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What if your diagnosis wasn't the beginning of the end — but the beginning of everything? Eight years ago, Bettina Gordon-Wayne was handed a breast cancer diagnosis on a beautiful spring day in Washington, D.C. She had a four-year-old at home, a healthy lifestyle, and zero warning signs. Today, she is eight years cancer-free and biologically 12 years younger than her chronological age. And she has the data to prove it. Bettina spent 30 years as an international journalist interviewing world leaders, billionaires, and global experts. She was always the one asking the questions — until life gave her a story she couldn't cover from a distance. So she turned her investigative rigor toward the science of longevity, logged thousands of hours of research, and rebuilt her health from the inside out. Her TEDx talk "Aging Well, Aging in Reverse" surpassed 100,000 views. Her book The Joy of Later Motherhood sparked a global conversation. And her program, Younger With Age, is helping high-achieving midlife women do exactly what she did — reverse their biological age with data that proves it. In this episode, Dr. Anna and Bettina cover: Why biological age matters far more than the candles on your birthday cake How Bettina conceived naturally at 43 after a year of failed attempts — and what changed The mindset shift that separates women who age slowly from women who don't Why healthy living didn't prevent cancer — and how it saved her life anyway The unsexy, free anti-aging strategy that outperforms every biohack How to become a "beauty hunter" and lower cortisol through intentional joy The two words to say to anyone who tells you your best years are behind you Memorable Quotes: We can have true agency over the way we age. — Bettina Gordon-Wayne We can truly get younger with age.— Bettina Gordon-Wayne Get out of the victimhood and become defiant.— Bettina Gordon-Wayne The goal is not just to get older. The goal is to create a life that you are excited to live. — Bettina Gordon-Wayne If anybody tells you that you're too old, too gray, that your ship has sailed, look them straight in the eye and tell them two words: Watch me.— Bettina Gordon-Wayne "Our body is the cathedral of our spirit." — Dr. Anna Cabeca "For every day God gives us, let it be as healthy, vital, and purposeful as possible." — Dr. Anna Cabeca "Health shows vitality." — Dr. Anna Cabeca "Your diagnosis is not your destiny." — Dr. Anna Cabeca "Your diagnosis is not your destiny." — Dr. Anna Cabeca "Our body is the best pharmacy in the world." — Dr. Anna Cabeca Take Bettina's free biological age quiz at bettinagordon.com/quiz and learn more about the Younger With Age program at bettinagordon.com/program. Key Timestamps: 00:00 — Dr. Anna opens: "Our body is the cathedral of our spirit" — why renovation and repair are the foundation of longevity 02:15 — Introducing Bettina: from international journalist to first-time mom at 44 to breast cancer survivor to 12 years biologically younger 04:00 — Can we actually reverse biological age in our 50s and 60s? Bettina's answer is a clear yes 06:30 — Bettina's journey to later motherhood: why she didn't want children, what shifted at 43, and conceiving naturally after a year of failed attempts at 40 12:00 — Chronological age vs. biological age: what the difference actually means, the Horvath clock, and why biological age is the only number that matters 16:45 — "I don't do cancer, I do health" — the moment Bettina's world stopped on a spring day in D.C. 20:00 — Why a healthy lifestyle didn't prevent the diagnosis — and why her oncologist said it saved her life anyway 24:30 — The epigenetics of breast cancer: how choices made in your 30s show up as disease in your 40s and 50s 27:00 — "Get out of the victimhood and become defiant" — the mindset non-negotiable for aging on your own terms 31:00 — The racehorse framework: is this racehorse food or mule food? A reframe that makes healthy choices feel like self-respect, not deprivation 36:00 — The unsexy truth: sleep, movement with joy, stress reduction, and community are the top anti-aging strategies — and they're free 40:00 — "Become a beauty hunter" — Bettina's favorite daily practice for regulating the nervous system and activating the parasympathetic state 44:00 — Lab markers worth tracking: hemoglobin A1C, hsCRP, fatty acid ratios, vitamin D, and the biological age testing companies worth knowing 49:00 — Loving a body full of scars: what Bettina sees in the mirror at 56 and why it has nothing to do with how it looks 53:00 — "Watch me" — Bettina's closing message to every woman who has been told she's too old, too gray, or that her ship has sailed Connect with Bettina: LinkedIn: linkedin.com/in/bettinagordon TikTok: @bettina.gordon TEDx Talk: Aging Well, Aging in Reverse Connect with Dr. Anna: Website: Dranna.com Instagram: @thegirlfrienddoctor YouTube: @thegirlfrienddoctor TikTok: @drannacabeca Facebook: thegirlfrienddoctor
"Insurance is there for when you're sick or when something goes incredibly wrong. It's not there for prevention."The traditional healthcare system is designed to treat you when you are sick. You go to a doctor for 15 minutes, get a basic blood panel, and if you are within the "reference range," you are told you are fine. The goal of this system is to get you from -1 back to 0.My guest this week is Prabhat Dhar, the Head of Growth for Superpower, a new platform that wants to take you from 0 to 100. Rather than treating late-stage diagnoses, Superpower provides comprehensive biomarker testing, looking at advanced metrics like ApoB, Fasting Insulin, and HSCRP, to detect diseases like cardiovascular risk or metabolic dysfunction up to a decade before they materialize as claims.In this episode, we discuss how Superpower translates complex biological data into a highly personalized, AI-driven action plan for your health (and your lifestyle). We also dive into why employers must stop relying on health insurance carriers to manage wellness, the power of decoupling proactive screening from the traditional system, and how to start bending the cost curve by focusing on root-cause analysis instead of late-stage symptom management.If you want to know what the future of employee health benefits looks like when it's built on individual biology instead of group claims data, this episode is for you.Thank you to our 2026 sponsors!ParetoHealth: ParetoHealth empowers midsize employers with a long-term solution to reduce volatility and lower overall health benefits costs. Visit https://www.paretohealth.com/fully-insured-vs-self-funding-with-paretohealth-spencer-podcast/?utm_source=youtube&utm_medium=referral&utm_campaign=SelfFundedwSpencer to learn more.Samaritan Fund: A program that connects those who need help to the support they need. We are proud to offer the Samaritan Fund Program. Visit SamaritanFundProgram.com to learn more.Vālenz Health: We're Vālenz Health, your partner in improving health literacy, reducing plan spend, and delivering high-value healthcare. Visit ValenzHealth.com to learn more.Imagine360: Imagine360 helps self-funded employers save on healthcare with smarter health plans. Cut expenses by 20-30% with custom solutions. Contact us today at Imagine360.com.Episode Chapters(00:00:00) Intro: Getting from 0 to 100 (Not Just -1 to 0) (00:01:21) Why the Primary Care "Quarterback" System is Broken (00:04:47) Decoupling Proactive Health from Health Insurance(00:07:42) The Origin Story of Superpower & Treating Crohn's Disease (00:12:06) Democratizing "Concierge" Functional Medicine (00:15:22) Why Traditional Blood Tests Miss the Real Signals (00:19:06) Translating Biomarkers into Personalized Action Plans (00:23:44) Overcoming "Point Solution Fatigue" with Biological Data (00:27:55) The Superpower Member Experience: How It Works (00:31:41) Integrating an AI Doctor Chat and Clinical Teams (00:33:42) How Superpower Augments Direct Primary Care (DPC) (00:41:22) The 5 Biomarkers You Need to Be Testing For (00:49:36) Moonshot: The Future of the "Health Super App" (00:54:51) Closing Thoughts: Moving from Success to SignificanceKey Links for Social:@SelfFunded on YouTube for video versions of the podcast and much more - https://www.youtube.com/@SelfFundedListen/watch on Spotify - https://open.spotify.com/show/1TjmrMrkIj0qSmlwAIevKA?si=068a389925474f02Listen on Apple Podcasts - https://podcasts.apple.com/us/podcast/self-funded-with-spencer/id1566182286Follow Spencer on LinkedIn - https://www.linkedin.com/in/spencer-smith-self-funded/Follow Spencer on Instagram - https://www.instagram.com/selffundedwithspencer/
"Insurance is there for when you're sick or when something goes incredibly wrong. It's not there for prevention."The traditional healthcare system is designed to treat you when you are sick. You go to a doctor for 15 minutes, get a basic blood panel, and if you are within the "reference range," you are told you are fine. The goal of this system is to get you from -1 back to 0.My guest this week is Prabhat Dhar, the Head of Growth for Superpower, a new platform that wants to take you from 0 to 100. Rather than treating late-stage diagnoses, Superpower provides comprehensive biomarker testing, looking at advanced metrics like ApoB, Fasting Insulin, and HSCRP, to detect diseases like cardiovascular risk or metabolic dysfunction up to a decade before they materialize as claims.In this episode, we discuss how Superpower translates complex biological data into a highly personalized, AI-driven action plan for your health (and your lifestyle). We also dive into why employers must stop relying on health insurance carriers to manage wellness, the power of decoupling proactive screening from the traditional system, and how to start bending the cost curve by focusing on root-cause analysis instead of late-stage symptom management.If you want to know what the future of employee health benefits looks like when it's built on individual biology instead of group claims data, this episode is for you.Thank you to our 2026 sponsors!ParetoHealth: ParetoHealth empowers midsize employers with a long-term solution to reduce volatility and lower overall health benefits costs. Visit https://www.paretohealth.com/fully-insured-vs-self-funding-with-paretohealth-spencer-podcast/?utm_source=youtube&utm_medium=referral&utm_campaign=SelfFundedwSpencer to learn more.Samaritan Fund: A program that connects those who need help to the support they need. We are proud to offer the Samaritan Fund Program. Visit SamaritanFundProgram.com to learn more.Vālenz Health: We're Vālenz Health, your partner in improving health literacy, reducing plan spend, and delivering high-value healthcare. Visit ValenzHealth.com to learn more.Imagine360: Imagine360 helps self-funded employers save on healthcare with smarter health plans. Cut expenses by 20-30% with custom solutions. Contact us today at Imagine360.com.Episode Chapters(00:00:00) Intro: Getting from 0 to 100 (Not Just -1 to 0) (00:01:21) Why the Primary Care "Quarterback" System is Broken (00:04:47) Decoupling Proactive Health from Health Insurance(00:07:42) The Origin Story of Superpower & Treating Crohn's Disease (00:12:06) Democratizing "Concierge" Functional Medicine (00:15:22) Why Traditional Blood Tests Miss the Real Signals (00:19:06) Translating Biomarkers into Personalized Action Plans (00:23:44) Overcoming "Point Solution Fatigue" with Biological Data (00:27:55) The Superpower Member Experience: How It Works (00:31:41) Integrating an AI Doctor Chat and Clinical Teams (00:33:42) How Superpower Augments Direct Primary Care (DPC) (00:41:22) The 5 Biomarkers You Need to Be Testing For (00:49:36) Moonshot: The Future of the "Health Super App" (00:54:51) Closing Thoughts: Moving from Success to SignificanceKey Links for Social:@SelfFunded on YouTube for video versions of the podcast and much more - https://www.youtube.com/@SelfFundedListen/watch on Spotify - https://open.spotify.com/show/1TjmrMrkIj0qSmlwAIevKA?si=068a389925474f02Listen on Apple Podcasts - https://podcasts.apple.com/us/podcast/self-funded-with-spencer/id1566182286Follow Spencer on LinkedIn - https://www.linkedin.com/in/spencer-smith-self-funded/Follow Spencer on Instagram - https://www.instagram.com/selffundedwithspencer/
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Text Dr. Lenz any feedback or questions Three Blood Tests That Reveal Your True Heart Attack Risk: hsCRP, Lipoprotein(a), and ApoBDr. Michael Lenz argues the standard lipid panel can miss key drivers of atherosclerosis, explaining why some people with “normal” LDL still have heart attacks, and recommends three additional blood tests to better assess risk. High-sensitivity C-reactive protein (hsCRP) measures inflammation, with higher levels indicating increased risk and supported by the JUPITER trial showing benefit of statins in people with normal LDL but elevated hsCRP. Lipoprotein(a) is a largely genetic, “extra dangerous” LDL-related particle linked causally to heart attacks, strokes, and aortic valve disease; a one-time adult test is recommended, especially with early family history, and high levels warrant aggressive control of other risk factors while targeted therapies are in trials. ApoB counts atherogenic particles and may predict risk better than LDL, particularly with insulin resistance or diabetes.00:00 Hidden Heart Attack Risk01:53 Inflammation Fire Alarm03:06 hsCRP Risk Levels04:21 Lipoprotein A Genetics06:08 What to Do If High06:59 ApoB Particle Count08:27 ApoB Targets and Discordance09:23 Putting the Three Together10:17 Final Takeaways and Next Steps Support the showWhen I started this podcast and YouTube Channel—and the book that came before it—I had my patients in mind. Office visits are short, but understanding complex, often misunderstood conditions like fibromyalgia takes time. That's why I created this space: to offer education, validation, and hope. If you've been told fibromyalgia “isn't real” or that it's “all in your head,” know this—I see you. I believe you. This podcast aims to affirm your experience and explain the science behind it. Whether you live with fibromyalgia, care for someone who does, or are a healthcare professional looking to better support patients, you'll find trusted, evidence-based insights here, drawn from my 29+ years as an MD.Please remember to talk with your doctor about your symptoms and care. This content doesn't replace per...
Walking into a cardiologist appointment is more often than not walking into a time machine. Not only the discussions about disproven risks but unfortunately the outdated tools and technology that have little to no predictive or preventative potential. The worst part is the technology exists that can identify to the microscopic level the type of plague actually causal to more than 80% of heart-attacks! That's what Dr Osborne and ClearCardio are doing right now.Dr. John Osborne is a cardiologist and the founding director of State of the Heart Cardiology, with a strong focus on preventive and non-invasive cardiovascular care. He holds an M.D. magna cum laude, a Ph.D. in cardiovascular physiology, and completed postdoctoral training at Harvard Medical School and Brigham and Women's Hospital. Uniquely board-certified across multiple disciplines, his work spans metabolic health, cardiovascular genetics, and advanced cardiac imaging. Dr. Osborne has received the American Heart Association's Cardiac Care Provider of the Year award. He is also the founder of ClearCardio™, where he is advancing proactive heart health through the use of AI-driven diagnostics and personalized care.Contact:Youtube - https://www.youtube.com/@ClearCardioWebsite - https://clearcardio.comJoin us as we explore:Why EKGs and CAC scores offer far less than advertised.Why so much that happens in a cardiologists office are 20th century tools, and why ClearCardio's cutting-edge AI biotech offers lifesaving preventative potential.AI's ability to identify and quantify plague to the 10th of a cubic millimeter!CT vs MR, the different types of arterial plague (hard, soft, lipid rich, active) , why 86% of heart attacks will never show up on your CAC scoreWhy strokes and heart disease are far more connected than appreciated, and how the cholesterol story has misguided us.Why blood markers like hsCRP are far more critical to understanding cardiovascular disease than even I appreciated.MentionsProduct - OMRON, https://omronhealthcare.com/products/evolv-wireless-upper-arm-blood-pressure-monitor-bp7000Test - Cleerly, https://cleerlyhealth.comSupport the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/
Estrogen and cholesterol are more connected than most doctors discuss. Dr. Alison DiBarto Goggin breaks down exactly what estradiol does for your cardiovascular system, why midlife women see lipid shifts that have nothing to do with diet, and what functional testing and targeted support actually look like. Covers ApoB, Lp(a), MPO, hsCRP, Lp-PLA2, insulin, homocysteine, thyroid, and the production vs. clearance framework. Practical supplementation including methylfolate, folinic acid, berberine, omega-3s, bergamot, and CoQ10. This is the conversation you didn't get at your annual physical. Find Dr. Alison at littleblackbagmedicine.com Quest Labs with Discount: https://us.fullscript.com/j/alison-goggin Fullscript Supplements: https://us.fullscript.com/plans/littleblackbagmedicine-estrogen-cholesterol
Your TSH is "normal." Your ferritin is "normal." Your glucose is "normal." And IVF still isn't working. Here's why normal lab ranges were never built for fertility and what optimal actually looks like. Most reference ranges are designed to flag disease in the general population, not to optimize egg quality, embryo competence, or implantation. That gap is where a lot of unexplained IVF failure, embryo arrest, and recurrent loss live. In this episode, Sarah Clark walks through the four biomarker categories most often dismissed as "fine" but influence cycle outcomes in women with diminished ovarian reserve, low AMH, high FSH, and failed transfers. What you'll learn: - What "normal" lab ranges actually measure and what they miss - Why fertility-optimized TSH sits closer to 1–2 mIU/L, not 4.0 - Ferritin 80–100 ng/mL and what it means for egg energy and endometrial development - Fasting glucose under 86, insulin stability, and follicular development - Why hsCRP under 1 mg/L matters for implantation and embryo quality - The full thyroid panel most REIs skip: Free T3, Free T4, Reverse T3, TPO, TBG - Male factor inflammation, sperm DNA fragmentation, and recurring infections - The reframe: normal protects against disease, optimal supports conception Timestamps: 00:00 Why "normal" labs don't mean fertility-optimized 00:30 What conventional reference ranges actually measure 01:30 Why DIY fertility optimization stalls without functional lab review 03:00 TSH "normal" vs optimal and the full thyroid panel REIs skip (Free T3, Free T4, Reverse T3, TPO, TBG) 04:30 How thyroid signaling affects egg quality, ovulation, and pregnancy loss 05:00 Ferritin 80–100 ng/mL: the iron range for IVF and egg energy 06:00 Fasting glucose under 86, insulin stability, and follicular development 07:00 hsCRP under 1 mg/L: low-grade inflammation, implantation, and embryo development 07:30 Male factor inflammation, sperm DNA fragmentation, and recurring infections 08:30 Embryo Audit Checklist + Functional Fertility Second Opinion: next steps This conversation is for women navigating diminished ovarian reserve, low AMH, high FSH, embryo arrest, implantation failure, or recurrent pregnancy loss who keep being told their bloodwork looks fine. Not sure what's been fully evaluated? Download the free Embryo Audit Checklist to map your past cycles and labs so you can see what's been looked at and what may have been missed.
In this episode, Cheryl interviews Dr. Christo Frangopoulos about how certain lifestyle factors related to cancer. Most people overlook one of the most powerful tools in preventing cancer: movement. Dr. Christo Frangopoulos reveals surprising facts about how simple lifestyle shifts, like breaking up sedentary time, can drastically cut your risk of cancer and boost your body’s ability to fight it. If you’re tired of just hearing “eat healthy and exercise,” this episode uncovers actionable strategies backed by the latest science to enhance your health span. Discover why sitting is just as dangerous as smoking when it comes to cancer risk, and learn the practical tips to make movement a seamless part of your day. From how often to get up during work hours to the science of muscle-derived anti-cancer proteins called myokines, Dr. Christo shares insights that can change your approach to health. We break down the true impact of sedentary behavior, the science behind autophagy and muscle contraction, and the critical role sleep plays in cellular repair and cancer prevention.You’ll also uncover: the truth about alcohol's relationship with cancer, the importance of inflammation markers like CRP, and why maintaining consistent sleep and circadian rhythms is crucial for lowering risk. This episode is perfect for anyone looking to take control, whether you’re battling family history or just want to live longer healthier lives.Dr. Christo Frangopoulos is an anesthesiologist, lifestyle medicine expert, and personal trainer known for integrating science-backed strategies to improve health outcomes across the U.S. His insights on cancer prevention through lifestyle modifications are revolutionary yet accessible, making this a must-listen for health-conscious individuals and medical professionals alike. Don’t miss this opportunity to turn simple daily habits into potent cancer-fighting tools. Your health journey starts with the right knowledge and this episode delivers it. Hit play now and learn how to reframe your lifestyle for longevity and resilience. Visit Dr. Frangopoulos at AltasMD360.com Takeaways How sedentary behavior independently increases cancer risk, even with regular exercise The importance of muscle contraction and myokines in fighting cancer Lifestyle changes that can lower the risk of developing common cancers, especially colorectal cancer in young adults The critical role of sleep in DNA repair and cancer prevention The impact of inflammation markers like CRP on cancer risk Rethinking alcohol consumption and its nuanced effects on health Practical habit formation techniques, including the ‘two days’ rule for sustainability Resources for health professionals and individuals via AtlasMD360.com Book: The Telomere Effect by Elizabeth Blackburn & Elissa Epel A scientific approach to aging and health Disclaimer: Links may contain affiliate links, which means we may get paid a commission at no additional cost to you if you purchase through this page. Read our full disclosure here. Watch on YouTube: Disclaimer: Links may contain affiliate links, which means we may get paid a commission at no additional cost to you if you purchase through this page. Read our full disclosure here. CONNECT WITH CHERYL Shop all my healthy lifestyle favorites, lots of discounts! 21 Day Fat Loss Kickstart: Make Keto Easy, Take Diet Breaks and Still Lose Weight Avaline Wines, Tested and Clean, Sugar Free Drinking Ketones Wild Pastures, Clean Meat to Your Doorstep 20% off for life Clean Beauty 20% off first order DIY Lashes 10% off NIRA at Home Laser for Wrinkles 10% off or current promo with code HealNourishGrow Instagram for daily stories with recipes, what I eat in a day and what’s going on in life Facebook YouTube Pinterest TikTok Amazon Store The Shoe Fairy Competition Gear Getting Started with Keto Resources The Complete Beginners Guide to Keto Getting Started with Keto Podcast Episode Getting Started with Keto Resource Guide Episode transcript: Cheryl McColgan (00:00)Hey everyone, I’m Cheryl McColgan, founder of HealNurshGrow and today I’m really excited to be joined by Dr. Christo Frangopoulos and he is kindly letting me shorten his name to Dr. Chris or Chris, but he will introduce himself here in a moment. And why I really wanted to have Dr. Frangopoulos on today is because he is a board certified anesthesiologist. He’s also a lifestyle medicine doctor and he’s a personal trainer. So, you know, those are all things if you’re a listener to this podcast that I am super excited about and that I love to chat about. take it from here and just introduce yourself and share with people what you’re all about and what you’re here to talk about today. Christo (00:35)Wonderful. Well, I just wanna say thank you so much for having me. This is an honor and I really hope we can reach at least a few people out there to make a difference with the information I’m going to be sharing with Cheryl. As Cheryl said, my name is Christof Rangaples. It’s much easier just to say Chris. I am an anesthesiologist for about a decade now. I have also got board certified in lifestyle medicine and a certified personal trainer and a lot of what I do is share information that’s evidence-based and science-backed that can optimize people’s lifestyle. As a physician, I travel the country, I’m certified in about 10 different states, and the problem of healthcare is it’s everywhere. And the state of our nation can really utilize a change in how we attack our health. And I think lifestyle medicine offers so many great tools and it’s super helpful. It’s not overly complicated and can make a huge difference. Cheryl McColgan (01:39)It’s so nice to have a doctor on that really appreciates that because I think so often, you we have more of a sick care system than health care system. And I’m sure that we’ll get into that a little bit more. But the fact that you are trained in lifestyle medicine, that you recognize the significance and the importance of it, I think is a huge step in the right direction for the medical field. So I’m so glad that you’re kind of promoting that and you have all that information on your website, all your good programs and continuing education. So I think that will be a huge benefit to the medical community. But one of the things that you’re Christo (01:49)Yes. Yeah. Yeah. Cheryl McColgan (02:09)particularly interested when your team reached out is around cancer. And some people that know me personally or know some of my work and some of my writing will know that I have a lot of cancer in my family. And it’s a big reason that I do a lot of the things that I do in my health and my life. So what what have you how did you become interested in cancer specifically? And then let’s start with like what your number one top lifestyle change people can do to prevent cancer. Christo (02:39)Sure. So as an anesthesiologist, you can imagine we see every sort of surgery from something simple to very complicated cancer cases. And over my years, I’ve seen a lot of cancer surgeries and how they’ve affected. their families, their communities, and it really is a, it’s something that every one of us have experience with, whether it’s yourself or a family member or a friend or a coworker, we are all affected by cancer and it is everywhere. But the truth of the matter is a lot of lifestyle change can actually make a huge difference in our cancer rates across the country. And most people probably don’t know this, but only about five to 10 % of cancers are from inherited gene mutations. Okay, so the other 90 % are often attributed to either a lifestyle or environmental exposures. So, you know, a lot of people think they’re destined to get cancer because their family member has a cancer or whatnot. That is a small chunk of cancer. It is actually our lifestyle and environmental exposures that can affect getting cancer, how we respond to cancer, and the aftermath of that, either being successful in treatment or not. And there’s a lot of things we can do for it. Cheryl McColgan (04:12)Yeah, just to drive that point home, share that we were talking before we started recording and Dr. Christo was just kindly asking me if there was any, you know, thing to avoid around cancer because I had said that it’s a lot in my family and it’s been a while and it’s always going to be hard. But my dad, when I was around, he was one of the first runners in the running boom, always going to the health food store, did all these super healthy lifestyle behaviors before this was really popular. And so was quite shocking, you know, when he ended up having these multiple cancer diagnosis later in But as a young man, he, we lived in the south, we live in Louisiana, and this is in the 70s before a lot of OSHA things and whatever, and he worked in chemical plants. And he was a chemist by trade. you know, so I’m pretty fully convinced that for him, it was those environmental factors that you spoke of. So in addition to being in an environment like that, that’s kind of an obvious situation. What are maybe some things that aren’t as obvious that people might be exposed to that they can limit in order to prevent cancer? Christo (05:10)Yeah, and not to scare anyone right now, but it’s kind of what we’re doing. We’re being sedentary, we’re sitting down right now. it is, sedentary behavior is ubiquitous in our culture, right? It’s how we do work every day. A lot of people sit at their desks in the office and there’s sometimes little movement. Well, we know a lot of things, what are causes of cancer and actually sedentary behavior. Even if you meet all of the activity guidelines, sedentary behavior itself is an independent risk factor for getting cancer. Of course, there’s a bunch of numbers with these, but it’s something that a lot of people don’t even think about. And an easy solution is trying to get up and get moving every so often. For myself, am I stuck at an office or in an operating room case, in their long cases, I make sure I’m getting up. every single hour on the hour, something I can remember just to get moving. And we’ll talk more in depth about this, but movement itself is as a prevention for not only cancer, but a number of other things. But yes, sedentary behavior is a big one that we really don’t think about very much. And a lot of us are exposed to that. Cheryl McColgan (06:27)Yeah, and I just want to I kind of want to build on something that you said just to make it super clear for people because I know this information, but if this is the first time somebody’s hearing it, they might not understand it. So I think the recommendation right now is correct me if I’m wrong, because I know you’ll know the right answer to this. It’s like 150 minutes per week of physical activity for most adults. Right. But you’re I think what you’re saying is, OK, say you do that. You go to the gym and you do your 150 minutes. That’s not the end. It’s actually been that eight hours that you’re sitting at your desk is still putting that on top Christo (06:45)Mm-hmm. Yeah. Yep. Yes. Yes, so you are correct. It is 100, so the physical activity guidelines is 150 to 300 minutes of moderate intensity activity per week. It could also be 75 to 150 minutes of vigorous intensity activity or a combination of both knowing that one minute of vigorous intensity activity is equal to two minutes of moderate intensity activity. All that being aside. 150 minutes of moderate activity per week is the goal. It’s something easy to remember. But yes, this sedentary behavior is independent of that. So if you’re going to the gym and you’re hitting all your marks, it doesn’t give you license so much to go home and be a cash potato the rest of the day. And that’s kind of the idea here. When we look at all of these different factors, it really comes down to getting your blood flowing. No, it’s more than that, that’s simplistic explanation. But the simple answer is get your butt up, get moving, get your blood flowing, and it’s something that we have to make it habitual. And again, we have such a sedentary lifestyle, it doesn’t mean we’re not doing anything, it just means that we’re sitting at a chair at the office, we’re at the desk all day, we’re typing on the computer. It’s just how our lives are built. So we therefore have to change the environment around us to make sure that we aren’t so sedentary. And there’s a number of things that we can do for that. Cheryl McColgan (08:30)So what would be some of your favorite tips for people? mean, I think you mentioned saying getting up on the hour, everybody has a cell phone nowadays, so setting alarms or using apps. What are some other things besides that that people might do to kind of combat this sedentary behavior? Christo (08:36)Yeah. Yeah. Sure, so that’s a big one for me. It’s something very easy to remember. On the hour, every hour, get up and get moving. Now if you’re at the office or if you’re somewhere where you’re not at home, make sure you are going to the restroom that’s farthest away from you, using the kitchen or water fountain that’s not close to you, walking up and down the stairs just to get moving. It doesn’t have to be difficult. It doesn’t have to be You know, I have to meet these marks. The simple answer is just get up, get moving, incorporate it into your day that’s seamless. That’s something that easy to remember for you. Maybe it’s you have a favorite coffee station at the office, whatever may be, just try to make it make sure that you’re able to incorporate as much movement as you can. Cheryl McColgan (09:37)I think that’s really clear. So we want people to go to the gym. We want them to be strength training so they can prevent sarcopenia, maintain their muscle mass. That’s all great for metabolic health, but we also just need people to just get out of the chair from their desk or away from the TV and just move Christo (09:44)Mm-hmm. Yeah. one of the most simple things that we can be doing to prevent cancer. And of course, there is more to exercise in cancer prevention. We’re talking about sedentary behavior, but it also can go from light to moderate activity, vagus activity, and then meeting the guidelines. They all have their unique benefits, and we can talk about that if you’d like. But the sedentary behavior I think is just one of the most more shocking ones that people just may not know about Cheryl McColgan (10:18)Yes, totally agree with that statement from just getting moving because I think like I said before, people think they go to the gym and that’s good enough. That’s not that’s not the end of the story. But you did touch on one I would like to maybe chat about a little bit more. And that was the use of exercise maybe in a different way. So I was very focused on fasting for a while when Dr. Urashimo I’m going to mess up his name. I’ll put it in the show notes. But you know, when they first kind of discovered a Toshi back in 2016, and I learned about fast. Christo (10:35)Yeah. You Cheryl McColgan (10:47)And I was very focused on that for a while. But now that I’ve gotten older, my bigger concern is maintaining muscle mass as I get over the age of 50. And so I’ve kind of stopped that because I also learned that exercise actually promotes autophagy really strongly. And maybe I’ll just have you actually talk about autophagy in a more scientific way so that people understand its relation to cancer. So maybe if you could talk about that with exercise, that would be awesome. Christo (11:13)Yeah, so I think how I relate this is something called myokines. When we exercise, you get our bodies moving and our muscles are contracting, they release something called myokines into the bloodstream. The simple answer is myokines are anti-cancer proteins. And the more we contract our muscles, the more these anti-cancer agents are moving around our bloodstream and not only are we able to more effectively kill cancer cells, it is something that’s going to promote, really just promote overall health in general, not just cancer, but everything else as well. There’s actually a recent study in 2025 about breast cancer, it’s out of Oxford, I believe, and they talk specifically about these myokines, and it was something Don’t quote me exactly on the number, but it was just one bout of vigorous intensity activity. It increased their blood circulating myokines by like up to 30 % and they exposed those myokines to breast cancer cells. And actually that number, the rate of growth was reduced by 30%. So it just goes to show how effective muscle contraction and movement is in the anti-cancer in our body’s ability to fight cancer off. Cheryl McColgan (12:35)Yeah, I will share. And I mean, again, not to bring it back to the but I think it’s really relevant to what you’re saying is I mentioned that my dad was kind of in the running boom and he had always lifted weight. He was like Jack Lilley basically, which was why it was such a shock that this but anyway, when he got this more serious diagnosis of cancer, I’m really convinced that the reason he did so well for so long was because every time he did a treatment, he got right back to his three days a week strength training, running, playing golf, super active, never let that go. Christo (12:45)⁓ wonderful. Yeah. Absolutely. Cheryl McColgan (13:04)for the longest Christo (13:04)Yeah. Cheryl McColgan (13:05)time. And so I think that that actually helped not only helped his quality of life while he was living with cancer, but also probably got him further down the road. I really think that’s true. Christo (13:11)Yeah. 100%, there is so much robust science about this. a lot of, you of course, after something gets a diagnosis of cancer, of course, your body’s going through changes and it is even more difficult to get up and get moving, going to gym and doing those things. So kudos to your father and anyone else who has gone through that to make sure they’re giving their body the exercise they need because it’s not only It’s exercise is not just a ⁓ healthy lifestyle modification. It’s an actual biological intervention that helps fight cancer. Like it is proven. It is not just, it’s not a replacement for your chemotherapies and your surgeries and whatnot, but it absolutely reduces your risk of getting cancer. It improves your survival if you do get cancer. and there is only benefits from this. So this is just a really hard point to make that exercise is proven to improve your survival in a number of different ways. We’re talking about cancer today, but there’s a number of other things as well. Cheryl McColgan (14:28)it’s pretty much the cure for everything, right? If you really want to look at it, it is. Yes. Christo (14:30)It is. It is. And it’s free. It’s free. We can all do it. You know? Yeah. Cheryl McColgan (14:36)I know it’s very exciting. Well, most of us, know, thankfully. So on that note, there is, I think I’d be remiss not to at least mention this and maybe get your thoughts on this. Because as you said, you’re in the operating rooms, you’ve seen all these different kinds of cancer. Have any of your colleagues or you yourself had any thoughts on the significant rise of colon cancer in young people? ⁓ Are we thinking processed food? Are we thinking other lifestyle factors? Kind of what’s your sense of it after being in the trenches with that? Christo (14:57)Yeah. Yeah, yeah, very astute question because that’s actually the statistic I believe is colorectal cancer is the only cancer that is rising in people under the age of 50. And more recently, you know, this is early 2026, James Vanderbeek passed away, which a lot of us know from like Dawson’s Creek and you know, other movies. and Chadwick Boseman, another big time actor, and they both passed away from colorectal cancer at young ages. And sometimes it’s a difficult pill to swallow when these people, you know, we don’t know them, but they’re part of our formative years. And the good thing about, and I don’t say good thing, but maybe the positive silver lining is it’s bringing awareness to people that this is something. Now, do we know why colorectal cancer is increasing in this specific age group? No. As you alluded to, could very well be what’s environmental exposures and I’m not saying this specifically to those gentlemen, but it can be a number of things. We don’t know the exact answer. We do know there’s a lot of different risk factors for colorectal cancer that a lot of people do have and it’s present in our nutrition system and how the United States is kind of set up. And it’s a lot of processed foods, it’s processed meats, it’s adiposity when you’re carrying some extra weight and obesity, being overweight, all of those things play a role into cancer. Real briefly, this is something that I think a lot of people may not know, but obesity itself is a chronic form of low-grade inflammation, okay? So your body is under this chronic inflammatory state when you have obesity. And the reason that’s important is because when we have bodily inflammation, that increases the risk for mutations in our DNA, in our cells, and that’s exactly how cancers can arise. Cheryl McColgan (17:11)So would that mean also, I think the most common marker that people probably get when they go to their annual checkup is an HSCRP, which is kind of a marker of general inflammation in the body. So would it be accurate to say that if you have a higher HSCRP that you are probably slightly more at risk for cancers and that would be a thing to maybe consider trying to actively lower? Christo (17:19)Mm-hmm. Yeah, so CRP is one of the, ⁓ C-reactive protein is one of the markers for inflammation. There are a number of other ones, cortisol being ⁓ another big one. I don’t wanna say, I don’t wanna say for certain that yes, that is, that’s true, because our body undergoes inflammation. Rewind a second. When you get a lab ⁓ test done, that is one point in time. Right, it’s that day. So it’s hard, you’re not gonna be testing your CRP every single day to know are you always under the same state of inflammation. That being said, your body undergoes inflammation for a number of reasons. And sometimes inflammation isn’t bad. Sometimes it’s reactive and appropriate for what we’re doing. But yes, in the general sense, if you have… maybe like dietary inflammation, if your body isn’t sleeping properly and your body’s in a general state that’s heightened for inflammation, then yes, those kinds of things on a long-term basis are more what we’re aiming for here. One lab test, it depends. It can be a number of different things. There’s also a lot of… different medical states and conditions that can increase your CRP. So it’s not always like a perfect marker. It may be a clue and your healthcare provider can kind of clue you in to like put the whole picture together, but every individual is very different. And as I said, it’s kind of a one marker in time. So lab tests can be helpful, but it’s just not the end all be all. Cheryl McColgan (19:06)Yeah, understood. Just kind of wondered if there was any association there. And you mentioned one of my favorite words when you were just answering that question, that is sleep. I think it’s one of the most underappreciated health. elixirs basically for people and that so many people struggle with it. ⁓ But how would you describe sleep’s relation to cancer? I know a lot of the stuff about sleep’s relation to possible Alzheimer’s prevention, but I haven’t necessarily heard as much about cancer, so I’d love to hear your views on that. Christo (19:18)Yes. yeah. Yeah. Yeah. Yeah. Yeah, yeah, absolutely. So there’s a couple of things to know regarding sleep and cancer. And I’m gonna draw back a discussion I had with a patient where they were like, I’m exercising all the time, I’m eating well, I’m getting all my minute guidelines, my stress is well managed. And then you dive a little bit deeper and they’re like, oh, I only sleep four or five hours of night. And I’m like, oh, why are you doing that? Well, you know, they’re crazy busy. They’re always productive. And we kind of take a step back and get more of a clue of, you know, the whole picture of that patient. And it was telling because as you mentioned, sleep, a lot of people, we almost treat it as an afterthought. You know, it’s at the end of the day, we kind of get in our beds and go. However, sleep is so critical for our overall health that it really needs to get more of a bright light on it because it’s that important. And the relationship to cancer is actually, it’s very clear and I’ll tell you why. At night, throughout the day, 24 hours, your body is always undergoing maintenance. Your body’s always fixing damaged DNA, fixing cells that are damaged for whatever reason and we’re repairing them or we’re scheduling them for apoptosis and getting them out of our bodies. Now that happens all 24 hours, but it’s way more active when we’re sleeping. It’s when the maintenance workers of our body are going to work and that happens at night. So if you’re not getting enough sleep, we are, or quality sleep. We are not restoring, we’re not repairing those DNA in the cells and those mutations. It’s almost like a glitch in the system where these mutations occur and then they live on and they thrive. the more and more those mutations grow, that’s when you get a tumor. So when we don’t get that sleep at night, our maintenance workers aren’t working and those mutations kind of can grow into cancer more easily. Cheryl McColgan (21:43)Yeah, that makes perfect sense. And what would you what would your advice be to people? I mean, I’ve written about this a lot. So there’s some free resources on my website for better sleep. And I do all the things I am committed to sleep. You know, I have the cooling bed, the cooling bed, the dark room, the I like everything. So there’s all those kind of tips. But if somebody wants to do something without devices, and without drugs in particular, I think that people Christo (21:53)Awesome. Yeah. Yeah. Yes. Sure. Yeah. Cheryl McColgan (22:08)I’d love to hear your perspective on that and kind of what are some more natural ways people can approach doing this that aren’t devices that don’t cost a lot of extra money. Christo (22:11)Yeah. Yeah, yeah, yeah, we can talk a lot about this. think it’s actually, ironically, it’s sleep awareness week right now. So it’s, ⁓ yeah, it’s a big topic right now. So what can you do? So you mentioned a lot of things regarding sleep environment, where you’re sleeping in a cool, dark place, cool, dark and quiet place, not silent, but quiet. And a lot of people focus on that, which is really good. Cheryl McColgan (22:23)Nice. Christo (22:40)But something that people may not know is what we do during the day matters very much how good quality of sleep we get at night. And this is not going to be a shocker, but one of the best activities that you can do during the day to get more quality sleep, a higher level of deep sleep, is exercise. exercise really is just a panacea for everything. ⁓ But the reason being is when you exercise, your body’s obviously working a lot harder and its body temperature goes up. Well, a few hours after, your body temperature starts to cool down and that’s exactly what we would like for sleep. So it’s just something that every single day we wanna incorporate some sort of exercise for that. And there are a number of other things like the three two one zero rule if you’ve heard of that or we could talk about that. ⁓ Cheryl McColgan (23:39)Yeah, I’m not familiar with that one. So I’d love it if you’d share that Christo (23:41)Yes, yeah, yeah, the three, two, one, zero rule. It’s something easy to remember because of the numbers, but three hours before bed, you don’t have any more food. Are you able to do a light snack? Sure. But you don’t want to have your dinner too close to bedtime. You want to give your body enough time for digestion. If you’re eating too close to meals, excuse me, too close to bedtime, you can have indigestion. You can have a number of different things that can cause disruption to your sleep. Two hours before bed, no work or no stimulation. You really want to, yeah, I know, I’m a culprit of this. It is, it is. It’s one of those things where I’m like, what’s the phrase? ⁓ Don’t do as I say. Yes, that’s it. Yep, so I’m a bad one on that, because I’m a workaholic. But yes, no more work two hours before bed. And it’s really just trying to unwind and kind of decrease your stimulation. That’s the real reason. Cheryl McColgan (24:13)That’s a hard one. Do as I say, not as I do. Christo (24:38)One hour before bed, no screen time. And this is something where I say, mean it, no screen time. Blue, I talked to a sleep medicine doctor last year or so, and she’s a great friend of mine. And she just says, how many people are, we’re all so glued to our phones. And not only that, it’s like a fifth appendage where we’re sleeping, it’s right next to our beds. And the, one of the best tips that she gave me was, to use an actual alarm clock. Get that phone away from your bed. You don’t need it when you’re in the bedroom. It’s, know, emergencies happen and whatnot, so you can have it somewhere nearby, but it doesn’t need to be an arm’s length. anyway, no screen time after one hour before bed. And then the zero is a little bit different. It’s the number of snoozes were allowed, or ideally allowed, zero. Cheryl McColgan (25:34)you Christo (25:36)And that really focuses on having a consistent wake time. And that’s even something that we wanna do on our days off from work. And the reason being actually does relate to one of the risk factors for cancer is circadian rhythm disruption. If you have a consistent wake time, your body is just much happier. it works more efficiently. The nighttime maintenance things that we talked about are more, just work better. And you really, you keep that wake time and then if you have to adjust your bedtime, you adjust your bedtime to something earlier. But a consistent wake time is something that is a forever rule of thumb if we’re able to. Cheryl McColgan (26:21)Well good, I’ve got to work on the zero and the two probably a little bit for myself. ⁓ Christo (26:27)Yeah, yes, none of us are going to be perfect at this. An 80-20 rule, try to aim for 80 % of these, 20%, give yourself some grace. Cheryl McColgan (26:36)Yes, progress over perfection, one of my favorite things. So ⁓ one thing that we didn’t hit on yet that I think is fairly important for cancer stuff, and I think it’s, it’s good because there’s a trend, there’s a downward trend in alcohol consumption, I think since the pandemic, basically. And I think everyone has always known that alcohol consumption is related to cancer, but somehow it wasn’t being driven home as much as it has maybe the last Christo (26:39)Yes, exactly. Yeah. Yeah. Mm-hmm. Yeah. Cheryl McColgan (27:06)five to 10 years. So we’d just love to get your thoughts on that. mean, nobody wants to hear this if you like, you know, having a glass of wine with your steak or something like that. But, but I think, you know, minimizing these things, like we’re talking about minimizing environmental exposures, maximizing sleep, I mean, can we talk a little bit about it? Because it’s going to be unpopular, but it is a thing. Christo (27:08)Yeah. Yeah. Yeah. Yeah. Yeah. Yeah. So I try to tiptoe just to be gentle with this because people do have strong feelings like I want my red wine at night and you can’t convince me otherwise. There’s a lot of topics to talk about. There’s a lot of discussion points. The plain answer here is no amount of alcohol is Cheryl McColgan (27:28)you Christo (27:44)helpful for your health, okay? So there’s no benefit to it. Some people who drink red wine say there’s, you know, the, my God, nitro, it’s skipping my, yes, Reservatrol, yes, thank you so much. Is helpful for you, yes, it is, but so are having a handful of grapes and you don’t have to have it in a wine form. ⁓ So there’s, Cheryl McColgan (27:52)Reservitrol. I think I read that to get enough Reservatrol, you’d have to drink like 25 barrels of wine or something to get so it’s like, it’s not even a thing. Christo (28:08)Exactly. Yeah. It’s one of those reasons that Hawaiian connoisseurs are like, yeah, well, it’s fine. I’m one of those people where you have to enjoy life too. it’s, you know, take everything with a grain of salt. But yeah. And then a lot of people actually bring up like the blue zones. Have you heard of the blue zones before? Yeah. Perfect. So blue zones, one of the discussion points Cheryl McColgan (28:27)Absolutely. Yeah, we talked about it a little bit on the podcast. Christo (28:35)is having red wine in moderation during meals when you’re socializing. So when you’re watching Netflix having a bottle of red wine, it’s not the same as having a glass of wine slowly over a couple hours with dinner socializing, which is a protective factor for your health. So it’s a little bit different. It’s kind of a scenario. ⁓ but yeah, they used to kind of say two drinks for men, one drink for women per day. That’s, that’s changed. There’s another, the most recent administration came out with new dietary guidelines, for Americans just maybe a month ago or so. lots of talking points there. We won’t go too into that, but there is one regarding alcohol and they They kind of, I’m trying to word this correctly, they said enjoying some alcohol in moderation isn’t advised, but it’s it’s okay to do, which I think where they’re coming from with that is trying to have social connections, it’s a, because the reality is a lot of people do enjoy alcohol together and it brings people together and there are, health benefits to that. The alcohol standpoint, as I said, no organizations recommend any healthy amount of alcohol, but there is something to be said about enjoying your life and having social connections and bringing people together. And I think that is positive. I think they at least nailed that part for sure. Yeah. Cheryl McColgan (30:13)Yeah, and I would agree with you that I think that that having traveled extensively in the Mediterranean that that is where, you know, there’s a lot of issues with those Blue Zone studies, right? We don’t need to go into all that today. But I think that the one that probably everybody can agree on is the importance of community and support systems and the amount of movement that all of those zones get. They’re very active. They have this great support and connection and they have this community that a lot of other places in the world don’t have. So whatever you think about their diet or their wine consumption or Christo (30:24)Yes, yeah. Yeah. 100%. Yeah, yeah, yeah. Cheryl McColgan (30:43)of that I think that we can agree on the rest of it for sure. Christo (30:47)Yeah, you’re nailing it on the head because when we have these discussions, if you see these other very in-depth evidence-based discussions online, we’re really zooming in on one little thing. And the reality is it’s the totality of our lifestyle that affects our health outcomes. Having a glass of wine, I’m not gonna say don’t do it. But what’s the rest of your health look like? What’s rest of your lifestyle look like? We have to be reasonable about it and not getting a good night’s sleep here and there, no big deal. But if it’s a consistent chronic issue, sure, then you address something. But a lot of us have the idea of any 20 or progress over perfection. It’s just the idea of trying to do our best to improve and giving ourselves some grace. as we alluded to way back when, in the beginning of this conversation, what we’re doing right now for most people in this country, we’re not successful with our health. We just simply aren’t. And so we have to start addressing these issues more head on and figuring out what can we start changing? And that kind of brings up another point. A lot of us know what’s healthy. We know what’s healthy, but we’re not so good at how to make effective change and how to keep those change long, you know, as a sustainable habits for ourselves. And I think that’s something that we could all kind of work on, especially the health and fitness professionals teaching people how to do those things. Cheryl McColgan (32:26)Yeah, that’s that’s one of the huge focuses of my work is to have my background in psychology. So the whole habit change is something that’s been a very long time interest of mine. And so it’s Yeah. So since you brought Thank you. Yeah. Since you brought that up, I want to be respectful of your time. But I think just one final one final actionable thing that we could have here is in you. Like you said, you’ve been a personal trainer, your lifestyle, medicine, doctor, that probably is the biggest challenge for me. I think everybody at this point Christo (32:32)⁓ yes. Yeah, I saw the 30 day challenge too. Love it. Love it. No, it’s okay. Cheryl McColgan (32:56)they should be doing, they know they should be moving more, know they should be eating better, they know they shouldn’t be drinking too much, but at the execution of it. So what would be your best tips for people on how to actually make changes in your experience? Like what’s been the most successful? Christo (32:59)Yeah. Yeah. Mmm. Yeah, really good question. So I am a big proponent of utilizing the current routines you have and adding on to them. It’s a lot harder to start something brand new. So if you’re able to, so say in the morning you already, you you brush your teeth, you wash your face. Well, you know, start adding in healthy habits to that existing routine and do that. Most habits take a. The science says 66 days if you’re doing it every single day. It’s really about the repetition. And our brains, they’re neuroplastic. So we can learn to do these things. We can be successful in them. The idea is just making sure we do them repetitively enough that it sticks. Just like swinging a baseball bat and learning how to play baseball or work on the computer and getting better at typing or whatever analogy you wanna use. We can do that with our lifestyle as well. And I think most of us have some sort of routines already. So we wanna kinda zoom out, look at our routines. What can you add into that routine that’s going to improve your health? What are you trying to improve? And once you kinda get that awareness, you’re able to add something in. Do it every single day. I use the rule of twos. I kinda made this up, but for two months, do a new habit for two months. without missing two consecutive days. And that is something that kind of, again, points to the consistency repetition. And then once you get that, add onto it. Start small and build up, and over time, you’re gonna have this considerable change that’s gonna be really, make a big impact on your health. Yeah. Cheryl McColgan (34:51)Yeah, I love that two days rule because part of that you mentioned the 30 day challenge part of it was like not making people overly stressed about it like hey, if you miss a day, it’s fine. But the challenge with that is it’s okay to miss a day, but you don’t want to miss like two, three, four, then all of a sudden, it’s not a habit anymore. So I love that just don’t miss two days in a row. That’s very good. Christo (34:59)Yes. Yeah, exactly. Yeah, easy to remember. Cheryl McColgan (35:11)so we’ve covered some awesome information today. And I’m really excited for people to connect with you. Can you share your website, tell them about some of the programs we talked about before we have for professionals for regular folks, what are all the good things that people can learn from you? Christo (35:25)Yeah, absolutely. So atlasmd360.com, it has a bunch of resources, a of free resources as well. You can do a health audit assessment, you can take some quizzes, there’s a free 30 minute course, there are free resources on how to improve your ⁓ heart lab work, and a bunch of other things. And if you are a professional looking for continuing education, There are approved accredited programs for health and wellness coaches, personal trainers, and AMA category one credits for a bunch of physicians and NPs and PAs. And then if you are non-professional and you’re looking to improve any part of your lifestyle, there are programs for you as well. But overall, we have a lot of free resources and I just, hope when I these podcasts, I honestly just hope One person learned something good that they can take away from this and make some positive difference. Cheryl McColgan (36:23)Well, Dr. Frangopoulos, I have no doubt whatsoever that people learned way more than one thing in this conversation. And I just want to thank you for sharing your time and knowledge today. So I appreciate it. Christo (36:28)I hope so. I hope so. Thank you Cheryl for having me. I appreciate it and I’m loving what you’re doing so keep it up. It’s awesome. Cheryl McColgan (36:39)Thank you.
In this episode of the HealthspanMD Podcast, Dr. Robert Todd Hurst, MD, FACC, FASE sits down with Dr. Du Mond to explore a critically overlooked driver of cardiovascular disease, brain health decline, and chronic inflammation: the mouth. They dive into the powerful connection between oral pathogens and systemic inflammation, the role of red complex bacteria in heart disease and Alzheimer's risk, how saliva testing can uncover hidden inflammatory triggers, and why simply brushing and flossing may not be enough. If you've optimized your diet, exercise, and labs but your inflammatory markers like HSCRP or Lp-PLA2 remain elevated, this conversation may uncover the missing link. About the Guest Dr. Du Mond is a dentist with advanced expertise in oral systemic disease, pathogen testing, laser dentistry, ozone therapy, and immune-informed treatment planning. She approaches oral health not as a cosmetic issue, but as a foundational pillar of longevity, cardiovascular prevention, metabolic health, and neuroprotection. By combining CBCT imaging, salivary pathogen testing, and immune profiling, she helps identify hidden sources of inflammation that traditional dentistry often overlooks.
Liver Boost from MSW Nutrition is designed to support phase 1 and phase 2 detoxification pathways — the exact processes your liver uses to metabolize and clear estrogen. During perimenopause, when hormone levels fluctuate and detox pathways can become sluggish, supporting liver function is foundational. Liver Boost helps your body process hormones more efficiently, which can ease bloating, mood swings, skin changes, and stubborn weight fluctuations discussed throughout this episode.
What does real longevity actually look like? Is it the latest biohacking trend, or something much more foundational? In this episode, I sit down with Dr. Loren Marks, chiropractor and longevity-focused clinician, to discuss why the conversation around healthspan is rapidly becoming one of the most important topics in modern healthcare. Together, we explore how true longevity is less about chasing health fads and more about understanding and optimizing the body's fundamental physiological processes. Dr. Marks breaks down the difference between biohacking and sustainable longevity, emphasizing the importance of metabolic health, inflammation control, and personalized assessments. We discuss key biomarkers such as insulin and hsCRP, the role of muscle mass in aging well, and why balance training is one of the most overlooked strategies for preventing falls and maintaining independence later in life. If longevity is the healthcare conversation of the next decade, this episode offers a clear roadmap for practitioners and patients alike. From foundational metabolic markers to functional movement and personalized care, we explore how integrating modern science with clinical fundamentals can help people not just live longer, but live better. Key takeaways: Longevity is rooted in physiological optimization rather than quick-fix biohacking techniques. Metabolic markers such as insulin, APOB, and HSCRP play crucial roles in determining health risks and should be part of regular health assessments. Muscle mass is pivotal for glucose disposal, fall prevention, and overall health, making strength training essential for longevity. Balance training can significantly reduce fall risks, a leading cause of serious injuries among older adults. More About Dr. Loren Marks: Dr. Loren Marks is a Manhattan-based Doctor of Chiropractic and board-certified Clinical Nutritionist with more than four decades of clinical experience guiding patients toward precision health, structural integrity, and long-term vitality. At his Midtown practice, Dr. Marks delivers executive-level health optimization through comprehensive metabolic analysis, advanced cardiovascular risk stratification, microbiome and gastrointestinal evaluation, hormone mapping, and precision structural care. His work integrates chiropractic medicine, functional nutrition, advanced blood chemistry interpretation, and non-invasive performance technologies into a cohesive, data-driven model of care. With a deep foundation in spinal biomechanics and neurophysiology, Dr. Marks brings extensive expertise in structural rehabilitation, chronic pain syndromes, neurologic function, and the relationship between biomechanical alignment and systemic health. His clinical approach recognizes that metabolic resilience, neurologic integrity, and structural stability are inseparable components of long-term performance and longevity. Dr. Marks is the author of a chapter in Arachnoiditis: The Evidence Revealed, edited by Antonio Aldrete, MD, and a contributing chapter author in Integrative Gastroenterology, edited by Gerard Mullin, MD, as part of the Andrew Weil integrative medicine series. His published work reflects a longstanding commitment to bridging structural medicine, gastrointestinal health, and systems-based clinical strategy. Known for synthesizing complex laboratory and clinical data into clear, strategic action plans, Dr. Marks focuses on identifying subtle patterns of dysfunction years before they manifest as overt disease. His philosophy is grounded in a core principle: sustainable longevity and peak performance are achieved not through isolated interventions, but through system-wide alignment — metabolic, neurologic, structural, and behavioral. Dr. Marks provides discreet, highly personalized care for individuals committed to measurable, evidence-informed health optimization. Licensed Doctor of Chiropractic in New York State. Board-Certified in Clinical Nutrition (DACBN). Website Instagram Connect with me! Website Instagram Facebook YouTube
Fatty liver affects 1 in 4 people worldwide, yet most don't know they have it. In this episode, we break down what fatty liver is, why it's connected to energy, blood sugar, inflammation, and long-term health, and walk through 5 science-backed steps to start improving it — from cutting processed foods and fasting to targeted supplements, gut repair, and the labs you need to track your progress. FEATURED PRODUCT Liver Boost by MSW Nutrition combines 15+ liver-supporting ingredients — including NAC, milk thistle, alpha-lipoic acid, turmeric, green tea extract, DIM, broccoli extract, and resveratrol — designed to nourish and support liver function while you work on the dietary and lifestyle changes discussed in this episode. When fatty liver means your liver is malnourished and overloaded, Liver Boost delivers the targeted nutrients research shows can help reduce oxidative stress, support detoxification, and promote the liver's natural regenerative capacity.
Science of Spirituality PodcastFIVE PRIMARY POINTS of the PODCAST1. Why We Choke Under PressureChoking occurs when extreme stakes overload the brain's motor system. Research shows:* Large “jackpot” rewards (e.g., Olympic gold) can push neural activity past the optimal preparation zone.* Explicit monitoring (thinking step-by-step about an automated skill) disrupts fluid performance.* Moderate pressure improves performance, but excessive pressure impairs it.* Choking is often linked more to inadequate preparation than lack of talent.2. Three Science-Based Ways to Reduce Choking* Train under pressure (e.g., videotaped practice) to desensitize anxiety.* Shift attention outward if you're an expert (focus on rhythm, target, counting backward) to let automatic systems run.* Novices should instead focus on one simple cue, not the entire process.* Reframe the stakes — focus on process over outcome to prevent mental overload.3. Olympic Gold Medal Lessons: Team Chemistry & Inner WisdomTwo Olympic examples illustrate vitality principles:* U.S. Hockey Team: Built intentionally for chemistry and grit (“F-150 pickup trucks,” not Ferraris). Cohesion > raw star power.* Alysa Liu (Figure Skating): Won gold after burnout by reclaiming autonomy, joy, and intrinsic motivation. She ignored medal pressure and focused on artistry.Lesson:* Teams win through cohesion and resilience.* Individuals win when they align performance with authentic purpose and joy.4. The Vitality Zones & the 60-Day Vital SprintDr. Mishra introduces four zones:* Vitality Zone (energized, purposeful)* Surviving Zone (functional but unfulfilled)* Sliding Zone (declining habits)* Burnout Zone (exhausted, depleted)The 60-day sprint focuses on improving:* Physical vitality (exercise, sleep regularity, proprioception, inflammation control)* Mental vitality (focus training, limiting mind wandering)* Social vitality (cultivating closeness)* Spiritual vitality (serving something larger than oneself)5. Core Vitality Levers Backed by DataKey evidence-based takeaways:* 15–20 minutes of daily exercise reduces mortality and inflammation.* Sleep regularity may matter more than duration.* hsCRP (inflammation marker) may predict heart disease better than cholesterol.* Two to three cups of caffeinated coffee or tea daily are linked to lower dementia risk.* A wandering mind reduces happiness; focused attention increases well-being.* Purpose and closeness are modifiable assets strongly tied to longevity.* Spirituality (belief in something larger than self) supports mental health.Elite execution requires preparation, calibrated pressure, authentic motivation, and alignment across physical, mental, social, and spiritual domains.Dare to Be Vital. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit vitalityexplorers.substack.com/subscribe
Discover the five scientifically-backed root causes driving autoimmune disorders that traditional medicine overlooks. From vitamin D deficiency and gut damage to hidden infections, antioxidant depletion, and chronic stress—learn the framework for understanding what's really happening in your body and where to start your healing journey. (494 characters) SEO Keyword: root causes of autoimmune disorders FEATURED PRODUCT Zen – Bovine Adrenal Support When your body is battling an autoimmune disorder, your adrenal glands are working overtime to produce cortisol and combat inflammation. Zen features bovine adrenal gland extracts designed to support adrenal function, helping your body manage stress responses and maintain energy levels—critical factors when addressing the chronic stress patterns that contribute to autoimmune development and flare-ups discussed in this episode.
Broadcast from KSQD, Santa Cruz on 1-29-2026: An emailer asks about hemorrhoids affecting 2 relatives,a 60-year-old man and his 20-year-old daughter, with the daughter also experiencing constipation worsened by fiber supplements. Dr. Dawn explains hemorrhoids are essentially varicose veins of the anus, with 102 genetic regions identified affecting blood vessel and smooth muscle strength. She emphasizes that fiber supplements without adequate water create "cement in the pipe"—recommending 16-24 ounces of water with supplements and 2 liters of clear water daily. Miralax also requires sufficient hydration to work. Key strategies include exercise to stimulate gut motility, staying off the toilet if unable to produce results, using a standing desk to reduce prolonged sitting pressure, and triggering the gastrocolic reflex by eating. Dr. Dawn discusses research on the "volatilome"—volatile organic compounds in breath that reflect gut microbiome composition. Researchers using sterile mice colonized with specific bacteria could identify bacterial fingerprints through breath analysis. The technique identified disease-associated compounds for tuberculosis and malaria, and correlated specific gut bacteria with asthma severity in children. The research suggests breath testing could eventually replace stool samples for microbiome assessment and disease screening. She explains detoxification biochemistry, distinguishing between water-soluble toxins easily filtered by kidneys and fat-soluble toxins requiring liver transformation. Phase one converts fat-soluble molecules into reactive intermediates—dangerous if they linger—while phase two attaches water-soluble molecules like glutathione to neutralize them for excretion. Supporting phase two requires green tea, cruciferous vegetables, garlic, and curcumin. She cautions against extended fasting for detox, especially over age 50, as it depletes the body's detoxification resources and muscle mass. A caller asks about alkaline versus acidic water. Dr. Dawn explains you cannot alkalinize blood since kidneys maintain pH, but alkaline urine is beneficial. Rather than expensive alkaline waters, adding a pinch of baking soda achieves the same effect. Eating a 3:1 ratio of fruits, vegetables, and grains to animal products naturally alkalinizes urine. She notes lemons paradoxically alkalinize because kidneys overcompensate for the acid load. A caller asks about managing heart disease after receiving a third stent. Dr. Dawn recommends the Mediterranean diet over DASH for cardiac patients, as Mediterranean emphasizes fish, whole grains, and fiber that binds cholesterol for excretion, while DASH focuses on calcium for hypertension. She encourages exploring exercise options through meetup.com groups and the hospital's lifestyle center, emphasizing that consistent effort can reduce biological age by 3-5 years regardless of chronological age.
Get Busy Living PodcastFIVE PRIMARY POINTS of the PODCASTChronic Inflammation is a Powerful Predictor of Disease and DeathDr. Mishra explains that mounting evidence—including a major American College of Cardiology scientific statement—shows inflammation, measured by high-sensitivity C-reactive protein (hsCRP), predicts long-term cardiovascular risk and mortality more strongly than LDL cholesterol alone. Inflammation is no longer a theoretical concern; it is clinically actionable and central to aging, heart disease, cancer, and dementia risk.Excess Inflammation Accelerates Aging and DiseaseWhile inflammation is essential for healing and fighting infection, chronic or excessive inflammation damages tissues and increases mortality risk. Dr. Mishra emphasizes that inflammation may be one of the best biological markers of aging, making immune balance—not suppression—a critical goal for long-term vitality.30-Day Anti-Inflammatory Challenge Targets the Essentials that Matter MostThe episode introduces a simple, actionable “execute on the essentials” framework:cut 200 calories per day, move 20 more minutes daily, sleep 20 more minutes nightly, and strengthen one in-person social connection each week. These small, disciplined changes can meaningfully lower inflammation and reduce disease and death risk without medications.Four Lifestyle Levers—Diet, Exercise, Sleep, and Connection Work SynergisticallyEating less and less often reduces inflammatory burden; regular aerobic and resistance exercise lowers CRP, IL-6, and TNF-α; adequate sleep both reduces inflammation and improves metabolic control; and social connection directly alters immune-related gene activity. Together, these four levers form a powerful, low-cost “anti-inflammatory quartet”Peak Vitality Requires Identifying Your Personal “Free Solo”Inspired by Alex Honnold's rope-free climb of Taipei 101, Dr. Mishra challenges listeners to define their own “Free Solo”—a deeply personal pursuit that demands long-term discipline, courage, and preparation. Pairing biological vitality (low inflammation) with meaningful purpose unlocks the highest levels of performance and fulfillment. Copyright VyVerse, LLC. All Rights Reserved. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit vitalityexplorers.substack.com/subscribe
Send us a textDr. Brandon Crawford is joined by Samuel Shepherd, a former Department of Defense biochemical engineer who used his expertise in weapons development to reverse-engineer a cure for his own "incurable" bone cancer. They deep-dive into the science of oxidative stress, the hierarchy of antioxidants, and the specific molecule that allows animals like naked mole rats and sharks to resist cancer and aging.Samuel recounts his 2003 diagnosis of polycythemia vera, where his blood pressure reached levels that "pegged" medical monitors at 300 mmHg. After years of grueling phlebotomies, Sam used a screening algorithm to find a commonality among cancer-resistant species. That common thread was Astaxanthin. However, he didn't just find a supplement; he discovered a way to modify the molecule into a glucosidic form that bypasses the body's digestive barriers to target disease at the atomic level.Key TakeawaysThe Root of All Evil: 92% of inflammatory disease deaths are driven by the hydroxyl free radical. By neutralizing this specific ROS, you address the cause of disease (the trunk) rather than just the symptoms.Molecular Saponification: By using a glucosidic "Trojan Horse" delivery, astaxanthin enters cancer cells and converts acidic free radicals into alkaline ions, dissolving the cancer cell membrane in seconds.The Antioxidant Cliff: Natural cellular protection (Glutathione, SOD) fails significantly after age 42 W or 50 M, making external supplementation essential for longevity.Beyond Brain Barriers: Unlike many antioxidants, this specialized form of astaxanthin crosses the blood-brain barrier, allowing it to neutralize neurotoxins linked to Parkinson's and Alzheimer's.ResourcesUse code CRAWFORD at checkout on Valasta.net for a discount on your order.Valasta.net (testimonials, NIH research papers, dosing information)NIH Research Database (search: "NIH + astaxanthin + [disease]")ProQuest Government Research DatabaseLife Extension (publishes astaxanthin research papers)Dr. Fred Bisci (mentioned as colleague)HSCRP (high-sensitivity C-reactive protein) testing for inflammation markersHematococcus Pluvialis (algae source of astaxanthin)Products 528 Innovations Lasers NeuroSolution Full Spectrum CBD NeuroSolution Broad Spectrum CBD NeuroSolution Stimpod STEMREGEN® Learn MoreFor more information, resources, and podcast episodes, visit https://tinyurl.com/3ppwdfpm
As 2025 wraps up, it is normal to ask, "What's next for my fertility?" Maybe your cycles felt unpredictable, lab results felt confusing, or you have been living in constant action mode with supplements, protocols, and timelines. In this episode, we slow it down and get intentional. Instead of piling on more, we look at what your body has been signaling and how to enter 2026 with a clear, steady plan using a functional fertility lens. You'll learn: Why pausing at year-end can support ovarian signaling and reduce the stress loop that keeps you stuck How to review 2025 without spiraling, including what helped, what added pressure, and what your symptoms have been communicating Which labs to consider rechecking in 2026 and why they matter for fertility strategy, including TSH, vitamin D, ferritin, hsCRP, AMH, and FSH. The foundation for egg quality support through mitochondria basics, including sleep, protein, minerals, and CoQ10. How to build a realistic nervous system plan that fits a Type A life, so your next step is aligned, not rushed Sarah Clark is the founder of Fab Fertile Inc. and the host of Get Pregnant Naturally. Her team specializes in functional approaches for low AMH, high FSH, diminished ovarian reserve, premature ovarian insufficiency, recurrent miscarriage and helping couples prepare their bodies for pregnancy success naturally or with IVF. This episode is especially for you if: You have low AMH (ng/mL), high FSH, DOR, or POI and want to enter 2026 with a plan that supports your body without adding more overwhelm You have been pushing through and want to make decisions based on insight, not urgency You want a functional fertility approach that connects testing, nutrition, lifestyle, and emotional balance in a practical way Next Steps in Your Fertility Journey Subscribe to Get Pregnant Naturally for evidence-based guidance on functional fertility, and share this episode with anyone on their fertility journey. Not sure where to start? Download our most popular guide: Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH it breaks everything down step by step to help you understand your options and take action For personalized support to improve pregnancy success, book a call here. --- Timestamps 00:00 – Reflecting on fertility as 2025 ends and why slowing down matters 01:05 – Why constant doing and hypervigilance disrupt ovarian signaling 02:10 – Nervous system dysregulation in low AMH, high FSH, DOR, and POI 03:15 – Why rushing into IVF at year-end can backfire 04:40 – Secondary infertility and when fertility issues appear unexpectedly 05:20 – Reviewing what actually helped your energy, sleep, digestion, and mood 06:15 – Supplements vs personalized testing and why guessing adds stress 07:30 – Gut health, thyroid, inflammation, and missed underlying imbalances 08:45 – Retesting labs and focusing on mitochondria and egg quality 10:05 – Choosing your next fertility step intentionally, not from fear --- Resources
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on FGF-23, hsCRP, Cardiovascular Events, and the Benefit of Canagliflozin in the CANVAS Trial.
In this Deep Dive episode of The Trip Lab, we unpack hyperlipidemia (high cholesterol) beyond the oversimplified “LDL bad, HDL good” narrative. We also take a clear-eyed look at the most common concerns people have about statins, what the evidence actually shows, and where these medications fit—and don't fit—within a thoughtful, individualized approach to cardiovascular risk.From there, we explore integrative strategies for managing elevated cholesterol and why, for many patients, lifestyle, metabolic health, and inflammation-targeted interventions may be more effective than medications alone.In this episode, we discuss:Why cholesterol is biologically essential and not inherently pathologicalThe limitations of relying on LDL alone to assess cardiovascular riskHow inflammation, insulin resistance, genetics, hormones, and lifestyle influence lipid metabolismWhen elevated cholesterol truly signals disease—and when it may reflect a compensatory or adaptive responseThe role of advanced markers such as ApoB, Lp(a), hsCRP and CAC scoresWhy risk stratification—not fear-based medicine—should guide clinical decision-makingWhat statins can (and cannot do) and we break down the concerns people have with themWhy integrative approaches (nutrition, exercise, herbal options and mind-body medicine) truly treat the root cause of diseaseThis episode is for clinicians, patients, and anyone looking to move beyond simplistic cholesterol narratives toward a more nuanced, evidence-based understanding of cardiovascular health.
Being told you have Primary Ovarian Insufficiency (POI) or premature menopause can feel like the door has closed on your fertility. But these terms don't mean the same thing and understanding the distinction is essential, especially if you're still hoping to conceive. In this episode, we break down what's actually happening hormonally in each condition, why they're often confused, and how a functional fertility approach can help you understand what may still be possible. You'll learn: The key differences between POI, premature menopause, and early menopause What your labs are really telling you about ovarian function Signs that your ovaries may still be active even if your cycle has stopped Which functional tests give deeper insight into thyroid, immune, gut, and adrenal factors that influence ovarian health How inflammation, autoimmune activity, stress physiology, and nutrient imbalances can drive ovarian shutdown Supportive nutritional, lifestyle, and mind-body strategies that may improve hormone communication and egg health When to combine functional and conventional care to optimize your chances of conception This episode is especially for you if: You've been told you have POI, premature menopause, or early menopause and want clarity about whether your ovaries have truly stopped functioning You're under 45 with irregular or missing cycles, hot flashes, or elevated FSH, and want to understand your next steps from a functional-fertility lens You've felt dismissed or told "it's over," yet you want to explore supportive strategies that may help your hormones and ovaries regain activity, naturally or alongside medical care Next Steps in Your Fertility Journey Subscribe to Get Pregnant Naturally for evidence-based guidance on functional fertility, and share this episode with anyone on their fertility journey. Not sure where to start? Download our most popular guide: Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH it breaks everything down step by step to help you understand your options and take action For personalized support to improve pregnancy success, book a call here. --- Timestamps 00:00 Understanding POI and early menopause and why the distinction changes your fertility options when cycles are irregular or absent. 01:45 What POI before age 40 means and how irregular periods and fluctuating FSH can still indicate remaining ovarian activity. 03:00 Real examples of women with AMH at 0.04 ng/mL and 0.08 ng/mL who conceived by addressing inflammation, gut health, thyroid, and stress patterns. 04:00 How disrupted communication between the brain and ovaries drives POI and the role of autoimmunity, nutrient status, and the nervous system. 05:00 What premature menopause looks like on labs and why confirming ovarian shutdown matters when planning next steps. 06:10 How some women in their forties regain cycles and conceive naturally and what this reveals about hormonal resilience. 08:00 Factors that accelerate ovarian aging, including elevated hsCRP, gut infections, thyroid imbalance, environmental toxins, and nutrient gaps. 09:50 Why the gut and vaginal microbiome influence egg quality and implantation and how hidden infections affect fertility outcomes. 10:50 How functional thyroid ranges guide fertility decisions and why a TSH below 2 mIU/L supports better ovarian signaling and hormone balance. 14:40 Nutrition, mitochondrial support, mineral balance, and mind body work that help improve egg health and ovulation signaling. --- Resources
In this quick update, I break down the newest Phase 3 data for retatrutide, Lilly's investigational triple-agonist medication showing unprecedented results in obesity and knee osteoarthritis. Highlights: Up to 28.7% weight loss (~71 lbs) over 68 weeks 75% reduction in knee pain and major improvements in physical function Cardiometabolic benefits: lower triglycerides, non-HDL cholesterol, hsCRP, and blood pressure We also cover Common side effects and safety signals Perceived excessive weight loss — and what this means for clinical practice in a new era of powerful medications A reality check on Canadian availability (likely 3+ years away) A strong warning about illegal online sales and the risks of buying unregulated products A concise medical breakdown to help you stay informed and safe as the obesity-medicine landscape evolves.
You've been told your AMH is too low or that your egg quality isn't good enough, especially if you're over 40. But AMH doesn't define your fertility; it's a reflection of ovarian reserve, not your ability to conceive. In this episode, we explore how a functional fertility approach can help you uncover the real reasons AMH is low and how to support your eggs, hormones, and body so you can move forward with confidence whether naturally or with IVF. You'll Learn: What AMH really measures and why many women with low AMH still conceive once key systems are supported. The underlying causes that lower AMH: inflammation, gut health, blood-sugar imbalance, thyroid/adrenal dysfunction, and nutrient depletion. Which functional labs reveal what conventional testing often misses (GI-MAP, DUTCH, micronutrients). How to support egg quality after 40 through personalized nutrition, targeted supplements, toxin reduction, and nervous-system regulation. When IVF fits best and how preparing your body 3–6 months in advance can improve response, embryo quality, and implantation. Inspiring success stories, including Samantha (age 44, AMH 0.02 ng/mL), who conceived naturally after addressing gut infections, insulin resistance, and stress. This episode is especially for you if: You've been told your AMH is low and want to understand what that really means for your fertility. You're in your late 30s or 40s and want evidence-based ways to support egg quality naturally. You're unsure if IVF is the next step and want clarity before investing time, money, and hope. Sarah Clark is the founder of Fab Fertile Inc. and the host of Get Pregnant Naturally. Her team specializes in functional approaches for low AMH, high FSH, diminished ovarian reserve, premature ovarian insufficiency, recurrent miscarriage and helping couples prepare their bodies for pregnancy success naturally or with IVF. Next Steps in Your Fertility Journey Subscribe to Get Pregnant Naturally for evidence-based guidance on functional fertility, and share this episode with anyone on their fertility journey. Not sure where to start? Download our most popular guide: Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH it breaks everything down step by step to help you understand your options and take action For personalized support to improve pregnancy success, book a call here. --- TIMESTAMPS 00:00 – What Low AMH Really Means for Fertility → Understanding what anti-Müllerian hormone (AMH) actually measures, and why it doesn't define your pregnancy potential. 02:00 – Why Egg Quality Matters More Than Egg Quantity → How mitochondrial health, inflammation, and hormone balance shape egg potential even with low AMH. 03:30 – Inflammation, Stress, and the Type-A Fertility Pattern → The hidden link between hsCRP, stress, and fertility outcomes in high-achieving women over 40. 05:00 – Functional Team Approach: Beyond Hormones and IVF → How the Fab Fertile Method integrates thyroid, gut, and nervous system insights to improve ovarian reserve and egg health. 07:30 – Gut Health and Fertility Connection → What infections like H. pylori mean for nutrient absorption, estrogen balance, and ovarian function. 09:30 – Blood Sugar, Sleep, and Mood Clues to Hormonal Imbalance → Recognizing insulin resistance and blood-sugar swings as hidden drivers of poor egg quality and disrupted cycles. 11:00 – Foundational Fertility Supplements That Actually Matter → How CoQ10, magnesium, vitamin D3/K2, and methylated prenatals support mitochondria and hormone regulation. 12:00 – Samantha's Story: Natural Conception at 44 with AMH 0.02 ng/mL → A real client case showing how addressing gut, thyroid, and adrenal imbalances made conception possible after repeated loss. 15:00 – Functional Tests That Reveal Why AMH Is Low → The key labs: full thyroid panel, hsCRP, ferritin, insulin, GI-MAP, DUTCH, and nutrient testing to find what's missed in conventional care. 18:00 – Creating a Fertile Environment After 40 → Practical steps to support egg quality, anti-inflammatory diet, toxin reduction, nervous system regulation, and realistic IVF timing. --- RESOURCES
This episode covers: • Cocoa Extract Cuts Heart Deaths A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient. Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm • AI Stethoscope for Home Diagnostics Lapsi Health's Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit. Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com • Beef Organ Supplements Surge Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition. Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com • Spirulina for Collagen and DNA Protection New research highlights spirulina's ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress. Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx • Health Data Privacy Reform A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud. Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025 All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women's hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates Thank you to our sponsors! Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Intro 0:19 – Cocoa Extract & Heart Health 1:52 – AI Digital Stethoscope 3:01 – Beef Organ Supplements 4:24 – Spirulina for Longevity 5:42 – Substack Announcement 6:53 – Health Data Privacy Reform 8:23 – Weekly Upgrade Protocol 9:46 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of the Ancient Health Podcast, Dr. Christopher Motley interviews Chris Burres, a research engineer and entrepreneur, about the groundbreaking molecule ESS-60 and its potential benefits for longevity and supporting your age-related inflammation. They discuss the science behind ESS-60, its mechanism of action at the cellular level, and the importance of olive oil as a carrier. Important note: you can grab a special community discount on some of the products mentioned at myvitalc.com/drmotley with code MOTLEY. Topics Discussed: The molecule that made rats live 90% longer and improved sleep in studies and anecdotally improves skin. HSCRP and Sleep: What's in the works? ESS60 may improve Heart Rate Variability (future research is needed) Issues in the supplement industry ------ Follow Doctor Motley! Instagram: https://www.instagram.com/doctormotley Facebook: https://www.facebook.com/doctormotley/ Website: https://doctormotley.com Follow Chris Burres and his company! Social Media https://www.instagram.com/chrisburres https://www.facebook.com/myvitalc https://www.instagram.com/myvitalc https://www.tiktok.com/@myvitalc https://www.linkedin.com/in/chrisburres https://www.youtube.com/@MyVitalC/videos Book links: https://www.livelongerandbetterbook.com https://www.amazon.com/Live-Longer-Better-Journey-Achievable/dp/B0CFCPVVH3 Podcast LiveBeyondtheNorms Videos for further research Gundry Video: https://www.youtube.com/watch?v=JMNV4yc1598 Jay Campbell Video: https://www.youtube.com/watch?v=gU6ZtGymwec ------ *Do you want to hear more from Dr. Motley on infections, emotions, detoxing the brain and other organs? You can find video courses from his 20+ years of clinical experience and frequent live Q+As. If you want to explore it risk-free for 15 days and bring your questions to his weekly lives you can join here. *If you want to work with Dr. Motley virtually, you can book a discovery call with his team here: https://drmotleyconsulting.com/schedule-1333-7607 * Are you looking for simple, non-invasive sound therapy tools for treating anxiety, or providing balance? You can get $100 off a WAVwatch with the code DRMOTLEY: www.wavwatch.com/doctormotley * Want balanced, natural minerals in one shot glass? These plant-based, bioavailable minerals work at the cellular level to support natural detoxification, helping you feel light, clear-headed, and full of energy. Head to www.beamminerals.com/DRMOTLEY and enter code DRMOTLEY for 20% off your mineral replenishment order.
You don't need to spend a fortune on infrared devices to get plenty of infrared light. Check out this fascinating interview with Dr. Roger Seheult, an expert on sunlight and vitamin D, as we discuss the powerful health benefits of sunlight. 0:00 Welcome, Dr. Roger Seheult 4:05 The abscopal effect of light 4:58 What does light do in the body? 10:24 Infrared light and nature 12:06 The Green Heart study 13:45 Infrared light and sleep 21:24 Indoor lighting and your healthPlease join me in welcoming Dr. Roger Seheult, quadruple board-certified in internal medicine, pulmonary diseases, critical care medicine, and sleep medicine. Dr. Seheult shares some fascinating new research about the ability of sunlight to penetrate the human body. It's been previously thought that the sun could only penetrate a few centimeters into our bodies, but recent research has shown that it can penetrate the entire body and can even be measured on the other side. Surprisingly, randomized, placebo-controlled studies have shown that light can affect parts of the body that were not exposed to sunlight. This phenomenon is known as the abscopal effect. This means that mitochondria from one part of the body can communicate with each other and upregulate, even if they are not directly exposed to light. Infrared light can stimulate the mitochondria to produce more melatonin, which can reduce oxidative stress. It's not significantly affected by the atmosphere, so you can get it almost any time of the day. UVB light, which you need to make vitamin D, is more abundant when the sun is at its highest.Green trees, leaves, and grass reflect infrared light. To maximize infrared light absorption, head to green spaces where nature can reflect infrared light back to you!The Green Heart study measured the HSCRP, which correlates with the risk of stroke or heart attack, in residents of south Louisville, Kentucky—a region characterized by concrete and a lack of greenery. Approximately 8,000 trees were planted in a 4-square-mile area, and the HSCRP was remeasured. This resulted in a 13% to 20% average drop in HSCRP, which correlates to a 10% to 15% reduction in stroke and heart attack risk, without any changes in diet or exercise.Dr. Seheult also explains that daytime light exposure helps with sleep by supporting the circadian rhythm, while nighttime light exposure can have an opposite effect.Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any changes to your health regimen or diet before consulting a physician and obtaining a medical examination, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.
Commentary by Dr. Jian'an Wang.
Vidcast: https://www.instagram.com/p/DPa5RHQADaY/Just out. The American College of Cardiology is urging one and all adults and their medical teams to include the test for general body and cardiovascularinflammation in the annual testing battery. That test is the high sensitivity C-Reactive Protein or hsCRP. The hsCRP test measures low grade body inflammation. Elevated test numbers predict the untimely occurrence of heart attacks, strokes, and death due to cardiovascular disease as predictably as bad cholesterol levels even if your cholesterol numbers are excellent.The test results are as simple as 1, 2, 3. Less than 1 mg/L indicates low risk, 1-3 mg/L implies an average risk, and greater than 3 bodes ill for you. If your magic number is above 3, you probably already know why. Here's chart that runs down the list: smoking; overeating with belly bulges; high cholesterol and triglycerides; high blood pressure; gum disease; and infection.The antidotes to get those hsCRP numbers down: exercise; fruits, veggies, and nuts; oily fish; and moderation of your drinking.https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2016/02/18/14/33/a-test-in-context-high-sensitivity-crp#inflammation #cardiovascular #hsCRP #screening #heartattack #stroke
2025 ACC Scientific Statement on Inflammation & Cardiovascular Disease
If you've been told your AMH is “too low” for your age, or that it means your only chance is IVF with high doses of medication, this episode is for you. AMH is not the final word on your fertility it's a marker that should spark deeper investigation. You'll learn: How IVF clinics use AMH to predict drug response and egg retrieval What the research actually says about high vs. mild stimulation for women with low AMH Why no stimulation protocol can improve egg quality The four functional fertility pillars that truly impact outcomes: mitochondria, inflammation, nutrients, and hormones A client story of moving beyond repeated IVF cycles to conceive naturally I'm Sarah Clark, founder of Fab Fertile. For over a decade, my team and I have helped hundreds of couples improve their chances of pregnancy success, whether naturally or through IVF. We specialize in supporting those with low AMH, high FSH, diminished ovarian reserve (DOR), premature ovarian insufficiency (POI), and recurrent pregnancy loss through functional testing and personalized fertility strategies. This episode is especially for you if: You've been told your AMH is too low and that aggressive IVF protocols are your only option You feel stuck in repeated IVF cycles with only minor protocol changes You want to understand how functional fertility strategies can change the environment where eggs are developing Not sure where to start? Download our most popular resource: The Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH. It breaks everything down step by step to help you understand your options and take action. For personalized support to improve pregnancy success, book a call here. --- TIMESTAMPS [00:00:00] Does low AMH really mean IVF is your only option? Most women are told IVF or donor eggs are the only path forward, but AMH is more than a fertility “score.” Here's why it's misunderstood [00:02:00] What IVF protocols are used for low AMH? High-dose meds, mild stimulation, dual stim, and add-ons like DHEA are common. But do they actually improve outcomes? [00:04:30] Why do repeated IVF cycles often fail with low AMH? Many women get stuck in the loop of “protocol tweaks” while underlying health issues go unaddressed [00:05:00] Can IVF improve egg quality? Research shows protocols change egg quantity, not quality, here's why mitochondrial and cellular health matter most [00:07:00] What functional strategies support mitochondria for egg quality? From CoQ10 and omega-3s to sleep and stress balance, these are the foundations of better egg competence [00:09:30] How does stress and nervous system dysregulation affect AMH? Graduate school, 50-hour work weeks, and perfectionism can suppress ovarian function, here's how to spot the signs [00:12:00] Which labs uncover hidden inflammation affecting fertility? Markers like hsCRP and homocysteine reveal systemic inflammation IVF clinics rarely check [00:14:00] Which nutrient deficiencies impact ovarian reserve and embryo health? Vitamin D, ferritin, folate, B12, zinc, magnesium, selenium, subtle gaps can change outcomes [00:17:00] How do thyroid, prolactin, and cortisol influence egg development? Hormonal imbalances upstream are often missed, yet they shape ovulation, luteal support, and implantation [00:21:00] Can you conceive naturally with low AMH? A client with one ovary, endometriosis, and high FSH conceived naturally after addressing digestion, adrenal health, and nutrient absorption --- RESOURCES
Current treatments for heart disease fail to address root causes. Stents and bypass surgery only restore blood flow temporarily without tackling underlying endothelial dysfunction and inflammation driving heart disease Despite their ability to lower cholesterol, statins have limitations. While these drugs lower LDL cholesterol by 25% to 35%, they don't address oxidative damage or rebuild vessel health, leaving underlying inflammatory processes unchanged Excess linoleic acid (LA) from vegetable oils fuels heart disease. Modern diets contain 7.2% LA, as opposed to 2.8% a century ago. This creates mitochondrial dysfunction and dangerous oxidized LDL cholesterol formation Reducing LA intake shows measurable cardiovascular benefits. Limiting LA to under 5 grams daily reduces inflammatory markers like hsCRP by 15% and IL-6 by 10% within weeks Novel approaches like nanoparticle chelation show promise. Targeted delivery systems can address calcified plaques directly, offering more precise treatment than traditional intravenous methods at lower costs
Dr. Dominic D'Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition.This episode is brought to you by: Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off all mattress orders)Momentous high-quality creatine: https://livemomentous.com/tim (code TIM for up to 35% off)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs)Timestamps:[00:00:00] Start.[00:14:43] Why I'm interested in ketogenic strategies for neurodegenerative prevention.[00:16:18] Mary and Steve Newport's ketone-linked temporary cognitive improvements.[00:18:18] A mechanisms overview for Alzheimer's/dementia.[00:21:25] The immune system as longevity's "fifth horseman" — and why metabolic control is key.[00:22:04] How to measure ketones and GKI.[00:23:00] Fasting vs. ketogenic diet.[00:24:18] There's nothing fishy about sardine fasting.[00:28:32] My hiatal hernia discovery and increased cancer risk concerns.[00:30:04] HSCRP as a superior biomarker to LDL for cardiovascular risk.[00:31:57] Glucose tolerance testing revelations and CGM importance.[00:31:57] Upgrading the metabolic machinery through keto without getting bored.[00:42:07] What do do if you, like Dom and me, are among the 30% who suffer from cholesterol hyperabsorption.[00:43:42] Dom's day-to-day diet regimen.[00:45:56] How Dom optimizes his aging dogs with ketones, SARMs, and supplements.[00:51:30] Supplementing for sleep disruption while fasting.[00:55:41] Why Dom doesn't have misgivings about melatonin.[00:59:15] Shingles prevention through fasting protocols.[01:00:15] Immune system modulation: Innate vs. adaptive, vegan vs. ketogenic.[01:03:54] Dom at 50-something: Current meal timing and composition.[01:05:57] Blue zone observations: Greek and Sardinian longevity habits.[01:08:16] Ketogenic diet initiation tips: MCT, electrolytes, and fasted cardio.[01:15:18] Ketone metabolic therapy for cancer.[01:18:15] The metabolic psychiatry revolution.[01:22:10] The soothing effects of hyperbaric oxygen and ketosis on seizure sufferers.[01:28:27] Metformin vs. berberine.[01:31:43] The low-dose neuroprotective potential of GLP-1 drugs.[01:34:58] NAD research: MIB-626 and stabilized forms for mitochondrial health.[01:39:48] Idebenone, CoQ10, and the Deanna protocol for ALS.[01:42:05] Dom's supplement short list: CoQ10, creatine, ketones, vitamin D, melatonin.[01:44:43] KetoNutrition.org, Metabolic Health Summit, Audacious Nutrition, veteran-focused research protocols, and other parting thoughts.*Show notes for this episode: https://tim.blog/2025/09/03/dr-dominic-dagostino-all-things-ketones/For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
If you're facing low AMH, high FSH, DOR, POI, or recurrent pregnancy loss, this episode is for you. We're diving into hsCRP (high-sensitivity C-reactive protein), a key, often overlooked marker of inflammation, and why it matters for fertility. Learn how chronic inflammation impacts egg quality, implantation, and embryo health, why hsCRP testing is often missed in conventional care, and what functional labs can reveal. We'll also cover homocysteine, ANA, and natural killer cells, plus practical strategies to reduce inflammation and clotting risks for you and your partner. I'm Sarah Clark, founder of Fab Fertile, and for over a decade, my team has helped 100's of couples improve fertility naturally or through IVF using functional testing and personalized strategies. In this episode, you'll learn: Why hsCRP testing is critical yet often overlooked in fertility care How systemic inflammation affects eggs, implantation, embryos, and male fertility Other hidden markers, homocysteine, ANA, NK cells, that can influence fertility outcomes Functional fertility strategies to lower inflammation, including diet, gut health, stress support, supplements, and hormone optimization Real-world case studies showing how addressing inflammation improved fertility, even with low AMH or DOR
If you've had early miscarriage before 12 weeks, especially more than once, and been told everything looks “normal,” or you've been diagnosed with low AMH, high FSH, this episode is for you. We're going to talk about what's often overlooked in early term pregnancy loss: gut health, immune dysfunction, clotting disorders, nutrient deficiencies, and hormone imbalance from a conventional and functional medicine perspective. In this episode, you'll learn: Why progesterone, thyroid function and adrenal health are key to early pregnancy The role of gut dysbiosis, inflammation, and food sensitivities in recurrent miscarriage What comprehensive bloodwork reveals - including homocysteine, hsCRP, ANA, and more Functional strategies to support detoxification, reduce stress, and improve implantation How immune triggers and vaginal microbiome imbalances increase miscarriage risk While the focus of this episode is on the female side of fertility it's not to be overlooked to look at the male partner's health. Poor sperm quality, oxidative stress, gut infections, and DNA fragmentation can all contribute to miscarriage, poor embryo development,t and implantation failure. Just as we look at gut health, inflammation, and functional bloodwork in women,n we need to apply this lens to the male partner. If you haven't looked at semen analysis or functional testing for men, be sure to check out our Male Factor Fertility episode for strategies to optimize sperm health and improve pregnancy outcomes. How To Address Men's Reproductive Health (It's a myth sperm doesn't decline with age!) - https://fabfertile.com/blogs/podcasts/how-to-address-mens-reproductive-health-it-s-a-myth-sperm-doesnt-decline-with-age?_pos=1&_sid=689d505e3&_ss=r This episode is for you if: You have experienced a miscarriage before 12–14 weeks of pregnancy and want to understand what might be behind it. You're seeking both conventional and functional insights to support healing and improve your chances in future pregnancies. You want actionable lifestyle, diet, and testing strategies to help your body prepare for a healthy pregnancy.
Send us a textDr. Michael Koren joins Kevin Geddings to discuss how Knowledge is Power - especially when it comes to medicine. The doctor explains how diagnostic tests like high sensitivity C-reactive protein (HSCRP) empower physicians and patients by giving insight into heart attack and stroke risk. Dr. Koren also tells us that even simple things like knowing you are in a research study can improve patient outcomes, and that knowledge is the guiding principle in medicine.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
In this episode of the RWS Clinician's Corner, Margaret talks with Chris Burres—a scientist, inventor, podcast host, and trained improv comedian—who brings a fresh, accessible perspective to complex chemistry. Chris is the founder of MyVitalC and the driving force behind ESS60, a molecule born from Nobel Prize-winning research, known for delivering the longest lifespan extension ever recorded in lab settings—an astonishing 90%. Margaret and Chris dive deep into the origins and science behind ESS60, exploring its clinical applications, real-world potential, and the crucial red flags to watch out for when sourcing it. In this interview, we discuss: -Unique properties and scientific relevance of ESS60 -Scientific studies and research - with reported improvements in sleep, energy, and focus -ESS60's role in mitochondria and antioxidant capacity -Differences between ESS60 and C60 — quality, sourcing, and background -Manufacturing and natural occurrence of ESS60 -Safety, dosing, and usage guidelines The Clinician's Corner is brought to you by Restorative Wellness Solutions. Follow us: https://www.instagram.com/restorativewellnesssolutions/ Connect with Chris Burres: Website: https://www.myvitalc.com/ Instagram: https://www.instagram.com/myvitalc/ YouTube: https://www.youtube.com/@MyVitalC/featured TikTok: https://www.tiktok.com/@myvitalc MyVitalC Product Offer for RWS community: $15 off coupon with this link: https://www.myvitalc.com/rws/ Get 18 Tips by 50+ Experts Biohacking Tips here: https://www.myvitalc.com/biohacking-tips/ Timestamps: 00:00 From Scientist to Health Advocate 07:28 ESS60: From Toxicity to Longevity 13:41 "Addressing Exercise-Induced Inflammation" 19:14 "ESS60: Shielding Against Cellular Damage" 25:40 Supplement Industry Quality Concerns 27:06 Ensuring Safe C60 Market Entry 33:48 Addressing Anti-Inflammatory Protocols 41:39 Knee Pain Relief Success 43:08 Mitochondrial Health and Complementary Supports 51:41 Distributor's Discovery: Pet-Inspired Product Use 56:38 Impactful C60 Product Testimonial 01:01:19 Training Nutrition Strategy: MCT and ESS 60 01:08:56 "Impact Lives, Share Insights" Speaker bio: Published author, host of the Uncovering the Secrets to Longevity Health Summit, podcast host and patent holder with a surprising twist – he's not just a visionary scientist but also a master of comedy improv. Chris Burres is the founder and chief scientist at MyVitalC, where he manufactures a Nobel Prize winning molecule responsible for the single longest longevity experimental result in history, a full 90% extension of life. He is the intersection where science meets laughter and his life's mission is to help people live longer, healthier, happier, pain-free lives with science. Keywords: ESS60, C60, MyVitalC, mitochondrial health, longevity science, oxidative stress, antioxidants, inflammation, HSCRP, functional health professionals, bioavailability, clinical applications, rat studies, Nobel Prize molecule, supplement safety, research studies, human trials, animal studies, red flags supplements, practitioner protocols, cancer research, mitochondrial buffering, oxidative stress system, glutathione, melatonin, reactive oxygen species, sleep improvement, exercise recovery, supplement industry standards, fullscript integration, practitioner wholesale accounts Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.
Send us a textDr. Trevor Greene joins Dr. Michael Koren to discuss the effects of inflammation on the cardiovascular system. The two cardiologists talk about biomarkers that have increasing importance: including liporprotein(a) and hsCRP. The doctors finish up with actionable lifestyle changes everyone can implement. Koren's Key Takeaways:Inflammation plays a big role in the bodyChronic inflammation influences cardiovascular diseaseThe predictive value of hsCRP is being investigated nowBe a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
The Integrative Cancer Solutions podcast, hosted by Dr. Karlfeldt, introduces Chris Burres, the chief scientist at My Vital C. They discuss a groundbreaking molecule called ESS 60, discovered in 1985 by scientists at Rice University. This molecule, shaped like a soccer ball with 60 carbon atoms, initially found use in industrial applications before its potential health benefits were uncovered. A toxicity study on Wistar rats revealed that ESS 60 extended their lifespan by 90%, shifting focus towards its health applications. Users of the My Vital C product containing ESS 60 report improved mental focus, increased energy, and better sleep. The molecule has shown promise in preventing tumor growth in rats and potentially enhancing the efficacy of anticancer agents. However, it's important to note that while ESS 60 is not claimed to cure cancer, it's suggested as a possible cancer preventative. The manufacturing process for ESS 60 is complex and expensive, involving the vaporization of graphite rods in a vacuum chamber, which emphasizes the importance of high-quality production. The recommended dosage is one teaspoon daily, preferably in the morning, with olive oil serving as a carrier to improve bioavailability. Recent studies have shown that the product can reduce high-sensitivity C-reactive protein (hsCRP) levels in four to six weeks, which is an important indicator of overall health and cancer risk. The company behind My Vital C is committed to ongoing research and transparency, offering different oil options (olive, avocado, and MCT) for consumers and providing additional information through their book, "Live Longer and Better."ESS 60, a molecule discovered in 1985 and shaped like a soccer ball with 60 carbon atoms, has shown potential health benefits including extending the lifespan of rats by 90% in toxicity studies.Users of My Vital C, which contains ESS 60, report improved mental focus, increased energy, and better sleep quality.While not claimed to cure cancer, ESS 60 has demonstrated tumor growth prevention in rats and may enhance the efficacy of anticancer agents.The recommended dosage is one teaspoon daily, preferably in the morning, with olive oil as a carrier to improve bioavailability.Recent studies indicate that the product can reduce high-sensitivity C-reactive protein (hsCRP) levels in 4-6 weeks, which is an important indicator of overall health and cancer risk.----The Cancer Revolution: https://www.amazon.com/s?k=the+cancer+revolution+by+dr.+leigh+connealy+book&crid=2GS09LV93ONK5&sprefix=The+Cancer+Revolution%2Caps%2C199&ref=nb_sb_ss_ts-doa-p_2_21Be Perfectly Healthy: https://www.amazon.com/s?k=be+perfectly+healthy+dr+connealy&crid=30H1M792AF1Q6&sprefix=be+perfectly+healthy%2Caps%2C142&ref=nb_sb_ss_ts-doa-p_1_20----Website: https://www.drrobertwhitfield.com/Youtube: https://www.youtube.com/@breastimplantillnessexpertApple Podcast: https://podcasts.apple.com/us/podcast/explant-breast-surgery-recovery/id1678143554Grab my book A Better Way to Treat Cancer: A Comprehensive Guide to Understanding, Preventing and Most Effectively Treating Our Biggest Health Threat - https://www.amazon.com/dp/B0CM1KKD9X?ref_=pe_3052080_397514860 Unleashing 10X Power: A Revolutionary Approach to Conquering Cancerhttps://store.thekarlfeldtcenter.com/products/unleashing-10x-power-Price: $24.99-100% Off Discount Code: CANCERPODCAST1Healing Within: Unraveling the Emotional Roots of Cancerhttps://store.thekarlfeldtcenter.com/products/healing-within-Price: $24.99-100% Off Discount Code: CANCERPODCAST2----Integrative Cancer Solutions was created to instill hope and empowerment. Other people have been where you are right now and have already done the research for you. Listen to their stories and journeys and apply what they learned to achieve similar outcomes as they have, cancer remission and an even more fullness of life than before the diagnosis. Guests will discuss what therapies, supplements, and practitioners they relied on to beat cancer. Once diagnosed, time is of the essence. This podcast will dramatically reduce your learning curve as you search for your own solution to cancer. To learn more about the cutting-edge integrative cancer therapies Dr. Karlfeldt offer at his center, please visit www.TheKarlfeldtCenter.com
Send us a textCardiologist and research scientist with ENCORE Research Group, Dr. Michael Koren highlights the importance of monitoring your key health numbers with Kevin Geddings. The two talk about the importance of checking weight, cholesterol, and blood pressure, emphasizing consistency in measurement practices for accurate tracking. They discuss newer numbers to check for cardiovascular health, including lipoprotein(a) and hsCRP, a marker for vascular inflammation. Both of these metrics are gaining recognition for their role in long-term heart health.Koren's 3 Key Takeaways:Prevention and early detection are critical to long-term healthConsistency is the key to making sure numbers are accurateClinical research is developing new methods of tracking healthBe a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on AppleWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
Send us a textJoin Dr. Koren and Dr. Ridker for part 2, as they examine the effects of silent inflammation on heart health, emphasizing the importance of understanding specific body signals and the biomarker hsCRP. They also discuss the utility of hsCRP testing as a vital marker for predicting cardiovascular risk due to silent inflammation. The doctors explain how inflammation may play a bigger part in heart disease than many patients - and even some doctors - guess.Koren's Key Takeaways:Inflammation plays a critical part in chronic disease, including heart diseaseMedicine is constantly evolving, bridging the gap between research and practicePatients and physicians have to work together to push science forwardBe a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on AppleWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
In this episode Dr. Paul Ridker discusses the pivotal role of high-sensitivity C-reactive protein (hsCRP), a biomarker for inflammation, in cardiovascular prevention and treatment. He explains how inflammation and cholesterol together drive atherosclerosis, the significance of hsCRP testing, and the latest clinical trial findings. Dr. Ridker also highlights the importance of primary prevention strategies and the potential of targeted anti-inflammatory therapies to revolutionize cardiovascular care.
In this episode, Dr. Brittany Weber discusses the role of inflammation and high-sensitivity CRP (hs-CRP) in cardiovascular disease. She explores the connection between inflammation and atherosclerosis and how immune system activation contributes to atherosclerosis development, the importance of endothelial damage and pro-inflammatory cytokines, and the impact of systemic inflammatory diseases on cardiovascular risk. Tune in to learn about the mechanisms behind inflammation in cardiovascular disease and the significance of hsCRP as a biomarker.
In this episode, Dr. Amir Rezvan hosts a panel discussion with distinguished colleagues Dr. Paul Ridker, Dr. Brendan Everett, Dr. Michael Garshick, and Dr. Kaitlin Voigts Key. The panel explores what high-sensitivity CRP (hs-CRP) is and its normal levels, the role of hsCRP in diagnosing and treating atherosclerotic disease, and how inflammation and hyperlipidemia contribute to cardiovascular events. The panel provides practical advice on measuring hsCRP and interpreting high values. Tune in for this insightful discussion on the importance of hsCRP in preventive cardiology and how to effectively use this biomarker in clinical practice.
In this episode, Dr. Paul Ridker explores the crucial role of inflammation and high-sensitivity CRP (hs-CRP) in cardiovascular health. He discusses the importance of measuring hsCRP and addresses common misconceptions about the variability of this biomarker. Tune in to gain a deeper understanding of how hsCRP can be a powerful tool in predicting and managing cardiovascular health.
After receiving my recent blood test results, I was shocked to see how high my inflammation levels had climbed postpartum. It made me realize just how much our bodies go through during pregnancy, birth, and recovery—and how important it is to take steps toward healing and wellness in those crucial months after delivery. Tune in to learn about my inflammation-reducing strategies, postpartum recovery tips, and more! I TALK ABOUT: 07:00 - Blood testing with SiPhox Health (code: BIOHACKINGBRITTANY) and the importance of biomarkers 10:00 - HSCRP and its importance as a cardiovascular and inflammation marker 18:00 - Symptoms of high inflammation 22:00 - Common root causes of elevated HCRP and inflammation 29:00 - Tips for postpartum physical activity to manage inflammationn 36:00 - Strategies to reduce inflammation: diet, exercise, and sleep 38:00 - Physical exercise benefits and my postpartum workout routine 42:00 - Tips on managing sleep with a new baby 44:00 - Biohacking strategies for inflammation - curcumin, Pendulum Akkermansia, fermented cod liver oil, Tiny Health microbiome testing 49:00 - Sauna therapy and stress management SPONSORS: Save big on BiOptimizers supplements, including my favorites—digestive enzymes, probiotics, and magnesium. Get free gifts for every purchase at the BiOptimizers Black Friday sale this November! Use code BIOHACKINGBRITTANY for the best discount offer! Your smile deserves a glycerin-free and fluoride-free toothpaste from Wellnesse. Use BIOHACKINGBRITTANY for 12% off. RESOURCES: Optimize your preconception health by joining my Baby Steps Course today! Optimize your preconception health and fertility through my free hormone balancing, fertility boosting chocolate recipe! Download it now! My Amazon storefront LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music
If there are 6 root causes to all disease, what can we do to stop them? With 50-60% of Americans on the road to Diabetes, it's clear that our population is sicker than ever. And the harsh truth? We're doing it to ourselves. In the latest episode of The Darin Olien Show, I sit down with Dr. Darshan Shah to explore the common mistakes people make when seeking shortcuts to health, such as opting for advanced medical interventions while neglecting basic dietary and lifestyle habits. We also discuss the six root causes of disease and how to prevent them. Dr. Shah shares insights into the impact of inflammation and high levels of biomarkers like HSCRP and homocysteine, which are often linked to poor gut health and a diet high in glucose and fructose. And practical advice on avoiding sedentary behavior, and prioritizing the right supplementation, nutrition and exercise. Dr. Darshan Shah is the CEO and founder of Next Health, a trailblazer in health optimization. Starting his medical journey at 16, Dr. Shah has seamlessly combined his surgical expertise with an innovative approach to wellness. Under his leadership, Next Health offers advanced, personalized health services, focusing on longevity, vitality, and preventing disease. His vision embodies the fusion of technology and holistic health practices, positioning him as a leading figure in the health revolution. What we discuss… (00:00) - The evolution of medicine towards holistic and individualized health (15:34) - Bio-Optimizing through common sense for longevity and disease prevention (31:17) - The power of small daily habits for longevity (42:51) - Understanding inflammation, and common misconceptions about health eating (51:03) - The 6 root causes of disease and how to prevent them (01:04:32) - Advice on nutritional supplements and incorporating functional medicine …and more! Don't forget: You can order now by heading to darinolien.com/fatal-conveniences-book or order now on Amazon. Thank you to our sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Vivobarefoot: Get 15% off your first order with code DARINV15 at vivobarefoot.com Bite Toothpaste: Go to www.trybite.com and use code DARIN at checkout for 20% off Find more from Darin: Website: https://darinolien.com/ Instagram: https://www.instagram.com/Darinolien/ Book: https://darinolien.com/fatal-conveniences-book/ Down to Earth: https://darinolien.com/down-to-earth/ Find more from Dr. Shah: Website: https://www.drshah.com/next-health Instagram: @darshanshahmd