Podcasts about FAM

FAM! We are so excited to share episode 1 of our coverage of Mr. and Mrs. Murder with you! ALL 4 EPISODES ARE AVAILABLE RIGHT NOW AND AD FREE ON PATREON! FAM - we're heading down to Florida for this new series, and starting off with a bang in alligator territory.  We meet two couples, Mike and Denise Williams and their friends Kathy and Brian Winchester, whose lives intertwine in ways beyond simple friendship.  When Mike disappears on a duck hunting trip - but seriously, what did those cute little duckies do to you? - suspicions arise that perhaps foul play was involved, and maybe he wasn't just eaten by the alligators. Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!!

"La fam

As festas de fim de ano são um momento aguardado: reencontros com familiares e amigos, mesas fartas e as expectativas para um novo ciclo que se inicia. É uma época de celebração, gratidão e alegria. No entanto, é também um período em que os excessos – seja na alimentação, na bebida ou até mesmo na quebra da rotina – podem se tornar vilões, impactando nossa saúde e bem-estar de forma significativa. Pensando nisso, então, como aproveitar todas as delícias e a magia das confraternizações sem colocar a saúde em risco? No UFOP Entrevista de hoje, conversamos com Pedro Henrique Miranda, docente do Departamento de Medicina de Família, Saúde mental e Coletiva, que apresenta informações muito importantes sobre como conciliar todas essas questões no fim de ano, tendo em vista a alimentação, a hidratação e manutenção de hábitos saudáveis para toda a família. Ficha Técnica:Produção: Maria Caroline Carmo Edição de Texto: Patrícia ConscienteEdição de áudio e sonoplastia: Eduardo Rodrigues

“Pó de Sim, Pó de Não” (2025), é um Original Leiturinha escrito pela paulista Andrea Avelar e ilustrado pelo cearense Felipe Calv. É um dos livros criados especialmente pela Editora Leiturinha, que estimula autonomia, imaginação, empatia e raciocínio, além de fortalecer o vínculo familiar e o prazer da leitura. Hoje conhecemos a Família Ventura, pessoas que conversam sobre sonhos, sentimentos e emoções. “Pó de Sim, Pó de Não” trabalha emoções de maneira lúdica, usando os pós para ajudar as crianças a nomearem sentimentos, elaborarem frustrações e, assim, encontrarem o equilíbrio emocional. São muitas prateleiras e rótulos, assim como a vida, que é totalmente diversificada! Note que nesta história, o menino Benício está totalmente envolvido com as tradições de sua família, isso conversa demais com essa época do ano em que estamos, que é a das festas. A festa da história, é o aniversário do menino, que ao completar 7 anos, recebe a última das chaves para ter acesso à Sala Empoeirada da casa dos Ventura. A história traz em essência dois valores primordiais: 1- os momentos e rituais compartilhados em família; 2- e a celebração dos livros, quando o menino vai escrevendo suas páginas novas, a partir dos sentimentos que descobre e os pós que mistura. Ou seja, o poder da leitura e do amor são celebrados como laços inquebrantáveis! Por isto, este episódio é tão especial para nós! Chegamos ao episódio 300! Concluindo a sexta temporada! Nós temos muito o que celebrar! Sabia que a partir da nossa parceria com o maior clube de assinaturas de livros infantis do Brasil, o frete da sua assinatura pode sair de graça!? São R$ 120 de desconto nas assinaturas anuais, planos UNI ou DUNI. Acesse o Link https://leiturinha.com.br/?utm_source=influenciadores%20&utm_medium=social%20&utm_campaign=LEITURADEOUVIDO_dezembro&pin=LEITURADEOUVIDOe tenha frete grátis garantido com nosso cupom: LEITURADEOUVIDO#momentoleiturinha #leiturinha✅ Torne-se MEMBRO do CLUBE LEITURA de OUVIDO: encontros virtuais mensais, com notas de rodapé ao vivo e interação entre os leitores e Daiana Pasquim. Para isso, faça um apoio a partir de R$ 20 mensais:

Avui valorarem els tallers d'acompanyament a la sexualitat que s'han fet a Lloret de Mar. L'Ajuntament, a través del departament d'Igualtat, ha dut a terme una sèrie de tallers per fer un acompanyament a la sexualitat. La voluntat ha estat oferir una mirada compartida, preventiva i transformadora, tant a infants i joves, com a professionals de l'àmbit social i famílies. En farem les valoracions pertinents amb l'encarregat dels tallers, Xavi Ybeas, i amb la tècnica d'Igualtat de l'Ajuntament de Lloret, Lisi Campos. Altres titulars del dia: L'Ajuntament de Lloret ha inaugurat els nous despatxos de Benestar i Família, que es troben a peu de carrer i que tenen per objectiu facilitar l'accés de la ciutadania als serveis socials del municipi i reforçar la proximitat amb les persones. Ho explicarem i escoltarem el regidor de Benestar i Família, Alejandro Pérez. Una novel·la de la lloretenca Laura García-Martín s'ha convertit en best seller. Es titula Todo es posible en Navidad i avui tindrem el plaer de parlar-ne amb ella. Amb la regidora de Festes, Vereda López, donarem els detalls del parc de Nadal, que obrirà les portes al pavelló municipal del 27 al 30 de desembre. A partir d'avui, es pot visitar a la Casa de la Cultura una exposició sobre l'art contemporani al territori, que recull obres d'artistes gironins seleccionades a la 12a biennal d'art de Girona. Ho explicarem entrevistant el diputat de Cultura de la Diputació de Girona, Jordi Camps. Explicarem, també, que aquest dijous el Cineclub Adler prepara l'última projecció de l'any: “La història de Souleymane”. En parlarem amb el president de l'entitat, Joan Moret. Al BDBH d'avui també entrevistarem a Xavier Albertí, perquè el lloretenc dirigeix ‘La corona d'espines’, l'obra en vers de Josep Maria de Sagarra que es pot veure aquests dies al TNC i que arribarà a Girona el proper mes de març. Per acabar, volem recordar que aquesta tarda es farà una xerrada destinada a donar eines per afrontar les festes de Nadal quan s'està en un procés de dol. Escoltarem la psicooncòloga Rosana Garrigós.

BE STILL OUR LESBIAN HEARTS, FAM!! For our final bonus episode of the year, we're breaking out our Birkenstocks, pausing the canning of vegetables, getting off our Harley Davidsons,  and HOLDING PATRICK VERY TIGHTLY WHILE WE SCREAM FOR THE NEXT HOUR ABOUT THE AMAZING DOCUMENTARY "Lilith Fair: Building A Mystery, The Untold Story." The real true crime here is that it took 25 years for this doc to happen BUT IT WAS SO WORTH THE WAIT! THE PAULACOLESARAHACLAGHLANTRACYCHAPMANBONNIERAITSHERYLCROWERICADADU OF IT ALLLLLLLLLLLL!!! Also, if you haven't checked out our YouTube channel yet GO WATCH THIS ONE! Patrick is literally levitating 4 feet off his chair the entire time. Find and watch "Lilith Fair: Building a Mystery" on Hulu WE'RE ON YOUTUBE - Want to view the episodes and not just listen?  Check our new video feed to see full video episodes starting today. CLICK HERE TO WATCH AND SUBSCRIBE! OUR MERCH STORE IS BACK - AND ON SALE!  Missed out on the merch drops earlier this year?  From now until the end of the year, you can grab all of our remaining stock of merchandise for 30% off!  Shop now!! LOOKING FOR MORE TCO? On our Patreon feed, you'll find over 400 FULL AD-FREE BONUS episodes to BINGE RIGHT NOW, including our episode-by-episode coverage of popular documentary series like Love Has Won: The Cult of Mother God, LulaRich, and The Curious Case of Natalia Grace; classics like The Jinx, Making A Murderer, and The Staircase; and well-known cases like The Menendez Murders, Casey Anthony: American Murder Mystery, and The Disappearance of Madeleine McCann, and so many more! Episode Sponsors: Function - Own your health for $365 a year - a dollar a day!  Visit www.functionhealth.com/TCO or use gift code TCO25 for a $25 credit towards your membership. Everyday Dose - Coffee with benefits! Visit www.everydaydose.com/TCO for  61% off your first subscription order! Quince - Upgrade your closet this year without the upgraded price tag. Go to www.Quince.com/tco for 365-day returns, plus free shipping on your order! Rocket Money - Cancel your unwanted subscriptions and reach your financial goals faster with Rocket Money. Go to www.RocketMoney.com/obsessed today. Home Chef -  Make cooking simple: fresh food delivered, easy recipes to follow and meals that actually taste great. Go to www.HomeChef.com/TCO for 50% off your first box and free dessert for life! Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!!

Nesta edição de CBN e a Família, a comentarista Adriana Müller traz como destaque a importância das mudanças em nossas vidas. Qual conquista desse ano você sente orgulho de ter alcançado? Dentro da sua proposta de mudança de vida, aprendizado de algo, impacto positivo? Ouça a conversa completa!

Família, restaurando a essência do lar - Pr. Marcelo Mathias by Igreja Missionária Evangélica Maranata Para conhecer mais sobre a Maranata: Instagram: https://www.instagram.com/imemaranata/Facebook: https://www.facebook.com/imemaranataSite: https://www.igrejamaranata.com.br/Canal do youtube: https://www.youtube.com/channel/UCa1jcJx-DIDqu_gknjlWOrQDeus te abençoe

FAM - one of our favorites returns!  Cecilie from "Tinder Swindler" is back (surely fresh from Pernilla's yacht), and now she's on a mission to help other women who have fallen prey to dirtbags scamming them with fake romance.  She teams up with private investigator Brianne to help Jill take down the jerk who took her for thousands and thousands of dollars. Find and watch "Love Con Revenge: Selfie Scammer" on Netflix WE'RE ON YOUTUBE - Want to view the episodes and not just listen?  Check our new video feed to see full video episodes starting today. CLICK HERE TO WATCH AND SUBSCRIBE! OUR MERCH STORE IS BACK - AND ON SALE!  Missed out on the merch drops earlier this year?  From now until the end of the year, you can grab all of our remaining stock of merchandise for 30% off!  Shop now!! LOOKING FOR MORE TCO? On our Patreon feed, you'll find over 400 FULL AD-FREE BONUS episodes to BINGE RIGHT NOW, including our episode-by-episode coverage of popular documentary series like Love Has Won: The Cult of Mother God, LulaRich, and The Curious Case of Natalia Grace; classics like The Jinx, Making A Murderer, and The Staircase; and well-known cases like The Menendez Murders, Casey Anthony: American Murder Mystery, and The Disappearance of Madeleine McCann, and so many more! Episode Sponsors: ButcherBox - ButcherBox delivers over 100 premium protein choices straight to your door! Go to www.ButcherBox.com/tco to get free steak in every box for a year  PLUS $20 off your first box!  Dose - Wellness shots formulated by scientists, made for your liver. Save 35% on your first month of subscription by going to www.dosedaily.co/TCO or entering TCO at checkout. MicroPerfumes - Sample luxury fragrances in pocket-sized vials - the high-end experience on your terms! Get up to 60% off at www.MicroPerfumes.com/TCO Hers - Whether you want to lose weight, grow thicker, fuller hair, or find relief for anxiety, Hers has you covered. Visit www.forhers.com/TCO to get a personalized, affordable plan that gets you. Earnin - Get access to your pay as you work. Download the Earnin app in the Google Play or Apple app store. Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!!

JOIN THE FIBER FIX for 2026! We'll be making fiber art postcards together all year long! It's a chance to stretch your skills—one small, joyful project at a time with 12 fiber art challenges, monthly LIVES with Brandy & Mel and a community you will love. Be in the room LIVE WITH US once a month! $85USD/$120CAD/year.TODAY'S PODCAST is all about our new adventure for 2026! I've joined forces with my good friend Mel Beach for a monthly creative punch!Grow, connect, and get that monthly spark of inspiration in the Padlet community with Brandy Maslowski & Mel Beach! NOW OPEN - Kickoff Party (Dec.30th) First Midnight Prompt (Jan.1st) Plus we'll have a BONUS PenPal finale in December! We'd love to have you join the FAM! Quilter on Fire Website - https://quilteronfire.com/OLISO IRONS - Host of the Quilter on Fire Podcast Lounge each year at QuiltCon!BUY YOUR OWN OLISO MINI PROJECT IRON RIGHT HERESquare One Textile Art WorkshopJoin Brandy's email listFree Quilter on Fire Holiday Table Runner VIDEOSUPPORT THE PODCAST by becoming a Quilter on Fire Podcast Angel for as little as $3 per week.Support the showThank you for listening to the Quilter on Fire Podcast.

O Plano Nacional de Cuidados tem como foco quem cuida e é cuidado, em especial mulheres e trabalhadores e trabalhadoras remunerados ou não. O governo federal prevê R$24,9 bilhões para investimentos na área até 2027.Sonoras:

Avui al Voltant i Girant: - A la primera part del Voltant i Girant parlem amb Meritxell Faiges, primera tinent d’alcalde de l’Ampolla, sobre el pressupost de 2026 que recentment s’ha aprovat. - A la segona part del programa ens acompanya Bea González, directora de El Cau, centre d’acompanyament d’Infanto-Juvenil, Família i Adults, de Deltebre, perquè ens expliqui tot sobre el centre.

A la segona part del programa ens acompanya Bea González, directora de El Cau, centre d’acompanyament d’Infanto-Juvenil, Família i Adults, de Deltebre, perquè ens expliqui tot sobre el centre.

#574- Mensagem Culto da Família - Pr. Gustavo Andrade 14/12/2025 by CCZSBH

(00:00-26:30) Is this Ne-Yo or Nay-Yo? Doug, this is a sex show. Grandpa Rivers nearly pulled off the upset against Haenchen's Colts yesterday. Audio of Rivers giving his thoughts postgame. Brady Cook got his first career start and threw his first TD pass yesterday in Jacksonville. Loofahs strictly for the bin. Doug uses bar soap. Hey fellas, how do you bathe? Loofahs on cruises. How did this come up? Don't submit to the shield.(26:38-38:54) I think this might be the jam. Jackson didn't go to many mixers. This guy does a great Margot Robbie impression. Punk move, Papers. Cab sav with a straw. How bad can a stink bug really smell? A smell unlike any other. No Polar Express for Tim & Fam. Audio of Josh Schertz talking about the win over the Dons.(39:04-48:50) Hey look, it's James Carlton. Chairman trying to recruit James to go to Norman this weekend. Not all clients get a gift, but Tim does. Wine and apple pie. Egg nog syrup. The proper Arnold Palmer ratio. CFP matchups for this weekend.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

No Café PT desta segunda-feira, Quenes Payayá, coordenadora do Setorial Nacional de Assuntos Indígenas do PT e consultora da Secretaria Nacional de Cuidado e Família do MDS, analisou a aprovação do Marco Temporal no Senado, uma decisão que contraria o STF e ameaça direitos constitucionais dos povos indígenas.

L'Ajuntament de Lloret ha inaugurat els nous despatxos de Benestar i Família, que es troben a peu de carrer i que tenen per objectiu facilitar l'accés de la ciutadania als serveis socials del municipi i reforçar la proximitat amb les persones. En total, són tres despatxos, que estan ubicats a la plaça Pere Torrent, al lateral de la Casa de la Cultura. Al mateix temps, l'Ajuntament també ha posat en funcionament el nou servei OAC 360º Social. Es tracta d'una nova eina que permetrà resoldre tràmits de manera més ràpida i eficient i agilitzar les consultes i les gestions administratives relacionades amb l'àmbit local. El telèfon és el 872 22 46 00 i també es disposa del correu electrònic oac360social@lloret.cat. Ho ha explicat el regidor de Benestar i Família, Alejandro Pérez, que destaca que és una eina que marcarà una nova etapa en el departament. “Presentem les noves oficines, per donar un servei més proper i amable, i l'OAC 360, per millorar i agilitzar els tràmits i que marcarà una nova etapa en el departament de Benestar i Família”Alejandro Pérez L'acte d'inauguració dels despatxos i la posada en funcionament del servei OAC 360º, també ha comptat amb la presentació de la nova gerent de l'àrea dels Serveis a les persones, Concepció Basté. El regidor ha explicat que se suma aquesta nova professional per aportar més estructura i eficiència al departament. “La nova gerent de l'àrea dels Serveis a les persones té molta experiència en l'administració pública i aportarà estructura i eficiència, per millorar encara més el nostre departament”Alejandro Pérez Totes aquestes iniciatives s'emmarquen dins del projecte Lloret al teu costat, que té per objectiu millorar l'acompanyament ciutadà i fer que les gestions municipals siguin més properes i resolutives.

Andressa Kuhn, médica de Família e Comunidade, falou no Direto ao Ponto sobre a palestra que vai abordar os sinais de alerta de demência e papel da família no cuidado.

Andressa Kuhn, médica de Família e Comunidade, falou no Direto ao Ponto sobre a palestra que vai abordar os sinais de alerta de demência e papel da família no cuidado.

Nesta edição do "Questões de Família", o comentarista José Eduardo Coelho Dias traz como destaque um novo dado envolvendo as relações familiares no Brasil: a guarda compartilhada é o tipo mais comum determinado nos divórcios judiciais no Brasil em 2024, segundo o relatório Estatísticas do Registro Civil, do IBGE (Instituto Brasileiro de Geografia e Estatística). Assim, pela 1ª vez, os divórcios com guarda compartilhada dos filhos (45%) superaram os casos em que a responsabilidade ficou exclusivamente com a mãe (43%).

Again, we get a bit chatty here, why wouldn't we, its Rum! Coming in around 45mins we can hopefully keep your interest and enthusiasm high. As we drift our way through the exotic world of rum cocktails. Pina Colada Joe! We didn't do Pina Colada! Oh well, we did do the Daiquiri so just do a pineapple one of those and add coconut! Beware the Mojito though, delicious but surprisingly tricky. No worries, Joe on hand to guide us through the perfect method. Meanwhile I get my Pimms numbers 1 and 3 muddled. Throw in a bit of US presidential history, ice cream, dishwashers with a dash of brandy and you pretty much have a delicious episode. Big up Fam! Hosted on Acast. See acast.com/privacy for more information.

Felipe Mesquita, Evandro de Freitas e Bruno Carvalho batem um papo sobre as tardes da TV brasileira nos anos 80, 90 e 2000. Esse era o horário em que a televisão se tornava companhia fixa depois da escola, misturando desenhos animados, séries, novelas, programas infantis e atrações populares que ajudaram a moldar uma geração inteira. Nos anos 90, a televisão aberta vivia um momento de enorme força criativa e audiência. Enquanto as manhãs focavam nas crianças, as tardes tinham como foco os jovens. A Sessão da Tarde da Globo e o Cinema em Casa do SBT disputam a atenção dos jovens cinéfilos. A TV Manchete enchia sua programação com animes ("Cavaleiros do Zodíaco") e tokusatsus ("Jaspion" e "Jiraiya"). Junto com isso tinham as reprises de novelas novelas brasileiras no "Vale a Pena Ver de Novo", as novelas mexicanas ("Mario do Bairro" e "A Usurpadora"), programas de fofoca (Sônia Abrão), programas de treta de família ("Casos de Família"), Programa Livre, "Malhação" e muito mais.As tardes da TV brasileira de antigamente representam um período em que a televisão tinha papel central na rotina das famílias. Era um consumo coletivo, sem streaming, sem escolha sob demanda, mas com um sentimento de evento diário. Tudo acontecia ao mesmo tempo para todo mundo.Essa é mais uma edição da nossa série Na TV!==###==- NORDVPN | Tenha uma conexão segura e acesso conteúdos do mundo inteiro! https://nordvpn.com/99vidas- ALURA | Toma aí 20% de desconto na sua assinatura anual! Quer assinar por 2 anos? O desconto é de 40%!!! ! É grande oportunidade para transformar a sua carreira tech!! https://alura.com.br/99vidas

"I'll go back to the backpack analogy. When your kids come home with a backpack, all of a sudden their homework is not on the desk where it's supposed to be. It's in the kitchen; it kind of spreads all over the place, but it's still in the house. When we give antibody–drug conjugates (ADCs), the chemotherapy does go in, but then it can kind of permeate out of the cell membrane and something right next to it—another cancer cell that might not look exactly like the cancer cell that the chemotherapy was delivered into—is affected and the chemotherapy goes over to that cancer cell and kills it," ONS member Marisha Pasteris, OCN®, office practice nurse in the breast medicine service at Memorial Sloan Kettering Cancer Center in New York, NY, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about ADCs in metastatic breast cancer. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  This podcast is sponsored by Gilead and is not eligible for NCPD contact hours. ONS is solely responsible for the criteria, objectives, content, quality, and scientific integrity of its programs and publications.  Episode Notes  This episode is not eligible for NCPD. ONS Podcast™ episodes: Episode 391: Pharmacology 101: Antibody–Drug Conjugates Episode 378: Considerations for Adolescent and Young Adult Patients With Metastatic Breast Cancer Episode 368: Best Practices for Challenging Patient Conversations in Metastatic Breast Cancer Episode 350: Breast Cancer Treatment Considerations for Nurses Episode 303: Cancer Symptom Management Basics: Ocular Toxicities ONS Voice articles: An Oncology Nurse's Guide to Cancer-Related Ocular Toxicities Black Patients With Metastatic Breast Cancer Are Less Informed About Their Clinical Trial Options Communication Case Study: Talking to Patients About Progressive Metastatic Breast Cancer What Is HER2-Low Breast Cancer? ONS Voice drug reference sheets: Belantamab mafodotin-blmf Datopotamab deruxtecan-dlnk Enfortumab vedotin-ejfv Fam-trastuzumab deruxtecan-nxki ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) Guide to Breast Care for Oncology Nurses Guide to Cancer Immunotherapy (second edition) ONS courses: ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ ONS/ONCC® Chemotherapy Immunotherapy Certificate™ Clinical Journal of Oncology Nursing article: Antibody–Drug Conjugates and Ocular Toxicity: Nursing, Patient, and Organizational Implications for Care The Association Between Hormone Receptor Status and End-of-Life Care Among Patients With Metastatic Breast Cancer Oncology Nursing Forum article: Impact of Race and Area Deprivation on Triple-Negative Metastatic Breast Cancer Outcomes ONS huddle cards: Altered Body Image Huddle Card Chemotherapy Huddle Card Targeted Therapy Huddle Card Foundations of Antibody–Drug Conjugate Use in Metastatic Breast Cancer: A Case Study ONS Biomarker Database (refine by breast cancer) ONS Breast Cancer Learning Library American Society of Clinical Oncology (ASCO) homepage Drugs@FDA package inserts National Comprehensive Cancer Network homepage Susan G. Komen metastatic breast cancer page To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "What an ADC is doing is taking the antibody and linking it to a cytotoxic chemotherapy with the idea of delivering it directly into the cell. How I explain this to new nurses or patients is a backpack analogy. If we think of it as a HER2 molecule wearing a chemo backpack, it's going to find the HER2 receptor attached to it and then drop the chemotherapy into the cell via the backpack. Similar to how we come home from work, we open the key to our door, we're carrying all of our items, and then we drop our own personal items in our house." TS 2:30 "The reason that so many patients with metastatic breast cancer are able to receive ADC therapy is because they are targeting two very common antibodies that we see in breast cancer. One is HER2 and the other is trophoblast cell surface antigen 2 (TROP2). These are seen across the board. We see these on triple-negative breast cancers, hormone receptor–positive cancers, and HER2-positive breast cancers. And now we have a new way to talk about HER2, which is a HER2-low. ... Recently, we have found that patients who express low levels of HER2 are able to receive ADC therapy, specifically fam-trastuzumab deruxtecan." TS 4:21 "Another [ADC] that has just been approved is datopotamab deruxtecan. This is another ADC that targets the TROP2 receptor on a cancer cell. This one carries a lot of side effects. I mentioned earlier that you need an ophthalmology clearance because there is a lot of ocular toxicity around this one. We see a lot of blepharitis, conjunctivitis, there can be blurred vision. Another thing we monitor on this one is mucositis. In the package insert, there's a recommendation for using ice chips while receiving the treatment. ... Then in the HER2-positive and HER2-low space is the big one, which is fam-trastuzumab deruxtecan. This was approved in 2019 for the HER2-positive patients, then more recently in the HER2-low [patients]. The big [side effect] with this one is interstitial lung disease." TS 10:11 "Interstitial lung disease is an inflammation or a little bit of fibrosis within the lung that causes an impaired exchange between the oxygen and carbon dioxide. This was seen in the clinical trials, specifically around fam-trastuzumab deruxtecan. During the trials, they had a very small percentage, I think it was 1%, that died due to interstitial lung disease. So, this is a very important side effect for us as nurses to be aware of. It typically presents in patients like a dyspnea. A lot of times, it's like, 'Well, I used to be able to walk my kid to the bus stop, but now when I walk there, I feel really short of breath.' Or 'I've had this dry cough for the past couple weeks and I've tried medications, but haven't had that relieved.' So, we really need to be aware of that because early intervention in interstitial lung disease is key." TS 12:57 "ADCs are toxic drugs. They have the benefit of being targeted, but we know that they carry a lot of side effects. ... Their specificity makes them so wonderful and we've seen amazing responses to these drugs. But also, we want patients to be safe. We want to give these drugs safely. So, we have to assess our patients and make sure that this is an appropriate patient to give this therapy to. I think that's an open conversation that clinicians need to have with patients regarding these drugs." TS 18:08

Por que tantas pessoas se encantam por líderes autoritários? O psicanalista e tradutor Paulo Schiller, autor do ensaio A Paixão Pela Mentira: a Família e as Tiranias (Todavia), discute neste episódio as origens do fascínio por tiranos. A partir do seu trabalho na psicanálise, Schiller diz que a ascensão do totalitarismo no século passado e seus ecos do mundo de hoje têm raízes nas relações familiares e nos silêncios a que nos acostumamos desde a infância. Na conversa, ele ainda fala sobre a experiência de traduzir o escritor húngaro László Krasznahorkai, vencedor do Prêmio Nobel de Literatura de 2025, que também explora o poder da mentira no seu romance Sátántangó (Companhia das Letras). Apoio: Lei Rouanet - Incentivo a Projetos Culturais. Assine a Quatro Cinco Um por R$ 10/mês: https://bit.ly/Assine451  Seja um Ouvinte Entusiasta e apoie o 451 MHz: https://bit.ly/Assine451  

In April 2005, Ha Smith, a prominent Vietnamese-American fortune teller, and her adult daughter, Anita Vo, were found brutally murdered in Smith's home. They had been beaten and stabbed. The killer had stolen cash, jewelry, and credit cards, and poured white paint over the victims' heads and hands, a detail that initially led police to consider that it had been a ritualistic killing. It would take weeks and a cross country manhunt to uncover the truth. Fam, THIS. ONE. IS. WILD. Find and watch "In Ice Cold Blood: Miss Fortune" on Peacock WE'RE ON YOUTUBE - Want to view the episodes and not just listen?  Check our new video feed to see full video episodes starting today. CLICK HERE TO WATCH AND SUBSCRIBE! OUR MERCH STORE IS BACK - AND ON SALE!  Missed out on the merch drops earlier this year?  From now until the end of the year, you can grab all of our remaining stock of merchandise for 30% off!  Shop now!! LOOKING FOR MORE TCO? On our Patreon feed, you'll find over 400 FULL AD-FREE BONUS episodes to BINGE RIGHT NOW, including our episode-by-episode coverage of popular documentary series like Love Has Won: The Cult of Mother God, LulaRich, and The Curious Case of Natalia Grace; classics like The Jinx, Making A Murderer, and The Staircase; and well-known cases like The Menendez Murders, Casey Anthony: American Murder Mystery, and The Disappearance of Madeleine McCann, and so many more! Episode Sponsors: Function - Own your health for $365 a year - a dollar a day!  Visit www.functionhealth.com/TCO or use gift code TCO25 for a $25 credit towards your membership. Chewy - Every pet deserves a wish come true. Send your pet's wish to www.Chewy.com/ChewyClaus and it might become a reality. Plus, your wish means Chewy will donate five meals to pets in need. Zbiotics - Try PreAlcohol before drinking and wake up feeling great the next day. Head to www.ZBiotics.com/TCO and use the code TCO at checkout for 15% off. DripDrop - Doctor-developed hydration that works faster than water alone. Use promo code TCO at www.dripdrop.com for 20% off your first order! Ritual - Ritual's Essential for Women 18+ is a multivitamin you can actually trust. Get 25% off your first month at www.Ritual.com/TCO Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!!

*No International Laws were broken during the recording of this episode.*Dr. Mijal Bitton is a spiritual leader at the Downtown Minyan, an NYU sociologist, a scholar-in-residence at the Maimonides Fund, co-host of the Wondering Jew podcast AND she's right here on Substack at Committed by Mijal Bitton . We discuss being a sephardic, south American Jew, orthodox feminism, dirty words in the bible, and even some TV recommendations (Pluribus anyone??)Good for the Jews is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.Also ICYMI, Van Jones had a dream come true this week….I don't want to embarass the happy couple even more, but let me just say that AI is a wonderful tool and you can do many fun things with it and share here, if you are inclined.To end on an even more positive note, last week over a thousands Jews and friends stood outside the Park East Synagogue in the freezing cold to show their support after the congregation was attacked by a bunch of losers in Keffiyah's and masks. A Holocaust survivor Rabbi told us not to be afraid. Matisyahu sang songs about peace. An adorable kids choir sang their hearts out. Every single speaker talked about their love of NYC, America, and thanked the NYPD to the cheers of the crowd. Fam, you're in good company. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit askajew.substack.com/subscribe

No Papo Antagonista desta quarta-feira, 10, Madeleine Lacsko e Duda Teixeira entrevistaram Luiz Kignel, advogado especializado em Direito de Família e Sucessões, que falou sobre o universo das sugar babies e daddies. O assunto ganhou destaque após o UOL publicar que Daniel Vorcaro, dono do Banco Master, doou um apartamento de R$ 4,3 milhões para uma sugar baby.Papo Antagonista é o programa que explica e debate os principais acontecimentos do   dia com análises críticas e aprofundadas sobre a política brasileira e seus bastidores.     Apresentado por Madeleine Lacsko, o programa traz contexto e opinião sobre os temas mais quentes da atualidade.     Com foco em jornalismo, eleições e debate, é um espaço essencial para quem busca informação de qualidade.     Ao vivo de segunda a sexta-feira às 18h.    Apoie o jornalismo Vigilante: 10% de desconto para audiência do Papo Antagonista  https://bit.ly/papoantagonista  Siga O Antagonista no X:  https://x.com/o_antagonista   Acompanhe O Antagonista no canal do WhatsApp. Boletins diários, conteúdos exclusivos em vídeo e muito mais.  https://whatsapp.com/channel/0029Va2SurQHLHQbI5yJN344  Leia mais em www.oantagonista.com.br | www.crusoe.com.br 

Home Office oder zurück ins Büro - wo sind wir eigentlich wirklich produktiv? Dazu gibt's eine berührende FAM über Weihnachtsrituale und ein DADA über einen Wandel, den niemand hat kommen sehen ✨ Anschließend wird's richtig deep: Eine Hörerin erlebt emotionalen Betrug nach nur vier Monaten und fragt sich, ob man nochmal neu anfangen kann, oder ob man sich damit am Ende selbst verliert ❤️ Wir sprechen über Grenzen, Vertrauen und warum Kontrolle keine echte Sicherheit schafft. Viel Spaß! (mehr Informationen zu unseren Werbepartnern und die entsprechenden Links zum Einlösen der Rabatte findet ihr unter https://linktr.ee/zweidreissiger.partner - auch dabei viel Spaß)Tickets für unsere Tour gibt es auf: https://contracreate.com/profil/zwei-dreissiger/Folgt dem Podcast auf Spotify und hinterlasst gerne eine Bewertung. Feedback und Werbeanfragen an: hey@zweidreissiger.deUnser Merchandise: https://zweidreissiger.de/ Unser Kaffee: https://flowersandmels.de/ Zu Melisa: https://Instagram.com/findingmelisa/ Zu Flo: https://Instagram.com/floriangerl/Zum Podcast: https://www.instagram.com/zweidreissiger/ Hosted on Acast. See acast.com/privacy for more information.

Confira na edição do Jornal da Record desta terça (9): Deputado Glauber Braga é retirado à força após ocupar cadeira da presidência da Câmara dos Deputados. Confusão tem empurra-empurra e jornalistas agredidos. Votação do projeto que pode reduzir pena de Bolsonaro, deve acontecer ainda nesta terça-feira (9). Motorista sem pontos na carteira terá a CNH renovada automaticamente. Família de traficante do Rio de Janeiro é detida com joias em rodovia que faz fronteira com a Bolívia. Ministro da Justiça diz que estados não fazem nada para combater a criminalidade. Ciclone provoca mortes e estragos no Sul do país. Em Santa Catarina, família enfrenta a enchente e carro é levado pela correnteza. Austrália proíbe menores de 16 anos de terem contas em redes sociais. 

Click here to send me a quick message :) It is a total MYTH that nursing is birth control, so if you've heard that I'm sorry to say, you're out of luck. It is true that for some people, lactation may deter ovulation for many months or years. But it is NOT true for everyone, unfortunately.This is why there are so many unexpected pregnancies that come soon after a previous one. And honestly, unless you are planning on that, it can be pretty shocking and a lot to navigate a new pregnancy with a nursing babe and still healing postpartum.One of the most confusing times to track our cycles, especially if we're practicing FAM for contraception, is postpartum. A few weeks ago, I received a question about this on Instagram, so I figured, why not answer it here so everyone can benefit.So many folks would prefer to prevent pregnancy in this time if possible.But between the sleep disturbances, stress, depletion, body healing, and hormones adjusting of the postpartum time, cycles can be WONKY.And you won't bleed before you ovulate, so you can't rely on that to tell if you're fertile either...So what CAN you do? What's important to consider? What's reliable and what's not?I go into all my thoughts on this, pretty Q+A free-flow style today. I hope it feels like a helpful resource for you, now or in the future when you need it. Resouces:Get on the waitlist for a special offer: Natural Contraception Winter 2026 waitlistGrab the free guide: Track Your Cycle using FAMToday's shownotes: Cycle tracking postpartum?Episode 90: 5 effective non hormonal birth control optionsIf you loved this episode, share it with a friend, or take a screenshot and share on social media and tag me @herbalwombwisdomAnd if you love this podcast, leave a rating & write a review! It's really helpful to get the show to more amazing humans like you.  ❤️DISCLAIMER: This podcast is for educational purposes only, I am not providing any medical advice, I am not a medical practitioner, I'm an herbalist and in the US, there is no path to licensure for herbalists, so my role is as an herbal educator. Please do your own research and consult your healthcare provider for any personal concerns.Support the show

視聴者の皆さんが一番苦手とする英語、それはズバリ「日常英語」ではないでしょうか？ビジネス英語やプレゼン英語は型が決まっていますが、日常会話は使う単語は中学レベルなのに、テンポが速く、音が変化し、意味がつかみにくい…。実はここが一番の難関です。今回は、これからの季節にぴったりな映画『ホーム・アローン』の名シーンを使って、中学英語レベルのシンプルな会話を「ネイティブの音」で話すための発音トレーニングを行います。喉奥発声まずは英語の発声練習で軽くWarm upしましょう！英語の発音に重要なのは「喉の響き」と「息の流れ」です。英語は「喉奥」から声を出すことで、英語らしい太い響きが得られ、特に母音が豊かに響く様になり、言葉が相手に伝わりやすくなる。1.欠伸をして喉奥を広げる2.ソフトパレットに息を当てる3.喉をリラックスさせて声を出す① hah~hah~hah~high(x3) | It's higher than I thought.② mah~mah~mah mom(x3) | Your mom looks so sweet.③ ha~ha~ha~hand(x3) | Add a handful of pepper.                                                            ④ ma~ma~ma~man(x3) | His dad is a handsome man.⑤ sah~sah~sah~salt(x3) | Sprinkle some salt on it.　息の流れを止めずに発音することで、意味ごとのかたまりで発音できる様になる。また発音に息が絡むことで子音の輪郭がはっきりし伝わりやすくなる。またリズムは「長短」を繰り返す感じで、意味の強い言葉が長く発音される様にしましょう。① Sah sa  (x3) “silent” (×3) | You should keep silent.② Fa fa (x3) “family” (×3) | That's one of our biggest family events.③ Thah tha (x3) “thoughtful” (×3) | What a thoughtful decision you made.④ Ta ta (x3) “Tangle” (x3) | Let's take a look at the tangle.⑤ Ka ka (x3) “casted” (x3) | Casting games for tuna is very popular.ゆっくりから徐々にテンポを上げていきます。必ず一息で繋げて発音できる様にしましょうMerry Christmas./Me ri Kris mus/「メリークリスマス」May I sit down?/Meai Si(t) Daun?/「座ってもいい？」That's my granddaughter up there,/thats mai Grand Dah der up Their/「あそこにいるのが私の孫だよ」the little red-haired girl. /thuh Li do Re(d) Heir(d) Gerl/「小さい赤毛の女の子さ」She's about your age. /Shee za Bau chur Eij/「君と同じくらいだね」Do you know her?/Dyoo Nou (h)er?/「彼女のこと知ってる？」You live next to me, don't you?/yu liv Neks(t) mi Doun chu/「君、私の隣に住んでるだろ？」You can say hello when you see me. /Yoo kan Sei he Lou wen-yu See mee/「私に会ったら、挨拶してくれていいんだよ。」You don't have to be afraid./Yoo doun Hav tu Bi a Freid/「怖がらなくて大丈夫だ。」There's a lot of things going around about me, /Theirz-a Lah duv Things Gou-ing-a Raund-a Bau(t) mee/「色々と噂になってるけど」but none of it's true. Okay?/bu(t) Nun-uv-its Troo, o Kei?/「全部嘘だ」You been a good boy this year?/yu Been-a Goo(d) Boi this Yeer/「今年は良い子にしてた？」I think so./ai Think sou/「たぶん」Swear to it?/Sweir-tu It/「誓えるかい？」No./Nou/「いいや」Yeah, I had a feeling./Yea, Ai had-a Feel-ing/「そんな気がしてたよ。」Well, this is the place to be if you're feeling bad about yourself./wel This iz tha Pleis tu bi,if-yur Feel-ing Bad-a Baut yur Self/「自分のこと嫌になってるなら、 ここに来るのが一番だよ。」It is?/i  diz?/「そうなの？」I think so./ai Think sou/「そうだよ」Are you feeling bad about yourself?/Ar yoo Feel-ing Bad-a Baut-yur Self?/「自分のこと、嫌になってるの？」No./Nou/「いいや」I'm in kind of a pain lately./Aim-in Kain-uv-a Pein Lei(t) li/「最近ちょっとつらいんだ」I said some things I shouldn't have. /ai Sed sum Things-ai Shoodn Hav/「言っちゃいけないことを言ってしまってね。」I really haven't been too good this year. /ai Reeh li havn Been too Good this Yeer/「今年は正直、あまり良い子じゃなかった。」I'm kind of upset about it…/um Kain-uv up Set-a Baut-it/「そのことで、ちょっと気が滅入ってて…」Because I really like my family. /bi Kahz ai Reeh li Laik mai Fam li/「家族のことは大好きなんだ」Even though sometimes I say I don't. /Ee vun Thou Sum Taims-ai Sei-ai Doun(t)/「ときどき嫌いって言っちゃうけど」Sometimes I even think I don't. /Sum Tains-ai Ee vun Think-ai Doun(t)/「ときどきいなくなればいいなんて思っちゃうこともあるけど」Do you get that?/Doo-yu Ge(t) Tha(t)?/「分かる？」I think so./ai Think sou/「分かるよ」では、セリフを完全に真似てみましょう。・同じトーン、リズムで発音・意味を想像しながら発音・文字離れ出来るまで反復・言葉に詰まらなくなるまで反復ブレスフローとリズムホームアローンで発音練習コピーイング

Quando Bacellar será solto? Veja os próximos passos após Alerj aprovar revogação da prisão. DF tem sete foragidos na lista de mais procurados do Ministério da Justiça; saiba quem são. Família de traficante Peixão é detida pela PRF tentando fugir do país com fortuna em joias; mulher e filhos seguiam para a Bolívia. Ciclone deve passar pelo RS causando temporais, granizo e ventos de 100 km/h; 'perigo extremo', diz Climatempo. 13º salário: segunda parcela do pagamento cai um dia antes em 2025; saiba motivo e calcule valores.

Governo lança aplicativo com aulas gratuitas para CNH e oficializa novas regras nesta terça. STF começa julgamento dos seis réus do núcleo 2 da trama golpista. Família é alvo de ataque a tiros na Zona Oeste do RJ. Evento em colégio cívico-militar do Paraná faz exposição de fuzis para estudantes. Ciclone extratropical traz temporais para o Centro-Sul.

This week we are joined by fellow Outlander Travel agent Meg, who recently traveled to Cancún on an exclusive FAM trip, touring multiple resorts across the stunning Cancún area to bring back firsthand insights and insider tips. Tune in as Meg shares her experiences, from breathtaking beaches to top-notch accommodations, helping you plan your next […]

Catch Up on what the Sister Wives family has been up to this week! Be sure to tune into our weekly watch-alongs of the most recent episodes of Season 20 & our regular Weekly Hot Topics on your favorite podcast app and Youtube.SHOW LINEUP:-TLC SW Apology Tour graphic-Bryannah's TikTok about K&R's movers and dolls-Christine & Fam gear up for Xmas (and kind of shades Meri with her own BOBS)-Tony and Mykelti: USLESS!-Meri's best shirt in SW history-Meri: What IS Worthy Up?-Leon & Audj cash in and we are living!-Salty Tension-Queen Janelle continues to Janelle-Christine's Book Chapters 24-26LEAVE US A VOICEMAIL AND SHARE YOUR THOUGHTS!https://www.speakpipe.com/msg/s/384445/1/grbop5liib63rf2tSnark and sarcasm is highly encouraged as we see what our favorite family is up to, as well as a dip into the latest pop culture news and highlights. Subscribe on YouTube, Patreon, and your favorite podcast app!Please like and subscribe on Youtube!Join our private Facebook Group "We Love to Hate Everything"Coming up this week on Patreon:patreon.com/lovetohatetv + patreon.com/trpod*THE ENTIRE BACKLOG OF AMANDA LOVES TO HATE TEEN MOM IS AVAILABLE FOR only $3*WE LOVE TO HATE TV*Tier 1+: Jon & Kate Plus 8 S3 E9 "Gosselin Family Christmas"*Tiers 2+: Sister Wives S15 E1 "Being Strong or Being a Bitch"TOTAL REQUEST PODCASTJon & Kate Plus 8 S3 E9 "Gosselin Family Christmas"GIRL DINNERGirl Dinner Episode 69 "Our Favorite Things 2025"CHECK OUT AMANDA'S OTHER PODCAST POD AND THE CITY!!! Available on Itunes/Spotify etc, Youtube, and Patreon! Hosted on Acast. See acast.com/privacy for more information.

Um novo estudo da FGV mostra que o Programa Bolsa Família, além de aliviar os efeitos imediatos da pobreza, contribuiu para a independência de 60,68% dos beneficiários em 10 anos. No recorte entre 15 e 17 anos, 71% desses “Filhos do Bolsa Família” não dependem mais desse apoio financeiro. Sonoras:

In this episode of For The Dads with Former NFL Linebacker Will Compton, hosts Will and Sherm talk a recap of their thanksgiving with the Fam and Friends, check in on the Compton Household Flu, and break down have arguably our most hilarious call-in to date — all while keeping the episode fun, light and of course, under an hour. The episode kicks off with Will & Sherm discussing how Will’s Daughter called him “Will” before they dive into some hilarious conversations, including: Making up the word Falconia as a medical disease (Shoutout Sherm) Of Course, Olipop and Terminal List Chef talks Turkey Other highlights include: An ELITE Dad Hack for Kid Photos Will Compton's Reading His First Fiction Novel!

Is artificial intelligence the best thing that ever happened to small tourism companies? Dan Flores believes it may be. A longtime travel marketing executive and current head of tourism for Satisfi Labs, Dan has worked with dozens of organizations to help leverage the power of AI to extend their capabilities and increase sales. And he's excited about what the future this technology holds for tourism entrepreneurs. Dan joins this episode of the podcast to share how AI can give small tour companies a competitive advantage and explain why you can't afford to delay in adopting this technology. He also gives some insights about how travel companies should organize their web content to become more discoverable by AI agents. Plus, we have news about a rollback of airline compensation rules and a hot tip about signing up for the industry's best familiarization tours. Insights from Dan Flores Dan had lots of exciting perspective about how artificial intelligence tools can benefit travel professionals. Here's what he had to say about how AI can give smaller operators a competitive edge: great things done. Here’s what he had to say about how he learned to build a great remote culture: “For a small tour operator or entrepreneur, it actually gives you opportunities. It democratizes scale. We're seeing more solo entrepreneurs build companies that they couldn't build in that time frame right now becoming millionaires because they can use AI to build all these things…. They don't have to have the cash flow to hire all of these people to do it. It makes two people, three people, five or six people operate as if they had 18, 20 or 25 people.” Plus, he had great perspectives on: How to build website chat bots people want to use How AI agents can save you time Integrating agentic AI into your travel sales pipeline Resources Mentioned in This Episode Learn more about Satisfi Labs at satisfilabs.com Follow Dan on LinkedIn. Sign up for our OnSite familiarization tour list at https://grouptravelleader.com/fams/. Key Moments From This Episode 1:08 — Travel News: DOT rolls back airline passenger compensation plan 2:22 — Be the first to know about our upcoming FAM trips 6:09 — The stunning growth of AI tools and adoption 8:11 — How Dan Flores uses AI in everyday life 12:49 — How AI is impacting tourism businesses 17:06 — A better way to answer customer questions 23:10 — Leveraging AI agents to serve customers better 30:06 — How close are we to fully automatic AI sales in travel? 31:46 — Optimizing your website to work with AI agents 34:48 — Will AI disrupt your travel career? Watch the Full Interview See the full interview with Dan on our YouTube channel. About the Podcast Gather and Go with Brian Jewell is a tourism industry podcast that helps group travel leaders plan, promote and lead better trips. There are also tips and insights for destination marketers and others who support the tourism trade. Each episode reaches thousands of professional tour operators, travel agents and the volunteer group leaders they serve. The audience also includes destination museum leaders, church travel leaders and other tourism enthusiasts around the world. Each show includes an interview with a smart travel pro or an insightful person from outside tourism who’s expertise can help make travel businesses better. You’ll also hear travel news, road tips and more. New episodes are released about twice monthly. You can find Gather and Go wherever your listen to podcasts or subscribe by email.

IT WAS GONNA BE A REALLY GOOD REALITY SHOW, FAM, WE SWEAR TO GODDESS! Ugh, in 2010, Lifetime TV ordered 8 episodes of a show called PI Moms. And it was supposed to be just as badass as it sounds: A group of women kicking ass, taking names, and solving crimes. The only problem is that WE CAN'T HAVE ANYTHING GOOD, and so it turns out, the whole enterprise was being run by a guy who not only didn't actually care about the show, but was also BUYING AND THEN SELLING DRUGS FROM A DIRTY COP, annnnnnnnd a completely different egomaniac dude was trying to derail the whole thing because the producers wouldn't make a show called PI MOMS ABOUT HIM. Like, you really can't make this stuff up. And there's a reason this (amazing) series is called Trainwreck. Ugh. ANYWAY GET READY TO HEAR US SCREAM FOR AN HOUR (sorry for yelling). Find and watch "Trainwreck: PI Moms" on Netflix WE'RE ON YOUTUBE - Want to view the episodes and not just listen?  Check our new video feed to see full video episodes starting today. CLICK HERE TO WATCH AND SUBSCRIBE! OUR MERCH STORE IS BACK - AND ON SALE!  Missed out on the merch drops earlier this year?  From now until the end of the year, you can grab all of our remaining stock of merchandise for 30% off!  Shop now!! LOOKING FOR MORE TCO? On our Patreon feed, you'll find over 400 FULL AD-FREE BONUS episodes to BINGE RIGHT NOW, including our episode-by-episode coverage of popular documentary series like Love Has Won: The Cult of Mother God, LulaRich, and The Curious Case of Natalia Grace; classics like The Jinx, Making A Murderer, and The Staircase; and well-known cases like The Menendez Murders, Casey Anthony: American Murder Mystery, and The Disappearance of Madeleine McCann, and so many more! Episode Sponsors: Miracle Made - Upgrade your sleep with Miracle Made! Go to https://trymiracle.com/TCO and use the code TCO to claim your FREE 3 PIECE TOWEL SET and SAVE over 40% OFF Uncommon Goods - make holiday shopping stress-free and joyful with thousands of one-of-a-kind gifts! Go to www.uncommongoods.com/TCO for 15% off! Our Place - Stop cooking with toxic cookware, and upgrade to Our Place today. Visit www.fromourplace.com/TCO for 35% off sitewide now through Jan 12th. Helix - Upgrade your sleep! Go to www.helixsleep.com/tco for 27% Off Sitewide!! Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!! And don't forget to join Gillian for the FINAL EPISODES of The Hamilcast, now through January 26! Celebrate an amazing decade of the show with us!

Justin Bruce is joined by music writer Josh Terry of the great No Expectations weekly indie music newsletter to discuss Eggy's three set show at Thalia Hall on November 15, 2025. They also chat about Eggy-adjacent indie music and pop music, why your favorite jam band artists don't only listen to jam bands, and touch on a few of Josh's 2025 movie highlights.Audience recording of Eggy's Thalia Hall show on November 15, 2025 from taper extraordinaire and friend of the pod Al W.Eggy's tour datesVice or Virtue is a proud part of Osiris Media.Follow Vice or Virtue on InstagramFollow Justin Bruce on MastodonFollow Vice or Virtue on BlueskyJoin the Green Eggs and Fam private Facebook group Hosted on Acast. See acast.com/privacy for more information.

Discover the can't-miss mattress industry events for 2026—plus the surprising secret to turning networking into real business growth!If you want to turn 2026 into your most successful year yet in the sleep and mattress industry, this is the episode you can't afford to miss. Mark Kinsley and Tara unveil The FAM's full 2026 calendar of events—including insider details about Sleep Summit, Dream Camp in Santa Barbara, exclusive Vegas Market parties, and more.You'll learn why showing up in-person is about more than just being there—it's about transforming your habits, your mindset, and your results. Hear how top industry leaders leverage these events to unlock new business opportunities, forge lifelong connections, and walk away with actionable ideas you simply can't get inside your own four walls.Plus: • The real reason traditions like the Coin Holders Party matter in a chaotic world • How to secure your spot at the most exclusive gatherings (and why spots fill up fast) • The mindset shift that can turn every event into your “beach vacation” for business growthWhether you're a retailer, manufacturer, or sleep health pro, get ready for expert insights, a few laughs, and your roadmap to next-level success in 2026.Timestamps:- 01:24 – "Why Sleep Summit 2025 was a game-changer for industry leaders"- 05:11 – "How to get invited to the exclusive Coin Holders Party"- 09:38 – "Santa Barbara Dream Camp: What makes this event so transformative?"- 14:15 – "The sleep industry's #1 networking mistake (and how to avoid it)"- 18:02 – "How to prepare for in-person events: The habits that set you apart"- 21:55 – "Unlocking hidden growth: The power of showing up as your best self"- 25:30 – "Hotel & travel hacks for Sleep Summit 2026—avoid these rookie mistakes"- 28:44 – "How to join the FAM community and never miss an opportunity"Connect with The FAM Podcast:

In this episode, Traci Grant shares her profound NPE journey, uncovering a hidden truth about her biological father after a lifetime of painful family dynamics and secrecy. Traci can be reached at tracigrant.com or traciygrant630@gmail.comResources Mentioned:After the Rotting by Traci GrantNPE Stories PatreonNPE Stories facebook pagehttps://www.facebook.com/NPEstories

"Antibody–drug conjugates (ADCs) have three basic parts: the antibody part, the cytotoxic chemo, and the linker that connects the two. First, the antibody part binds to the target on the surface of the cell. Antibodies can be designed to bind to proteins with a very high level of specificity. That's what gives it the targeted portion. Then the whole thing gets taken up by the cell and broken down, which releases the chemotherapy part. Some sources will call this the 'payload' or the 'warhead.'  That's the part that's attached to the 'heat-seeking' part, and that's what causes the cell death," Kenneth Tham, PharmD, BCOP, clinical pharmacist in general oncology at the University of Washington Medicine and Fred Hutchinson Cancer Center in Seattle, WA, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about antibody–drug conjugates. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by November 28, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the mechanism of action of antibody–drug conjugates. Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Pharmacology 101 series Episode 303: Cancer Symptom Management Basics: Ocular Toxicities Episode 283: Desensitization Strategies to Reintroduce Treatment After an Infusion-Related Reaction ONS Voice articles: An Oncology Nurse's Guide to Cancer-Related Ocular Toxicities Antibody–Drug Conjugates Join the Best of Two Worlds Into One New Treatment Nursing Management of Adverse Events From Enfortumab Vedotin Therapy for Urothelial Cancer Oncology Nurses' Role in Translating Biomarker Testing Results The Pharmacist's Role in Combination Cancer Treatments ONS Voice drug reference sheets: Belantamab mafodotin-blmf Datopotamab deruxtecan-dlnk Enfortumab vedotin Fam-trastuzumab deruxtecan-nxki ONS book: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) ONS course: ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ Clinical Journal of Oncology Nursing articles: Antibody–Drug Conjugates and Ocular Toxicity: Nursing, Patient, and Organizational Implications for Care Nurse-Led Grading of Antineoplastic Infusion-Related Reactions: A Call to Action Other ONS resources: Antineoplastic Administration Huddle Card Biomarker Database Chemotherapy Huddle Card Monoclonal Antibodies Huddle Card Association of Cancer Care Centers (ACCC) antibody–drug conjugates page Drugs@FDA Hematology/Oncology Pharmacy Association (HOPA) National Cancer Institute cancer drugs page Network for Collaborative Oncology Development and Advancement (NCODA) clinical resource library ACCC/HOPA/NCODA/ONS Patient Education Sheets website To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org Highlights From This Episode "The mechanism of action of the chemo itself depends on what agent or what 'warhead' is attached. Generally, [ADCs] have some kind of cytotoxic mechanism related to many of the chemotherapies that we use in practice, without attachment to the antibody. Some of them can be microtubule inhibitors, vinca alkaloids like vincristine. Some of them can be topoisomerase I (TOP1) inhibitors like irinotecan. Some can be alkylating agents that cause DNA breaks. So, again, looking back at the arsenal we have of cytotoxic chemo, these can all be incorporated into the ADCs." TS 5:54 "I want to talk about a case where the biomarker is being tested, but the biomarker isn't the target that you're looking for. One good case of this is a newer agent that was approved called datopotamab deruxtecan. The datopotamab portion is specific to a target called 'trophoblast cell surface antigen 2' (TROP2), which is expressed on the surface of many epithelial cancers. This agent was first approved in hormone receptor-positive, HER2-negative breast cancer, and received accelerated approval in patients with non-small cell lung cancer (NSCLC) with an EGFR mutation. ... The antibody looks for a target, TROP2. But in both of these cases—in the breast cancer and the NSCLC—you're testing for expression of different mutations or lack thereof. You're not looking for expression of TROP2. There's more research that needs to be done about the relationship between TROP2 expression and the presence or absence of these other biomarkers, but until we know more, we're actually testing for biomarkers that aren't the target of the ADC." TS 10:22 "There are common adverse advents to antibodies and chemo in general. Because we have both of these components, we want to watch out for the adverse effects of both of them. Antibodies, as with most proteins, can trigger an immune response or an infusion reaction. So, many ADCs can also cause hypersensitivity or infusion reactions. The rates of that are really variable and depend on the actual antibodies themselves. Then you have the cytotoxic component, the chemotherapy component, which has its own characteristic side effects. So, if we think of general chemo side effects—fatigue, nausea, bone marrow suppression, alopecia—these can [occur] with a lot of ADCs as well." TS 15:34 "The rate of ocular toxicity in [mirvetuximab soravtansine] is quite high. The manufacturer reports that this can occur in up to 60% of patients. With rates so high, the manufacturer recommends a preventive strategy. For this particular agent, [they] recommend patients have required eyecare. ... This ocular toxicity is something we do see in other ADCs that don't have the same target and don't necessarily have the same payload component. For example, tisotumab vedotin and again, datopotamab deruxtecan, can both cause ocular toxicities and both would have required ocular supportive care." TS 20:08 "Overall, I feel like the future is incredibly bright for these agents. There have only been around a dozen therapies approved by the U.S. Food and Drug Administration (FDA) despite this idea—the first agent came out in 2000. So, 25 years later, there are only around a dozen FDA-approved treatments. But there are so many more that are coming through the pipeline. And as we're discovering more biomarkers and developing more specialized antibodies, it's only natural that more ADCs will follow." TS 26:50

RIP the internet, Fam. Date of death:  Sometime in January 2020 when William White joined up! It started out innocent enough: some cute guy making lip-sync videos to 80s songs that made the ladies of a certain age swoon. But because we can't have anything nice, it all quickly went to hell. Fan groups formed, the bullying started, and the doxing, of course. And thennnnnnn William made a bunch of questionable choices. And we're gonna scream about it all. Join us, won't you? Find and watch "Thirst Trap: The Fame. The Fantasy. The Fallout" on Paramount+ WE'RE ON YOUTUBE - Want to view the episodes and not just listen?  Check our new video feed to see full video episodes starting today. CLICK HERE TO WATCH AND SUBSCRIBE! LOOKING FOR MORE TCO? On our Patreon feed, you'll find over 400 FULL AD-FREE BONUS episodes to BINGE RIGHT NOW, including our episode-by-episode coverage of popular documentary series like Love Has Won: The Cult of Mother God, LulaRich, and The Curious Case of Natalia Grace; classics like The Jinx, Making A Murderer, and The Staircase; and well-known cases like The Menendez Murders, Casey Anthony: American Murder Mystery, and The Disappearance of Madeleine McCann, and so many more! Episode Sponsors: Chewy - Every pet deserves a wish come true. Send your pet's wish to www.Chewy.com/ChewyClaus and it might become a reality. Plus, your wish means Chewy will donate five meals to pets in need. Quince - Upgrade your closet this year without the upgraded price tag. Go to www.Quince.com/tco for 365-day returns, plus free shipping on your order! Function - Visit www.functionhealth.com/TCO or use gift code TCO100 at sign-up to own your health. ButcherBox - ButcherBox delivers over 100 premium protein choices straight to your door! Go to www.ButcherBox.com/tco to get free steak in every box for a year  PLUS $20 off your first box!  Uncommon Goods - make holiday shopping stress-free and joyful with thousands of one-of-a-kind gifts! Go to www.uncommongoods.com/TCO for 15% off! Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!!

Comença el judici a la Família Pujol: ho comenten en Mohamed Jordi, en Jep Cabestany, en Benet Iñigo i l'Arnau Mañé. Comença el judici a la Família Pujol: ho comenten en Mohamed Jordi, en Jep Cabestany, en Benet Iñigo i l'Arnau Mañé. El Professor de Debò resol el misteri del judici dels Pujol.

How Scott Built a Multimillion-Dollar Mattress Business in a Town of 4,400What does it take to turn a tiny-town mattress store into a multimillion-dollar powerhouse? In this episode, Scott breaks down the mindset, systems, and sales strategies that transformed his business — and the insights are pure gold for any retailer.From the phrase that changed his store culture (“Best day in history”) to creating a contagious team energy, Scott reveals how elite retailers think, act, and WIN.Whether you're selling luxury mattresses, leading a retail team, or navigating tough economic seasons, this episode is stacked with actionable takeaways you can use today.03:05 — The sales phrase that changed everything (“Best day in history”)06:30 — Why average stores lose (and how to make your team contagious)10:45 — The ‘funk' mindset: Energizing teams and crushing comfort zones15:55 — Elite vs. average: What Sleep Summit taught top retailers21:55 — The untold secret to selling luxury mattresses to ANY customer24:30 — Adjustable base “flat” button: The four-letter word you should never say28:57 — Why advertising in a recession is your secret weapon (with hard numbers)41:05 — The ‘bed bundle' strategy: Effortless upsells that delight customers51:30 — Unreasonable hospitality: Turning friction into fun and fansWhat's YOUR #1 tip for bringing the funk and standing out in retail? Drop it in the comments!Join thousands of sleep-optimizers and business leaders sharing their best ideas every week — subscribe and be part of The FAM.Ready to transform your business? Reach out to Scott or visit thefam.com for more insider strategies.LinkedIn: https://www.linkedin.com/company/the-fam-mattress/TikTok: https://www.tiktok.com/@forallthingsmattressInstagram: https://www.instagram.com/forallthingsmattress/?hl=enFacebook: https://www.facebook.com/thefamnewsSpotify: https://open.spotify.com/show/4wvSqPZaxehCSmwRpByLi4?si=65a6aa9c5be54b58Apple Podcast: https://podcasts.apple.com/us/podcast/the-fam-podcast-with-mark-kinsley/id1452601818#MattressIndustry #SleepScience #RetailSuccess #CustomerExperience #BringTheFunk

On November 28, 1974, 28-year-old Karen Silkwood was killed in a car wreck on Highway 74 near Crescent, Oklahoma. Her death was officially ruled an accident. But her friends, family, and co-workers knew the real story: she had been killed for what she knew - and what she was about to do about it. In her car was a folder full of evidence that she was about to turn over to the New York Times detailing the plutonium  contamination of herself and her fellow workers at the local nuclear energy plant, and, crucially, evidence that the plant and THE UNITED STATES GOVERNMENT, was complicit in nuclear proliferation - AKA GIVING FOREIGN POWERS THE TOOLS TO MAKE NUCLEAR WEAPONS. Gird your loins, Fam, because we are not having it! Find and watch "What Happened to Karen Silkwood? The Lost Tapes" on Hulu WE'RE ON YOUTUBE - Want to view the episodes and not just listen?  Check our new video feed to see full video episodes starting today. CLICK HERE TO WATCH AND SUBSCRIBE! LOOKING FOR MORE TCO? On our Patreon feed, you'll find over 400 FULL AD-FREE BONUS episodes to BINGE RIGHT NOW, including our episode-by-episode coverage of popular documentary series like Love Has Won: The Cult of Mother God, LulaRich, and The Curious Case of Natalia Grace; classics like The Jinx, Making A Murderer, and The Staircase; and well-known cases like The Menendez Murders, Casey Anthony: American Murder Mystery, and The Disappearance of Madeleine McCann, and so many more! Episode Sponsors: Kettle and Fire - For a limited-time, you can get a free carton of Kettle & Fire bone broth by going to www.KettleAndFire.com/TCO Against The Odds - Follow Against The Odds on the Wondery App or wherever you get your podcasts, or binge all episodes early and ad-free right now on Wondery+ Chime - Make progress towards a better financial future with Chime. Open your account in 2 minutes at www.chime.com/TCO Home Chef -  Make cooking simple: fresh food delivered, easy recipes to follow and meals that actually taste great. Go to www.HomeChef.com/TCO for 50% off your first box and free dessert for life! Everyday Dose - Coffee with benefits! Visit www.everydaydose.com/TCO for  61% off your first subscription order! Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!!

Give it up for forensic genealogists, Fam!!!  We're getting into the science today, but also getting into all the feels as the DNA Doe Project brings answers to a cold case from the 1980s.  When these investigators start looking into a pair of unidentified remains from coroner Scott McCord's office, they not only connect them to a serial killer but also find and bring peace to relatives who lost track of their loved ones decades ago. Find and watch "Naming the Dead: The Hitchhiker" on Hulu or Disney+ WE'RE ON YOUTUBE - Want to view the episodes and not just listen?  Check our new video feed to see full video episodes starting today. CLICK HERE TO WATCH AND SUBSCRIBE! LOOKING FOR MORE TCO? On our Patreon feed, you'll find over 400 FULL AD-FREE BONUS episodes to BINGE RIGHT NOW, including our episode-by-episode coverage of popular documentary series like Love Has Won: The Cult of Mother God, LulaRich, and The Curious Case of Natalia Grace; classics like The Jinx, Making A Murderer, and The Staircase; and well-known cases like The Menendez Murders, Casey Anthony: American Murder Mystery, and The Disappearance of Madeleine McCann, and so many more! Episode Sponsors: Earnin - Get access to your pay as you work. Download the Earnin app in the Google Play or Apple app store. Hiya - The pediatrician-approved superpowered chewable vitamin. Receive 50% off your first order at www.hiyahealth.com/TCO Cornbread Hemp -  CBD gummies made to help you feel better! Head to www.cornbreadhemp.com/TCO and use code TCO at checkout for 30% off your first order!  Bilt - Earn points on rent and around your neighborhood, wherever you call home, by going to www.joinbilt.com/tco DripDrop - Doctor-developed hydration that works faster than water alone. Use promo code TCO at www.dripdrop.com for 20% off your first order! Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!!

Pull over, Fam, because we're covering a brash politician whose divisive style led him to victory.  But wait - in Canada?  That's right: Rob Ford would rise to become the mayor of Toronto, but no amount of bravado could prevent his downfall after an infamous video of him was leaked to the press. Find and watch "Trainwreck: Mayor of Mayhem" on Netflix WE'RE ON YOUTUBE - Want to view the episodes and not just listen?  Check our new video feed to see full video episodes starting today. CLICK HERE TO WATCH AND SUBSCRIBE! LOOKING FOR MORE TCO? On our Patreon feed, you'll find over 400 FULL AD-FREE BONUS episodes to BINGE RIGHT NOW, including our episode-by-episode coverage of popular documentary series like Love Has Won: The Cult of Mother God, LulaRich, and The Curious Case of Natalia Grace; classics like The Jinx, Making A Murderer, and The Staircase; and well-known cases like The Menendez Murders, Casey Anthony: American Murder Mystery, and The Disappearance of Madeleine McCann, and so many more! Episode Sponsors: IQ Bar - The better for you, plant protein snacks. Text TCO to 64000 to get 20% off your order! ButcherBox - ButcherBox delivers over 100 premium protein choices straight to your door! Go to www.ButcherBox.com/TCO to get free turkey or ham in your first box, or choose ground beef for life - PLUS $20 off your first box! Our Place - Stop cooking with toxic cookware, and upgrade to Our Place today. Visit www.fromourplace.com/TCO and use code TCO for 10% off sitewide. Ritual - Ritual's Essential for Women 18+ is a multivitamin you can actually trust. Get early access to the Black Friday sale for 40% off your first month at www.Ritual.com/TCO Function - Visit www.functionhealth.com/TCO or use gift code TCO100 at sign-up to own your health. Join the TCO Community! Follow True Crime Obsessed on Instagram and TikTok, and join us on Facebook at the True Crime Obsessed Podcast Discussion Group!  AND INTRODUCING THE NEW TCO DISCORD CHANNEL AS WELL!!!