Podcasts about Lumen

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Best podcasts about Lumen

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Latest podcast episodes about Lumen

Mind & Matter
Protein Restriction & Liver Hormones: Appetite, Brain, Behavior | Chris Morrison | 251

Mind & Matter

Play Episode Listen Later Sep 12, 2025 100:18


Send us a textThe effects of protein restriction on metabolism, liver hormones, brain, and behavior.Episode Summary: Dr. Christopher Morrison talks about how animals sense and prioritize nutrients like protein, discussing defense mechanisms for essentials such as oxygen, water, sodium, and energy; the brain's role in detecting protein deprivation via signals like FGF21; trade-offs between growth, reproduction, and longevity under protein restriction; and reconciling high-protein diets for satiety and muscle maintenance with low-protein benefits for metabolic health and lifespan extension.About the guest: Christopher Morrison, PhD is a professor and researcher at the Pennington Biomedical Research Center in Baton Rouge, Louisiana, where he has worked for over 22 years focusing on nutrition, metabolism, and chronic diseases like obesity and diabetes.Discussion Points:The body prioritizes nutrients hierarchically: oxygen and water first, then sodium, energy, and protein, with weaker defenses for carbs or fats.Animals develop specific appetites for deprived nutrients, like salt or protein, often through post-ingestive learning rather than just taste.Protein restriction (e.g., 5% vs. 20% in diets) increases food intake and energy expenditure in mice to maintain protein levels, even at the cost of extra calories.FGF21, a liver hormone, signals protein deprivation to the brain (via NTS region), driving protein-seeking behavior and metabolic changes; it's essential for low-protein responses.Protein restriction extends lifespan in lab animals by suppressing growth signals like IGF-1 and mTOR, but may impair immunity or wound healing in real-world conditions.High protein aids satiety, weight loss, and muscle building, but overconsumption may shorten lifespan; optimal intake depends on age, activity, and goals (e.g., not for pregnant or elderly).No one-size-fits-all for protein: mild restriction may benefit middle-aged sedentary people for health, while athletes need more; balance avoids excesses.Related content:M&M 106: Diet, Macronutrients, Micronutrients, Taste, Whole vs. Processed Food, Obesity & Weight Loss, Comparative Biology of Feeding Behavior | Stephen Simpson & David Raubenheimer*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Telecom Reseller
Lumen Positions as AI Infrastructure Partner at ScanSource Partner First, Podcast

Telecom Reseller

Play Episode Listen Later Sep 12, 2025 4:08


“We are now branding ourselves as the trusted infrastructure supporter of AI,” says Scott Eaton, Sr. Director, Partner Management at Lumen, in a conversation with Doug Green, Publisher of Technology Reseller News, during ScanSource Partner First. Eaton explained that Lumen, built on the combined legacies of CenturyLink, Level 3, Savvis, and Global Crossing, has transitioned from its telco roots into a technology company focused on powering AI with bandwidth and infrastructure services. Through solutions like wave services, DIA services, data centers, and rapid routes, Lumen provides the backbone for enterprises facing high-intensity data demands. At Partner First, the company highlighted its long-standing partnership with Intelisys, now part of ScanSource, where it has operated for over 20 years in an agency model of recurring commissions. Eaton emphasized that Lumen enables resellers to expand beyond equipment sales and deliver complete customer solutions—moving from “mailbox money” to strategic recurring revenue streams. To simplify adoption, Lumen and ScanSource provide partners with API-driven quoting and ordering tools, training, and field engineering support. This ensures that partners can more easily engage in infrastructure sales, which Eaton described as essential for AI-era growth: “From an AI perspective, it's all about the data… and the high bandwidth requirements to support it.” Eaton noted that partners at the show are eager to learn how to get started, educate themselves, and go deeper with customers. He encouraged resellers to leverage both Lumen's resources and ScanSource's support teams to accelerate success. For more information, visit lumen.com.

Taste Life Nutrition Podcast
Your Precision Wellness Blueprint: The Science of YOU

Taste Life Nutrition Podcast

Play Episode Listen Later Sep 10, 2025 57:06


In this episode, we broke down why one-size-fits-all diets don't work—and why your health depends on uncovering your unique blueprint. We explored the power of body typing, functional lab testing, and cutting-edge tech tools like Lumen, CGMs, and InBody scans to reveal the science of YOU. Key takeaways from today's conversation:

BauMentor - Der Hausbau-Podcast
#181 - Die perfekte Beleuchtung für jeden Raum

BauMentor - Der Hausbau-Podcast

Play Episode Listen Later Sep 9, 2025 10:12


Licht schafft Atmosphäre, beeinflusst unsere Stimmung und macht aus vier Wänden ein echtes Zuhause. In dieser Episode zeigen wir euch, wie ihr für jeden Raum die passende Beleuchtung findet – von gemütlichem Wohnzimmerlicht über funktionale Küchenlampen bis hin zu entspannendem Schlafzimmerambiente. Ihr erfahrt, wie ihr direkte und indirekte Beleuchtung clever kombiniert, warum LEDs nicht nur energieeffizient, sondern auch vielseitig sind, und welche Rolle Faktoren wie Lumen und Kelvin bei der Lichtplanung spielen. Außerdem verraten wir euch praktische Tipps, wie ihr mit dem richtigen Lichtkonzept Räume größer, wärmer oder freundlicher wirken lassen könnt. Lasst euch von uns zeigen, wie ihr mit der richtigen Beleuchtung eine echte Wohlfühlatmosphäre schafft – und warum Licht mehr ist als nur Helligkeit. Viel Spaß beim Anhören, euer BauMentor-Team!

The Hawk's Nest Podcast
Seahawks Fall at Home to Shorthanded 49ers 17-13

The Hawk's Nest Podcast

Play Episode Listen Later Sep 8, 2025 14:30


The divisional rival 49ers rolled into Lumen far from full strength and yet more than earned the victory they walked away with after a hard-fought game. There are plenty of excuses, but the bottom line appears Seattle is still not on San Francisco's level. Link to my YouTube Channel. Live on Wed and Sunday, 5PM PST...https://www.youtube.com/@TheHawksNest12thman?sub_confirmation=1 Use promo code NEST on Sleeper and get 100% match up to $100! https://Sleeper.com/promo/NEST. Terms and conditions apply. #Sleeper Link to my Patreon....https://www.patreon.com/thehawksnest Twitter...@SeahawksNester Twitch...@TheSeahawksNest

Mind & Matter
Cognition, Form, Regeneration & Metaphysics: Does Biology Arise From Math? | Michael Levin | 250

Mind & Matter

Play Episode Listen Later Sep 7, 2025 68:34


Send us a textSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

OHNE AKTIEN WIRD SCHWER - Tägliche Börsen-News
“Mattel zu billig?” - Broadcom, Sanofi, Covestro, mit PE-Fonds in Carglass investieren?

OHNE AKTIEN WIRD SCHWER - Tägliche Börsen-News

Play Episode Listen Later Sep 5, 2025 14:00


Hier gibt's mehr Infos zum Private-Equity-Angebot von Scalable Capital. Der Kalender zum Podcast? Jetzt kaufen. Sweeney & American Eagle provozieren erfolgreich. Lumen will mit Palantir KI-Firma sein. Goldman Sachs x T. Rowe Price & Citigroup x BlackRock. Sanofi leidet. Porsche & Sartorius fliegen aus DAX. Lululemon & Broadcom mit Zahlen. Covestro hat EU-Stress. Das Spielzeug von Mattel (WKN: 851704) hat jeder. Die Aktie fast niemand. Ein Fehler? „Carglass repariert, Carglass tauscht aus.“ In den ikonischen Jingle kann man an der Börse leider nicht investieren. Aber in den Carglass-Miteigentümer: Den BlackRock Private Equity Fund (WKN: A410GZ). Diesen Podcast vom 05.09.2025, 3:00 Uhr stellt dir die Podstars GmbH (Noah Leidinger) zur Verfügung.

Mind & Matter
Fructose, Microglia, Anxiety & Brain Development | Justin Perry | 249

Mind & Matter

Play Episode Listen Later Sep 3, 2025 99:43


Send us a textCellular clean up by immune cells and how early-life fructose exposure leads to neurodevelopmental problems.Episode Summary: Dr. Justin Perry talks about the body's constant cellular turnover—about 3 million cells die per second in adults (double in children and women)—handled by phagocytes like macrophages that engulf and digest debris to prevent diseases like lupus. They explore phagocytosis steps, macrophage adaptations in tissues like the brain (microglia), and how high fructose intake impairs microglial function in developing mice, leading to uncleared brain cells and anxiety-like behaviors, with implications for human neurodevelopmental disorders amid rising fructose consumption.About the guest: Justin Perry, PhD is an immunologist and clinical psychologist who leads a lab at Memorial Sloan Kettering Cancer Center focusing on how the body clears dead cells and debris to maintain homeostasis.Discussion Points:The body turns over 1-2% of its 30 trillion cells daily, mostly blood cells, but neurons in kids and endometrium in women turnover at ~2x this ratePhagocytosis involves "find me," "eat me," and digestion signals; failures can cause autoimmunity.Microglia are brain macrophages that uptake fructose via GLUT5 transporter.Early high fructose exposure (comparable to one soda daily) impairs the pruning of synapses and dead neurons.In mice, prenatal or postnatal fructose causes phagocytosis deficits in the prefrontal cortex, leading to heightened fear responses and poor fear extinction, mimicking anxiety disorders.Fructose correlates with rising neurodevelopmental issues like autism and anxiety; it's passed via breast milk, and liquid forms (e.g., sodas) overwhelm metabolic shields more than solid fruits.Macrophages may hold keys to diseases from atherosclerosis to cancer; deleting GLUT5 in microglia reverses fructose's effects, hinting at evolutionary roles in aging or low-oxygen states.Related content:M&M 215: Cancer Metabolism: Sugar, Fructose, Lipids & Fasting | Gary PattiArticle | Dietary Fructose & Metabolic Health: An Evolutionary PerspectiveReference Paper:Study | Early life high fructose impairs microglial phagocytosis and neurodevelopment*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

ACR Journals On Air

In this episode of ACR Journals on Air, host Dr. Vicki Shanmugam speaks with Dr. Alain Sanchez-Rodriguez about a new study from the Lupus Midwest Network (LUMEN), published in Arthritis Care & Research. They explore how patients with systemic lupus erythematosus (SLE) experience delays and disparities in care, the types of physicians involved in diagnosis, and what the data reveals about access to specialized treatment. Dr. Sanchez-Rodriguez also shares his research journey and insights on improving equity in rheumatology. 

#BeMaingrounder Radio Podcast
Carlos Perez B2B K-Style @ Aquasella 2025 (17/08/2025)

#BeMaingrounder Radio Podcast

Play Episode Listen Later Sep 1, 2025 81:52


Videoset disponible: https://youtu.be/BsF4v8ciopY Follow K-Style: https://www.instagram.com/kstyledavid Follow Carlos Pérez: https://www.instagram.com/carlosperezdj

Iglesia Noticia
08:30H | 31 AGO 2025 | Iglesia Noticia

Iglesia Noticia

Play Episode Listen Later Aug 31, 2025 29:00


El programa "Iglesia Noticia" se centra en el persistente llamado del Papa León XIV al fin del terror, la destrucción y la muerte en Tierra Santa, abogando por un alto el fuego permanente y la ayuda humanitaria. El pontífice promueve la reconciliación y rechaza la violencia. Otros temas destacados incluyen la apertura de la causa de canonización de Avelino Aguilera y 50 mártires, la celebración del Día Mundial de Oración por el Cuidado de la Creación y la publicación de un libro con los primeros mensajes del Papa. Se aborda la preocupación del Papa por la falta de sacerdotes y el creciente papel de los misioneros laicos, ejemplificado por el viaje del obispo de Bilbao a Vietnam. En España, continúan las obras de restauración en la Mezquita-Catedral de Córdoba y se investigan ataques vandálicos en el santuario de San Miguel de Aralar. Se anuncia la elección de Fray Javier Carballo como nuevo Prior de los Dominicos de Hispania y la creación de Lumen, un asistente virtual con ...

Mind & Matter
Autism, Acetaminophen (Tylenol) & Oxidative Stress | William Parker | 248

Mind & Matter

Play Episode Listen Later Aug 29, 2025 101:49


Send us a textThe potential link between acetaminophen (Tylenol) and autism, with a surprise phone call from RFK partway through.Episode Summary: Dr. William Parker talks about autism spectrum disorder (ASD), its rising prevalence since the 1980s, and the controversial hypothesis that acetaminophen exposure in susceptible infants and children triggers most cases via oxidative stress. They discuss ASD's clinical definition; historical misconceptions like the "refrigerator mother" theory; genetic susceptibilities; acetaminophen's metabolism, which produces toxic byproducts in underdeveloped livers, leading to brain effects.About the guest: William Parker, PhD spent nearly 30 years as a professor at Duke University researching underlying causes of chronic conditions, including discovering the immune function of the human appendix and pioneering studies on immune systems in wild animals.Discussion Points:Autism is a spectrum disorder with core symptoms like social deficits, repetitive behaviors, and aversion to new stimuli.Parker argues overwhelming evidence points to acetaminophen as the primary trigger in susceptible individuals, causing oxidative stress via toxic metabolite NAPQI.Acetaminophen, marketed as Tylenol or paracetamol, was not tested for neurodevelopmental effects in neonatal animals until 2014, despite widespread use since 1886; it's metabolized differently in babies, whose livers lack mature detox pathways.Susceptibility factors include low glutathione (an antioxidant), poor sulfation/glucuronidation metabolism, folate receptor autoantibodies, and events like immune reactions that prompt acetaminophen use during oxidative stress.Regressive autism, where children lose milestones after seeming normal, often follows acetaminophen given for fevers or illnesses, explaining parental vaccine suspicions (as shots coincide with drug use).Adult acetaminophen is generally safe but causes liver toxicity in overdoses or with alcohol; antidote is NAC to boost glutathione.Parker has suggested to policymakers that we should avoid acetaminophen during pregnancy, birth, and early childhood (under age 3-5); parents should plan ahead for fevers/pain without it, but seek medical help for unusual symptoms.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

The David Pakman Show
8/27/25: GOP loses seat badly, Trump has soldiers picking up trash

The David Pakman Show

Play Episode Listen Later Aug 27, 2025 64:06


-- On the Show: -- Democrat Catelin Drey defeats Republican Christopher Prosch in an Iowa Senate special election flipping a Trump district and ending the GOP supermajority -- Donald Trump deploys more than 2,200 National Guard troops from multiple states to collect trash in Washington DC as part of a beautification mission -- The White House pushes back as questions mount over Donald Trump's health after visible bruises, swelling, and cognitive slip-ups -- Trump makes false claims about crime, autism, prescription drugs, and restaurants while Robert F Kennedy Jr rants about radioactive shrimp during a chaotic cabinet meeting -- Cabinet officials and allies, including Tulsi Gabbard, Kristi Noem, Kelly Loeffler, and others, lavish praise on Donald Trump in an extraordinary display of flattery -- Support among young men who backed Trump in 2024 collapses as economic struggles, immigration raids, and broken promises sour his appeal -- California Governor Gavin Newsom publicly raises concerns about Trump's mental fitness -- Trump mocks Gavin Newsom's hand movements while Newsom fires back online -- Trump posts a series of late night Truth Social rants boasting about fundraising, crime, and attacking Seth Meyers -- Charlie Kirk tells Taylor Swift to reject feminism and submit to her fiancé, Travis Kelce, in a bizarre rant about their engagement -- On the Bonus Show: Trump signs an executive order against flag burning, Trump wants to change the Defense Department's name to the Department of War, US threatens to withhold funding from states over truck driver English proficiency rules, and much more...

Mind & Matter
Cholesterol: Immune Benefits, Heart Health, Statins & Research Malpractice | Uffe Ravnskov | 247

Mind & Matter

Play Episode Listen Later Aug 25, 2025 55:09


Send us a textWide release date: August 25, 2025Episode Summary: Dr. Uffe Ravnskov talks about his decades-long career challenging the idea that high cholesterol causes heart disease, discussing LDL's protective role in the immune system by binding to bacteria, the harms and biases in statin research influenced by pharmaceutical companies, evidence that high cholesterol benefits the elderly and reduces infection/cancer risks, and how mental stress or infections elevate cholesterol as a response rather than a cause.About the guest: Uffe Ravnskov, MD, PhD is a physician and independent researcher who earned his MD from the University of Copenhagen in 1961 and a PhD in nephrology. He has worked in various clinics in Sweden since the 1960s, focusing his research on challenging the cholesterol hypothesis in heart disease. Now 91, he has published over 200 papers, authored books like "The Cholesterol Myths.”Discussion Points:LDL cholesterol helps the immune system by sticking to bacteria, clumping them for removal; low LDL increases infection risk.Animal studies show injecting LDL protects against lethal infections, while historical data links severe infections to worse atherosclerosis.Elderly people with high cholesterol live longer; low cholesterol raises mortality risk more than high levels.Familial hypercholesterolemia (FH) doesn't cause early death via cholesterol alone—co-inherited coagulation factors are the issue, and FH patients often have lower infection rates.Statins lower LDL but increase infection risk, cause muscle weakness/brain issues (often blamed on aging), and show no clear benefit in unbiased meta-analyses.Research biases include cherry-picking studies, exaggerating benefits via relative (not absolute) risk, and pharma funding suppressing critical views.Mental stress can raise cholesterol by 10-50% in 30 minutes, often misread as a heart disease cause rather than an effect.Saturated fat and high cholesterol aren't proven harmful; Ancel Keys' claims ignored contradictory evidence.Stopping statins often reverses side effects quickly, improving quality of life.Related episode:M&M 244: Seed Oils & Heart Disease: Oxidized LDL, Cholesterol, Fat & Cardiology | Tucker GoodrichReference Paper:LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Soul Mates!
S3E5 Oatmeal For Yaoi Doctors

Soul Mates!

Play Episode Listen Later Aug 25, 2025 162:54


In this episode, an episode about eating semisolid foods while experiencing a medical crisis, we zoom in on our featured Operator and Food, the styling stormswept seafaring fish doctor Lumen, who's delicate constitution needs to be warmly nurtured, and...Jello...who's scary...we ask the question...what flavor is she...scary flavor...? Then, bring out the band with Jade Noodles, Wiš'adel, and Phoenix Tail Prawn, asking a very important question of you, dear listener: Do you think the hardworking men who care for our communites, who care for our loved ones, our children and our qilin, deserve love, support, and nutrients of their own? We do. That's why Soul Mates! is a proud supporter of the #OatmealForYaoiDoctors movement, and we want you to be to. Share it on your social media, or with your friends and family. Don't let this important cause go unnoticed. Join the movement. Get it trending. #OatmealForYaoiDoctors Follow along:  https://arknights.wiki.gg/wiki/Lumen,  https://food-fantasy.fandom.com/wiki/Jello,  https://food-fantasy.fandom.com/wiki/Jade_Noodles,  https://arknights.wiki.gg/wiki/Wi%C5%A1%27adel,  https://food-fantasy.fandom.com/wiki/Phoenix_Tail_Prawn Support the show:  https://ko-fi.com/ivyfoxart Follow the show on Tumblr:  https://soul-mates-podcast.tumblr.com/ Follow the show on YouTube:  https://www.youtube.com/@Soul-Mates-Podcast Listen to Together We'll Shine: An Utena Rewatch Podcast:  https://bunnygirlbrainwave.substack.com/archive Art by Ryegarden:  https://www.instagram.com/ryegarden Music by Sueños Electrónicos:  https://suenoselectronicos.bandcamp.com/ Follow and support ash:  https://ko-fi.com/asherlark

The Cooler Guild
Deep dished at Lumen - Ep. 43

The Cooler Guild

Play Episode Listen Later Aug 20, 2025 51:49


It was all good until it wasn't. After being up 3-0 against Chicago the Reign decided to pull a Kingdome and implode by conceding 3 goals in the second half, resulting in a disappointing draw at home. With defensive struggles on full display we discuss this disappointing draw but also talk about the recent phenomenon of the Jordyn Huitema effect. Additionally we do Reign trivia, cover the other results around the league, and preview the Reign's next match.SPONSORSSounder at Heart - Our network host and biggest supporter, Sounder at Heart covers the Seattle Sounders, Seattle Reign, and MUCH MORE! Subscribe to Sounder at Heart and get 1 FREE month.The Doctor's Office - Located in Capitol Hill, The Doctor's Office is an intimate global spirits tasting room with classic cocktails and an emphasis on personalized service. TDO Seattle is proud to be The Cooler Guild's first sponsor.-----Follow us on social media:TCG IGYouTubeBluesky:TCGCoopVanShow produced by CoopTheme song by Alex JuarezShow artwork by CoopThe Cooler Guild Est. 2024

The David Pakman Show
8/19/25: Zelenskyy-Trump meeting chaos as veggie prices surge 40 percent

The David Pakman Show

Play Episode Listen Later Aug 19, 2025 63:35


-- On the Show: -- Donald Trump reverses his ceasefire stance after meeting Vladimir Putin and pressures Volodymyr Zelenskyy to accept land concessions without a ceasefire -- Trump fails to see Finnish President Alexander Stubb sitting directly in front of him and asks where he is during a public event -- Trump blames Barack Obama for losing Crimea and defends Vladimir Putin while dismissing Ukraine's NATO aspirations -- Trump praises Vladimir Putin during a red carpet meeting and blames Ukraine for getting invaded while downplaying Russia's aggression -- Wholesale vegetable prices surge nearly 40 percent in July raising fears of sharp increases in grocery costs for consumers -- Washington DC restaurant reservations plunge more than 25 percent after Donald Trump federalizes the police and militarizes the city -- Gavin Newsom rises in Democratic primary polls for 2028 after his redistricting efforts -- Fox News personalities criticize Gavin Newsom for mocking Trump online exposing hypocrisy about Trump's own years of ridicule -- On the Bonus Show: Texas Democrats monitored by law enforcement after returning to state, Trump vows to end mail-in voting, Ohio's Sherrod Brown launches bid for US Senate, and much more... ⚠️ Ground News: Get 40% OFF their unlimited access Vantage plan at https://ground.news/pakman

Mind & Matter
Appendix, Gut Worms, Allergies & Autoimmunity | William Parker | 246

Mind & Matter

Play Episode Listen Later Aug 19, 2025 79:56


Send us a textThe appendix's hidden role and how "good" parasites like helminths shape immune health.Episode Summary: Dr. William Parker discusses gut anatomy, the appendix's role in harboring beneficial bacterial biofilms and immune tissue, and how modern hygiene depletes helminths (intestinal worms), causing immune overreactions like allergies, autoimmunity, and psychiatric conditions. He explores helminth self-therapy for treating relapsing MS, depression, and allergies; challenges in clinical trials due to patent issues; and why COVID-19 was milder in low-income, helminth-rich regions.About the guest: William Parker, PhD conducted research at Duke University for over 27 years on immunology, appendicitis, and the hygiene hypothesis. After retiring from Duke, he serves as a visiting scholar at the University of North Carolina at Chapel Hill, leading efforts on biome reconstitution via helminths.Discussion Points:Appendix is not vestigial; it concentrates immune tissue and biofilms to cultivate good gut bacteria, preventing pathogens via mucus and IgA antibodies.Hygiene hypothesis: Soap, toilets, and clean water reduce helminths/protozoa, leading to untrained, hyperactive immunity and rising allergies/autoimmunity since the 1800s.Helminths (worms) stimulate immune "exercise," training immunity; biohackers use hookworms (cheap, skin-entry), porcine whipworms, or rat tapeworms orally for relief from allergies, MS flares, depression/anxiety.Effects are temporary; need ongoing exposure (e.g., replenish every 6 months); immigrants from helminth-rich areas develop Western diseases within a few years.COVID-19: Hyper-immunity caused severe reactions in hygienic West, but helminth presence in low-income Africa/Asia prevented cytokine storms, leading to empty clinics.Therapy barriers: Non-patentable organisms require $100M+ trials; push for open-source, government-funded biome restoration over crude immunosuppressants.Related episode:M&M 144: Inflammation, Innate Immunity, Allergies & Allergens, Immune System Evolution, Fasting & Metabolism | Clare Bryant*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

El ojo crítico
El ojo crítico - Redescubrir a Anne Frank a través del dibujo de María Hesse

El ojo crítico

Play Episode Listen Later Aug 19, 2025 55:35


Casi todos conocemos de forma general la historia de Anne Frank, pero pocos la recuerdan en detalle. Esa niña nacida en el seno de una familia judía alemana llevó una vida normal hasta que el ascenso del nacionalsocialismo obligó a su familia a emigrar a Ámsterdam. Allí, junto a sus padres, su hermana y cuatro refugiados más, se ocultó en una buhardilla que se convertiría en símbolo universal de la memoria del Holocausto. El final de la historia es conocido, pero lo esencial está en el camino, en el testimonio escrito que la convirtió en una voz inmortal. Ese trayecto vuelve a la actualidad gracias a la ilustradora María Hesse, que ha reinterpretado 'El diario de Anne Frank' en una nueva edición publicada por Lumen. En la segunda parte del programa, Miguel Ángel Delgado nos acompaña en el paseo semanal por los ensayos y libros de divulgación científica, una sección que conecta el pensamiento con la actualidad de la investigación.La danza de raíz tradicional es protagonista en Les Preses, en Girona, donde comienza el festival Esdansa. Con una veintena de espectáculos de compañías nacionales e internacionales, la cita reivindica la fuerza de lo popular y lo ancestral en diálogo con la creación contemporánea. La cobertura corre a cargo de Marta Orquín.El programa se cierra en el Museo Arqueológico Nacional. El MAN, cuya colección permanente recibió un impulso tras su reforma hace una década, mantiene un ritmo constante de renovación gracias a sus exposiciones temporales. Tras haber repasado la muestra 'Alas para la guerra', dedicada a los cascos celtíberos, hoy nos centramos en otras dos propuestas muy distintas que explica Ángela Núñez, subrayando la diversidad de miradas que ofrece el museo.Escuchar audio

The No Proscenium Podcast
Gillian Leitten, CEO of The Lumen Prize

The No Proscenium Podcast

Play Episode Listen Later Aug 15, 2025 65:02


This week we're joined by Gillian Leitten, CEO of The Lumen Prize because today is that day that the 99 finalists for the Prize are announced (check the Show Notes) and Leitten is here to talk with us about the prize which celebrates artists forging new systems of meaning through technology's evolving creative frontier.We give a special focus on the Hybrid and Experiential categories, the later of which is the evolution of last year's Interactive/Immersive category and for the second year in a row features the most finalists of any category, 16 in total.SHOW NOTESThe Lumen PrizeThe 2025 Lumen Prize Finalists Hosted on Acast. See acast.com/privacy for more information.

The Psychologists Are In with Maggie Lawson and Timothy Omundson
Maggie Talks To Asher Grodman About His Life with Zazie on Unconditional

The Psychologists Are In with Maggie Lawson and Timothy Omundson

Play Episode Listen Later Aug 14, 2025 75:14


This week we are airing another episode of Unconditional featuring the hilarious Ghosts star, Asher Grodman, to talk about his deep bond with his dog, Zazie. From her playful energy to her unwavering companionship, Asher shares how Zazie has been a grounding force in his life, especially during challenging times.   Sponsors: Go to  Lumen.me/pineapple for 15% off your purchase.Cornbread Hemp - Save 30% on your first order by going to ⁠cornbreadhemp.com/pineapple⁠ and use the code “pineapple” at checkout.Quince Cookware: ⁠quince.com/maggie⁠ for free shipping and 365 day returnsQuince Apparel: ⁠quince.com/pineapple⁠ for free shipping and 365 day returns Learn more about your ad choices. Visit megaphone.fm/adchoices

Dave 'Softy' Mahler and Dick Fain
Softy & Dick 8-13 Hour 3: Larry Stone, Hawks' Starters, Lumen Age

Dave 'Softy' Mahler and Dick Fain

Play Episode Listen Later Aug 14, 2025 37:08


In the third hour, Dave Softy Mahler and Dick Fain chat with Larry Stone about the red hot Mariners, MVP race, Josh Naylor, and the fallout of the Portland Trailblazers sale, then discuss the Seahawks preseason plans for Friday and if Lumen Field is too old.See omnystudio.com/listener for privacy information.

Mind & Matter
Cannabinoid System: Metabolism, Evolution & Energy Storage | Giovanni Marsicano | 245

Mind & Matter

Play Episode Listen Later Aug 13, 2025 104:55


Send us a textWhat is the core evolved function of the endocannabinoid system?Episode Summary: Dr. Giovanni Marsicano is a neuroscientist based in Bordeaux, France, where he leads a research group at INSERM focusing on the endocannabinoid system.About the guest: Giovanni Marsicano, PhD discusses the endocannabinoid system, starting with its core components like CB1 receptors and lipid-based molecules derived from omega-6 fatty acids; its cellular signaling, evolutionary role in energy storage for uncertain futures (exostasis vs. homeostasis); effects across tissues; motivation, appetite, pain relief, and anxiety regulation; biphasic effects of cannabinoids.Discussion Points:The endocannabinoid system acts as an "exostatic" regulator, promoting energy accumulation for future needs by enhancing food palatability, nutrient absorption, and fat storage, unlike "endostatic" systems that address immediate hunger.CB1 receptors appear in vertebrates with adipose tissue, suggesting an evolutionary link to storing fat for survival in unstable environments.Endocannabinoids are lipids from omega-6 fats; high intake boosts their levels, potentially fueling obesity by creating a self-perpetuating cycle of overeating.Activation of CB1 can have biphasic effects due to receptors on different cell types like excitatory vs. inhibitory neurons.Pregnenolone, a steroid precursor, acts as a natural CB1 inhibitor to prevent excessive activation, blocking harmful effects like psychosis from high THC doses.The system influences motivation beyond food, including sex and even human activities like sports or storytelling, by rewarding actions for potential future benefits.In the brain, CB1 on mitochondria and astrocytes modulates energy use, olfaction, and social stress transmission, with implications for disorders like Alzheimer's.Reference Paper:CB1 Receptor as the Cornerstone of ExostasisRelated episode:M&M 123: EndocanSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

The David Pakman Show
8/12/25: Inflation highest in 6 months, layoffs highest in 5 years

The David Pakman Show

Play Episode Listen Later Aug 12, 2025 62:52


-- On the Show: -- Inflation rose sharply in July under Trump's economy, driven by tariffs causing prices to increase above the Fed's ideal range -- Trump's firing of the Bureau of Labor Statistics head raises questions about the credibility and political influence on inflation and jobs data -- Layoffs in the US surged to the highest level since the COVID pandemic, fueled by federal job cuts, tariffs, AI automation, and private sector downsizing -- Trump's takeover of DC police and deployment of National Guard troops sparked protests and potential resistance from the Guard -- Trump's strange remarks about sidewalk scrubbing during a speech leave his staff bewildered -- Trump's FBI Director Kash Patel publicly contradicted MAGA narratives by reporting record low murder rates, enraging Trump -- Donald Trump confused Alaska with Russia during a speech, exposing incoherence and hypocrisy in right-wing media responses -- Trump's press secretary Karoline Leavitt had a visible meltdown on camera when asked a simple question about the Epstein scandal -- Marjorie Taylor Greene publicly attacks other MAGA figures, exposing internal conflict and power struggles within the movement -- Jeanine Pirro struggled when confronted with real crime data showing declines, undermining the MAGA narrative -- Defense Secretary Pete Hegseth dodged questions about the fate of homeless people after Trump's plans to clear homeless encampments -- On the Bonus Show: Pete Hegseth retweets Christian nationalist pastor, Project 2025 guy picked for BLS leader, MTG accused of sketchy stock trading, and much more...

4 Feinde
LICHT, LUMEN, LUX UND LUMINANZ (Séparée Folge 32)

4 Feinde

Play Episode Listen Later Aug 11, 2025 65:02


Premium-Folge vom 11.10.2024. Licht an Hirn aus! 3 Feinde lassen die Schalter knallen im Séparée! Tickets für unsere Solo-Shows: https://linktr.ee/4feinde

Mind & Matter
Seed Oils & Heart Disease: Oxidized LDL, Cholesterol, Fat & Cardiology | Tucker Goodrich | 244

Mind & Matter

Play Episode Listen Later Aug 7, 2025 99:25


Send us a textOverview and alternative interpretation to the mainstream view on how dietary fat and cholesterol relate to cardiovascular disease.Episode Summary: Tucker Goodrich is an engineer by training who has become a prominent independent researcher and blogger on nutrition and metabolic health, focusing on the harms of seed oils and polyunsaturated fats.About the guest: Nick Jikomes and Tucker Goodrich explore atherosclerosis and heart disease, critiquing the standard model that blames high LDL cholesterol while highlighting how oxidized LDL—driven by dietary linoleic acid from seed oils—plays a key role in plaque formation and inflammation; they discuss historical shifts in heart disease rates, genetic factors like familial hypercholesterolemia, the limitations of animal studies, and why reducing seed oil intake could prevent issues more effectively than just lowering cholesterol.Discussion Points:Atherosclerosis involves plaque buildup in arteries, often leading to heart attacks, but plaques contain oxidized fats and cholesterol, not just native cholesterol.Dietary cholesterol has little impact on blood levels or heart disease in humans, unlike in rabbits used in many studies.High LDL may not be inherently bad; oxidized LDL from polyunsaturated fatty acids (PUFAs) like linoleic acid causes macrophages to overeat and form harmful foam cells.Familial hypercholesterolemia patients only show higher heart disease rates in modern, industrial diets high in seed oils, not historically.Populations like the Kitavans and Tsimané have high apoB but no heart disease on traditional diets low in industrial foods.Fried foods are oxidized seed oils, explaining why they're unhealthy despite omega-6 fats being labeled "heart-healthy."Omega-3 fats can displace omega-6 in cells, reducing oxidation risk.Reference Papers:Witztum & Steinberg (1991)Boren et al. (2022)Related episode:Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

The David Pakman Show
8/4/25: Trump fires the messenger as economy gets shaky

The David Pakman Show

Play Episode Listen Later Aug 4, 2025 82:23


-- On the Show: -- Donald Trump lashes out with angry social media posts as economic indicators show signs of decline -- Donald Trump fired Bureau of Labor Statistics head Erika McEntarfer after a devastating jobs report exposed major economic weakness -- Republican Senators like Cynthia Lummis and Thom Tillis finally criticize Donald Trump after he Bureau of Labor Statistics head Erika McEntarfer for political reasons -- Donald Trump's DOJ moved Ghislaine Maxwell to minimum-security after a secret meeting, raising serious questions about favors and Epstein connections -- Donald Trump was loudly booed by thousands at WWE SummerSlam during a video appearance, showing a shocking drop in support -- Donald Trump made disturbing comments about press secretary Karoline Leavitt's lips on TV, raising concerns about sexism and power abuse -- Press secretary Karoline Leavitt demanded Trump receive the Nobel Peace Prize, pushing the cult of personality narrative to absurd heights -- Donald Trump discusses the Epstein files, pardons, drug prices, and lashes out about loyalty and job numbers -- MAGA spokespeople struggle to defend Trump's false economic claims amid historic job report revisions -- Trump lashes out on Truth Social accusing Biden appointees of rigging jobs data and demands firings while denying economic reality -- Trump claims he fired a government official over disputed jobs numbers and insists on having trusted personnel amid growing economic uncertainty -- A leaked DHS memo reveals plans to militarize immigration enforcement domestically, alarming experts about authoritarian risks -- Newsmax spins July jobs report disaster as “good news” ignoring massive downward revisions and recession fears -- On the Bonus Show: Trump attacks Charlamagne tha God, Tesla's brand loyalty plummets, Nancy Mace announces run for Governor of South Carolina, and much more... ⚠️ Ground News: Get 40% OFF their unlimited access Vantage plan at https://ground.news/pakman

Mind & Matter
Evolution & Variation in Human Diet, Energy Expenditure & Metabolism | Herman Pontzer | 234

Mind & Matter

Play Episode Listen Later Aug 1, 2025 109:42


Send us a textHuman metabolism, primate evolution, and modern health challenges with evolutionary anthropologist Herman Pontzer.Episode Summary: Anthropologist Dr. Herman Pontzer discusses human evolution and metabolism, comparing humans to primates like chimps and gorillas to explain our higher energy use, bigger brains, and longer lives despite trade-offs in reproduction and activity; they discuss dietary shifts from plant-based to hunting-gathering, metabolic adaptations, and modern issues like obesity, where exercise aids health but diet drives weight loss, emphasizing ultra-processed foods' role in overeating and the promise of new drugs like GLP-1 agonists.About the guest: Herman Pontzer, PhD is a professor of evolutionary anthropology and global health at Duke University. He is the author of books like "Burn" and "Adaptable," which explore how bodies adapt to diets, activity, and environments.Discussion Points:Humans burn 20% more daily energy than other primates (controlling for body size), enabling big brains, more babies, and longer lives, but requiring efficient food strategies like hunting and gathering.Unlike apes, humans evolved smaller guts, higher body fat (15-30% vs. apes'

Never Stop The Madness - Black Metal Radio

676 - Recorded live on July 29, 2025 Longer show, including a tribute to Ozzy! Ambience for the night: Grimoire de Occulte - Ajna:Transmissions https://grimoiredeocculte.bandcamp.com/album/ajna-transmissions **Playlist** 1) Stangarigel - Turoni a chriapy obchádzajú snehom 2) Tumulus - Wodans Jagd 3) Ymesh - SATAN 4) Night - Dregs 5) Helheim - Hamr **talk** 6) Drunemeton - Mother Europe (Ancient Rites cover) 7) Aürc - Adversarial Nature 8) Thursbane - Oathbound 9) Ayyur - The High Throne 10) Mars Ultor - Shining Steel **talk** 11) Ancient Torment - Spectre at the Crossroads 12) Wolftomb - Cold Mists of Wildlands 13) Pöllömaagi - Lumen leijonat (Maailman veri labyrintissä) 14) Balmog - Mashalam **talk** *Ozzy Tribute* *Ambience: Piano Dreamers - Piano Dreamers Cover Ozzy Osbourne* 15) Black Sabbath - Evil Woman, Don't Play Your Games with Me (Crow cover) 16) Sabbat - S.A.T.O. (Ozzy cover) 17) Módugr - Bark At The Moon (Ozzy cover) 18) Myrholt - Tegn fra Universet (Black Sabbath cover) 19) Rondellus - Planetarum vagatio (Black Sabbath cover) 20) Black Sabbath - Scary Dreams (live) **talk** 21) Ozzy Osbourne - The Ultimate Sin 22) Ozzy Osbourne - You Can't Kill Rock and Roll Live every Tuesday at 9pm ET on NSTMRadio.com

Ciena Network Insights
Episode 88: Mastering MOFN—Lumen and Ciena experts share their insights

Ciena Network Insights

Play Episode Listen Later Aug 1, 2025 23:20


Have you been hearing the term Managed Optical Fiber Networks (MOFN) more and more lately? In this episode, Lumen Technologies' Alison Greenwood, Vice President of Hyperscalers, and Martin Reilly, Director of International MOFN at Ciena, join Kent Jordan of Ciena Product Marketing for an in-depth discussion about all things MOFN. You'll learn about MOFN's benefits, business models, and emerging trends, and hear about Lumen's experiences, successes, and lessons learned.

The Ben Shapiro Show
Ep. 2249 - WINNING: Trump's EPA WRECKS The Radical Green Agenda

The Ben Shapiro Show

Play Episode Listen Later Jul 30, 2025 74:07


The Trump EPA radically revises regulations over greenhouse gas emissions, and we're joined by Energy Secretary Chris Wright to discuss the energy revolution; Cory Booker gets performative on the Senate floor; and The New York Times admits a horrifying screw-up in its Gaza coverage. Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2249 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Watch Journey to the UFC: Joe Pyfer now—streaming exclusively on DailyWire+. My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiro Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: Perplexity - Perplexity is an AI-powered answer engine that searches the internet to deliver fast, unbiased, high-quality answers, with sources and in-line citations. Ask Perplexity anything here: https://pplx.ai/benshapiro PureTalk - Switch to PureTalk and start saving today! Visit https://PureTalk.com/SHAPIRO Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen. CovePure - Go to https://covepure.com/shapiro to get $200 off. One Nation America - Learn more at https://OneNationAmerica.org - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53  Follow on Instagram: https://bit.ly/3QtuibJ  Follow on Facebook: https://bit.ly/3TTirqd  Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy Learn more about your ad choices. Visit megaphone.fm/adchoices

The Ben Shapiro Show
Ep. 2249 - WINNING: Trump's EPA WRECKS The Radical Green Agenda

The Ben Shapiro Show

Play Episode Listen Later Jul 30, 2025 69:08


The Trump EPA radically revises regulations over greenhouse gas emissions, and we're joined by Energy Secretary Chris Wright to discuss the energy revolution; Cory Booker gets performative on the Senate floor; and The New York Times admits a horrifying screw-up in its Gaza coverage. Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2249 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Watch Journey to the UFC: Joe Pyfer now—streaming exclusively on DailyWire+. My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiro Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: Perplexity - Go to https://helixsleep.com/klavan to get an exclusive discount. PureTalk - Switch to PureTalk and start saving today! Visit https://PureTalk.com/SHAPIRO Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen. CovePure - Go to https://covepure.com/shapiro to get $200 off. One Nation America - Learn more at https://OneNationAmerica.org - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53 Follow on Instagram: https://bit.ly/3QtuibJ Follow on Facebook: https://bit.ly/3TTirqd Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy

Mind & Matter
Sunlight: Cosmology, Energy Metabolism & the Physics of Life | Robert Fosbury | 242

Mind & Matter

Play Episode Listen Later Jul 27, 2025 133:07


Send us a textThe deep connection between sunlight and life, from the scale of the cosmos to the quantum.Episode Summary: Astrophysicist Dr. Robert Fosbury discusses the sun's characteristics as a star, its analogies to living systems via entropy and complexity, and Erwin Schrödinger's insights on life as order-maintaining entities; he explores how near-infrared (NIR) light from the sun penetrates bodies to enhance mitochondrial function and metabolism, critiques modern artificial lighting's health impacts like mitochondrial dysfunction leading to diseases, and advocates returning to natural light environments for better wellness, drawing connections from cosmology to everyday architecture and lifestyle.About the guest: Robert Fosbury, PhD is a is a retired astrophysicist. He spent his career at the European Space Agency, working on Hubble and JWST projects, and now pursues interdisciplinary research linking stellar phenomena to biological processes like light's impact on vision and metabolism.Discussion Points:Stars like the sun maintain low-entropy states by exporting entropy as light, mirroring how life ingests low-entropy food to sustain order and homeostasis.The universe's complexity peaks midway in entropy increase, with stars producing elements that enable biological complexity, evolving toward cognition.Near-infrared light, peaking in solar output at ~1.6 microns due to atmospheric physics, catalyzes mitochondrial ATP production by facilitating electron transport, not via photosynthesis but photo-metabolism.Modern LEDs and windows block near-infrared, contributing to mitochondrial dysfunction, obesity, diabetes, and aging; historical thermal lights like incandescents provided beneficial infrared.Outdoor environments, especially under trees, flood bodies with reflected near-infrared for health, while blue skies act as cold sinks boosting thermodynamic efficiency.Eyes are mitochondria-rich, vulnerable to poor light; therapies using near-infrared slow macular degeneration by improving energy production.Ultra-processed foods are "high-entropy" with no structural order, akin to waste, reducing nutritional value for maintaining bodily order.Practical fixes: Use low-voltage incandescents indoors, prioritize outdoor time, design buildings with infrared-transmitting glass, and light people, not spaces, for energy savings and Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

The Ben Shapiro Show
Ep. 2245 - Tulsi's BOMBSHELL: Team Obama Doctored Intel To Push Russiagate

The Ben Shapiro Show

Play Episode Listen Later Jul 24, 2025 85:31


Director of National Intelligence Tulsi Gabbard declassifies a House Intelligence Committee report showing the Obama team doctored intel to conclude that Russia wanted Trump in 2016; journalist Michael Tracey joins us to discuss what's actually in the Epstein files; and President Trump brings Columbia University to heel.Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHEEp.2245- - -Facts Don't Care About Your Feelings- - -DailyWire+:Right now you can gift Daily Wire plus for 40% off with code JULY at DailyWire.com/gift (https://www.dailywire.com/gift).My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiroGet your Ben Shapiro merch here: https://bit.ly/3TAu2cw- - -Today's Sponsors:ExpressVPN - Go to https://expressvpn.com/ben and find out how you can get 4 months of ExpressVPN free!Cookunity - Go to https://www.cookunity.com/benfree for Free Premium Meals for Life. Thanks to CookUnity for supporting the show!Policygenius - Head to https://policygenius.com/SHAPIRO to get your free life insurance quotes and see how much you could save.Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen.One Nation America - Learn more at https://OneNationAmerica.org- - -Socials:Follow on Twitter: https://bit.ly/3cXUn53Follow on Instagram: https://bit.ly/3QtuibJFollow on Facebook: https://bit.ly/3TTirqdSubscribe on YouTube: https://bit.ly/3RPyBiB- - -Privacy Policy: https://www.dailywire.com/privacy

The David Pakman Show
7/24/25: Trump in Epstein files, Tulsi tries to save him, MAGA revolts

The David Pakman Show

Play Episode Listen Later Jul 24, 2025 70:37


-- On the Show: -- Jimmy Gomez, Democratic Congressman representing California's 34th Congressional District, joins David to discuss ICE raids, deportations, and Trump sending troops to Los Angeles -- Trump was personally briefed by Pam Bondi that his name appears in the Epstein files, which were then sealed by his DOJ -- Trump's defense lawyer was sent to meet Ghislaine Maxwell as Congress prepares the Epstein subpoenas -- Tulsi Gabbard leads Trump's latest disinformation push, targeting Barack Obama with unproven coup allegations -- Trump melts down on Truth Social as legal and political crises mount -- Tulsi Gabbard's comments contradict MAGA beliefs about Epstein's CIA ties, causing chaos in the base -- Karoline Leavitt fumbles questions on Epstein, AI, and Obama prosecutions in a disastrous press conference -- Trump's tech speech devolves into nonsense about AI, GDP, and “woke” staff -- Trump calls for Obama's arrest, ignoring that presidential immunity he fought for would protect Obama too -- On the Bonus Show: Trump floats no tax on home sales, EPA says greenhouse gases are fine, Macrons sue Candance Owens for defamation, and much more...

Mind & Matter
Synapse Energetics & Fat Metabolism in the Brain | Timothy Ryan | 241

Mind & Matter

Play Episode Listen Later Jul 23, 2025 85:59


Send us a textHow brain synapses work and fuel themselves with fat.Episode Summary: Dr. Timothy Ryan talks about the high energy costs of synapses, the role of mitochondria and glycolysis, and challenge the long-held view that the brain relies solely on glucose by discussing new evidence that neurons burn fats from lipid droplets for fuel, especially during activity. The talk touches on metabolic flexibility, links to epilepsy treatments like ketogenic diets, neurodegenerative diseases, and future research on brain energy sources.About the guest: Timothy Ryan, PhD is a professor of biochemistry at Cornell University. His research focuses on the molecular mechanisms of synaptic transmission, particularly vesicle recycling and the bioenergetics that power neural communication. Discussion Points:Synapses are tiny structures with ~100 vesicles per site (on average), converting electrical signals to chemical ones.Brain tissue is energy-hungry due to trillions of synapses (in humans), relying on local mitochondria (present in only ~half of synapses) and glycolysis.Vesicles use proton pumps and transporters to concentrate neurotransmitters, requiring ATP to maintain gradients.Neurons are metabolically fragile; cutting fuel supply quickly impairs synapses.Dogma held brains don't burn fats, but new work shows neurons form lipid droplets (fat stores) that are invisible because constantly used for energy via beta-oxidation.Silencing neurons builds lipid droplets like resting muscle; activity speeds their breakdown, indicating demand-driven fat use.Inhibiting neuron-specific fat-processing enzymes accumulates droplets and induces torpor (hibernation-like state) in animals, signaling metabolic stress.Ketogenic diets aid epilepsy by shifting to ketones; fats may explain this, with potential ties to aging and neurodegeneration like Alzheimer's.Brain may be a "hybrid" fuel user (glucose + fats), with open questions on fat sources and roles in cognition or disease protection.Related episode:M&M 158: Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

She Coaches Coaches
The Unknown Bucket List: Transform Your Coaching by Embracing Life's Unexpected Turns with J. Lumen Ep: 277

She Coaches Coaches

Play Episode Listen Later Jul 23, 2025 19:11


In this powerful episode, Candy interviews J Lumen, a transformation coach who turned a life-threatening experience into a mission to help others break free from silent dissatisfaction. J introduces her innovative "Unknown Bucket List" approach—a perspective shift that helps people recognize their overlooked achievements and use them as evidence of their capacity to create change. This conversation offers profound insights for coaches at any stage, revealing how embracing vulnerability and acknowledging your unique story can transform both your coaching practice and your clients' lives. Featured on This Show:Click here to find out how to work with meClick here to access valuable free resources for coaches Instagram: https://www.instagram.com/candymotzek/LinkedIn: https://www.linkedin.com/in/candy-motzek/J. LumenJ. Lumen has dedicated the last decade to helping others break free from living silently in dissatisfaction through her speaking and coaching. Her unique journey surviving an unexpected attempt on her life fuels her passion to help audiences realize their overlooked power to redefine their life experience. She's inspired countless individuals to embrace their Unknown Bucket List, promoting an innovative approach to life's unpredictability and how to start living the life they want. Website: https://theunknownbucketlist.com/

Morning Wire
Russiagate Conspiracy Revealed & Dignity Act Debate | 7.21.25

Morning Wire

Play Episode Listen Later Jul 21, 2025 15:36


Declassified Obama-era emails yield new revelations about the Trump-Russia probe, President Trump sues the WSJ over an alleged connection to Epstein, and a bipartisan bill in Congress would shield millions of illegal immigrants from deportation. Get the facts first with Morning Wire. - - - Today's Sponsors: Lumen - Go to https://lumen.me/WIRE to get 10% off your Lumen. Shopify - Go to https://Shopify.com/morningwire to sign up for your $1 per month trial period and upgrade your selling today. - - - Privacy Policy: https://www.dailywire.com/privacy

The David Pakman Show
7/16/25: Trump health goes viral over swollen ankles, top MAGA warns about 2026

The David Pakman Show

Play Episode Listen Later Jul 16, 2025 74:51


-- On the Show: -- Jake Tapper, CNN Anchor and Chief Washington correspondent, joins David to discuss his book “Original Sin: President Biden's Decline, Its Cover-Up, and His Disastrous Choice to Run Again” -- Steve Bannon warns Republicans could lose 40 seats if Trump doesn't release the Epstein files, as MAGA allies rage over his DOJ closing the case -- Trump is seen with swollen ankles and possible IV bruises, fueling speculation about hidden health issues - - Trump dodges Epstein questions and downplays the scandal, raising suspicion with his dismissive and evasive responses -- A newly uncovered DOJ letter confirms the Trump administration had possession of Epstein-related documents -- Trump accuses Senator Adam Schiff of mortgage fraud and demands his arrest in a Truth Social tirade -- Trump stumbles through interviews, contradicts himself, lashes out, and gets defensive over Epstein, Putin, and Bongino amid mounting backlash -- Bill O'Reilly forgets key Epstein timeline facts on air, mirroring a broader right-wing narrative that falsely pins blame on Biden instead of Trump -- On the Bonus Show: Republicans now backing Ukraine, Josh Hawley tries to restore Medicaid funds he voted to cut, Mike Waltz blames Signalgate on Biden, and much more...

Morning Wire
Trump's Ukraine U-Turn & Biden's Autopen Admissions | 7.15.25

Morning Wire

Play Episode Listen Later Jul 15, 2025 16:01


Trump shifts his policy on aid to Ukraine while threatening Putin, the midterms may spell trouble for the GOP, and Biden breaks his silence over the investigations into his autopen use. Get the facts first with Morning Wire. - - - Today's Sponsors: Balance of Nature - Go to https://balanceofnature.com and use promo code WIRE for 35% off your first order as a preferred customer PLUS get a free bottle of Fiber and Spice. Lumen - Go to https://lumen.me/WIRE to get 10% off your Lumen. - - - Privacy Policy: https://www.dailywire.com/privacy

What Was That Like
222: Scott was locked up in a foreign jail

What Was That Like

Play Episode Listen Later Jul 11, 2025 107:19


As human beings, we are often very protective of our own sense of personal justice – and injustice.   When I was a child, I had a teacher who – to me – seemed very unfair. If one of the kids in the class did something like write a bad word on the chalkboard, she would ask the entire class who did it. She really did her best to find the culprit, and carry out punishment.   But sometimes she just couldn't figure it out. No one would admit it, and there wasn't enough evidence to pin it on any specific student.   So her solution was – the whole class loses recess for the whole day. Definitely not fair! It always bugged me when that happened – I was being punished even though I hadn't done anything wrong.   My guest today, Scott, was also a victim of injustice, but on a much larger scale. He was charged with a crime that he didn't commit, and was held in a foreign jail for far too long. This is one of those stories where you just can't predict what's coming next.   And if you're an American, it might just make you think twice before traveling outside the US.     If you'd like to contact Scott:  thescottmcmahonstory@outlook.com   Full show notes and pictures for this episode are here: https://WhatWasThatLike.com/222   Graphics for this episode by Bob Bretz. Transcription was done by James Lai.   Want to discuss this episode and other things with thousands of other WWTL listeners? Join our podcast Facebook group at WhatWasThatLike.com/facebook (many of the podcast guests are there as well)   Get every episode ad-free, AND get all the Raw Audio exclusive episodes to binge, by joining the other listeners at What Was That Like PLUS.   Try What Was That Like PLUS free: iPhone: at the top of the What Was That Like podcast feed, click on “Try free” Android: on your phone, go to WhatWasThatLike.com/PLUS and click to try it free on any app   Sponsor deals: Head to http://Lumen.me/WWTL for 20% off your purchase.   Sign up today at https://www.butcherbox.com/whatwas and use code whatwas to get chicken breast, salmon or ground beef FREE in every order for a year, plus $20 off your first order.   Cut your wireless bill to 15 bucks a month at mintmobile.com/WHAT   Go to Quince.com/whatwas for free shipping on your order and 365-day returns!   Get 15% off OneSkin with the code [WHATWAS] at https://www.oneskin.co/ #oneskinpod Learn more about your ad choices. Visit megaphone.fm/adchoices

The Ben Shapiro Show
Ep. 2235 - The SMOKING GUN In The Biden Cover-Up?

The Ben Shapiro Show

Play Episode Listen Later Jul 10, 2025 71:28


Joe Biden's doctor takes the Fifth when asked whether Biden was healthy or not; President Trump's team undercuts him on Ukraine's defense; and the administration targets California for failing to defend girls in sports. Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2235 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Join millions of people who still believe in truth, courage, and common sense at https://DailyWirePlus.com. My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiro Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: ExpressVPN - Go to https://expressvpn.com/ben and find out how you can get 4 months of ExpressVPN free! SimpliSafe - Visit https://SIMPLISAFE.com/SHAPIRO to claim 50% off a new system with a professional monitoring plan and get your first month free. Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen. IFCJ - To learn more about IFCJ's lifesaving work, visit https://benforthefellowship.org Birch Gold - Text BEN to 989898 for your free information kit.  - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53 Follow on Instagram: https://bit.ly/3QtuibJ Follow on Facebook: https://bit.ly/3TTirqd Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy

The Psychologists Are In with Maggie Lawson and Timothy Omundson
Tim & Maggie Talk About The 19th Anniversary Of The Psych Debut & Their New TV Shows

The Psychologists Are In with Maggie Lawson and Timothy Omundson

Play Episode Listen Later Jul 10, 2025 49:10


This week, Tim and Maggie look back on the 19th anniversary of Psych and how their lives have changed since then. Tim talks about his now-iconic beard and Maggie shares what it's like filming Boston Blue in Toronto—plus a look at where the podcast is filming live in the coming weeks! This episode is sponsored by Lumen - Go to ⁠lumen.me/pineapple⁠ for 15% off your Lumen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Morning Wire
Trump Buries Epstein & Farm Labor Finds Future | 7.9.25

Morning Wire

Play Episode Listen Later Jul 9, 2025 15:47


President Trump fields questions on tariffs, Ukraine, and Epstein during his sixth Cabinet meeting, fallout continues from the Central Texas floods, and the Administration rejects amnesty but hints at flexibility for some illegal immigrant workers. Get the facts first with Morning Wire. - - - Today's Sponsors: Zocdoc - Find and instantly book a top-rated doctor today. Visit https://Zocdoc.com/WIRE #sponsored Lumen - Go to https://lumen.me/WIRE to get 10% off your Lumen. - - - Privacy Policy: https://www.dailywire.com/privacy

The David Pakman Show
7/8/25: Trump played like a fiddle as troops descend on Los Angeles park

The David Pakman Show

Play Episode Listen Later Jul 8, 2025 85:51


-- On the Show: -- David hosts a Substack Live with Brian Tyler Cohen -- Trump deploys militarized federal forces to MacArthur Park in Los Angeles in a chilling test run of authoritarian power projection -- Karoline Leavitt embarrassingly backpedals on the Epstein list, exposing a key MAGA lie and deepening Trump's credibility crisis -- Trump's team can't explain what happened to the long-promised Epstein client list, casting doubt on years of MAGA conspiracy claims -- Trump's press secretary spirals on live TV, failing to defend collapsing trade deals, flood response failures, and a phantom Epstein list -- Trump delays his tariff threat again, proving once more that his “tough” trade stance is all bluff and political cowardice -- Trump floods world leaders with unhinged tariff letters, creating global confusion and economic anxiety -- Trump rambles incoherently at a White House dinner, praising dictators, flip-flopping on trade, and exposing chaos behind his Ukraine and tariff policies -- Benjamin Netanyahu flatters Trump with a fake Nobel Prize nomination and Trump falls for it completely, clueless he's being manipulated -- On the Bonus Show: Ted Cruz vacations again during Texas natural disaster, inhumane conditions reported at Alligator Alcatraz, IRS says churches can endorse candidates, and much more... ⚠️ Ground News: Get 40% OFF their unlimited access Vantage plan at https://ground.news/pakman

The Psychologists Are In with Maggie Lawson and Timothy Omundson
Maggie Talks To Oliver Stark About His Love For Animals on Unconditional

The Psychologists Are In with Maggie Lawson and Timothy Omundson

Play Episode Listen Later Jul 3, 2025 91:20


Since we're on hiatus this week, we wanted to bring you a cute episode from Unconditional! Actor Oliver Stark (from one of our favorite shows, 9-1-1) sits down with Maggie and talks about all of the love and sometimes heartbreak that can go into having a pet and how much Oliver's life has changed from experiences rescuing animals. Subscribe to the Unconditional at apple.co/unconditional and follow on Instagram @unconditionalpod This episode is sponsored by Lumen - Go to lumen.me/pineapple for 15% off your Lumen. Learn more about your ad choices. Visit megaphone.fm/adchoices

The Exorcist Files
Fr. Martins Answers Questions On The End Times, Demonic Obsession and Spiritual Warfare

The Exorcist Files

Play Episode Listen Later Jul 2, 2025 49:30


Fr. Matins answers a slate of spiritual warfare questions includingFreemasonry Deliverance PrayersThe End TimesDemonic ObsessionDemonic LanguageMichael's Dispute over the Body of Moses and more!Thank you to our sponsorsRemi- Try Remi risk-free at shopremi.com/EXFILES and use CODE EXFILES to get up to 50% off your nightguard at checkout!Lumen- Handheld metabolic insights. Get your Lumen today at lumen.me/exfilesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Morning Wire
Trump's NATO Win & Senate Debates OBBB | 6.26.25

Morning Wire

Play Episode Listen Later Jun 26, 2025 15:35


Trump secures increased funding from NATO members, Senate Republicans consider the One Big Beautiful Bill, and a therapy student blows the whistle on mandatory training in smut. Get the facts first with Morning Wire. - - - Today's Sponsors: Lumen - Go to https://lumen.me/WIRE to get 10% off your Lumen. Lean - Get 20% off when you enter MORNINGWIRE20 at https://TakeLean.com - - - Privacy Policy: https://www.dailywire.com/privacy

The Ben Shapiro Show
Ep. 2222 - Trump's FINAL ULTIMATUM: Two Weeks To Stop The Attack!

The Ben Shapiro Show

Play Episode Listen Later Jun 20, 2025 65:54


President Trump lays out his final ultimatum: he'll make a call on attacking Iran's nuclear facilities within two weeks; we analyze all the various possibilities; and why are people falling in love with their AI chatbots? Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2222 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Join millions of people who still believe in truth, courage, and common sense at https://dailywireplus.com My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiro Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: Perplexity - Perplexity is an AI-powered answer engine that searches the internet to deliver fast, unbiased, high-quality answers, with sources and in-line citations. Ask Perplexity anything here: https://pplx.ai/benshapiro ExpressVPN - Go to https://expressvpn.com/ben and find out how you can get 4 months of ExpressVPN free! Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen. SimpliSafe - Visit https://SIMPLISAFE.com/SHAPIRO to claim 50% off a new system with a professional monitoring plan and get your first month free. Shopify - Sign up for your one-dollar-per-month trial and start selling today at https://shopify.com/shapiro - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53 Follow on Instagram: https://bit.ly/3QtuibJ Follow on Facebook: https://bit.ly/3TTirqd Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy

The Ben Shapiro Show
Ep. 2211 - A Big Announcement! Plus Trump's NEW Travel Ban!

The Ben Shapiro Show

Play Episode Listen Later Jun 5, 2025 89:24


I have a major announcement; President Trump announces a fresh travel ban aimed at radical Muslim countries; Elise Stefanik stops by; and Tucker Carlson attacks Mark Levin. Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2211 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Save 40% on DailyWire+ Gift Memberships for Father's Day with code DAD40 at https://dailywire.com/gift My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiro Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: Perplexity is an AI-powered answer engine that searches the internet to deliver fast, unbiased, high-quality answers, with sources and in-line citations. Ask Perplexity anything here: https://pplx.ai/benshapiro Birch Gold - Text BEN to 989898 for your free information kit. Shopify - Sign up for your one-dollar-per-month trial and start selling today at https://shopify.com/shapiro Boll & Branch - Get 15% off, plus free shipping on your first set of sheets at https://BollAndBranch.com/ben LifeLock - Join now and save up to 40% your first year. Call 1 (800) LifeLock and use promo code BEN or go to https://LifeLock.com/BEN for 40% off. Terms apply. Helix Sleep - Go to https://helixsleep.com/ben for an exclusive offer. Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen. - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53 Follow on Instagram: https://bit.ly/3QtuibJ Follow on Facebook: https://bit.ly/3TTirqd Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy