The Joe Cohen Show

Joe sits down with Christian Drapeau, a stem cell expert with over 20 years of research under his belt, to talk about how the body repairs itself, and how we can help it do a better job. They get into what stem cells actually do, why we lose them as we age, and how that affects recovery, energy, and long-term health. Christian shares simple, natural ways to support stem cell activity, like fasting, exercise, and plant-based supplements. They also talk about stem cell therapies and how they compare to everyday strategies you can use to support your body's natural repair system.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/Timestamps: (00:00) Introduction to the Joe Cohen Show(00:17) Meet Christian Drapeau(01:14) Understanding Stem Cells and Their Benefits(02:00) Natural Ways to Increase Stem Cells(06:44) Stem Cells and Longevity(12:19) Stem Cell Supplements vs. Injections(23:42) Hyperbaric Chambers and Stem Cells(25:32) Understanding Hyperbaric Chambers(26:45) Introduction to Stem Cell Enhancing Plants(27:13) Top Plants for Increasing Stem Cells(28:00) Mechanisms and Effects of Specific Plants(32:45) Combining Plants for Optimal Stem Cell Release(34:35) Active Compounds in Stem Cell Enhancing Plants(41:59) Stem Cell Supplements and Their Benefits(46:08) Conclusion and Further Resources

In this episode of The Joe Cohen Show, Joe takes a personal and scientific look at monogamy, exploring why some people feel more content in exclusive relationships than others. He breaks down what research says about the hormone vasopressin and its role in bonding, loyalty, and long-term attachment, drawing from both animal studies and genetic findings. Joe also shares a surprising result from his own supplement routine, where taking L-arginine and glycine seemed to shift his natural tendencies toward greater monogamy. It's a unique mix of biohacking, hormones, and human behavior you won't want to miss.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ Timestamps:(00:00) Introduction to the Joe Cohen Show(00:16) Exploring Monogamy and Personal Tendencies(02:56) The Role of Vasopressin in Monogamy(05:44) Vasopressin's Impact on Human Relationships(14:14) Personal Experiment with Supplements(22:42) Conclusion and Recommendations

In this special episode, Joe sits down with health coach and SelfDecode Pro user Joline Schaaphok to walk through her personalized health insights using genetic data. They explore everything from supplement recommendations and food sensitivities to overlooked risk factors like anemia and cardiovascular health. It's a real-time example of how genetic reports, labs, and lifestyle data can work together to uncover actionable insights. Whether you're a practitioner, a biohacker, or just curious about precision health, this live analysis offers a behind-the-scenes look at how to turn data into meaningful change.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ Timestamps:(00:00) Introduction to the Joe Cohen Show(00:16) Meet Joline Schaaphok(02:02) Diving into Joline's Genetic Results(03:32) Macronutrient and Vitamin Recommendations(04:41) Food Sensitivities and Allergies(05:46) Health Overview Report: Genetic and Lifestyle Insights(09:27) Supplement Recommendations and Customization(23:29) Refining the Supplement List(24:08) Optimizing the Daily Regimen(25:29) Detailed Regimen Breakdown(28:15) Advanced Filtering Techniques(33:11) Addressing Anemia and Food Allergies(39:17) Comprehensive Lab Testing(40:50) Genetic Insights and Recommendations(43:10) Final Thoughts and Next Steps

In this episode of the Joe Cohen Show, host Joe Cohen discusses the power of biohacking and precision health with Sasha Powell, a nurse practitioner and integrative healthcare provider. Sasha shares her experience using DNA data to optimize her patients' health outcomes, focusing on areas like hormone and weight management, mental health, and overall well-being. They dive into the specifics of how genetic insights can personalize treatment plans, leading to better, faster results. Whether it's diagnosing mental health issues more accurately or managing physical health conditions like diabetes and inflammation, Sasha highlights the transformative impact of personalized medicine. Tune in to understand why integrating genetic information into healthcare is not just an innovation but a necessity.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ Timestamp:(00:00) - Introduction to the Joe Cohen Show(00:16) - Meet Sasha Powell(00:56) - Using DNA for Personalized Health Solutions(01:24) - Weight and Hormone Management Strategies(03:11) - Blood Sugar Regulation and Diet Recommendations(07:25) - Mental Health and Genetic Insights(10:59) - The Role of Neurochemistry in Treatment Plans(13:48) - Personalized Supplement Recommendations(30:10) - The Importance of Methylation in Health(34:03) - Utilizing Self Decode for Comprehensive Health Management(38:31) - Optimizing Quality of Life(39:06) - Longevity Screener Insights(39:34) - Clinical Overview Report(40:30) - Health Overview Report(41:44) - Lab Data and Clinical Recommendations(45:15) - Family Planning and Genetic Risks(45:57) - Integrating Lab Tests and Genetic Data(48:44) - Using SelfDecode in Clinical Practice(58:56) - The Future of Healthcare with AI(01:04:26) - Organic Acids Test and Lab Considerations(01:08:08) - Concluding Thoughts and Recommendations

In this solo episode, Joe Cohen explores the powerful effects of glutamate on the brain and how elevated levels can drive anxiety, obsessive thoughts, and overstimulation. He shares insights from personal experiments with supplements like AKG, proline, and arginine and explains how they impacted his mental state, motivation, and focus.Joe also breaks down the symptoms tied to excess glutamate, from headaches and insomnia to mood swings and neurological issues. He discusses why certain people are more sensitive to glutamate due to genetic differences, and outlines what's helped him manage it, including specific doses of NAC, glycine, B6, vitamin C, and more.This episode offers a practical, firsthand look at how glutamate functions, what throws it out of balance, and what can be done to bring it under control.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ Timestamps:(00:00) - Introduction(00:16) - Understanding Glutamate and Its Effects(04:32) - Personal Experiments with Glutamate(08:22) - Supplements and Strategies to Lower Glutamate(18:31) - Symptoms and Conditions Related to High Glutamate(20:20) - Genetic Factors and Glutamate(22:13) - Conclusion

In this eye-opening episode of The Joe Cohen Show, Joe sits down with microbiologist and biotech entrepreneur Kiran Krishnan to dismantle the myths and marketing hype surrounding microbiome testing. Drawing parallels between the DNA and microbiome industries, they expose the scientific shortcuts, technological flaws, and misleading health claims being sold to consumers.Krishnan, the mind behind one of the few microbiome platforms used in published research, breaks down what a legitimate test looks like and why most tests on the market fall short, sometimes by as much as 70% in accuracy. The conversation also explores probiotics in depth, why strain specificity matters, and how consumers can make more informed decisions when navigating this complex and evolving space.Whether you're a health professional or someone trying to optimize your gut, this episode will help you separate science from sales.

Most genetic testing companies promise personalized health insights, but their reports barely scratch the surface, often analyzing just a handful of genetic variants. In this episode, Joe Cohen shares what happened when the SelfDecode team took a close look at dozens of these reports to understand how and why they fall short and what it actually takes to do it right.He shares how SelfDecode analyzes hundreds of thousands (sometimes millions) of variants per report, uses advanced technology to generate more accurate results, and integrates labs and lifestyle data to deliver truly actionable recommendations. If you've ever wondered whether your DNA test was worth the money, this episode is a must-listen.- Check out the SelfDecode Report Shop: https://selfdecode.com/shop/- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ (00:00) - Introduction(00:16) - Overview of Genetic Reports(01:26) - Competitor Analysis and 100X Series(02:34) - Detailed Breakdown of Genetic Reports(03:27) - Recreating Competitor Reports(08:57) - Final Thoughts

In this episode, Joe Cohen talks with Mark Notton, founder of Revive DNA, about how your DNA can shape your sleep, energy, and long-term health.After helping his wife recover from a chronic autoimmune condition using a personalized nutrition approach, Mark left his executive career at Samsung to launch a health tech company.Now, Revive DNA is making science-backed, DNA-driven wellness accessible to more people with support from major institutions and powered by OmicsEdge technology.Tune in for a deep dive into the future of personalized health and what most programs are still getting wrong.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ Timestamps:(00:00) - Introduction(00:16) - Meet Mark Noten: Founder of Revive DNA(01:06) - Mark's Journey into the Health Space(02:09) - A Personal Health Crisis: Mark's Wife's Story(04:40) - The Role of DNA in Health and Nutrition(06:44) - Revive DNA: Technology and Partnerships(11:53) - Revive DNA App: Features and Benefits(19:31) - Upcoming Sleep Study with Samsung(28:43) - Future Directions and Closing Remarks

In this episode, Joe discusses the benefits of the probiotic L. Plantarum, specifically the 299V strain. He talks about its effectiveness in reducing gas, improving mood, exercise recovery, and more. He shares how he personalizes his probiotic routine using SelfDecode, why the specific strain matters more than the brand, and how he takes higher doses to really feel a difference. If you're dealing with gut issues or just want to understand how probiotics can affect things like immunity, allergies, mood, or even homocysteine levels, there's a lot in here you'll find useful.Tune in to learn more about optimizing your health with probiotics and get personalized recommendations from SelfDecode.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ Timestamps:(00:00) - Introduction(00:16) - Discussing L. Plantarum and Probiotic Recommendations(01:28) - Joe's Personal Experiences with Probiotics(05:28) - Benefits of L. Plantarum(07:43) - Research and Evidence on L. Plantarum(09:56) - L. Plantarum's Impact on Various Health Conditions(12:01) - Probiotics and Skin Health(13:56) - Probiotics and Metabolic Health(18:56) - Final Thoughts and Recommendations

Join Joe Cohen in this insightful episode as he interviews Martin Kremmer, CEO and co-founder of BioWatch and FreeAge. Martin, a pioneer in the Danish biohacking scene, shares his company's innovative approach to DNA and epigenetic testing to develop personalized longevity plans. They discuss the importance of combining different types of data, the future of functional health, and the role of stress management in achieving optimal health. Martin also introduces the Copenhagen Health Week and emphasizes the significance of simple lifestyle changes for long-term health. Don't miss this comprehensive talk on biohacking, health tech, and much more.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ 

Is Bryan Johnson's anti-aging regimen the ultimate blueprint for health, or just another one-size-fits-all approach? In this episode, Joe Cohen breaks down Johnson's protocol, highlighting what works, what doesn't, and why personalization is key.Joe shares his own experiences and expert insights to help you optimize your health on your own terms.- Discover the pros and cons of Bryan Johnson's approach- Why personalization matters more than a strict regimen- The best practices for sleep, nutrition, and longevityJoin us for a deep dive into the science behind health optimization!- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ Timestamps:(00:20) - Brian Johnson's Blueprint: An Overview(00:48) - Personalization in Health Protocols(01:04) - Sleep and Eating Habits(03:31) - Critique of Calorie Restriction(05:10) - Protein Intake and Muscle Building(08:20) - Skepticism on Brian Johnson's Regimen(15:50) - Supplement Analysis: Ingredients and Dosages(25:31) - Joe's Personal Supplement Routine(28:21) - Blueprint Product Reviews(32:43) - Evaluating Niacin and B Vitamins(34:21) - Zinc, Selenium, and Genetic Predispositions(35:21) - Personal Dosage Preferences(37:03) - Critique of Supplement Formulas(37:42) - Advanced Supplements and Personal Experiences(54:50) - Dietary Choices and Sensitivities(57:29) - Exercise and Lifestyle Recommendations

In this episode, Joe Cohen sits down with Dr. Brigitte Hanly, CEO, Chief Scientist, and co-founder of Stemaid Institute, to explore the cutting-edge world of stem cell therapy. They discuss how pluripotent stem cells and exosomes can optimize health, repair injuries, and even slow aging. Joe shares his firsthand experience with the treatments, including their impact on immune function, brain health, and inflammation. Plus, they dive into the ethics of stem cell research and the future of regenerative medicine. If you're curious about biohacking, longevity, and the science behind cellular rejuvenation, this is an episode you don't want to miss!- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ 

Can a single probiotic strain transform your gut, lower cholesterol, and even help with food sensitivities?In this episode of The Joe Cohen Show, we dive into the fascinating research behind Lactobacillus reuteri. Joe shares his personal experiments and breaks down the science on how L. reuteri may support digestion, reduce inflammation, and even impact weight and skin health. Should you add this probiotic to your regimen? Tune in to find out!- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ 

Dr. Elena Gross joins Joe Cohen to share her journey from debilitating chronic migraines to becoming a neuroscience researcher and entrepreneur. They explore the role of mitochondrial dysfunction in migraines, how ketosis can optimize brain energy, and the importance of personalized health approaches. Joe and Elena break down the science behind oxidative stress, genetic risk factors, and key nutrients that support migraine management. Tune in for expert insights on biohacking migraines and optimizing your brain health!- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ Timestamps:(04:41) - Ketosis and Heavy Metal Poisoning(06:18) - Mitochondrial Dysfunction and Migraines(07:27) - The Role of Neurotransmitters and Inflammation(10:27) - Energy Deficiency and Brain Function(22:04) - Genetic Factors and Environmental Triggers(24:37) - Managing Migraines in Today's World(36:25) - Understanding Migraine Triggers(36:48) - Genetic Factors and Pathways(37:28) - Migraine Diary and Identifying Triggers(38:12) - Hormonal and Metabolic Influences(38:31) - Nutritional Supplements and Ketone Bodies(39:25) - Clinical Trials and Research Insights(41:32) - Personal Experiences with Treatments(42:01) - Alternative Therapies and Lifestyle Changes(48:28) - Genetic Testing and Personalized Medicine(57:15) - Mitochondrial Function and Chronic Conditions

In this episode of The Joe Cohen Show, Joe shares his honest review of the Genova NutrEval FMV amino acids test.He discusses the challenges of interpreting the results, the differences between urine and blood samples, and key insights related to antioxidant support, mitochondrial function, and nutrient needs.Considering the NutrEval test? This episode offers a detailed look at what to expect and important factors to consider.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/ 

What if a simple technique could break down mental barriers, eliminate stress, and unlock peak performance? Meet Brad Yates, the legendary "EFT Wizard," whose tapping techniques have transformed millions of lives. In this episode, Joe sits down with Brad to reveal how Emotional Freedom Techniques (EFT) can help you clear emotional blocks, optimize your mindset, and take control of your well-being. Whether you're an entrepreneur, athlete, or just someone looking to elevate your life—this episode gives you an interesting and new approach to unshakable confidence, success, and inner peace.- Check out SelfDecode: https://selfdecode.com/l- Join Joe's online community: https://thejoecohenshow.com/

Are you curious about the science behind GLP-1 agonists like Ozempic? Want to know how you can naturally support weight loss and blood sugar regulation without relying on medication?In this episode of The Joe Cohen Show, we dive deep into the world of GLP-1, exploring natural alternatives that can help suppress hunger, enhance metabolism, and optimize your health. From cutting-edge supplements to simple lifestyle tweaks, this episode is packed with actionable insights.Tune in now to discover:What GLP-1 agonists do and why they're trendingThe truth about their role in weight loss and diabetes managementNatural ways to stimulate GLP-1 for better health- Check out SelfDecode: https://selfdecode.com/- Buy Jo's Resistant Starch: https://amzn.to/41V6gPH- Join Joe's online community: https://thejoecohenshow.com/ 

Is the genetics industry full of BS? Joe Cohen sits down with Dr. Puya Yazdi, co-founder of SelfDecode, to expose the real science behind genetic testing, polygenic risk scores, and why most DNA reports are giving you half-truths (or worse—total garbage).If you care about your health, longevity, and actually understanding what your genes say about you, this episode is a must-listen. Buckle up—this one's a game-changer.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

In this episode of The Joe Cohen Show, Joe dives into the world of probiotics and biohacking with a deep dive into Lactobacillus fermentum. He shares his personal experience megadosing this unique probiotic, which has been linked to boosting glutathione levels—one of the body's most powerful antioxidants. Joe discusses the science behind L. fermentum, its potential benefits, and whether he's noticed any significant effects. Tune in to explore the latest in supplementation, self-experimentation, and cutting-edge health optimization!- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

In this episode of The Joe Cohen Show, we take a deep dive into genetic reports, specifically analyzing the Wild Health Report. Joe breaks down the strengths and weaknesses of these reports, highlighting the common pitfalls in genetic testing and how they often analyze only a limited set of variants. He also introduces a new and improved alternative: the 100X Wildly Healthy Functional DNA Report. Tune in to discover what makes a genetic report truly effective, how to interpret DNA-based diet and nutrition insights, and why a more comprehensive approach can revolutionize personalized health optimization. Don't miss this insightful discussion on the cutting edge of biohacking and functional medicine!- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

In this episode of The Joe Cohen Show, Joe explores the science of air purification and why investing in the right air purifiers and air filters is essential for optimizing health. He breaks down how poor indoor air quality—filled with mold spores, VOCs, and airborne pollutants—can impact energy levels, cognitive function, and inflammation. Joe shares his biohacking approach to selecting the most effective air filtration systems, including the latest technology for achieving cleaner air at home. If you're looking to upgrade your air quality, reduce toxins, and take control of your environment, this episode is for you.Buy the Air Purifiers:AZEUS UV Light Air Purifier on AmazonDAYETTE H14 Air Purifier on Amazon- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

Join host Joe Cohen as he sits down with biohacker, actress, and health influencer Melanie Avalon for an insightful discussion on women and biohacking.Melanie shares her top biohacks, secrets to boosting performance, and even some surprising drinking biohacks. As the host of multiple health-focused podcasts, founder of AvalonX, and author of What, When, Wine, Melanie brings a wealth of knowledge on intermittent fasting, paleo-style nutrition, and longevity strategies. Get 10% OFF on https://avalonx.us/ by using coupon code ‘JOE'- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

In this episode of Should You Take This?, host Joe Cohen dives deep into Lactobacillus rhamnosus GG (L. Rhamnosus GG)—one of the most researched probiotic strains for gut health, brain function, and heart health.Joe shares his megadosing experiment, where he took 375 billion CFU of L. Rhamnosus in one day—25x the standard dose—to test its effects on mood, cognition, digestion, and cardiovascular health. He breaks down the scientific research behind Lactobacillus rhamnosus, explaining how it can:✔ Reduce excess glutamate and increase GABA, leading to improved mood and mental clarity✔ Lower TMAO levels, a metabolite linked to heart disease risk✔ Strengthen the gut barrier, improving digestion and immune functionHe also explores the genetic link, explaining how SelfDecode flagged L. Rhamnosus as a top recommendation based on his unique DNA risks for neurotransmitter imbalance, inflammation, and metabolic health.If you're wondering whether Lactobacillus rhamnosus is the right probiotic for you, this episode breaks down the real-world benefits, genetic considerations, and optimal ways to take it.- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

In this episode of Should You Take This?, host Joe Cohen dives deep into one of his top three favorite probiotics—Bifidobacterium longum. If you've struggled with bloating, digestion issues, or simply want to optimize your gut health, this probiotic might be a game-changer.Joe shares his personal experience with B. longum, breaking down its effectiveness in reducing gas, improving digestion, and supporting overall health. He also explores the scientific research behind it, discussing its potential benefits for mood, immunity, and inflammation.Tune in to learn whether B. longum is the right probiotic for you and how it fits into Joe's biohacking regimen. Don't miss this insightful episode packed with actionable tips to enhance your well-being!- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

Join Joe Cohen in the second episode of the DNA Deceptions series, where he takes a hard look at the world of DNA and genetic testing. In this episode, Joe shares his unfiltered thoughts on 10x Genetics, explaining why he believes it's one of the worst products in the genetic testing market. From questionable marketing tactics to flawed science, this episode uncovers the truth behind the claims and sets the stage for a deeper exploration of the myths surrounding genetic testing. A must-listen for anyone seeking clarity in the confusing world of DNA-based health solutions!

In the first episode of the DNA Deception series, Joe Cohen takes a critical look at 3x4 Genetics and their functional approach to DNA testing. With an emphasis on the science and practical applications, Joe explains why this method often fails to meet expectations. Whether you're exploring DNA-based health solutions or simply curious about genetic testing, this episode offers valuable insights into the promises and pitfalls of functional genetics.

In this special "Best of Season 7" episode, we're revisiting the most impactful, inspiring, and thought-provoking moments from our standout interviews this season. From groundbreaking health hacks and personal growth strategies to expert insights on optimizing your life, these are the clips that sparked the biggest conversations. Whether you're a long-time listener or new to the show, this episode is packed with must-hear wisdom from our incredible guests. Tune in for a quick recap of what made Season 7 unforgettable! - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

In this episode Joe sits down with Jack Smith, known for his pioneering biohacking experiments. Jack shares his biohacking journey, highlighting unique health devices like the Pulse PEMF machine, EES cube, Altwork desk, and Oura Ring.  He also delves into therapies such as ketamine for mental wellness, GAINSWave, and resistant starch for gut health.  Through discussions on neurofeedback, silent retreats, and advanced wellness practices, Jack underscores his dedication to health optimization techniques and consistent lab testing. You can follow his ongoing experiments on X @_jacksmith Interested in joining the upcoming AIWO retreat? Click here to schedule a call. - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

In this episode, Aaron Michael and Dr. Saida Desilet discuss practical tips for enhancing intimacy, overcoming common sexual challenges, and sustaining long-term passion.  Gain insights from their combined 50 years of experience in revolutionizing sex coaching, relationships, and intimacy.  Learn about natural methods to boost sexual health, the impact of neurochemistry, and the role of emotional openness in sexual satisfaction.  Whether you're single, in a relationship, or looking to optimize your intimate experiences, this episode provides invaluable knowledge on creating dynamic and fulfilling connections. - Visit https://embodiedlove.love/ - Follow Dr. Saida Desilets on Instagram - Follow Aaron Michael on Instagram - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ Timestamps: 00:00 Introduction 01:09 Common Mistakes in Sexual Relationships 02:48 Health and Its Impact on Sex Drive 05:00 The Role of Neurochemistry in Sexual Health 06:21 Substances and Their Effects on Sexual Function 15:03 Techniques for Enhancing Sexual Experience 26:58 Emotional Connection and Sexual Openness 34:41 Healing from Trauma and Self-Discovery 35:46 Exploring Mental Arousal and Touch 39:33 Understanding Erotic Fingerprints 40:13 Preventing Boredom in Long-Term Relationships 41:19 The Dynamics of Sexual Desire 58:20 The Role of Smell in Attraction 01:00:51 Navigating Threesomes and Sexual Exploration

In this episode, Joe sits down with Chris Mirabile, founder and CEO of Novos Labs, to explore cutting-edge strategies for reducing your biological age and slowing the pace of aging.  Chris shares his personal journey and the science behind his success, diving into the mechanisms of aging and the powerful supplements that can make a difference.  They discuss the benefits of fisetin, glycine, hyaluronic acid, and more, uncovering how these ingredients contribute to longevity and overall health.  Chris also shares insights into his daily health regimen, the clinical trials backing Novos' products, and the innovative formulations that are paving the way for a longer, healthier life.  Tune in to discover how you can take control of your aging process and optimize your health with the latest in anti-aging science. - visit https://novoslabs.com/ - Follow Chris @slowmyage - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

In this episode, Dr. Maloof reveals her biohacking strategies to revolutionize your sex life, just as you would your nutrition and fitness. Discover research-backed practices and expert insights that go beyond the basics, helping you elevate your intimate experiences and achieve a healthier, more fulfilling life. As the founder and CEO of Adamo Bioscience, Molly is at the forefront of bringing modern sex education to couples with a groundbreaking intimacy program developed through a study of the science of love. The Adamo Method is a 9-week program meticulously crafted for couples ready to propel their relationship to extraordinary heights.  Developed by relationship and sexuality experts Dr. Saida Desilets and Aaron Michael, The Adamo Method distills over 48 years of wisdom in the realms of sex, love, and human connection. The Adamo Method has demonstrated statistically significant improvements in: Sexual Satisfaction: 86% of participants reported improvements. Sexual Communication: 79% of participants reported enhanced communication. Arousal: 73% of women reported improvements. Sexual Functioning: 67% of women reported enhancements. Orgasm Quality: 70.4% of women and 65.4% of men reported improved orgasm quality. Orgasm Frequency: 63% of women and 69.2% of men reported increased orgasm frequency. Reduction in Sexual Shame: Participants experienced a significant decrease in shame, promoting a healthier, more positive sexual self-image. Note: these percentages refers to individuals who completed the program, and do not represent improvements at a population level. Use code JOE10 and get 10% OFF Adamo - visit https://livingadamo.com/ - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

This episode was originally published on May 22, 2015. Join Joe in an engaging interview with Dr. Gerald Pollack, a distinguished professor from the University of Washington, as they explore the groundbreaking concept of EZ water, also known as the fourth phase of water.  Discover its unique properties, health benefits, and interaction with factors like infrared light, pressure, and minerals.  The discussion extends to structured water, grounding, and even delves into revolutionary theories such as Rupert Sheldrake's morphic resonance.  Tune in for an insightful journey into water science and its profound implications for biohacking and health optimization. - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

In this episode, Joe interviews Dr. Andrew Ahn, an internal medicine physician and expert in physiological signal analysis.  The central topic of discussion is Heart Rate Variability (HRV). Dr. Ahn describes various measures of HRV, including time-domain, frequency-domain, and nonlinear analysis. He shares insights into personal HRV tracking and the lifestyle factors that influence it, such as exercise, sleep, and stress.  The conversation delves into the effectiveness of wearable devices for HRV measurement and explores breathing techniques that can improve HRV.  Additionally, Joe and Dr. Ahn discuss the role of genetics in HRV and the potential benefits and challenges of personalized health optimization through data-driven approaches. - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

In this episode, Joe dives deep into the world of hair loss and hair growth treatments with Dr. Alan Bauman, a leading hair restoration physician.  With over 33,000 patients treated and 12,000 hair transplant procedures performed, Dr. Bauman shares his expertise on various treatments like PRP, FUE, Regenera, and even microneedling.  The discussion covers the effectiveness and applications of these therapies, including the potential and limitations of topical treatments like minoxidil and finasteride.  They also explore the impact of nutrition, lifestyle, and newer regenerative medicine techniques on maintaining and enhancing hair growth.  Joe brings his personal experiences and research into the conversation, seeking clarifications and insights from Dr. Bauman on how to optimize hair health. Timestamps:  (00:00) - Introduction (01:27) - Understanding PRP for Hair Loss (09:02) - Comparing Hair Loss Treatments: PRP, Minoxidil, and More (16:27) - Combining Treatments for Optimal Results (23:27) - The Role of Genetics and Mitochondrial Function in Hair Loss (26:43) - The Importance of Quality in Hair Growth Devices (33:05) - Topical Finasteride: Efficacy and Usage (40:16) - Microneedling: Benefits and Misconceptions (45:07) - Scalp Massaging and Therapeutic Treatments (47:00) - Ketoconazole Shampoo: Pros and Cons (50:28) - Essential Oils and Hair Loss (56:41) - Nutritional Factors in Hair Health (01:03:16) - Future of Hair Loss Treatments If you're interested in learning more about how your DNA and genetics affect your health: - Visit https://www.baumanmedical.com/ - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

In this third and final part of our series with Elizma Lambert, we dive deep into the world of biohacking, exploring the latest technology, supplements, and research. Join us as Elizma Lambert shares her expertise on optimizing both body and brain health, providing actionable tips and strategies for achieving peak performance. In this episode, you'll discover: The most effective biohacks for enhancing mental clarity and physical vitality. How to personalize your health regimen for maximum results. Cutting-edge research and resources for staying ahead in the health optimization game. Practical advice on integrating these biohacks into your daily routine. Whether you're a seasoned biohacker or just beginning your health optimization journey, this episode is packed with valuable insights and tips that you won't want to miss.  Tune in and take the next step toward optimizing your health with the expert guidance of Elizma Lambert. - visit elizmalambert.com - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

This is the second episode of a three-part series with Elizma Lambert, where we delve into the world of the Organic Acids Test (OAT) and its crucial role in optimizing health. In this episode, Elizma explores an array of biochemical markers, including yeast and fungal indicators, bacterial markers, oxalate metabolites, Candida overgrowth, thyroid function, and mitochondrial efficiency.  Lambert explains how these markers are integral to identifying gut dysbiosis, assessing mitochondrial performance, achieving holistic biochemical balance, and so much more. - Visit https://elizmalambert.com/ - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

This is the first episode of a three-part series with Elizma Lambert, where we delve into the world of the Organic Acids Test (OAT) and its crucial role in optimizing health. In this episode, we get started on our analysis of Organic Acids Test (OAT) and its essential role in naturopathic medicine and precision health.  Elizma Lambert, a seasoned expert with over 20 years of experience, discusses the legitimacy and applications of functional health tests, especially the OAT test.  First, we specifically look at fungal infections like Candida, and look at how these tests diagnose complex conditions by examining the intricate relationships with symptoms and signals.  We'll explore the benefits of a holistic approach to health, moving beyond quick fixes to address genetic predispositions through multi-dimensional health strategies. 

In this episode, we dive deep into the world of precision health with Dr. Michael Snyder, a renowned professor of genetics at Stanford University and the chair of the genetics department.  Join us as Dr. Snyder shares his groundbreaking insights on the latest advancements in precision medicine, biohacking, and personalized healthcare.  Discover how cutting-edge technology, supplements, and genetic research can optimize your longevity and overall wellness.  Tune in to learn how you can leverage precision medicine to enhance your longevity and improve your health. Don't miss out on the transformative potential of these innovations to help you live a longer, healthier life. If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/

In this episode, Joe speaks with Jean Fallacara, a multifaceted entrepreneur, neuroscientist, and calisthenics enthusiast.  Jean shares insights on how he maintains peak performance through biohacking, focusing on supplements, exercise routines, and meditation practices.  Joe and Jean dive deep into the realms of precision health, genetic testing, and maintaining a balanced, enjoyable lifestyle while pursuing optimal health.  Tune in for an engaging discussion on fitness tips, the importance of diet, and how to transform your health regimen! If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ Timestamps: (0:00) - Introduction (19:44) - Jean's top supplements (30:55) - Jean's diet (35:41) - Mindset hacks

In this episode, Joe dives into the complex world of proline supplementation. He discusses the impacts proline has on collagen synthesis, aiming for improved skin health, enhanced wound healing, and better exercise recovery.  However, the journey took an unexpected turn as Joe explains the biomechanics behind why he experienced several side effects such as anxiety, restlessness, and hypochondriac behaviors. Throughout the episode, Joe explores: The intended benefits of proline for collagen synthesis and recovery The biochemical interaction of proline with lysine and vitamin C as per the Linus Pauling protocol The severe side effects experienced due to high doses of proline and the genetic predisposition affecting glutamate metabolism Strategies attempted to mitigate these effects Join Joe as he unpacks the lessons learned from his proline supplementation experiment, shedding light on the potential risks and the importance of understanding one's genetic makeup before undertaking such regimens. If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

Join Joe as he takes a closer look at saffron, a spice revered not just for its flavor but for its impressive health benefits.  In this deep dive, Joe explores how saffron could potentially outshine caffeine in enhancing mental clarity and focus.  This episode goes in-depth on how saffron impacts various aspects of health, from improving sleep quality to reducing gut inflammation and boosting immune function. Discover the comprehensive effects of saffron on: Mental Focus: How saffron compares to caffeine in enhancing cognitive performance. Sleep Quality: The role of saffron in promoting restful sleep and adjusting sleep cycles. Gut Health & Immunity: Insights into saffron's anti-inflammatory properties and its implications for gut health and immune system support. Exercise Recovery: Exploring the potential benefits of saffron in reducing muscle soreness and speeding up recovery times. If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

Join Joe as he delves into his journey with MSM (Methyl Sulfonyl Methane) supplementation, a key to detoxing the body and enhancing recovery.  In this episode, Joe discusses: The Impact of Heavy Metals on Health: Understanding the dangers of heavy metals and the importance of detoxing them from our bodies. MSM as a Detox & Methylation Aid: How MSM supplementation helps clear heavy metals and play a vital role in methylation. Recovery and Resilience Through MSM: How MSM aids in the recovery of tendon and joint injuries, contributing to better exercise outcomes. Combining Sulfur Sources for Optimal Detox: Strategies in integrating MSM with other sulfur sources. Enhanced Health Markers: Insights into how MSM positively influences key health markers like homocysteine, DHEA sulfate, ALT, and HSCRP. Discover the powerful role of MSM in detoxing heavy metals and enhancing physical recovery.  Tune in to learn how this supplement could revolutionize your approach to health and detoxification. If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

Buy Jo's Resistant Starch on Amazon Join Joe as he explores the powerful benefits of resistant starch as a natural alternative to Ozempic.  In this episode, Joe dives into how resistant starch not only supports weight management and cognitive function but also promotes gut health—all without the side effects associated with pharmaceutical options like Ozempic. Joe discusses: Resistant Starch for Health: How this natural supplement enhances the production of butyrate, GLP-1, and how these play significant roles in weight loss, muscle growth, and overall health improvement. Cognitive and Mood Enhancement: Insights into how increasing BDNF levels through butyrate production can boost cognitive functions and mood. Comparison with Ozempic: Joe compares the effects and side effects of resistant starch with Ozempic, providing a detailed analysis based on his personal experiences and scientific research. Practical Advice on Dosage: Detailing the specific dosage of resistant starch used in a recent study published in Nature in 2024, which demonstrated substantial benefits in weight management. Tune in to learn why resistant starch might be the key to achieving your health goals naturally, making it a foundational supplement for enhancing immune function, preventing chronic diseases, and improving cognitive health. If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

In this episode, Joe has an in-depth conversation with Dr. Rita Marie, a licensed doctor of chiropractic and the founder of the Institute of Nutritional Endocrinology, about the importance of personalized healthcare in addressing insulin, thyroid, adrenal, and digestive imbalances through the integration of genetics and lifestyle changes.  Dr. Rita Marie discusses her approach to helping patients by not only looking at conventional lab tests but also incorporating genetics and lifestyle factors such as diet, sleep, and stress management to create a comprehensive health strategy.  She emphasizes the necessity of moving beyond one-size-fits-all solutions to tackle health challenges, the motivational power of understanding one's genetic predispositions, and the significance of practitioners being curious and knowledgeable about nutritional biochemistry and genetics.  Additionally, the conversation delves into the necessity of optimizing health before issues become irreversible and highlights some of the common markers and supplements considered in Dr. Rita Marie's practice. - If you're a health practitioner, visit inemethod.com - Visit https://drritamarie.com/ If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

In this episode, Joe dives deep into the effects of megadosing AKG (Alpha Ketoglutarate), a crucial supplement in metabolic pathways and its implications for longevity. Discover the risks and rewards as Joe recounts increasing his AKG intake to 15 times the standard dosage, leading to notable side effects such as enhanced anxiety and sleep issues.  Joe meticulously explains the biochemical transformation of AKG into glutamate and reviews strategies to counteract these negative impacts, including the use of supplements like B6 and Niacin.  He concludes by weighing the pros and cons of AKG. Tune in to learn more about AKG supplementation, its potential benefits, and how to safely navigate its use for optimal health outcomes If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

In this episode, we delve into the pivotal role of the BHMT gene within the body's methylation process.  We discuss how the BHMT enzyme is essential for catalyzing a vital reaction that transforms homocysteine into methionine.  Additionally, we cover the importance of betaine in enhancing the methylation cycle. Betaine acts as a methyl donor, particularly in the reaction facilitated by the BHMT enzyme, making it crucial for reducing homocysteine levels and supporting cardiovascular and neurological health. We also explore the complexity of methylation pathways and emphasize the need for a comprehensive evaluation of multiple genes to truly understand and optimize methylation. Be sure to follow our podcast for more expert insights into how betaine, methylation, and genetics can be leveraged to optimize both body and brain health. If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

In this episode, Joe tackles a controversial new study that suggests even 25 milligrams of niacin could potentially increase the risk of heart disease.  Delving deep into the world of niacin supplementation, Joe discusses how, despite these concerns, niacin offers numerous health benefits, including enhanced cognitive function, better mood, and increased energy levels. Joe draws on personal experiences to compare the negatives against the significant positives of niacin, as he explores niacin's biochemical effects, particularly its interaction with proteins such as 2PY, 4PY, and VCAM1, all linked to cardiovascular health.  Throughout the episode, Joe examines the importance of dosage, sharing insights into the varying effects of low versus high doses of niacin.  Join Joe as he navigates the complexities of niacin use, advocating for a well-informed, nuanced approach to its benefits and risks. If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

In this episode, we explore the complex interplay between the CNR1 gene, cannabinoid receptors, and cannabis.  Discover the role of the endocannabinoid system in maintaining bodily balance, particularly in brain function, mood regulation, and inflammation response.  We delve deep into how genetic variations in the CNR1 gene can influence the CB1 receptors, and the implications of CB1 receptor function in managing stress, anxiety, and cognitive processes such as memory and decision-making.  Whether you're curious about the science behind getting high or looking for ways to optimize your cannabinoid system through diet and supplements like CBD oil, this episode has something for everyone.  If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

In this episode, we explore the crucial role of serotonin in managing anxiety and enhancing mental wellbeing.  Discover how serotonin not only influences mood but also plays a pivotal role in anxiety regulation and mental health.  Learn about the HTR1A and HTR2A genes, which act like switches, controlling the serotonin levels in the brain.  Understanding the SNPs in these genes can provide personal insights into your serotonin activity, offering potential strategies to alleviate anxiety, depression, and other mental health disorders.  The episode further discusses how various serotonin receptors, affected by genetic differences, impact numerous physiological and psychological functions.  Gain practical advice on how to balance your serotonin levels through diet, lifestyle choices, and supplements tailored to your genetic makeup, and see how this can significantly improve your mood and reduce anxiety.  If you're interested in learning more about how your DNA and genetics affect your health: - Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/

In this episode, Joe takes questions from SelfDecode members, answering questions like: What makes SelfDecode different from other DNA companies? How does the recommendations engine work? Can you find out if a certain supplement is right for you? Plus, he shares some of his genetic predispositions and how they correlate with his lab levels! - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/ 

In this episode, we delve into the critical process of methylation, highlighting its significant impact on health issues ranging from heart disease to mental health and focusing on a lesser known methylation gene - MTHFD1. We focus on the MTHFD1 gene and choline's significance beyond methylfolate and Vitamin B12 for undermethylators.  Discover how MTHFD1 impacts methylation by metabolizing tetrahydrofolate and how choline is important in supplying methyl groups.  We highlight the impact of a negative MTHFD1 variant on choline usage and the potential consequences of choline deficiency, while also stressing the importance of considering other genes involved in methylation, not just MTHFR and MTHFD1. If you're interested in learning more about how your DNA and genetics affect your health, you can: - Check out SelfDecode: https://selfdecode.com/ - Join Joe's online community: https://thejoecohenshow.com/