The Metabolic Link

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health and therapy, and earn CMEs here!In this deeply personal and courageous episode of The Metabolic Link, we hear from patient advocate and podcast co-host Matt Baszucki, who shares how he endured—and ultimately overcame—type 1 bipolar disorder through a radical shift in treatment: ketogenic metabolic therapy.After years of hospitalizations, debilitating mood episodes, and failed conventional treatments, Matt found hope through the emerging field of metabolic psychiatry. With the help of his family, including support and clinical guidance from Dr. Christopher Palmer, Matt adopted a therapeutic ketogenic diet in 2021—and the results were extraordinary.Now a thriving project manager in Silicon Valley and co-host of The BipolarCast, Matt is helping drive a movement that challenges the very foundation of how we treat mental illness. This episode is not just about recovery—it's about transformation, resilience, and the future of mental health care.Special thanks to the sponsors of this episode:✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here✅ iRestore – Get a huge discount when you use the code METABOLICLINK hereWatch Matt Baszucki's YouTube Channel here and Bipolar Cast here. Learn more about the non-profit, Metabolic Mind, here. In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here!If you're a clinician, scientist, or anyone interested in taking a deep dive into the complexities of hormone regulation, this episode of The Metabolic Link Podcast is for you! Recorded live at Metabolic Health Summit 2024, this in-depth presentation by Dr. Kyle Gillett—dual board-certified in family and obesity medicine—dives deep into the biochemical, clinical, and therapeutic layers of hormone health.From his foundational “Seven Pillars of Health” to cutting-edge insights on peptides, receptor affinity, and hormone testing strategies, Dr. Gillett provides a masterclass on optimizing hormones for performance, longevity, and metabolic resilience. Designed for professionals and educated listeners alike, this talk bridges clinical relevance with scientific nuance.Access even more from Dr. Gillett—like his exclusive Hormones 101 lecture—inside our medical education platform, The Metabolic Initiative. Start your free trial at https://membership.metabolicinitiative.com.Special thanks to the sponsors of this episode:✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here✅ Fatty15 – Get 15% off a 90-day Starter Kit with the code METABOLICLINK here ✅ Zocdoc – Find and instantly book a top-rated doctor here✅ Puori – Get 20% off supplements with code METABOLICLINK hereLearn more about Dr. Gillett here!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.comIn today's journal club episode, co-hosts of The Metabolic Link, Dr. Angela Poff and Dr. Dominic D'Agostino, unpack the startling rise of non-alcoholic fatty liver disease (NAFLD)—a silent epidemic affecting millions worldwide. Tune in as they break down groundbreaking new research revealing how NAFLD isn't just impacting adults, but alarmingly, children and adolescents too.You'll learn about the latest updates in terminology, such as Metabolic Dysfunction Associated Steatohepatitis (MASH) and Metabolic Dysfunction Associated Steatotic Fatty Liver Disease (MASLD), highlighting a critical connection to underlying metabolic dysfunction. Plus, discover exciting dietary strategies—like therapeutic carbohydrate restriction—that hold potential not just to prevent, but to actually reverse liver fat accumulation.If you've ever wondered how your diet and lifestyle choices directly shape your metabolic health, this episode delivers practical insights and actionable information straight from cutting-edge science. Don't miss this deep dive into the latest science on NAFLD—and how simple shifts today could dramatically improve your metabolic health tomorrow.Special thanks to the sponsors of this episode:Genova Connect – Get 15% off any test kit with code METABOLICLINK hereMaui Nui Venison: Gain access to a limited collection of our favorite Maui Nui products hereiRestore: Use code METABOLICLINK for exclusive discounts on the iRestore Illumina Face Mask here Puori – Get 20% off supplements with code METABOLICLINK hereRead the papers discussed here: https://pubmed.ncbi.nlm.nih.gov/38521116/ https://pubmed.ncbi.nlm.nih.gov/38914224/https://pubmed.ncbi.nlm.nih.gov/38771552/https://pubmed.ncbi.nlm.nih.gov/38723301/ In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Join us for a FREE Live Q&A with Dr. Spencer Nadolsky on April 22nd at 9am PT / 12pm ET! Your first seven days are free, and as a member of The Metabolic Initiative, you'll gain access to exclusive, ad-free episodes, hundreds of expert-led videos on metabolic health and therapy, CME opportunities, and more here!In this episode of The Metabolic Link, Dr. Dominic D'Agostino sits down with Dr. Spencer Nadolsky—board-certified obesity and lipid specialist, former NCAA heavyweight wrestler, and founder of Vineyard—to explore one of the most hotly debated and often misunderstood tools in modern medicine: GLP-1 receptor agonists.Together, they take a deep dive into how these drugs work, who they're for, and why they might not always be a magic bullet. Dr. Nadolsky shares clinical insights into the real-world use of semaglutide, tirzepatide, and combination therapies, breaking down everything from appetite regulation and side effects to muscle loss, mood changes, and the potential future of prevention.They also tackle pediatric obesity, long-term use vs. off-ramping, and the critical role of resistance training and nutrition for protecting muscle mass while on these medications.Special thanks to the sponsors of this episode:✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here✅ Fatty15 – Get 15% off a 90-day Starter Kit here (use code METABOLICLINK)✅ Zocdoc – Find and instantly book a top-rated doctor here✅ Puori – Get 20% off supplements with code METABOLICLINK here

Join us for a Live Q&A with Dr. Ovadia on March 31st at 12 PM PT / 3 PM ET! Your first seven days are free, and as a member of The Metabolic Initiative, you'll gain access to exclusive, ad-free episodes, hundreds of videos on metabolic health (including Dr. Ovadia's presentation, Fanning the Flames: Inflammation, Insulin Resistance, and Heart Disease), CME opportunities, and more. Register here!Dr. Philip Ovadia is a cardiac surgeon on a mission to change how we think about heart disease. After performing thousands of surgeries, he realized that most of his patients didn't need to end up on his operating table in the first place. In this episode, Dr. Ovadia joins host Victoria Field to uncover the metabolic factors driving heart disease and explore how we can prevent it before it requires surgery.They dive into key topics like the role of insulin resistance versus cholesterol, why he says inflammation should be a bigger focus than LDL, the importance of advanced testing like Coronary Artery Calcium Score scans, and why lifestyle changes are the true foundation of prevention. Dr. Ovadia also shares his personal journey from obesity to metabolic health and how it reshaped his entire approach to medicine.Whether you're a patient, physician, or anyone passionate about heart health, this episode will give you the tools you need to avoid the operating table.Special thanks to the sponsors of this episode:✅ Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK here✅ Maui Nui Venison: Gain access to a limited collection of our favorite Maui Nui products here ✅ Zocdoc: Visit this link to find and instantly book a top-rated doctor✅ Puori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Visit this link and use the code METABOLICLINKLearn more about Dr. Ovadia here!Join our Live Q&A with Dr. Ovadia: https://membership.metabolicinitiative.com/ovadia In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Mitochondria do more than power our cells—they may hold the key to understanding and treating mental illness.In this episode of The Metabolic Link, Dr. Dominic D'Agostino sits down with Dr. Ana Andreazza, a leading expert in mitochondrial health at the University of Toronto.Dr. Andreazza has pioneered research linking mitochondrial dysfunction to psychiatric disorders like bipolar disorder, utilizing groundbreaking 3D brain organoid models to study neurotransmission. She also leads research on mitochondrial transplantation, a potential game-changer in regenerative medicine.Join us as we explore how mitochondria influence mood, metabolism, and overall health—and why optimizing mitochondrial function may be the future of medicine. Listen to the episode on any major podcast player or watch the interview on YouTube.Learn more about Dr. Andreazza's work here.Special thanks to our sponsors:Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK hereFatty15: Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK hereMUD/WTR: Start your new morning ritual & get up to 43% off your MUDWTR with code METABOLICLINK herePuori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Visit this link and use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here.What's the best way to optimize metabolic health? In this powerhouse episode of The Metabolic Link, we bring together leading experts including Dr. Ben Bikman, Dr. Richard Johnson, Dr. Jonathan Jun, Dr. Nick Norwitz, and Dave Feldman from our Optimizing Metabolic Health Symposium filmed at Metabolic Health Summit 2024 and hosted by Dr. Dominic D'Agostino.In this discussion, you'll dive into some of the biggest questions in metabolism, including:What are the long-term effects of GLP-1 medications on fat, muscle, and metabolism?Does long-term dieting slow metabolism? And if so, can you reverse it?How do diet and fasting influence neuropathy and nerve function? Exercise and lipid profiles—what makes an athletic metabolism different?Do high-protein diets really harm the kidneys, or is it a myth?What is the role of the microbiome in weight gain, fat loss, and metabolic adaptation?And much more! With insights from top scientists and researchers, this episode is packed with takeaways for anyone looking to improve their metabolic health.Special thanks to the sponsors of this episode:Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK hereMaui Nui Venison: Gain access to a limited collection of our favorite Maui Nui products hereZocdoc: Visit this link to find and instantly book a top-rated doctorPuori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

What if we could target cancer at its metabolic core? In this episode of The Metabolic Link, Dr. Dominic D'Agostino is joined by Dr. Tomás Duraj, a physician and cancer metabolism researcher working alongside Dr. Thomas Seyfried.Dr. Duraj is the lead author of a groundbreaking review on ketogenic metabolic therapy for glioblastoma, bringing together leading experts to explore how metabolic strategies could reshape cancer treatment.In this deep-dive conversation, they discuss the bioenergetics of cancer, the role of mitochondria, the Warburg effect, and why targeting glucose and glutamine metabolism may be the key to making standard cancer therapies more effective.Whether you're a researcher, clinician, or someone interested in the latest advancements in cancer therapy, this episode is packed with insights that could redefine the way we think about cancer treatment. Watch the full episode here or listen on your favorite podcast player for this must-hear discussion on the future of metabolic therapy for cancer!Read Dr. Duraj's paper: Clinical research framework proposal for ketogenic metabolic therapy in glioblastomaAbout Dr. Tomás DurajDr. Tomás Duraj is a Czech physician-scientist, receiving his Medical Degree from the Rey Juan Carlos University and his PhD in Translational Medicine from the CEU San Pablo University (Madrid, Spain). His research focuses on studying the potential of bioenergetic modulation in cancer metabolism, with special emphasis on glioblastoma, the most aggressive and lethal primary brain tumor. After developing cancer research at the team of Dr. Ayuso Sacido, he joined Dr. Thomas N. Seyfried's laboratory in Boston College. His goal is to advance our understanding of metabolic oncology on a rigorous, evidence-based background, making it part of the standard oncology toolkit.Special thanks to the sponsors of this episode:Puori: Get 20% off Puori supplements at https://puori.com/METABOLICLINK and use the code METABOLICLINKFatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/METABOLICLINK and use code METABOLICLINK.MUDWTR: Get up to 43% off with code METABOLICLINK at https://mudwtr.com/METABOLICLINKIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com Can a ketogenic diet revolutionize the management of type 1 diabetes? In this episode of The Metabolic Link, Dr. Ian Lake, a UK-based physician and type 1 diabetes advocate, shares his personal and professional journey in using low-carb and ketogenic diets to improve metabolic control.Diagnosed with type 1 diabetes at 36, Dr. Lake initially followed conventional high-carb recommendations—until he discovered the power of nutritional ketosis. He breaks down how reducing insulin volumes, optimizing glucose levels, and becoming fat-adapted transformed his health and life.From running 700 miles while following a ketogenic diet to leading type 1 diabetes retreats, Dr. Lake shares actionable insights on metabolic flexibility, insulin sensitivity, and the real-world implications of a ketogenic approach.Special thanks to the sponsors of this episode:Puori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Visit https://puori.com/METABOLICLINK and use the code METABOLICLINKMaui Nui Venison: Gain access to a limited collection of Dom's favorite Maui Nui products at https://mauinuivenison.com/METABOLICLINKZocdoc: Visit https://Zocdoc.com/METABOLICLINK to find and instantly book a top-rated doctorIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, watch 100s of videos on metabolic health, and earn CMEs here.In this powerful and unfiltered episode of The Metabolic Link, we're sharing a full presentation by Chad Vanags, a former SaaS executive and entrepreneur who has turned his stage 4 lung cancer diagnosis into a mission to reshape the way we think about healing. Recorded live at Metabolic Health Summit in January of 2024, Chad shares his journey of becoming metabolically, physically, and mentally elite in the fight against cancer.Through his deeply personal story, Chad provides a rare and essential patient perspective, shedding light on the gaps in traditional cancer care—from nutrition and communication to the importance of mindset and metabolic health. His insights challenge clinicians, researchers, and patients alike to rethink the medical status quo, spark innovation, and inspire transformative conversations.This episode is more than just a story of resilience—it's a call to action to integrate patient voices into the heart of healthcare and foster a collaborative approach to healing.Listen to this episode or watch on YouTube to explore Chad's journey, the lessons he's learned, and his hope for the future of patient-centered care.Special thanks to the sponsors of this episode:Fatty15: Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK at fatty15.com/METABOLICLINKMUD/WTR: Start your new morning ritual & get up to 43% off your MUDWTR with code METABOLICLINK at mudwtr.com/METABOLICLINKIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here. In this journal club episode, host Victoria Field is joined by Dr. Angela Poff and Dr. Dominic D'Agostino to dive into two groundbreaking studies shaping our understanding of metabolism and its role in health and disease. The team explores the nuances of a recent randomized controlled trial on ketogenic diets, free sugar restriction, and their effects on glucose tolerance, lipid metabolism, and the gut microbiome. Then, they tackle a cutting-edge study uncovering the molecular mechanisms of ketogenic diets in reshaping cancer metabolism through lysine beta-hydroxybutylaration.From the clinical implications of these findings to the potential of ketone supplementation, this episode is packed with insights for researchers, clinicians, and health enthusiasts. Don't miss the opportunity to learn how these discoveries could shape the future of precision medicine.

Join our free Live Q&A with Lauren on December 18th and become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Register here!In this episode of The Metabolic Link, host Victoria Field sits down with Lauren Kennedy West, a passionate mental health advocate and social worker who was diagnosed with schizoaffective disorder in 2016. Lauren reveals her extraordinary journey of using metabolic therapy to not only manage but reverse debilitating symptoms, transforming her life in ways she once thought impossible.This deeply compelling conversation delves into Lauren's personal story, the stigma surrounding mental health, and the challenges of balancing medications with metabolic therapy. Lauren also shares her mission to bring metabolic therapy to the forefront of mental health treatment, redefining possibilities in the field of metabolic psychiatry.Lauren's bravery and advocacy are sparking new conversations about recovery and shining a light on the untapped potential of metabolic approaches to mental health. Don't miss this inspiring episode—and be sure to join Lauren for a Live Q&A on December 18th through The Metabolic Initiative platform. Learn more here!Special thanks to the sponsor of this episode: Genova Connect: Gain access to advanced lab tests in the comfort of your own home. Receive 15% off any test with code metaboliclink by clicking here.AG1: New subscribers get a FREE $76 gift when you sign up. You'll get a Welcome Kit, a bottle of D3K2 AND 5 free travel packs in your first box. Visit this link.Ned: Get 15% off Ned products with code METABOLICLINK by visiting this link.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.comIn this special episode of The Metabolic Link, we're sharing an exclusive panel discussion from Metabolic Health Summit 2024, where leading experts dive into the science and real-world applications of allulose, a natural low-calorie sweetener with potential metabolic health benefits.Featuring insights from Dr. Richard Johnson, Dr. Jeff Volek, Dr. Ben Bikman, Dr. Andrew Koutnik, and Dr. Dominic D'Agostino, this conversation explores how allulose influences glucose levels, insulin sensitivity, weight management, and GLP-1 stimulation for satiety and glucose control. The panel also addresses questions about safety, its role as a sugar substitute, and its potential impact on broader metabolic pathways.Whether you're new to allulose or looking to deepen your understanding of metabolic health, this episode offers valuable perspectives from some of the field's top researchers.Special thanks to the sponsor of this episode: Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink AG1: New subscribers get a FREE $76 gift when you sign up. You'll get a Welcome Kit, a bottle of D3K2 AND 5 free travel packs in your first box. Visit: https://DrinkAG1.com/METABOLICLINKNed: Get 15% off Ned products with code METABOLICLINK at https://helloned.com/metaboliclinkIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com In this episode of The Metabolic Link filmed at Metabolic Health Summit 2024, Dr. Valter Longo shares his latest research on the fasting mimicking diet (FMD) and its powerful impact on aging, metabolic diseases, and cancer treatment. With a focus on periodic fasting interventions, Dr. Longo highlights the role of FMD in activating stem cells, enhancing cellular repair mechanisms, and even reversing metabolic dysfunctions like insulin resistance and type 1 diabetes.Dr. Longo's work is paving the way for more accessible, non-invasive therapies for chronic conditions, with far-reaching implications for aging, cancer prevention, and metabolic health. If you're an academic, medical professional, or researcher, you won't want to miss this in-depth discussion on how FMD could shape the future of medicine.Valter Longo, PhD, is the Edna Jones Professor in Gerontology, the Director of the USC Longevity Institute and group leader at the IFOM cancer research institute in Milan, Italy. His laboratories study the fundamental mechanisms of aging in yeast, rodents and humans by using genetics and biochemistry techniques. The focus is on the nutrient-response signal transduction pathways that regulate disease and longevity. This work led to the discovery of the effects of periodic fasting and fasting mimicking diets on multi-system stem cell activation and regeneration in mice, and to clinical trials on a range of age-related diseases.Special thanks to the sponsors of this episode: Genova Connect: Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclinkAG1: This November, AG1 is offering a free gift with your first subscription plus a Welcome Kit at https://DrinkAG1.com/METABOLICLINK—while supplies last!Ned: Get 15% off Ned products with code METABOLICLINK at https://helloned.com/metaboliclinkLearn more about Dr. Valter Longo here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.comIn this episode of the Metabolic Link podcast, we are joined by Beth Zupec-Kania, an experienced dietitian and nutritionist with over 30 years in the field of ketogenic metabolic therapy. Beth has played a pivotal role in the development and implementation of ketogenic diets for the treatment of epilepsy, and her work has expanded to include a variety of neurological and psychiatric conditions, including anorexia nervosa, bipolar disorder, and schizophrenia.Beth's expertise is shaped by years of practical experience and her involvement with The Charlie Foundation, where she helped pioneer the use of ketogenic metabolic therapy in clinical settings. In this episode, we explore how this therapy has evolved from a treatment for refractory epilepsy to a promising option for mental health conditions and other complex disorders.We discuss the latest evidence supporting ketogenic therapy, its application in clinical practice, and the challenges healthcare providers face in integrating these therapies into standard care. Beth also shares her insights into the future of metabolic therapies in healthcare, highlighting the growing need for education and clinical expertise in this transformative area.If you're a medical professional interested in understanding how ketogenic metabolic therapies can improve patient outcomes across a range of conditions, this episode is a must-listen.Special thanks to the sponsors of this episode: Genova Connect: Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclinkNed: Get 15% off Ned products with code METABOLICLINK at helloned.com/metaboliclink Learn more about Beth Zupec-Kania here: https://www.bethzupeckania.comIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.comIn this episode, we're sharing a presentation from Metabolic Health Summit 2024 that dives into a groundbreaking experiment titled "Oreo vs. Statin," by researcher-educator Nick Norwitz, PhD. What started as a personal journey with metabolic health turned into a captivating exploration of the lipid energy model and lean mass hyper responders. Dr. Norwitz shares the dramatic results of his unorthodox study, where a diet consisting primarily of Oreos led to a jaw-dropping 70% reduction in LDL cholesterol. We discuss the implications of his findings, the challenges he's faced in the scientific community, and the importance of asking uncomfortable questions in pursuit of knowledge. This episode is an opportunity to watch an engaging lecture filled with scientific awe, unexpected results, and a call to action for more open-minded discussions in metabolic health!Dr. Nick Norwitz has a mission to “Make Metabolic Health Mainstream.” He graduated Valedictorian from Dartmouth College in 2018, majoring in Cell Biology and Biochemistry. He then completed his PhD in Metabolism at the University of Oxford in 2021, before attending Harvard Medical School to complete his MD. Dr. Norwitz enthusiasm for the field of Metabolism derives from a personal struggle with severe Inflammatory Bowel Disease that left him physically emaciated, mentally depleted, and emotionally fragmented. In desperation, he found that a ketogenic diet put his disease into remission where conventional approaches had failed.Special thanks to the sponsor of this episode: Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclinkLearn more about Dr. Norwitz here: https://www.nicknorwitz.comIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Did you know that nearly 60% of the average American's diet is made up of ultra-processed foods? This staggering statistic highlights a growing public health crisis linked to rising obesity rates and chronic diseases, not only in adults but our children too.In this week's episode of The Metabolic Link, we dive into a critical conversation with Todd Wagner, a passionate advocate for food safety and health reform. As the founder of FoodFight USA, Todd is dedicated to cleaning up America's tainted food supply and empowering consumers by raising awareness about the dangers of ultra-processed foods. He is also known for his entrepreneurial success as the co-founder and CEO of Broadcast.com, which he sold to Yahoo! for $5.7 billion, and for founding the Todd Wagner Foundation, which supports technology programs for at-risk children.Today, we explore Todd's mission with FoodFight USA, a nationwide campaign focused on promoting healthier food choices and advocating for legislative change. With the powerful mantra, “Good food is medicine, and bad food requires medicine,” we discuss the stark differences between the U.S. and European food systems, the alarming prevalence of synthetic chemicals in our food supply, and the urgent need for reform.Todd provides valuable insights into the existing regulatory framework, pointing out the issues arising from food companies' ability to self-regulate. We also explore the grassroots efforts driving FoodFight USA and discuss practical steps listeners can take to become more informed consumers and advocate for healthier food options.Join us for this eye-opening discussion that emphasizes the importance of “clean” food and the necessity of a collaborative approach to address these pressing issues. Learn how you can contribute to the solution and help shape a healthier future with FoodFight USA!Special thanks to the sponsors of this episode:Genova Connect - Receive 15% off any of their tests with code METABOLICLINK hereFatty15 - Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK hereNed - Get 15% off Ned products with code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here.In this journal club episode of The Metabolic Link, we explore the cutting-edge "Metabolic Overdrive Hypothesis" with Dr. Dominic D'Agostino, Dr. Angela Poff, and Victoria Field, diving into the brain's energy dysregulation in bipolar disorder. The featured paper, "The Metabolic Overdrive Hypothesis: Hyperglycolysis and Glutaminolysis in Bipolar Mania", by authors Dr. Iain Campbell and Dr. Harry Campbell, proposes that mitochondrial dysfunction forces the brain into a hypermetabolic state, leading to manic episodes.We discuss how this groundbreaking research links bipolar disorder to epilepsy and how therapeutic ketosis—through diet or supplementation—might restore energy balance, reduce manic episodes, and complement traditional medications.With the potential to reshape psychiatric treatment, you won't want to miss this paper or journal club episode! Read the full paper here: https://www.nature.com/articles/s41380-024-02431-wSpecial thanks to the sponsors of this episode:Genova Connect - Receive 15% off any of their tests with code METABOLICLINK hereFatty15 - Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK hereNed - Get 15% off Ned products with code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In our 50th episode of The Metabolic Link podcast, host Dr. Dominic D'Agostino dives deep into the fascinating world of metabolic health through an unexpected lens — bottlenose dolphins. Dr. Stephanie Venn-Watson, a veterinary epidemiologist and public health scientist, joins the show to share her groundbreaking research with the U.S. Navy's Marine Mammal Program, where dolphins helped reveal the essential role of C15:0. C15:0 is an odd-chain saturated fatty acid that has 3-times more cellular benefits than omega-3s. Dr. Venn-Watson surprisingly discovered that C15:0 (also called pentadecanoic acid) is an essential fatty acid - the first to be found in over 90 years. In this episode, we discuss how C15:0 plays an important role in longevity and metabolic health, its potential to reduce inflammation, improve mitochondrial function, and why it's crucial for both dolphins and humans. Learn how this unique fatty acid is transforming our understanding of insulin resistance and why it could be a game-changer in human health. Plus, Dr. Venn-Watson also shares the exciting future of this essential fatty acid in human health research.About Dr. Stephanie Venn-WatsonDr. Stephanie Venn-Watson is the CEO of Seraphina Therapeutics. A seasoned veterinary epidemiologist and public health scientist, Stephanie previously served at the World Health Organization and U.S. Navy. With a life-long mission of helping people (and our fellow animals) age better, Stephanie's award-winning approach to improving human and animal health has been featured on NPR, BBC, CBS, and National Geographic. In her time as CEO, Seraphina Therapeutics has been recognized for its extensive research and education on pentadecanoic acid (C15:0). Dr. Venn-Watson is also the co-founder of Fatty15. Fatty15 is a science-backed and award-winning C15:0 supplement to support our long-term health and wellness. Stephanie received her B.S. in Animal Physiology and Neuroscience from UC San Diego, D.V.M. from Tufts University, M.P.H. from Emory University, and was a National Research Council Associate with the Armed Forces Medical Intelligence Center. She is an Albert Schweitzer Fellow for Life.Special thanks to our episode sponsors:* Genova Connect - Get 15% off with code METABOLICLINK here* AquaTru - Get 20% off with the code METABOLICLINK here* Ned - Get 15% off with code METABOLICLINK hereThis episode is not sponsored by Fatty15, but they're a partner of The Metabolic Link. Get 15% off their 90-day subscription Starter Kit by clicking here and using code METABOLICLINKIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.comIn this episode of The Metabolic Link, recorded at Metabolic Health Summit 2024, we share Dr. Jeff Volek's full presentation where he takes a deep dive into the "Keto-Adapted Phenotype" with a focus on muscle. Dr. Volek, a leading expert in low-carbohydrate and ketogenic diets, shares groundbreaking research on how ketones impact muscle function and performance. Dr. Volek explores the intricate ways ketones influence muscle glycogen metabolism, ketone production in skeletal muscle, and even heart function.Dr. Volek unpacks underappreciated aspects of ketosis, such as how muscle glycogen can be preserved and replenished without the need for high carbohydrate intake, the role of ketones in cardiac health, and how skeletal muscles may play a part in ketone metabolism. This thought-provoking episode not only challenges conventional ideas about energy and performance but also offers insights for athletes, health professionals, and anyone interested in optimizing metabolic health.About Dr. VolekDr. Volek is a registered dietitian and professor in the Department of Human Sciences at The Ohio State University. For the last 25 years, he has performed translational research on how humans adapt to ketogenic diets with a dual focus on clinical and performance applications of nutritional ketosis. His scholarly work includes more than 350 peer-reviewed scientific manuscripts and five books. Dr. Volek is the Chief Science Officer and Co-Founder of Virta Health, the first clinically proven treatment to safely and sustainably reverse type 2 diabetes at scale without medications or surgery. Dr. Volek has a Bachelor of Science in dietetics from Michigan State University, and a Master of Science in exercise physiology and Doctorate in kinesiology and nutrition from Pennsylvania State University.Special Thanks to our Episode Sponsors: * Genova Connect, powered by Genova Diagnostics - Receive 15% off any of their tests with code METABOLICLINK: https://connect.gdx.net/themetaboliclink* Fatty 15 - Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK: https://fatty15.com/METABOLICLINK* Ned - Get 15% off Ned products with code METABOLICLINK at http://helloned.com/metaboliclinkIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Join Dr. Norwitz for a Live Q&A on September 10th at 12pm PT/3pm ET on The Metabolic Initiative platform! Visit this link to register, and also watch his presentation Cookies & Cholesterol Controversy inside the platform (first 7-days are free): https://membership.metabolicinitiative.com/norwitzIn this episode, Dr. Nick Norwitz returns to The Metabolic Link podcast to explore the future of personalized medicine and the evolution of metabolic health research with host, Dr. Dominic D'Agostino. Join us as they dive into the landscape of traditional randomized control trials, the rise and evolution of individualized health protocols, and the exciting potential of multiomics and continuous glucose monitoring in shaping a new era of healthcare. Dr. Norwitz, a passionate advocate for science communication and education, shares his insights on how emerging technologies and personalized approaches can revolutionize medicine, empowering individuals to take control of their metabolic health. Dr. Norwitz also shares his unique career journey and aspirations, providing valuable insights and advice for pre-med and medical students. Whether you're a medical professional, student, or health enthusiast, this episode offers a thought-provoking glimpse into the next frontier of medicine.About Dr. NorwitzDr. Nick Norwitz is a researcher-educator whose mantra is “Stay Curious” and whose mission is to “Make Metabolic Health Mainstream.” He graduated Valedictorian from Dartmouth College in 2018, majoring in Cell Biology and Biochemistry. He then completed his PhD in Metabolism at the University of Oxford in 2021, before attending Harvard Medical School to complete his MD. Dr. Norwitz enthusiasm for the field of Metabolism derives from a personal struggle with severe Inflammatory Bowel Disease that left him physically emaciated, mentally depleted, and emotionally fragmented. In desperation, he found that a ketogenic diet put his disease into remission where conventional approaches had failed. Fast forward: Nick is now completing the last months of his dual doctorate, with a distinctive determination to upset the intellectual and social environment with respect to metabolic health.Special Thanks to our Episode Sponsors* Genova Connect, powered by Genova Diagnostics - Receive 15% off any of their tests with code METABOLICLINK here* Fatty 15 - Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK here* Timeline - Receive 10% off your first order of Mitopure. Use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

More than a billion people around the world suffer from mental and neurological disorders, and the numbers are escalating rapidly. Current treatments often fail to provide relief, resulting in many patients struggling with persistent symptoms and resistance to available therapies.In this episode, we're sharing a full presentation by world-renowned Harvard Psychiatrist, Dr. Christopher Palmer, filmed at Metabolic Health Summit 2024. Dr. Palmer presents a novel perspective that examines the potential link between metabolic dysfunction and mental illness. His theory, Brain Energy, proposes that metabolic dysfunction may serve as a unifying mechanism underlying various mental health conditions.Key highlights from this episode include: A dive into the surge in prevalence of mental disorders such as autism, ADHD, and depressionCurrent limitations and challenges within traditional treatment optionsEmerging evidence suggesting metabolic dysfunction as a potential root cause of mental illnessesThe role of the ketogenic diet and other innovative treatmentJoin us for an insightful exploration with Dr. Palmer as we examine how metabolism could reshape our understanding and treatment of mental health conditions.About Dr. Chris PalmerDr. Christopher M. Palmer is a Harvard psychiatrist and researcher working at the interface of metabolism and mental health. He is the Founder and Director of the Metabolic and Mental Health Program and the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an Assistant Professor of Psychiatry at Harvard Medical School. For almost 30 years, he has held administrative, educational, research, and clinical roles in psychiatry at McLean and Harvard. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research in this area, treating patients, writing, and speaking around the world on this topic. Most recently, he has proposed that mental disorders can be understood as metabolic disorders affecting the brain, which has received widespread recognition in both national and international media outlets.Special Thanks to our Episode Sponsors: Genova Connect, powered by Genova Diagnostics: Receive 15% off any of their tests with code METABOLICLINK here.AirDoctor: Receive up to $300 off select air purifiers with code METABOLICLINK here.Timeline: Receive 10% off your first order of Mitopure. Use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here!In this enlightening episode of The Metabolic Link, Dr. Dominic D'Agostino sits down with Dr. Mary Newport to delve into the world of Alzheimer's disease, discussing her pioneering work with ketogenic metabolic therapy. Dr. Newport shares her personal and inspiring journey with her husband, Steve, whose battle with early-onset Alzheimer's led her to discover the life-changing effects of MCT and coconut oil. Dr. Newport also explores the crucial role of nutrition in managing Alzheimer's, the potential of exogenous ketones, and the intriguing hypothesis that links infections to the disease.About Mary Newport:Dr. Mary Newport, M.D., is a seasoned pediatrician and neonatologist with over thirty years of experience. She has been involved in founding and directing neonatal intensive care units in the Tampa Bay area. Transitioning later in her career to home hospice care and health risk assessments, Dr. Newport witnessed firsthand the transformative effects of a ketogenic nutritional intervention using coconut and medium-chain triglyceride oil on her husband, who had early-onset Alzheimer's disease. She has since become an internationally recognized author and speaker, advocating for ketones as a brain fuel alternative.Two recent papers by Dr. Newport:Ketogenic  Strategies for Alzheimer's Disease and Other Memory Impairments: History, Rationale, and 288 Caregiver Case ReportsThe Lipid–Heart Hypothesis and the Keys Equation Defined the Dietary Guidelines but Ignored the Impact of Trans-Fat and High Linoleic Acid ConsumptionSpecial thanks to the sponsors of this episode:Genova Connect, powered by Genova Diagnostics is giving you 15% off any of their tests with code metaboliclink here. Fatty15 is offering you 15% off their 90-day subscription Starter Kit by going visiting this link and using code METABOLICLINK.Timeline is offering 10% off your first order of Mitopure. Visit this link & use code METABOLICLINKIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative for ad-free episodes and CMEsIn this episode of The Metabolic Link, host Victoria Field interviews Dr. Deanna Kelly, a distinguished professor of psychiatry at the University of Maryland School of Medicine. Dr. Kelly is pioneering nutritional interventions to treat serious mental illness and led a groundbreaking trial on the ketogenic diet for schizophrenia, the only inpatient study of its kind in the U.S. Unfortunately, this privately funded trial was recently shut down by the Maryland Department of Health. This interview was recorded before this development.Despite this setback, Dr. Kelly's insights into metabolic therapies offer new pathways for treating serious mental illness. They discuss the impact of diet on mental health, metabolic dysfunction in mental illness, and personalized medicine. Plus, learn how you can support ongoing research by signing a petition organized by Dr. Chris Palmer to reinstate Dr. Kelly's ketogenic diet trial.Sign the Petition hereAbout Dr. Kelly: Deanna L. Kelly, Pharm.D., BCPP, is a Professor of Psychiatry at the University of Maryland School of Medicine and an Affiliate Professor in the School of Pharmacy. She directs the Treatment Research Program at the Maryland Psychiatric Research Center and has been Acting Director since January 2022. An expert in schizophrenia and psychopharmacology, she has published over 235 peer-reviewed articles, coauthored 19 books and chapters, and received the Maltz Prize for her work on gluten and mental health.Special thanks to the sponsors of this episode: Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclinkFatty15 is the first, science-backed, patented C15:0 supplement. Get 15% off their 90-day subscription Starter Kit by going to fatty15.com/METABOLICLINK and using code METABOLICLINK.AirDoctor is an air purifier that filters out 99.99% of dangerous contaminants. Visit airdoctorpro.com and use promo code METABOLICLINK to get up to $300 off select air purifiers!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs: https://membership.metabolicinitiative.comIn this episode of the Metabolic Link Podcast, host Dr. Dom D'Agostino sits down with Dr. Robert Lustig to discuss groundbreaking research unifying different models of obesity. They dive deep into the flaws of the traditional energy balance and carbohydrate-insulin models and introduce a compelling integrative theory encompassing the impact of obesogens, redox biology, and reactive oxygen species (ROS) on metabolic health. The conversation navigates through a review article by Dr. Lustig and others on obesogens from the International Journal of Obesity, dissecting specific obesogens like bisphenol A, phthalates, and glyphosate, and examining how different foods and lifestyle choices can mitigate their effects. This episode is a must-listen for anyone interested in nutritional science, metabolic health, and the future of obesity research.About Dr. LustigRobert H. Lustig, M.D., M.S.L. is Emeritus Professor of Pediatrics in the Division of Endocrinology, and Member of the Institute for Health Policy Studies at UCSF. Dr. Lustig is a neuroendocrinologist, with expertise in metabolism, obesity, and nutrition.To learn more about Dr. Lustig, please visit: https://robertlustig.comSpecial thanks to our sponsors:Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclinkLMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at https://drinklmnt.com/metaboliclinkAquaTru is a reverse osmosis water purifier that uses a 4-stage purification process. Their countertop purifiers work with NO installation and remove 83 dangerous contaminents. Get 20% OFF any AquaTru purifier by using the code METABOLICLINK at AquaTru.comReferenced Papers:Obesogens: a unifying theory for the global rise in obesityDo We Need a New Unifying Theory for Obesity?In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs: https://membership.metabolicinitiative.comIn this interview, host Victoria Field sits down with Dr. Casey Means, a Stanford-trained physician, entrepreneur, and New York Times bestselling author of the new book Good Energy. Dr. Means shares her inspiring journey from being a head and neck surgeon to leaving traditional medicine and becoming a leading voice in the metabolic health field. They take a deep dive into the environmental factors that impact our metabolism, the importance of taking care of your mitochondria, and practical steps to improve your overall metabolic health and well-being. Dr. Means also shares her own health struggles along the way and even sheds light on the emotional aspects of metabolic health, including the importance of navigating through trauma and making peace with death. Tune in for a conversation that is both informative and deeply personal.Casey Means, MD is a Stanford-trained physician and co-founder of Levels, a health technology company with the mission of reversing the world's metabolic health crisis and author of the #1 New York Times bestselling book Good Energy, released May 2024. She received her BA with honors and MD from Stanford, was President of her Stanford class, and has served on Stanford faculty. She trained in Head & Neck Surgery before leaving traditional medicine to devote her life to tackling the root cause of why Americans are sick. She has been featured in The New York Times, The New Yorker, The Wall Street Journal, Forbes, Women's Health, and more. To learn more about Dr. Means, to join her newsletter, and get her book, please visit: https://www.caseymeans.com/Special thanks to our sponsors:Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclinkLMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at https://drinklmnt.com/metaboliclink AirDoctor is an air purifier that filters out 99.99% of dangerous contaminants so your lungs don't have to. Visit airdoctorpro.com and used promo code METABOLIC LINK to get UP TO $300 ofIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs! Registered dietitian, Lily Nichols, RDN, CDE, is back on The Metabolic Link, this time in an intimate interview that dives into the critical links between metabolic health, perinatal nutrition, and long-term wellbeing. This episode dives deep into how nutrition during the childbearing years can affect not only mothers but their children throughout their lives.Lily, who is also a New York Times bestselling author of key books on prenatal nutrition, unpacks the significance of blood sugar balance, the role of various micronutrients, and the timing and composition of meals in optimizing fertility and pregnancy health. She shares her expertise on managing gestational diabetes through dietary adjustments and explains how both maternal and paternal health can influence pregnancy outcomes. Additionally, the conversation includes discussions around fertility treatments and assisted reproductive technologies.About Lily Nichols, RDN, CDE:Lily Nichols is a Registered Dietitian/Nutritionist, Certified Diabetes Educator, researcher, and author with a passion for evidence-based nutrition. She is the founder of the Institute for Prenatal Nutrition®, co-founder of the Women's Health Nutrition Academy, and the author of three books: Real Food for Fertility, Real Food for Pregnancy, and Real Food for Gestational Diabetes.We're hosting a Live Q&A with Lily Nichols as a follow up to this episode on June 12th at 8am PT/11am ET! Bring your questions and join our medical education platform with a FREE 7-day free trial. Click here to register. Special thanks to our sponsors:Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclink LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at https://drinklmnt.com/metaboliclinkTimeline, a Swiss based life science company, is a global leader in Urolithin A research. Timeline is offering 10% off your first order of Mitopure. Go to timeline.com/METABOLICLINK & use code METABOLICLINKIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs!Join us in this enlightening episode as we dive deep into the emerging research behind Urolithin A and its impact on mitochondrial health with Dr. Anurag Singh, a leading expert in the field and the Chief Medical Officer of Timeline.The discussion spans various facets of Urolithin A, from its origin in pomegranates and other foods to its potential in improving mitochondrial health, muscle strength, and reducing inflammation. Dr. Singh shares insights from his decade-long research on this remarkable compound, discussing everything from the science of mitophagy to its implications for overall health. You'll also hear about the synergistic effects of combining Urolithin A with other mitochondrial-targeting compounds and therapies like ketogenic diets and exogenous ketones.The episode also reveals fascinating findings on how Urolithin A interacts with our cellular machinery to combat age-related decline and offers a peek into future applications, including a unique perspective on transdermal delivery systems. Dr. Singh's expert knowledge sheds light on the exciting future directions of Urolithin A research and its vast potential applications.About Dr. Anurag Singh:Dr. Anurag Singh is currently the Chief Medical Officer at Timeline, a company that develops next-generation advanced nutritional products targeting improvements in mitochondrial and muscle health. With an M.D. in internal medicine and a Ph.D. in immunology, his experience includes work for top consumer health and startup/biotech companies. He's authored more than 40 articles in top science journals and has designed and led more than 50 randomized clinical trials in nutrition.Learn more about Timeline and Mitopure. Special thanks to our sponsors of this episode:Genova Connect, powered by Genova Diagnostics offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Receive 15% off any of their tests with code metaboliclink at https://gdx.net/themetaboliclinkLMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at https://drinkLMNT.coIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative for exclusive episodes and earn CMEs! Dive into the core of nutrition science with Dr. Dominic D'Agostino and Dr. Nina Teicholz, and uncover the remarkable benefits of saturated fats, unravel the complexities of LDL cholesterol, and dig into the heated debate surrounding food addiction and ethical meat consumption. Dr. Teicholz sheds light on the misunderstood facets of dietary fats, debunking prevalent myths about cholesterol, highlighting potential detrimental effects of seed oils, and offering profound insights into how adherence to outdated dietary guidelines impacts both our health and the environment. Bring your follow up questions on May 16th at 1pm PT/4pm ET to our Live Q&A with Dr. Teicholz on our medical education platform, The Metabolic Initiative. Your first 7 days on the platform are free! Visit this link to register. To access Dr. Sarah Hallberg's legacy course, please click here. More info on Dr. Teicholz and her latest articles, click here. Thank you to our sponsors of this episode: Genova Connect, powered by Genova Diagnostics offers advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Receive 15% off any of their tests with code metaboliclink: https://gdx.net/themetaboliclink LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at: https://drinkLMNT.com/MetabolicLink In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Become a member of The Metabolic Initiative for exclusive episodes and to earn CMEsIn this episode, recorded at Metabolic Health Summit 2024, Dr. Richard Johnson dives into the groundbreaking research that has uncovered the central role of fructose in driving the epidemics of obesity, diabetes, and a wide range of other metabolic diseases.Dr. Johnson presents compelling evidence that fructose, a seemingly innocuous sugar, is in fact a key trigger for activating a powerful biological survival switch. This switch, evolved in nature to help animals prepare for times of scarcity, is now being inadvertently activated in humans by our modern high-carbohydrate, high-sugar diets.Through detailed scientific explanation and insightful case studies, Dr. Johnson illuminates how fructose's unique metabolic effects - including its ability to lower ATP levels, induce leptin resistance, and promote fat storage - are the driving forces behind the rise of metabolic syndrome and its associated conditions.Equally important, Dr. Johnson offers practical dietary recommendations and strategies to help individuals navigate this complex landscape, emphasizing the importance of reducing sugar, refined carbs, and processed foods, while embracing a low-carb, nutrient-dense approach.This eye-opening episode is a must-listen for anyone seeking to understand the root causes of the metabolic health crisis and learn evidence-based solutions to reclaim their wellbeing.Special thanks to our sponsors:Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Receive 15% off any of their tests with code metaboliclink: http://gdx.net/themetaboliclink LMNT, a zero-sugar electrolyte drink mix free of artificial colors and dodgy ingredients. Get a free LMNT Sample Pack with any drink mix purchase at: drinkLMNT.com/MetabolicLink In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode of The Metabolic Link, Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff dive into a fascinating new paper that compares the metabolic and immune impacts of ketogenic and vegan diets in humans.The study, titled “Differential Peripheral Immune Signatures Elicited by Vegan Versus Ketogenic Diets in Humans” takes a deep dive into the multi-omic effects of these two very different dietary approaches. The researchers found that just two weeks on a ketogenic diet significantly enhanced markers of adaptive immunity, while the vegan diet was associated with increased innate immune function.The hosts unpack these findings, discussing the potential mechanisms behind the divergent immune signatures, the limitations of the short-term study design, and the need for further research.They also highlight the importance of carefully standardizing the macronutrient and micronutrient compositions of the dietary interventions to isolate the key drivers of the observed changes.Overall, this episode provides a thought-provoking look at the profound impacts that diet can have on the functioning of our immune system, setting the stage for future studies exploring the therapeutic potential of nutritional approaches.This episode is sponsored by Genova Diagnostics. Genova has been researching and refining precision health testing for decades. It's that experience that has allowed them to create comprehensive assessments that shed light on your individual health status and make recommendations for changes that will bring your wellness into focus.Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Through Genova Connect, anyone can gain insights into their health and find ways to improve their well-being. Learn more at https://gdx.net/themetaboliclinkAs mentioned in the introduction, you can watch the free virtual masterclass co-hosted Genova Diagnostics and Metabolic Health Summit showcasing some of the world-leading experts in metabolic health hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

The following Metabolic Link episode was originally filmed at Metabolic Health Summit 2024 and we're excited to share it with you today in its entirety! In this presentation, Dr. Andy Galpin, a human performance scientist, shares his insights on utilizing scientific principles, specifically the 'Biomolecular Athlete' concept, to achieve athletic excellence. He emphasizes the importance of individualized strategies that consider sleep, diet, stress, respiratory rates, and blood chemistry.The discussion then progresses to the groundbreaking future of human performance, including the use of digital twins for simulating and optimizing individual health outcomes, and the exploration of advanced technologies such as in-mouth sensors, full-body MRI, shoe sole force plates, and markerless motion capture.Case studies are presented to illustrate the successful application of these innovative approaches, showcasing the potential for precision and customization in coaching for optimal health and performance.This talk is sponsored by Genova Diagnostics. Genova has been researching and refining precision health testing for decades. It's that experience that has allowed them to create comprehensive assessments that shed light on your individual health status and make recommendations for changes that will bring your wellness into focus.Genova Connect, powered by Genova Diagnostics, offers easy access to advanced lab tests, covering key health areas like metabolic health, nutrition, gut health, immune function, and hormones. Through Genova Connect, anyone can gain insights into their health and find ways to improve their well-being. Learn more at gdx.net/themetaboliclinkAs mentioned in the introduction, you can watch this free virtual masterclass co-hosted Genova Diagnostics and Metabolic Health Summit showcasing some of the world-leading experts in metabolic health.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an illuminating sit-down interview with Dr. Jeff Volek, a professor at The Ohio State University. With a PhD in Kinesiology specializing in exercise and nutrition science from Penn State University, Dr. Volek has performed cutting edge research on how humans adapt to diets restricted in carbohydrates with a dual focus on clinical and performance applications of nutritional ketosis. His scholarly work includes more than 300 peer-reviewed scientific manuscripts and five books, including a New York Times Best Seller.In this wide-ranging interview, we cover:

This week's episode of The Metabolic Link features a full presentation from Metabolic Health Summit 2024. Dr. Ben Bikman, professor at Brigham Young University, dives deep into the intricacies of fat and its relationship to metabolic health.This is the full presentation he delivered at Metabolic Health Summit 2024 in Clearwater Beach, Florida. In it he shares his expertise on the link between body fat, insulin resistance, and chronic diseases such as obesity and diabetes. Throughout this talk, he covers:

This week's episode of The Metabolic Link features an illuminating sit-down interview with Dr. Georgia Ede, a Harvard-trained psychiatrist specializing in nutrition science and brain metabolism. With over 25 years of clinical experience, including 12 years as a college psychiatrist and nutrition consultant at Smith College and Harvard University Health Services, Dr. Ede was the first to offer students nutrition-based approaches as an alternative to psychiatric medications. She speaks internationally about using dietary therapies for psychiatric disorders, co-authored the first inpatient study of the ketogenic diet for treatment-resistant mental illness, and developed the first accredited course on ketogenic diets for mental health practitioners. Her new book Change Your Diet, Change Your Mind was published in January 2024.In this wide-ranging interview, we cover:Implementing a therapeutic ketogenic diet in Dr. Ede's clinical practice and the mental health benefits observedThe critical role of ketones in alleviating cerebral glucose hypometabolismWhy metabolic health forms the foundation for optimal mental healthThe lack of practical nutrition education in medical training and why it mattersAlzheimer's disease as a metabolic disorderThe importance of insulin levels, not just glucose, for gauging metabolic healthWatch the full episode on our Metabolic Health Summit YouTube channel and be sure to catch Dr. Ede on The Metabolic Psychiatry Panel featuring Dr. Chris Palmer, Dr. Iain Campbell, and Matt Baszucki. On-Demand access closes on Friday, February 16th so don't wait! Get your virtual pass at metabolichealthsummit.com.Also be sure to catch Dr. Ede on March 6th where she'll be joining us for a live Q&A on The Metabolic Initiative. We'll be exploring ketogenic therapy for mental health. Register to join us here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode of The Metabolic Link, Dr. Dominic D'Agostino, Dr. Angela Poff, and Victoria Field recap Metabolic Health Summit 2024, the world's leading medical and scientific conference on metabolic health. Listen to this episode to get an inside look at the top scientific highlights and surprising moments from the perspective of the hosts who made it happen.Want to learn about all the cutting-edge research and scientific insights on metabolic health and therapy that you won't find anywhere else? We recorded the entirety of Metabolic Health Summit 2024 and you can still watch the replay, but the window is closing very soon! Click here to secure your access before time runs out.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

We've just launched an extra and exciting episode of The Metabolic Link podcast! It features an eye-opening conversation between our host Dominic D'Agostino PhD, and guests Dave Feldman and Dr. Nick Norwitz, two researchers and MHS 2024 speakers spearheading investigations into the lean mass hyperresponder (LMHR) phenotype.Dave Feldman is a software engineer who became deeply interested in lipidology after seeing his cholesterol spike on a low-carb, high-fat diet. He has since performed self-experiments and published several papers on the possible mechanisms behind LMHR. He is currently conducting a clinical study out of UCLA through his newly formed public charity, the Citizen Science Foundation.Nicholas Norwitz completed his PhD at the University of Oxford and his thesis focused on ketone metabolism and neurodegenerative diseases. He is currently a medical student at Harvard Medical School.In this episode Dave, Dr. Norwitz, and Dr. D'Agostino dive into…The debate around whether saturated fat drives increased LDL levels, especially in the LMHR phenotype.The "Lipid Energy Model" hypothesizing a metabolic/physiological process underlying LMHR phenotype. Concerns about erroneously grouping lean mass hyperresponders with familial hypercholesterolemia patients. The importance of separating discussions of underlying mechanism from clinical recommendations.Their vision for the future direction of LMHR research and public education on this topic.Be sure to secure your spot at MHS 2024 in Clearwater Beach, Florida, where Dave and Nick will be presenting their latest research! Both virtual and in-person seats are still available at metabolichealthsummit.com.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an illuminating conversation between our host Dr. Dominic D'Agostino and Dr. Jonathan Jun, a pulmonary critical care and sleep medicine physician at Johns Hopkins.He is an expert in the diagnosis and treatment of sleep-disordered breathing, and in the care of critically ill patients in the Medical ICU. He is a member of the Sleep Fellowship Program Evaluation and Clinical Competency Committee and provides teaching to medical students and residents at Johns Hopkins.In this episode, we cover:

In this episode, our co-hosts Dr. Dominic D'Agostino, Dr. Angela Poff, and Victoria Field discuss two recent scientific papers on the metabolic effects of allulose and how blocking fructose intake may help fight cancer.The first paper examines how allulose consumption influences metabolic factors like appetite, blood sugar, and insulin sensitivity through the release of key gut hormones and effects on carbohydrate digestion and metabolism.The second paper reviews multiple lines of evidence linking fructose metabolism to driving cancer progression. High fructose intake may directly supply tumors with fuel and biomolecular building blocks to grow while also creating an obesity and diabetic state that triggers cancer development. The paper proposes dietary fructose restriction as a potential anti-cancer intervention.Overall, the episode illuminates cutting-edge research on sugar, diet and disease. With that said, our hosts emphasize the need for further study. In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an illuminating conversation between our host Dr. Dom D'Agostino and Chad Vanags, a successful entrepreneur who is navigating a stage 4 cancer diagnosis with courage and purpose.After being diagnosed with stage 4 lung cancer in 2022 at just 39 years old, Chad has been documenting his journey to becoming “metabolically, physically, and mentally elite” to continue pursuing his life's vision.In this wide-ranging discussion, we cover:

This week's episode of The Metabolic Link features an illuminating conversation between our host Dominic D'Agostino, PhD, and Franziska Spritzler, RD, CDE.Franziska is a registered dietitian and certified diabetes educator who specializes in low-carb and ketogenic diets. She has been following a low-carb approach for over a decade.In this episode, we cover:

In this episode, our co-hosts Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff discuss two recent scientific papers on the potential metabolic connections to psychiatric disorders and mindfulness-based interventions.The first paper is a systematic review on the efficacy of low-carb and ketogenic diets for treating mood and anxiety disorders. They discuss the importance in defining what constitutes a low-carb or ketogenic diet in research studies. Our hosts also discuss the limited data available, with only 12 studies meeting the criteria for inclusion. However, the review indicates some positive preliminary findings for the use of these diets for conditions like bipolar disorder, depression and schizophrenia.The second paper is a meta-analysis examining mindfulness-based interventions for psychiatric disorders. It found mindfulness approaches were superior to non-evidence based treatments and comparable to standard therapies for conditions like anxiety and depression. Our hosts discuss the need for more research, but note the promising potential for simple lifestyle approaches like mindfulness, breathwork and nutrition to positively impact mental health.Overall, the episode highlights emerging science linking metabolic function to brain health and psychiatric wellbeing. Our hosts emphasize the need to continue conducting rigorous clinical trials in this nascent field of metabolic psychiatry and share their perspectives on implementing lifestyle interventions for optimal mental health.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an illuminating conversation between our host Dr. Dominic D'Agostino and Dr. Kyle Gillett, a board-certified physician in family and obesity medicine who provides holistic care to his patients.He earned his medical degree at the University of Kansas School of Medicine, practices at the Gillett Health Clinic in Olathe, Kansas, and is the host of The Gillett Health Podcast. His practice focuses on preventive, integrative, and precision medicine approaches, with expertise in hormone and metabolic optimization.In this wide-ranging discussion, we cover:Using genotyping and pharmacogenomics to guide personalized medicineAssessing the impact of environmental contaminants versus diet on metabolic healthThe lean mass hyper responder phenotype that some experience on ketogenic dietsPerspectives on non-nutritive sweeteners and emerging research on alluloseTailoring exercise plans as medicine for each patient's needs and goalsOptimizing sleep, sunlight, and stress - key for shift workersThe importance of cultivating emotional wellness for overall healthDon't miss Dr. Gillett's talk at Metabolic Health Summit 2024! Register now before spots sell out at MetabolicHealthSummit.com.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an eye-opening discussion between Metabolic Health Summit organizer Victoria Field and prenatal nutrition expert Lily Nichols, RDN, CDE. Lily is the author of two bestselling books - Real Food for Pregnancy and Real Food for Gestational Diabetes. Her work focuses on evidence-based, critical analysis of conventional pregnancy nutrition recommendations.In this episode, we cover:Evaluating macronutrient needs in pregnancy, including research suggesting carbohydrate intake recommendations may be set too high, and protein intake targets too lowThe use of nutritional ketosis in pregnancyThe latest research on preventing gestational diabetes and preeclampsia through dietHow to eat for a healthy postpartum recovery - it's about way more than breastfeeding!The fascinating science of how prenatal nutrition impacts gene expression in babiesLily shares paradigm-shifting insights from her clinical experience and extensive research. Her balanced approach debunks outdated advice while offering practical solutions. Expect an illuminating conversation that will change how you think about nourishing yourself and your future baby!Don't miss Lily's talk at the Metabolic Health Summit 2024 in Clearwater Beach, Florida! Register now before spots sell out at metabolichealthsummit.com.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this week's episode of The Metabolic Link, double board certified psychiatrist and obesity medicine physician, Dr. Shebani Sethi, takes us on a deep dive into the emerging field of metabolic psychiatry.Dr. Shebani Sethi is a psychiatrist and obesity medicine physician at Stanford University School of Medicine. She is the founding director of the Stanford Metabolic Psychiatry Clinic, where she researches dietary and pharmacological interventions to improve metabolic health and mental illness. Her background and expertise in integrating low carbohydrate nutrition with psychiatric care has created the foundation for Dr. Sethi to effectively treat patients based on the link between metabolism and brain function.In this episode filmed in May 2022, we cover:How Dr. Sethi implements metabolic therapy like ketogenic diets to improve psychiatric symptoms in patientsDetails on her clinical research, including a pilot study on ketogenic diets for schizophrenia and bipolar disorderUsing ketosis for 15+ years to treat conditions like depressionHopes for metabolic psychiatry concepts to spread and integrated care to become more accessibleFuture studies examining fMRI brain imaging on ketogenic dietsIf you're interested in learning more about the body-brain connection and how metabolic dysfunction relates to mental illness, you won't want to miss this episode!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an illuminating conversation between our host Dominic D'Agostino, PhD, and Dr. Abbi Hernandez, an assistant professor at the University of Alabama at Birmingham.Dr. Hernandez received her PhD from the University of Florida, where she studied age and diet related changes in neurological function and cognitive health. Her research has focused on investigating the potential of ketogenic diets and time-restricted feeding for preventing age-related cognitive decline. Recently, she has been exploring the gut-brain axis.In this episode, we cover:The importance of the hippocampus for learning, memory, and cognitionInnovative rodent behavioral tests used to identify age-related cognitive impairmentsMetabolic flexibility in the aging brain and the role of ketonesHow time-restricted feeding alters the gut microbiome and cognitive performanceFuture research directions on alternative brain fuels like lactateExploring the possibility of using probiotics to mimic the effects of ketosis on the brainDr. Hernandez will also be a speaker at Metabolic Health Summit 2024! Secure your spot here! Early bird pricing runs through October 1st and then it's gone for good!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this week's episode, host Victoria Field speaks with Matt Baszucki and Dr. Iain Campbell about their lived experiences with bipolar disorder and the therapeutic effects of the ketogenic diet, potential root causes of the mental illness, and their mission to spread awareness and education around ketogenic dietary therapy as a treatment for bipolar disorder.Iain Campbell, PhD, is the Baszucki Research Fellow in Metabolic Psychiatry at the University of Edinburgh. He has a PhD in Global Health from the University of Edinburgh and is a principal investigator on a pilot trial of a ketogenic diet for bipolar disorder.Matt Baszucki lived with type 1 bipolar disorder for five years before coming across ketogenic therapy, and now works to educate the public about the roles of sleep, diet, and circadian rhythm management in mental illness. He currently works full-time in tech supporting third-party developers. Together, Matt and Iain host the BipolarCast podcast which can be found on YouTube. You can also learn more about the Baszucki Brain Research Fund here and watch Metabolic Mind's YouTube channel here. In this episode, we cover:Iain's and Matt's personal lived experiences with bipolar disorder & success in using ketogenic dietary therapyDr. Campbell's current research on the effectiveness of the ketogenic diet for bipolar disorderBipolar disorder as an “energy-specific disorder” and its potential connection to metabolic dysregulationThe many ways people can adapt their keto diet to meet their needs and lifestyle…and so much more.Matt Baszucki and Dr. Iain Campbell will also be speaking at Metabolic Health Summit 2024, January 25-28 in Clearwater, Florida - you can get your tickets on the Metabolic Health Summit website and save with Early Bird pricing through October 1st, 2023!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode, our co-hosts Victoria Field, Dominic D'Agostino, PhD, and Angela Poff, PhD, discuss two recent scientific studies that focus on the potential metabolic connections to neurodegenerative diseases.Study 1: Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's diseaseThe study delves into the molecular changes causing a neuron's transition from healthy to degenerative, as seen in sporadic Alzheimer's, which is the most prevalent form of Alzheimer's disease and isn't directly inherited but arises from a mix of genetic and environmental factors. It proposes that metabolic changes in neurons due to altered gene expression might play a role in the disease's onset. Today's discussion touches upon the similarities between the findings in this study and the well-established Warburg Effect seen in cancer. This study may provide a clue to the molecular mechanisms behind Alzheimer's disease and open the door for exploration of potential treatments.Study 2: Phase II study of ketogenic diets in relapsing multiple sclerosis: safety, tolerability, and potential clinical benefitsThis study measured the impact of a dietitian-guided ketogenic diet on MS patients on several markers including body composition, mood, mental health, and physical stamina. Our co-hosts discuss these findings as well as the secondary benefits of ketogenic therapies due to reduced MS symptoms, and the unique challenges of dietary vs pharmaceutical trials, such as ensuring accuracy, participant compliance and how to measure the intervention's effectiveness.If you'd like to read the papers referenced above, please find them here: Study 1 & Study 2In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an in-depth conversation between our host Dominic D'Agostino, PhD, and Jeff Volek, PhD, RD, on a wide range of topics as well as questions submitted by our Twitter followers!Dr. Volek is a registered dietitian and professor in the Department of Human Sciences at The Ohio State University. For the last 25 years, he has performed translational research on how humans adapt to ketogenic diets with a dual focus on clinical and performance applications of nutritional ketosis.In this episode, we cover:Dr. Volek's mentors and academic highlightsSupplementary compounds for ketosis including MCT oil and exogenous ketonesThe much-debated discussions surrounding LDL levels, bone density and kidney function while on the ketogenic dietNew developments in keto researchDr. Jeff Volek will also be a speaker at Metabolic Health Summit 2024 - Early Bird pricing ends August 1st! Secure your spot at metabolichealthsummit.com!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

On this week's episode of The Metabolic Link, our host and MHS Co-organizer Victoria Field interviewed Kelly Faltersack, a registered dietitian nutritionist, who specializes in treating patients with ketogenic diet therapy as an effective treatment for epilepsy and other neurological disorders.Kelly Faltersack MS, RDN, LDN, CD is a registered dietitian nutritionist at UW Health in Madison, Wisconsin. Kelly has over 10 years of experience as a registered dietitian nutritionist, and five years of experience in neuro intensive care. She has specialized in ketogenic metabolic therapy for adults with epilepsy and other neurological conditions since 2016. Kelly has co-authored publications on ketogenic metabolic therapy and serves on the medical advisory board for the Glut1 Deficiency Foundation.This episode is chock-full of resources and tips from Kelly, and her passion for improving the health of her patients is evident.In this episode, we cover:Kelly's personal experience with the healing potential of diet and nutritionThe benefits of ketogenic diet therapy for epilepsy and other neurological disordersHow to tailor the ketogenic diet to be sustainable for your patients' lifestyleThe discrepancy between available ketogenic therapies for children with epilepsy vs adultsKelly Faltersack will be a speaker at Metabolic Health Summit 2024 held in Clearwater Beach, Florida from January 25th - 28th! To register and save with Early Bird Pricing through August 1st, please visit: https://metabolichealthsummit.com/pages/mhs2024In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This week's episode of The Metabolic Link features an enlightening conversation between our host Dr. Dominic D'Agostino and Dr. Satchin Panda, PhD on the fascinating connection between time-restricted eating, circadian rhythm, and metabolic health. A leading expert in the field of circadian rhythm research, Dr. Panda is a professor at the Salk Institute for Biological Studies and a founding executive member of the Center for Circadian Biology at the University of California.Have you been hearing lately about the importance of morning light exposure?Well, you have Dr. Satchin Panda's research to thank for that. His research discovered that melanopsin cells in our retinas detect sunlight and send signals to our pineal gland - ultimately regulating the release of melatonin and other neurotransmitters responsible for the natural timing of circadian rhythms.And just as metabolic health is inextricably linked to most, if not all, biological processes in the human body, Dr. Panda's work explores the genes, molecules and cells that keep the whole body on the circadian clock.In this episode, we cover:Research contrasting the effects of time-restricted eating vs. calorie-restriction for weight loss and metabolic health biomarkersThe benefits and sustainability of time-restriction vs. calorie-restriction for the average patientMelatonin's role in both circadian rhythm and metabolic function…and 3 things anyone can do to optimize their circadian biologyIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel, Apple, Google, Spotify, Amazon Music, and Buzzsprout.Thanks for listening! Follow us on social media @metabolichealthsummit for the latest science on metabolic health and therapy. Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.