Podcasts about marioni

In the first ever cross-over episode between Bedrock Wine Conversations and The Wine Makers Podcast, Chris and Morgan along with Katie Bundschu (Gundlach Bundschu/Abbot's Passage) join Sam Coturri and the Wine Makers crew to discuss the first S.O.R.B.E.T..  Standing for Sonoma Organic Regenerative Biodynamic Educational Tasting the August 17th event at Fort Mason is San Fransisco will showcase wines from the 2500+ acres of responsibly farmed vineyards within the Sonoma Valley appellation. At around 20% organic, Sonoma Valley has been a historic leader in pushing forward the conversation about progressive farming practices (California agriculture in total is 4-5%) dating back to the 60s and 70s. Morgan, Katie and Sam, all multi-generational winegrowers (Katie is 6th!) explain the motivations for the tasting- chatting about the importance of farming for the next generation to putting a spotlight on the highly historic appellation of Sonoma Valley that is often confused with the greater Sonoma County. Vineyard participants will include Bedrock Vineyard, Montecillo Vineyard and Rossi Ranch while other wineries and wines will be featured from Bucklin, Donum, Hanzell, Hamel, Kamen, Guthrie Family Wines, Stewart Cellars, Repris, Fresc., Marioni, Korbin Kameron, Laurel Glen, Kivelstadt, Once&Future, Under the Wire and more.  

Imdahl, Georg www.deutschlandfunk.de, Kultur heute

Hoy les traigo una conversación genial que tuve con Massimo Marioni de ‪@fortune‬. Hablamos sobre consejos que he recibido en los negocios y en mi vida… lo que me hubiera gustado saber a los 25, y los mejores y peores consejos que me han dado. También comparto cómo defino el éxito (y sorpresa: no tiene nada que ver con ser rico o recibir premios). ¡Espero que les guste! #negocios #entrevista #éxitoempresarial #emprendedores #fortune Conoce más sobre Massimo Marioni y Fortune Magazine: https://x.com/fortunemagazine https://www.facebook.com/FortuneMagazine https://www.instagram.com/fortunemag https://www.tiktok.com/@fortune 00:00 — El mejor mentor en los negocios 2:02 — Cómo pensar en el éxito 4:37 — El mejor consejo 7:15 — El peor consejo 11:00 — Lo que me habría gustado saber antes

Marion Kattai-Kassihin – naine, ema, abikaasa, loomuliku ilu entusiast ja eestkõneleja, sertifitseeritud näojoogatreener ja veel palju muud. Marion on tasakaalukas ning võitleja hingega, enda väärtuste ja tõekspidamiste eest sirge seljaga seisja. Need iseloomuomadused on aluseks elule, millest ta unistas juba lapsepõlves ja mida täna elab - 27 aastat paarisuhtes, 2 imelist täiskasvanuealist last, kodu mere läheduses, soojad ning sügavad sõprussuhted, õnnetunne ning teha seda, mis paneb silma särama. Marion usub elukestvasse õppimisse. Talle ei piisa vaid põhiharidusena omandatud kosmeetikuõpingutest ja jaapanlanna Fumiko Takatsu Face Yoga Method näojoogatreeneri õpingutest. Ta läbib igal aastal täiendkoolitusi, nii on tal kogemusi nii lümfi- kui ka bukaalse näomassaaži, iluteipimise, gua sha näomassaaži jm. iluteemadega seotud koolitustelt. Lisaks õppis ta põhjalikult tundma ka iseennast, läbides Kai Oja juhendatud Proctor&Gallagher´i 7-kuulise Thinking Into Results programmi – ikka selleks, et iseennast veelgi paremini mõista ja olla suurepärane juhendaja oma klientidele. Juba 3 aastat ettevõtja - Näojooga Sinule on Marioni visioon, mis realiseerus väga kiiresti peale näojoogaga tutvumist. Ettevõtlust alustades on leek väga oluline - kui see eksisteerib, siis on sisemine põlemine üks komponent, mis tagab jätkusuutlikkuse. Täna on Marion iseendale tööandja ning oma vägeva Näojooga+ kogukonna eestvedaja. Tema missiooniks on tuua näojooga teadmised ja oskused iga endast hooliva naise ja meheni! Tundub, et Marionil on kõik paigas ja nüüd võib püünele jääda. Kuid ei, tema südamesooviks on anda omalt poolt panus loomuliku ilu säilitamisele ning peale kaht aastat tootearendust võib õige pea oodata ühe pikaajalise unistuse täitumist. Innovaatiline ja spetsiaalselt unejooni ennetav ILUPADI, millega on plaan vallutada kogu maailm! Marioni erinevad kursused ja töötoad leiad siit: https://naojoogasinule.ee/kursused/ Marioni e-poes olevad tooted leiad siit: https://naojoogasinule.ee/e-pood-ilutooted/ HEAD MÕTTED MARIONILT: “Kui sul tuleb see tunne, siis tee see ära.” “Botox on selline lõunapausi protseduur.” “Ei tasu teiste välimust asjatult arvustada, me ei tea kunagi, mis jälje me enda sõnadega teisele jätame.” “Õiged asjad jõuavad meieni õigetel hetkedel.” “Kui soovid näonahal vältida või ennetada kortsude ja joonte tekkimist, siis tasub enda miimikat korrigeerida.” “Hapete kasutamisega traumeeritakse nahka, et panna see kiiremini uuenema” “Me tegeleme näolapiga, mis on kogu kehast nii väike ala aga sellega tegeledes mõjutame kogu keha heaolu.” “Me ei pea olema inimestena kortsuvabad, mõni korts siin ja seal lisab isikupära.” “Ideaalis võiksime mäluda mõlema suupoolega. See kuidas mälume, mõjutab meie igemete ja hammaste tervist aga ka näo väljanägemist.” “Naised vananevad näost varem aga aeglasemalt. Kui mehed hakkavad vananema, juhtub see väga järsku.” “Ma ei soovita kosmeetika toodete kasutamist alustamist väga noorelt.” “Korts ei ole ju tegelikult probleem.” “See, mis asendis me magame, mõjutab oluliselt näo ja kaela väljanägemist.” “Kortsud ei võrdu meie vanusega, vaid väga palju meie harjumustega!” Saadet toetab Million Mindset kirjastus. Kasuta sooduskoodi "chriskala" ja saad -10% alla raamatute pealt, mida nad müüvad. Raamatud leiad www.million.ee

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.18.549357v1?rss=1 Authors: Chen, H.-J. C., Yang, A., Mazzaferro, S., Mali, I., Cahn, O., Kentistou, K., Rowley, C., Stewart, N., Seah, J. W. E., Pisupati, V., Kirwan, P., Aggarwal, S., Toyohara, T., Florido, M. H. C., Cowan, C. A., Quambusch, L., Hyvonen, M., Livesey, M. R., Perry, J. R. B., Marioni, J. C., Merkle, F. T. Abstract: Obesity substantially increases the risk of type 2 diabetes, cardiovascular disease, and other diseases, making it a leading preventable cause of death in developed countries. It has a strong genetic basis, with obesity-associated genetic variants preferentially acting in the brain. This includes the hypothalamic pro-opiomelanocortin (POMC) neurons that inhibit food intake and are stimulated by drugs that agonise glucagon-like 1 peptide receptor (GLP1R) including Semaglutide (Ozempic/Wegovy). We therefore hypothesised that drugs which selectively activate human POMC neurons would suppress appetite and promote weight loss, and that focusing on drugs already approved for use would facilitate rapid clinical translation. We therefore generated POMC neurons from human pluripotent stem cells (hPSCs) and identified enriched genes that were genetically associated with obesity and targeted by approved drugs. We found that human POMC neurons are enriched in GLP1R, reliably activated by Semaglutide, and their responses are further increased by co-administration of Ceritinib, an FDA-approved drug potently and selectively inhibiting anaplastic lymphoma kinase (ALK). Ceritinib reduced food intake and body weight in obese but not lean mice, and upregulated the expression of GLP1R in the mouse hypothalamus and hPSC-derived human hypothalamic neurons. These studies reveal a new potential therapeutic strategy for reducing food intake and body weight, and demonstrate the utility of hPSC-derived hypothalamic neurons for drug discovery. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

En este episodio platicamos con Bruno Marioni, ex futbolista argentino y actual entrenador de fútbol. Tocamos muy buenos temas como su amistad con Juan Román Riquelme, lo que implicaba jugar en Sudamérica siendo de un club mexicano, los clásicos más pasionales, su paso por Europa, Pumas en su vida y mucho más…

Bruno Marioni fue salido de Newells Old Boys, y pasó por una gran cantidad de equipos en Argentina, Portugal, España y México, dónde su ya consolidada carrera cobró un nuevo rumbo y un aire de nueva grandeza. Goleador innato, el instinto de anotador lo llevó lejos y a logar no sólo campeonar, sino a ser el último gran killer del área que tuvieron los Pumas de la universidad. Jugó en varios equipos, y muchos de ellos de gran envergadura. En Argentina en Estudiantes de la Plata, Independiente de Avellaneda y Boca Juniors. Saliendo de su país natal, fue al Sporting de Lisboa, donde además jugó Champions. En España Villarreal y Tenerife fueron los que contaron con sus magníficos goles. Y en México, Pumas, Toluca, Atlas, Pachuca y Estudiantes Tecos fueron los que lograron contarlo en sus filas. En su actual etapa como técnico, ha pasado por Tepatitlán, Venados y Pumas.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.01.530570v1?rss=1 Authors: Dabrowski, J. K., Yang, E. J., Crofts, S. J. C., Hillary, R. F., Simpson, D. J., Mccartney, D. L., Marioni, R. E., Latorre-Crespo, E., Chandra, T. Abstract: The emergence of epigenetic predictors was a pivotal moment in geroscience, propelling the measurement and concept of biological ageing into a quantitative era. However, while current epigenetic clocks have shown strong predictive power, they do not reflect the underlying biological mechanisms driving methylation changes with age. Consequently, biological interpretation of their estimates is limited. Furthermore, our findings suggest that clocks trained on chronological age are confounded by non-age-related phenomena. To address these limitations, we developed a probabilistic model that describes methylation transitions at the cellular level. Our approach reveals two measurable components, acceleration and bias, that directly relate to perturbations of the underlying cellular dynamics. Acceleration is the proportional increase in the speed of methylation transitions across CpG sites, whereas bias is the degree of global change in methylation affecting all CpG sites uniformly. Using data from 7,028 participants from the Generation Scotland study, we found the age acceleration parameter to be associated with physiological traits known to impact healthy ageing. Furthermore, a genome-wide association study of age acceleration identified four genomic loci previously linked with ageing. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.24.529873v1?rss=1 Authors: Matchett, K. P., Wilson-Kanamori, J. W., Portman, J. R., Kapourani, A., Fercoq, F., May, S., Mackey, J. B., Brice, M., Zajdel, E., Beltran-Sierra, M., Sutherland, E. F., Wilson, G. C., Wallace, S. J., Kitto, L., Younger, N. T., Dobie, R., Oniscu, G. C., Wigmore, S. J., Ramachandran, P., Vallejos, C. A., Carragher, N., Simpson, K. J., Kendall, T. J., Rule, J. A., Lee, W. J., Hoare, M., Weston, C. J., Marioni, J. C., Teichmann, S., Bird, T. G., Carlin, L. M., Henderson, N. C. Abstract: The liver has a unique ability to regenerate however in the setting of acute liver failure (ALF) this regenerative capacity is often overwhelmed and emergency liver transplantation is the only curative option. To advance our understanding of human liver regeneration and to inform design of pro-regenerative therapies, we use paired single-nuclei RNA sequencing (snRNAseq)combined with spatial profiling of healthy and ALF explant human livers to generate the first single-cell, pan-lineage atlas of human liver regeneration. We uncover a novel ANXA2+ migratory hepatocyte subpopulation which emerges during human liver regeneration, and a corollary migratory hepatocyte subpopulation in a mouse model of acetaminophen (APAP)-induced liver regeneration. Importantly, interrogation of necrotic wound closure and hepatocyte proliferation across multiple timepoints following APAP-induced liver injury in mice demonstrates that wound closure precedes hepatocyte proliferation. 4-D intravital imaging of APAP-induced mouse liver injury identifies motile hepatocytes at the edge of the necrotic area, enabling collective migration of the hepatocyte sheet to effect wound closure. Depletion of hepatocyte ANXA2 expression reduces HGF-induced human and mouse hepatocyte migration in vitro, and abrogates necrotic wound closure following APAP-induced mouse liver injury. Taken together, our work dissects unanticipated aspects of liver regeneration, demonstrating an uncoupling of wound closure and hepatocyte proliferation and uncovering a novel migratory hepatocyte subpopulation which mediates wound closure following liver injury. Therapies designed to promote rapid reconstitution of normal hepatic microarchitecture and reparation of the gut-liver barrier may open up new areas of therapeutic discovery in regenerative medicine. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

A new research paper was published in Aging (listed as “Aging (Albany NY)” by MEDLINE/PubMed and “Aging-US” by Web of Science) Volume 14, Issue 23, entitled, “DNA methylation GrimAge version 2.” Researchers Ake T. Lu, Alexandra M. Binder, Joshua Zhang, Qi Yan, Alex P. Reiner, Simon R. Cox, Janie Corley, Sarah E. Harris, Pei-Lun Kuo, Ann Z. Moore, Stefania Bandinelli, James D. Stewart, Cuicui Wang, Elissa J. Hamlat, Elissa S. Epel, Joel D. Schwartz, Eric A. Whitsel, Adolfo Correa, Luigi Ferrucci, Riccardo E. Marioni, and Steve Horvath from the University of California Los Angeles, Altos Labs, University of Hawaii at Manoa, Fred Hutchinson Cancer Research Center, University of Edinburgh, National Institute on Aging, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Harvard T.H. Chan School of Public Health, University of California – San Francisco, and the University of Mississippi Medical Center previously described a DNA methylation (DNAm) based biomarker of human mortality risk DNAm GrimAge. In their current study, the researchers describe version 2 of GrimAge (trained on individuals aged between 40 and 92) which leverages two new DNAm based estimators of (log transformed) plasma proteins: high sensitivity C-reactive protein (logCRP) and hemoglobin A1C (logA1C). “To arrive at version 2 of GrimAge, we developed two additional DNAm based surrogates for plasma proteins that are widely used in the clinic (DNAm logCRP and DNAm logA1C).” The team evaluated GrimAge2 in 13,399 blood samples across nine study cohorts. After adjustment for age and sex, GrimAge2 outperforms GrimAge in predicting mortality across multiple racial/ethnic groups (meta P=3.6×10-167 versus P=2.6×10-144) and in terms of associations with age related conditions such as coronary heart disease, lung function measurement FEV1 (correlation= -0.31, P=1.1×10-136), computed tomography based measurements of fatty liver disease. The researchers presented evidence that GrimAge version 2 also applies to younger individuals and to saliva samples where it tracks markers of metabolic syndrome. DNAm logCRP is positively correlated with morbidity count (P=1.3×10-54). DNAm logA1C is highly associated with type 2 diabetes (P=5.8×10-155). DNAm PAI-1 outperforms the other age-adjusted DNAm biomarkers including GrimAge2 in correlating with triglyceride (cor=0.34, P=9.6×10-267) and visceral fat (cor=0.41, P=4.7×10-41). Overall, the team demonstrated that GrimAge version 2 is an attractive epigenetic biomarker of human mortality and morbidity risk. “GrimAge2 will not replace existing clinical biomarkers. Rather, GrimAge2 complements existing clinical biomarkers when evaluating an individual's aging rate.” DOI: https://doi.org/10.18632/aging.204434 Corresponding Author: Steve Horvath - shorvath@mednet.ucla.edu About Aging-US: Launched in 2009, Aging (Aging-US) publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at www.Aging-US.com​​ and connect with us: SoundCloud – https://soundcloud.com/Aging-Us Facebook – https://www.facebook.com/AgingUS/ Twitter – https://twitter.com/AgingJrnl Instagram – https://www.instagram.com/agingjrnl/ YouTube – https://www.youtube.com/agingus​ LinkedIn – https://www.linkedin.com/company/aging/ Reddit – https://www.reddit.com/user/AgingUS Pinterest – https://www.pinterest.com/AgingUS/ For media inquiries, please contact media@impactjournals.com.

La ex dupla de ataque de la lepra dialogó con Carolina Coscarelli y equipo de La Red #Rosario 98.3: Los goles en el clásico rosarino a Central, el momento de Lionel Scaloni ex compañero leproso y actual DT de la Selección Argentina, la llegada de Heinze al parque y mucho más! Una charla distendida entre amigos en marco del aniversario número 119 del club de sus amores. Dale play!

Un "Tiro Directo" con Bruno Marioni, ex jugador de Pumas y actual técnico de Tepatitlán. ¿Pumas está obligado a salir campeón? ¿Está bien que no haya ascenso y descenso? ¿Hay más presión jugar en uno de los cuatro grandes? Escucha esta entrevista exclusiva con Gustavo Mendoza. Sólo por futvox, hablamos futbol. ¡Conecta con futvox! Twitter: @FutvoxOficial Instagram: @futvoxoficial TikTok: @futvoxoficial Facebook: @futvoxoficial Learn more about your ad choices. Visit megaphone.fm/adchoices

Tänase saate külaline on Aldo Maksimov, kes kolis koos abikaasa Marioni ning laste ja loomadega Kreeka saarele Samosele elama. Aldo jaoks on Kreeka olnud südamelähedane juba pikka aega, heas mõttes on selle pisikuga nakatunud ka tema abikaasa ja lapsed. Lapsed muuseas olid vägagi päri Samosele kolimisega – küllap oli põhjus tõigas, et sealmail on reisitud väga palju. Aldo leiab, et nad saavad Samosel anda lastele parema lapsepõlve ning ka vanemad on õnnelikumad kui Eestis. Nagu Aldo ise ütleb: Kreekas on alles jäänud tuum, elamise päris algne idee. Praegu peab perekond Samosel loome- ja puhkemaju, kuhu jõuab üsnagi palju eestlasi. Saates räägitakse veel näiteks Samosel maja üürimise võimalustest ja hinnast, külaelust, bürokraatiast ja selle saarekese erilisusest. Vestlust juhib Liina Metsküla.

Martín del Palacio y Luis Herrera charlan con el ex delantero campeón con Pumas en la Liga MX y con Boca en la Copa Libertadores, ahora director técnico tras su paso por el automovilismo.Este programa se grabó en vivo en Twitch. ¡Sigue nuestros canales! Estamos en luisrha y Martindelpalacio.---Furnkorama by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/3788-funkoramaLicense: http://creativecommons.org/licenses/by/4.0/ See acast.com/privacy for privacy and opt-out information.

BRUNO SHO TE AMO: ¡Llegamos al episodio #50 de AGDG Radio! Y como no podía ser de otra forma, les traemos ¿la mejor editorial? en la historia de este podcast, dedicada por supuesto, a nuestro invitadazo de hoy: El Barullo Marioni, último campeón de goleo con Pumas platicó con Jon, Diana Alonso, Jan Campos, Ale Celada y el Pumachi recién bañado de su llegada al equipo con dudas, los mejores momentos que vivió acá, la Sudamericana, cuando América lo contactó, expresó su deseo por volver al banquillo de los nuestros y mucho, mucho más. Disfruten de esta edición especial de su programa de confianza del Club Universidad Nacional, gracias por escucharnos siempre. 

Un proyecto del grupo Tucucuentos Solidarios del Ente Cultural de Tucumán, que contiene más de 50 audiocuentos de autores locales en las voces de las narradoras Alejandra Jiménez, Olga Martínez, Neli Santillán, Gloria Argañaraz, Olga Bonano, Silvia Israilev y Graciela Palavecino.

¿La presión de un jugador cambia cuando no hay descenso sino multa?

El exdelantero y actual entrenador pasó por Un Plan Simple y aseguró que le gustaría dirigir en el fútbol argentino.

Su aparición en la primera de Newell´s Old Boys de Rosario lo consagró como uno de los mejores delanteros de fines de los 90 del fútbol vernáculo. Luego emigró al fútbol europeo donde hizo escala en Portugal y España. A pesar de sus pasos por Independiente y Boca su carrera brilló en el futbol mexicano donde marcó una época hasta transformarse en director técnico. Hoy, nos vista en Tanto por decir, Bruno Marioni.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.21.346635v1?rss=1 Authors: Pluchino, S., Hamel, R., Peruzzotti-Jametti, L., Ridley, K., Testa, V., Yu, B., Rowitch, D., Marioni, J. Abstract: Innate immune responses following spinal cord injury (SCI) participate in early secondary pathogenesis and wound healing events. Here, we used time-resolved scRNAseq to map transcriptional profiles of SC tissue-resident and infiltrating myeloid cells post-SCI. Our work identifies a novel subpopulation of Fabp5+ inflammatory myeloid cells, comprising both resident and infiltrating cells and displaying a delayed cytotoxic profile at the lesion epicentre, which may serve as a target for future therapeutics. Copy rights belong to original authors. Visit the link for more info

La receta para que Bruno Marioni y Pumas lograran el campeonato, secretos de Copa Libertadores y... ¿América vs Pumas o América vs Chivas? Edición de lujo en La Pelota al que sabe

There’s more than one way to measure how fast you’re ageing. There’s chronological age - the number of years you’ve been alive - and then there’s biological age, which you can think of as the total damage your body has accumulated over the years. Your chronological age may differ from your biological age, in which case it’s interesting to understand why. The good news is you can reduce your biological age by improving your lifestyle, which in turn can lengthen lifespan and healthspan. The question is, then, how to quantify biological age? On this podcast, NBT Scientific Director Megan Hall talks about PhenoAge: a measure of biological age that can be determined by analyzing a shortlist of common blood markers. We talk about why PhenoAge is important and valid as a reliable measure of biological status, and how you can get your PhenoAge score. Megan also offers tips for improving your PhenoAge once you’ve got your baseline. This episode has a ton of information, so be sure to follow along with Megan’s outline. Here’s the outline of this interview with Megan Hall: [00:00:25] Arden Pope, PhD; Studies on the effects of air pollution on human health. [00:01:15] Puppy update. [00:05:54] Is ageing a disease? Article: Bulterijs, Sven, et al. "It is time to classify biological aging as a disease." Frontiers in genetics 6 (2015): 205.   [00:06:35] Primary vs secondary ageing. [00:08:02] Book: Lifespan: Why We Age - and Why We Don't Have To, by David A. Sinclair PhD. [00:08:16] Ken Ford; STEM-Talk Podcast. Ken Ford on the NBT Podcast: Optimal Diet and Movement for Healthspan, Amplified Intelligence and More. [00:09:19] Measuring ageing. [00:13:09] Theories of ageing - more than 300 theories; Articles: Tosato, Matteo, et al. "The aging process and potential interventions to extend life expectancy." Clinical interventions in aging 2.3 (2007): 401. 2. da Costa, Joao Pinto, et al. "A synopsis on aging—Theories, mechanisms and future prospects." Ageing research reviews 29 (2016): 90-112. 3. Jin, Kunlin. "Modern biological theories of aging." Aging and disease 1.2 (2010): 72.  [00:13:34] Grandmother hypothesis; Podcast: The Postmenopausal Longevity Paradox and the Evolutionary Advantage of Our Grandmothering Life History, with Kristen Hawkes, PhD. [00:14:48] Program Theories and Damage Theories. [00:17:45] Epigenetic clock theory of aging; Steven Horvath; Study: Horvath, Steve, and Kenneth Raj. "DNA methylation-based biomarkers and the epigenetic clock theory of ageing." Nature Reviews Genetics 19.6 (2018): 371.  [00:19:02] Steven Horvath's TEDx talk: Epigenetic Clocks Help to Find Anti-Aging Treatments. [00:20:47] Book: Masters of Doom: How Two Guys Created an Empire and Transformed Pop Culture, by David Kushner. [00:21:43] DNA methylation; Article: Horvath, Steve. "DNA methylation age of human tissues and cell types." Genome biology 14.10 (2013): 3156. [00:23:13] Offspring of semi-supercentenarians have lower epigenetic age; Study: Horvath, Steve, et al. "Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring." Aging (Albany NY) 7.12 (2015): 1159.  [00:23:36] Methylation based biological age associated with: 1.  breast cancer risk: Kresovich, Jacob K., et al. "Methylation-based biological age and breast cancer risk." JNCI: Journal of the National Cancer Institute 111.10 (2019): 1051-1058. 2. Frailty: Breitling, Lutz Philipp, et al. "Frailty is associated with the epigenetic clock but not with telomere length in a German cohort." Clinical epigenetics 8.1 (2016): 21; 3. All-cause mortality: Marioni, Riccardo E., et al. "DNA methylation age of blood predicts all-cause mortality in later life." Genome biology 16.1 (2015): 1-12 and Christiansen, Lene, et al. "DNA methylation age is associated with mortality in a longitudinal Danish twin study." Aging cell 15.1 (2016): 149-154. [00:24:46] PhenoAge as a biomarker of ageing for lifespan and healthspan; Study: Levine, Morgan E., et al. "An epigenetic biomarker of aging for lifespan and healthspan." Aging (Albany NY) 10.4 (2018): 573. [00:29:06] Nine blood markers that make up PhenoAge. [00:29:57] PhenoAge related to COVID-19; Study: Kuo, Chia-Ling, et al. "COVID-19 severity is predicted by earlier evidence of accelerated aging." medRxiv (2020).  [00:30:34] Combining PhenoAge with DNA methylation data as a predictor of mortality. [00:33:28] Episode 59 of HumanOS podcast: Are You Biologically Older or Younger Than Your Chronological Age? [00:33:58] Dr. Josh Turkett’s 4-quadrant model. [00:34:00] Lifestyle factors that accelerate ageing: Sleep: Li, Xiaoyu, et al. "Association between sleep disordered breathing and epigenetic age acceleration: Evidence from the Multi-Ethnic Study of Atherosclerosis." EBioMedicine 50 (2019): 387-394; Socioeconimic status, childhood and adult adversity: Liu, Zuyun, et al. "Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study." PLoS medicine 16.6 (2019): e1002827; Education: Zhao, Wei, et al. "Education and lifestyle factors are associated with DNA methylation clocks in older African Americans." International journal of environmental research and public health 16.17 (2019): 3141. [00:35:59] Protein; Podcast: Why You’re Probably Not Eating Enough Protein (How to Know for Sure), with Megan Hall. [00:36:50] Book: The Good Gut: Taking Control of Your Weight, Your Mood, and Your Long-term Health, by Justin Sonnenburg and Erica Sonnenburg. [00:37:23] Bloodsmart.ai. [00:38:35] Patreon: nbt.link [00:39:33] Age reversal possible in humans? Study: Fahy, Gregory M., et al. "Reversal of epigenetic aging and immunosenescent trends in humans." Aging cell 18.6 (2019): e13028.  [00:40:15] Simon Marshall, PhD. [00:41:00] Interpreting your blood markers to understand PhenoAge. [00:46:11] PhenoAge vs Predicted Age.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.31.231126v1?rss=1 Authors: McCartney, D. L., Chasman, D. I., Visscher, P. M., Muniz-Terrera, G., Cox, S. R., Russ, T. C., Marioni, R. E., Mur, J. Abstract: Genetic variation in VKORC1 is associated with differences in the coagulation of blood and consequentially with sensitivity to the drug warfarin. Variation in VKORC1 has also been linked to parental dementia. However, it is unclear whether the relationship persists for the diagnosis in patients themselves, whether the association holds only for certain forms of dementia, and if those taking warfarin are at greater risk. Here, we use data from 211,423 participants from UK Biobank to examine the relationship between VKORC1, risk of dementia, and the interplay with warfarin use. We find that the T-allele in rs9923231 confers a greater risk for vascular dementia (OR=1.28, p=0.0069), but not for general dementia (OR=1.04, p=0.21) or Alzheimer dementia (OR=1.05, p=0.35), and that the risk of vascular dementia is not affected by warfarin use in carriers of the T-allele. Our study reports for the first time an association between rs9923231 and vascular dementia, but further research is warranted to explore potential mechanisms and specify the relationship between rs9923231 and features of vascular dementia. Copy rights belong to original authors. Visit the link for more info

El jugador que estaba comprometido dentro y fuera de la cancha. 
Siempre entregado a su profesión y la vida le recompensó con una carrera llena de éxitos.

El ex capitán rojinegro hablo sin tapujos de su paso por el Atlas, su llegada y sus polémicas salidas, pero al final de cuentas su amor por los colores no cambian.

Il manager di un'azienda è come uno skipper che pianifica la rotta, decide i turni, aiuta alle manovre; mette a disposizione la propria esperienza per permettere all'equipaggio di superare la tempesta: parola di Stefano Marioni presidente Extrapola

Bruno Marioni no sabe por qué salió de Pumas , charla en el Tiradero

Charla en el Tiradero con dos campeones de la liga mx Bruno Maroni y Hugo Castillo, además Pablo Ramírez nos cuenta sus iniciois en los medios comunicación , la psicologa Ofelia Márquez nos da consejos para la cuarentenay el padre Juan Jose da mensaje en estos momentos dificiles

Llegó el segundo episodio de {Protagonistas}, en este caso estuvimos dialogando con el Director General del mítico Teatro Municipal Coliseo Podestá, Gastón Marioni. En esta charla no solo vas a encontrar sus experiencias de vida, sino también lo que significa generar y administrar la cultura de un espacio tan importante. ENJOY!

A pocos días del Boca-River, por un pasaje a la final de la Copa Libertadores 2019, hablamos con Bruno Marioni. Campeón, de ese mismo torneo, con el "Xeneize" en 2007. Se puso en el lugar de Alfaro unos minutos y nos dijo como pararía el equipo para el martes. Sueña con dirigir en el fútbol argentino, sobre todo, en los clubes por lo cual tuvo un pasaje como jugador. ¿Su complicada salida de Pumas de México lo afectó en su carrera? Escuchá.

Charla en Radio Universidad de La Plata (#AM1390)

Bruno Marioni: "Fue el mejor partido de Pumas desde que yo estoy"

Bruno Marioni : Rodrigo estaba molesto por la expulsión a Kevin Escamilla y nada más.

Bruno Marioni : El plantel está mal anímicamente

Bruno Marioni se agarra a golpes con un aficionado

️Bruno Marioni quiere la final de copa

La Copa no tan mX regresa con sus semifinales de alarido... de Xolo. El América busca el primer trofeo para armar el doblete y enfrente tiene a los Xolos de Tijuana, mientras que los Pumas de Marioni ven en este torneo su única oportunidad de tener dignidad en el semestre (porque ganarle a Chivas ya no es proeza).

Bruno Marioni ; Vamos a calificar

Bruno Marioni vs José Saturnino Cardozo

Bruno Marioni: "Dejamos ir una oportunidad para seguir con la idea de calificar"

Bruno Marioni : Tuvimos errores y nos costó caro

Bruno Marioni: "Hoy el rival nos superó, fue mejor"

Ilusiona a Marioni enfrentar a Maradona en la Copa MX

Bruno Marioni: "Pagamos caro los errores ante el equipo que mejor juega"

Osorio sin rumbo, Marioni vive un sueño, Simeone inmortal, Queiroz por el reto con Colombia, el arte de escoger un equipo de futbol hoy en la Locomotora.

Bruno Marioni: "Quiero que mi equipo sea protagonista

Marioni ve preparado a Pumas para competirle al América

Bruno Marioni: El equipo recuperó la mística

It’s not uncommon to read comparisons between Albert Einstein and Paul Marioni, artist and one of the founders of the Studio Glass movement, many based on their shared lifelong fascination with light. Known as an innovator in the glass world, Marioni has been pushing the limits of his medium for five decades, redefining what is possible not only in process but content. He says: “I work with glass for its distinct ability to capture and manipulate light. While my techniques are often inventive, they are only in service of the image.”    A surrealist whose work addresses issues of nature, identity, and emotion, Marioni relies upon dreams as well as political and social convictions to make statements, causing us to forget the unfair advantage that working with glass affords. Using material that is inherently beautiful, the artist inspires people to think rather than telling them what to think. Marioni’s work can be found in collections including the Smithsonian American Art Museum, Washington, D.C.; The Corning Museum of Glass, Corning, New York; and the Museum of Arts and Design, New York, New York.   Marioni, who graduated in 1967 from the University of Cincinnati, Ohio, is a Fellow of the American Crafts Council and Glass Art Society Lifetime Achievement Award recipient. He has received three fellowships from the National Endowment of the Arts and has taught at schools worldwide including the Penland School of Crafts, Bakersville, North Carolina; Pilchuck Glass School, Stanwood, Washington; the Glass Furnace, Istanbul, Turkey; and more recently at Soneva Art and Glass in the Maldives.   At 77, Marioni remains passionate about the “road show,” a grassroots effort started by artists like himself, Fritz Dreisbach, Dale Chihuly, and Richard Marquis, to spread knowledge and enthusiasm about glass to anyone who showed interest. “I’ve worked in glass all but three years of my life. What was I thinking to get into a field with no history, no books, no teaching? Obviously I wasn’t thinking. But we built the Studio Glass movement on cooperation, not competition, because there was no past. There was nothing for us to get. And we’ve barely scratched the surface of what can be done.”   In addition to gallery work, Marioni has produced over 100 public and private commissions in both cast glass and terrazzo. From his studio in Mexico, the artist currently works on the biggest commission of his career for the $52 million Bellevue, Washington, light rail station. Its train serves business powerhouses of the Pacific Northwest including Microsoft and Boeing. Selected as lead artist for the project through a national competition, Marioni is designing 3000+ square feet of art glass for the platforms as well as the terrazzo floors.   

Marioni, orgulloso de su debut al frente de Pumas

Las novelas de los Nico's llegan a su fin, lo que le espera a Benedetti en el mundo de la farándula de Televisa, Layún cerrado con Rayados, Marioni debuta ganando en copa, y el gran momento de Jimenez.

Pumas inicia era de Marioni ante Atlas , estpo y màs en la previa de la jornada 4 de la Copa mx

Bruno Marioni se siente capacitado para dirigir a Pumas sin importar su pasado de gloria como jugador del equipo

Los números de Bruno Marioni como técnico

Bruno Marioni : Hay que recuperar un poquito el orden en Pumas

¿Cómo afrontar el éxito y el fracaso?, ¿cómo alcanzar la inspiración y levantarnos frente a las adversidades? Sobre esto y otros temas dialogó Silvia Pérez con Diego Pasjalidis, ingeniero industrial y experto en estrategias e innovación, autor de "Inspiración extrema: estrategias, innovación y magia se conjugan para desarrollar mejores negocios". Además, también recibió la visita del director y docente teatral, Gastón Marioni.

Charla muy amena con Bruno Marioni. Platicamos de sus inicios como futbolista, títulos con Pumas y su visión del legado que quiere dejar como entrenador. Imperdible por donde se le vea.

On May 12 at Chihuly Garden and Glass in Seattle, Washington, a full capacity audience of 275 guests attended Pilchuck Celebrates and toasted the 2016 Honorees. Glassblowing pioneer Dante Marioni, 52, was awarded The Libenský | Brychtová Award, which acknowledges extraordinary talent and high achievement in the world of contemporary glass. Marioni took the glass world by storm at age 19 with his exacting and intuitive command of both Venetian design and technique. The resulting monumental Post Modern sculpture referred to vessels and paid homage to glassblowing itself. His early aesthetic signature included graceful form, impeccable finish, and the use of solid opaque colors, all of which made his work instantly recognizable. Always looking for a new challenge, Marioni’s series are short-lived. The natural evolution of process and form led to an aesthetic shift away from opaque, bold color to an exploration of pattern created through Venetian techniques such as reticello and latticino in transparent glass. Marioni’s current work beguiles the viewer with its intricacy, beauty, and perfection of form, revealed in sculptural vessels that are inspired by the stylized leaf as found in the decorative arts. Marioni’s work will be exhibited in Classical, Native, and Pop Cultures, on view September 2 – 30 at Schantz Gallery, Stockbridge, Massachusetts, along with the work of Preston Singletary and Richard Marquis. His solo exhibition, In a Breath, opens November 4 at Ken Saunders Gallery, Chicago, Illinois, during the first week of SOFA and runs through December 2016.    

Marioni tütar Karita sõidab veebitutvuse ajel Afganistani ja elab seal mõnda aega, kuid lakkab siis ema kirjadele vastamast ning side temaga katkeb. Kui Karita tütre otsinguil Kabuli jõuab ei oska ta tegelikult ettegi kujutada missugine maailm teda seal ees ootab. Kohaneda tuleb eurooplase jaoks vägagi harjumatute tingimuste ja erineva ühiskonnaga. Õnneks leidub abivalmis inimesi tänu kellele saab Marion siiski lootust tütre leidmiseks. See protsess on aga kõike muud kui lihtne ja ohutu. (Aleksander Aina. Pimeduses kulgeb tee. Loeb Kristi Aule.)

Boyd Hilton is Joined this Week by Massimo Marioni, Pete Wood and Josh Landy for transfer discussions, debates of Arsene Wengers successes and failures, and other things Arsenal related currently! Produced by Josh Landy A Playback Media Production playbackmedia.co.uk Get our FREE apps at arsenalpodcast.net

If you experience any technical difficulties with this video or would like to make an accessibility-related request, please send a message to digicomm@uchicago.edu. Tom Marioni talks about The Act of Drinking Beer with Friends is the Highest Form of Art...and does some stand-up.

Senior Curator of Modern and Contemporary Art Vesela Sretenovic introduces the installation Eye to Eye: Joseph Marioni at the Phillips, on view Oct. 22, 2011-Jan. 29, 2012. Thirteen glowing paintings by Marioni are surrounded by about 40 works from the museum's collection that trace the development of color and light in modern painting. This is the first Washington, D.C., exhibition of Marioni's work. Organized as part of The Phillips Collection's 90th anniversary. More about this installation: http://www.phillipscollection.org/anniversary/joseph_marioni.aspx

Senior Curator of Modern and Contemporary Art Vesela Sretenovic introduces the installation Eye to Eye: Joseph Marioni at the Phillips, on view Oct. 22, 2011-Jan. 29, 2012. Thirteen glowing paintings by Marioni are surrounded by about 40 works from the museum's collection that trace the development of color and light in modern painting. This is the first Washington, D.C., exhibition of Marioni's work. Organized as part of The Phillips Collection's 90th anniversary. More about this installation: http://www.phillipscollection.org/anniversary/joseph_marioni.aspx