedi be a Tisza a sajtót az augusztus 20-i országos találkozójára a Margitszigeti Nagyrétre Távozik az RTL Híradótól Zalavári Noémi Megszólalt Putyin az ukrán támadásokról és a gazdaság helyzetéről Magyarok Amerikában, itthon, a Parlamentben és az utcákon A csapatvezető kimondta: több kell Valter Attilától U20-as birkózó-vb: Szinay Szabolcs bronzérmes Zivatarfelhők árnyékolhatják be az ünnepi programokat A további adásainkat keresd a podcast.hirstart.hu oldalunkon. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Summer Blockbusters have a new champion as Spider-Man: Brand New Day resets the record books and for good reason. This movie is as fun a crowdpleaser as you're gonna find, and of course we loved it too. No Spoilers for the first half of the episode until we dive into the plot and the future of the MCU in the 2nd half. NON-SPOILER REVIEW OF SPIDER-MAN: BRAND NEW DAY: Highly rated reception numbers - 3:10 Biggest Box Office Preview Numbers Ever - 4:30 Why Gen Z should be running Hollywood - 7:27 Marvel better learn the right lessons from this - 9:16 Our Theatergoing experiences - 12:08 Destin Daniel Crettin's Bonafides & Our History w/ Holland - 13:30 Performance Reviews: How Tom & Zendaya are silencing critics - 17:34 The VFX Oscar Category Discussion + Oscar & Globes Talk - 24:58 SPOILER FILLED REVIEW: 34:00 The Big Moment & Best Characters - 34:50 Intrigue Going Forward - 40:03 Some Weaknesses & Nitpicks, but cathartic nonetheless - 47:37 Funny Little Moments Throughout - 56:10 Final Questions, Final Thoughts & Final Grades - 59:32 OUTRO: If you enjoy our podcast, please follow us on social media. M1 has been posting videos like crazy, and M2 just started going wild on Letterboxd. Plus, you can look forward to more Oscar Profile movie reviews in August as well as more Oscar Race Checkpoints, including Box Office Reactions to all of the records being broken by The Odyssey and Spider-Man: Brand New Day. https://linktr.ee/mikemikeandoscar

ぬるぽ放送局おたより投稿フォーム https://forms.gle/6tbmBzK6wbyavJG47 2026年7月パワープレイ M1. Comeback 作編曲：HiroHiro & Smeets 音楽ジャンル：Happy Hardcore, UK Hardcore サークル：Notebook Records 収録アルバム：YATSUZAKI HARDCORE COLLECTION 17 2026・7・1 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-017 番組時間：68分14秒 出演者：夕野ヨシミ、たくや VOICEVOX:ずんだもん VOICEVOX:四国めたん ---- 2026/7/30に公開録音したものを配信いたします。 ラジオ記事はリスナーのEEチャンピオンさんが書いてくれているので楽してます。 ＜オープニング＞ ・札幌寒いです ・台風くんはちょっと空気読んでほしいです ・落ち着いたらと思ってたら10年後に再びですよ ・イオシスくんの活動がんばったね報告 ・ブルアカの話します？ ・作詞提供しました！ 　『ブルーアーカイブ』 青春あんさんぶる Vol.19「特殊交易部」 　「特殊交易部はやめられない」 　アーティスト：ミヨ(CV:花岩香奈)／フユ(CV:十二稜子)／リツ(CV:　瀬戸桃子) 　作詞：夕野ヨシミ(IOSYS) 　作曲：KARUT 　『ブルーアーカイブ』 絆ダイアローグ Vol.26「キキョウ」 　「伝う距離、綾なす色」 　アーティスト：キキョウ(CV:小松未可子) 　作詞：john=hive(IOSYS) 　作曲：Nor 　『ブルーアーカイブ』 絆ダイアローグ Vol.27「カズサ」 　「I May…」 　アーティスト：カズサ(CV:夏吉ゆうこ) 　作詞：夕野ヨシミ(IOSYS) 　作曲：ミツキヨ ・「憧れの残響」も出てます ・始めるなら今！ ・2026/10/25 M3-2026秋 ブース当選しました！ありがとうございます！ 　■IOSYS S-06a 　なにか出ます！ 　※Notebook Recordsとの合同ブースです ・リミックス提供しました！ 　「ムリムリ進化論 (D.watt ムリなものはムリ Remix)／ナナヲアカリ」 　2026/8/26 CD Release ・タイトー『グルーヴコースター』シリーズ15周年のお祝いメッセージを掲載していただきました！ 　15周年すごい！おめでたい！ ・楽曲提供しました！2026/7/28から遊べます！ 　『ホロライブドリームス』 　「爆夏!!トロピカバケーション」 　歌：大空スバル/不知火フレア/白銀ノエル/角巻わため/音乃瀬奏 　作詞：かたほとり(IOSYS) 　作編曲：ARM(IOSYS) ・フルバージョンがYouTubeで見れます ・ホロドリ始めるなら今！ ・2026/8/21　IOSYSくま牧公開生放送　チケット販売中です　https://livepocket.jp/e/pnkrr ・2026/8/16　イオパあります ・2026/8/5からイオメンマルチプレイでNecesseやります ・TBAなので言えないことはいっぱいあります ・イオシスのファンになるなら今！ ＜Aパート＞ ・チルパフィーバーTシャツは在庫が少ないのでお早めに ・イオシスショップおチェックしてください ・つまぽん「来週は何もないですねー」 ・ふつおたです ・こんばんは、ちいかわです（嘘） ・東北の梅雨は中々明けない ・しょうゆを1滴1滴飲む仕事 ・そういう拷問があった気がする ・おすそ分け用の容器をたくさん買いました ・しょうゆvsみりんvsダークライ ・チケット販売中！よろしくお願いします ・ダークライも発酵調味料みたい ・ブルアカの話 ・詳しい人いたー！ ・ヤニねこが脳裏に… ・あれ？ブルアカに稲田さん出てる？ ・漫才一発やりますか ・下茹でと並行して本番行きますか ・爆笑問題さんの漫才をパクって出たいと思います ・せんのかい！ ・おショートですわ ・思っててえらい ・なぜか漫才もやるラジオです ・落語「おっぱい怖い」 ・おっぱいにおっぱいを重ねていこう ・今月の鉄アレイやってこう ＜Bパート＞ ・パワープレイ中に何回鉄アレイを上げ下げしましたか？ ・正解は不明です ・来月の曲を3回かけるか ・駅を降りたらスラム街♪ ・みつをたです ・イブキちゃんの水着がかわいい ・きるプラ ・夕野ヨシミ巡回済みじゃなかった ・映画館はどこに行けばいいの？ ・スガイディノス懐かしいですね　ｷｬﾊｯ ・にじさんじピックアップニュース ・ゴンさん状態の町田ちま ・なんでうまぴょい伝説でしめるの？ ・これ、完全に映画行こうの流れだよね ・モモカニ推し ・本屋さんを営んでるんですか？ ・ちら(かっていて)かわ(いそうな)夕野ヨシミ ・うち本棚埋もれてるけど来る？ ・ホロピックアップニュース ・食べないと冷蔵庫がヤバイ ・マリン船長 年齢ギリ耐え ・リアル凸待ち０ ・ぺこら「こ、こんなことが許されていていいのか」 ・ホロドリのストリームやるなら今！ ・Vピックアップニュース ・お風呂にポスター貼ってもいいですよ ・​​音ズレの訪れのコメント被り ・ホロドリは3Dのキャラがかわいい ・これ、やった方がいいですよ（小声） ＜エンディング＞ ・色々コンテンツを摂取してください ・水着を四捨五入したら全裸です ・帰ってホロドリやろう ・7月もおわりですよ ・8月はファンボックスの記事を書くかなー ・おっぱい漫才？ ・NetFlixでまだ何も見てない ・稲田さんも出てるのかな？

HEALTH NEWS   Review finds blueberry and grape polyphenols may improve vascular health Plant compound shows promise for treating rheumatoid arthritis at its source, study finds Screen Time at Ages 1 and 6 Linked to Lasting Learning and Memory Effects Some caffeinated drinks are linked to poorer memory Study: Morning Exercise Linked to Lower Daily Calorie Intake Compared to Evening Workouts   Review finds blueberry and grape polyphenols may improve vascular health Universidad Católica de Murcia (Spain), July 27 2026 (News-Medical) A recent review published in the journal Nutrients examined the evidence on the effects of blueberries, grapes, and their bioactive compounds on cardiovascular risk markers. In the present study, a comprehensive systematic literature search was conducted to identify randomized controlled trials (RCTs), systematic reviews, and meta-analyses published from January 2015 through April 2026.  Two systematic reviews and meta-analyses reported that grape polyphenols at doses exceeding 500 mg/day for at least 12 weeks significantly reduced C-reactive protein levels, while the other reported improvements in vascular function or BP in 84% of the human studies it assessed, including a significant reduction in systolic BP. One found a modest reduction in BP and improvement in endothelial function with flavan-3-ol foods, such as tea, apples, cocoa, and grape-derived products. Moderate- and high-quality RCTs reported improvements in lipid peroxidation, lipid profiles, flow-mediated dilation, diastolic BP, and paraoxonase activity. Resveratrol and blueberry RCTs mainly reported endothelial and vascular benefits, such as improved nitric oxide production and flow-mediated dilation and reduced BP and inflammatory markers. One high-quality RCT involving older men with metabolic syndrome showed significant improvements in arterial stiffness and endothelial function after six months of daily blueberry consumption.     Plant compound shows promise for treating rheumatoid arthritis at its source, study finds Guangzhou University of Chinese Medicine, July 27 2026 (Natural News) A plant-derived compound called obakulactone (OL) reduced swelling, inflammation and joint damage in rats with rheumatoid arthritis, according to a study published in Engineering.   The compound, a tetracyclic triterpenoid from the bark of Phellodendri cortex, also rebalanced immune activity and corrected disrupted fatty acid metabolismd. P. cortex has been used in traditional medicine and contains OL along with other constituents, Researchers tested OL in rats with rheumatoid arthritis, administering low, medium and high doses for 21 days. Treatment significantly reduced joint swelling and helped restore the normal structure of cartilage and the synovium, the tissue lining the joints, according to the report.   Blood tests showed dose-dependent decreases in inflammatory molecules including IL-1, IL-6, IL-17 and TNF, as well as rheumatoid arthritis markers RF, CCP-Ab, CRP and MMP-3, officials said. The compound also reduced abnormally high levels of CD3+ T cells and CD68+ macrophages within the joints and shifted macrophages from a proinflammatory M1 state toward an anti-inflammatory M2 state.   Screen Time at Ages 1 and 6 Linked to Lasting Learning and Memory Effects National University of Singapore & Zhejiang University (China), July 28, 2026 (SciTech Daily) A study that tracked children from age 1 through age 8 found that greater screen viewing time, especially during infancy and near the start of school, was associated with lower academic performance at age 9 and weaker working memory at age 10.5. The results indicate that when children use screens may matter as much as how long they spend using them. The World Health Organization (WHO) and the American Academy of Pediatrics advise avoiding screens before 18 to 24 months and limiting viewing to less than one hour per day between ages 2 and 5. Many children exceed those recommendations, yet previous research on screens and cognitive development has produced inconsistent results. The analysis included 502 children followed from infancy into middle childhood. Higher screen viewing during particular stages was associated with poorer academic results and weaker working memory later on. The clearest and most consistent relationships appeared during infancy and near school entry, suggesting that these may be especially sensitive periods for cognitive development. Children with greater total screen exposure across childhood also generally performed less well in school. Together, the findings suggest that both the timing and overall amount of viewing may have implications for learning and memory.   Some caffeinated drinks are linked to poorer memory Applied Science Private University (Jordan), July 28 2026 (News-Medical) A recent study in the Journal of Education and Health Promotion examined the association between caffeine-containing products and memory performance, anxiety, and stress among university students in Jordan. 204 students were ultimately included in the study.  Mild psychological distress was the most common category, with 38.2% reporting such symptoms. About four in ten reported mild depression, and over a quarter experienced moderate anxiety. Only a small minority showed severe or extremely severe stress. Caramel or nut-filled chocolate was the most frequently consumed item, reported by 54.9% of students, followed by Arabic coffee (40.2%) and red tea (35.8%). Milk chocolate was also popular, typically consumed once or twice a day. Dark chocolate was less common, while American coffee and green tea were less popular, and decaffeinated coffee was rarely chosen. Overall DASS scores, representing depression, anxiety, and stress symptoms, showed positive correlations with the consumption of dark chocolate, American/instant coffee, decaffeinated coffee, and red tea, indicating these items were linked to higher psychological distress scores. Memory ability was negatively associated with higher intake of American coffee, Arabic coffee, and soft drinks.  The authors note that chocolate and green tea also contain bioactive compounds such as cocoa flavanols and L-theanine, which may have contributed to these associations alongside caffeine.   Study: Morning Exercise Linked to Lower Daily Calorie Intake Compared to Evening Workouts Copenhagen University Hospital (Denmark), July 27 2026 (Natural News)   A new study has found that morning exercise was associated with lower calorie consumption throughout the day compared to evening workouts, according to the research. Participants who exercised in the morning consumed about 400 fewer calories at the post-workout meal and roughly 547 fewer calories over the full 24-hour period, the study reported.   The study, which involved 35 healthy young adults. Each participant completed 30 minutes of treadmill running multiple times under varying conditions: morning fasted, evening fasted for 12 hours or 6 hours, and morning or evening fed, the study stated. The repeated-measures design enabled researchers to compare the same person's responses across different scenarios, officials said. After evening sessions, participants reported higher hunger, a stronger desire to eat, and lower fullness compared to morning sessions, the study found. Those who worked out in the evening consumed about 400 more calories at the post-workout meal and roughly 547 more calories over the full day, according to the research.   The appetite advantage was attributed to circadian rhythms, researchers said. The hunger hormone ghrelin naturally rises in the evening, while satiety hormones are more active in the morning,.

出演者： miko、quim 配信ペース： 隔週 番組時間：86分40秒 ♯本番組はリモート収録です。 ♯収録時環境の影響により、全体的に聴き取り辛くなっております。 　申し訳ございません。 隔週に1回お届け。mikoラジ、第402回です。 我さん、遂にお仕事を○○に?! しがないさん、エンジンブレーキとサイドブレーキが……。 隔週でも話すことは尽きないふたりがお届けするお家ラジオ、 400回を越えても平常運転です。 最後までごゆるりとお楽しみくださいませ。 ♯途中で色々とノイズ等入りますが、収録時のものです。 　ご安心ください、お手持ちの機器は正常です。 ・おとらってRECORD 公式サイト http://www.n-remix.com/otolatte/ ↑『おとらって10thライブ KUWANA』に参加予定の方は、 　「来場予約はこちらから」からご予約を！ 開催日／2026.8.23(日) 　第一部　OP11:30　ST12:00 　第二部　OP14:40　ST15:00 //////////////////// VOICEVOX:ずんだもん VOICEVOX:四国めたん //////////////////// -------------------- ●お便り募集中！ mikoラジでは以下の内容でお便りを募集中です！ ・ふつおた 　／普通のお便り、お待ちしています！ ・mikoは大変な絵を描いていきました 　／miko画伯に描いて欲しいお題をお待ちしています！ ・メシヲコエテ 　／料理人・mikoに教えて欲しいレシピをお待ちしています！ bit.ly/2GAWjyv 投稿フォームからラジオに投稿が出来ます！ コーナー名を選び、メッセージ・ラジオネーム・お所を入力して、 どんどん送ってください！　お待ちしています！！ ------------ 本ラジオのメインパーソナリティーである「チーム我等(miko/quim)」、 それぞれ以下個人サークルにて活動中です。 ・miko：miko ・quim：SHIGANAI RECORDS（ shiganai.com/ ） 活動詳細については、上記HPの他 各人のブログ/twitter等にて随時告知しておりますので、チェックしてみてください！ ・みころぐ。(mikoのブログ)（ ameblo.jp/miko-nyu/ ） ・@ mikonyu(mikoのtwitter)（ twitter.com/mikonyu ） ・@ quim(quimのtwitter)（ twitter.com/quim ） --- その他の活動については、以下のとおりです！ -- チーム我等がメインクルーとして活動していた「アルバトロシクス（ albatrosicks.com/ ）」、 これまでリリースしたCDは、イオシスショップ（ iosys.booth.pm/ ）にて頒布しております。ご興味ある方は是非！ ---------- ☆2026年7月IOSYSはいてない.comパワープレイ楽曲 M1. Comeback 作編曲：HiroHiro & Smeets 音楽ジャンル：Happy Hardcore, UK Hardcore サークル：Notebook Records 収録アルバム：YATSUZAKI HARDCORE COLLECTION 17 2026・7・1 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-017 YATSUZAKI HARDCOREが贈る「YATSUZAKI HARDCORE COLLECTION」シリーズ第17弾！ ハイクオリティな直球UK Hardcoreコラボレーションが直撃！"HiroHiro & Smeets - Comeback" ジャパニーズカワイイカルチャーが生み出した次世代ポップコア"10den - Dear" 動きのデカさを感じさせるハードコアトラック"ZEPHYR - Celestia" ピュアでクレイジーな狂気が一心不乱にちょっかいをかけてくる"hitogomi - Nutty as a fru!tcake" 4組による書き下ろしトラックが収録！

It's EV News Briefly for Friday 24 July 2026, everything you need to know in less than 5 minutes if you haven't got time for the full show.Patreon supporters fund this show, get the episodes ad free, as soon as they're ready and are part of the EV News Daily Community. You can be like them by clicking here: https://www.patreon.com/EVNewsDailyVOLKSWAGEN OPENS UK ORDERS FOR TRANSPORTER EHYBRIDVolkswagen has opened UK orders for its first Transporter plug-in hybrid, badged eHybrid, offered in panel van, Kombi and Shuttle bodystyles with a 2.5-litre petrol engine, electric motor and 11.8kWh battery delivering 232PS and up to 35 miles of electric range. Prices start at £38,155 excluding VAT, and the van shares its Ford Transit Custom-derived plug-in hybrid platform while retaining a 1,132kg payload and 2,300kg towing capacity.GERMAN BEVS GOT CHEAPER, NOT PRICIERA study by ICCT and Fraunhofer ISI found that comparable battery EVs in Germany fell about 18% in real terms between 2020 and 2025, even though average list prices rose from roughly €37,000 to €53,000 due to larger, better-equipped models. Battery costs dropped 21-24% nominally over the period, but manufacturers mostly reinvested those savings into extra range and R&D rather than passing them fully to buyers.FORD APPROVES F-150 HOME BACKUP SWITCHFord has approved Global Power Products' GenerLink transfer switch for F-150 Lightning and PowerBoost Hybrid owners, letting Pro Power Onboard feed a home's main electrical panel directly without extension cords. The hardware costs $1,100 plus installation fees of $250-$1,500, positioning it as a cheaper alternative to Ford's automatic wall-charger-based backup system.NISSAN LEAF NISMO LAUNCHES IN JAPANNissan has launched the Leaf Nismo in Japan starting July 22, with North America and Europe to follow later; it keeps the standard 160kW/214hp motor and battery but adds recalibrated software for about 20% stronger initial acceleration, plus suspension, tyre and aerodynamic upgrades. Pricing starts at ¥6.60 million (~$40,600), rising to ¥7.23 million (~$44,510) for the weight-saving Recaro edition.SILA RAISES $300 MILLION FOR US ANODESSila has raised $300 million to expand production of its Titan Silicon silicon-carbon anodes, which it claims can boost EV range by up to 20% and energy density by 20-40% with faster charging. Its Moses Lake, Washington factory is scaling toward 250 GWh of annual capacity within five years, with customers including Mercedes-Benz and Panasonic Energy already signed up.MILENCE OPENS ZERO-EMISSION BUILT HENGLO TRUCK HUBMilence has opened its fourth Dutch heavy-duty charging hub, at Deurningen-Hengelo on the A1, notable as the company's first built entirely using zero-emission construction machinery. The site offers five 400kW CCS bays plus rest facilities, and Milence, backed by Daimler Truck, Traton and Volvo, plans to replicate the all-electric construction approach at future hubs.SPECTRE CLIMBS AS ROLLS-ROYCE KEEPS V12The Rolls-Royce Spectre became the brand's second best-selling model worldwide in 2025, drawing a younger buyer base and showing little resistance from existing V12 customers, according to sales director Julian Jenkins. Despite this EV momentum and an upcoming Spectre Series II with 500kW output and 628km range, Rolls-Royce has dropped its 2030 V12 phase-out plan, citing regulatory changes, and will keep selling both powertrains.GRIDSERVE OPENS FIFTH ELECTRIC FORECOURT AT M1GRIDSERVE has opened its fifth Electric Forecourt at Markham Vale on the M1, featuring 39 ultra-rapid 400kW ABB charging bays, solar panels and rainwater harvesting, bringing its national network past 200 sites. The launch follows a record first half of 2026 in which battery electric vehicles reached about 24.9% of UK new car registrations.HOME CHARGING LEAVES RAPID NETWORK UNDER STRAINA YouGov survey of 2,086 EV drivers found 74.6% use public chargers only once every few months or less, reflecting that 91% of EV owners can charge at home where off-peak tariffs can fall to 7p/kWh versus 87p/kWh for public rapid charging. This heavy reliance on home charging is squeezing public chargepoint operators financially, even as rapid chargers remain essential for longer journeys.AUSTRALIA POST GETS $40.5M FOR HEAVIER EVSAustralia Post will receive a $40.5 million federal investment in 2026-27 to add electric vans, trucks, prime movers and depot charging infrastructure, building on its existing fleet of over 5,000 electric vehicles. The move aims to cut diesel use by about 1 million litres a year while supporting a delivery network handling 2.2 billion parcels annually.AVILOO EXPANDS USED EV BATTERY WARRANTY NORTHAviloo has extended its used EV Battery Warranty to Norway and Denmark, adding to ten existing European markets, using its three-minute Flash Test to set an individual State of Health threshold for each vehicle. If a covered battery falls below that threshold within a year, buyers receive compensation of up to 34,000 kr in Norway or 23,000 kr in Denmark, plus a refund of the test cost.

ぬるぽ放送局おたより投稿フォーム https://forms.gle/6tbmBzK6wbyavJG47 2026年7月パワープレイ M1. Comeback 作編曲：HiroHiro & Smeets 音楽ジャンル：Happy Hardcore, UK Hardcore サークル：Notebook Records 収録アルバム：YATSUZAKI HARDCORE COLLECTION 17 2026・7・1 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-017 番組時間：81分3秒 出演者：夕野ヨシミ、たくや VOICEVOX:ずんだもん VOICEVOX:四国めたん ---- 2026/7/23に公開録音したものを配信いたします。 ラジオ記事はリスナーのEEチャンピオンさんが書いてくれているので楽してます。 ＜オープニング＞ ・秋のトークライブイベントがあるんですよ ・今日は素数かな？ ・33の二乗だって ・景気がいいからみんなにトークライブのチケットを買ってもらおう ・夏将軍本気出し過ぎ ・45℃超えたら新しい名前決めなきゃ ・まじで塩分摂って ・イオシスくんの活動報告 ・楽曲提供しました！ 　Nintendo Switch『グルーヴコースター フューチャーパフォーマー　ズ』 　「Dive in glory!」 　作詞、ベース：john=hive (IOSYS) 　作曲、編曲：コバヤシユウヤ (IOSYS) 　ギター：三浦公紀 　ボーカル：尾流渦キララ(CV: のぐちゆり) 　2026/7/23配信開始です ・リミックス提供しました！ 　『ブレイクマイケース』 　「just what I see(Remixed by IOSYS TRAX)」 ・2026/7/23リリース『hololive Dreams』 　IOSYS提供楽曲が遊べます！ 　「ぎゅーどんかーにばる！／白銀ノエル」 　「Ahoy!! 我ら宝鐘海賊団☆／宝鐘マリン」 　「地獄で会おうぜ！ スバちょこるなたん／スバちょこるなたん」 　「みっころね×しょうたいむ!!／さくらみこ, 戌神ころね」 ・ホロドリやった方がいいですよ ・はじめるなら今！ ・7/25　プロ野球ファンの集い ・8月からイオメンマルチプレイやります ・なんとかファクトリオかなー ・今後のアップデートがない ・全員真顔の客 ・また海外行くのまろんくん？ ・8/16　イオパ　北海盆踊り回 ・たまにあるブルアカの長い生放送 ＜Aパート＞ ・ピザプランご支援よろしくお願いします ・はかせは5人いる ・ふつおたです ・好きなそばメニュー ・冷たい肉そば ・肉と言っても鶏肉 ・ぬるいのでお願いします（めんどくさい客） ・アツアツのモバイルバッテリーはいかがですか？ ・薄いバッテリーが厚くなる ・ノンフライヤー買いました ・いつ箱から出すのか　レビュー待ってます ・12年ぶりのゴンさん ・最近のハンターハンターに後方彼氏顔の夕野さん ・MOCさんは活動20周年ってことにしときました ・枠を埋めてもらうと前川さんがよろこびます ・手作りしょうゆ動画は編集中です ・農家の心の窓 ・機械のために農家やってたのか ・3時半に起こして ・パンパンのペットボトルが道端に ・ボトラーのみなさん ・怖い黄色いお茶 ・これは不法投棄とかですよね？ ・また、漏らしたお便り来てますよ ・台所の水漏れ ・ロフトが崩壊？ ・札幌にゴキブリが ・ねこは日本語がわかる ・来年結婚します ＜Bパート＞ ・みつをたです ・お姉さんtier表配信 ・大家さんのコスプレが本人すぎる稲田徹さん ・だんだん覚えていくサイゼリヤのメニュー番号 ・にじさんじピックアップニュース ・ギリギリ覚えられるラインがギリギリ過ぎる ・10分で崩壊するチルラジオ ・パンティーを履くと礼儀正しくなる ・ピックアップニュースからピックアップ ・よそのラジオからコーナーパクって来るか ・井上陽水LINEスタンプってあるのかな？ ・ホロピックアップニュース ・ラプだもん ・ホロドリをみんなやってます ・Vピックアップニュース ・すべてねぎしでやっつけろ ・スーパーの裏でねぎし食べるふたり ・よろしくメカねぎし ・健康診断の後は牛タン食べました ・マダム「ねぎしを食べに行きましょう」 ・しょうゆ片手にサウナに入らないと ・塩対応 ＜エンディング＞ ・情報収集の10割がTwitterって ・マックの炙り醤油ソース抜きはホントにおいしいのでやってください ・お便りお待ちしてます

We hold these Monthly Virtual Interactive Conferences so that we can engage with our listeners locally, nationally and internationally and encourage them to join the Grass Roots Community Activist Movement. We also want to raise funds for our film project "Hood Liberator Made In Chicago: The War Against Willie Lynch Begins" This film project is my last attempt to try to do something positive for my racial group Black Americans who identify as (DAS-FM) Descendants of American Slaves/Freedmen. We host our Monthly Virtual Interactive Conference on the last Saturday of the month. We're trying to raise $250 thousand dollars so that we can make a quality Black Empowerment Film based on my experience growing up in the inner cities of Chicago and having to endure all kinds of push back from Black Chicago for trying to get my Black Christian business up and running in the Black Community. I want to encourage seasoned Black American Film Makers and African Film Makers from across the United States of America to consider working with us in getting this film fully funded and made because it is needed now more then ever. #NotAnother34Years, #M1, #DAS-FM, #JoinGRCAM

Ukrainā jauna ministru kabineta veidošana ir nonākusi līdz protestiem un armijas virspavēlnieka Oleksandra Sirska nomaiņai. Savukārt Ukrainas triecieni Krievijas teritorijā nu jau skar ne tikai militāros un enerģētikas objektus, bet arī tirdzniecības vietnes "Wildberries" noliktavas. Lielbritānija tikmēr tikusi pie sava nākamā premjera - leiborista Endija Bērnema, kurš Dauningstrītā ieradies, pamatīgi izsvēpējot stārmera veidoto kabinetu. Bet Ungārijā "buldozera lomu" uzņēmies jaunais valsts premjers Pēters Maģars, kurš dažādos valsts līmeņos un struktūrās mēģina izsvēpēt Viktora Orbana laikmeta paliekas. Šos tematus apspriežam kopā ar Martu Eduardu Ivaski no Latvijas Ārpolitikas institūta un portāla "LSM.lv" ārvalstu ziņu redaktoru Ģirtu Kasparānu. Zelenskis nevar, kā ienāk prātā Kad aizpagājušās nedēļas beigās parādījās informācija par līdzšinējās Ukrainas valdības atkāpšanos un jauna kabineta veidošanu, sākotnēji nekas neliecināja, ka process varētu draudēt ar krīzi. 16. jūlijā Ukrainas Augstākā Rada apstiprināja valdību ar līdzšinējo valsts naftas un gāzes koncerna „Naftogaz” vadītāju Serhiju Korecki priekšgalā. Taču saskaņā ar Ukrainas likumdošanu aizsardzības un ārlietu ministru kandidātus izvirza prezidents, un par viņiem Rada balso atsevišķi. Jau valdības apstiprināšanas laikā Kijivas ielās bija sākušies protesti, jo bija parādījusies informācija, ka amatam netiks atkārtoti izvirzīts populārais aizsardzības ministrs Mihailo Fedorovs. Protestētāji izvirzīja arī prasību atcelt no amata līdzšinējo armijas pavēlnieku ģenerāli Oleksandru Sirski. Pastāv viedoklis, ka Ukrainas pašreizējie panākumi kaujas robotu izmantošanā lielā mērā ir ministra Fedorova nopelns, savukārt ģenerālis Sirskis kā „vecās skolas” virsnieks drīzāk kavē šo attīstību. Nākamajās dienās protesti vērsās plašumā un aptvēra arī citas Ukrainas pilsētas. Vakar, 21. jūlijā, prezidents Zelenskis paziņoja, ka atceļ no amata ģenerāli Sirski, par jauno pavēlnieku ieceļot ģenerālmajoru Mihailo Drapatiju. Savukārt bijušajam aizsardzības ministram Mihailo Fedorovam piedāvāts jaunizveidots tehnoloģiju un militāro inovāciju ministra portfelis. Par aizsardzības ministra pienākumu izpildītāju iecelts drošības spēku ģenerālmajors, kopš šī gada sākuma arī Ukrainas Drošības dienesta priekšnieka pienākumu izpildītājs Jevhenijs Hmara. Nedienas ar aizsardzības ministra izraudzīšanos aizkavējušas arī ārlietu resora vadītāja apstiprināšanu, un līdzšinējais ministrs Andrijs Sibiha, kuram, visdrīzāk, vajadzēja saglabāt amatu, pagaidām to ieņem pagaidu pienākumu izpildītāja statusā. Neskatoties uz diezgan juceklīgo situāciju, Augstākā Rada tomēr nolēmusi doties plānotajās brīvdienās līdz 18. augustam. Jaunumi ukraiņu lidrobotu „ēdienkartē” Pēdējās dienas papildinājušas Ukrainas lidrobotu triecienu „ēdienkarti” ar jaunu objektu kategoriju: nedēļas nogalē uzlidojums praktiski iznīcinājis divus tīmekļa tirdzniecības tīkla „Wildberries” noliktavu kompleksus – vienu Piemaskavā, otru Tambovas apgabalā. Iespējami zaudējumi pārsniedz divus miljardus dolāru, astoņi noliktavās strādājošie zaudējuši dzīvību, desmitiem ievainoti. „Wildberries” ir lielākais šāda veida komercijas tīkls Krievijā, kurā nodarbināti gandrīz piecdesmit tūkstoši strādājošo. Kompāniju pirms vairāk nekā divdesmit gadiem radīja individuālā uzņēmēja Tatjana Kima, taču, kā tas mēdz notikt ar sekmīgiem uzņēmējdarbības projektiem Krievijā, pirms vairākiem gadiem viņai nācās „padalīties” ar varas aprindām pietuvinātiem ļaudīm. Pie tam par pīrāga daļu saplūcās tādi ietekmīgi ļaudis, kā Čečenijas vietvaldis Ramzans Kadirovs no vienas un Krievijas Prezidenta administrācijas vadītājs Antons Vaino un oligarhs Suleimans Kerimovs no otras puses. Notika pat apšaude ar kritušajiem Maskavas centrā, un, cik var spriest, procesā iejaucās pats Vladimirs Putins, izšķirot to par labu Vaino un Kerimova frakcijai. Ievērojot šīs saiknes ar varas struktūrām, nenākas brīnīties, ka „Wildberries” sortimentā plaši pārstāvēti arī karā lietojami izstrādājumi un materiāli: ķiveres, bruņu vestes, optiskais kabelis un plašs klāsts lidrobotu komponentu. Tādējādi Ukrainas lidrobotu „vizīte” bija, var teikt, tikai laika jautājums. Jāpiebilst, ka „Wildberries” loģistikas ķēdes un noliktavas plaši izmanto mazie un vidējie uzņēmēji, un ir tādi, kuri šais uzbrukumos zaudējuši praktiski visus apgrozāmos līdzekļus. Dauningstrītas 10 jaunais iemītnieks Pirmdien, 20. jūlijā, darbu uzsāka jaunais Lielbritānijas premjerministrs Endijs Bērnems. Viņu Leiboristu partija 17. jūlijā izraudzījās par savu jauno līderi pēc tam, kad viņa priekšgājējs Kīrs Stārmers paziņoja par demisiju. Saskaņā ar britu politisko sistēmu šādā gadījumā valdošās partijas iekšējā balsojumā tiek izraudzīts jauns partijas un valdības vadītājs, un līdzšinējais Lielās Mančestras lordmērs Bērnems guva pārliecinošu savu partijas biedru atbalstu. Bērnems ieguvis mākslu maģistra grādu angļu valodas specialitātē Kembridžas universitātē, strādājis par žurnālistu, 31 gada vecumā pirmoreiz ievēlēts parlamentā. Neilgi pēc tam Bērnems ieņēma vairākus ministra amatus premjerministra Gordona Brauna valdībā laikā no 2007. līdz 2010. gadam. Pēc aiziešanas no parlamenta 2017. gadā Bērnems tika ievēlēts Lielās Mančestras mēra amatā, kur ieguva atzinību par transporta reformu vadīšanu, reģionālās decentralizācijas atbalstīšanu un nozīmīgu vietējo politikas iniciatīvu īstenošanu. Tieši šajā amatā viņš nostiprināja savu reputāciju kā politiķis, kurš iestājas par lielāku varas nodošanu reģioniem un vietvarām, un izpelnījās pavārdu „Ziemeļu karalis”. Stājoties amatā, jaunais premjerministrs uzsvēris cenšanos veidot savu komandu, iekļaujot tajā dažādu partijas spārnu pārstāvjus. Tomēr, kā atzīmē izdevums „Politico”, no valdības pazuduši iepriekšējā premjera tuvākie līdzgaitnieki un kopumā tā kļuvusi mērenāk kreisa. Jaunais finanšu ministrs būs Džons Hīlijs, kurš iepriekšējā valdībā bija aizsardzības ministrs un demisionēja, kritizēdams finanšu sektoru par attīstības bremzēšanu. Aizsardzības ministra amatu, savukārt, ieņems līdzšinējais veselības ministrs Vess Strītings. Ārlietu resoru turpmāk vadīs līdzšinējais enerģētikas un nulles emisiju lietu ministrs Eds Milibends, prominents un pieredzējis politiķis. Luīze Heiga, kas tiek raksturota kā viena no ciešākajām jaunā premjera sabiedrotajām, kļuvusi par pirmo sekretāri, respektīvi, premjera vietnieci, un Kabineta biroja vadītāju. Savā pirmajā premjera runā Bērnems uzsvēra decentralizācijas, rūpniecības un sabiedrisko pakalpojumu attīstības nozīmi, atspoguļojot prioritātes, kuras viņš iepriekš īstenoja kā mērs un pats nodēvējis par “mančestrismu”. Ārpolitikā Bērnems ir paudis vēlmi veidot ciešāku sadarbību un nostiprināt jau panākto progresu sarunās ar Eiropas Savienību. Premjerministrs atkārtoti apstiprināja Lielbritānijas atbalstu NATO un palīdzības sniegšanu Ukrainai. Pagaidām grūti spriest, kādas izvērtīsies jaunā Dauningstrītas iemītnieka attiecības ar Donaldu Trampu, kas lielā mērā noteiks arī attiecības starp Londonu un Vašingtonu. Diezin vai paredzama nozīmīga britu nostājas maiņa Persijas līča karadarbības vai imigrācijas jautājumā, kas varētu Baltā nama saimnieku īpaši iepriecināt, taču pirmā abu līderu telefonsaruna esot atstājusi pozitīvu iespaidu. Sagatavoja Eduards Liniņš un Artis Tomsons. Pētera Maģara sprints un barjerskrējiens Vēl nav pagājuši trīs mēneši, kopš Ungārijas premjerministra amatā stājās Pēters Maģars, taču valsts iekšpolitiskajā ainavā un ārpolitiskajā kursā notikušas krasas un sagaidāmas pārmaiņas. Vēlēšanas nesa partijai „Tisza” ne vien uzvaru, bet arī konstitucionālo vairākumu, un tas dod jaunajai valdībai diezgan labu atvēzienu, mēžot priekšgājēja, odiozā prokremliskā līdera Viktora Orbāna 16 varas gados piekrātos „Augeja staļļus”. Tūlītējas un pamanāmas pārmaiņas notika Ungārijas ārpolitikā. Pagājušajos pāris mēnešos jaunais Ungārijas līderis jau paguvis apmeklēt daudzas Eiropas galvaspilsētas. Briselē viņš panācis līdz šim iesaldēto vairāk nekā 16 miljardu eiro fondu saņemšanu, Varšavā atjaunojis labas attiecības ar nozīmīgāko reģionālo partneri Poliju, Kijivā vienojies, ka Budapešta vairs nebloķēs Ukrainas virzību uz Eiropas Savienību, pretim saņemot konkrētas apņemšanās Ukrainas Aizkarpatu reģionā mītošās ungāru minoritātes situācijas uzlabošanai. Taču, kā savā rakstā izdevumā „Internationale Politik Quarterly” pauž Centrāleiropas valstu politikas eksperte Žužanna Vēga, ja Petera Maģāra līdzšinējā starptautiskā darbība esot īsts sprints, tad viņa iekšpolitika drīzāk ir barjerskrējiens. Jaunajam valdības galvam nākas demontēt un reformēt varas mehānismus, kurus viņa priekšgājējs sabūvējis savas politiskās konjunktūras labā. Eiropas fondu atsaldēšana kļuvusi iespējama pirmām kārtām pateicoties gatavībai skaust partijas „Fidesz” laikā sazēlušo korupciju un necaurspīdīgumu to izlietojumā. Spilgta ir jaunās valdības rīcība, reformējot Ungārijas sabiedriskos raidītājus, kurus iepriekšējā vara bija pārvērtusi valdošās partijas propagandas mašīnā. Kopš jūlija sākuma sabiedriskās televīzijas ziņu kanālā M1 raidījumu vietā skatītājus sagaida tumšs ekrāns ar uzrakstu: „Sabiedriskie mediji nedrīkst melot. Lūdzam piedošanu, ka to tik ilgi darījām!” Seko informācija par notiekošo mediju reformēšanu un aicinājums gaidīt pārraižu atjaunošanos. Orbāns un partija „Fidesz” savas varas gados praktiski visur amatos savietojusi savējos, kuri daudzos gadījumos sagaidāmi sabotēs pārmaiņu procesus. Premjerministrs Maģars aicinājis daudzus iepriekšējā konjunktūras ielikteņus labprātīgi aiziet, sākot jau ar līdzšinējo Ungārijas prezidentu Tamāšu Šujoku. Kad valsts galva atteicās to darīt, parlaments 13. jūlijā pieņēma konstitūcijas grozījumus, kas paredz, cita starpā, prezidenta pilnvaru izbeigšanu. 18. jūlijā prezidents Šujoks šos labojumus apstiprināja, tādējādi piekrizdams aiziet. Tagad Ungāriju gaida ārkārtas prezidenta vēlēšanas. Vairāki ievērojami sabiedrības pārstāvji nākuši klajā ar publisku vēstuli, aicinot partiju „Tisza” nominēt valsts galvas amatam izcilo šahisti, pašreizējo Pasaules šaha federācijas sieviešu reitinga līderi Judīti Polgāru. Tomēr viņa laipni atteicās no nominācijas. Sagatavoja Eduards Liniņš.  

Depuis l'arrivée de la puce M1 en 2020, Apple avançait avec un calendrier presque parfaitement régulier. Mais cette mécanique semble désormais s'emballer. Selon Mark Gurman, de Bloomberg, la firme aurait déjà terminé la conception de sa puce M7, seulement six mois après celle de la M6, alors même que les premiers produits équipés de cette dernière ne sont pas attendus avant la fin de 2026.La feuille de route reste officieuse, Apple n'ayant rien confirmé. Les premiers Mac dotés d'une puce M6 arriveraient donc à la fin de cette année, avant une génération M7 dès le début de 2027. Les versions M7 Pro et M7 Max suivraient à la fin de 2027, puis le M7 Ultra en 2028. La génération M6 pourrait ainsi connaître une carrière particulièrement courte. Apple aurait même abandonné les versions M6 Pro et Max afin d'accélérer le passage à la génération suivante. Pour Mark Gurman, cette cadence montre surtout que l'intelligence artificielle ne constitue plus une simple fonction ajoutée aux processeurs Apple : elle influence désormais directement leur architecture et leur calendrier de développement.Le chiffre le plus spectaculaire concerne la mémoire. Le futur M7 Ultra serait conçu pour gérer jusqu'à 1,5 téraoctet de mémoire unifiée. Dans les Mac Apple Silicon, cette mémoire est partagée entre le processeur central et la puce graphique, ce qui facilite le traitement de charges lourdes. Une telle capacité représenterait environ le double de celle envisagée pour le M5 Ultra et l'équivalent de la mémoire de 96 MacBook Air d'entrée de gamme réunis. Mais rien ne garantit qu'Apple commercialisera réellement cette configuration. La décision dépendra du marché des composants, alors que la mémoire reste rare et coûteuse. Tim Cook a déjà justifié de récentes hausses de prix des Mac par l'augmentation du coût de la RAM.Une machine équipée de 1,5 téraoctet cumulerait donc tous les facteurs inflationnistes : beaucoup de mémoire, sur un composant cher, dans un produit très haut de gamme. Aucun prix n'a filtré, mais les options mémoire d'Apple sont déjà coûteuses en temps normal. Le Mac Studio devrait, lui, attendre 2028 pour sa véritable transformation. La version M5 Ultra prévue cette année serait surtout une évolution mineure. Le futur modèle pourrait adopter un nouveau design et un refroidissement renforcé pour supporter les traitements d'intelligence artificielle réalisés directement sur la machine. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

ぬるぽ放送局おたより投稿フォーム https://forms.gle/6tbmBzK6wbyavJG47 2026年7月パワープレイ M1. Comeback 作編曲：HiroHiro & Smeets 音楽ジャンル：Happy Hardcore, UK Hardcore サークル：Notebook Records 収録アルバム：YATSUZAKI HARDCORE COLLECTION 17 2026・7・1 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-017 番組時間：83分28秒 出演者：夕野ヨシミ、たくや VOICEVOX:ずんだもん VOICEVOX:四国めたん ---- 2026/7/16に公開録音したものを配信いたします。 ラジオ記事はリスナーのEEチャンピオンさんが書いてくれているので楽してます。 ＜オープニング＞ ・夕野さんどこに行ってたんですか？ ・ねぎしチュール ・池袋にサウナに行ってきました ・ホントはイベント前にご飯食べないでほしいな ・イベント用のしょうゆ出来てます ・ぺロッ…これはしょうゆ ・味見で半分残ればいいんですけどね ・10/24阿佐ヶ谷で味見できます ・飲み過ぎたのはヨシミのせいよ ・今週1週間なにもありませんでした ・メズラシイネ ・マクスウェルのパズルな悪魔がやばい ・台風一過ってことですね ・いきなりトイストーリー５から見ちゃう ・え？音響マンになりつつある？ ・千葉から追っかけが ・ひとのでんわ展行ってきました ・察するゲームなのかい ・飛行機ってなんであんなに遅れるんですか？ ＜Aパート＞ ・ふつおたです ・突合なんて、ITおじさんしか使わないよ ・北海道はあの広さで1道なんだぞ ・ついにネットフリックス ・地面師のヨシミ ・水曜もうええでしょう ・ジャンプ売り切れ ・ハンターハンターが読める幸せ ・ハンターハンター専用SNS ・初老の飲み会の報告 ・はかせが体調不良 ・前川さんの上の人って限られてますよね？ ・はかせの息子の名前を誰も知らない ・一人くらい捕まった方が面白いかと ・ARM「しゃちょうってのに気をつけろよ」 ・お、雀魂！ ・ハコパーク ＜Bパート＞ ・夏に聞くとちょうどいい曲 ・鉄アレイが捗る曲 ・パワープレイ中は鉄アレイやってます ・みつをたです ・汗をかかない裏技でもあるのかな？ ・読書は最低限で ・エアコンの中古はどうなのか ・おまねこくん ・いいねしてありました ・麻雀ファイトガールやべーよね ・西村社長ーいいねしましたよー ・リポストはしないんかい ・寝起きヤシの木レベル12に ・これ、全部同じ流れか ・カナメストーンだ ・イオシスしか出ねーだろ！ ・にじさんじピックアップニュース ・小笠原で野生化したるんちょま ・当たり屋と被害者のてぇてぇ ・6年前の初コラボ日を結婚記念日にしよう ・夕野ヨシミVの姿も7周年 ・キンタマが2tあったらどうする？ ・見るものがあり過ぎて大変 ・自分たちの配信好き過ぎ ・キャベツは切ってるのを買ってます ・dpgkじゃないですか ・ホロピックアップニュース ・もんじゃっておいしいんですか？ ・それだとねぎし行っちゃう ・ホロライブコミケ出展決定 ・Vピックアップニュース ・イオンモール系ではない ・お世話になってる人がぬるぽに集結してる ・ベスト４からでもよくない ・ハーフタイムが30分 ・今日はヤニねこ見よう ＜エンディング＞ ・ハーフタイムでねぎしが食べれるね ・この番組はねぎしの提供でお送りしました（冗談です） ・スポンサー待ってますよ ・マクドナルドさんは来てくれましたね ・がんばれねぎし外伝　消えた黄金キセル　 ・シムねぎし ・ねぎし大喜利始まった

It's just Jem this week, mopping up the last suds of our post punk mini-series with a series of British bands who ripped it up and started again. We spend time with The Slits fantastic dub punk debut Cut, shouting out the production of the great Dennis Bovell on the way, then drive up the M1 to explore the rich pickings of that great musical city, Sheffield. With reference to an early Human League single, Jem unearths the imminent possibilities of the crumbling Fordist world. We hear two tracks from Public Image Ltd, before digging into one of our host's favourites - the Raincoats - to explore feminist aesthetics, Maoist China and an unlikely meeting with Kurt Cobain. We round out the piece with two classics from the mighty Clash. Not a bad haul for one year. We'll be away for a few weeks on various summer excursions, but will be back soon after with more music, dance floors, sound systems and counterculture. Tune in, turn on, get down!Patreon.com/LoveMessagePodhttps://www.loveisthemessagepod.co.uk/ Produced by Matt HuxleyTracklist: The Slits - Typical Girls The Slits - Adventures Close to Home Human League - Empire State Human Public Image Ltd - Death Disco Public Image Ltd - Socialist The Raincoats - Fairytale in the Supermarket The Raincoats - Lola The Clash - London Calling The Clash - Lost in the Supermarket Books:Audrey Golden - Shouting Out Loud: Lives of the Raincoats Frith & Horn - Art into Pop Reynolds & Press - The Sex Revolts: Gender, Rebellion and Rock'n'Roll

出演者： miko、quim 配信ペース： 隔週 番組時間：98分10秒 ♯本番組はリモート収録です。 ♯収録時環境の影響により、全体的に聴き取り辛くなっております。 　申し訳ございません。 隔週に1回お届け。mikoラジ、第401回です。 我さんの国外脱出（？）に伴い、配信スケジュールを変更して1週ズレての401回。 我さんの旅行のお話、しがないさんの対AI奮闘記（？）。 凄いことするな、何してんだろこの人達……そんな変わらぬ光景を今回もお届けいたします。 最後までごゆるりとお楽しみくださいませ。 ♯途中で色々とノイズ等入りますが、収録時のものです。 　ご安心ください、お手持ちの機器は正常です。 ・おとらってRECORD 公式サイト http://www.n-remix.com/otolatte/ ↑『おとらって10thライブ KUWANA』に参加予定の方は、 　「来場予約はこちらから」からご予約を！ 開催日／2026.8.23(日) 　第一部　OP11:30　ST12:00 　第二部　OP14:40　ST15:00 //////////////////// VOICEVOX:ずんだもん VOICEVOX:四国めたん //////////////////// -------------------- ●お便り募集中！ mikoラジでは以下の内容でお便りを募集中です！ ・ふつおた 　／普通のお便り、お待ちしています！ ・mikoは大変な絵を描いていきました 　／miko画伯に描いて欲しいお題をお待ちしています！ ・メシヲコエテ 　／料理人・mikoに教えて欲しいレシピをお待ちしています！ bit.ly/2GAWjyv 投稿フォームからラジオに投稿が出来ます！ コーナー名を選び、メッセージ・ラジオネーム・お所を入力して、 どんどん送ってください！　お待ちしています！！ ------------ 本ラジオのメインパーソナリティーである「チーム我等(miko/quim)」、 それぞれ以下個人サークルにて活動中です。 ・miko：miko ・quim：SHIGANAI RECORDS（ shiganai.com/ ） 活動詳細については、上記HPの他 各人のブログ/twitter等にて随時告知しておりますので、チェックしてみてください！ ・みころぐ。(mikoのブログ)（ ameblo.jp/miko-nyu/ ） ・@ mikonyu(mikoのtwitter)（ twitter.com/mikonyu ） ・@ quim(quimのtwitter)（ twitter.com/quim ） --- その他の活動については、以下のとおりです！ -- チーム我等がメインクルーとして活動していた「アルバトロシクス（ albatrosicks.com/ ）」、 これまでリリースしたCDは、イオシスショップ（ iosys.booth.pm/ ）にて頒布しております。ご興味ある方は是非！ ---------- ☆2026年7月IOSYSはいてない.comパワープレイ楽曲 M1. Comeback 作編曲：HiroHiro & Smeets 音楽ジャンル：Happy Hardcore, UK Hardcore サークル：Notebook Records 収録アルバム：YATSUZAKI HARDCORE COLLECTION 17 2026・7・1 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-017 YATSUZAKI HARDCOREが贈る「YATSUZAKI HARDCORE COLLECTION」シリーズ第17弾！ ハイクオリティな直球UK Hardcoreコラボレーションが直撃！"HiroHiro & Smeets - Comeback" ジャパニーズカワイイカルチャーが生み出した次世代ポップコア"10den - Dear" 動きのデカさを感じさせるハードコアトラック"ZEPHYR - Celestia" ピュアでクレイジーな狂気が一心不乱にちょっかいをかけてくる"hitogomi - Nutty as a fru!tcake" 4組による書き下ろしトラックが収録！

When a student freezes on a skill they've done a hundred times, what do you do? Dr. Leisha Strachan, sports psychologist and dance teacher, joins us to talk about the mental side of skill development, from breaking through blocks to managing performance anxiety. She covers practical tools like affirmations, breathing techniques, thought stopping, simulated practice, and imagery scripts that teachers can actually use in class. This is a Spotlight Series re-release of one of our most listened-to episodes, and it's easy to see why. A full transcript of the podcast is available here: https://www.acrobaticarts.com/blog/ep-139-mental-blocks-anxiety-and-self-talk Sources Referenced MindShift App AcroDance Resource Center Psyching for Sport - Terry Orlick The Mental Athlete - Kay Porter Sports Phsychology for Coaches www.projectscore.ca www.sportpsychologyforcoaches.ca About Dr. Leisha Stachan Dr. Leisha Strachan is a professor at the University of Manitoba with a research focus on positive youth development through sport. She is also interested in research with coaches and parents in the deliberate delivery of positive sport experiences for children and youth. Research Areas Positive youth development Sport participation Children Youth Sport psychology Education Doctor of Philosopy - Sport Psychology, Queen's University (2008) Master of Human Kinetics - Sport Psychology, University of Windsor (2004) Bachelor of Education, University of Manitoba (1999) Bachelor of Physical Education, University of Manitoba (1997) Leisha has been involved in sport and dance for the majority of her life. She began baton twirling at Crestview Community Club in Winnipeg at the age of 5 and continued for 18 years. She is a former Canadian Senior Freestyle Champion (1994), Grand National Solo and 2-Baton champion (1994), CBTF Senior Athlete and Overall Athlete of the Year (1994), and a 7-time Canadian Contingent member competing in freestyle (highest placing - 6th in 1994) and pair events garnering 2 world bronze medals for her efforts (with Kristin Macaraeg). In her time on the national team, she traveled to France, Japan, Holland, Italy, and Hawaii. Leisha is one of the founding coaches of Aerial Fusion Baton, which has been in existence for 25 years. In addition to being a Level 3 certified coach, she is also certified as a Module 1 teacher in Acrobatic Arts. She is also a certified M1, M2, M3, and Masters judge. She has had the opportunity to coach provincial and national team members and continues to choreograph for different athletes across Canada, England, and Scotland. IG @drls250 Previous Episodes Ep 4 Protecting Your Mental Health Dr Leisha Strachan Ep 31 Overcoming Dancer Anxiety + Mental Blocks with Dr. Leisha Strachan Ep. 69 Turning Dance Transitions into Triumphs with Dr. Leisha Strachan, Pt 1 Ep. 69 Turning Dance Transitions into Triumphs with Dr. Leisha Strachan, Pt. 2 Ep. 97 Mental Skills for Acro Success with Dr. Leisha Strachan Ep. 117 The Four C's Every Teacher Needs with Dr. Leisha Strachan

ぬるぽ放送局おたより投稿フォーム https://forms.gle/6tbmBzK6wbyavJG47 2026年7月パワープレイ M1. Comeback 作編曲：HiroHiro & Smeets 音楽ジャンル：Happy Hardcore, UK Hardcore サークル：Notebook Records 収録アルバム：YATSUZAKI HARDCORE COLLECTION 17 2026・7・1 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-017 番組時間：75分48秒 出演者：夕野ヨシミ、たくや VOICEVOX:ずんだもん VOICEVOX:四国めたん ---- 2026/7/9に公開録音したものを配信いたします。 ラジオ記事はリスナーのEEチャンピオンさんが書いてくれているので楽してます。 ＜オープニング＞ ・いよいよ夏です ・夏と言えばアイスクリーム ・D.wattはpinoが大好き ・眼精疲労で頭痛が ・二日酔いが原因なのでは？ ・イオシスくんの活動報告 ・「ROSE ～禁じられた愛～」 のMV毎日見てね ・楽曲提供しました！ 　『beatmania IIDX』2026/7/2～ 　「D.K.N. ON／RoughSketch」 ・ダケンオンであってると思います ・本人には確認しないんだ ・ゲーム実況はたくさんやってます ・ヤツコアもありました ・二日酔いの予約ってあるんですか？ ＜Aパート＞ ・食べなくても体重は減らない ・ふつおたです ・攻殻機動隊のアニメの話 ・夏は夏でした ・欧州のようにはならないぞ ・みんな脱いでほしいって夕野さんが言ってた ・強めのお薬宛 ・ASMRを聞きながら寝てるんですね ・あのケースにワインを入れたらいいのでは？ ・あの有名な全身筋肉さん ・ぬるぽさんすう教室 ・ﾄｶｼｷｸﾝﾉｺﾀｴ！ ・なんでそんなスピードで走るんですか？ ・マナーの虎宛 ・トウモロコシのマナー ・とんがりコーンは5本の指に入れないと ・じゃあ、コーン茶でいいじゃないか ・ヒゲの有効活用 ・阿佐ヶ谷でヤングコーンのヒゲ ・10月の阿佐ヶ谷の情報ポローン ・しょうゆが活きるメニュー ＜Bパート＞ ・漫才やりますか ・ありがとうございましたーはハモりたい ・写真集で水着解禁しようよ ・2ヶ月近く経っちゃったら賞味期限が切れちゃうだろ！！！！！！ ・ブーメランパンツだと片玉ってわかっちゃうんですかね？ ・ドネシア ・「円安エグッ」って2回言っちゃった ・駿河屋も買い取ってくれないだろ！ ・しまむらより安いじゃないか！ ・VRのハワイならタダ ・VR元年来なかったねー ・みつをたです ・ヤニねこなのに禁煙の役に立つ ・ふしだらな母たちのグッズ ・何も不祥事起こしてないけど坊主にしようかな ・反面教師は大事 ・創作昔話　ごんぎつね ・ごんぎつねフォロワー増えましたね ・一攫千金の願いが健康第一に変わりました ・古いゲームのデータ破損 ・TVerでは削除済み ・にじさんじピックアップニュース ・葛葉とアンジュ名前が似てるからな ・腰の位置は重なってないから大丈夫 ・旦那にはギリギリ聞かれてなかったから大丈夫 ・作詞家だから歌詞が気になっちゃうね ・ホントだセンシティブな歌詞だ ・ホロピックアップニュース ・米食いにハリウッドへ ・ケツバットでバットが壊れる ・素麺の茹で方で笑いがとれる ・すいせいさんが始球式？ ・事前登録130万 ・Vピックアップニュース ・一言でやっつけろのコーナー ・スーパースモーキングタイム ・音だけで楽しめるリズム天国 ＜エンディング＞ ・洞爺湖温泉に1泊してきたんですよ ・5回浸かると効果あるね ・周りはみんな外国人 ・花火はやってましたね ・スポンサーは不明 ・みなさんも洞爺湖行ってください ・自動翻訳で全部「こんにちは」になっちゃう

Neurologist Dr. David Perlmutter Explains Brain Inflammation and Alzheimer's Risk Your brain has its own immune system, and when it turns against you, it becomes the hidden driver behind Alzheimer's, Parkinson's, depression, and even long COVID. This episode hands you the science to recognize it early and reverse it. Get Dr. Perlmutter's new book Brain Defenders: https://drperlmutter.com/books/brain-defenders/ Host Dave Asprey sits down with Dr. David Perlmutter, a board-certified neurologist and six-time New York Times bestselling author whose work sits at the intersection of neurology, nutrition, and brain health. He is a Fellow of the American College of Nutrition, serves on its Board of Directors, and sits on the Editorial Board of the Journal of Alzheimer's Disease. His books, including the number one bestseller Grain Brain, span 32 languages and have sold over a million copies, and his upcoming release, Brain Defenders, explores the pivotal role of microglia, the brain's immune cells, in protecting, repairing, and reprogramming the brain for lifelong resilience. Dave and Dr. Perlmutter break down how microglia, the brain's resident immune cells, shift from a supportive state into a destructive one called M1, and why this shift, not amyloid plaque, may be the real driver of Alzheimer's, Parkinson's, and other neurodegenerative conditions. They dig into why the leading amyloid-clearing drugs fail to improve cognition, what a landmark JAMA study revealed about reversing cognitive decline through lifestyle intervention alone, and why a single daily serving of ultra-processed food raised Alzheimer's risk by 13 percent in a 12.7 year study. They also cover new research on GLP-1 drugs and brain inflammation, the surprising role of gum disease and oral bacteria in dementia risk, and why 40 hertz light therapy is emerging as a low-cost tool for clearing brain plaque and calming neuroinflammation. You'll Learn: Why the shift from supportive to destructive brain immune cells may be the true root cause of Alzheimer's and Parkinson's Why leading Alzheimer's drugs fail to improve cognition, and what the original research behind the amyloid hypothesis actually showed How one daily serving of ultra-processed food raises Alzheimer's risk, and what a landmark lifestyle intervention study found instead Whether GLP-1 drugs help or harm brain inflammation, based on new Parkinson's and Alzheimer's trial data How gum disease and oral bacteria are linked to dementia, and simple daily habits that reduce that risk Why 40 hertz light therapy is emerging as a tool to clear brain plaque and calm neuroinflammation How ketones, DHA, and metabolic health protect the brain after head injury Thank you to our sponsors! - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - ZenBud | Dave's Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount. - Pique | Head over to Piquelife.com/Dave to get 20% off your order. That's P-I-Q-U-E life dot com slash DAVE - PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: microglia, brain inflammation, Alzheimer's prevention, Parkinson's disease, amyloid hypothesis, neurodegeneration, GLP-1 drugs, semaglutide, ultra-processed food, gum disease and dementia, oral microbiome, 40 hertz light therapy, ketones, DHA, mitochondria, brain fog, long COVID, David Perlmutter, Brain Defenders, Grain Brain, functional medicine, biohacking, longevity, neuroplasticity Resources: • Get Dr. Perlmutter's New Book Brain Defenders: https://drperlmutter.com/books/brain-defenders/ • Learn More About Dr. Perlmutter's Work At: https://drperlmutter.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:40 – Intro 02:38 – Ultra-Processed Foods 06:34 – Are Carbs Bad? 08:48 – Alcohol & Brain Health 12:28 – Microglia & Inflammation 24:37 – Head Injury & Recovery 29:27 – Oral Bacteria & Dementia 34:08 – GLP-1s & Brain Inflammation 40:20 – 40 Hertz Light Therapy 48:35 – Air Pollution vs. Lead 50:27 – David's Closing Truth See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

00:00 - 6 óra 30:12 - Beindultak az M1-mémek: Mindenki bocsánatot kér a közmédia stílusában 1:00:46 - Hogy vagy Magyar rovat 1:16:14 - Berobbant a bélgáz a tokiói műtőben 1:32:43 - Balázs talált egy megosztó kérdést, ami a stábot is kettéosztotta...

2 - Beindultak az M1-mémek: Mindenki bocsánatot kér a közmédia stílusában by Balázsék

We discuss awards from the Midseason Astra's & Annecy Film Festival + Odyssey first reactions, TIFF first film premieres, the July 4th Box Office downturn and a host of trailers & reviews, including our Top 10 Films of the Year & Top 5 Most Anticipated. HEADLINES: The Odyssey first reactions - 0:55 The 9th Midseason Astra Movie Awards - 4:09 OUR BEST OF THE YEAR THUS FAR & MOST ANTICIPATED LISTS: AlsoMike's Top 10 Best Films of the Year Thus Far - 6:28 Mike1's Top 10 Best Films of the Year Thus Far - 11:00 Our Most Anticipated Films still to come + Tarantino Talk - 13:06 OSCAR NEWS: Chief Oscars Officer resigns - 23:50 TIFF NEWS: Being Heumann, Prima Facie & The Assassins announced - 27:01 ANNECY FILM FESTIVAL NEWS: including the Gatto Teaser & Awards - 29:44 BOX OFFICE UPDATE: Minions & Monsters struggles as July 4th sees a downturn - 36:36 Obsession still progresses well, but did it go to PVOD too soon? - 40:23 The Rest of the Top 13 including AM's Review of Leviticus - 43:28 TRAILER THOUGHTS: Werwulf, our worries & way too early Oscar guesses for Eggers - 47:50 Late Fame & M1's heel turn on one of his favorite filmmakers - 51:16 The Weight, starring Ethan Hawke & Russell Crowe - 55:06 Super Troopers 3 is hopefully better than ST2 - 57:04 Wildwood (Featurette) has us dazzled - 58:42 OUTRO: We try not to jinx what's coming next, but tell you anyway. Then we blabber on another few minutes about how we were efficient during the recording. Plus, we discuss our excitement for Evil Dead Burn, or lack thereof. https://linktr.ee/mikemikeandoscar

ぬるぽ放送局おたより投稿フォーム https://forms.gle/6tbmBzK6wbyavJG47 2026年7月パワープレイ M1. Comeback 作編曲：HiroHiro & Smeets 音楽ジャンル：Happy Hardcore, UK Hardcore サークル：Notebook Records 収録アルバム：YATSUZAKI HARDCORE COLLECTION 17 2026・7・1 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-017 番組時間：85分2秒 出演者：夕野ヨシミ、たくや VOICEVOX:ずんだもん VOICEVOX:四国めたん ---- 2026/7/2に公開録音したものを配信いたします。 ラジオ記事はリスナーのEEチャンピオンさんが書いてくれているので楽してます。 ＜オープニング＞ ・始まる0秒前までスターウォーズの話してましたよ ・半夏生とは ・黄経（こうけい）100度 ・１週間7日もやめちゃう？ ・あれ？休み減ってません？ ・令和の働き方改革やってもらって ・令和の大合併 ・カレーは強すぎる ・この流れでイオシスくんの活動報告は嫌だな ・ロケテストはもう、おわっちゃったんだ ・重大発表は絶対大したことない ・FANBOXのスパムコメントには気を付けてください ・スープカレープランはいかがですか？ ・YouTubeメンバーシップの値段が140円に（新規の方？） ・YouTube IOSYS musicチャンネル 　フルコーラスが聴けるやつ100万再生！ 　MVはワンコーラスなのでフルも聴いてね 　【東方】行列のできるえーりん診療所【IOSYS】 　歌編曲：D.watt 　音編曲：溝口ゆうま(Innocent Key) 　作詞：七条レタス 　ボーカル：3L ・2026/6/27放送・テレビ朝日『題名のない音楽会』にて「みんなの　とまチョップ」が演奏されました！ 　作曲：D.watt(IOSYS) ・THE IDOLM@STER CINDERELLA MASTER NUMBER ONE! 　「ROSE ～禁じられた愛～」 　作詞：夕野ヨシミ 　作編曲：ARM 　歌：桐生つかさ、木村夏樹、白雪千夜 　2026/7/1リリースされました！！ 　MV見てね ・みんなで決めた曲です ・楽器も聴いてもらってもいいですか ・スタッフリストが長い ・毎日聴いてください ・2026/7/5　ヤツコアあります ・2026/10/24のイオシストークライブのリーク情報 ・夕野ヨシミと言えば…バニーガール！ ・しょうゆを仕込んでいます ・しょうゆ生絞りショーご覧いただけます ・トーク醤油ってこと？ ＜Aパート＞ ・ふつおたです ・ラフさんが隣の部屋で別の生放送に出てます ・ペロっ！これは醤油！ ・PS Vita探します ・ゲームもパッケージ版が出なくなる ・steamのライブラリがぐちゃぐちゃに ・ファルダ作れますよ？ ・カッコいいキャラにカッコよく歌わせるトンチキソング ・デレマス総選挙 ・グリーンバック素材なので、ご活用していいんですよね？ ・KMNZの話 ・ちょうどいいまとめ具合 ・500行のおたよりは読めない ・強めのお薬宛のお便り ・あの…お便りありがとうございます ・南平岸には、いったい何が ・パワープレイの間にピザ画像を送ってもらって ＜Bパート＞ ・UKハードコア ・UKなのにアメリカの曲？ ・困ったらダンス＆ハウス ・プラン名言っちゃった ・みつをたです ・直射日光を舐めたらいけない ・ハンディファンはあった方がいいですよ ・うちの猫のにゃーんが入っちゃった ・センチメンタルグラフティのオーディションに声優29歳の壁 ・なんでもありの餓狼伝説 ・ごんぎつねリベンジ ・しわくちゃゴールデンボール ・審神者みつを ・いったん暗転してるんだけど ・もうちょっとダジャレ感が出ると創作昔話ごんぎつね感が出ます ・ごんぎつねワールドカップ ・折り返し好きだからね ・創作昔話　ごんぎつね ・あーあーあーひどい ・5時に起こして ・日本対ブラジルいい試合でしたよ ・キャプ翼の頃からブラジルは強い ・もう、ワールドカップの話したくなったよね ・身の振りようがねーな ・にじさんじピックアップニュース ・るんちょま活動休止 ・今週一番ショックを受けてます ・その間イオシスが、がんばります！ ・自認江渡貝くん ・にじさんじ甲子園始まる ・水風呂で生活したい ・みんなパワプロ好きだね ・ホロピックアップニュース ・なんで7台も掃除機を？ ・画鋲でも敷けばいいのに ・しゃべる陰キャ ・Vピックアップニュース ・NIKKEにVTuberが？ ・一言でやっつけろ ・世の中楽しいことがいっぱいあるね　みつを ・インチャネ懐かしいですね ＜エンディング＞ ・あっちのイオシスさんの話 ・安心してください履いてませんよ ・何もないですか？ ・ためるような話ではない ・スープカレープランの名称がピザプランに変わります ・写真はぼいどさんです ・何で縦横比が違うのか

The UK Midlands is a region steeped in history and folklore, from the ancient Kingdom of Mercia to the birthplace of Shakespeare. But on a freezing, misty day in December 1993, a peaceful village right off the M1 motorway became the backdrop for a living nightmare. While driving past a dirty station wagon parked on a grassy verge near Junction 20, a local witness noticed a passenger sitting bolt upright in the backseat wearing a jet-black dress. It was a sight that made her blood run cold; she knew with absolute certainty that the woman was already dead. What followed was a massive police hunt for a transient predator who used England's motorways to hide in plain sight, Alun Kyte, the Midlands Ripper. Join Jen and Cam as they discuss 'Monster on the M1: The Murders of Samo Paull & Tracey Turner.' Our team: Listener Discretion by ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Edward October ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Research & Writing by Lauretta Allen Executive Producers Nico & Jesse of ⁠⁠⁠⁠The Inky Pawprint⁠ Sources: https://www.youtube.com/watch?v=E7_M0eU6pVk&t=7s https://www.youtube.com/watch?v=g1hGFRvWqyo https://en.wikipedia.org/wiki/Alun_Kyte https://www.bbc.com/news/uk-england-south-yorkshire-48254878 https://crimeimmemorial.com/2024/09/15/yvonne-coley/ https://murderpedia.org/male.K/k/kyte-alun.htm https://www.the-independent.com/news/uk/crime/janine-downes-death-police-appeal-b1796190.html https://crimeimmemorial.com/2024/10/15/gail-whitehouse/ https://www.bbc.com/news/uk-england-shropshire-12297341 https://www.westmercia.police.uk/news/west-mercia/news/2021/february/detectives-continue-to-appeal-for-information-into-womans-murder-on-30th-anniversary/ https://www.walesonline.co.uk/news/uk-news/unsolved-murder-revisited-after-34-31844795 https://www.coventrytelegraph.net/news/local-news/missing-coventry-sex-workers-victims-22984273 https://lolly-truecrime.medium.com/natalie-pearman-was-16-years-old-when-her-body-was-found-in-a-lay-by-on-ringland-road-norwich-8ba882b288ca https://www.thetimes.com/uk/law/article/child-abusing-double-killer-suspected-of-other-murders-7t2pjsm73 https://www.bbc.com/news/uk-england-stoke-staffordshire-65556070 https://music.amazon.com/podcasts/ac7a330a-afe6-4247-a106-10e59fba8651/episodes/7e1fe6a3-895f-452d-9512-b307a319fbb5/they-walk-among-us---uk-true-crime-midlands-ripper-alun-kyte---part-1 (and also part 2)https://www.newspapers.com/image/719963897/? match=1&terms=Alun%20Kyte https://www.newspapers.com/image/259073041/?match=2&terms=Alun%20Kyte https://www.newspapers.com/image/867605363/?match=2&terms=Alun%20Kyte https://www.newspapers.com/image/808440223/?match=1&terms=Alun%20Kyte https://www.newspapers.com/image/822427249/?article=a4f38430-aabb-4708-a3fb-f982c5af9186&terms=Alun%20Kyte https://www.newspapers.com/image/822427249/?article=a4f38430-aabb-4708-a3fb-f982c5af9186&terms=Alun%20Kyte https://www.newspapers.com/image/719023877/?match=1&terms=Samo%20Paull https://en.wikipedia.org/wiki/Balsall_Heath https://www.newspapers.com/image/866507468/?match=8&terms=Samo%20Paull https://www.newspapers.com/image/865864192/?match=1&terms=Samo%20Paull https://www.newspapers.com/image/865864423/?match=6&terms=Samo%20Paull https://grokipedia.com/page/Alun_Kyte#:~:text=The%201994%20Murders,December%201993.%20%5B9%5D%20Her%20body https://www.newspapers.com/image/878164808/?article=3ed5a862-86a9-47e0-9de9-0bfce9a53075&terms=%22Tracey%20Turner%22 https://en.wikipedia.org/wiki/Murdered_sex_workers_in_the_United_Kingdom   Learn more about your ad choices. Visit megaphone.fm/adchoices

In today's episode, we'll be talking about the connections between Fiona, the marionette, and M1. We'll also talk about the Into the Pit Victims, Garten of Banban, and poppy playtime!------------------------------------------------------------------------------------------Check out my patreon for priority questions on this podcast, early and adfree versions of videos, and more!https://www.patreon.com/c/RyeToastYT----------------------------------------------------------------------------------------To submit questions, theories, and creator collab requests, email at: FreddyFazbearPizzaPodcast@gmail.com --------------------------------------------------------------------------------------------------Don't forget to use code RYETOAST for 10% off your whole order! https://gamersupps.gg/ryetoast----------------------------------------------------------------------------------------Intro/Outro music by: @Miri789 Thumbnail template by BarBADroid!https://barbadroid.carrd.coFreddy Fazbear Pizza Podcast is YOUR premiere FNAF podcast available everywhere!Youtube: https://youtube.com/playlist?list=PLlGAFKgA2Ax_6MKnuaq5ApBgC8osKW4Dx&si=jB2ja5c4k_OnCZQQSpotify: https://open.spotify.com/show/1a65iwRRAQylxb9EtRWmsdApple Music: https://podcasts.apple.com/us/podcast/freddy-fazbear-pizza-podcast/id1705899138Amazon Music: https://music.amazon.com/podcasts/4c77d1d8-077d-463d-b48e-21280279e281/freddy-fazbear-pizza-podcast--------------------------------------------------------------------------------------------------Wanna get me something? https://throne.com/ryetoastHere are all my socials and ways to support the channel!https://ryetoast.carrd.coJoin our growing community on discord! https://discord.gg/azPjrGGdBY----------------------------------------------------------------------------------------------------------------------Some renders in thumbnail created by Spencer Singer https://linktr.ee/mlspence3d-----------------------------------------------------------------------------------------------------------------------For Brand Deals and Sponsorships, contact: ryetoast@apollomgmt.co

Detroit didn't just build cars. During World War II it built the machine that helped win the war. In the final installment of our three-part series on American manufacturing history — marking the 250th anniversary of the United States — AAM President Scott Paul visits the Detroit Historical Museum to walk through the story of the “Arsenal of Democracy” with the Detroit Historical Society's Director of Collections, Jeremy Dimick. They trace how the Motor City's auto plants pivoted to produce a B24 bomber every hour and more than 90% of America's M1 helmets, and how that effort remade the city of Detroit.

Broadcast from KSQD, Santa Cruz on 6-25-2026: Dr. Dawn devotes the show's opening to ivermectin for COVID. She walks through critical thinking principles—considering the source, cross-verification, and recognizing self-interested claims—before reviewing the evidence. The most-cited 2021 Bulgarian study of 300 people showing 77% reduction lacked accessible methods, and larger trials capable of detecting even small benefits failed to confirm efficacy. On safety, the standard 12mg parasitic dose every few weeks is well-tolerated due to the blood-brain barrier and efflux pumps that keep ivermectin out of the brain, but daily long-term dosing has caused encephalopathy, liver and kidney damage, and birth defects. Critical drug interactions—macrolide antibiotics, verapamil, proton pump inhibitors, and beta blockers—disable the efflux mechanism, and high-fat meals increase absorption 2.5-fold. Dr. Dawn shares two inflammation formulas calculable from any CBC. The Systemic Inflammatory Index (neutrophils × platelets ÷ lymphocytes) flags runaway inflammation: 200-500 is good, above 900 warrants investigation and correlates with worse stroke outcomes and rising tumor burden. The SIRI (neutrophils x monocytes ÷ lymphocytes) detects chronic tissue inflammation and early innate immune activation: below 500 is good, above 1500 indicates trouble and correlates with cardiovascular mortality and arterial plaque from M1 macrophage activity. Dr. Dawn shares two takeaways from the Institute for Functional Medicine annual conference: in patients at high cardiovascular risk by cholesterol, each gram daily of combined EPA/DHA produces a 9% risk reduction, with bruising as the dose-limit signal. Additionally, a 15-minute walk within 30 minutes of a meal nearly eliminates postprandial inflammation. An emailer asks whether an endocrinologist's claim that vitamin D leaches calcium from bones is true. Dr. Dawn confirms that very high vitamin D (above 150 nanograms, with concern starting above 90) elevates 1,25-vitamin D, which stimulates osteoclast formation and increases C-telopeptide markers of bone breakdown. A crowdsourced question asks how histamines work in women. Dr. Dawn explains histamine functions as a CNS neurotransmitter promoting alertness, wakefulness, and pain perception (deficient in narcolepsy), and as a GI signal driving acid secretion, motility, and visceral sensation. Gut bacteria can convert histidine to histamine, and fish left to spoil can trigger anaphylactic-like reactions from accumulated bacterial histamine. She notes stomach acid treatments Tagamet and Zantac are H2 blockers rather than the more familiar H1 antihistamines, and confirms histamine correlates with hormones but not particularly with minerals. A crowdsourced question on B vitamins for women in their mid-twenties prompts Dr. Dawn to recommend prenatal vitamins for those who might become pregnant, and B100 complex with calcium taken with a little apple cider vinegar for those on restricted diets or eating mostly fast food. Another question asks about chest versus belly breathing. Dr. Dawn explains babies demonstrate proper diaphragmatic breathing (belly protrudes on inhalation) while accessory muscle use signals fight-or-flight—or pneumonia in a non-crying infant. Chest breathing raises adrenaline; belly breathing calms it in adults. How do I stop compulsive scratching? Dr. Dawn explains neurodermatitis has its own ICD-10 code alongside compulsive nail-biting and hair-pulling, and it is diagnosed by sparing of unreachable areas like the mid-back between shoulder blades. Treatment includes nail clipping, lubricants, covering scabbed areas, and Prozac—which uniquely among antidepressants has a secondary indication for neurodermatitis. Zurich researchers combined immature human nerve cells with magnetic nanoparticles to create 6-micrometer NPC bots that can be magnetically positioned at spinal cord injury sites and then triggered by pulsatile magnetic stimulation to mature into nerve tissue. Mice with severed spinal cords regained movement and brain-muscle electrical signals by day 34 after daily 30-minute treatments. A study of 15,000 people with myalgic encephalomyelitis/chronic fatigue syndrome identified eight genetic regions distinguishing them from controls. Two relate to immune response to infection—consistent with the post-infectious onset many sufferers describe, including roughly half of long COVID patients—and others link to the nervous system and chronic pain. Dr. Dawn frames ME-CFS as an immune system stuck in the "on" position, unable to brake against an enemy that is long gone. An emailer asks about prostate biopsy approaches. Dr. Dawn explains the new transperineal biopsy (through skin between scrotum and anus) reduces post-biopsy infection from 1.5% to near zero and eliminates prophylactic antibiotics, though it requires more anesthesia and time. Cancer detection rates match the transrectal approach when both use MRI targeting, and she expects the transperineal approach to become standard.

小時候跌倒長輩說「痛痛飛走了」 你有沒有覺得，好像真的沒那麼痛了？ 那些我們小時候看似荒唐的安慰動作 原來不是單純的心理作用 背後隱藏一個非常真實的生理反應在發生 是一集整理完資料後會讓一些鐵齒人三觀大改的主題 讓安慰不只是嘴上說說而已 而是真實發生在你體內的事 你也有哪些小時候到現在都還是會做的安慰動作嗎 也來社群分享經驗給我們吧！ -------------------------------------------- ⚡哈拉充能量 × 豐傑生醫 限時優惠⚡

New Academy Member: Jacob Elordi - can M1 deal with this? Then we discuss Venice Film Festival rumors and another Obsession centric Box Office Report before we dive into reviews for Supergirl, Voicemails for Isabelle and a bunch of other films old & new. And if that's not enough, you get a Trailer Thoughts segment with our thoughts on ALL of the new trailers. NEWS: New Academy Members Invited including Elordi, so we discuss 007 casting - 1:20 The Knicks are Champions / Life of Pi Metaphor - 7:15 The Venice Film Festival selects its Jury President, Maggie Gyllenhaal - 8:32 Venice Film Festival Rumors including known and unknown (to us) contenders - 10:43 Anything Emmy's? Sure. We hint at our favorite races incoming + Doc thoughts - 24:37 BOX OFFICE REPORT: Toy Story 5's second week - 28:14 We remain Obsession Obsessed - 28:58 A word on the early buzz for The Invite - 36:02 Supergirl's Flop & AlsoMike's Review - 37:44 MORE WHAT WE'RE WATCHING: Voicemails From Isabelle was great. WTF - 48:19 M1's regularly scheduled watching of previous noms: The Grifters & Prizzi's Honor - 54:02 M2's regularly scheduled addiction to new films: Power Ballad, Pressure, I Love Boosters, The Furious, Nirvana The Band The Show The Movie & Scary Movie - 58:15 TRAILER REVIEWS: Digger (Teaser 2): The Tom Cruise Oscars Campaign Has Begun - 1:08:45 The Debut: Which Mike liked Magnolia and which did not REVEALED! - 1:14:37 Sense & Sensibility: The Finest Fee Fee Film of our Time - 1:20:08 I Want Your Sex: Olivia Wilde's statement film - 1:22:42 Spider-Man: Brand New Day: Just release it. We're ready - 1:25:28 Rapid Fire Takes for Primetime, Whalefall, Klara and the Sun, Shrek 5 & Hexed - 1:27:17 OUTRO: stay tuned to our feed for upcoming Oscar Race Checkpoints on the Fall Film Festival Lineup announcements amidst all our coverage of the rest of this big movie summer we're about to start. Plus, did we just come up with the name for our Inarritu Rewatch Series??? https://linktr.ee/mikemikeandoscar #mmo

本集節目由【豐傑生醫】贊助播出 你有發現記憶深刻的事情通常是壞事情嗎? 為什麼別人稱讚你五分鐘就忘了 但有人嗆你一句卻能記一輩子? 這集聊的是一件你一定有感覺 卻很少停下來想的事 我們打開新聞、滑開社群 排在最前面討論最熱烈的幾乎都是壞消息 其實不是這個世界突然變壞了 而是我們的大腦天生就是一台「壞消息雷達」 如果你最近覺得社會好亂心情總被新聞牽著走 那這集很適合你來解惑我們的大腦是如何運作的 你會更懂自己為什麼會這樣 也會聊聊要如何與壞消息和平共處 開頭的「哈拉新體驗」 聊聊五月中開通的淡江大橋 從一開始發想到卡關一直聊到完工 過程中發生了哪些有趣的故事 可以讓你下次經過淡江大橋時 會對這座橋有更多的感受與體驗 一起來了解這座創下世界紀錄的淡江大橋吧！ -------------------------------------------- ⚡哈拉充能量 × 豐傑生醫 限時優惠⚡

On this week's episode of The MacRumors Show, we continue unpacking WWDC 2026 and take a closer look at iOS 27, macOS Golden Gate, and Apple's other new software updates coming this fall.00:00 — Intro & beta check-in00:42 — OS compatibility cuts: watchOS, iOS, macOS, tvOS, iPadOS09:49 — Sponsor: Claude11:08 — Liquid Glass refinements & redesigned icons14:10 — Shortcuts with natural language16:34 — Sidebar icons, extra-large widgets & foldable iPhone hints18:43 — Siri's new design & dynamic island shape20:20 — Siri AI in practice: autocorrect, clarifications, and daily use25:57 — Third-party AI extensions & region availability30:03 — Apple Intelligence across apps: Messages, Image Playground, Genmoji, Passwords, nutrition39:35 — macOS Golden Gate & the keynote's new format44:39 — iPadOS, watchOS, visionOS, tvOS, and HomeKit hintsiOS 27 supports the same iPhones as iOS 26, including the iPhone 11 and second-generation iPhone SE, giving the update the widest device compatibility of any iOS release to date.macOS Golden Gate drops Intel Macs entirely, confirming the end of an era that Apple flagged a year earlier when it said macOS Tahoe would be the final release for pre-Apple silicon machines. Four models that ran Tahoe miss out: the 16-inch MacBook Pro (2019), the 13-inch ‌MacBook Pro‌ with four Thunderbolt 3 ports (2020), the 2020 iMac, and the 2019 Mac Pro. Golden Gate is also the last version with full Rosetta 2 support, meaning the translation layer that keeps Intel-built apps running on Apple silicon will disappear entirely after this release.iPadOS 27 raises its hardware floor to the A14 Bionic or M1 chip, cutting the fifth-generation iPad mini, the eighth-generation iPad, the third-generation iPad Air, the first-generation 11-inch iPad Pro, and the third-generation 12.9-inch ‌iPad Pro‌.watchOS 27 makes the steepest cuts in Apple Watch history, dropping the Series 6, Series 7, Series 8, original Ultra, and second-generation SE in a single wave and effectively erasing three years of device support at once. The only models that remain compatible are the Series 9, Series 10, Series 11, Ultra 2, Ultra 3, and SE 3.tvOS 27 drops two Apple TV models, the Apple TV HD from 2015 and the first-generation ‌Apple TV‌ 4K from 2017, leaving only the second- and third-generation ‌Apple TV‌ 4K boxes supported.In ‌iOS 27‌, notifications now slide in from the left edge of the screen rather than dropping down from the top, and reaching Notification Centre requires swiping down from the top-left corner instead of the centre, freeing up that gesture for Siri. Other changes include colorful sidebar icons, real-time widget updates when an app is already open, extra-large Home Screen widgets, and web audio that no longer interrupts other system audio.The centerpiece of the update is Siri AI, which replaces Spotlight with a "Search or Ask" interface accessed by swiping down from the center of the display. ‌Siri‌ is designed to tone-match a user's own writing style when composing messages. Apple's pill-shaped ‌Siri‌ indicator is seemingly a hardware workaround for current Dynamic Island constraints, and a smaller ‌Dynamic Island‌ on the iPhone 18 Pro could allow the indicator to become a true circle. On the Apple Watch, ‌Siri‌ AI requires pairing with an iPhone that supports Apple Intelligence. In the European Union, ‌Siri‌ AI is available on macOS and visionOS at launch but not on the iPhone or ‌iPad‌.‌Apple Intelligence‌ is also getting smarter Writing Tools and a composition assistant in Mail and Messages that adapts to how a user typically communicates with different contacts. Apple has overhauled Genmoji, adding a "Describe a change" interface for iterating on existing creations and the ability to start a new Genmoji from an existing emoji, a photo, or a person tagged in the user's photo library. Image Playground similarly adds support for multiple aspect ratios for wallpapers, Contact Posters, and social media images, alongside new photorealistic image generation.Visual Intelligence, meanwhile, gets a new primary entry point called ‌Siri‌ Mode, though holding down Camera Control still works as an alternative. The feature is expanding to the ‌iPad‌ and Mac, and now supports importing multiple calendar events from a single photo of a flyer, as well as importing contacts directly from a photographed business card.On the Mac, ‌macOS Golden Gate‌ extends toolbars and sidebars to the edges of the screen with a more consistent, tighter corner radius across windows. iPadOS 27 adds undo and redo for ‌Home Screen‌ edits, extra-large widgets in Today View, an optional persistent menu bar, and Visual Intelligence support for screenshots combined with Apple Pencil highlighting. Notes gains an Image Wand tool that generates photorealistic images from rough sketches, the ‌Siri‌ app gets a dedicated sidebar with full windowing support, and Shortcuts adds support for Magic Keyboard triggers.watchOS 27 drops the Walkie-Talkie app entirely, with the feature missing from both the app list and Control Center in the first developer beta, while adding new Smart Stack suggestions, more accurate step tracking, and a consolidated Find My app. visionOS 27 lets users activate ‌Siri‌ simply by looking at its on-screen bubble rather than requiring a button press, and adds a redesigned Control Center along with new curved windows. tvOS 27 brings a redesigned Podcasts app, Hi-Res Lossless audio support in Apple Music, and on-device processing for HomeKit Secure Video.Ready to tackle bigger problems? Get started with Claude today at — https://www.Claude.ai/mac

Knicks superfan Timothee Chalamet referenced his Oscars loss in a viral moment after NY's championship win. Will it hurt his chances? Glenn Close, Floyd Norman and Ridley Scott will receive Honorary Oscars at the Governors Awards. Plus, we have Tribeca Stories, Academy Initiatives, Box Office Reports & Contender Trailers all to discussion on this overdue episode of Oscar Race Checkpoint. THE KNICKS ARE THE 2025-26 NBA CHAMPIONS: Top of the Show But does Timothee's viral moment haunt him? - 3:48 AWARD NEWS: Governors Awards Picks are in - Glenn Close, Floyd Norman & Ridley Scott - 11:52 Disclosure Day & Obsession Box Office could raise their Oscars Chances - 21:21 AMPAS to launch list of 50 Exceptional Indie Theaters after the 99th - 34:44 Elon Musk slams The Odyssey's casting choices - 39:47 WHAT WE'RE WATCHING: Also Mike's Tribeca Festival Stories: Win Son Bakery + Doc Meets World - 45:31 Clean Hands w/ a special appearance by Robert De Niro - 49:33 The Lions Bar + In Memoriam starring Marc Maron, Lily Gladstone etc - 54:16 Mike1 Recommendations: M1 shouts out The Tony's - 59:25 M1 reviews Nirvana the band the show the movie - 1:00:16 M1 reviews Omaha starring John Magaro - 1:02:06 CONTENDER TRAILERS: The Social Reckoning seems like appointment viewing, but politically pointed - 1:04:54 Wildwood looks like an Animated Feature frontrunner - 1:07:32 Heart of the Beast could be much more of a contender than we first thought - 1:08:52 How To Rob A Bank makes us rethink our September biases - 1:10:32 OUTRO: Thanks to Jalen Brunson, Leon Rose, Mike Brown and everybody at the New York Knicks for giving AlsoMike the greatest weekend of his life. Thanks to all of our listeners who allowed us to spin this into an Oscars story. And thanks to everybody at the Academy and the Tribeca Film Festival, etc… for giving us more than enough movie topics to discuss in addition to AM's Knicks miracle. Thank you! The Knicks are the champions! The Knicks are the Champions of the basketball world!!! https://linktr.ee/mikemikeandoscar

Noctis ft M1 on Sub FM 7th June 2026 - https://www.sub.fm

We study Steven Spielberg's E.T. - The Extra Terrestrial for our MMO UFO (mini) series leading up to Disclosure Day. NON-SPOILER REVIEW - 4:53 M1's 1st Watch Memory & Does it live up to our childhoods? - 7:07 Development Backstory - 10:07 Reception: Box Office, Critical, Audience, Oscars Profile, etc - 14:59 Tremendous Child Actors Made This Movie Work - 17:25 Little Green Men & Men In Black Tropes - 22:04 Other Performance Reviews including the voice of E.T. - 28:41 Production Values featuring the illustrious John Williams - 32:50 SPOILER FILLED REVIEW: 36:50 Bad Friends, but Relatable Families - 38:05 Adorable Meet Cutes, Language Barriers & Frogs - 48:56 Peter Pan Storytime & Halloween is a rough day for mom - 57:07 Gripes - 1:01:39 That Glorious Ending - 1:07:18 OUTRO: We continue to discuss our expectations for Disclosure Day. So yes, make sure to stay tuned to our feed for upcoming episodes on Disclosure Day, the Tribeca Film Festival, The Rock, Toy Story 5, Supergirl, Summer Oscar Bets, The Odyssey etc… etc..

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

DeepSeek V4 casse les prix des grands modèles IA, Nvidia prépare des PC Windows façon “moment M1”, BYD remplace Nvidia par ses propres puces pour ses voitures électriques, et des robots ménagers sont entraînés chez les particuliers contre du ménage gratuit. Films entièrement générés par IA, lip-sync artificiel au montage, SSD capable de trahir vos usages, âge vérifié sur Linux, extraction du lithium et pollinisateurs détectés par machine learning complètent cette revue Tech & IA.  Me soutenir sur Patreon Me retrouver sur YouTube On discute ensemble sur Discord Modèles de la semaine ASASR (creed?), le bruit prend des couleurs. Controllight, collection Lora et NeuROK, MAI-Image 2.5, le meilleur modèle de la semaine pour la pub. Deepseek V4 coûte rien, comment font ils ? Encore un long métrage IA ? Quelle bonne vanne. Après la Google I/O, DuckDuckGo va-t-il exploser ? Comme Bluesky ? Souriez, vous êtes nettoyés ! Chaud et Froid NVIDIA nous promet une révolution inTEGRAle du PC ! Comme en 2012 ! BYD ne veut plus de NVIDIA, à Thor ou à raison. C'est chaud : Intel revient dans l'IA et des barettes de ram avec des ventilateurs. Legend of the FROST : espionné par son SSD… Et maintenant, des radars à mouches. Des batteries toujours moins chères. Plus de contrôle de l'âge sous Linux. Du coup c'est avec ou sans porno ? Participants Une émission préparée par Guillaume Poggiaspalla Présenté par Guillaume Vendé

It's developer conference season, and one of the themes so far has been big swings at AI apps. We've seen Gemini Spark, Microsoft Scout, and so many other attempts to figure out what people, and companies, actually want their AI to do. Nilay and David discuss their experiences with the apps, before turning to Nvidia CEO Jensen Huang's vision for the AI-filled laptop of the future. Finally, in the lightning round, it's time for the Hype Desk, Brendan Carr is a Dummy, a deeply dumb Meta hack, and the future of a favorite VR game. Further reading: ⁠Testing Google's Gemini Spark AI agent: it's incredible, and creepy ⁠ ⁠Gemini's new AI agent is about as good as Google's demo ⁠ ⁠Microsoft Scout is a new AI personal assistant built on OpenClaw ⁠ ⁠Microsoft's Project Solara is an OS for AI agent gadgets ⁠ ⁠As AI gets better, it reveals an empty promise ⁠ ⁠Let us filter AI slop, you cowards⁠ ⁠Microsoft and OpenAI broke up — now they're ready to fight ⁠ ⁠These are the first Nvidia RTX Spark laptops ⁠ ⁠This is the Microsoft Surface Laptop Ultra with Nvidia RTX Spark ⁠ ⁠A first look at Microsoft's Surface Laptop Ultra and Surface Dev Box⁠⁠ ⁠ ⁠Nvidia is already planning N2X and N3X chips — the goal is the Star Trek computer ⁠ ⁠This could be Windows' M1 moment — but expect it to cost a ton ⁠ ⁠Computex 2026: All the news and announcements ⁠ ⁠Meta's own AI was exploited to hijack Instagram accounts⁠ ⁠Apple's strategy for smart glasses is the same as for smart watches ⁠ ⁠It sure seems like the Vision Pro isn't getting upgraded for a while — if ever.⁠ Subscribe to The Verge for unlimited access to theverge.com, subscriber-exclusive newsletters, and our ad-free podcast feed.We love hearing from you! Email your questions and thoughts to vergecast@theverge.com or call us at 866-VERGE11. (Timestamps are approximate.) 00:01:00 Intro 00:03:00 New Verge Merch Drop 00:09:00 Gemini Spark Test Drive 00:13:00 Privacy Tradeoffs Debate 00:21:00 Software Brain Pushback 00:36:00 Jensen Huang Computer Future 00:39:00 Microsoft Build Reality Check 00:41:00 Nvidia Spark Recall 00:42:00 Microsoft Badge Agents 00:54:00 Escaping Apple Tax 00:57:00 Wearables Walled Gardens 01:05:00 Hype Desk 01:06:00 Bond Game Streaming 01:09:00 Summer Games Fest 01:11:00 State of Play Highlights 01:11:00 God of War 01:14:00 Wolverine Gore Talk 01:15:00 Widows Bay 01:17:00 Lightning Round 01:17:00 Brendan Carr is a Dummy 01:26:00 Apple Glasses Rumors 01:36:00 Privacy Backlash Risk 01:38:00 Meta AI Hack Fiasco 01:43:00 Supernatural Returns 01:47:00 Wrap and Next Week Learn more about your ad choices. Visit podcastchoices.com/adchoices

In the final episode of the 2026 Boot Camp series, Paul Merriman sits down with Chris Pedersen and Daryl Bahls to tackle the last fork in the road every investor faces: how to and how much automation to use. After all the boot camp decisions — stocks versus bonds, which equity asset classes, how much fixed income, how to handle contributions and withdrawals — the final question is how much of the day-to-day management you should hand off to a tool, and which tool is right for you.Chris walks through how M1 Finance “pies” let buy-and-hold investors put their portfolios on autopilot: automated contributions, on-the-fly rebalancing as new money comes in, fractional shares, and one-button rebalancing. He explains the pre-configured Merriman portfolios — the Ultimate Buy and Hold, Worldwide and US Four-Fund, All Value, All Small Cap Value, and the Aggressive Target Date glide path in five-year increments — and an important limitation: once you grab a pie, there’s no live link back to the source, so website updates won’t change your account.Paul then makes the case for Fidelity’s Basket Portfolios as an alternative, especially for anyone uneasy about moving large sums to a younger company. He covers the flat $4.99-per-month fee regardless of account size, eligible account types, the TFLO short-term Treasury workaround for holding cash, and why Fidelity may fit investors already in the Fidelity ecosystem. The team compares trading windows, account minimums and how each firm counts the $10,000 threshold, and Daryl shares that M1 has grown from about $1 billion in 2020 to roughly $12.5 billion in assets under management.The conversation closes with practical guidance on mixing and matching Sound Investing portfolios, the question everyone’s asking — “how long do I have to wait for small cap value?” — a reminder not to flail or chase recent performance, why the 10-fund Ultimate Buy and Hold strategy still stands, and a clear explanation of the move from AVUS to AVLC and where AVSC fits.CHAPTERS00:00 - Intro03:10 - M1 Finance13:45 - Fidelity Baskets24:27 - Portfolio Combos29:55 - When to Change Allocations42:44 - AVLC vs. AVUS45:15 - OutroLINKS:Sound Investing Portfolio PiesM1 Finance Pie Tutorial (Mobile App)M1 Finance Pie Tutorial (Web Interface)

https://youtu.be/sUyjA0muVgM Tom Kirkham, Founder and CEO of Kirkham IronTech, believes business should create value for everyone involved — employees, clients, vendors, and the broader community. After overcoming major personal challenges and rebuilding his perspective on leadership, Tom embraced stakeholder capitalism and built a company culture focused on long-term partnerships, trust, and continuous learning. In this conversation, Tom shares the IronTech Framework — a practical approach to modern IT management built around three core pillars: Generate ROI and Productivity, Make Cybersecurity Core, and Surround it with a Governance Layer. He explains why businesses should stop treating IT as an expense and instead view it as a strategic investment that improves productivity, protects the company from cyber threats, and aligns technology with leadership goals. Tom also dives into the massive scale of the cybercrime industry, why governance is often the missing piece in cybersecurity, and how proactive IT strategy can dramatically improve business performance. — Turn Your IT into Your Growth Engine with Tom Kirkham Good day. Steve Preda here with the Management Blueprint Podcast, and today’s guest is Tom Kirkham, the Founder and CEO of Kirkham IronTech, where he helps businesses build strong, secure IT foundations, whether fully managed, co-managed, or cybersecurity only. Tom is a keynote speaker on cybersecurity, and he’s the author of two books, Hack the Rich and The Cyber Pandemic. Tom, welcome to the show.  Oh, it’s great to be here, Steve.  Well, great to have you here. And I am curious to dive in, and would like to ask you my favorite question. What is your personal ‘Why’, and how are you manifesting it in Kirkham IronTech?  That’s a great question. So the company’s about twenty-six years old. I went through a lot of personal health problems, and then my wife was real sick, and she ended up passing away—it's been about eleven years ago now. And I was fortunate enough to put a friend of mine in the company, and he was able to take over while I was dealing with this for a couple of years. And when most of it was done, I took some time off and did a lot of traveling and a lot of thinking and a lot of reading. And I’m a lifelong reader, a lifelong learner, and I went back through my history of investing techniques, understanding what makes a good company great. If you’ve read Jim Collins, you know what I’m talking about. And so during those times, I was reflecting, studying philosophy, studying biographies of other CEOs like Elon Musk, Steve Jobs, Andy Grove—gosh, the list goes on and on. Whether you like them or hate them, it doesn’t matter, right? There’s always something you can learn. And I came upon and read a lot about stakeholder capitalism. Like Peter Drucker says, “Culture eats strategy for breakfast.” And I understood what that meant, and it was kind of weird. So when I re-engaged with the company, I identified one of the weaknesses, and I said, “Well, if we need to do marketing in this business—which we have to do in any business—I really need to master marketing.” So I spent a lot of time with marketing gurus, most of them are what I would consider household names these days, and re-engaged with the company to do marketing to establish a great culture around stakeholder capitalism. In other words, we exist as a for-profit business not just for the shareholders but for everyone—the community, vendors, employees. And I really wanted to be around people I enjoyed being around. I wanted them to enjoy coming into work.Share on X And so we’ve been trying to perfect that system in the culture for the past ten years. Of course, no one's perfect, but if you pursue perfection, you can achieve excellence. And I think we've done a really good job. We have very low turnover. Everyone seems genuinely happy to be there, and it's really fulfilling. It's more of a personal feeling because I've been a successful investor practically my whole adult life. I started investing in stocks when I was nineteen, and I'm sixty-four now. So I didn't really need the company. I could have just closed it up or sold it or whatever. But I really wanted to have my own reasons. Those are the things that drive me, and I hope they drive everyone else too.  What resonated with you with this idea of stakeholder capitalism? It just made sense. The obvious part is with employees—all of that is true. That's obvious to any good leader or manager, right? As you well know, there's a difference between leadership and management, and understanding that distinction, and the difference between sales and marketing, and understanding those things. A good example is dealing with vendors. There are all sorts of vendors that supply products and services to us, so we carefully vet these tools and vendors to see if their values align with ours, just like we do with prospects. But especially with vendors, if it's something new—a new tool that we're going to invest a lot of time, money, and energy into to make their product or service successful for us and successful for them—we make a commitment to that vendor.  So it's not about the money or how cheap I can get it. What I want is a good partnership with every stakeholder. And I want to make sure that when I'm dealing with a vendor, if it fails for us, it's not our fault—it's their fault, right? Either they oversold the product or they didn't deliver on the service component. I didn't want it to be because we failed to do the right training, or didn't communicate properly, or missed all the other things that are just part of doing business the right way. And that applies to our employees, our local community, and every stakeholder in the company.  Yeah. I like it. So you're looking for partnership-based relationships where it's win-win. And yeah, if you want people to stick around, it has to make sense for them too. You can't exploit your partners forever without consequences. So that makes a lot of sense. So Tom, let me ask you this other question. This podcast is called The Management Blueprint because I'm always looking for frameworks—something practical that helps businesses achieve results. Usually it's some kind of three-to-five-step process that helps you grow the business, get customers, improve operations, or understand something at a deeper level. So when I ask about your favorite business framework, what comes to mind?  Well, we have a thing we call the IronTech Framework.  Okay.  And it was something that we came up with many years ago and started practicing seven or eight years ago, and it's a framework. It's like the NIST Cybersecurity Framework. I looked at NIST and there's five components to it, and it's about cybersecurity. And I looked at this and I go, “None of this works without the right policies and procedures in place.” The security training—it's not enough just to throw it out there and tell all your people to take it. You've got to follow up, you've got to manage, and coach, and everything like that. And so I started adding this governance component to the way we sold it, presented it, and practiced what we do for our clients day in and day out. Help them develop the policies and procedures for all of the different things, the protocols.  If somebody accidentally fires off a ransomware attack, they need to know they're not going to be penalized for it. We need to know as soon as possible to stop it. And just little things like that, there's a lot that really improve the effectiveness of all of these tools and services that we provide to their clients. And unbeknownst to me, NIST, who has the cybersecurity framework, they added governance about three years ago to the other five things. And so that was kind of nice to know that we were exhibiting some thought leadership. And so when we go in, it's all well and good if you want to put these protections in and these particular products, but we're a best-of-breed company. Like one of our critical tools that's required for our clients to put in place, to buy it and use it every single day on every single computer, is what's known as an EDR. And it's basically an AI-based super turbo antivirus.  To even call it an antivirus is not doing it justice. So there's three legs to the IronTech Framework. We want to make sure that you're getting a return on your investment in IT, because that's why you buy it. If you treat IT as an expense, you need to kind of change the way you're thinking. You want to improve productivity and efficiency.Share on X The second leg is cybersecurity, because a bad cyberattack can put you out of business. I think the last stats I saw were something like 40 to 60% of businesses go out of business within two years of a significant cyberattack. And then finally, the third is governance. That's the three legs of our IronTech Framework. So part of governance is engaging with our clients' management and leadership—the CEO, finance, of course the CIO, the CISO or security officer, and maybe even the board sometimes. Really getting to know: what are your objectives, and how can we utilize our services to best help your company realize those objectives? Because for most companies, there's no other vendor they engage with as much as us.  We're talking to Susie every day. We're talking to Bill every day. We know that Mary's out sick and Steve's on vacation. I mean, when you're running help desk, stopping attacks, providing training, and all the support we provide along those lines, we get to know their company better than practically any other vendor by far. So it really helps if our clients treat us as a partner to help them realize their goals and objectives. And when all of that clicks into place, then it makes recommending things easier.Share on X “Okay, you need to replace these 30 laptops that are four years old. You're not getting an ROI on them.” “This server's five years old. Let's start thinking about replacing it.” “We have this new tool that's really excellent. We're recommending everybody get it.” And because we've developed that trust, those conversations become pretty easy. For the most part, everybody just says yes. But of course, we don't sell just to sell, especially when it comes to things like hardware. That's not really what we're here for. We're here for the day-in, day-out work: keeping things running, stopping breaches, and putting the policies and procedures in place to run your company as smoothly as possible.  Yeah. I love that. So when I had an IT back in the 2000s, I had an IT person who was a contractor, but he was very active in my business, and I always wanted to talk to him and pick his brain. What are the new things out there? How can we make our business more efficient, more effective, more attractive to employees? Cooler. I wanted to be cool. So I wanted everyone to have a PDA in the early 2000s with email on it—a PalmPilot. And we had multiple screens, and I was looking at, okay, how can we manage data in the cloud and on our server so we don't have to deal with it in the office? That kind of stuff. And I really thought about it as a great investment because it was much cheaper than hiring people. And if you give people good tools, they're going to be more motivated and more effective. So I thought it was a no-brainer.  Yes, but there's still a subset of people that treat IT as an expense. Then there are some companies that tend to put IT under the finance guy because the finance guy usually has a lot of IT experience, but never actually did it as a career or a job, right? And those situations are hard because I need CEO-level or owner-level approval, and I need a direct route to that person.  Yeah, that makes sense. So Tom, tell me, what drives growth in your business?  Yeah. From a growth perspective, for us, number one is maintaining our clients and reducing churn. Number two is—I don't know if you're asking about tactics or strategy—but of course we want to get new clients for the right reasons. So we prefer inbound strategies. We don't cold call people unless we've already contacted them in another way, if that's what you're asking.  Yeah. I'm asking what the real driver of growth is. I understand that you do marketing and inbound marketing, but what makes people want to have an IT service partner like you? Well, they understand those three pillars of the IronTech Framework. They may not believe in stakeholder capitalism, but they don't treat IT as an expense. And they understand—especially after talking to me—the true risk of being hacked. A lot of people don't understand the size and scale of that industry. It's a $10 to $12 trillion industry now.  Wow.  If it were a country, it would have the third-largest GDP. The US would be first, China second, and then the hacking industry. It is an industry that hacks at scale. So when these companies—maybe a small 10-person accounting firm in North Dakota in the middle of nowhere—get these ransomware emails and someone tries to hack them, and we alert on it and trap it, and nothing goes wrong, everything's fine… If they don't already understand it, they go, “Well, why are they trying to hack me?” And I say, “You don't understand. That email was one of 100,000 emails that got blasted out. They don't know who you are, nor do they care who you are.” They're playing a numbers game. And it's kind of like marketing. They're looking at conversion numbers. Yeah.  Let's say it's 100,000 emails. They got a list of all the certified public accountants in 10 different states. They set up the email, they send it all out, and let's say 1% become victims. And let's say they collect an average of $10,000 per victim. Well, that's a multi-million dollar payday for about a week or two of work. And then they rinse and repeat. It's done at scale, and it's a much bigger industry than that. That's just a taste of it. Some of our clients are targeted. In other words, hackers are investing time, money, and energy specifically into that company. We're one of them. Any law firm that does intellectual property law—especially around patents, manufacturing, and things like that—you've got China and other nation states not only trying to get into your client, but you're also a threat vector. You're a way to get into that client's patents and secrets.  So we've got to treat that differently. It's not just about the money. There are different types of threat actors, and we have to educate clients, bring them up to speed, and say, “Well, because of this case, you need this other service and tool that we're offering to prevent China from breaking in.” Or, “You need to follow this practice.” Maybe you don't publicly talk about one of your clients being Ford Motor Company or NVIDIA. You just keep that quiet. You don’t want that to be public knowledge. That's one of the things we do. You spent time on our website, and you didn't see a single client name on there. And that's just one of the small things we do to protect our clients' security and privacy, because privacy and security go hand in hand. Yeah. That is fascinating. So what is it that you’re trying to figure out in your business right now? What’s the big thing for you?  I think because of all the chaos in the United States, making a decision to do anything—everybody's kind of frozen. There are a lot of hiring freezes. I know we've got a freeze on right now because we're looking to see, well, do we really need to add somebody, or can we do this with AI? The hackers do the same thing. That's one of the challenges, is getting people over the hump. No matter what you do, if you've got an IT company doing your stuff and you only call them when things are broken, there's a much more profitable way to do that. You're spending more money.  So there are benchmarks in industries, right? Basically, the research—and these aren't numbers we made up, this is legitimate research from many independent sources—says the average professional service provider, like law firms, accounting firms, healthcare providers, and on and on, should be spending 6 to 12% of their revenue on IT and cybersecurity. And that's everything. I'm talking servers, wiring, cloud, security, defense—all of those things should be 6 to 12%. We know that. That's the way it works. So when we engage with a prospect and find out they're only spending 3 or 4%, then I already know they have gaps. I don't even have to do an assessment to see what they're not doing.  They're either not getting a return on investment, or they're not secure. That's it. If all the accounting firms are spending 6%, and you're only spending 4%, don't just pat yourself on the back. That's one of those moments where you should ask, “What am I missing?” Because I do that often. Someone on the management team will come up with an idea, and we all agree. Well, that's a red flag for me. I want to know: what are we missing? If we all agree on this, is there some gotcha or something we haven't uncovered? And those are some of the things we try to educate our clients on. They don't have to tell us their revenue. I can give them the numbers. I can do the math. I can show them the numbers for something like laptop replacement. Maybe it's $1,000 to $3,000 depending on the industry. If the employee using that laptop is making $100,000 a year, why are you trying to squeeze another year out of a $2,000 investment when it's hurting productivity by 10% or more? Yeah. That’s a no-brainer.  Yeah. It should be.  Yeah. It's not just in IT. I had a client years ago in civil engineering, and they had a rule that they would never keep equipment longer than four years. And they were selling equipment that still looked brand new. And I asked them, “Why are you doing this? It seems like this equipment still has a lot of life left in it. Why are you selling it or giving it back to the lease company?” And he said, “We did the math, and we figured out that this is the optimal time to replace it.” If they got rid of the equipment at that point, they wouldn't have to deal with fixing it. There would be less disruption. They would stay state-of-the-art all the time. And their clients would be impressed. And it actually worked for them. It was a high-margin civil engineering firm.  Precisely. I mean, we're so tuned into that that we're a Mac house. We all use Macs. We all have laptops, and we all have setups with screens at home and in the office. We spare no expense on that. If somebody wants an extra screen for their house—alright, here it is. We'll order it and get it there for you. We're so tuned into that, that we went all Mac back when they were still Intel Macs. And I don't know how much you know about Macs, but they were…  I have a couple. Okay. Yeah, we're Mac people too. Yeah, so they were running Intel processors. Well, Apple decided to build their own processor and moved to the M-chip. And so I bought an M1, and it was like, holy cow, everybody in the company has got to have one of these. And I don't think there was a single one more than two years old at that time. So we replaced them all. Now, the M-series generations themselves—M1, M2, M3, and on—those changes aren't as dramatic as going from Intel to the first M-series chip. But it's still unusual. I said two years, but there are probably people right now with a three-year-old laptop. But we definitely trade them in. That's where the sweet spot is on trade-in value. We rotate them every two to three years and they're out. I think mine is maybe a year old, but I'll probably keep this one for a couple more years.  By the way, you're the first IT company and MSP I've met that doesn't use PCs—you use Macs. Yeah. And I long had this theory that all the IT companies I worked with were always anti-Mac, and I never understood why. And when I got my first Mac, I realized I actually didn't need them anymore since I had the Mac.  Yeah, that's kind of funny because it really started with me during Covid. It may not have been seven years now, but whatever it was, it kind of started with Covid. And for years I was a PC guy. I tried Macs briefly back in the old MacBook days—you know, the white plastic ones? Whatever that was, 15 or more years ago.  Yeah. Classic. Very classic.  Yeah. But what I kept trying to do with a Windows laptop—and I like Dell, I had Dell XPSs, good Dell computers, and we're a Dell partner— What I could never get a Windows computer to do was seamlessly come off a docking station and then plug into another monitor at my house. It would always blue screen or something. So when I went back to a Mac, I was like, “Holy cow, it doesn't break. It doesn't mind being unplugged from a docking station. It just works.” Yeah.  And then all the other things—that they're generally built better, they have a longer lifespan, and they hold their resale value longer, and all of that. Even as old as I was, I forced myself to really get proficient at using a Mac. And when we sent everybody home during Covid, I said, “Well, everybody's going Mac.” And, oh, there was a revolt. And I said, “Just give it a few months.”  Yeah.  About half the office resisted it. And I said, “You gotta try it because I think you'll like it, and if you don't, then we'll deal with it then.” We had Linux people, PC people. So then I said, “Well, maybe we should open it up and let people pick what they want.” Yeah, I love it. Yeah. So our time is coming to an end, but if someone is running on Mac and they're finally talking to an IT service company that's not anti-Mac, and they want to connect with you immediately, where should they go and where can they learn more about Kirkham IronTech and maybe connect with you personally? The website is the best place to go. It's www.kirkhamirontech.com. Just give us a call, fill out a form, let us know what you're thinking, because we want to know what you're thinking and see if there's a fit with the way we do things. Macs started becoming important with executives. That's where we first started seeing it. So even though they may still have to run Windows, the owners and executives wanted to carry Macs for the very reasons I mentioned. So we're perfectly happy with that.  Yeah. Okay. Very good. So if you're listening to this and you enjoyed hearing about how to make your IT work—how to increase ROI, make sure you're doing cybersecurity right, and implement governance so you can use IT as a strategic tool to run your business better—then definitely reach out to Tom Kirkham. Or stay tuned to this show, because you're going to hear from other entrepreneurs who are very smart about business. And preferably do both. Tom, thank you for coming and sharing your wisdom, and thank you for listening.  Oh, it’s been my pleasure, Steve. Important Links: Tom's LinkedIn Tom's website

I sat down with Marco from MoveItOn at ConsenSys Miami to talk about something I hadn't seen before — a peer-to-peer delivery platform that turns everyday travelers into courier agents. Think Uber, but for shipping. Marco walks me through how they use smart contract escrow to build trust between strangers sending valuable items, how their M1 token powers cross-border payments, and why they just acquired a Web2 company called GlocalZone with 1.5 million app downloads to hit the ground running. We also get into the regulatory maze of operating across 100+ countries, the AI-powered security boxes they plan to place at airports and train stations, and why the last-mile delivery problem is one that AI agents simply cannot solve on their own. If you're interested in how blockchain and real-world logistics can come together to save people money and create new income streams while traveling, this one is for you. Disclaimer:Nothing mentioned in this podcast is investment advice and please do your own research. It would mean a lot if you can leave a review of this podcast on Apple Podcasts or Spotify and share this podcast with a friend. Be a guest on the podcast or contact us - https://www.web3pod.xyz/Connect:MoveItOn Website: https://www.moviton.com/ Key points with Timestamps • [00:00] Sam introduces Marco from MoveItOn, recorded live at ConsenSys Miami• [02:00] Marco's background — how writing a blockchain book for beginners pulled him into the industry• [04:00] He has three published books: Blockchain Millionaire, a crypto beginner lexicon, and a tokenization guide• [05:30] What MoveItOn is — a peer-to-peer delivery platform turning travelers into courier agents• [07:00] The founding story — a co-founder from Kazakhstan couldn't ship medical items via DHL but could carry them personally• [09:00] How blockchain fits in — smart contract escrow requires couriers to deposit the value of items they carry• [11:00] The M1 token powers payments and couriers earn staking rewards while funds are locked• [13:00] The GlocalZone acquisition — a Web2 peer-to-peer delivery app with 1.5 million downloads and 70,000 active users• [15:00] MoveItOn has been in development for about 18 months, Marco joined 8-9 months ago• [17:00] Biggest challenge is regulation — launching in 10 compliant countries first, using AI to track changing import laws• [20:00] Go-to-market strategy — partnerships with flight booking and car-sharing platforms, solving the last-mile problem with logistics companies• [23:00] B2B infrastructure and future plans for AI agent integration• [25:00] Blockchain and AI adoption across banking, medicine, and other industries• [27:00] Solving the marketplace chicken-and-egg problem through partnerships and acquisitions• [29:00] Current fundraising — private and pre-sale done, public sale in 4-6 months, seeking $4M in VC or angel funding• [31:00] Move It Boxes — AI-powered smart lockers at airports and transport hubs for contactless drop-off and pickup• [35:00] Vision for 2030 — 100+ countries, doubling the current 1.5 million user base• [37:00] Open to partnerships, investors, and remote team members — headquartered in Dubai

(00:00) — Welcome and setup: from premed dropout to med student(00:47) — Corporate grind sparks the spreadsheets vs patients question(01:30) — Rewinding to undergrad premed and the 495 MCAT during COVID(03:15) — Finances and first-gen pressure push him off the path(04:35) — Articles, AI, and volunteering rekindle interest in medicine(06:10) — Leadership draw: why physician responsibility appealed to him(07:10) — Timeline: research job, 2018 grad, 2020 MCAT, business analytics at Fordham(09:05) — Undergrad habits, no planner, and managing ADHD with better tools(11:05) — Corporate wins build confidence (Big Four, Wall Street, AVP)(12:50) — Planning the leap: savings, living at home, loans, and side investments(14:10) — Bridge/SMP at Toro Harlem: structure and guaranteed-seat criteria(16:25) — Working at Citibank while starting the master's; then going all in(17:55) — Confirming fit: brief shadowing, almost passing out, but more intrigued(18:55) — Harlem community events as a student doctor and seeing disparities(19:52) — MCAT retake to 501–502; Kaplan and official full-lengths(21:27) — SMP mirrored M1 exams; Z-score cutoff and comprehensive exam(22:45) — M1 transition is easier after the SMP run-through(23:35) — Logistics: 3.45 GPA + comp exam = seat; could apply elsewhere(24:25) — Starting a tea franchise in Astoria with partners during M1(25:35) — Brick-and-mortar stress, construction, and opening mid-semester(26:50) — Hardest part: letting go of a six-figure salary(28:05) — Would he change his path? Choosing experience over speed(29:20) — Exploring passions helps future practice and options(30:52) — Keeping doors open: medicine, consulting, and business(31:28) — Parents' reaction: skepticism to tears of pride(32:34) — Final advice: build confidence and believe in yourselfZarak shares how he walked away from premed after a 495 MCAT and an average undergrad GPA, chased a thriving corporate career, and then found his way back to medicine. A first-gen student, he talks openly about family expectations, finances, and why spreadsheets and commutes couldn't replace patient impact. He explains the planning that made his return possible: saving while living at home, using loans wisely, and enrolling in a one-year bridge/SMP at Toro Harlem that mirrored M1 exams and offered a guaranteed seat with a 3.45 GPA plus a comprehensive exam. He retook the MCAT to around 501–502 using Kaplan and official full-lengths, and found confidence through improved study systems and corporate-built habits. Now an M1, he's volunteering in Harlem, reflecting on health disparities, and even launching a brick-and-mortar tea franchise in Astoria with partners—while keeping med school first. Dr. Gray and Zarak dig into letting go of a six-figure salary, rebuilding confidence, managing ADHD with better tools, and why exploring interests outside of medicine can strengthen your future as a physician.What You'll Learn:- How a low MCAT and average GPA didn't end his med school goals- What a guaranteed-seat bridge/SMP at Toro Harlem required- How he planned the leap: savings, loans, and timing while working- MCAT retake resources he used the second time around- Balancing M1 demands with launching a brick-and-mortar business

Dave and his M1 co-hosts Lily Schmidt, Melia Patrick, Jonah Albrecht, and Anna Royer, take a field trip to Reddit's AITA sub— because self-reflection is not usually how people figure out if they're the problem. Four posts, four verdicts, and get genuinely sidetracked in the best way: there's a chlamydia anecdote Dave shares, a philosophical debate about whether watching movies at 2.5x speed makes you a bad partner, and a surprisingly earnest conversation about what med students actually owe their families when they become the designated "medical person" in the room. And (med school parents, take note) a doctor-mom posts about telling her struggling pre-med daughter she isn't cut out for medicine--and Reddit tears her a ne...helps her understand why that's not the best approach.