Podcasts about Lumen

It's election day in New York City – so will New Yorkers commit political suicide? Plus, elections in New Jersey and Virginia could decide the future of the Democratic Party, and Nick Fuentes touts his victory over JD Vance. Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2310 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Join us now during our exclusive Deal of the Decade. Get everything for $7 a month. Not as fans. As fighters. Go to http://www.DailyWire.com/Subscribe to join now. Finally, Friendly Fire is here! No moderator, no safe words. Now available at https://www.dailywire.com/show/friendly-fire Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: Policygenius - Head to https://policygenius.com/SHAPIRO to get your free life insurance quotes and see how much you could save. Shopify - Sign up for your $1-per-month trial and start selling today at https://Shopify.com/shapiro PreBorn! - Donate today and help save babies from abortion at https://preborn.com/BEN or dial #250 keyword 'BABY' NetSuite - Download the free business guide, Demystifying AI, at https://NetSuite.com/SHAPIRO Quo - Get 20% off of your first 6 months at Quo.com/BEN Lumen - Go to https://lumen.me/SHAPIRO to get an additional 10% off your Lumen. Kalshi - Visit https://kalshi.com today! - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53  Follow on Instagram: https://bit.ly/3QtuibJ  Follow on Facebook: https://bit.ly/3TTirqd  Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy Learn more about your ad choices. Visit megaphone.fm/adchoices

Send us a textHow mitochondria travel between cells and how this hidden communication shapes metabolism, immunity, and even potential therapies.Episode Summary: Dr. Jon Brestoff talks about mitochondrial dynamics inside cells, their transfer between unrelated cells (distinct from inheritance during division), and its roles in adipose tissue communication, macrophage cleanup, and systemic metabolic signaling; they explore how high-fat diets disrupt this process, potential hormetic benefits, therapeutic mitochondria transplantation for diseases like Leigh syndrome and obesity, and broader immunometabolism crosstalk.About the guest: Jon Brestoff, MD, PhD is an associate professor of pathology and immunology at Washington University School of Medicine in St. Louis, where he directs the Initiative for Immunometabolism.Discussion Points:Mitochondria per cell range from ~100-5000; they move via fusion/fission, vertical inheritance (cell division), or horizontal transfer without division.Transfer mechanisms: free release, extracellular vesicles, or tunneling nanotubes using cytoskeleton transport.In healthy fat tissue, adipocytes routinely donate mitochondria to macrophages for degradation (quality control); high-fat (lard-based, long-chain FA) diets block macrophage uptake, diverting mitochondria to other organs.Diverted mitochondria may induce “mito-hormesis” (mild oxidative stress boosting antioxidants) or signal adipocyte metabolic status inter-organ.Mitochondria transplantation shows promise in animal models for ischemia-reperfusion, obesity, and mitochondrial diseases.Immune cells prefer glycolysis but have low mitochondrial biomass; transplanted mitochondria tilt T-cells toward anti-inflammatory regulatory phenotype.Circulating cell-free mitochondria rival immune cell numbers.Obesity inflammation stems from dying oversized adipocytes releasing lipids/mitochondria, forming crown-like structures with pro-inflammatory macrophages.Leigh syndrome from genetic mutations disrupting the electron transport chain.Transfer may be an evolutionary relic of endosymbiosis; cells may selectively use exogenous mitochondria like a “generator” during metabolic crisis.Reference Paper:Study: The power and potential of mitochondria transferRelated Episode:M&M 260: Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha MuruganSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Lumen is once again raising rates for out-of-term services, with some customers now facing increases as high as 30% to 40%.  These changes put enterprise clients in a tough spot, often forcing them to choose between costly renewals or seeking alternatives in a competitive market.  In this 6-minute podcast, Theresa Knutson from TC2 joins Tony Mangino to break down what's driving these price hikes, how they impact your organization, and what strategies you can use to protect your bottom line. If you would like to learn more about our experience in this space, please visit our IT Cost Management and Strategic Sourcing webpages.

Nous sommes nombreuses à connaître des fantasmes de violence, et de soumission. Parfois, à ressentir de l'excitation devant des scènes de violences sexuelles dans les films, les livres, les séries. Ca n'a rien de contradictoire. C'est plutôt très logique. Nous grandissons dans la culture du viol et de l'inceste. On nous apprend à désirer la violence. Mais qu'est-ce qu'on fait de ça pour se sentir justement alignée avec soi même, ses aspirations, ses valeurs et ses désirs ? Est-ce qu'on essaye de ne plus penser à ses fantasmes, de les garder pour soi, dans un coin de notre tête ?  De les remplacer ? Est-ce qu'on les met en pratique, on les joue, on s'en moque ?Qu'est ce que tout cela raconte ?C'est ce que je me suis demandé dans cet épisode aux côtés de femmes qui pratiquent le BDSM et d'autres qui cherchent des voies pour désirer en dehors de la violence.Avec :- Nadia et Pauline- Rebecca Levy Guillain, sociologue et sexothérapeuthe- Daria Sobocinska, sociologue- Aurore Vincenti, linguiste- Myriam Bahaffou, chercheuse en philosophie et militante écoféministe décolonialeTextes : - Histoire d'O, Pauline Réage- Les aventure de China Iron, Gabriela Cabezón Cámara- L'endroit de mon trouble, Lumen- Sélection prix Gouincourt 2025Pour aller plus loin :- Pour une érotique du sensible, Aurore Vincenti- Éropolitique, Myriam Bahaffou- Féminisme et fantasme de soumission, Céline Bercion- Fantasmes au féminin, Maud Serpin- MeToo or not MeToo , Rebecca Levy Guillain- Les relations non conjugales, Daria SobocinskaRemerciements :Je remercie tout particulièrement : Nadia et Pauline, Lou des soirées "Monts et Merveilles" et Aude pour le courage des témoignages et la confiance accordée.Merci aussi à Maud Serpin pour les mises en contacts, à Claire Alquier, à Sophie, à toutes celles contactées pour l'émission. Enregistrements septembre 2025 Prise de son, montage, textes et voix Charlotte Bienaimé Réalisation et mixage Annabelle Brouard Lectures Laure Giappiconi Accompagnement éditorial Sarah Bénichou Community Manager Meyrélie Milhavet Illustrations Anna Wanda Gogusey

Send us a textA biophysical rethink of life, health, and disease through the lens of the Energy Resistance Principle (ERP).Episode Summary: A reframe of biology as energy flow through resistance rather than mere molecular machinery, introducing the Energy Resistance Principle (ERP): life requires a Goldilocks balance of electron flow from food to oxygen via mitochondria; too much or too little resistance drives aging, disease, and death. Explain mitochondria as energy transformers, link ERP to insulin resistance, psychiatric disorders, and healing, and explore health as a dynamic field-like state optimized by flux modulation.About the guest: Nirosha Murugan, PhD is a biophysicist studying how physical signals pattern biology to decode and reprogram health; Martin Picard, PhD is a mitochondrial psychobiologist at Columbia University, exploring how mitochondrial energy dynamics connect to human experiences, health, and healing. They collaborate on biophotons, light emission, and multi-scale energy signaling.Discussion Points:Mitochondria transform electrons from food into versatile electricity via proton gradients.Energy Resistance Principle: transformation needs resistance; chronic high resistance causes dissipative heat, damage, aging.GDF15 cytokine signals mitochondrial stress to brain, triggering energy conservation/mobilization.Insulin resistance: adaptive defense against electron overload, reversible by fasting/exercise.Psychiatric illness: excess brain energy resistance; exercise, keto, psychedelics redistribute flux.Health: dynamic optimization of energy resistance, not absence of disease.Healing: daily recovery from micro-damage via balanced resistance.Future: energy-based diagnostics/therapies (light, TMS) over molecule-only drugs.*Not medical advice.Reference Paper: The energy resistance principleRelated Episode:M&M 70: Mitochondria, Aging, Cellular Energy, Metabolism, Gray Hair Reversal & Brain-Body Communication | Martin PicardSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

In this episode of LIGHT TALK with The Lumen Brothers and Sister, the Lumen family interviews Broadway lighting designer Justin Townsend. In this episode, Justin, Ellen, Steve, and Dennis discuss: Justin's journey as a lighting designer; Teaching hand drafting; Working with Jonathan Groff and Alex Timbers; A trip to Home Depot for Mini 10's; "Bat Boy"; Teaching at NYU; "Here Lies Love"; Collaborating artistically with associates and programmers; Growing up with opera in the house; Playing with light; Staying Dangerous; Being ready to pivot; 48 Dimmers in a Basement; Learning how to work with a large team; Justin's panel at LDI; Challenges of mixing family life with work; and Lessons for young lighting designers of today.   Nothing is Taboo, Nothing is Sacred, and Very Little Makes Sense.

Esta mañana del 24 de octubre, Día Internacional de las Bibliotecas, nuestro bibliotecario Antonio Martínez Asensio nos trajo a una escritora que está impactando con su primera novela. Es la gallega Lucía Solla Sobral, autora de 'Comerás flores', editada por Libros del Asteroide. Es un thriller psicológico sobre un tema la violencia machista, pero con un lenguaje tan poético y un personaje con el que empatizas tanto que a la vez que sufres, le pones nombre a lo que todos vemos y no somos capaces de denunciar.  Lucía, además de donarnos su libro, nos dejó uno de los que más le ha gustado en su vida:  'Tengo miedo torero' de Pedro Lemebel (Las Afueras). Pero antes de la entrevista con Lucía Solla Sobral, Antonio Martínez Asensio nos contó en tres minutos  'Fahrenheit 451' de Ray Bradbury (DeBolsillo), un clásico brutal. Tambié nuestro bibliotecario nos dejó uno de sus libros de su programa 'Un libro , una hora', 'Los bienes de este mundo' de Irene Némirovsky (Salamandra). Y ya en el capítulo de novedades,  Pepe Rubio nos trajo 'Inventario de siembra' de Thais Gamaza (Editorial  16)  y 'Hansel y Gretel' de Stephen King y Maurice Sendak (Lumen). Pascual Donate en su búsqueda de libros abandonados en la redacción de la SER recuperó un poemario 'Ojalá joder' de Escandar Algeet (Ya lo Dijo Casimiro Parker) . Y terminamos con las donaciones de los oyentes que fueron: 'Tan poca vida' de Hanya Yanagihara (Lumen), 'Crónicas marcianas" de Ray Bradbury (páginas de espuma), 'Doña Rosita la soltera' de Federico García Lorca (Austral)  y 'Mi enemigo mortal' de Willa Cather (Alba Editorial). 

Tensormesh uses an expanded form of KV Caching to make inference loads as much as ten times more efficient. Plus, Palantir said on Thursday it had struck a partnership with Lumen Technologies that will see the telecommunications company using the data management company's AI software to build capabilities to support enterprise AI services. Learn more about your ad choices. Visit podcastchoices.com/adchoices

DHV2 & Naimo – Tribe is the third release on NOFEAR! Musik. One of the rising talents of the Spanish Techno scene, DHV2, joins forces with fellow Catalan producer Naimo to deliver a three-track EP that moves between Techno and Hardgroove. Expect tribal elements, recognizable vocal samples and heavy-hitting kicks, shaping a powerful and energetic release that continues the label's mission: fearless, club-ready music built for the dancefloor. https://bit.ly/nfm003 Follow: https://www.instagram.com/nofearmusik https://www.instagram.com/dhv2__/ https://www.instagram.com/naimo_producer/

DHV2 & Naimo – Tribe is the third release on NOFEAR! Musik. One of the rising talents of the Spanish Techno scene, DHV2, joins forces with fellow Catalan producer Naimo to deliver a three-track EP that moves between Techno and Hardgroove. Expect tribal elements, recognizable vocal samples and heavy-hitting kicks, shaping a powerful and energetic release that continues the label's mission: fearless, club-ready music built for the dancefloor. https://bit.ly/nfm003 Follow: https://www.instagram.com/nofearmusik https://www.instagram.com/dhv2__/ https://www.instagram.com/naimo_producer/

DHV2 & Naimo – Tribe is the third release on NOFEAR! Musik. One of the rising talents of the Spanish Techno scene, DHV2, joins forces with fellow Catalan producer Naimo to deliver a three-track EP that moves between Techno and Hardgroove. Expect tribal elements, recognizable vocal samples and heavy-hitting kicks, shaping a powerful and energetic release that continues the label's mission: fearless, club-ready music built for the dancefloor. https://bit.ly/nfm003 Follow: https://www.instagram.com/nofearmusik https://www.instagram.com/dhv2__/ https://www.instagram.com/naimo_producer/

Graceann F. Beckett preaches for the Thirtieth Sunday in Ordinary Time, inviting us to consider how humility, honesty, and trust in God's love open the way to true justification:"God desires relationship, to be able to draw near, and this desire is certainly not dependent upon a grand presentation of one's most pious actions or traits."Graceann Beckett is a M.T.S. student at Boston College Clough School of Theology and Ministry (CSTM), where she is also an editor for "Lumen et Vita," the student academic journal at the CSTM. Her academic interests include ecclesiology, Appalachian studies, and ethnography. In addition, her work with the Dorothy Day Guild and the Catholic Worker Movement has shaped her life, faith, and academic pursuits significantly.Visit www.catholicwomenpreach.org/preaching/10262025 to learn more about Graceann, to read her preaching text, and for more preaching from Catholic women.

In this episode, Renee and Karen chat with Bethany Kern about her new art history and appreciation books called Lumen, A Guide to the Elements of Art through Time. The first volume (of seven) on line was published last year, and the second, on space, is hot off the presses. Listen as Bethany describes the process of choosing artists and their work, how the volumes are structured, and how you can use them in your homeschool. Get these beautiful books now!Lumen, A Guide to the Elements of Art through Time Hosted on Acast. See acast.com/privacy for more information.

What does it take to roll out Copilot Studio at scale? Andrew Gaskins of Lumen joins the podcast to unpack how admins can lead innovation through governance. From zone strategies to CoE reviews, Andrew walks us through the battle-tested blueprint that helped Lumen deploy thousands of agents while keeping costs in check. If you're wondering how to balance freedom and control in your agent strategy, this episode is your playbook.   Andrew's previous episode: https://thelowcodeapproach.podbean.com/e/the-power-of-building-a-community-w-andrew-gaskins/

Send us a textHow artificial light impacts female menstrual cycles and their relationship to lunar cycles of the moon.Summary: Dr. Förster talks about how biological clocks, including circadian, tidal, lunar, and annual cycles, regulate behaviors in various species, with a focus on lunar cycle effects on human menstrual cycles. They explore historical and modern data suggesting that menstrual cycles may synchronize with lunar phases, a phenomenon potentially disrupted by modern artificial lighting, particularly blue light from LEDs post-2010. The conversation also covers circadian rhythm mechanisms in fruit flies and humans, highlighting the role of light and neuropeptides in maintaining biological synchrony.About guest: Charlotte Förster, PhD is a senior professor at the University of Würzburg specializing in chronobiology, particularly circadian rhythms in fruit flies, and has recently explored lunar cycle influences on human menstrual cycles.Discussion Points:Biological Clocks: Various clocks (circadian, tidal, lunar, annual) regulate behaviors; circadian clocks manage 24-hour cycles, while lunar clocks influence reproduction in marine species like corals and Christmas Island crabs.Lunar Cycle & Menstruation: Historical data (pre-2010) showed many women's menstrual cycles synchronized with lunar phases (full or new moon), but this decreased post-2010, possibly due to blue light from LEDs disrupting biological rhythms.Blue Light Impact: Blue light from modern devices mimics daylight, potentially desynchronizing circadian and lunar clocks, with melanopsin in the eyes playing a key role in light sensitivity.Winter Synchronization: Menstrual cycle synchrony with lunar phases is stronger in winter, particularly January, possibly due to brighter moonlight or gravitational effects when Earth is closest to the Sun.Circadian Mechanisms: In fruit flies, 240 neurons manage circadian rhythms via clock genes with a 24-hour feedback loop, conserved in humans, where neuropeptides regulate slower, sustained rhythms.Health Implications: Disrupted circadian rhythms can desynchronize body clocks, impacting digestion, immunity, and increasing risks of cardiovascular issues, obesity, and cancer.Lifestyle Tips: To maintain synchrony, maximize daytime light exposure, minimize nighttime blue light, time meals appropriately, and exercise during the day, not late at night.Reference paper:Study: Synchronization of women's menstruation with the Moon hasSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Hablamos de Anidan minerales (Ed. Pre-Textos), el primer y brevísimo poemario de la escritora madrileña Julia Viejo, a la que hasta el momento teníamos por narradora, pero que se acaba de descubrir también como poeta gracias a este libro ingrávido a la vez que hondo, inteligente pero nunca resabiado, de una candidez que nos retrotrae a una edad anterior.Luego, Ignacio Elguero pone dos títulos inclasificables sobre la mesa: La pregunta 7 (Ed. Libros del asteroide), del australiano Richard Flanagan en traducción de Catalina Martínez Muñoz, y El abc de Byobu (Ed. Lumen), de la escritora uruguaya y Premio Cervantes Ida Vitale.Además, Javier Lostalé abre su ventanita a La duermevela es una lejanía (Ed. Reino de Cordelia) el nuevo poemario del periodista y escritor Fernando del Val, en el que se percibe su honda formación clásica, así como sus conocimientos filosóficos y su capacidad para interrelacionar todas las artes.En Peligro en la Estación nuestro colaborador Sergio C. Fanjul nos recomienda Historias fantásticas de islas verdaderas (Ed. Gatopardo), volumen en el que el escritor genovés Ernesto Franco se inventa el personaje de un rudo marinero para proponernos un viaje por algunas de las ínsulas más curiosas del mundo.Terminamos el programa junto a Mariano Peyrou, que esta vez nos habla de Idem lo mismo (Ed. Kriller), una selección de piezas breves de la escritora Gertrude Stein, pieza clave de esa riquísima línea de poesía norteamericana que todavía hoy se alimenta de sus ideas, tan estimulantes como divertidas.Escuchar audio

Send us a textThe genetic & developmental changes behind bipedalism & human anatomy.Wide release date: October 15, 2025.Episode Summary: Dr. Terence Capellini talks about the evolution of bipedalism in humans, exploring when and why it emerged, the anatomical changes required, and the genetic mechanisms behind these adaptations. They discuss how environmental shifts, like shrinking forests, drove the need for upright walking, the gradual skeletal changes in the pelvis and limbs, and how these changes may have facilitated larger brain sizes. Capellini highlights the complexity of evolutionary processes, emphasizing the role of multiple genetic changes in regulatory regions rather than single genes.About the guest: Terence Capellini, PhD is a professor and chair of the Department of Human Evolutionary Biology at Harvard University. His research focuses on developmental genetics and human evolution.Discussion Points:Bipedalism likely became common ~3.5 million years ago with Australopithecus afarensis, with earlier hominins like Ardipithecus showing mosaic traits.Environmental changes, such as shrinking forests and expanding grasslands, created selective pressures favoring bipedal locomotion.The human pelvis evolved to be shorter, wider, and curved, with muscles like the gluteus medius shifting to stabilize upright walking.Genetic changes in non-coding regulatory regions, not protein-coding genes, drive the developmental shifts in pelvic growth, with hundreds of small-effect changes involved.Bipedalism may have widened the birth canal, potentially enabling the evolution of larger brains in later hominins like Homo erectus.Humans have more slow-twitch muscle fibers than chimpanzees, supporting endurance activities like long-distance running, possibly linked to energetic trade-offs with brain growth.Shoulder and arm adaptations for throwing and tool use evolved more gradually, becoming prominent ~2 million years ago with Homo erectus.Reference paper:Study: The evolution of hominin bipedalism in two stepsRelated content:M&M 171: Comparative Brain Evolution: Mammals, Primates & Humans | Robert Barton*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Struggling with a sluggish Windows 11 laptop or curious about the latest accessibility tech? Steven Scott and Shaun Preece explore remote troubleshooting, the slowdown mystery, and brand-new partnerships from Be My Eyes with BT, EE, Tesco, and Sony. Plus, a look at Dot Lumen's AI-powered mobility glasses, Apple TV's rebrand, and why Shaun is side-eyeing his Apple Watch upgrade.In this episode of Double Tap, Shaun returns from his brief, tissue-filled hiatus to join Steven for a lively dive into both tech challenges and accessibility wins. The duo unpack:A real-world Windows 11 performance headache, from bloatware removal to NVDA remote troubleshooting How Be My Eyes is transforming customer support with BT, EE, Tesco in-store pilots, and Sony product support Dot Lumen's AI-driven glasses and what they could mean for blind mobility worldwide Apple's quiet rebrand of Apple TV+, the end of the Clips app, and speculation on future hardware Steven's decision to swap his Series 11 for the louder, more capable Apple Watch Ultra 3From remote PC control tips to reflections on the future of accessible shopping and navigation, this episode blends practical advice with personal tech trials.Relevant LinksBe My Eyes: https://www.bemyeyes.comDot Lumen: https://www.dotlumen.comNVDA Remote: https://www.nvaccess.orgRemote Incident Manager: https://www.perkinsaccess.org/rimApple Accessibility: https://www.apple.com/accessibility Find Double Tap online: YouTube, Double Tap Website---Follow on:YouTube: https://www.doubletaponair.com/youtubeX (formerly Twitter): https://www.doubletaponair.com/xInstagram: https://www.doubletaponair.com/instagramTikTok: https://www.doubletaponair.com/tiktokThreads: https://www.doubletaponair.com/threadsFacebook: https://www.doubletaponair.com/facebookLinkedIn: https://www.doubletaponair.com/linkedin Subscribe to the Podcast:Apple: https://www.doubletaponair.com/appleSpotify: https://www.doubletaponair.com/spotifyRSS: https://www.doubletaponair.com/podcastiHeadRadio: https://www.doubletaponair.com/iheart About Double TapHosted by the insightful duo, Steven Scott and Shaun Preece, Double Tap is a treasure trove of information for anyone who's blind or partially sighted and has a passion for tech. Steven and Shaun not only demystify tech, but they also regularly feature interviews and welcome guests from the community, fostering an interactive and engaging environment. Tune in every day of the week, and you'll discover how technology can seamlessly integrate into your life, enhancing daily tasks and experiences, even if your sight is limited. "Double Tap" is a registered trademark of Double Tap Productions Inc. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Lumen es uno de los sellos de mayor prestigio en España, con un catálogo que incluye a Virginia Woolf, Doris Lessing, a Umberto Eco o Alice Munro, por ejemplo, y autoras más contemporáneas. La última en entrar en esa lista es una lorquina, Inma Pelegrín, que ha ganado el premio Lumen de novela con un thriller rural donde la protagonista es una perra llamada Sombra y su relación con Gabi, el narrador de la historia. Fosca es una obra que nos ha encantado, muy original. ¿Qué tendrá la ciudad de Nueva York para atraparnos con ese poder magnético que solo parece tener ella, y ningún otro sitio del mundo? Sergi Reboredo, viajero que siempre tiene la pluma y la cámara listas para enseñarnos los mejores rincones del planeta, viaja esta vez a la Gran Manzana. El libro, publicado primorosamente por Anaya Touring, es una delicia.Y conocemos a un personaje que parece de novela, con una vida atormentada donde los momentos de felicidad fueron pocos, y que le sirvió de sustrato para escribir cuentos que la llevaron a ser equiparada a Carver. Su nombre, Lucia Berlin. Manual para mujeres de la limpieza es uno de los mejores libros de relatos que jamás ha caído en nuestras manos. Detrás de tanto talento hubo oscuridad. Y entramos en ella. En Alfaguara está toda su obra.Y además, las manías de García Márquez. ¿Por qué quería tener siempre lejos a los caracoles o a los pavos reales?En la sección de Audiolibros, Elizabeth Strout.

Welcome back for a quick-hitter from Zak and Brad, just ahead of the Sounder's rescheduled home match against Real Salt Lake. The guys preview that one, go through the limited list of players available and try and predict how the team will line up at Lumen. Some major retirement announcements to discuss as well, including Steve's old Akron friend and MLS star Darlington Nagbe. For fans attending the October 11th match, head over to Olympic Hall for a live podcast experience with both Brad Evans and Steve Zakuani!

What happens when you put a mic in front of HR leaders and ask them for their unfiltered takes on AI?In this episode, Daniel and Stephen recap their trip to HR Tech — where they recorded 12 quick-hit “AI Confessions” from folks they met on the conference room floor. From agentic workflows and custom GPT chaos to the real blockers slowing down AI adoption, this one's packed with candid insights from the front lines.You'll hear what HR leaders from companies like Lumen, Articulate, and Airbnb.---- Sponsor Links:

Send us a textThe biological roots of sleep are tied to mitochondrial metabolism.Episode Summary: Dr. Gero Miesenböck discusses the evolutionary and metabolic basis of sleep, exploring how mitochondrial energy production in neurons, particularly in fruit flies, drives the need for sleep to manage harmful byproducts like reactive oxygen species and lipid peroxides. They discuss how sleep-inducing neurons sense these byproducts, the role of mitochondrial dynamics, and the broader implications for why all animals, from jellyfish to humans, require sleep. The conversation also touches on how body size and metabolism influence sleep needs across species.About the guest: Gero Miesenböck, MD is a professor of physiology at the University of Oxford, renowned for his pioneering work in optogenetics and his research on the neurobiology of sleep using fruit flies and mice.Discussion Points:Sleep is universal across animals, even in jellyfish without centralized brains, suggesting a fundamental metabolic purpose tied to mitochondrial energy production.Mitochondria produce energy efficiently using oxygen but generate reactive oxygen species that can damage cells through lipid peroxidation, necessitating sleep to repair this damage.Sleep-inducing neurons in fruit flies contain sensors that track lipid peroxidation products, acting like a digital memory to signal when sleep is needed.Smaller animals with faster metabolisms, like mice, require more sleep and have shorter lifespans due to higher oxygen consumption and oxidative stress.Mitochondrial diseases in humans often cause intense tiredness, likely due to increased electron leaks in the mitochondrial energy production process.The evolutionary origin of sleep likely stems from the oxygen revolution 2.5 billion years ago, enabling complex life but requiring mechanisms like sleep to manage metabolic side effects.Caloric restriction reduces sleep need by lowering the production of harmful metabolic byproducts, supporting the link between metabolism and sleep.Reference paper:Study: Mitochondrial origins of the pressure to sleepRelated content:M&M 12: Organisms, Cities, Companies & the Science of Scale | Geoffrey West*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

In this episode, we sit down with Nadia Ali, a health coach and digital nomad, to explore her transformative journey from battling disordered eating to embracing biohacking and metabolic flexibility. Nadia shares her insights on maintaining health while traveling the world, the impact of Lumen on her fitness journey, and the importance of trusting the process. Tune in for an inspiring conversation filled with practical tips and personal stories that highlight the power of resilience and self-discovery.

Parita scoppiettanta ma come spesso accadade per gli incontri al Lumen field, arriva una sconfitta.

Send us a textThe surprising link between oral bacteria and heart disease.Episode Summary: Dr. Pekka Karhunen explains the connection between oral bacteria, cholesterol, and cardiovascular disease, discussing how oxidized LDL cholesterol triggers inflammation in arteries, how bacteria from the mouth can infiltrate arterial plaques to form biofilms, and the implications for heart disease prevention through lifestyle changes like better oral hygiene.About the guest: Pekka Karhunen, MD, PhD is a medical doctor and forensic pathologist with decades of experience, specializing in cardiovascular diseases. He has created a unique biobank of coronary arteries from over 10,000 autopsies conducted in Finland. His research focuses on the role of bacteria in atherosclerosis, particularly through studying coronary artery plaques.Discussion Points:Cholesterol is essential for life, but oxidized low-density lipoprotein (LDL) cholesterol is seen as a foreign substance by the immune system, leading to chronic inflammation in coronary arteries.Macrophages ingest oxidized LDL, turning into dysfunctional foam cells that contribute to plaque buildup, known as atheromas, in arteries.Plaque rupture, potentially caused by increased pressure from cholesterol accumulation or hemorrhage within the plaque, can trigger heart attacks.Bacteria, especially from the mouth, can enter arterial plaques via bacteremia (e.g., from dental procedures) and form biofilms, evading immune detection.Biofilms in plaques, made of extracellular matrix like polysaccharides, protect bacteria and may contribute to plaque instability or calcification over time.Poor oral hygiene is linked to higher cardiovascular disease risk, as bacteria from dental infections can enter plaques, suggesting dental care as a preventive measure.Karhunen's research found oral bacteria, like Viridans streptococci, in coronary plaques, with unpublished data also detecting gut and skin bacteria, indicating diverse bacterial involvement.Related content:M&M 247: Cholesterol: Immune Benefits, Heart Health, Statins & Research Malpractice | Uffe Ravnskov*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Join us as we dive into Maureen's inspiring journey with Lumen. From battling weight gain and early perimenopause to discovering a sustainable lifestyle change, Maureen shares her challenges, triumphs, and the surprising lessons learned along the way. Discover how she embraced real food, overcame self-doubt, and found a supportive community that helped her lose 50 pounds and transform her life. Tune in for an empowering conversation about resilience, self-care, and the power of trusting the process.

In this episode of the Open Hardware Manufacturing Podcast, Stephen and Lucy talk about what it's really like to advertise in the open hardware world. From running social media ads to trying out print campaigns, they share what worked, what didn't, and what they learned along the way.They touch on things like figuring out who your audience actually is, why selling machines like the Lumen pick and place takes patience, and how good messaging and customer feedback make all the difference. Instead of chasing quick wins, they dig into how brand awareness can matter more than immediate sales.You'll hear them cover:Marketing vs. advertising and why the difference mattersHow to understand what customers need (and how to show you can solve it)The tricky part of measuring ad resultsSocial media, search ads, sponsorships, and where they fitExamples of ad campaigns that hit the mark, and ones that missed---Join the conversation and share your thoughts at hardware.cafe.Do you have any questions, comments, or topic suggestions? Email us at podcast@opulo.io. We'd love to hear from you!To learn more about what we do, visit Opulo.io.To see everything else we do, including social media, visit Opulo.start.page.O.H.M. Podcast Merch is now here!Intro song:Complicate Ya - Otis McDonald (Creative Commons Attribution License) Hosted on Acast. See acast.com/privacy for more information.

Send us a textHow nutrition and medications impact mitochondrial health.Wide release date: October 1, 2025.Episode Summary: Dr. Chris Masterjohn talks about the intricate relationships between nutrition, prescription drugs, and mitochondrial health, discussing how molecules like acetaminophen and SSRIs affect the body beyond their intended purposes, particularly impacting inflammation and energy metabolism. The discussion gets into the broader implications of serotonin outside the brain, the side effects of commonly used medications, and the importance of personalized nutritional strategies to optimize mitochondrial function.About the guest: Chris Masterjohn, PhD holds a doctorate in nutritional sciences and is a co-founder of Mitome, a company focused on mitochondrial testing to optimize cellular energy production.Discussion Points:Acetaminophen & Inflammation: Acetaminophen (Tylenol) may contribute to chronic low-grade inflammation by blocking both the initiation and resolution of inflammation, potentially linked to health issues like autism when used during pregnancy.Serotonin's Role Beyond the Brain: Approximately 95% of serotonin is found in the gut, regulating motility, with SSRIs causing side effects like nausea due to increased extracellular serotonin.SSRIs & Mitochondrial Function: SSRIs disrupt serotonin uptake into cells, reducing mitochondrial melatonin production, which impairs the body's ability to handle hypoxic stress and produce ATP efficiently.Statins & Mitochondrial Impact: Statins, used to lower cholesterol, inhibit the mevalonate pathway, affecting not just cholesterol but also CoQ10 and vitamin K2, crucial for mitochondrial function, potentially leading to side effects like myopathy.Mitochondrial Testing with Mitome: Masterjohn's company, Mitome, uses cheek swab tests to measure mitochondrial respiratory chain activity, providing personalized dietary and lifestyle recommendations to optimize cellular energy production.Nutrition & Mental Health: Masterjohn shares his personal experience of severe mental health issues on a vegan diet, which improved dramatically with a nutrient-dense diet rich in organ meats, highlighting individual nutritional needs.Energy Metabolism's Universal Role: Mitochondrial ATP production governs everything from daily energy levels to long-term health, with personalized testing helping identify and address specific bottlenecks.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Joaquin Cordero is the Founder and President of Lumen, a communications company that provides creative and advertising services including media commercialization, 360-degree agency work, BTL, print, and point-of-purchase services. He founded Lumen in 2009 in Guatemala, expanding it into El Salvador and Honduras and serving both local and global brands. Joaquin has also founded over eleven companies, and serves in leadership roles in the Entrepreneurs' Organization, including Global Board Director and EO Global Chair-Elect. In this episode… Stepping away from the day to day demands of your own company can feel risky when growth and stability are on the line. Yet some of the most successful entrepreneurs insist that leading beyond their business creates new energy and ideas. How can taking on outside leadership roles actually spark innovation and strengthen resilience? According to Joaquin Cordero, a global entrepreneurial leader, dedicating time to serve in volunteer leadership opens doors to fresh perspectives and powerful relationships. He highlights how working with peers who run their own companies forces you to lead by influence and build trust instead of relying on authority. This approach has helped him foster a stronger company culture and inspire long term loyalty among his team. Joaquin's experiences prove that growth often happens when you challenge yourself beyond your own organization. In this episode of the Smart Business Revolution Podcast, John Corcoran speaks with Joaquin Cordero, Founder and President of Lumen, to talk about why stepping outside your business sparks innovation and resilience. They explore how serving in global leadership roles fuels personal and professional growth and how trust and collaboration transform company culture. Joaquin also shares lessons from navigating unexpected challenges and building long-term client relationships.

Send us a textGenetic & environmental factors that affect brain health, including why people age faster in outer space. (Note: technical difficulties affected the audio quality of this recording somewhat)Episode Summary: Dr. Jacob Raber explains how apolipoproteins, particularly ApoE, influence brain health and disease risk; their role in cholesterol metabolism, Alzheimer's disease, and responses to environmental stressors like radiation and viral infections; interplay between genetics, diet, and lifestyle factors, highlighting how these affect cognitive function and resilience to stress; research into space radiation, the gut-brain axis, and potential interventions for neurodegenerative diseases.About the guest: Jacob Raber, PhD, is a neuroscientist at Oregon Health & Science University (OHSU) in Portland, where he leads a lab studying genetic and environmental influences on brain health, particularly using mouse models with human genes.Discussion Points:Apolipoproteins (ApoE2, E3, E4) are proteins involved in cholesterol and lipid metabolism in the brain, with ApoE4 increasing risks for Alzheimer's and cardiovascular disease.ApoE4 carriers may face higher risks for cognitive decline but could have advantages in specific contexts, like fertility or certain infections.Environmental stressors, such as space radiation and viral infections like West Nile, can exacerbate oxidative stress, impacting brain health.The gut microbiome influences brain function indirectly via the gut-liver-brain axis, with ongoing studies exploring its role in Alzheimer's and traumatic brain injury.Lifestyle factors like diet, exercise, and sleep are critical for brain health, potentially mitigating genetic risks like ApoE4.Statins, commonly used for cholesterol management, may impair learning in healthy animals, suggesting context-dependent effects.Research into space radiation reveals potential therapeutic applications, such as using heavy ion radiation for cancer treatment.Genetic variations, including ethnicity and sex, influence ApoE-related disease risks, with women and certain populations showing higher Alzheimer's susceptibility.Chronic low-level stressors, like air pollution, may pose greater risks to brain health than acute exposures due to insufficient activation of protective mechanisms.Related content:M&M 165: PUFAs in Brain Health & Disease, Dietary Fats, Brain Lipids, Nutrition | Richard Bazinet*Not medical adviceSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

In this episode,  we sit down with Amanda Smyth, a vibrant Londoner who splits her time between the UK and Turkey.  Amanda shares her inspiring journey from overtraining and yo-yo dieting to discovering a balanced lifestyle with the help of Lumen.  Learn how Amanda transformed her approach to health, embraced metabolic flexibility, and found joy in fitness.  Whether you're looking to improve your metabolism or simply seeking motivation to live life to the fullest,  Amanda's story offers valuable insights and encouragement.  Tune in to explore the power of patience, community, and self-discovery on the path to wellness.

Today, Fiona chats to Lucy Lumen - photographer, YouTuber, content creator, and creative business mentor who has built a thriving online business alongside her husband.In this episode, you'll learn:• How Lucy went from working in hospitality for 10+ years to accidentally building a photography and videography business• Why she decided to pivot away from client work and go all-in on YouTube content creation• Her process for creating 8 YouTube videos per month across two channels while managing Substack and social media• How sponsorships (not ad revenue) make YouTube financially sustainable as a full-time career• The reality of working with your spouse and managing business partnerships• Why developing a distinct personal style is more important than technical perfection in the age of AILucy shares honest insights about the realities of content creation, building a creative business, and how to turn your passion into sustainable income while maintaining work-life balance.A massive thank you to our sponsor and our fave AI tool, Poppy AI. Use FIONA at checkout for a discount Connect with My Daily Business:Instagram: @mydailybusiness_TikTok: @mydailybusinessEmail: hello@mydailybusiness.comWebsite: mydailybusiness.comConnect with Lucy LumenInstagram: @lucy_lumenSubtack: Love LucyYouTube: The Lucy Lumen ShowYouTube: Lucy LumenWebsite: lucylumen.com Resources mentioned:Join our AI Chat Group for small business ownersGroup CoachingMy Daily Business courses - mydailybusiness.com/courses ⭐️ GET MORE TIME BACK with our fave AI tool that has saved us HOURS. Use Poppy AI and code FIONA for a discount ⭐️ Need some inspiration and tips today? Check out our new book, Business to Brand: Moving from transaction to transformation now. Get started on a more successful and sustainable small business with our range of free tools at mydailybusiness.com/freestuff Want to know more about AI and how to harness it for your small businesS? Join our new monthly AI chat for small business owners. You can join anytime at www.mydailybusiness.com/AIchat Try out my fave AI tool, Poppy AI here and use discount code FIONA. Ever wanted to write your own book and build your brand authority or start your own podcast to connect with and grow your audience? Check out our How to Start a Podcast Course or How to Get Your Book Published Course at our courses page. Connect and get in touch with My Daily Business via our shop, freebies, award-winning books, Instagram and Tik Tok.

In this episode, Mardi Winder welcomes J. Lumen, a transformational trainer, certified master life coach, and bestselling author, for an honest and heartfelt conversation about moving forward when life throws you off course. J. opens up about her own story, which started with all the pieces in place. She had a long-term relationship, a “good” job, and a life that, from the outside, seemed just fine. But beneath the surface, things were far from okay. She describes feeling drained and trapped, responsible for everything, and convincing herself she had to tough it out until life magically improved.Things took an unexpected and frightening turn after she ended her relationship, when her ex-boyfriend showed up out of the blue and held her hostage in her home. She shares how the situation quickly escalated to a traumatic, life-altering ordeal. J. talks candidly about how there were no classic warning signs, sharing her experience as a cautionary tale.Rather than staying stuck in fear or regret, J. explains how she used the experience to hit reset on her life. She and Mardi discuss finding happiness by reconnecting with your core values, remembering what used to bring you joy, and realizing you've already made it through challenges before. They make it clear that no one has to have everything figured out before taking the first step. Instead, J. encourages exploring new interests, giving yourself space to mess up and learn, and trusting that confidence grows from action and curiosity, not perfection.Throughout the conversation, J. brings warmth and humor, reminding listeners that big life changes don't have to wait for a crisis. She also offers a free self-assessment tool to help people get started, showing that small steps and self-reflection can make a huge difference. This episode is full of supportive, practical advice for anyone feeling stuck or ready for a new chapter.About the Guest:J. Lumen is a Transformation Trainer, an International Speaker, Certified Master Life Coach and an International best-selling contributing author. J. knows first-hand how it feels to be silently dissatisfied with life. For her, this was feeling trapped in a relationship that was emotionally over and at a toxic job she hated but not seeing a way out or even what she wanted. Eventually breaking free from the relationship, she convinced herself of all the reasons to keep the job and figure out what she wanted. But two months later, an unexpected knock at her door changed her life drastically as the night ended with an arrest for attempted murder. Of her. Using her own transformation, she's on a mission to empower others to stop waiting for a life-altering event of their own and start living a life they'd never imagine possible, full of authentic joy and one they don't regret.For J.'s gift: https://resumeyourlife.com/To connect with J: Website: https://theunknownbucketlist.com/ LinkedIn: www.linkedin.com/in/J.lumen8 Instagram: https://www.instagram.com/theunknownbucketlist/About the Host: Mardi Winder is an ICF and BCC Executive and Leadership Coach, Certified Divorce Transition Coach, Certified Divorce Specialist (CDS®) and a Credentialed Distinguished Mediator in Texas. She has worked with women in executive, entrepreneur, and leadership roles, navigating personal, life, and professional transitions. She is the founder of Positive Communication Systems, LLC, and host of Real Divorce Talks, a quarterly series designed to provide education and inspiration to...

Send us a textHow maternal obesity epigenetically reprograms liver metabolism in offspring, predisposing them to metabolic disease.Episode Summary: Dr. Elvira Mass talks about macrophages, specialized immune cells that vary by tissue and play crucial roles beyond fighting infections, such as supporting organ function; Kupffer cells (liver macrophages) and how maternal obesity during pregnancy reprograms these cells in offspring, leading to fatty liver disease, fibrosis, and even cancer later in life, based on mouse studies showing epigenetic and metabolic shifts like increased glycolysis, with insights into developmental windows, nutritional mismatches, and broader implications for human health.About the guest: Elvira Mass, PhD, is a Professor of Developmental Immunology at the University of Bonn in Germany, where her lab focuses on the development and function of macrophages in various tissues.Discussion Points:Macrophages are diverse, tissue-specific cells that develop from embryonic precursors, performing unique tasks like providing growth factors in organs.Kupffer cells in the liver monitor blood from the gut and are exposed to maternal nutrients during fetal development.Maternal obesity (induced in mice via high-fat diets) programs offspring Kupffer cells epigenetically, leading to fatty liver in newborns and progression to diseases like cancer, even on normal diets.A "nutritional mismatch" between in utero high-fat exposure and postnatal normal diets worsens liver issues, as cells are "prepared" for excess high-fat intake but face scarcity.Key mechanism: Reprogrammed Kupffer cells overproduce apolipoproteins, driving excess lipid uptake in liver cells (hepatocytes), linked to transcription factor HIF-1α and a shift to inefficient glycolysis.Offspring from obese mothers show sex differences (males affected earlier) and persistent changes.Human parallels: Rising childhood fatty liver (once rare and tied to alcoholism) correlates with maternal obesity; studies like Dutch Hunger Winter show early gestational disruptions cause lifelong issues.Broader factors: Microbiome changes, specific fatty acids, and environmental toxins like microplastics may also reprogram macrophages; diets in studies vary beyond fat content, affecting results.Advice: Maintain consistent healthy habits pre- and during pregnancy; avoid sudden diet shifts, as developmental windows are critical for long-lived cells like Kupffer cells.Reference Paper:Study: Kupffer cell programming bySupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

In this episode, we dive into the inspiring journey of Henry Goode, who transformed his life with the help of Lumen. From overcoming physical setbacks to discovering the power of nutrition and community, Henry shares his personal story of resilience and determination. Join us as we explore the challenges and triumphs of his path to a healthier lifestyle, and learn how passion and purpose can drive lasting change.

The Seattle Seahawks had another dominant defensive performance this week against the Pittsburgh Steelers. We're celebrating a 31-17 win and some of the standout defensive performances. We discuss the emergence of Josh Jobe, Byron Murphy's impact, and how Mike Macdonald's coaching is shaping a resilient, and seemingly plug-and-play, defense. The impressive road win streak continues, but can they find a way to bring that success into Lumen? On offense, we highlight JSN's big play, the impact of Cooper Kupp, Ken Walker's explosive day, and the adjustments made by Klint Kubiak to get the play-action game rolling. Stick around for “Do Better” and “Better at Life” as we call out NFL conspiracies, production team blunders, and pay tribute to podcasting pioneer Todd Cochrane. Join our Sea Hawkers Podcast Pickem League - free prizes for weekly winners. Support the show Get in the Flock! Visit GetInTheFlock.com Or visit our website for other ways to support the show Subscribe via: Apple Podcasts | Spotify | Google Podcasts | YouTube | TuneIn | RSS Follow us on: Facebook | Twitter Listen on our free app for Android, iOS, Kindle or Windows Phone/PC Call or text: 253-235-9041 Find Sea Hawkers clubs around the world at SeaHawkers.org Music from the show by The 12 Train, download each track at ReverbNation    

Ellen Lampert-Greaux is the creative director for Live Design and LDI, an annual conference and trade show for entertainment design and technology professionals. She was on the five-person team that founded LDI in 1988, and has produced the conference and worked on special events for the show since its debut, working on all aspects from programming and promotion to operations, registration, and the attendee experience. She has also produced additional events for the Live Design/LDI franchise such as their Master Classes series for lighting, projection, audio, scenic design; the Envision Symposium; Backstage Las Vegas; and XLIVExLDI. She is also a triple award-winning writer - editor for Live Design (FOLIO: EDDY Award in 2021, 2022, and 2023) who specializes in entertainment design and technology, writing regularly for livedesignonline.com, as well as a freelance writer on technology and architectural lighting. She is also a co-host ( a Lumen sister) on the Light Talk podcast.She attended NYU where she was an English major, and Temple University for a BFA in television/film production. She earned her MFA in arts administration from Brooklyn College and was the publicity director of the Brooklyn Academy of Music (1979-1986). She is a theatrical press agent and a member of ATPAM/IATSE, as well co-founder in 1996 and co-director of the St. Barth Film Festival in the French West Indies, having run a similar festival in Avignon, France (1984-1993). She speaks fluent French and translates articles for magazines from French to English. This conversation explores the evolution and impact of LDI since its inception in 1988, highlighting the commitment of Light Switch to enhance experiences through design. The discussion covers various training opportunities, innovative events, and the importance of inclusivity and networking within the entertainment industry. The future of LDI is also addressed, emphasizing its role in fostering mentorship and professional growth.This Episode is brought to you by Lightswitch

Send us a textAging, tissue repair, and the longevity benefits of psilocin.Episode Summary: Dr. Louise Hecker discusses her research on tissue repair and regeneration, explaining how fibroblasts drive wound healing by forming scar tissue but fail to resolve properly with age, leading to fibrotic diseases like pulmonary fibrosis and liver cirrhosis; they discuss aging hallmarks such as oxidative stress and telomere shortening, and highlight Hecker's study showing psilocybin's active metabolite, psilocin, extends cellular lifespan in lab cultures by reducing oxidants and preserving telomeres, while monthly doses in aged mice improved appearance and survival rates.About the guest: Louise Hecker, PhD is an Associate Professor of Medicine at Baylor College of Medicine, specializing in repair and regeneration processes, particularly in aging and fibrotic diseases.Discussion Points:Fibroblasts are dormant cells that activate during injury to pull wounds closed and form scars, then de-differentiate or die; aging impairs this, causing persistent scarring and disease.Aging reduces the body's regenerative capacity; different organs vary in repair efficiency, with skin healing better than heart tissue.Oxidative stress, like "rust" in the body, accumulates with age due to imbalanced reactive oxygen species production and antioxidant defenses, contributing to cellular damage.Telomeres act as protective DNA caps that shorten with cell divisions, serving as a hallmark of biological aging; sirtuins are master regulators influencing aging processes.Hecker's in vitro study showed psilocin dose-dependently extended fibroblast lifespan by 29-50%, lowering oxidative stress below young cell levels and preserving telomeres.In aged mice (equivalent to 60-65 human years), monthly high-dose psilocybin (15 mg/kg) led to healthier appearance, regrown fur, and 80% survival when controls reached 50% mortality after 10 months.Psilocybin's effects may stem from serotonin receptors expressed in many cell types beyond the brain, suggesting broader anti-aging potential; future work explores mechanisms, optimal dosing, and applications for age-related diseases.Fungi like magic mushrooms represent an under-explored "kingdom" for medicine, with psilocybin's durable effects hinting at systemic impacts on aging.Reference Paper:Study: Psilocybin treatment extends cellular lifespan and improves survival of aged miceRelated content:Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Send us a textThe effects of protein restriction on metabolism, liver hormones, brain, and behavior.Episode Summary: Dr. Christopher Morrison talks about how animals sense and prioritize nutrients like protein, discussing defense mechanisms for essentials such as oxygen, water, sodium, and energy; the brain's role in detecting protein deprivation via signals like FGF21; trade-offs between growth, reproduction, and longevity under protein restriction; and reconciling high-protein diets for satiety and muscle maintenance with low-protein benefits for metabolic health and lifespan extension.About the guest: Christopher Morrison, PhD is a professor and researcher at the Pennington Biomedical Research Center in Baton Rouge, Louisiana, where he has worked for over 22 years focusing on nutrition, metabolism, and chronic diseases like obesity and diabetes.Discussion Points:The body prioritizes nutrients hierarchically: oxygen and water first, then sodium, energy, and protein, with weaker defenses for carbs or fats.Animals develop specific appetites for deprived nutrients, like salt or protein, often through post-ingestive learning rather than just taste.Protein restriction (e.g., 5% vs. 20% in diets) increases food intake and energy expenditure in mice to maintain protein levels, even at the cost of extra calories.FGF21, a liver hormone, signals protein deprivation to the brain (via NTS region), driving protein-seeking behavior and metabolic changes; it's essential for low-protein responses.Protein restriction extends lifespan in lab animals by suppressing growth signals like IGF-1 and mTOR, but may impair immunity or wound healing in real-world conditions.High protein aids satiety, weight loss, and muscle building, but overconsumption may shorten lifespan; optimal intake depends on age, activity, and goals (e.g., not for pregnant or elderly).No one-size-fits-all for protein: mild restriction may benefit middle-aged sedentary people for health, while athletes need more; balance avoids excesses.Related content:M&M 106: Diet, Macronutrients, Micronutrients, Taste, Whole vs. Processed Food, Obesity & Weight Loss, Comparative Biology of Feeding Behavior | Stephen Simpson & David Raubenheimer*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

“We are now branding ourselves as the trusted infrastructure supporter of AI,” says Scott Eaton, Sr. Director, Partner Management at Lumen, in a conversation with Doug Green, Publisher of Technology Reseller News, during ScanSource Partner First. Eaton explained that Lumen, built on the combined legacies of CenturyLink, Level 3, Savvis, and Global Crossing, has transitioned from its telco roots into a technology company focused on powering AI with bandwidth and infrastructure services. Through solutions like wave services, DIA services, data centers, and rapid routes, Lumen provides the backbone for enterprises facing high-intensity data demands. At Partner First, the company highlighted its long-standing partnership with Intelisys, now part of ScanSource, where it has operated for over 20 years in an agency model of recurring commissions. Eaton emphasized that Lumen enables resellers to expand beyond equipment sales and deliver complete customer solutions—moving from “mailbox money” to strategic recurring revenue streams. To simplify adoption, Lumen and ScanSource provide partners with API-driven quoting and ordering tools, training, and field engineering support. This ensures that partners can more easily engage in infrastructure sales, which Eaton described as essential for AI-era growth: “From an AI perspective, it's all about the data… and the high bandwidth requirements to support it.” Eaton noted that partners at the show are eager to learn how to get started, educate themselves, and go deeper with customers. He encouraged resellers to leverage both Lumen's resources and ScanSource's support teams to accelerate success. For more information, visit lumen.com.

The divisional rival 49ers rolled into Lumen far from full strength and yet more than earned the victory they walked away with after a hard-fought game. There are plenty of excuses, but the bottom line appears Seattle is still not on San Francisco's level. Link to my YouTube Channel. Live on Wed and Sunday, 5PM PST...https://www.youtube.com/@TheHawksNest12thman?sub_confirmation=1 Use promo code NEST on Sleeper and get 100% match up to $100! https://Sleeper.com/promo/NEST. Terms and conditions apply. #Sleeper Link to my Patreon....https://www.patreon.com/thehawksnest Twitter...@SeahawksNester Twitch...@TheSeahawksNest

Send us a textSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

-- On the Show: -- Democrat Catelin Drey defeats Republican Christopher Prosch in an Iowa Senate special election flipping a Trump district and ending the GOP supermajority -- Donald Trump deploys more than 2,200 National Guard troops from multiple states to collect trash in Washington DC as part of a beautification mission -- The White House pushes back as questions mount over Donald Trump's health after visible bruises, swelling, and cognitive slip-ups -- Trump makes false claims about crime, autism, prescription drugs, and restaurants while Robert F Kennedy Jr rants about radioactive shrimp during a chaotic cabinet meeting -- Cabinet officials and allies, including Tulsi Gabbard, Kristi Noem, Kelly Loeffler, and others, lavish praise on Donald Trump in an extraordinary display of flattery -- Support among young men who backed Trump in 2024 collapses as economic struggles, immigration raids, and broken promises sour his appeal -- California Governor Gavin Newsom publicly raises concerns about Trump's mental fitness -- Trump mocks Gavin Newsom's hand movements while Newsom fires back online -- Trump posts a series of late night Truth Social rants boasting about fundraising, crime, and attacking Seth Meyers -- Charlie Kirk tells Taylor Swift to reject feminism and submit to her fiancé, Travis Kelce, in a bizarre rant about their engagement -- On the Bonus Show: Trump signs an executive order against flag burning, Trump wants to change the Defense Department's name to the Department of War, US threatens to withhold funding from states over truck driver English proficiency rules, and much more...

-- On the Show: -- Donald Trump reverses his ceasefire stance after meeting Vladimir Putin and pressures Volodymyr Zelenskyy to accept land concessions without a ceasefire -- Trump fails to see Finnish President Alexander Stubb sitting directly in front of him and asks where he is during a public event -- Trump blames Barack Obama for losing Crimea and defends Vladimir Putin while dismissing Ukraine's NATO aspirations -- Trump praises Vladimir Putin during a red carpet meeting and blames Ukraine for getting invaded while downplaying Russia's aggression -- Wholesale vegetable prices surge nearly 40 percent in July raising fears of sharp increases in grocery costs for consumers -- Washington DC restaurant reservations plunge more than 25 percent after Donald Trump federalizes the police and militarizes the city -- Gavin Newsom rises in Democratic primary polls for 2028 after his redistricting efforts -- Fox News personalities criticize Gavin Newsom for mocking Trump online exposing hypocrisy about Trump's own years of ridicule -- On the Bonus Show: Texas Democrats monitored by law enforcement after returning to state, Trump vows to end mail-in voting, Ohio's Sherrod Brown launches bid for US Senate, and much more... ⚠️ Ground News: Get 40% OFF their unlimited access Vantage plan at https://ground.news/pakman

This week we are airing another episode of Unconditional featuring the hilarious Ghosts star, Asher Grodman, to talk about his deep bond with his dog, Zazie. From her playful energy to her unwavering companionship, Asher shares how Zazie has been a grounding force in his life, especially during challenging times.   Sponsors: Go to  Lumen.me/pineapple for 15% off your purchase.Cornbread Hemp - Save 30% on your first order by going to ⁠cornbreadhemp.com/pineapple⁠ and use the code “pineapple” at checkout.Quince Cookware: ⁠quince.com/maggie⁠ for free shipping and 365 day returnsQuince Apparel: ⁠quince.com/pineapple⁠ for free shipping and 365 day returns Learn more about your ad choices. Visit megaphone.fm/adchoices

-- On the Show: -- Inflation rose sharply in July under Trump's economy, driven by tariffs causing prices to increase above the Fed's ideal range -- Trump's firing of the Bureau of Labor Statistics head raises questions about the credibility and political influence on inflation and jobs data -- Layoffs in the US surged to the highest level since the COVID pandemic, fueled by federal job cuts, tariffs, AI automation, and private sector downsizing -- Trump's takeover of DC police and deployment of National Guard troops sparked protests and potential resistance from the Guard -- Trump's strange remarks about sidewalk scrubbing during a speech leave his staff bewildered -- Trump's FBI Director Kash Patel publicly contradicted MAGA narratives by reporting record low murder rates, enraging Trump -- Donald Trump confused Alaska with Russia during a speech, exposing incoherence and hypocrisy in right-wing media responses -- Trump's press secretary Karoline Leavitt had a visible meltdown on camera when asked a simple question about the Epstein scandal -- Marjorie Taylor Greene publicly attacks other MAGA figures, exposing internal conflict and power struggles within the movement -- Jeanine Pirro struggled when confronted with real crime data showing declines, undermining the MAGA narrative -- Defense Secretary Pete Hegseth dodged questions about the fate of homeless people after Trump's plans to clear homeless encampments -- On the Bonus Show: Pete Hegseth retweets Christian nationalist pastor, Project 2025 guy picked for BLS leader, MTG accused of sketchy stock trading, and much more...

The Trump EPA radically revises regulations over greenhouse gas emissions, and we're joined by Energy Secretary Chris Wright to discuss the energy revolution; Cory Booker gets performative on the Senate floor; and The New York Times admits a horrifying screw-up in its Gaza coverage. Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2249 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Watch Journey to the UFC: Joe Pyfer now—streaming exclusively on DailyWire+. My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiro Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: Perplexity - Perplexity is an AI-powered answer engine that searches the internet to deliver fast, unbiased, high-quality answers, with sources and in-line citations. Ask Perplexity anything here: https://pplx.ai/benshapiro PureTalk - Switch to PureTalk and start saving today! Visit https://PureTalk.com/SHAPIRO Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen. CovePure - Go to https://covepure.com/shapiro to get $200 off. One Nation America - Learn more at https://OneNationAmerica.org - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53  Follow on Instagram: https://bit.ly/3QtuibJ  Follow on Facebook: https://bit.ly/3TTirqd  Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy Learn more about your ad choices. Visit megaphone.fm/adchoices

The Trump EPA radically revises regulations over greenhouse gas emissions, and we're joined by Energy Secretary Chris Wright to discuss the energy revolution; Cory Booker gets performative on the Senate floor; and The New York Times admits a horrifying screw-up in its Gaza coverage. Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2249 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Watch Journey to the UFC: Joe Pyfer now—streaming exclusively on DailyWire+. My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiro Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: Perplexity - Go to https://helixsleep.com/klavan to get an exclusive discount. PureTalk - Switch to PureTalk and start saving today! Visit https://PureTalk.com/SHAPIRO Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen. CovePure - Go to https://covepure.com/shapiro to get $200 off. One Nation America - Learn more at https://OneNationAmerica.org - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53 Follow on Instagram: https://bit.ly/3QtuibJ Follow on Facebook: https://bit.ly/3TTirqd Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy

Director of National Intelligence Tulsi Gabbard declassifies a House Intelligence Committee report showing the Obama team doctored intel to conclude that Russia wanted Trump in 2016; journalist Michael Tracey joins us to discuss what's actually in the Epstein files; and President Trump brings Columbia University to heel.Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHEEp.2245- - -Facts Don't Care About Your Feelings- - -DailyWire+:Right now you can gift Daily Wire plus for 40% off with code JULY at DailyWire.com/gift (https://www.dailywire.com/gift).My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiroGet your Ben Shapiro merch here: https://bit.ly/3TAu2cw- - -Today's Sponsors:ExpressVPN - Go to https://expressvpn.com/ben and find out how you can get 4 months of ExpressVPN free!Cookunity - Go to https://www.cookunity.com/benfree for Free Premium Meals for Life. Thanks to CookUnity for supporting the show!Policygenius - Head to https://policygenius.com/SHAPIRO to get your free life insurance quotes and see how much you could save.Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen.One Nation America - Learn more at https://OneNationAmerica.org- - -Socials:Follow on Twitter: https://bit.ly/3cXUn53Follow on Instagram: https://bit.ly/3QtuibJFollow on Facebook: https://bit.ly/3TTirqdSubscribe on YouTube: https://bit.ly/3RPyBiB- - -Privacy Policy: https://www.dailywire.com/privacy

Joe Biden's doctor takes the Fifth when asked whether Biden was healthy or not; President Trump's team undercuts him on Ukraine's defense; and the administration targets California for failing to defend girls in sports. Click here to join the member-exclusive portion of my show: https://bit.ly/3WDjgHE Ep.2235 - - - Facts Don't Care About Your Feelings - - - DailyWire+: Join millions of people who still believe in truth, courage, and common sense at https://DailyWirePlus.com. My new book, “Lions and Scavengers,” drops September 2nd—pre-order today at https://dailywire.com/benshapiro Get your Ben Shapiro merch here: https://bit.ly/3TAu2cw - - - Today's Sponsors: ExpressVPN - Go to https://expressvpn.com/ben and find out how you can get 4 months of ExpressVPN free! SimpliSafe - Visit https://SIMPLISAFE.com/SHAPIRO to claim 50% off a new system with a professional monitoring plan and get your first month free. Lumen - Go to https://lumen.me/SHAPIRO to get 10% off your Lumen. IFCJ - To learn more about IFCJ's lifesaving work, visit https://benforthefellowship.org Birch Gold - Text BEN to 989898 for your free information kit.  - - - Socials: Follow on Twitter: https://bit.ly/3cXUn53 Follow on Instagram: https://bit.ly/3QtuibJ Follow on Facebook: https://bit.ly/3TTirqd Subscribe on YouTube: https://bit.ly/3RPyBiB - - - Privacy Policy: https://www.dailywire.com/privacy