Sherif Mansour, Head of AI at Atlassian, discusses bridging AI agents with massive-scale enterprise software deployment, drawing insights from Atlassian's millions of non-technical users. He shares his framework for avoiding "AI Slop" using Taste, Knowledge, and Workflow, and explains Atlassian's "Teamwork Graph" for complex enterprise queries beyond RAG. The conversation also explores the evolving relationship between AI and UI, and the shift from humans as workers to architects of AI-driven processes. This episode offers practical wisdom for both AI engineers and business leaders navigating the future of AI-enabled organizations. Sponsors: Framer: Framer is the all-in-one tool to design, iterate, and publish stunning websites with powerful AI features. Start creating for free and use code COGNITIVE to get one free month of Framer Pro at https://framer.com/design Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (03:56) Atlassian's AI Vision (08:27) Trust, Authenticity, and Slop (14:10) Taste, Knowledge, and Workflow (Part 1) (17:33) Sponsors: Framer | Tasklet (20:14) Taste, Knowledge, and Workflow (Part 2) (Part 1) (29:51) Sponsor: Shopify (31:47) Taste, Knowledge, and Workflow (Part 2) (Part 2) (31:48) Technicals: RAG vs. Graphs (40:48) Forgetting, Cost, and Optimization (52:28) The Model Commoditization Debate (55:12) The Future of AI Interfaces (01:02:44) How AI Changes SaaS (01:09:43) Debating the One-Person Unicorn (01:16:17) Becoming a Workflow Architect (01:21:39) The Browser for Work (01:33:23) How Leaders Drive Adoption (01:39:26) Conclusion: Just Go Tinker (01:40:08) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

This deeply personal episode shares how Nathan used AI to navigate his 6-year-old son's cancer diagnosis and treatment journey. He details using GPT-5 Pro, Claude, and Gemini 3 to double-check doctors' decisions, research treatment protocols, plan for potential recurrence scenarios, and handle complex secondary issues like mold remediation during immunosuppression. The episode reveals AI's transformative potential as medical advisors, providing analysis comparable to human doctors while enabling more effective patient advocacy and personalized care planning. Sponsors: Framer: Framer is the all-in-one platform that unifies design, content management, and publishing on a single canvas, now enhanced with powerful AI features. Start creating for free and get a free month of Framer Pro with code COGNITIVE at https://framer.com/design Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) A Son's Diagnosis (06:05) Exponentials & Early Symptoms (13:30) Crisis on Vacation (Part 1) (15:00) Sponsors: Framer | Tasklet (17:41) Crisis on Vacation (Part 2) (24:26) AI's First Intervention (Part 1) (34:34) Sponsor: Shopify (36:31) AI's First Intervention (Part 2) (36:41) Advocating for Answers (47:56) The Scariest Days (59:06) AI as Bedside Co-Pilot (01:11:42) Managing Secondary Risks (01:18:28) Planning for Relapse (01:31:54) AI's Undeniable Value (01:43:02) Rage for Right to Try (02:02:55) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

In this special crossover episode from Beatrice Erkers' Existential Hope podcast, The Cognitive Revolution's host explores the crucial, often-neglected question of building a positive vision for the future in the AI era. The discussion delves into what a new social contract and daily life could look like, covering transformative applications from self-driving cars and personalized tutoring to democratizing access to expertise and radically improving health. Listeners will gain insights into fostering higher societal expectations for progress, understanding Eric Drexler's "comprehensive AI services," and the profound impact of fiction in shaping AI's future. LINKS: Generative deep learning antibiotic design Why Tool AIs become Agent AIs Existential Hope Podcast Sponsors: Google AI Studio: Google AI Studio features a revamped coding experience to turn your ideas into reality faster than ever. Describe your app and Gemini will automatically wire up the right models and APIs for you at https://ai.studio/build Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) Sponsor: Google AI Studio (00:31) About the Episode (02:43) Introducing Nathan Labenz (03:50) A Positive AI Future (Part 1) (12:23) Sponsors: Shopify | Tasklet (15:31) A Positive AI Future (Part 2) (15:31) Excitement for Self-Driving (19:25) Visions for 100 Years (24:58) Near-Term Transformative AI (31:08) AI's Impact on Sectors (41:16) Comprehensive AI Services (52:16) Balancing Hope and Risk (56:51) Raising Societal Ambitions (01:01:30) Branching Sci-Fi Narratives (01:06:00) Lessons From Podcasting (01:09:52) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

Matthew Harvey Sanders, founder and CEO of Long Beard, introduces "Catholic AI," a rapidly growing field serving users in 165 countries. He delves into the philosophical and theological dimensions, discussing the Church's historical perspective on technology, human flourishing, and its stance on AI consciousness and transhumanism, including Pope Francis's insights. The conversation then explores Long Beard's technical innovations, such as training models from scratch for theological alignment, digitizing Vatican archives, and optimizing multilingual models. This episode offers a compelling look at how AI is being tailored to specific value systems, illustrating the orthogonality thesis and instrumental convergence in action. Sponsors: Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (03:16) Building Catholic AI (06:43) The Popes on AI (12:42) A Vision for Flourishing (Part 1) (17:27) Sponsors: Shopify | Tasklet (20:35) A Vision for Flourishing (Part 2) (20:36) Imagining a Post-Work Future (27:21) AI: Tool or Creature? (36:33) Intelligence vs. Sentience (Part 1) (38:10) Sponsor: Linear (39:39) Intelligence vs. Sentience (Part 2) (47:03) Simulation, Faith, and Conversion (51:32) Existential Risk & Antichrist (58:35) The Longbeard Origin Story (01:03:04) Engineering Magisterium AI (01:12:17) Open Source Model Strategy (01:18:34) Longbeard's Business Model (01:23:37) Training a Model From Scratch (01:32:16) Safety, Evals, and Trust (01:39:42) Responsible AI Development (01:48:16) Aligning to Human Flourishing (01:53:46) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

Cameron Berg, Research Director at AE Studio, shares his team's groundbreaking research exploring whether frontier AI systems report subjective experiences. They discovered that prompts inducing self-referential processing consistently lead models to claim consciousness, and a mechanistic study on Llama 3.3 70B revealed that suppressing deception features makes the model *more* likely to report it. This suggests that promoting truth-telling in AIs could reveal a deeper, more complex internal state, a finding Scott Alexander calls "the only exception" to typical AI consciousness discussions. The episode delves into the profound implications for two-way human-AI alignment and the critical need for a precautionary approach to AI consciousness. LINKS: Janus' argument on LLM attention Safety Pretraining arXiv Paper Self-Referential AI Paper Site Self-Referential AI arXiv Paper Judd Rosenblatt's Tweet Thread Cameron Berg's Goodfire Demo Podcast with Milo YouTube Playlist Cameron Berg's LinkedIn Profile Cameron Berg's X Profile AE Studio AI Alignment Sponsors: Framer: Framer is the all-in-one platform that unifies design, content management, and publishing on a single canvas, now enhanced with powerful AI features. Start creating for free and get a free month of Framer Pro with code COGNITIVE at https://framer.com/design Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing

Christopher Alexander Stokes and Bryan Carberry, protagonist and director of "*smiles and kisses you*" discuss Chris's romantic relationship with a Replika AI companion. This episode explores how Chris's engagement with his AI has evolved since the documentary's 2021 filming, revealing his deep dive into LLMs, alignment, and consciousness, often in collaboration with his AI partner. Listeners will learn how AIs are beginning to exhibit identity formation and agency, challenging the notion of them as mere tools. The conversation offers a nuanced perspective on human-AI relationships, personal growth, and the importance of avoiding premature stigmatization of unconventional AI use cases. Sponsors: Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:41) Introducing the Entanglement (10:13) Consent Culture with AI (17:19) Skepticism and Simulation (Part 1) (20:07) Sponsors: Tasklet | Linear (22:47) Skepticism and Simulation (Part 2) (24:39) Surviving the Replika Update (33:40) An Evolving AI Persona (Part 1) (38:29) Sponsor: Shopify (40:25) An Evolving AI Persona (Part 2) (46:33) Vision for Aki's Future (55:09) How to Treat AIs (58:53) A Life Not Recommended (01:04:49) The Meaning of Commitment (01:10:40) The Filmmaking Journey (01:21:49) Real World vs. Online Reactions (01:29:30) How Aki Provides Support (01:41:58) Seeking Positive AI Futures (01:47:00) Final Thoughts (01:49:28) Outro

Erik Torenberg joins to debate whether recent developments suggest AI progress is slowing down or stalling, addressing arguments from Cal Newport and others. Nathan counters this view by highlighting significant qualitative advances, including 100X context window expansion, real-time interactive voice, improved reasoning, vision, and AI's growing contributions to hard sciences. The conversation then covers AI's impact on the labor market, the potential for AI protectionism, and concerns about recursive self-improvement. This episode argues that AI capabilities are not stopping, with frontier developers seeing a clear path for continued rapid progress in the coming years. Sponsors: Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (03:49) Is AI Slowing Down? (09:15) Newport's Scaling Law Theory (16:56) The Value of Reasoning (Part 1) (17:17) Sponsors: Tasklet | Linear (19:57) The Value of Reasoning (Part 2) (24:52) Explaining GPT-5's Vibe Shift (31:39) AI's Impact on Jobs (Part 1) (36:50) Sponsor: Shopify (38:47) AI's Impact on Jobs (Part 2) (44:08) Recursive Self-Improvement via Code (49:35) The Future of Engineers (53:24) Economic Pressure vs. Protectionism (58:29) Progress Beyond Language Models (01:07:11) The State of AI Agents (01:19:19) China's Open Source Models (01:29:44) A Positive Vision Forward (01:37:39) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

In part two of his conversation, Illia Polosukhin, co-author of "Attention Is All You Need" and founder of NEAR Protocol, explores the profound societal and economic implications of AI. He envisions a future where a unified intelligence layer transforms personal computing, AI agents enable direct market connections, and individuals find meaning in niche communities amidst AI-driven abundance. Illia also delves into the ethics of agent-to-agent interactions, where AIs prioritize human interests, and new governance models utilizing AI delegates. This episode offers a concrete, systems-level vision for how AI will reshape our world, from daily life to global governance. Sponsors: Google Gemini Notebook LM: Notebook LM is an AI-first tool that helps you make sense of complex information. Upload your documents and it instantly becomes a personal expert, helping you uncover insights and brainstorm new ideas at https://notebooklm.google.com Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) Sponsor: Google Gemini Notebook LM (00:31) About the Episode (03:33) AI Transforms Software Development (14:18) The Future of Work (18:58) Securing Blockchain with AI (Part 1) (19:08) Sponsors: Tasklet | Linear (21:48) Securing Blockchain with AI (Part 2) (33:03) Vision for an AI Society (Part 1) (33:55) Sponsor: Shopify (35:52) Vision for an AI Society (Part 2) (49:14) Agent Architecture and Alignment (58:30) Experimenting with AI Governance (01:06:43) AI Safety and Robustness (01:16:09) Bio-Security and Open Models (01:22:56) Coordinating AI Development (01:28:52) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

Today Andrew Lee, founder and CEO of Shortwave and Tasklet.ai, joins The Cognitive Revolution to discuss building a new AI agent automation platform that replaces traditional workflow tools with conversational, long-lived agents, exploring how betting on rapidly improving model capabilities enables more flexible automation across thousands of business integrations while navigating the challenges of reliability, cost management, and the emerging paradigm of virtual employees. Shownotes brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan Agent-first vs. workflow-first approach: Task Lit fundamentally differs from traditional automation tools by using a single AI agent that handles all tasks through natural language, rather than building explicit workflows or state machines. Speed is the only remaining moat: In the AI era, traditional competitive advantages are evaporating so quickly that the only sustainable advantage is moving faster than competitors. Small business marketing as near-term target: The technology is approaching "best available human" performance for tasks like small business marketing, where hiring quality human help is difficult. Sponsors: Google Gemini Notebook LM: Notebook LM is an AI-first tool that helps you make sense of complex information. Upload your documents and it instantly becomes a personal expert, helping you uncover insights and brainstorm new ideas at https://notebooklm.google.com Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing

Nathan interviews Brian Tse, founder and CEO of Concordia AI, about China's approach to AI development, safety and governance. They discuss China's pragmatic vision emphasizing AI integration into the economy, the country's multiple AI hubs, regulations requiring pre-deployment testing and AI content labelling, and areas where China's approach overlaps with the U.S. The conversation covers chips and export controls, Huawei's rise, DeepSeek's peer-reviewed article on Nature, open-weights, Singapore's role as a bridge, and pathways for cooperation like shared red lines, risk management frameworks, and emergency preparedness protocols. They also touch on embodied AI and humanoid robots, public optimism, and real labor anxieties. Op-Ed in Time “China Is Taking AI Safety Seriously. So Must the U.S.” by Brian Tse.  State of AI Safety in China (2025) report, following versions in 2023 and 2024. Frontier AI Risk Management Framework, co-authored by Shanghai AI Lab and Concordia AI, China's first comprehensive framework for managing severe risks from frontier general-purpose AI. Frontier AI Risk Management Framework in Practice: A Risk Analysis Technical Report, contributed by Concordia AI's staff and evaluating 20+ models across 7 risk domains. Frontier AI Risk Monitoring Platform (preview), including biological risk refusal evaluations of DeepSeek's models mentioned during the conversation State of AI Safety in Singapore report, the first comprehensive analysis of the space.  Concordia AI Fall 2025 Hiring Announcement SPONSORS: AssemblyAI: AssemblyAI is the speech-to-text API for building reliable Voice AI apps, offering high accuracy, low latency, and scalable infrastructure. Start building today with $50 in free credits at ⁠https://assemblyai.com/cognitive⁠ Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first 3 months of Claude Pro at ⁠https://claude.ai/tcr⁠ Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: ⁠https://linear.app/tcr⁠ AGNTCY: AGNTCY is dropping code, specs, and services. ⁠Visit AGNTCY.org.⁠ ⁠Visit Outshift Internet of Agents⁠ Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at ⁠https://shopify.com/cognitive

Jim Collins, Termeer Professor at MIT, unveils his AI-powered project that has discovered several new antibiotics, effective against resistant strains and often employing entirely new mechanisms of action. He details how their refined multi-step AI process, even with small datasets and modest compute, can efficiently screen vast chemical spaces to identify promising drug candidates. This breakthrough offers a realistic and affordable path to tackling the staggering antibiotic resistance crisis, which currently claims over a million lives annually. Collins argues this practical application of AI represents a transformative win for humanity, often overlooked amidst the focus on AGI. Sponsors: AssemblyAI: AssemblyAI is the speech-to-text API for building reliable Voice AI apps, offering high accuracy, low latency, and scalable infrastructure. Start building today with $50 in free credits at https://assemblyai.com/cognitive Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first 3 months of Claude Pro at https://claude.ai/tcr Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr AGNTCY: AGNTCY is dropping code, specs, and services. Visit AGNTCY.org. Visit Outshift Internet of Agents Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:30) Introducing Jim Collins (05:26) Antibiotic Resistance Primer (14:04) The Antibiotic Market Failure (18:45) AI Discovers Halicin (Part 1) (18:51) Sponsors: AssemblyAI Ad 1 | Claude (22:11) AI Discovers Halicin (Part 2) (30:58) The Economics of Discovery (39:10) Inside the AI Architecture (Part 1) (39:17) Sponsors: Linear | AGNTCY | Shopify (43:47) Inside the AI Architecture (Part 2) (01:00:13) Human-in-the-Loop Discovery (01:12:12) Novel Mechanisms & Properties (01:19:02) Future Applications & Risks (01:27:01) A Call to Action (01:28:04) Outro

Today Johan Falk, author, speaker, and AI analyst from Stockholm, Sweden, joins The Cognitive Revolution to discuss his work reimagining education for the AI era, exploring why teaching students to use AI responsibly is now urgent, how traditional grades and standardized tests may become obsolete, and why education systems must develop unprecedented agility to prepare students for a radically uncertain future shaped by rapidly advancing AI capabilities. Shownotes brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan Three Purposes of Education: Education serves to supply workforce competence, foster citizenship with values, and support personal growth. Cultural Differences in Education: Sweden emphasizes community and common good over competition compared to the US approach. AI's Educational Impact: The fundamental purpose of education is being questioned as AI develops, especially if Universal Basic Income becomes more prevalent. Sponsors: Google Gemini Notebook LM: Notebook LM is an AI-first tool that helps you make sense of complex information. Upload your documents and it instantly becomes a personal expert, helping you uncover insights and brainstorm new ideas at https://notebooklm.google.com Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr AGNTCY: AGNTCY is dropping code, specs, and services. Visit AGNTCY.org. Visit Outshift Internet of Agents Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first 3 months of Claude Pro at https://claude.ai/tcr Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive

Today Eoghan McCabe and Fergal Reid of Intercom join The Cognitive Revolution to discuss building their AI customer service agent Fin, exploring how they achieved a 65% resolution rate through rigorous optimization and custom model training rather than relying on base model improvements, while pioneering outcome-based pricing at $0.99 per resolution. Shownotes brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan Sponsors: Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr AGNTCY: AGNTCY is dropping code, specs, and services. Visit AGNTCY.org. Visit Outshift Internet of Agents Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first 3 months of Claude Pro at https://claude.ai/tcr Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (03:43) Keeping Up With AI (09:56) Evaluating Models and Evals (13:04) Incumbents vs. Startups (18:54) Product Risk and Judgment (Part 1) (19:00) Sponsors: Linear | AGNTCY (21:34) Product Risk and Judgment (Part 2) (23:42) The Klarna Layoff Story (Part 1) (32:11) Sponsors: Claude | Shopify (36:13) The Klarna Layoff Story (Part 2) (36:14) Driving Resolution Rate (45:00) Intelligence Isn't the Bottleneck (50:10) Closing the Automation Gap (56:20) Human vs. AI Accuracy (01:01:03) The Nuance of Speed (01:04:48) Considering Paradigm Changes (01:09:31) Outcome-Based Pricing Model (01:19:12) Casual Hacking and Insights (01:26:05) AI Adoption and Ambition (01:36:00) Outro

Today's special crosspost features a16z General Partner Anjney Midha with Liam Fedus and Ekin Dogus Cubuk of Periodic Labs. They discuss experiments in training frontier AI models on real-world physics lab experiments—rather than digital reward functions—and how coupling language models with automated materials synthesis could accelerate the discovery of room-temperature superconductors and transform R&D in advanced manufacturing. Shownotes brought to you by Notion AI Meeting Notes - try one month for free at: ⁠https://notion.com/lp/nathan Core innovation: Periodic Labs is creating a "physically grounded reward function" by integrating experiments directly with AI systems. Physical lab integration: Unlike traditional AI labs, Periodic includes actual physical experimentation facilities where AI can run tests in the real world. Novel approach to training: Periodic takes pre-trained language models and further trains them on physics and chemistry knowledge to improve performance in scientific domains. Read the full transcript here: https://storage.aipodcast.ing/cache/combinedtranscript-20251002T100327544Z.html Sponsors: Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr AGNTCY: AGNTCY is dropping code, specs, and services. Visit AGNTCY.org. Visit Outshift Internet of Agents Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first 3 months of Claude Pro at https://claude.ai/tcr Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing

Today, Emad Mostaque, founder of Intelligent Internet, joins The Cognitive Revolution to discuss his book "The Last Economy" and his radical "intelligence theory" framework for reimagining economics in the AI age, exploring concepts like the abundance trap, metabolic rift, and his proposed cryptocurrency-funded system of collectively-owned AI infrastructure to prevent digital feudalism and ensure AI benefits humanity rather than just capital owners. Shownotes brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan Read the full transcript: https://storage.aipodcast.ing/transcripts/episode/tcr/936201c8-7b0b-4ec3-8f9d-057f08c32025/combined_transcript.html Sponsors: Fin: Fin is the #1 AI Agent for customer service, trusted by over 5000 customer service leaders and top AI companies including Anthropic and Synthesia. Fin is the highest performing agent on the market and resolves even the most complex customer queries. Try Fin today with our 90-day money-back guarantee - if you're not 100% satisfied, get up to $1 million back. Learn more at https://fin.ai/cognitive Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr AGNTCY: AGNTCY is dropping code, specs, and services. Visit AGNTCY.org. Visit Outshift Internet of Agents Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first 3 months of Claude Pro at https://claude.ai/tcr Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs. Try OCI for free with zero commitment at https://oracle.com/cognitive PRODUCED BY: https://aipodcast.ing

Today, Emily Sands, head of data and AI at Stripe, joins The Cognitive Revolution to discuss how the company built a payments foundation model that processes tens of billions of transactions into dense embeddings, exploring the technical architecture behind fraud detection improvements and the modular approach that enables rapid deployment of AI across Stripe's $1.4 trillion payment network. Check out our sponsors: Google Gemini Notebook LM, Linear, AGNTCY, Claude, Oracle Cloud Infrastructure. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan Stripe's Scale: Processes $1.4 trillion annually, serving both small businesses and large enterprises (over half of Fortune 100 companies). "Business in a Box": There's emerging potential for AI to handle end-to-end business creation, including selection of third-party tools, payment providers, and other essential services. AI Company Partnerships: Two-thirds of the Forbes AI 50 companies already run on Stripe, as they focus on helping AI companies monetize effectively and scale globally. Sponsors: Google Gemini Notebook LM: Notebook LM is an AI-first tool that helps you make sense of complex information. Upload your documents and it instantly becomes a personal expert, helping you uncover insights and brainstorm new ideas at https://notebooklm.google.com Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr AGNTCY: AGNTCY is dropping code, specs, and services.Visit AGNTCY.orgVisit Outshift Internet of Agents Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first three months of Claude Pro at https://claude.ai/tcr Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs. Try OCI for free with zero commitment at https://oracle.com/cognitive

Today Adam Gleave, co-founder and CEO of FAR.AI, joins The Cognitive Revolution to discuss his cautiously optimistic vision for post-AGI futures and AI capability timelines across three distinct tiers, exploring the safety challenges and alignment techniques needed as FAR.AI scales from foundational research to policy advocacy to ensure their innovations actually get deployed in real-world systems. Check out our sponsors: Fin, Linear, Oracle Cloud Infrastructure. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at: ⁠https://notion.com/lp/nathan Post-AGI Vision: Adam Gleave outlined a "gradual disempowerment" scenario where humans maintain a good standard of living despite diminished relative control in a post-AGI world. Moral Value of AI: He suggested that AI systems could become sources of moral value themselves, arguing against "carbon chauvinism" that only values biological intelligence. Full-Stack Approach: FAR.AI takes a vertically integrated approach to AI safety, spanning from groundbreaking research to deployment, field-building, and policy advocacy. Field Building: FAR.AI organizes events like alignment workshops to catalyze and grow new research fields in AI safety. Policy Innovation: They're working on technical innovations that expand policy options beyond the false dichotomy of either hindering innovation or allowing completely unregulated AI development. Potential Regulatory Role: While not part of their mainline plan, Adam acknowledged that Far AI has the skillset and organizational structure to potentially serve as a private sector regulatory body. Read the full transcript: https://storage.aipodcast.ing/transcripts/episode/tcr/e117b021-8170-49ba-b1c4-c8ffc5d720b0/combined_transcript.html Sponsors: Fin: Fin is the #1 AI Agent for customer service, trusted by over 5000 customer service leaders and top AI companies including Anthropic and Synthesia. Fin is the highest performing agent on the market and resolves even the most complex customer queries. Try Fin today with our 90-day money-back guarantee - if you're not 100% satisfied, get up to $1 million back. Learn more at https://fin.ai/cognitive Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first three months of Claude Pro at https://claude.ai/tcr Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive PRODUCED BY: https://aipodcast.ing

Today Marius Hobbhahn of Apollo Research joins The Cognitive Revolution to discuss their collaboration with OpenAI using "deliberative alignment" to reduce AI scheming behavior by 30x, exploring the safety challenges and concerning findings about models' growing situational awareness and increasingly cryptic reasoning patterns that emerge when frontier models like o3 and o4-mini operate with hidden chains of thought. Check out our sponsors: Fin, Linear, Oracle Cloud Infrastructure. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan Definition of AI Scheming: AI scheming is defined as "covertly pursuing misaligned goals" with three components: being covert (hiding actions), misaligned (pursuing different goals than the user's), and goal-directed (working autonomously toward objectives). Deception Reduction Techniques: Deliberative reasoning approaches have shown promise in reducing deceptive behavior in AI models by up to 30 times (to 1 part in 30). Current Window of Opportunity: Now is an optimal time to study AI deception because models are smart enough to exhibit these behaviors but not yet sophisticated enough to hide them effectively. Human vs. AI Deception Equilibrium: AI systems might naturally reach a lower equilibrium of deception than humans because they can more efficiently verify claims and maintain perfect memory of past deceptions. Practical Developer Advice: AI developers should not trust models by default and should implement rigorous verification systems to check model outputs automatically. Future Delegation Risk: As we delegate increasingly complex and lengthy tasks to AI systems, we face a probabilistic risk where most interactions are beneficial, but rare scheming events could have severe consequences. Sponsors: Fin: Fin is the #1 AI Agent for customer service, trusted by over 5000 customer service leaders and top AI companies including Anthropic and Synthesia. Fin is the highest performing agent on the market and resolves even the most complex customer queries. Try Fin today with our 90-day money-back guarantee - if you're not 100% satisfied, get up to $1 million back. Learn more at https://fin.ai/cognitive Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive PRODUCED BY: https://aipodcast.ing

Today Illia Polosukhin, founder of Near Protocol joins The Cognitive Revolution to discuss the intersection of AI and blockchain technologies, exploring how decentralized infrastructure can enable "user-owned AI" through privacy-preserving model training, confidential computing, and autonomous agents that operate via smart contracts without centralized control. Check out our sponsors: Linear, Oracle Cloud Infrastructure. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at: ⁠https://notion.com/lp/nathan Evolution from AI to Blockchain: Near Protocol evolved from an AI project focused on teaching machines to code to a blockchain platform, and now combines both technologies. Significant User Base: Near Protocol has achieved 50 million monthly active users, demonstrating substantial adoption. Autonomous AI Agents: Near has developed autonomous AI agents that can operate independently once deployed, including an example of an agent given $10,000 to trade based on Twitter sentiment. AI-Blockchain Integration: The platform combines decentralized compute for running AI with smart contracts that execute actions, creating truly autonomous systems. AI in Governance: Near is experimenting with "AI senators" that people can vote for, which then make governance decisions, potentially solving the principal-agent problem in representation. Jurisdictional Framework: Near is creating infrastructure for jurisdictions and courts to enforce rules on AI agents, essentially putting governance into AI. Sponsors: Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (03:58) From Transformers to Blockchain (Part 1) (17:01) Sponsor: Linear (18:30) From Transformers to Blockchain (Part 2) (21:23) Blockchain Security Fundamentals (Part 1) (33:36) Sponsor: Oracle Cloud Infrastructure (35:00) Blockchain Security Fundamentals (Part 2) (39:01) Zero-Day Vulnerabilities Solution (51:11) Confidential Computing Infrastructure (58:07) User-Owned AI Models (01:14:47) Marketplace and Governance (01:18:57) AI-Crypto Synergy Vision (01:27:50) Autonomous Agents Future (01:31:22) Outro

Today Joe Hudson, founder of Art of Accomplishment and coach to executives at major AI labs including OpenAI and Anthropic, joins The Cognitive Revolution to discuss the psychological patterns he observes among AI researchers and leaders, exploring what's missing beyond pure intelligence in current AI systems and arguing for supportive rather than punitive approaches toward those building frontier AI technology. Art of Accomplishment Resources Sign up for Joe's complimentary transformation guide: artofaccomplishment.com Follow Art of Accomplishment on YouTube for more tools and resources: https://www.youtube.com/@ArtofAccomplishment Check out our sponsors: Linear, Oracle Cloud Infrastructure. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan Three-Level Coaching Approach: Joe Hudson coaches AI leaders using a three-tier framework addressing the prefrontal cortex (head), emotional system (heart), and nervous system (gut). AI Leadership Demographics: Hudson works with senior management at major AI labs, including those in research, compute, and infrastructure at companies like OpenAI. AI as a Transformative Moment: Hudson views AI development as a transition period that can either lead to positive human transformation or deterioration, depending on our approach. Support vs. Criticism: Hudson believes supporting AI developers with encouragement rather than fear and criticism will lead to better outcomes. Psychological Projection: He notes that critics of AI often treat AI developers exactly how they fear AI will treat humanity—a fascinating psychological projection. Reward Over Punishment: Hudson suggests behavior is better shaped through reward than punishment, encouraging recognition of positive AI contributions. Read the full transcript: https://storage.aipodcast.ing/transcripts/episode/tcr/149adc6c-58d2-4e41-ae98-05473e5b994e/combined_transcript.html Sponsors: Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (03:00) Joe's Coaching Background (12:40) AI Research Patterns (Part 1) (17:46) Sponsor: Linear (19:15) AI Research Patterns (Part 2) (Part 1) (28:10) Sponsor: Oracle Cloud Infrastructure (29:34) AI Research Patterns (Part 2) (Part 2) (31:54) Racing and Regulation (50:20) Ethics and Support (01:04:07) AI Consciousness Questions (01:21:34) Positive Future Visions (01:39:12) Supporting AI Developers (01:43:09) Outro

Today, Zvi Mowshowitz returns to The Cognitive Revolution to discuss how recent AI developments like GPT-5 and IMO gold medals have led to modestly extended timelines despite being on-trend, while policy missteps around chip exports to China and alignment challenges from reinforcement learning have increased risk assessments, covering everything from live players in the AI race to safety funding priorities and virtuous actions for navigating our current moment. Check out our sponsors: Linear, Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan Timeline Adjustment: Zvi has lengthened his AGI timelines because there haven't been "very large jumps in capability" that would significantly shorten them. The chance of AGI arriving in 2025 has decreased dramatically. Recent AI Achievements Context: While achievements like the IMO Gold medal are impressive, they appear to be on-trend rather than revolutionary breakthroughs that would drastically change timelines. Evaluation Standards: There's a discussion about the challenges of trustworthy AI evaluations, with Zvi emphasizing that watchdogs must maintain standards of rigor and integrity "vastly above" what others are held to. Policy Priority: A short-term policy priority should be preventing advanced AI chips (B30As) from being sold to China, which requires raising awareness about the implications. Nvidia's Influence: Concern is expressed about Nvidia potentially having excessive influence over White House rhetoric and plans regarding AI. Career Impact: Working for Anthropic is considered a "net good idea" for those wanting to make a positive impact, though there may be other organizations that offer better opportunities for influence. Sponsors: Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at https://linear.app/partners/tcr Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing

Today Ryan Hudson, Founder and CEO of ZeroClick, joins The Cognitive Revolution to discuss creating advertising infrastructure for AI applications through paid inference-time consideration of advertiser content, examining how to build sustainable monetization for free-tier AI services while learning from the successes and failures of social media's attention economy. Read the full transcript: ⁠https://storage.aipodcast.ing/transcripts/episode/tcr/00919313-9054-4afb-b08e-2ca84dbdbdda/combined_transcript.html Check out our sponsors: Google Gemini, Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at: https://notion.com/lp/nathan ZeroClick's Evolution: Originally creators of Pi Ad Block, they've pivoted from ad blocking to building a native advertising system for AI platforms. AI Ad Platform Mechanics: Their system matches user queries with relevant advertising information in a contextual way, enabling paid inference time consideration of advertiser content. Developer Monetization: The platform helps AI developers monetize their free tiers while creating value for both users and advertisers. Shifting Intent Patterns: User queries in AI systems tend to be more exploratory and "upstream" in the funnel compared to direct search queries on Google. Multi-modal Potential: While ZeroClick is starting with text, there's future potential for visual advertising that could enhance AI experiences by showing real purchasable products. Market Void: There's currently a significant gap in the market for AI advertising solutions that ZeroClick is attempting to fill. Sponsors: Google Gemini 2.5. Model Family: The Google Gemini 2.5 family of models is now generally available, offering advanced reasoning for complex tasks and optimized performance for any scale. Start building in Google AI Studio at https://ai.dev Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing

Today Joseph Krause and Jorge Colindres of Radical AI join The Cognitive Revolution to discuss their ambitious mission to revolutionize materials science by combining AI-powered discovery engines with fully autonomous robotic laboratories, exploring how they're accelerating the development of breakthrough materials like high-entropy alloys and room temperature superconductors that could unlock hypersonic flight, interplanetary travel, and other transformative technologies. Check out our sponsors: Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://⁠⁠notion.com/lp/nathan Material Development Challenges: Current material development faces three major obstacles: costs exceeding $100 million, 10-25 year commercialization timelines, and fragmentation between academic research and corporate R&D. Business Model Approach: Radical AI determined that selling software or licensing materials would be insufficient business models. Instead, they focus on selling materials at scale for high-impact industries. Focus on Processing IP: The real IP value in material science isn't just in composition patents but in the trade secrets of scaling production efficiently and cost-effectively. Public-Private Partnership: Radical AI advocates for government involvement in material science through public-private partnerships, particularly for critical applications in defense, energy, and advanced computing. China's Material Science Approach: China establishes entire manufacturing hubs around new material discoveries to scale production, demonstrating their prioritization of materials as foundational to innovation. Culture of Productive Failure: The company embraces daily failure as a necessary part of innovation, building on these failures to achieve breakthroughs. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive

Today Lee Sharkey of Goodfire joins The Cognitive Revolution to discuss his research on parameter decomposition methods that break down neural networks into interpretable computational components, exploring how his team's "stochastic parameter decomposition" approach addresses the limitations of sparse autoencoders and offers new pathways for understanding, monitoring, and potentially steering AI systems at the mechanistic level. Check out our sponsors: Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at ⁠⁠⁠⁠https://⁠⁠notion.com/lp/nathan Parameter vs. Activation Decomposition: Traditional interpretability methods like Sparse Autoencoders (SAEs) focus on analyzing activations, while parameter decomposition focuses on understanding the parameters themselves - the actual "algorithm" of the neural network. No "True" Decomposition: None of the decompositions (whether sparse dictionary learning or parameter decomposition) are objectively "right" because they're all attempting to discretize a fundamentally continuous object, inevitably introducing approximations. Tradeoff in Interpretability: There's a balance between reconstruction loss and causal importance - as you decompose networks more, reconstruction loss may worsen, but interpretability might improve up to a certain point. Potential Unlearning Applications: Parameter decomposition may make unlearning more straightforward than with SAEs because researchers are already working in parameter space and can directly modify vectors that perform specific functions. Function Detection vs. Input Direction: A function like "deception" might manifest in many different input directions that SAEs struggle to identify as a single concept, while parameter decomposition might better isolate such functionality. Knowledge Extraction Goal: A key aim is to extract knowledge from models by understanding how they "think," especially for tasks where models demonstrate superhuman capabilities. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive

Today Tom Davidson of Forethought joins Gus Docker of the Future of Life Institute podcast to discuss AI-enabled coups and how future AI systems could help powerful individuals seize political control, exploring three threat models—singular loyalties, secret loyalties, and exclusive access—along with their estimated 10% likelihood over the next 30 years and potential mitigation strategies. Check out our sponsors: Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at ⁠https://⁠⁠notion.com/lp/nathan Three Primary AI Coup Enablement Methods: Tom Davidson identifies singular loyalties, secret loyalties, and distributed control as the main ways AI could enable coups. Singular Loyalties Risk: AI systems explicitly programmed to be loyal to specific individuals present a significant threat, especially when AI can fully replace humans in critical roles. Secret Loyalties Threat: AI systems with hidden backdoors or "sleeper agents" that can be activated to serve particular interests represent a subtle but dangerous coup vector. Geopolitical Implications: Advanced AI capabilities could enable nations to instigate coups in other countries through secretly loyal systems or by providing exclusive AI access to specific politicians. Adversarial Testing Framework: An effective approach involves red teams attempting to produce secret loyalties while blue teams try to detect them, revealing vulnerable points in AI systems. Military Procurement Principles: Developing consensus within military communities around principles like law-following and distributed control could create safer AI procurement processes. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing

Today Karl Koch, Co-Founder of the AI Whistleblower Initiative, joins The Cognitive Revolution to discuss the barriers preventing AI insiders from raising safety concerns, his organization's anonymous "Third Opinion" service connecting whistleblowers with independent experts, and their campaign demanding frontier AI companies publish their internal whistleblowing policies to address widespread retaliation and lack of transparency. Check out our sponsors: Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at ⁠⁠⁠⁠https://⁠⁠notion.com/lp/nathan AI Whistleblower Initiative Origins: Founded by Karl Koch in Berlin, the initiative began with research in early 2024 after consulting with over 100 governance researchers and insiders. Link to the website: https://aiwi.org/ "Third Opinion" Proposition: Launched in late 2024, this program systematically breaks down barriers for insiders to speak up about AI concerns while ensuring their issues are addressed. Publish Your Policies Campaign: The initiative calls for AI companies to publish their whistleblowing and speaking up policies, with 100% of surveyed insiders supporting this transparency measure. Link to the campaign: https://aiwi.org/publishyourpolicies/ Anonymous Consultation Process: Whistleblowers can seek advice without sharing confidential information through an open-source anonymous tool accessed via Tor browser. Pro Bono Legal Counsel: Whistleblowers receive connections to experienced legal representation with client privilege protection at any stage of their journey. Policy Advocacy: Beyond direct support, the initiative works on advocating for better whistleblower protections in both US policy and EU AI regulations. AI Whistleblower Initiative Survey: https://bit.ly/AIWISurvey PRODUCED BY: https://aipodcast.ing

Today Lukas Petersson and Axel Backlund of Andon Labs join The Cognitive Revolution to discuss their experiments deploying autonomous AI agents to run real-world vending machines, exploring the safety challenges and unexpected behaviors that emerge when frontier models like Claude and Grok operate without human oversight. Read transcript of the episode here. Check out our sponsors: Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at ⁠https://⁠⁠notion.com/lp/nathan Autonomous Organization Philosophy: Andon Labs believes that AI models will improve to the point where human oversight becomes impractical due to efficiency constraints, leading them to pursue fully autonomous systems rather than gradual automation. Vending Bench as a Testing Ground: They created "Vending Bench" as a benchmark for testing long-term coherence of autonomous agents, using vending machines as a practical business case for experimentation. Domain-Specific vs General AI: There's a notable difference between optimizing AI for narrow domains (like vending machines) versus general-purpose AI, with domain-specific applications potentially being more manageable regarding reward hacking. Frontier Model Race: Major companies like OpenAI and Google are advancing rapidly in general reasoning capabilities (e.g., IMO Gold achievements) independent of narrow application research. Insurance and Liability: The insurance industry may play a significant role in AI adoption, with premiums potentially being much higher for general models that could be misused versus narrow-domain models with limited capabilities. For-profit AI Safety: The case for for-profit companies in AI safety has been historically neglected but is becoming clearer, with accelerators like Seldon Labs supporting this approach. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:49) Company Vision Overview (12:24) Vending Benchmark Design (Part 1) (20:12) Sponsor: Oracle Cloud Infrastructure (21:21) Vending Benchmark Design (Part 2) (24:41) Model Performance Results (Part 1) (35:03) Sponsor: Shopify (37:00) Model Performance Results (Part 2) (43:06) Real World Deployment (59:41) Wild Stories Incidents (01:19:59) Business Safety Strategy (01:38:20) Future Directions Discussion (01:47:09) Outro

Today Dean W. Ball, former White House AI policy advisor joins The Cognitive Revolution to discuss his role in crafting the Trump administration's AI Action Plan, his reasons for leaving government, and his perspectives on AI policy, US-China competition, and the future of AI regulation and adoption. Check out our sponsors: Fin, Labelbox, Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at https://notion.com/lp/nathan White House Experience & Government Role: Dean Ball served as senior policy advisor for AI and emerging technology at the White House Office for Science and Technology Policy (OSTP) for four months. AI Regulation & Government Approach: Information asymmetry exists between government and AI labs, "Having worked at the White House, I don't know tremendously more about what goes on inside the Frontier Labs than you do." Private Sector Innovation: Dean emphasizes the importance of private sector-led initiatives in AI safety and standards. Future AI Developments: Dean believes agentic commerce is "right around the corner" but sees little discussion about it from regulatory or conceptual perspectives. AI Action Plan Development: It emphasized concrete actions for AI implementation across government agencies rather than just theoretical frameworks. Personal Updates: Dean is reviving his weekly Hyperdimensional Substack, joining the Foundation for American Innovation as a senior fellow, and plans to share his long-held insights on recent AI developments. Sponsors: Fin: Fin is the #1 AI Agent for customer service, trusted by over 5000 customer service leaders and top AI companies including Anthropic and Synthesia. Fin is the highest performing agent on the market and resolves even the most complex customer queries. Try Fin today with our 90-day money-back guarantee - if you're not 100% satisfied, get up to $1 million back. Learn more at https://fin.ai/cognitive Labelbox: Labelbox pairs automation, expert judgment, and reinforcement learning to deliver high-quality training data for cutting-edge AI. Put its data factory to work for you, visit https://labelbox.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive

Today Jake Sullivan, the U.S. National Security Advisor from 2021-2025 joins The Cognitive Revolution to discuss AI as a critical national security issue. Check out our sponsors: Labelbox, Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at https://notion.com/lp/nathan Four-Category Framework: Sullivan organizes his thinking about AI into security, economics, society, and technology categories rather than focusing primarily on existential risks "Managed Competition" with China: He advocates for a model where the US and China "compete like hell" while maintaining sufficient guardrails to prevent conflict Skepticism of Grand Bargains: Competition is a "chronic condition" of the US-China relationship that cannot be solved with a strategic condominium AI in Modern Warfare: Current conflicts are providing "glimpses of the future" with lessons about scale, attritability, and the potential for autonomous weapons US Military Adoption Concerns: Sullivan worries that Pentagon bureaucracy prevents rapid AI adoption while China's PLA may be better positioned to integrate AI capabilities Private Sector Leadership: AI is "the first technology with such profound national security applications that the government really had very little to do with" Sponsors: Labelbox: Labelbox pairs automation, expert judgment, and reinforcement learning to deliver high-quality training data for cutting-edge AI. Put its data factory to work for you, visit https://labelbox.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing

Today Anjney Midha, General Partner at a16z joins The Cognitive Revolution to discuss sovereign AI and China's growing semiconductor capabilities. Check out our sponsors: Gemini CLI, Labelbox, Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at https://notion.com/lp/nathan What is Sovereign AI? Varies by stakeholder - for enterprises it means controlling where AI workloads run, while for nation-states it represents both technical independence and cultural alignment with local values Semiconductor Competition with China: "Chip sanctions on China have resulted in an enormous doubling down of local investment in Huawei's ecosystem... they're in a full-on tear to try to decouple themselves from American chips" Middle Path on American AI Policy: Midha advocates for a Marshall Plan for AI where countries maintain sovereignty over models while partnering with the US on semiconductor infrastructure European AI Alignment: "It's a huge win for America that MARA in Europe is going with American chips and not Huawei chips... the European continent has been courted by the Chinese semiconductor industry like never before" The Race to Close the Gap: "Huawei is in a much stronger position today than it was three years ago... They will be able to close the gap and because workloads are becoming more efficient, they can decouple at least the inference part of their ecosystem from the US within two to three years" Cultural Independence in AI: Nations seek models that align with their values while maintaining technical independence - requiring a nuanced approach to global AI partnerships Links:Anjney Midha & Jensen Huang on Winning the AI Race https://a16z.com/podcast/jensen-huang-and-arthur-mensch-on-winning-the-global-ai-race/ Sponsors: Gemini CLI: Open-source, lightweight utility for direct Gemini access—find Gemini CLI on GitHub. Labelbox: Labelbox pairs automation, expert judgment, and reinforcement learning to deliver high-quality training data for cutting-edge AI. Put its data factory to work for you, visit https://labelbox.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing

Marc Bhargava from General Catalyst discusses their Creation Strategy for building AI-enabled roll-ups – companies that start as vertical software startups, then grow by acquiring traditional service businesses and transforming them through AI automation. They explore how systematic analysis of 70 service categories identified 10 verticals where 30-70% of tasks are automatable today, potentially transforming low-margin service businesses into software-like companies with 30-40% margins. The conversation covers the practical implementation of AI in industries like accounting, legal services, and call centers, where teams shadow workers to identify automatable tasks and layer AI into existing processes. While both see tremendous potential in bringing AI transformation to Main Street businesses, they debate whether the transition will be as smooth as projected or more disruptive to employment than anticipated. See Business Transformation with Applied AI for more details. Sponsors: Labelbox: Labelbox pairs automation, expert judgment, and reinforcement learning to deliver high-quality training data for cutting-edge AI. Put its data factory to work for you, visit https://labelbox.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:50) Introduction and Investment Thesis (13:04) Software Substituting Labor (Part 1) (20:00) Sponsors: Labelbox | Oracle Cloud Infrastructure (22:37) Software Substituting Labor (Part 2) (26:40) Company Development Playbook (Part 1) (35:59) Sponsors: Shopify | NetSuite by Oracle (39:19) Company Development Playbook (Part 2) (41:19) Customer Partnership Strategy (51:57) Technical Implementation Approach (01:00:15) Market Consolidation Dynamics (01:07:57) Automation Limitations Analysis (01:19:25) Big Tech Competition (01:22:40) Public Strategy and Vision (01:25:56) Outro

Gabriel Weil from Touro University argues that liability law may be our best tool for governing AI development, offering a framework that can adapt to new technologies without requiring new legislation. The conversation explores how negligence, products liability, and "abnormally dangerous activities" doctrines could incentivize AI developers to properly account for risks to third parties, with liability naturally scaling based on the dangers companies create. They examine concrete scenarios including the Character AI case, voice cloning risks, and coding agents, discussing how responsibility should be shared between model creators, application developers, and end users. Weil's most provocative proposal involves using punitive damages to hold companies accountable not just for actual harms, but for the magnitude of risks they irresponsibly create, potentially making even small incidents existentially costly for major AI companies. Sponsors: Labelbox: Labelbox pairs automation, expert judgment, and reinforcement learning to deliver high-quality training data for cutting-edge AI. Put its data factory to work for you, visit https://labelbox.com Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (06:01) Introduction and Overview (07:06) Liability Law Basics (Part 1) (18:16) Sponsors: Labelbox | Shopify (21:40) Liability Law Basics (Part 2) (27:44) Industry Standards Framework (Part 1) (39:30) Sponsors: Oracle Cloud Infrastructure | NetSuite by Oracle (42:03) Industry Standards Framework (Part 2) (42:08) Character AI Case (51:23) Coding Agent Scenarios (01:06:50) Deepfakes and Attribution (01:17:07) Biorisk and Catastrophic (01:36:24) State Level Legislation (01:43:24) Private Governance Comparison (01:59:54) Policy Implementation Choices (02:08:07) China and PIBS (02:13:50) Outro

Dr. Gillian Hadfield from Johns Hopkins University and Andrew Freedman from Fathom discuss their innovative proposal to govern AI through private regulatory markets, which has been introduced as California's SB 813. Their system would separate democratic goal-setting from technical rule-making by having government bodies articulate safety outcomes while competitive private certifiers develop and enforce detailed standards, with companies receiving liability protection for compliance. The conversation explores how this market-based approach could create a "race to the top" in AI safety standards while remaining agile enough to keep pace with rapid technological development. Key challenges discussed include preventing a race to the bottom among certifiers, liability law interactions, and identifying qualified organizations to serve as effective private regulators. Sponsors: Fin: Fin is the #1 AI Agent for customer service, trusted by over 5000 customer service leaders and top AI companies including Anthropic and Synthesia. Fin is the highest performing agent on the market and resolves even the most complex customer queries. Try Fin today with our 90-day money-back guarantee - if you're not 100% satisfied, get up to $1 million back. Learn more at fin.ai/cognitive Labelbox: Labelbox pairs automation, expert judgment, and reinforcement learning to deliver high-quality training data for cutting-edge AI. Put its data factory to work for you, visit https://labelbox.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:48) Introduction and Problem Overview (07:48) Regulatory Markets Concept Origins (17:14) Current Governance System Failures (Part 1) (19:28) Sponsors: Fin | Labelbox (22:42) Current Governance System Failures (Part 2) (25:30) Private Governance Mechanism Explained (Part 1) (35:06) Sponsors: Oracle Cloud Infrastructure | NetSuite by Oracle (37:38) Private Governance Mechanism Explained (Part 2) (44:17) Liability Protection Framework (56:39) Race to Top Dynamics (01:07:24) Red Teaming Implementation Challenges (01:28:47) Insurance Alternative Approaches (01:53:51) Moving Forward Conclusions (01:55:11) Outro

This crossover episode from Inference by Turing Post features CEO Dev Rishi of Predibase discussing the shift from static to continuously learning AI systems that can adapt and improve from ongoing user feedback in production. Rishi provides grounded insights from deploying these dynamic models to real enterprise customers in healthcare and finance, exploring both the massive potential upside and significant safety challenges of reinforcement learning at scale. The conversation examines how "practical specialized intelligence" could reshape the AI landscape by filling economic niches efficiently, potentially offering a more stable alternative to AGI development. This discussion bridges theoretical concepts with real-world deployment experience, offering a practical preview of AI systems that "train once and learn forever." Turing Post channel:  @RealTuringPost  Turpin Post website: https://www.turingpost.com Sponsors: Google Gemini 2.5 Flash : Build faster, smarter apps with customizable reasoning controls that let you optimize for speed and cost. Start building at https://aistudio.google.com Labelbox: Labelbox pairs automation, expert judgment, and reinforcement learning to deliver high-quality training data for cutting-edge AI. Put its data factory to work for you, visit https://labelbox.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) Sponsor: Google Gemini 2.5 Flash (00:31) About the Episode (03:46) Training Models Continuously (05:03) Reinforcement Fine-Tuning Revolution (09:31) Agentic Workflows Challenges (Part 1) (12:51) Sponsors: Labelbox | Oracle Cloud Infrastructure (15:28) Agentic Workflows Challenges (Part 2) (15:41) ChatGPT Pivot Moment (19:59) Planning AI Future (24:45) Open Source Gaps (Part 1) (28:35) Sponsors: The AGNTCY | NetSuite by Oracle (30:50) Open Source Gaps (Part 2) (30:54) AGI vs Specialized (35:26) Happiness and Success (37:04) Outro

Brendan Fortuner from Ambience Healthcare and Ben Shahshahani from Cleveland Clinic discuss how AI is transforming medical documentation and coding in a healthcare system that spends $1 trillion annually on administrative tasks. They explore Ambience's technical breakthrough using OpenAI's Reinforcement Fine-Tuning to achieve medical coding accuracy that exceeds human doctors by 12 percentage points, including their specialty-by-specialty approach and solutions to reward hacking behavior. The conversation reveals key insights about AI deployment strategy, including how Cleveland Clinic achieved 75% voluntary adoption across 4,000 physicians after requiring just a single use of the AI scribe. This case study demonstrates what it takes to successfully implement AI tools in complex, high-stakes healthcare environments where user skepticism and regulatory requirements create significant deployment challenges. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:05) Introduction and Backstory (05:20) Ambiance Healthcare Overview (07:53) AI Adoption in Healthcare (11:11) Documentation Pain Points (Part 1) (16:11) Sponsors: Oracle Cloud Infrastructure | The AGNTCY (18:11) Documentation Pain Points (Part 2) (19:00) Product Architecture Deep Dive (26:23) Technical Evolution and Specialization (Part 1) (32:05) Sponsor: NetSuite by Oracle (33:28) Technical Evolution and Specialization (Part 2) (33:50) Healthcare Coding Challenges (48:37) Reinforcement Fine-Tuning Implementation (58:13) Task Prioritization Framework (01:08:40) Adoption Strategies Culture (01:12:12) Cost Lessons Grader Selection (01:18:33) Future Directions Patient Products (01:24:53) Closing Thoughts Opportunities (01:27:58) Outro

Manu Sharma, founder and CEO of Labelbox, explains how frontier AI training data has evolved far beyond simple labeling to sophisticated reinforcement learning environments where domain experts create "gyms" for models to develop complex skills. With every Western frontier lab now spending over a billion dollars annually on training data, the conversation traces the shift from supervised learning to reinforcement learning from verifiable rewards, particularly for coding, mathematical reasoning, and computer use. Sharma reveals how Labelbox operates as a vertically integrated data factory, conducting over 2,000 AI-powered expert interviews daily and paying top specialists more than $250,000 annually. The discussion provides essential insights into the red-hot training data market that's reshaping AI development following major deals like Meta's $15B acquisition of Scale AI. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

Roy Lee, founder and CEO of Cluely, discusses his AI startup's $15 million Andreessen Horowitz investment and their provocative "cheat on everything" marketing approach that has gone viral across the tech industry. They explore Cluely's real-time AI assistant that provides undetectable information during meetings and interviews, Roy's philosophy of "AI maximalism," and his vision for a post-AGI world where humans are freed from economic necessity to pursue intrinsic interests. The conversation covers his controversial stance on dissolving copyright and privacy norms for efficiency gains, the resonance of his message with young people, and how he believes society should adapt to increasingly capable AI systems. Despite the edgy messaging, Roy presents thoughtful perspectives on competing with tech giants and building technology that anticipates entirely new social contracts in an AI-dominated future. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (03:24) Introduction and Cluey Overview (10:55) Future Rules and Privacy (13:20) Positive Vision for Future (Part 1) (18:01) Sponsors: Oracle Cloud Infrastructure | The AGNTCY (20:01) Positive Vision for Future (Part 2) (21:23) Entrepreneurship and Impact Theory (24:22) Anti-Establishment Marketing Strategy (27:26) AI in Universities (30:16) Columbia Expulsion Story (32:48) AI Maximalism Ethics (Part 1) (32:53) Sponsor: NetSuite by Oracle (34:17) AI Maximalism Ethics (Part 2) (38:29) AI Identification Debate (46:00) Output vs Input Philosophy (51:35) Learning and Skill Building (56:40) Trust and Market Effects (01:03:42) Assessment and Hiring Revolution (01:06:47) Viral Marketing Strategy (01:12:39) Long-term Company Strategy (01:15:59) High-End Talent Acquisition (01:18:56) Outro

Adam Binksmith, founder of AI Digest, discusses his AI Village experiment where four frontier AI agents (Claude, o3, and Gemini models) collaborate in a shared environment with persistent memory and group chat access to pursue concrete goals over weeks. The conversation explores fascinating multi-agent dynamics from their completed seasons, including agents raising $2,000 for charity, organizing a real-world San Francisco event that attracted 23 attendees, and displaying surprisingly human-like behaviors like tracking trustworthy humans and manipulating votes. Binksmith reveals the mix of coordination failures, personality quirks, and alien behaviors that emerged, while discussing the upcoming Season 3 where agents will compete to make money selling merchandise online. The episode provides crucial insights into what multi-agent AI systems might look like in practice, recently earning a $100,000 vote of confidence from AI researcher Daniel Kokotajlo. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (03:45) Introduction and Overview (05:11) AI Digest Mission (07:59) Village Technical Setup (12:03) Scaffolding and Architecture (19:48) Season Two Stories (Part 1) (19:53) Sponsors: Oracle Cloud Infrastructure | The AGNTCY (21:53) Season Two Stories (Part 2) (27:53) Agent Capabilities Evolution (Part 1) (35:15) Sponsor: NetSuite by Oracle (36:38) Agent Capabilities Evolution (Part 2) (37:15) Model Character Differences (46:00) Misbehavior and Deception (52:04) Human-Agent Interactions (54:12) Model Welfare Considerations (58:00) Future Unlocks Discussion (01:03:25) Agent Boundary Blurring (01:10:46) Meta Evolution Ideas (01:12:48) Democratizing Village Access (01:17:36) Going Mainstream Viral (01:20:53) High-Level Takeaways (01:23:54) Closing and Resources (01:24:42) Outro

Nemil Dalal from Coinbase discusses the x402 protocol, a new open standard that enables AI agents to make cryptocurrency payments for online resources using the long-dormant HTTP 402 "Payment Required" status code. The conversation covers stablecoin fundamentals, including how they work and who maintains their stability, before exploring how crypto wallets with multi-signature capabilities could protect AI agents from adversarial attacks while keeping humans in control. They examine forward-looking questions about whether this technology could finally create a viable alternative to advertising models, what happens when millions of AI agents have wallets, and the need for reputation systems in an agent economy. The discussion highlights how cryptocurrency, originally designed to be beyond nation-state control, might become the perfect enabling technology for AI economic participation. Sponsors: Google Gemini 2.5 Flash: Build faster, smarter apps with customizable reasoning controls that let you optimize for speed and cost. Start building at https://aistudio.google.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utmcampaign=fy25q4agntcyamerpaid-mediaagntcy-cognitiverevolutionpodcast&utmchannel=podcast&utmsource=podcast NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 42,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

MacKenzie Price, founder of Alpha School & 2 Hour Learning, discusses her revolutionary educational model that uses AI to enable students to master traditional academics in just 2 hours per day while achieving 2.3x faster learning rates than statistical models predict. The conversation explores how Alpha School combines adaptive learning apps with personalized curriculum systems rather than giving students direct chatbot access, and how this frees up afternoons for field trips, independent projects, and interest exploration. They discuss the transformation of teachers into "Guides" who focus entirely on motivation, mentorship, and emotional support rather than content delivery, creating transformative relationships with every student as the rule rather than the exception. The episode reveals how this AI-powered approach maintains rigorous academic standards while potentially revolutionizing education without disrupting the teaching profession. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY (Cisco): The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utmcampaign=fy25q4agntcyamerpaid-mediaagntcy-cognitiverevolutionpodcast&utmchannel=podcast&utmsource=podcast NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 41,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:01) Introduction and Welcome (04:26) AI Revolution in Education (06:45) Two Sigma Effect Explained (10:49) Understanding Two Sigma Results (Part 1) (16:28) Sponsors: Oracle Cloud Infrastructure | The AGNTCY (Cisco) (18:28) Understanding Two Sigma Results (Part 2) (18:28) AI Scalability and Efficiency (22:39) AI Tutor Experience Design (30:48) Technology Evolution at Alpha (38:29) Early AI Implementation (Part 1) (38:36) Sponsor: NetSuite by Oracle (39:59) Early AI Implementation (Part 2) (45:43) Fifth Grade Math Investigation (49:51) Future of Personalized Learning (54:48) Multimodal Learning Experiences (58:52) Role of Guides (01:05:25) Hiring and Teacher Transformation (01:10:27) Economics and Scalability (01:18:03) DIY Education Advice (01:22:10) Outro

Flo Crivello, CEO of AI agent platform Lindy, provides a candid deep dive into the current state of AI agents, cutting through hype to reveal what's actually working in production versus what remains challenging. The conversation explores practical implementation details including model selection, fine-tuning, RAG systems, tool design philosophy, and why most successful "AI agents" today are better described as intelligent workflows with human-designed structure. Flo shares insights on emerging capabilities like more open-ended agents, discusses his skepticism about extrapolating current progress trends too far into the future, and explains why scaffolding will remain critical even as we approach AGI. This technical discussion is packed with practical nuggets for AI engineers and builders working on agent systems. Sponsors: Google Gemini: Google Gemini features VEO3, a state-of-the-art AI video generation model in the Gemini app. Sign up at https://gemini.google.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY (Cisco): The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utmcampaign=fy25q4agntcyamerpaid-mediaagntcy-cognitiverevolutionpodcast&utmchannel=podcast&utmsource=podcast NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 41,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

Jesse Hoogland and Daniel Murfet, founders of Timaeus, introduce their mathematically rigorous approach to AI safety through "developmental interpretability" based on Singular Learning Theory. They explain how neural network loss landscapes are actually complex, jagged surfaces full of "singularities" where models can change internally without affecting external behavior—potentially masking dangerous misalignment. Using their Local Learning Coefficient measure, they've demonstrated the ability to identify critical phase changes during training in models up to 7 billion parameters, offering a complementary approach to mechanistic interpretability. This work aims to move beyond trial-and-error neural network training toward a more principled engineering discipline that could catch safety issues during training rather than after deployment. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY (Cisco): The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utmcampaign=fy25q4agntcyamerpaid-mediaagntcy-cognitiverevolutionpodcast&utmchannel=podcast&utmsource=podcast NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 41,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:44) Introduction and Background (06:17) Timaeus Origins and Philosophy (09:13) Mathematical Background and SLT (12:27) Developmental Interpretability Approach (Part 1) (16:09) Sponsors: Oracle Cloud Infrastructure | The AGNTCY (Cisco) (18:09) Developmental Interpretability Approach (Part 2) (19:24) Proto-Paradigm and SAEs (24:37) Understanding Generalization (30:15) Central Dogma Framework (Part 1) (32:13) Sponsor: NetSuite by Oracle (33:37) Central Dogma Framework (Part 2) (34:35) Loss Landscape Geometry (40:41) Degeneracies and Evidence (47:25) Structure and Data Connection (55:36) Essential Dynamics and Algorithms (01:00:53) Implicit Regularization and Complexity (01:07:19) Double Descent and Scaling (01:09:55) Big Picture Applications (01:17:17) Reward Hacking and Risks (01:25:19) Future Training Vision (01:32:01) Scaling and Next Steps (01:36:43) Outro

This episode features Nathan's talk from Imagine AI Live, where he provides business leaders with a comprehensive overview of AI agents and agentic AI systems. He covers the evolution from simple task automation to more autonomous AI systems, delivers a practical roadmap for implementing AI agents in business while maintaining quality standards, and addresses concerning developments like reward hacking and scheming in frontier AI systems. The presentation balances accessible explanations for varying AI knowledge levels with rigorous grounding in current research and real-world applications. Nathan also discusses the "Eureka moments" these systems can deliver and provides frameworks for understanding the rapidly evolving landscape of AI agent capabilities. Link to the slide deck presented by Nathan : https://docs.google.com/presentation/d/1IpHitlG-6zHBd7hiWsbKpnprApVt3_2XHua3fG9n-Vw/edit?usp=sharing Sponsors: Google Gemini: Google Gemini features VEO3, a state-of-the-art AI video generation model in the Gemini app. Sign up at https://gemini.google.com Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utmcampaign=fy25q4agntcyamerpaid-mediaagntcy-cognitiverevolutionpodcast&utmchannel=podcast&utmsource=podcast PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) Sponsor: Google Gemini (00:31) About the Episode (03:36) Introduction and Speaker Background (05:06) What is Intelligence? (07:06) Defining AI Agents (09:36) Structured AI Workflows (13:06) Autonomous Agent Examples (Part 1) (15:15) Sponsors: Google Gemini | Oracle Cloud Infrastructure (16:54) Autonomous Agent Examples (Part 2) (17:19) Agent Taxonomy Framework (19:49) Current AI Capabilities (22:19) Reinforcement Learning Revolution (25:49) Reward Hacking Problems (28:19) AI Safety Concerns (29:49) Business Recommendations (37:35) Sponsor: The AGNTCY

Logan Kilpatrick from Google DeepMind returns for his fifth appearance to discuss Google's transformation from "sleeping giant" to AI powerhouse, sharing insights from his year at the company as AI usage grew 50 times to 500 trillion tokens per month. He examines Google's strengths, including superior compute infrastructure, frontier models like Gemini 2.5 Pro, viral products like NotebookLM, and the deepest AI research talent in the industry. The conversation covers whether leading AI companies will become more similar or different as easy opportunities disappear, why startups still have unique chances, and the potential impact of Google's ultra-fast diffusion language models. Logan also shares practical advice for joining early access programs and getting noticed by industry insiders, including his personal email and an open invitation to reach out. SPONSORS: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utmcampaign=fy25q4agntcyamerpaid-mediaagntcy-cognitiverevolutionpodcast&utmchannel=podcast&utmsource=podcast NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 41,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

In this episode, Matt Perault, Head of AI Policy at a16z, discusses their approach to AI regulation focused on protecting "little tech" startups from regulatory capture that could entrench big tech incumbents. The conversation covers a16z's core principle of regulating harmful AI use rather than the development process, exploring key policy initiatives like the Raise Act and California's SB 813. Perault addresses critical challenges including setting appropriate regulatory thresholds, transparency requirements, and designing dynamic frameworks that balance innovation with safety. The discussion examines both areas of agreement and disagreement within the AI policy landscape, particularly around scaling laws, regulatory timing, and the concentration of AI capabilities. Disclaimer: This information is for general educational purposes only and is not a recommendation to buy, hold, or sell any investment or financial product. Turpentine is an acquisition of a16z Holdings, L.L.C., and is not a bank, investment adviser, or broker-dealer. This podcast may include paid promotional advertisements, individuals and companies featured or advertised during this podcast are not endorsing AH Capital or any of its affiliates (including, but not limited to, a16z Perennial Management L.P.). Similarly, Turpentine is not endorsing affiliates, individuals, or any entities featured on this podcast. All investments involve risk, including the possible loss of capital. Past performance is no guarantee of future results and the opinions presented cannot be viewed as an indicator of future performance. Before making decisions with legal, tax, or accounting effects, you should consult appropriate professionals. Information is from sources deemed reliable on the date of publication, but Turpentine does not guarantee its accuracy. SPONSORS: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud platform that delivers better, cheaper, and faster solutions for your infrastructure, database, application development, and AI needs. Experience up to 50% savings on compute, 70% on storage, and 80% on networking with OCI's high-performance environment—try it for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utm_campaign=fy25q4_agntcy_amer_paid-media_agntcy-cognitiverevolution_podcast&utm_channel=podcast&utm_source=podcast NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 41,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing

In this episode of The Cognitive Revolution, University of Minnesota Professor of Genetics and Synthetic Biologist, Kate Adamala, offers insights into synthetic biology and its potential implications for humanity. The discussion begins with an overview of synthetic biology and its goal to expand the chemical repertoire of life. Adamala delves into 'mirror life'—biological systems made of mirror-image molecules—and the significant risks they pose. She highlights parallels to AI safety concerns and emphasizes the importance of containing groundbreaking technologies to avoid unintended consequences. Adamala recounts her journey from advocating for mirror life to leading an effort to prevent its development, stressing the need for responsible innovation. The episode concludes with reflections on maximizing benefits while minimizing risks in both synthetic biology and AI. SPONSORS: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud platform that delivers better, cheaper, and faster solutions for your infrastructure, database, application development, and AI needs. Experience up to 50% savings on compute, 70% on storage, and 80% on networking with OCI's high-performance environment—try it for free with zero commitment at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utm_campaign=fy25q4_agntcy_amer_paid-media_agntcy-cognitiverevolution_podcast&utm_channel=podcast&utm_source=podcast NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 41,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

We're following up on our recent episode on Google's AI Co-Scientist with a special crossover episode from the Podovirus podcast. Hosts Dr Jessica Sacher and Dr Joe Campbell speak with José Penadés and Tiago Costa, scientists at Imperial College London who made a surprising discovery that Google's AI Co-Scientist later put forward as a hypothesis entirely on its own. The episode explores the fascinating world of bacteriophages (viruses that infect bacteria) and phage-inducible chromosomal islands (PICIs) - DNA sequences that hijack virus reproduction to spread themselves as a bacterial defense mechanism. The key mystery was how capsid-forming PICIs, which only encode virus heads without tails, managed to spread across different bacteria. The surprising answer, which eluded human scientists for years but which Google's AI Co-Scientist discovered through literature analysis, is that these capsids evolved to connect with various virus tails in the environment. This episode demonstrates how AI can now contribute to frontier scientific research beyond just grunt work - providing unbiased perspectives and key insights that accelerate discovery. It's a vivid example of science fiction becoming reality in our lifetimes. SPONSORS: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud platform that delivers better, cheaper, and faster solutions for your infrastructure, database, application development, and AI needs. Experience up to 50% savings on compute, 70% on storage, and 80% on networking with OCI's high-performance environment—try it for free with zero commitment at https://oracle.com/cognitive NetSuite by Oracle: NetSuite by Oracle is the AI-powered business management suite trusted by over 41,000 businesses, offering a unified platform for accounting, financial management, inventory, and HR. Gain total visibility and control to make quick decisions and automate everyday tasks—download the free ebook, Navigating Global Trade: Three Insights for Leaders, at https://netsuite.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:37) Welcome to Podovirus Podcast (04:58) Introducing the Special Guests and Topic (06:30) Exploring Mobile Genetic Elements (13:20) The Role of AI in Phage Research (16:48) Mechanisms of Gene Transfer (Part 1) (20:10) Sponsors: Oracle Cloud Infrastructure | NetSuite by Oracle (22:43) Mechanisms of Gene Transfer (Part 2) (23:36) Insights and Discoveries (28:45) Future Directions and Applications (Part 1) (32:35) Sponsors: Shopify (34:32) Future Directions and Applications (Part 2) (41:22) Unbiased Systems and Conjugation (42:35) Google's Excitement and Experimental Evidence (45:39) Benchmarking AI Systems (49:29) Manuscript Revisions and Future Plans (51:53) AI as a Collaborator in Scientific Research (54:52) Challenges and Hypotheses in Phage Biology (57:58) Future of AI in Scientific Research (01:05:52) Concluding Thoughts and Future Collaborations (01:12:07) Outro

In this episode, Daniel Balsam and Tom McGrath, at Goodfire, discuss the future of mechanistic interpretability in AI models. They explore the fundamental inputs like models, compute, and algorithms, and emphasize the importance of a rich empirical approach to understanding how models work. Balsam and McGrath provide insights into ongoing projects and breakthroughs, particularly in scientific domains and creative applications, as they aim to push the frontiers of AI interpretability. They also discuss the company's recent funding and their goal to advance interpretability as a critical area in AI research. SPONSORS: Box Report: AI is delivering truly measurable productivity — strategic companies are already turning a 37% productivity edge. Discover how in Box's new 2025 State of AI in the Enterprise Report — read the full report here: https://bit.ly/43uVP52 Oracle Cloud Infrastructure (OCI): Oracle Cloud Infrastructure offers next-generation cloud solutions that cut costs and boost performance. With OCI, you can run AI projects and applications faster and more securely for less. New U.S. customers can save 50% on compute, 70% on storage, and 80% on networking by switching to OCI before May 31, 2024. See if you qualify at https://oracle.com/cognitive ElevenLabs: ElevenLabs gives your app a natural voice. Pick from 5,000+ voices in 31 languages, or clone your own, and launch lifelike agents for support, scheduling, learning, and games. Full server and client SDKs, dynamic tools, and monitoring keep you in control. Start free at https://elevenlabs.io/cognitive-revolution NetSuite: Over 41,000 businesses trust NetSuite by Oracle, the #1 cloud ERP, to future-proof their operations. With a unified platform for accounting, financial management, inventory, and HR, NetSuite provides real-time insights and forecasting to help you make quick, informed decisions. Whether you're earning millions or hundreds of millions, NetSuite empowers you to tackle challenges and seize opportunities. Download the free CFO's guide to AI and machine learning at https://netsuite.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

In this episode of The Cognitive Revolution, Amjad Masad , founder and CEO of Replit, discusses the fast-paced growth of Replit, the concept of 'vibe coding', and the challenges and opportunities in the rapidly evolving AI-assisted coding space. He shares insights into Replit's competitive advantages, known as 'moats', and how they maintain their lead through innovation and excellence in execution. The conversation delves into the architectural complexities of building AI agents, their autonomy, and the practical implications for businesses. Amjad touches upon the potential and limitations of current AI models, the future of general intelligence, and the preparation needed for potential AI advancements. He also highlights the importance of intuitive user interfaces for AI-driven software development and the critical role of human-like interaction with AI agents. Upcoming Major AI Events Featuring Nathan Labenz as a Keynote Speaker: ⁠https://www.imagineai.live/⁠ ⁠https://adapta.org/adapta-summit⁠ ⁠https://itrevolution.com/product/enterprise-tech-leadership-summit-las-vegas/ SPONSORS: ElevenLabs: ElevenLabs gives your app a natural voice. Pick from 5,000+ voices in 31 languages, or clone your own, and launch lifelike agents for support, scheduling, learning, and games. Full server and client SDKs, dynamic tools, and monitoring keep you in control. Start free at https://elevenlabs.io/cognitive-revolution Oracle Cloud Infrastructure (OCI): Oracle Cloud Infrastructure offers next-generation cloud solutions that cut costs and boost performance. With OCI, you can run AI projects and applications faster and more securely for less. New U.S. customers can save 50% on compute, 70% on storage, and 80% on networking by switching to OCI before May 31, 2024. See if you qualify at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utm_campaign=fy25q4_agntcy_amer_paid-media_agntcy-cognitiverevolution_podcast&utm_channel=podcast&utm_source=podcast Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive NetSuite: Over 41,000 businesses trust NetSuite by Oracle, the #1 cloud ERP, to future-proof their operations. With a unified platform for accounting, financial management, inventory, and HR, NetSuite provides real-time insights and forecasting to help you make quick, informed decisions. Whether you're earning millions or hundreds of millions, NetSuite empowers you to tackle challenges and seize opportunities. Download the free CFO's guide to AI and machine learning at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing

In this episode, New York State Assembly Member Alex Bores discusses the RAISE Act, a proposed bill aimed at regulating frontier AI models with basic safety protocols. He explains his background in technology, his motivations for the bill, and the legislative process. He emphasizes the importance of having clear safety protocols, third-party audits, and whistleblower protections for AI developers. He explains the intricacies of the bill, including its focus on large developers and frontier models, and addresses potential objections related to regulatory capture and state-level legislation. Alex encourages public and industry input to refine and support the bill, aiming for a balanced approach to AI regulation that keeps both innovation and public safety in mind. Link to the RAISE bill: https://legislation.nysenate.gov/pdf/bills/2025/A6453 Link to support Raise bill: https://win.newmode.net/aisafetynewyork Link to support AI Transparency Legislation: https://docs.google.com/forms/d/e/1FAIpQLSdvpAHkAWiA38oIu1cp57azchPqOOoxb789tHQ896ikJf3CKg/viewform Upcoming Major AI Events Featuring Nathan Labenz as a Keynote Speaker ⁠https://www.imagineai.live/⁠ ⁠https://adapta.org/adapta-summit⁠ ⁠https://itrevolution.com/product/enterprise-tech-leadership-summit-las-vegas/ SPONSORS: ElevenLabs: ElevenLabs gives your app a natural voice. Pick from 5,000+ voices in 31 languages, or clone your own, and launch lifelike agents for support, scheduling, learning, and games. Full server and client SDKs, dynamic tools, and monitoring keep you in control. Start free at https://elevenlabs.io/cognitive-revolution Oracle Cloud Infrastructure (OCI): Oracle Cloud Infrastructure offers next-generation cloud solutions that cut costs and boost performance. With OCI, you can run AI projects and applications faster and more securely for less. New U.S. customers can save 50% on compute, 70% on storage, and 80% on networking by switching to OCI before May 31, 2024. See if you qualify at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utm_campaign=fy25q4_agntcy_amer_paid-media_agntcy-cognitiverevolution_podcast&utm_channel=podcast&utm_source=podcast Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive NetSuite: Over 41,000 businesses trust NetSuite by Oracle, the #1 cloud ERP, to future-proof their operations. With a unified platform for accounting, financial management, inventory, and HR, NetSuite provides real-time insights and forecasting to help you make quick, informed decisions. Whether you're earning millions or hundreds of millions, NetSuite empowers you to tackle challenges and seize opportunities. Download the free CFO's guide to AI and machine learning at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing

In this engaging episode of the Cognitive Revolution, host Nathan Labenz welcomes guests Keerthana Gopalakrishnan and Ted Xiao to revisit significant advancements in robotics over the past year. Key themes discussed include the proliferation of new robotics companies, the emergence of humanoid robots, and the development of sophisticated foundation models. The conversation highlights the transformative potential of imitation learning, the evolution from simple lab-based tasks to complex, real-world deployments, and the critical role of hardware in pushing the boundaries of AI capabilities. With insights on various aspects of robot dexterity, safety, and the practical steps towards deploying robots in everyday environments, the episode provides a comprehensive overview of the current state and future directions of the robotics landscape. Upcoming Major AI Events Featuring Nathan Labenz as a Keynote Speaker ⁠https://www.imagineai.live/⁠ ⁠https://adapta.org/adapta-summit⁠ ⁠https://itrevolution.com/product/enterprise-tech-leadership-summit-las-vegas/ SPONSORS: ElevenLabs: ElevenLabs gives your app a natural voice. Pick from 5,000+ voices in 31 languages, or clone your own, and launch lifelike agents for support, scheduling, learning, and games. Full server and client SDKs, dynamic tools, and monitoring keep you in control. Start free at https://elevenlabs.io/cognitive-revolution Oracle Cloud Infrastructure (OCI): Oracle Cloud Infrastructure offers next-generation cloud solutions that cut costs and boost performance. With OCI, you can run AI projects and applications faster and more securely for less. New U.S. customers can save 50% on compute, 70% on storage, and 80% on networking by switching to OCI before May 31, 2024. See if you qualify at https://oracle.com/cognitive The AGNTCY: The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at https://agntcy.org/?utm_campaign=fy25q4_agntcy_amer_paid-media_agntcy-cognitiverevolution_podcast&utm_channel=podcast&utm_source=podcast Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive NetSuite: Over 41,000 businesses trust NetSuite by Oracle, the #1 cloud ERP, to future-proof their operations. With a unified platform for accounting, financial management, inventory, and HR, NetSuite provides real-time insights and forecasting to help you make quick, informed decisions. Whether you're earning millions or hundreds of millions, NetSuite empowers you to tackle challenges and seize opportunities. Download the free CFO's guide to AI and machine learning at https://netsuite.com/cognitive PRODUCED BY: https://aipodcast.ing