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Today, let's look at how your belief in your own unworthiness can serve as a self-preservation strategy, especially a strategy to preserve your relationships. And then, let's look at how knowing this, can actually make you believe you are worthy.
Send us a textFive heavy hitters enter a blind tasting; a tie forces a live tiebreak and the crown goes to Old Man Winter With a prestige French oak finish. We trade hype for flavor, argue proof vs. balance, and learn how availability shapes a worthy Scotchy Bourbon Boys “Bourbon of the year.”• sponsors thanked and distillery updates shared• lineup set for the blind: five bourbons, one wild card on the side• simple scoring rules agreed, color coding to prevent bias• first-pass notes on cola, peanut, vanilla, and fruit-forward profiles• proof chat and how it affects palate, not just heat• debate on noses vs palates, dryness vs sweetness• tally confusion resolved, two-way tie identified• audience tiebreak selects Old Man Winter as winner• value and availability weighed against rarity and price• honorable mentions and how oxidation changes bottles over timeMake sure that you leave us good feedback on Apple and iHeart and Spotify five-star rating and everything. Leave a review and then become members.What happens when you strip away labels, lock in a scoring system, and let the glass do the talking? We gathered the full crew, poured five of the year's most talked-about bourbons completely blind, and chased the truth through cola notes, peanut vibes, dessert-like vanilla, and bright, fruit-forward finishes. The lineup was stacked: Knob Creek 21, Russell's Reserve 13 (2025), A Midwinter Night's Dram, Cathedral French Oak, and Old Man Winter from Preservation. Expectations were sky high for the heavy hitters—but the scoreboard had other plans.We walk you through the tasting rules, the early favorites, and the turning point when pour number three changed the room's mood. Proof chasers met balance seekers as a silky 90s-proof contender outperformed its label, while a 110-proof nose bomb turned out more polarizing on the palate than predicted. Cathedral French Oak cast a spell on the nose. Knob 21 delivered oak-driven structure. Russell's 13 flashed that rich sweetness many love. Midwinter offered juicy fruit and charm. But the question we kept asking was simple: which glass makes you want another pour?By the end, scores tied between two colors and we pulled in a live audience to break it. The winner? Old Man Winter—an underdog that paired layered fruit, spice control, and a welcoming finish with the practical upside of being findable at retail. We dig into why availability matters for a “Bourbon of the Year,” what blind tasting reveals about our biases, and how time in the bottle can flip your rankings weeks later. Stick around for honorable mentions, lessons learned from oxidation, and a reminder that great whiskey doesn't always wear the most expensive label.If you enjoyed this blind battle, follow the show, share it with a bourbon friend, and drop your own top pick of the year in a review. Your palate belongs in this conversation.voice over Whiskey Thief Add for SOFLSupport the showhttps://www.scotchybourbonboys.com The Scotchy bourbon Boys are #3 in Feedspots Top 60 whiskey podcasts in the world https://podcast.feedspot.com/whiskey_podcasts/
Send us a textWhat if the hardest things in your life also come from a good God—and are meant to fortify you? We dive into Job 10 with open Bibles and honest voices, tracing how suffering, justice, and mercy weave through one of Scripture's rawest prayers. Job refuses the easy answers. He won't blame fate or the devil. He stands before a perfect Judge who marks every sin and still calls that Judge good. That tension becomes a doorway to deeper trust, not shallow denial.We press into a hard question that won't go away: is annihilation justice? Our take is clear and carefully argued—equal penalties for unequal guilt flatten morality and contradict the very nature of divine justice. The thief and the butcher cannot meet the same end if God's judgment is truly right. From there, the room shifts to hope. Romans 8 breaks in like daylight: who can bring a charge against God's elect when Christ intercedes? The legal language Job feels—charge, acquit, condemn—finds its answer at the right hand of God, where a risen Savior pleads for his people.Job 10:15 becomes the heart of the conversation: “If I be wicked, woe unto me; and if I be righteous, yet will I not lift my head.” That's the shape of real humility. When guilty, we bow. When counted righteous, we bow lower, because the righteousness is borrowed, not earned. We talk about chastisement versus condemnation, why nothing escapes God's notice, and how providence can bruise and heal in a single act. We also tackle assurance head-on: if God saves, he sustains. Preservation belongs to Christ, not our fragile resolve.If you're wrestling with pain, justice, or the fear of being seen by a holy God, this conversation offers both gravity and grace. Listen, share with a friend who needs courage, and if it serves you, subscribe and leave a review to help others find the show. What part moved you most?Support the showBE PROVOKED AND BE PERSUADED!
Happy New Year, Retrospectors! We'll return with new episodes from Monday 5th January, but in the meantime the team have been choosing their favourite episodes from 2025 that are worthy of a second listen. First up, Olly has selected our conversation about ‘New Coke'. Coca-Cola was approaching its 100th birthday on 23rd April, 1985, when it unveiled a new beverage at New York City's Lincoln Center: the ‘smoother, rounder, bolder' flavour of ‘New Coke'. The success of Diet Coke had fragmented the market, and, in response to Pepsi's aggressive marketing campaigns targeting younger consumers, Coke had sought to introduce a sweeter formula. But, instead of offering the new formula alongside the original, they made the catastrophic decision to discontinue their classic recipe, known as Merchandise 7X. The company had conducted extensive taste tests involving 190,000 consumers, which indicated a preference for the new formula. However, these tests overlooked the deep emotional connection many had with the original Coke. Protest groups like the Society for the Preservation of the Real Thing and Old Cola Drinkers of America, founded by Gay Mullins, emerged, reflecting the public's dissatisfaction, and, just 79 days after the launch, on July 11th, 1985, Coca-Cola held a press conference to announce the return of the original formula - now branded as "Coca-Cola Classic." In this episode, Arion, Rebecca and Olly reveal those hardcore cola fans who stockpiled soda like it was gold; uncover the psychiatrist's opinion that Coke's most committed customers were behaving as if they'd experienced a bereavement; and consider the conspiracy theories that suggest Coca-Cola engineered the whole debacle deliberately… Further Reading: • ‘Coke, The Taste That Distresses' (The Washington Post, 1985): https://www.washingtonpost.com/archive/lifestyle/1985/06/07/coke-the-taste-that-distresses/1f0758dd-98a2-4a9d-ae1c-c188c2228354/ • ‘New Coke Didn't Fail. It Was Murdered' (Mother Jones, 2019): https://www.motherjones.com/food/2019/07/what-if-weve-all-been-wrong-about-what-killed-new-coke/ • ‘1985: Coca-Cola launches new Coke' (CBS Evening News, 1985): https://www.youtube.com/watch?v=a8j97dOLsyk #80s #Advertising #Mistakes #Food Love the show? Support us! Join
Send us a textWhat if blessing doesn't wait for the breakthrough but lives right in the middle of the struggle? We open with a candid story of chronic pain and an unwavering decision to keep walking, smiling, and asking God the hard questions. That honesty leads us straight into the spine of this conversation: remembrance. We ask whether the stored memory of God's faithfulness could hold us if today feels empty—whether gratitude can outlast silence and whether praise can rise even when we feel far from Him.From there we step into Job 10. Job's vivid language—poured like milk, curdled like cheese, clothed with skin and fenced with bones—becomes a theology of design. He distinguishes the person from the body, spotlighting the soul God animates. It's a bracing counter to our era's obsession with appearance and comfort. We talk about knowing Scripture not as a recital contest, but as a way to know the Lord: the Spirit brings truth to remembrance, and understanding outruns mere recall. That shift relieves pressure and deepens devotion.We also linger on the “lost sheep” as a lens of divine ownership: being lost assumes you already belonged to the Shepherd. Job's confession—You granted me life and favor, and Your visitation preserved my spirit—draws a straight line to the gospel's core. Life is granted, not earned. Favor is undeserved, not generic. Preservation is personal, not abstract. Across the conversation, we emphasize the unity of salvation through the ages: grace through faith, not performance or ritual, grounding our hope beyond momentary outcomes.By the end, you'll have a richer vision of God's sovereignty, human frailty, and the surprising blessing of trust forged in affliction. Press play to meditate on Job 10, trade anxiety over verse recall for confidence in God's character, and join us in praying boldly for healing while resting in the Shepherd who keeps His own. If this moved you, follow the show, share it with a friend, and leave a review telling us what you will remember this week.Support the showBE PROVOKED AND BE PERSUADED!
Hello and welcome to another episode of the Rarified Heir Podcast. Today, we are doing something different but not totally unprecedented. Last year in 2024, we presented a bonus episode, recorded live at the Texas Theater in Dallas, Texas with Ernie Kovacs award winner, Gerald Casale from Devo at VideoFest. This year, we'd like to present this year's VideoFest's Ernie Kovacs Award recipient, comedian Fred Armisen. This is just one of the ways we keep the legacy of both Ernie and Edie Adams going and frankly, it's really a major impetus for this podcast itself. How better to keep someone's legacy alive than via the children of those who knew them best, their children? Recorded on November 23, in the very same theater where Lee Harvey Oswald was arrested for the assassination of President John F. Kennedy, exactly 62 years prior, this episode exists only because of one person and we wanted to thank Dev Shapiro of Selig News for his recording. You see, we recorded this directly from the sound board for ideal sound quality but when we got the digital files, they were corrupted and unusable. Thankfully, it was Dev to the rescue and while Dev was not recording directly from the sound board, I think we can all forgive the minor audio issues because well, he saved our bacon by just being there. Preservation is key and we thank Dev for making that happen. And thank you to yours truly for some of the audio fidelity we goosed up for this episode too. Big thanks to VideoFest's Founder Bart Weiss, the VideoFest team including Kelly Kitchens (who is also a Patreon supporter), Reid Robinson, Elijah Cruz Barron, Janeth Farnsworth, Jessica Spawn, Andy Streitfeld and Mark Wickersham as well as Barak Epstein of the Texas Theatre and Erin Barros of Concord Hospitality. More big thanks to Ernie Kovacs and Edie Adams archivist Ben Model for the tip to bring up the Ernie in Kovacsland book on stage prior to the interview as well. And now, here's Fred Armisen. Take a listen. Everyone has a story.
Send us a textIn this episode of The Lifestyle MD, Dr. Angela interviews Dr. Jim Walter, PhD—founder of the Institute for Preservation of Health and an expert in cardiovascular exercise physiology. Dr. Walter shares insights from more than a decade of research on how meaningful health benefits can come from integrating small, intentional movements into daily life—without relying on traditional exercise routines.Together, they explore the science behind “move more moments,” how incremental movement compares to structured exercise, and practical ways to re-engineer everyday activities for better long-term health. Dr. Walter also reflects on his personal motivation, shaped by the early loss of his father to heart disease, and how it continues to influence his work today.Listeners are invited to share their own “move more moments” and connect with Dr. Walter at https://www.jimwalterspeaks.com, by email at jim@jimwalterspeaks.com, or on Instagram @jimwalterspeaks.00:00 Introduction and Guest Welcome00:59 Dr. Jim Walter's Background and Passion01:46 The Importance of Movement Over Exercise03:57 Practical Tips for Integrating Movement07:14 Personal Stories and Motivation11:51 Re-engineering Daily Routines19:29 Tracking Progress and Staying MotivatedSupport the showFollow me on Instagram @angelalifestylemd and don't forget to SUBSCRIBE to my podcast & SHARE this episode.
In this Best Of from 2025, Mark sits down with Kenneth Milligan, M.D., Orthopedic Surgeon, and Eric Krohn, D.O., Pediatric Orthopedic Surgeon at Monument Health Orthopedic & Specialty Hospital in Rapid City while they share their vision in starting the Hip Preservation Institute. Typically only available in larger metropolitan areas, the Hip Preservation Institutes team brings much needed and highly specialized hip care to the Black Hills and the surrounding region with the goal of preventing long-term hip deterioration to patients through early intervention, monitoring and minimally-invasive surgery, when required. Hosted on Acast. See acast.com/privacy for more information.
Amy Rutherford on Smooths, Bred-By Success and Preservation Breeding [caption id="attachment_14897" align="alignleft" width="961"] Amy Rutherford winning Best Bred By Exhibitor at AKC National Championship with Wager.[/caption] Today's episode brings you a rare conversation with someone who does not say yes to interviews very often. Amy Rutherford joined host Laura Reeves for a holiday visit and the timing could not be better, fresh off her Best Bred-By Exhibitor win at the AKC National Championship with her Smooth Fox Terrier, Wager. For breeders, exhibitors, and dog show fans, this conversation delivers real insight into what it takes to build a program that lasts. From a childhood dog show moment to a lifetime in terriers [caption id="attachment_14896" align="alignleft" width="356"] Rutherford with one of her foundation Smooth Fox Terriers.[/caption] Amy's path started early. Her parents were horse people who also kept Australian Shepherds before they were AKC recognized. A winter trip turned into a defining moment when the family got snowed in and visited an AKC dog show. From the stands, young Amy watched Smooth Fox Terriers in the ring and knew she wanted that life. The journey was not immediate. Her first breed was Airedales, which taught hard lessons about grooming, structure, and realistic expectations. Eventually, she saved money and purchased Smooth Fox Terrier puppies that both finished quickly and became group winners. That early success did more than build confidence. It created a foundation and one of those early bitches still anchors the pedigree behind her dogs today. The handler apprenticeship that built a career Amy's handling career developed the way the best ones often do, through years of real work. She spent summers helping professionals and then committed to a full apprenticeship with Eddie and Leslie Boyes. She stayed for nine years, learning the daily realities of conditioning, presentation, animal husbandry, trimming and the logistics that define show life. [caption id="attachment_14894" align="alignright" width="278"] Rutherford showing Dover, Ch. Aimhi Type Cast, at Westminster Kennel Club.[/caption] That apprenticeship is a major takeaway for anyone interested in becoming a professional handler. Amy explains that experience builds skill and it builds a network. When she went out on her own, she had the credibility and connections that make the difference between surviving and thriving. Showing different breeds and winning with controversial dogs One of the most valuable parts of this episode is Amy's honest discussion about stepping into breeds that are not part of your original comfort zone. She moved from Smooth Fox [caption id="attachment_14898" align="alignleft" width="396"] Rutherford showing Standard Poodle, Dino, GCH. Del Zarzoso Salvame From Afterglow[/caption] Terriers into coated breeds including a Portugese Water Dog and a Standard Poodle import....
In this video I discuss critical Second Amendment case up for reconsideration after a prior 8-1 denial!
December 28, 2025 Jesus’ life of suffering and persecution began as an infant. Matthew records that Jesus fulfilled the Old Testament prophecies regarding the Messiah. If we follow Christ, we also must be obedient during times of suffering. Scripture: Matthew 2:13-23
We're continuing our look back at some of the most important For the People segments of 2025 and we'll start with: Preservation Connecticut - which turned 50 this year. Tune in and check out how they're going to continue sustaining and preserving critical buildings, sites, even social and cultural practices that helped shape the state we live in. Then we'll replay our visit with the Women's Mentoring Network. This nonprofit serving Fairfield County and beyond, is providing foundational skills for individuals to secure better employment options and encouraging individuals to seek educational opportunities as they look to become economically empowered. And we'll close replaying our introduction of Art Pharmacy - an organization becoming active in Connecticut enabling personalized social prescribing services with healthcare, university, corporate, and government partners to address the nation's most intractable health challenges.
In this video I discuss critical Second Amendment case up for reconsideration after a prior 8-1 denial!
Atheism & The Preservation of Iman In The Subcontinent! I Shaykh Muhammad Sägib Iqbäl
Monday Systematic and expository Bible Study for 22nd Dec 2025 at the Deeper Life Bible church Gbagada Lagos.
Como evitar a “ceia do arrependimento”? Separe trinta minutinhos do seu dia e descubra, com a Mila Massuda, como acontecem as infecções e intoxicações alimentares e quais cuidados fazem toda a diferença nas festas.Apresentação: Mila Massuda (@milamassuda)Roteiro: Mila Massuda (@milamassuda) e Emilio Garcia (@emilioblablalogia)Revisão de Roteiro: Vee Almeida e Caio de Santis (@caiodesantis) Técnico de Gravação: Caio de Santis (@caiodesantis)Editora: Angélica Peixoto (@angewlique)Mixagem e Masterização: Caio de Santis (@caiodesantis) Produção: Prof. Vítor Soares (@profvitorsoares), Matheus Herédia (@Matheus_Heredia), BláBláLogia (@blablalogia), Caio de Santis (@caiodesantis) e Biologia em Meia Hora (@biologiaemmeiahora)Gravado e editado nos estúdios TocaCast, do grupo Tocalivros (@tocalivros)REFERÊNCIASAL-MAMUN, M. et al. Food Poisoning and Intoxication: A Global Leading Concern for Human Health. Food Safety and Preservation, p. 307–352, 2018.
Plus, foldables may be getting more square, and Waymos act odd during a power outage.Starring Tom Merritt and Robb Dunewood.Show notes can be found here. Hosted on Acast. See acast.com/privacy for more information.
Trait Thompson, the executive director of the Oklahoma Historical Society, shares his journey from a finance background to a fulfilling career in public service. He discusses the importance of competition, the influence of music and history, and the challenges of preserving our digital footprint. The conversation also touches on the significance of Route 66, the art of barbecue, and the innovative approaches being taken in museums to engage the next generation.Trait Thompson:https://www.okhistory.orghttps://www.instagram.com/okhistoryhttps://www.instagram.com/traitthompsonMaverick Podcast:
Feliks Banel's guests on this LIVE BROADCAST of CASCADE OF HISTORY include Moira Nadal of the Washington Trust for Historic Preservation with this year's winners of Sivinski Preservation Grants; Derek Nguyen of the Washington State Historical Society in Tacoma with details about this year's model train exhibit; Malcolm Crockett of Crofton, BC on the history of that Vancouver Island community and his new book; Kerry Tymchuk, Executive Director of the Oregon Historical Society on this year's holiday exhibit of Meier & Frank department store Santaland decor and a look ahead at next year's Highway 101 centennial exhibit; lost & found sound from World War II with Chris Byrd, who hears his father Clifford Byrd - a B-17 gunner - on a recording from a radio show broadcast from London on Christmas Day 1943. More info about the Washington Trust for Historic Preservation Sivinski Fund: https://preservewa.org/programs/grants/valerie-sivinski-fund/ More info about the Washington State History Museum Model Train Show: https://www.washingtonhistory.org/exhibit/trainfestival-29/ More info Malcolm Crockett's book about growing up in Crofton, BC; https://www.barnesandnoble.com/w/no-backup-a-setup-and-more-malcolm-crockett/1148702514 More info about Oregon Historical Society's Meier & Frank Santaland: https://www.ohs.org/museum/exhibits/meier-and-frank-santaland.cfm Links to more information about most topics discussed on the show are available at the CASCADE OF HISTORY Facebook page: www.facebook.com/groups/cascadeofhistory This LIVE broadcast of CASCADE OF HISTORY was originally presented at 8pm Pacific Time on Sunday, December 21, 2025 via SPACE 101.1 FM and gallantly streaming live via www.space101fm.org from historic Magnuson Park - formerly Sand Point Naval Air Station - on the shores of Lake Washington in Seattle. Subscribe to the CASCADE OF HISTORY podcast via most podcast platforms and never miss regular weekly episodes of Sunday night broadcasts as well as frequent bonus episodes.
This conversation delves into the mysteries of ancient Peru, focusing on the recent DNA test results of a 2,000-year-old elongated skull from Paracas. The discussion explores the significance of knowledge over material wealth in ancient cultures, the architectural marvels of Peru, and the ongoing struggle to preserve archaeological sites against looting and neglect. The guest, Raul, shares his passion for documenting unexcavated sites and the challenges faced in preserving Peru's rich cultural heritage. The conversation also touches on the impact of new discoveries on traditional narratives in archaeology. In this conversation, the speakers delve into the complexities of archaeology, emphasizing the importance of evidence, the role of technology, and the need to challenge traditional narratives. They discuss the financial barriers to exploration and the value of indigenous knowledge in uncovering historical truths. The conversation highlights the ongoing quest for understanding our past and the collaborative efforts required to preserve and explore archaeological sites.Raul's website: pillarsofthepast.com
In episode 52 of Wake Up to Wealth, Brandon Brittingham interviews Jeff Hiatt, as they explore the ins and outs of cost segregation studies, explaining how property owners can accelerate depreciation and maximize their tax deductions.Tune in to gain a deeper understanding of investing and financial strategies that can change your perspective on wealth. SOCIAL MEDIA LINKSBrandon BrittinghamInstagram: https://www.instagram.com/mailboxmoneyb/Facebook: https://www.facebook.com/brandon.brittingham.1/ Jeff HiattInstagram: https://www.instagram.com/depreciationdoctor/?hl=enLinkedIn: https://www.linkedin.com/in/jeffreydhiatt/ WEBSITESBrandon Brittingham: https://www.brandonsbrain.org/home==========================SUPPORT OUR SPONSORS:Accruity: partner.accruity.com/brandon-brittinghamRocketly: https://rocketly.ai/
Frank & Lindsey Carriera break down the complex effort to preserve the Mirasol, a 100 year old landmark on Davis Islands, and explain why restoring historic buildings is far more complicated than new construction. They discuss storm damage, resiliency challenges, community feedback, and the long process of adapting an aging structure to modern needs without losing its character. This episode explores how preservation, economics, and neighborhood concerns intersect as Tampa continues to grow.0:00:00 - Intro0:06:03 - Mirasol's History0:11:17 - Redevelopment0:37:53 - Mirasol Restaurant0:43:46 - Community0:58:22 - Preservation 1:07:18 - Outro
This week on Motherhood Intended, Jacqueline closes out Season 6 with a meaningful re-air of one of the earliest and most impactful episodes from Season 1: “Egg Preservation: A Story of 10 Maybe Babies.”This episode intentionally follows last week's solo conversation about freezing your eggs and fertility timelines — and serves as a bridge into what's coming next.In this episode, Jacqueline chats with Alison, who shares her personal experience choosing to freeze her eggs. Alison walks through what the egg freezing process actually looked like, what she felt emotionally along the way, and what it meant to preserve her fertility and create options for her future — not guarantees, but possibilities.This re-air also marks the end of a season that looked different. Jacqueline reflects on balancing motherhood, work, and growth; learning new systems; building Your Fertility Village; and embracing the idea that there is power in the pause.And this story doesn't end here.When Season 7 begins, Alison will return to share where her egg-freezing journey from three years ago ultimately led her — offering listeners a rare, full-circle update.Whether you're considering egg freezing, supporting someone who is, or simply trying to understand your fertility options, this episode offers an honest, real-life perspective that continues to resonate.What's Coming Up• Season 7 premieres on January 8, 2026• Your Fertility Village officially launches in the new year • Founding members can join now for $7/month, locked in for life • An in-person gathering is coming in January — follow along to stay updated!Support the show__________________________________________________________________________________
Creating Timeless Elegance: How Woodson & Rummerfield Bring Hollywood Regency into the 21st Century. From celebrity estates to curated collectibles, Jamie Rummerfield and Ron Woodson share their philosophy on bold, elevated design, preservation of iconic architecture, and the art of collaboration in Los Angeles. Designer Resources Pacific Sales Kitchen and Home. Where excellence meets expertise. Design Hardware – A stunning and vast collection of jewelry for the home! TimberTech – Real wood beauty without the upkeep To celebrate this episode of the Convo By Design Icon Registry, Christine Anderson sits down with Jamie Rummerfield and Ron Woodson of Woodson & Rummerfield House of Design. The duo discuss their signature approach to interiors—melding the opulence of old Hollywood with sleek modern sensibilities for a discerning clientele. They share stories from celebrity projects, the thrill of collecting one-of-a-kind pieces, and the lessons learned from running a showroom on La Cienega. Jamie and Ron also discuss their nonprofit foundation, CA Projects, dedicated to preserving Southern California's iconic architecture, emphasizing the importance of heritage in contemporary design. Show Topics & Segment Outline: Introduction & Guest Backgrounds Christine introduces Jamie Rummerfield and Ron Woodson. Overview of their design style: Hollywood opulence meets modern refinement. Design Philosophy & Influences Hollywood Regency roots and modern adaptations. Influence of Los Angeles history, old Hollywood cinema, and personal family heritage. Fashion-forward client expectations and balancing boldness with timelessness. Collaboration & Partnership How Jamie and Ron complement each other creatively. Problem-solving, brainstorming, and the synergy of their partnership. Career Highlights & Notable Projects Celebrity estates and high-profile commissions (without naming clients). Influence of their La Cienega showroom as a “three-dimensional calling card.” Philosophy on sourcing rare furniture, art, and collectibles. Preservation & Advocacy Founding of CA Projects to save iconic Southern California architecture. Importance of protecting historically significant homes and estates. Public involvement and future plans for the foundation. Personal Passions & Lifestyle Weekend hobbies, travel, research, and inspiration. How personal passions inform design work. Future Plans & Product Development Upcoming secret projects and product lines. Speaking engagements and experiential presentations for design communities. Closing Remarks How to connect with Jamie and Ron: WanderDesign.com, Instagram @WanderDesign. Preview of CA Projects website: SIAPROJECTS.com. Invitation for designers and architects to share projects with Convo By Design. This wraps up another episode of the Convo By Design Icon Registry. A celebration and recognition of a true master in the art of design and the mastery of all that encompasses in the pursuit of making better the lives of those they serve. And, giving back along the way. Thank you Jaime and Ron for your many years of friendship, partnership and collaboration. This was the first time we met and the episode was hosted by Christine Anderson, I miss her. Thanks for listening to Convo By Design. Thank you to my partner sponsors, Pacific Sales Kitchen and Home for presenting the Convo By Design Icon Registry and Convo By Design partner sponsors, TimberTech and Design Hardware. And thank you for taking the time to listen. I couldn't do this without you, wouldn't want to. I hope this show helps you stay motivated, inspired and focused so you can rise above the chaos. – CXD
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What happens after the shot matters just as much as the hunt itself.In this episode of Delta Waterfowl's Voice of the Duck Hunter, Joel Brice sits down with Blake Robbins, a graduate student in meat science at Oklahoma State University, and Dr. Morgan Pfeiffer, professor of Animal & Food Sciences, to break down best practices for caring for waterfowl meat from field to table.Whether you're a new hunter chasing sustainable, natural food or a seasoned waterfowler looking to improve meat quality, this conversation covers: -Proper meat care after the hunt -Common mistakes that ruin duck and goose meat -Preservation techniques between cleaning and cooking -How science meets tradition in wild game nutritionIf you care about honoring the bird, the hunt, and the meal that follows — this episode is for you.Website and Social Media Links:Delta Waterfowl: https://deltawaterfowl.orgFacebook: /DeltaFans/Instagram: https://www.instagram.com/deltawaterfowl/Twitter: https://twitter.com/DeltaWaterfowl/Delta Waterfowl: https://deltawaterfowl.org Facebook: https://www.facebook.com/DeltaFans/ Instagram: https://www.instagram.com/deltawaterfowl/Twitter: https://twitter.com/DeltaWaterfowl/
Some Oklahomans are looking at an increase in their health insurance premiums.A new partnership hopes to preserve the Choctaw language.Solar power enthusiasts remain optimistic despite a cut in federal incentives.You can find the KOSU Daily wherever you get your podcasts, you can also subscribe, rate us and leave a comment.You can keep up to date on all the latest news throughout the day at KOSU.org and make sure to follow us on Facebook, Tik Tok and Instagram at KOSU Radio.This is The KOSU Daily, Oklahoma news, every weekday.
Today – A major preservation effort is moving forward in Shelby, thanks to a $130,000 grant that could help save one of Ohio’s oldest mausoleums.Support the show: https://richlandsource.com/membersSee omnystudio.com/listener for privacy information.
In this video I discuss critical Second Amendment case up for reconsideration after a prior 8-1 denial! Check out AOR by going to: https://bit.ly/ARMEDSCHOLARUse my code ARMEDSCHOLAR and receive $50 off your individual sign-up fee or $25 of your family plan sign-up fee
Utah Auditor Tina Cannon has pulled her lawsuit challenging the meeting on the vote to relocate her office in Utah's Capitol... Greg and Holly get the latest details from KSL NewsRadio's Adam Small on where this office debate stands and why the lawsuit was dropped.
In this video I discuss critical Second Amendment case up for reconsideration after a prior 8-1 denial! Check out AOR by going to: https://bit.ly/ARMEDSCHOLARUse my code ARMEDSCHOLAR and receive $50 off your individual sign-up fee or $25 of your family plan sign-up fee
A group of lawmakers and state leaders have voted to kick the Utah State Auditor out of her current office in the Capitol. A meeting was abruptly called today to vote on the removal, and we’ve learned that Utah’s state auditor has filed a lawsuit challenging these attempts. Greg and Holly break down the latest.
Ep 162: Dec 10, 2025 - Whose Body Preservation Tubes Are These? Linda is working on a new episode for next week. Please enjoy this special rebroadcast! New medical study finds Gun deaths Rising Sharply in Children NASA and Space X to launch new “Psyche” mission https://Nasa.gov/nasatv mission to Psyche metal asteroid, 144 miles long, 173 miles long made up of gold, platinum and other precious metals worth trillions of dollars Interview with experience “Wana Lawson” “they wanted to take a sub-creature and evolve it” “putting their genes into a human fetus” Interview with “Brian” from Minnesota “I was in a tube…I saw two beings” “very tall, very skinny, stark white” “almost like they were clones” “I thought there albinos” “silver, kind of bluish, greyish silver” Betty Andreasson Luca “the balance of nature is in jeopardy” “greys are remote imaging sensors” “what if …humans are remote imaging servants?” “Our universe is paired to another one” “Time flows to the past” “..our souls return back here” ==== Books Mentioned: Glimpses of Other Realities Volume 1: Fact and Eyewitnesses By Linda Moulton Howe ==== ==== Upcoming Appearances: Conscious Life Expo 2026 February 20th-23rd, 2026 https://consciouslifeexpo.com/linda-moulton-howe-2026/?ref=njyynty ==== #LindaMoultonHowe #Earthfiles — For more incredible science stories, Real X-Files, environmental stories and so much more. Please visit my site https://www.earthfiles.com — Be sure to subscribe to this Earthfiles Channel the official channel for Linda Moulton Howe https://www.youtube.com/Earthfiles. — To stay up to date on everything Earthfiles, follow me on FaceBook@EarthfilesNews and Twitter @Earthfiles. To purchase books and merchandise from Linda Moulton Howe, be sure to only shop at my official Earthfiles store at https://www.earthfiles.com/earthfiles-shop/ — Countdown Clock Piano Music: Ashot Danielyan, Composer: https://www.pond5.com/stock-music/100990900/emotional-piano-melancholic-drama.html
Guests Dr. Andrea Necchi, Dr. Ashish Kamat and host Dr. Davide Soldato discuss JCO article "End Points for the Next-Generation Bladder-Sparing Perioperative Trials for Patients With Muscle-Invasive Bladder Cancer," focusing on the evolving treatment landscape of MIBC (muscle-invasive bladder cancer) and the need to properly design novel trials investigating non-operative management while including the incorporation of biomarkers and patient perspectives in clinical trials. TRANSCRIPT The disclosures for guests on this podcast can be found in the show notes. Dr. Davide Soldato: Hello and welcome to JCO After Hours, the podcast where we sit down with authors from some of the latest articles published in the Journal of Clinical Oncology. I am your host, Dr. Davide Soldato, medical oncologist at Ospedale San Martino in Genoa, Italy. Today we are joined by JCO authors Andrea Necchi, Associate Professor of Medical Oncology at University San Raffaele and Medical Oncology at Ospedale San Raffaele in Milan, Italy, and Ashish Kamat, Professor of Urologic Oncology and Cancer Research at University of Texas MD Anderson Cancer Center. Both Professor Necchi and Professor Kamat are internationally recognized experts in the field of genitourinary malignancy and particularly in bladder cancer. Today we will be discussing the article titled "Endpoints for the Next Generation Bladder-Sparing Perioperative Trials for Patients with Muscle-Invasive Bladder Cancer." So thank you for speaking with us, Professor Necchi and Professor Kamat. Dr. Andrea Necchi: Thank you, Davide, and thank you JCO for the opportunity. Dr. Ashish Kamat: Yeah, absolutely. It is a great honor and privilege to be discussing this very important article with you. So thank you for the invitation. Dr. Davide Soldato: The article that you just published in JCO reports the results of a consensus meeting that was held among experts in the field of genitourinary malignancy and particularly for bladder cancer. So the objective was really to define endpoints for a novel generation of trials among patients diagnosed with muscle-invasive bladder cancer. So my first question would be: what is the change in clinical practice and in clinical evidence that we have right now that prompted the start of such consensus in 2025? Dr. Andrea Necchi: So, we are living so many changes in the treatment paradigm of patients with muscle-invasive bladder cancer. In general, patients diagnosed with bladder cancer or urothelial cancer today, thanks to the advent of immunotherapy or immunotherapy combinations, and today thanks to the advent of novel antibody-drug conjugates like enfortumab vedotin in combination with immunotherapy that are actually changing the landscape of treatment of patients with metastatic disease and also are entering quite fast into the treatment paradigm of patients with organ-confined disease with a lot of clinical trials testing these combination therapies, neoadjuvantly or adjuvantly, before or after radical cystectomy. Having said that, by potentiating the efficacy of systemic therapy, an increasing number of patients that receive neoadjuvant therapy of any kind, at a certain point in time, result to have achieved a deep response to systemic therapy, evaluated radiologically with conventional imaging, CT scan or MRI, or with cystoscopy or with other urology-based techniques, urinary cytology, and so. And based on the fact that they achieve a complete response, so no residual viable disease after systemic therapy, they raise concern about the fact that they have to undergo surgery like radical cystectomy that is quite impactful for their quality of life and for the future of their lives after the surgery. So the point that the patients are raising, and the patients are raising this point, is primarily due to the efficacy of systemic therapy. And we have seen so many cases fortunately achieving a deep response. So the question about what to do with the patient that at a certain point, at the start with the commitment to radical cystectomy, but at a certain point in time change their mind towards something else if possible, depending on the fact that they have achieved a deep response, is something that is a question and is a need to which we have to provide data, information, and guidance in general to the patients. Dr. Davide Soldato: If we look at the population that the recommendations were formulated for, we are mainly speaking about patients who would be fit for cystectomy, and this is a very distinct population compared to those who are not fit for cystectomy, both from a medical oncology point of view but also from a urologic point of view in terms of surgery. So, can you explain a little bit to our listeners why you think that this distinction is critical and why you developed this recommendation especially for this population? Dr. Ashish Kamat: That is a very important distinction that you made. To build upon what Professor Necchi mentioned earlier, this question that we get from patients after neoadjuvant therapy or systemic therapy is not a new question. It has been something that they have been asking us for the last 20 or 30 years. "Do I really need to have my bladder taken out?" And patients who are especially not fit for surgery will sometimes say, "Do I need to have my bladder taken out? And if I cannot have my bladder taken out, am I going to just not have anything done?" Because the eligibility for radical cystectomy is also a moving target. Over the years with improvement in surgical technique, improvement in perioperative therapy, ERAS protocols, et cetera, it is really unusual for us to deny a patient the opportunity to have major surgery unless clearly they have very significant comorbid conditions. So I think this endeavor is more broadly encompassing of the patient population than what was evident in previous years. And I really want to give a shout out to Professor Necchi because what we did was, as part of the International Bladder Cancer Group and Professor Necchi is an integral part of the scientific advisory board, we broached this topic broadly during one of our discussions. And of course, Andrea always does this, he picks on a topic and then he says, "Okay, we need to discuss this really in detail," put together a multinational, multicenter collaborative group, but the driving force was our patients. Because our patients are constantly asking, "Do I need to lose my organ? Do I need to have radiation therapy?" which again, also, has a lot of side effects. So this was really to answer the question in today's day and age as to do we need to do local consolidation, and if so, in what way? It is not a new question, but we have newer therapies, newer technology, and better ways to answer this. So it is a much needed question that needs to be answered. And I think the distinction between non-surgical candidates and surgical candidates is a little bit blurred in today's day and age. Dr. Davide Soldato: What about the eligibility, for example, for cisplatin-based chemotherapy? Because I think that that is a very fundamental part of this type of strategy that we apply to patients with muscle-invasive bladder cancer. So we know that there are some caveats for proposing such treatment. And also this population was specifically defined inside this recommendation. Dr. Andrea Necchi: I think that the focus of our work is just to analyze what is happening after any type of systemic therapy the patient may get neoadjuvantly. So it is not actually a question of treatment eligibility or including cisplatin eligibility. This is an old question of today's practice and clinical trials. But regardless of what the patient received neoadjuvantly, the point that we have addressed in our consensus meeting was what to do next as a further step after systemic therapy or not. So basically we are- the consensus guidance includes all-comers, so patients to get any type of systemic therapy. So really non-selected based on specific features that determine a special eligibility to a special or a particular therapy. But an all-comer approach is always the winning approach for the translation to be in practice, an all-comer approach just focusing on what has happened after treatment and that we are assessing by the use of conventional imaging, MRI or CT, cystoscopy, urinary cytology, and trying to merge all together this information, all these features in a unique, shared, reliable definition of clinical complete response that could be used as a biomarker for the selection of newer therapies instead of pathological response that has been historically used, and maybe surrogate for the outcome, the long-term outcome and survival of these patients. Dr. Davide Soldato: A very specific point of the consensus was actually the definition of clinical complete response. As you were saying, this is actually a combination of several parameters including urinary cytology, the use of cross-sectional imaging, for example CT scan, but also the evaluation in cystoscopy of the bladder. Do you foresee any potential problems when applying this type of recommendation, not inside clinical trials, but in the context of routine clinical practice? Dr. Ashish Kamat: Absolutely. And that was the whole reason we had this consensus meeting. What happens nowadays in daily practice, and we see this every day at our center, we see patients referred to us. This definition or this sort of attempt to define clinical complete response is an ongoing issue. And urologists, medical oncologists, radiation oncologists are always looking to see, does my patient have a complete response? That definition and those paradigms have changed and evolved over the years. The FDA had a workshop many years ago looking at this very question. And it was to address the proposal that complete clinical response, which is a clinical definition, a clinical state, does this correlate with pathologic response? And with the technology and the systemic therapies we had then, the answer was 'no'. In fact, more patients got recurrent disease than did not get recurrent disease. And that is why, of course in the paper we mention the trials that looked at this question, the trials that evolved around this question. And I think the distinction between a clinical trial and daily practice is extremely important when we are looking at this definition per se. Because essentially what happens with this issue is that if the patient is not appropriately counseled, and if the physician does not do the appropriate clinical complete response assessment as Professor Necchi mentioned, right, cystoscopy, cytology, imaging, use of markers that are still in evolvement, we risk doing harm to the patient. So we caution in the paper too that this definition is not ready for prime time use. It is something that needs to be studied. It is a rigorous definition and currently we are recommending it for clinical trials. I am sure eventually it will trickle down into clinical practice, but that guidance was not the purpose of this consensus meeting. Dr. Davide Soldato: There are several parameters that are potentially evolving and could potentially enter inside of clinical practice. For example, you mentioned pelvic MRI and we have now very specific criteria, the VI-RADS criteria, we're able actually to diagnose and also to provide information. So along with these novel imaging techniques, we also know that there are novel biomarkers that could be explored, for example ctDNA and urinary DNA. So what I was wondering is, why were not these included inside the definition that you provide for clinical complete response? And do you think that, as we are designing these trials to potentially spare cystectomy for this patient, we should include these biomarkers very early so that we can actually provide better stratification for our patients and really propose this type of cystectomy-sparing strategy only to those where we are very confident that we have obtained a clinical complete response? Dr. Andrea Necchi: I would say you have just to wait. So a follow-up is ongoing and hard work is ongoing. At the time we met, at the time we established the meeting in mid-December last year, we had no information on the ctDNA data from major trials, with only a few exceptions. So we were just at the beginning of a story that was more than likely to change but still without numbers and without data from clinical trials. Now in just nine months or 10 months time, we have accumulated important data and newer data will be presented during just a few weeks and a few days regarding the ctDNA, circulating tumor DNA in particular, as a prognostic marker assessed baseline or assessed after neoadjuvant therapy. So the point is certainly well made and ctDNA is certainly well shaped to be incorporated in a future definition of clinical complete response. But you have to consider the fact that most of the data that we are accumulating related to ctDNA are about the post-cystectomy field or the metastatic field. So regarding neoadjuvant therapy, you know, we have neoadjuvant therapy in the context of bladder-sparing approach, basically we have no information. And the point that is emerging in our daily practice when using these biomarkers or in clinical trials, and the impression in general, is that it is a very strong biomarker associated with survival, but we absolutely do not know what is the performance of the test in the prediction of superficial bladder relapses, high-grade pTa relapse in the bladder that is left untouched in the patient. We are considering, and maybe it will be just a matter of further discussion, not just what is happening within the immediate endpoint of clinical CR, but also what is happening later with other survival endpoints. And for example, when looking at the type of events that we may see in this kind of bladder-sparing approaches, most of the events, also in the trials that have been published including the RETAIN study published in JCO, most of the events are related to superficial high-grade superficial non-muscle invasive relapses. So the ability to predict these types of events with ctDNA is completely unknown. Maybe, maybe other liquid biomarkers like urinary tumor DNA, utDNA, could be a bit better shaped in the prediction of this kind of events, you know. But we have still to build the story. So the question is good. The answer is yes, we will likely, more than likely incorporate liquid biomarkers in the definition, but we have to wait at least more data and more robust data in order to translate this information in routine practice, you know. Another consensus meeting is organized by IBCG and the same folks for November. This meeting will be primarily focused on the liquid biomarkers, the interpretation and use and approval and so of liquid biomarkers including bladder cancer. And we will likely be able to address all these, most of these open issues, so most of these points in the next meetings. Dr. Davide Soldato: In the consensus you say that probably clinical complete response is now ready to be included in early phase trials, so actually to test what is the efficacy of the regimens that is being evaluated inside of these trials. But you actually do very in-depth work of defining what are the most appropriate endpoints for later phase trials. So to be very specific, the phase three registrational trials that bring new regimens inside of this space. So I just wanted to hear a little bit about what was the definition for event-free survival, which you define as the most appropriate one for this type of trials. And as you were mentioning before, Professor Necchi, there is a very specific interest on the type of events that we observe, especially when we look at these superficial relapses inside of the bladder. So was this a very urgent matter of debate as we define which type of events should actually trigger event-free survival? And did you make a very thoughtful decision about why using this type of endpoint instead of others, for example metastasis-free survival? Dr. Ashish Kamat: Yeah, this was a matter of intense debate as you might imagine. And again, this is a moving target. So as Professor Necchi mentioned, we tend to partner with each other, our organizations, on having definitions of clinical complete response, biomarker, retreats, and then using that as a marker, and you might imagine this definition of what is appropriate event-free survival, what events matter to the patient, is something we have been talking about for two years. It was not just something that came up at the retreat. But at the retreat there was intense discussion. One of the things that we talked about was bladder-intact event-free survival because we are trying to spare the patient's bladder. And do we count bladder-intact event-free survival as something that is relevant? The patient advocates absolutely liked that, right? They wanted that. But then we also learned from some of the studies, for example from the RETAIN study, that the non-muscle invasive recurrences can actually lead to metastatic disease. It is not as benign when you have a patient with muscle-invasive bladder cancer that then develops a non-invasive tumor because maybe there is cancer growing underneath the surface that we don't detect when we look in the bladder. So a lot of those discussions were held, debated. It was a consensus. I have to say it was not 100% agreement on that particular definition, but it was broad consensus. And Andrea, do you want to clarify a little bit as to how we came about that consensus? Because I think this is a very important point we need to make. Dr. Andrea Necchi: We focused on a bit different definition of BI-EFS, Bladder-Intact Event-Free survival. Just stating EFS as an all-inclusive parameter including all type of high-grade relapse or progression or death that may happen to the patient. So that we were counting high-grade pTa, pT1, CIS relapses to the bladder and of course more deeper involvement in the muscle layer and so, and metastatic disease as a relapse. But the point is that as compared to the classical bladder-intact EFS definition of chemoradiation bladder-sparing approaches that is including muscle-invasive relapses only or death as events, we tried to be as inclusive as possible in order to be as much conservative as possible and to raise as higher the bar as possible for the success. And this is actually what the patients are asking us. So they are asking, "Okay, I can save my bladder, sparing radical cystectomy, but at which cost?" So in order to provide an answer, we have to be very, very cautious and be on the right shape, on the right position to say, "Okay, we have accomplished the most, the safest points, you know, by which you can proceed with the bladder-sparing." This is the first point. The other point is related to the MFS, metastasis-free survival that you have mentioned. For sure, it was recognized as a very important point for sure. But in the discussion was clear that our focus was in saving patients, curing the patient, and saving the bladder. Any single event, superficial event that may occur in the bladder-saving approaches of this kind may expose the patient to an extra risk of developing distant metastases, as it happened for example in the RETAIN study. So EFS defined as we have agreed and published, is actually a way of including or anticipating in a safest position the MFS. Because most or if not the entirety of the events of metastasis development in patients undergoing bladder-sparing after neoadjuvant systemic therapy were preceded by a superficial phase of disease relapse, you know. So I remember very, very few, or we can count just on the finger of one hand, the cases that have been reported in the literature developing de novo metastatic disease in the similar bladder-sparing approaches, in particular when using a maintenance immunotherapy strategy, you know, after they reach TURBT. So this is the reason why with all the limitation that Ashish has mentioned, with all the uncertainties that are still there, the nervousness that is still there, EFS, as defined in the protocol, as put in the paper, is to us at the moment is the safest way to use a primary endpoint in potentially registration trials of this kind with perioperative systemic therapy and response-adapted surgery. Dr. Ashish Kamat: And David, just to be absolutely clear for our listeners, right, so what was the event-free survival that we defined? Essentially it was a very inclusive definition. Event was defined as high-grade tumor persistence, recurrence, or progression during or after perioperative therapy, and receipt of any additional standard of care treatment including radical cystectomy, radiotherapy or even intravesical therapy. So this was done at the behest of our patient advocates because we really wanted to make a very robust definition that could be utilized appropriately as an adequate primary endpoint for both early and late phase bladder preservation trials. Dr. Davide Soldato: I think that it really highlights one of the points that I liked the most about this consensus is that it really incorporated the patient vision and a sort of shared decision making process when we are deciding how we want to design these trials that will explore this bladder-sparing surgery. And Professor Necchi mentioned something that I think will be also a very interesting question for trials that will be developed considering the activity of this combination that we are seeing right now, which is maintenance. Because right now our approach in the few cases where patients do not do any type of treatments after an induction with neoadjuvant treatments is basically represented by observation. So I was wondering if you think that the field will actually evolve to a sort of maintenance strategy even in patients that will achieve a complete clinical response? Dr. Andrea Necchi: We just mentioned briefly in the paper, this is a very important point that was touched during the discussion, and in particular was raised and discussed by FDA people participating in the meeting. And when looking at the data from the trials that were available and are still available thus far, we could provide a suggestion that maintenance immune therapy is the preferred approach in this kind of approach as it currently stands, as the data currently stand. Because the cleanest data towards the successful part of this journey is related to the studies that provided a kind of maintenance therapy, like the study with nivolumab or the RETAIN-2 study with maintenance immune therapy instead of RETAIN study that was just stopping treatment until surgery with MVAC chemotherapy. So in general the impression is that maintenance therapy may help in reducing the type of events, including the events that we incorporate in the EFS definition that we mentioned in the paper. The point that you mentioned is very important because on the other side we have a problem, a big problem of affordability and cost of the treatment. The de-escalation trials are an urgent need and represent a call for the studies. Unfortunately, as you mentioned, this is something that moves beyond the possibilities of this type of consensus because we don't have data and we have to accumulate data from clinical trials prior to saying, "Okay, certain patients could de-escalate therapy and stop therapy and some other not." So we are still at the very beginning. So we can do- we can discuss about this in the radical cystectomy paradigm but not in the bladder-sparing paradigm, you know. But this is for sure a point, a discussion point that will be taken, pretty well taken in one year or two year projection. Dr. Davide Soldato: I was wondering if in the consensus, considering that patient advocates and patient associations were also involved, did you decide to actually suggest the inclusion of patient-reported outcomes or the evaluation of shared decision-making in the development of this trial really as endpoints that should matter as much or as much as possible as event-free survival and clinical complete response? Dr. Ashish Kamat: Oh yeah, absolutely. We had patient advocates, we had the World Bladder Cancer Patient Coalition, Bladder Cancer Advocacy Network, patient representatives. And we always consider this. Shared decision-making is actually the impetus behind why these efforts have been launched, right? So it is the shared decision-making that is very, very important. It is the driving force behind what we do. And it is worth noting, for example, for the design of such studies, regulatory agencies consider response-based endpoints or overall survival as primary endpoints. But the patient advocates consider quality of life to be just as important, if not more important sometimes than overall survival numbers. Because patient advocates will say, "Well if I live longer but I'm miserable living longer, yes that works for regulatory agencies but doesn't work for us." So PROs clearly are very, very important. And, in fact, we just literally had a meeting in Houston, the IBCG meeting where PROs were a main point of what we discussed. So incorporating PROs in everything we do, not just this but everything we do, Dr. Necchi, myself, everybody involved in these fields realizes it is very, very important. So absolutely. Dr. Davide Soldato: I want to thank again Professor Necchi and Professor Kamat for joining us today. Dr. Andrea Necchi: Thank you. Dr. Ashish Kamat: It is our pleasure. Dr. Davide Soldato: Thanks again and we appreciate you sharing more on your JCO article titled "Endpoints for the Next Generation Bladder-Sparing Perioperative Trials for Patients with Muscle-Invasive Bladder Cancer." If you enjoy our show, please leave us a rating and review and be sure to come back for another episode. You can find all ASCO shows at asco.org/podcast. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
Send us a message!Join us as we finish out Kelsier's POV of the Mistborn trilogy. We laugh, we cry, we curse Will's name. It's a great time! Music is by Alexander Nakarada.Support the show
About the Show:"We are wired for storytelling. It's why we love movies and books and YouTube and all these kinds of things, because we all love stories, and we connect to them in some way." – Angie AlbrightIn this episode of I Am Northwest Arkansas®, host Randy Wilburn sits down with Angie Albright, director of the Shiloh Museum of Ozark History in Springdale.Angie's path from an Iowa farm to leading one of Northwest Arkansas's oldest museums tells its own story about what draws people to this region. Under her leadership, the Shiloh Museum has become more than a repository of artifacts—it's a living community space where the past meets the present, and where everyone's story matters.The museum brings Ozark history to life through school field trips, heritage preservation projects, and welcoming spaces like "The Front Porch" that invite people in. Angie talks about how they decide what stories to tell, why collecting diverse voices is essential, and how they're evolving to serve Northwest Arkansas's changing population.Whether you've lived here for generations or just arrived, the Shiloh Museum offers a way to understand the threads that connect us all—and why this place feels like home to so many.Key Takeaways:The Shiloh Museum is a living, evolving community space, not just a place for “old things.”Connecting with history helps both kids and adults see how the region—and their own families—fits into the bigger story of the Ozarks.The museum covers six Arkansas counties and partners with schools to open history's doors to over 20,000 students each year.They are working to include the stories of all communities, including Spanish-speaking, Marshallese, and African American residents, through events and collecting oral histories, photos, and artifacts.Preservation and innovation go hand-in-hand—from saving old log cabins to making exhibits accessible in many languages.Most museums only display a fraction of their collection; digitization gives the public more access to stories and artifacts than ever before.You are welcome at the Shiloh Museum—there's always something new to learn, and it's always free to visit!The upcoming U.S. 250th anniversary (in 2026) will be a time for the whole community to reflect on our shared journey and future.All this and more on this episode of the I Am Northwest Arkansas® podcast.Important Links and Mentions on the Show*Shiloh Museum of Ozark History – Website: shilohmuseum.orgVisit in person! 118 W. Johnson Ave, Springdale, AR 72764 (Open Monday–Saturday, 10am–5pm, always free!)Shiloh Museum on InstagramShiloh Museum on FacebookShiloh Museum Online Collections Database: Collections PortalFront Porch Project: community-built outdoor gathering space at the museumOzark Voices Project: collecting and sharing diverse community storiesCrystal Bridges Museum of American ArtFayetteville Public Library's genealogy collection
I interviewed Avinash Changa about The Institute of Immersive Perservation on Tuesday, November 18, 2025 at IDFA DocLab in Amsterdam, Netherlands. This is a listener-supported podcast through the Voices of VR Patreon. Music: Fatality
Send us a textConclusion of our series, Restoring What Is Broken. G-d encourages us to celebrate, renew our commitment to biblical practices, and to guard against the strategies of hell to derail us.
Northwest Bible Church – Dec. 7, 2025 – Matthew – Alan Conner Matthew 5:13-16 Salt and light Intro A. THE SALT OF THE EARTH (Matthew 5:13). The uses of salt. a. add flavor to food. Job 6:6; Col. 4:6. b. preservation. Numb. 18:19; 2 Chron. 13:5. c. purification. Lev. 2:13; Ezek. 43:24; Ex. 30:35. How do Christians function as salt. a. by holy living and proclaiming the gospel of the kingdom. b. promoting godly values. Prov. 14:34. B. BAD SALT AS A PICTURE OF AN APOSTATE. Tasteless salt. Not the saved who loses salvation. 1 Jn. 3:9; 2:19 Good for nothing. Lk. 14:34-35 trampled under foot by men. Conclusion
The world around us has transformed dramatically—but has philanthropy kept up? For our Finding Brave guest today, John Studzinski, American-British investor and humanitarian and the author of the new book A Talent for Giving: Creating a More Generous Society that Benefits Everyone, this question isn't academic—it's deeply personal. His philanthropic journey began humbly, volunteering at a soup kitchen as a teenager. Today, he's recognized globally for transformative work addressing homelessness through London's Passage Day Centre and championing emerging artists through the Genesis Foundation. In the U.S., he serves on the boards of The J. Paul Getty Trust, St. Patrick's Cathedral, and the Foundation for Art and Preservation in Embassies (FAPE) and is a member of the Council on Foreign Relations. In this inspiring conversation, John shares his views on how the true meaning of philanthropy has been lost and how it needs to transform to inspire the next generation to make a more meaningful impact. John tells us about his book and how it has helped inspire individuals to spend the gift of time serving the common good. From the power and importance of human connection to the essential need for empathy, John shares the critical lessons he hopes readers will take from his book. We discuss why giving is not very beneficial unless we understand how, at the same time, to receive. John walks us through how he manages his time in order to be of service to his communities the way he does. John goes on to explain what he believes would happen to humanity if people stopped giving and caring about the community. And he teaches us that so much of our dignity is dependent on what we've given instead of what we've spent or kept. If you have the desire to contribute in new ways and give of your talents and abilities to support the common good, this conversation will inspire you to action. Every person on this planet has authority that can be used for the common good, and leveraging those strengths and talents for the benefit of our communities is not only rewarding but deeply instrumental and meaningful. Key Highlights From This Episode: A bit about John's book, A Talent for Giving, and how it's a call to action to serve the common good with your talents. [04:48] How John's faith inspires him to give to the community, and why he always tries to put himself in another person's shoes. [12:47] John discusses how he stewards his time and manages to do everything that he does throughout the day. [16:27] Why empathy is a critical piece in giving, how John wants everyone to read his book, and the most important thing to learn from it. [18:23] The concept of shame, setting boundaries around giving, and how giving is only beneficial if you can receive. [24:30] What would happen in the world if everybody stopped caring about the common good and giving back. [28:55] John tells us about his process of dictating his book and which chapter surprised him the most. [33:30] The first place listeners can start if they want to give back to their community today. [38:23] For More Information: John Studzinski on LinkedIn Links Mentioned in Today's Episode: John's book, A Talent for Giving: Creating a More Generous Society that Benefits Everyone John's book on Audible Genesis Foundation Genesis Foundation on Instagram Genesis Foundation on Facebook Genesis Foundation on X PIMCO ——————— GOT A BURNING CAREER OR PROFESSIONAL GROWTH QUESTION? Ask me on Hubble! I'm thrilled to join the Hubble advisory group, a space for thoughtful conversations and honest advice on life, work, business, and career challenges. I often hear from people worldwide seeking guidance on careers, leadership, personal growth, and making a bigger impact. Now, connecting and answering your questions is easier than ever—Hubble lets you book a one-off call or recurring sessions with me. I help with: Career, leadership, and executive coaching Communication and relationship skills training Personal branding and thought leadership strategy Women's leadership growth and advancement Keynote speaking and workshops on confidence and self-trust growth, visibility, thriving through uncertain times, and making a positive impact You'll also learn how to recognize and close the 7 damaging confidence gaps that block thousands of professionals from reaching their highest and most rewarding potential. Book some time with me here on Hubble - I'd love to support your top goals: https://app.hubble.social/kathycaprino ——————— Order Kathy's book The Most Powerful You today! In Australia and New Zealand, click here to order, elsewhere outside North America, click here, and in the UK, click here. If you enjoy the book, we'd so appreciate your giving it a positive rating and review on Amazon! And check out Kathy's digital companion course The Most Powerful You, to help you close the 7 most damaging power gaps in the most effective way possible. Kathy's Power Gaps Survey, Support To Build Your LinkedIn Profile To Great Success & Other Free Resources Kathy's TEDx Talk, Time To Brave Up & Free Career Path Self-Assessment Kathy's Amazing Career Project video training course & 6 Dominant Action Styles Quiz ——————— Sponsor Highlight I'm thrilled that both Audible.com and Amazon Music are sponsors of Finding Brave! Take advantage of their great special offers and free trials today! Audible Offer Amazon Music Offer Quotes: "The multiplier effect of giving is much more powerful than people realize." — John Studzinski [0:10:09] "Your greatest gift from God that you have is actually not your talent, but it's actually your time. You don't know how many days you have left on the planet." — John Studzinski [0:14:59] "If you're not empathetic, it's like having your eyes closed and your ears covered. – It's like putting a bag over your head and not trying to engage." — John Studzinski [0:19:25] "If someone asks you for money, I always say, 'Tell them you'll donate your time, and if they don't want your time, you don't want them because they don't appreciate you as a human being.'" — John Studzinski [0:25:47] "Giving is not very beneficial unless you understand how, at the same time, to receive." — John Studzinski [0:27:04] "We are very, very dependent on each other. Perhaps more so than we realize." — John Studzinski [0:30:19] Watch our Finding Brave episodes on YouTube! Don't forget – you can experience each Finding Brave episode in both audio and video formats! Check out new and recent episodes on my YouTube channel at YouTube.com/kathycaprino. And please leave us a comment and a thumbs up if you like the show!
Historically Thinking: Conversations about historical knowledge and how we achieve it
The Greek philosopher Plato is famous for writing his teachings in the form of dialogues. But there are additionally a series of seven letters attributed to Plato. Over the centuries much ink has been spilt in arguments over their authenticity. My guest today argues that these letters are actually epistolary philosophical novel which are if nothing else a “ripping great yarn”.“In the pages of Plato's letters,” writes Ariel Helfer, “we find Plato the teacher, the counselor, the ally, the statesman; intrigue and faction in the court of a tyrant; grand political hopes dashed as famous utopian dreams become living nightmares—it is a stunningly dramatic and dynamic portrait of Plato and his philosophy.” An alll this is set in the exotic setting of Hellenized Sicily during the 5th century BC, which has a cultural and political complexity that makes the head spin uncontrollably. Ariel Helfer is Associate Professor of Philosophy at Wayne State University, and the most recently editor and translator of Plato's letters in an edition titled Plato's Letters: The Political Challenges of the Philosophic LIfe . He was last on Historically Thinking to discuss Plato's dialogue Alcibiades, and the broader subject of political ambition, in a conversation that was published on September 30, 2020.For show notes, resources, and our archive, go the Historically Thinking Substack ChaptersIntroduction and Background — 00:22The Authenticity Debate of Plato's Letters — 03:25Arguments for Authenticity and Unity — 11:27Textual History and Preservation — 18:36Historical Context: Plato in Syracuse — 26:19Themes in the Letters — 33:55Letter One: A Dramatic Opening — 40:51Letter Six: Philosophy, Law, and Playfulness — 47:35Philosophy vs. History: Different Perspectives — 56:24The Herculaneum Scrolls and Future Discoveries — 1:03:20
With the longest coastline in the continental U.S. and 825 miles of warm beaches, Florida has a lot of shoreline to protect. That's where Pepper Uchino comes in. As president of the Florida Shore & Beach Preservation Association, he leads the state's only organization devoted entirely to safeguarding the coastlines that make Florida so special. And with beach and waterfront activities among the most popular draws for out-of-state visitors, the state's natural beauty isn't just scenic – it's essential to our economy. In this episode, SMPR President Heidi Otway talks with Pepper about his unexpected path into environmental advocacy and why investing in the next generation of coastal engineers may be the key to preserving Florida's future.
In this episode, Darin sits down with BioHarvest CEO Ilan Sobel, a leader who is redefining the future of plant compounds, human performance, and scalable biotech. Ilan shares the extraordinary origin story of BioHarvest's technology, how a single scientific breakthrough is disrupting global supply chains, and why "democratizing the power of the plant kingdom" has become his life mission. From hydration to longevity molecules to the French Paradox, Ilan reveals how his company is transforming ancient wisdom into modern, clinically validated solutions that can reach the masses. What You'll Learn 00:00:00 Welcome and Introduction 00:00:32 Sponsor: Thera Sage 00:02:10 Introducing Ilan Sobel (Bio Harvest Sciences) 00:03:37 Electrolyte Solution Powered by Circulation 00:04:37 Vinia's Baseline: Sea Salt, Coconut Water, Marine Magnesium 00:05:36 The Uniqueness of Pi-Seed Resveratrol 00:06:50 Solubility and Bioavailability: Lasting 12 Hours 00:08:48 Overview of Botanical Synthesis Technology and Cell Growth 00:13:58 Vinia's Potency: 1,000 Red Grapes in a Capsule 00:15:31 Why Blood Flow is Critical for Longevity 00:17:23 Increased Blood Flow to the Brain and Mental Alertness 00:19:00 Sponsor: Our Place Cookware 00:21:35 The Abuse of Nature and the Need for Preservation 00:24:15 Overcoming Pharma's Barriers: Consistency, Low Levels, and Patents 00:28:32 Vinia as a Validation of the Technology's Power 00:30:02 Scaling Production: 137 Bioreactors 00:32:21 Scaling Comparison: Manhattan Island's Worth of Resveratrol 00:34:26 Clinical Substantiation and Solubility 00:35:14 The Mechanism: Increasing Nitric Oxide and Reducing ET-1 00:38:33 The "Vinia Difference" - When Consumers Feel the Benefits 00:40:05 Unseen Benefits: Reducing Oxidative Damage 00:41:16 Low Churn Rate and Science-Backed Commitment 00:42:52 Sponsor: Manna Vitality 00:44:46 Commitment to Mission and Customer Reviews as Fuel 00:48:01 Support for First Responders and Veterans 00:51:32 Ilan's Journey to CEO and Unlocking the Gold Mine 00:55:37 The Plan to Build a Second 100-Ton Facility 00:57:12 Democratization and Scaling: Software Economics in Biotech 01:00:21 The French Paradox and Red Wine Connection 01:01:33 Next in DTC: Olive Cells and Forbascoside for Liver Health 01:05:36 New Partnership: Creating a Super Saffron for Cognitive Health 01:13:02 Partnership with Tate & Lyle for Non-Nutritive Sweeteners 01:16:11 The Movement of Change and Legacy for Future Generations 01:18:52 Introducing the Vinia Blood Flow Hydration Stick Packs Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Our Place: Toxic-free, durable cookware that supports healthy cooking. Go to their website at fromourplace.com/darin and get 35% off sitewide in their largest sale of the year. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Ilan Sobel Website: bioharvest.com Instagram: @ilansobel Red Grape Cell Product: vinia.com Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway "Democratizing the plant kingdom isn't just a business strategy — it's a responsibility. If science gives us the ability to help millions of people feel better, perform better, and live longer, then we have an obligation to scale it in a way the whole world can access."
Bonus | Adoptees for Family Preservation Full Show Notes and Transcript Here Join our adoptee community on Patreon here Check out our upcoming live events here! Find out more about Adoptees for Family Preservation here! Support Haley's new podcast here! This podcast is for educational and entertainment purposes only. Nothing stated on it, either by its hosts or any guests, is to be construed as psychological, medical or legal advice. Please seek out professionals in those fields if you need those services. The views expressed by the hosts of Adoptees On or any guests are their own and do not represent the opinions of any organization or other person unless otherwise stated.
In 2022, IDEAS explored how the brutal strategy called "urbicide" — the intentional killing of a city — is used in war to destroy residents' sense of home and belonging. This podcast revisits the original story and includes a brief update from architect Ammar Azzouz. Since the collapse of the Assad regime last year, he has returned to Homs, Syria, twice. He tells IDEAS he has mixed emotions being home again.*This episode is part of our series, The Idea of Home.It originally aired on June 16, 2022.Guests in this podcast:Ammar Azzouz is an architectural critic and analyst at Arup, as well as a research associate at the University of Oxford. His most recent book is Domicide: Architecture, War and the Destruction of Home in Syria. Nasser Rabbat is a professor and the director of the Aga Khan Program for Islamic Architecture at MIT. He has published numerous articles and several books on topics ranging from Mamluk architecture to Antique Syria, 19th century Cairo, Orientalism, and urbicide.Marwa Al-Sabouni is a Syrian architect based in Homs and the author of The Battle for Home: The Vision of a Young Architect in Syria and Building for Hope: Towards an Architecture of Belonging.Hiba Bou Akar is an assistant professor in the Urban Planning program at Columbia Graduate School of Architecture, Planning and Preservation. She is the author of For the War Yet to Come: Planning Beirut's Frontiers.Nada Moumtaz is an assistant professor in the Department of Study of Religion and Near and Middle Eastern Civilizations at the University of Toronto. She trained and worked as an architect in Beirut, Lebanon, and is the author of God's Property: Islam, Charity, and the Modern State.
Emily Utt has one of the most unique jobs within the Church: she spends her days inside its most sacred and historic spaces. Sometimes that means slipping on a hard hat; other times it means uncovering stories and artifacts that deepen our understanding of the faith's heritage. In this episode, Emily shares what she's learned from a career spent safeguarding holy places—and why these spaces should matter to each of us. 1:43- What Constitutes a Sacred Space? 4:49- Remembering and Connection 9:55- We are Them 16:40- A Very Cool Job 19:09- Principles of Preservation 24:47- Appropriateness and Real People 27:22- Why Spend Time in Sacred Spaces? 31:33- Kirtland Temple 37:46- Until You've Been in Their Home 44:21- Looking Forward and Looking Back 50:07- What Does It Mean To Be All In the Gospel of Jesus Christ? "I imagine every person in the world has a place that would be their waters of Mormon and how beautiful is that place, for there they came to know God." Links: Follow Him podcast with Emily- https://podcasts.apple.com/us/podcast/followhim/id1545433056?i=100070927727 Hi Five Live with Emily- https://www.youtube.com/watch?v=xy1wPXog1q8
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