Podcasts about Braunstein

In My Tax Dollars: The Morality of Taxpaying in America (Princeton University Press, 2025), Ruth Braunstein maps the contested moral landscape in which Americans experience and make sense of the tax system. Braunstein tells the stories of Americans who view taxpaying as more than a mundane chore: antigovernment tax defiers who challenge the legitimacy of the tax system, antiwar activists who resist the use of their taxes to fund war, antiabortion activists against “taxpayer funded abortions,” and a diverse group of people who promote taxpaying as a moral good. Though taxpaying is often portrayed as dull and technical, exposure to collective rituals, civic education, propaganda, and protest transforms the practice for many Americans into either a sacred rite of citizenship or a profane threat to what they hold dear. These sacred and profane meanings can apply to the act of taxpaying itself or to the specific uses of tax dollars. Despite intense disagreement about these meanings, politically diverse Americans engaged in both taxpaying and tax resistance valorize the individual taxpayer and “my tax dollars.”Braunstein explores the profound implications of this meaning making for tax consent, the legitimacy of the tax system, and citizens' broader understandings of their political relationships. Going beyond the usual focus on tax policy, Braunstein's innovative view of taxation through the lens of cultural sociology shows how citizens in value-diverse societies coalesce around shared visions of the sacred and fears of the profane. Interviewee: Ruth Braunstein is Associate Professor of sociology at the University of Connecticut. Host: Schneur Zalman Newfield is an Associate Professor of Sociology and Jewish Studies at Hunter College, City University of New York, and the author of Degrees of Separation: Identity Formation While Leaving Ultra-Orthodox Judaism (Temple University Press). Visit him online at ZalmanNewfield.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/american-studies

In My Tax Dollars: The Morality of Taxpaying in America (Princeton University Press, 2025), Ruth Braunstein maps the contested moral landscape in which Americans experience and make sense of the tax system. Braunstein tells the stories of Americans who view taxpaying as more than a mundane chore: antigovernment tax defiers who challenge the legitimacy of the tax system, antiwar activists who resist the use of their taxes to fund war, antiabortion activists against “taxpayer funded abortions,” and a diverse group of people who promote taxpaying as a moral good. Though taxpaying is often portrayed as dull and technical, exposure to collective rituals, civic education, propaganda, and protest transforms the practice for many Americans into either a sacred rite of citizenship or a profane threat to what they hold dear. These sacred and profane meanings can apply to the act of taxpaying itself or to the specific uses of tax dollars. Despite intense disagreement about these meanings, politically diverse Americans engaged in both taxpaying and tax resistance valorize the individual taxpayer and “my tax dollars.”Braunstein explores the profound implications of this meaning making for tax consent, the legitimacy of the tax system, and citizens' broader understandings of their political relationships. Going beyond the usual focus on tax policy, Braunstein's innovative view of taxation through the lens of cultural sociology shows how citizens in value-diverse societies coalesce around shared visions of the sacred and fears of the profane. Interviewee: Ruth Braunstein is Associate Professor of sociology at the University of Connecticut. Host: Schneur Zalman Newfield is an Associate Professor of Sociology and Jewish Studies at Hunter College, City University of New York, and the author of Degrees of Separation: Identity Formation While Leaving Ultra-Orthodox Judaism (Temple University Press). Visit him online at ZalmanNewfield.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/political-science

In My Tax Dollars: The Morality of Taxpaying in America (Princeton University Press, 2025), Ruth Braunstein maps the contested moral landscape in which Americans experience and make sense of the tax system. Braunstein tells the stories of Americans who view taxpaying as more than a mundane chore: antigovernment tax defiers who challenge the legitimacy of the tax system, antiwar activists who resist the use of their taxes to fund war, antiabortion activists against “taxpayer funded abortions,” and a diverse group of people who promote taxpaying as a moral good. Though taxpaying is often portrayed as dull and technical, exposure to collective rituals, civic education, propaganda, and protest transforms the practice for many Americans into either a sacred rite of citizenship or a profane threat to what they hold dear. These sacred and profane meanings can apply to the act of taxpaying itself or to the specific uses of tax dollars. Despite intense disagreement about these meanings, politically diverse Americans engaged in both taxpaying and tax resistance valorize the individual taxpayer and “my tax dollars.”Braunstein explores the profound implications of this meaning making for tax consent, the legitimacy of the tax system, and citizens' broader understandings of their political relationships. Going beyond the usual focus on tax policy, Braunstein's innovative view of taxation through the lens of cultural sociology shows how citizens in value-diverse societies coalesce around shared visions of the sacred and fears of the profane. Interviewee: Ruth Braunstein is Associate Professor of sociology at the University of Connecticut. Host: Schneur Zalman Newfield is an Associate Professor of Sociology and Jewish Studies at Hunter College, City University of New York, and the author of Degrees of Separation: Identity Formation While Leaving Ultra-Orthodox Judaism (Temple University Press). Visit him online at ZalmanNewfield.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

In My Tax Dollars: The Morality of Taxpaying in America (Princeton University Press, 2025), Ruth Braunstein maps the contested moral landscape in which Americans experience and make sense of the tax system. Braunstein tells the stories of Americans who view taxpaying as more than a mundane chore: antigovernment tax defiers who challenge the legitimacy of the tax system, antiwar activists who resist the use of their taxes to fund war, antiabortion activists against “taxpayer funded abortions,” and a diverse group of people who promote taxpaying as a moral good. Though taxpaying is often portrayed as dull and technical, exposure to collective rituals, civic education, propaganda, and protest transforms the practice for many Americans into either a sacred rite of citizenship or a profane threat to what they hold dear. These sacred and profane meanings can apply to the act of taxpaying itself or to the specific uses of tax dollars. Despite intense disagreement about these meanings, politically diverse Americans engaged in both taxpaying and tax resistance valorize the individual taxpayer and “my tax dollars.”Braunstein explores the profound implications of this meaning making for tax consent, the legitimacy of the tax system, and citizens' broader understandings of their political relationships. Going beyond the usual focus on tax policy, Braunstein's innovative view of taxation through the lens of cultural sociology shows how citizens in value-diverse societies coalesce around shared visions of the sacred and fears of the profane. Interviewee: Ruth Braunstein is Associate Professor of sociology at the University of Connecticut. Host: Schneur Zalman Newfield is an Associate Professor of Sociology and Jewish Studies at Hunter College, City University of New York, and the author of Degrees of Separation: Identity Formation While Leaving Ultra-Orthodox Judaism (Temple University Press). Visit him online at ZalmanNewfield.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/sociology

In My Tax Dollars: The Morality of Taxpaying in America (Princeton University Press, 2025), Ruth Braunstein maps the contested moral landscape in which Americans experience and make sense of the tax system. Braunstein tells the stories of Americans who view taxpaying as more than a mundane chore: antigovernment tax defiers who challenge the legitimacy of the tax system, antiwar activists who resist the use of their taxes to fund war, antiabortion activists against “taxpayer funded abortions,” and a diverse group of people who promote taxpaying as a moral good. Though taxpaying is often portrayed as dull and technical, exposure to collective rituals, civic education, propaganda, and protest transforms the practice for many Americans into either a sacred rite of citizenship or a profane threat to what they hold dear. These sacred and profane meanings can apply to the act of taxpaying itself or to the specific uses of tax dollars. Despite intense disagreement about these meanings, politically diverse Americans engaged in both taxpaying and tax resistance valorize the individual taxpayer and “my tax dollars.”Braunstein explores the profound implications of this meaning making for tax consent, the legitimacy of the tax system, and citizens' broader understandings of their political relationships. Going beyond the usual focus on tax policy, Braunstein's innovative view of taxation through the lens of cultural sociology shows how citizens in value-diverse societies coalesce around shared visions of the sacred and fears of the profane. Interviewee: Ruth Braunstein is Associate Professor of sociology at the University of Connecticut. Host: Schneur Zalman Newfield is an Associate Professor of Sociology and Jewish Studies at Hunter College, City University of New York, and the author of Degrees of Separation: Identity Formation While Leaving Ultra-Orthodox Judaism (Temple University Press). Visit him online at ZalmanNewfield.com.

In My Tax Dollars: The Morality of Taxpaying in America (Princeton University Press, 2025), Ruth Braunstein maps the contested moral landscape in which Americans experience and make sense of the tax system. Braunstein tells the stories of Americans who view taxpaying as more than a mundane chore: antigovernment tax defiers who challenge the legitimacy of the tax system, antiwar activists who resist the use of their taxes to fund war, antiabortion activists against “taxpayer funded abortions,” and a diverse group of people who promote taxpaying as a moral good. Though taxpaying is often portrayed as dull and technical, exposure to collective rituals, civic education, propaganda, and protest transforms the practice for many Americans into either a sacred rite of citizenship or a profane threat to what they hold dear. These sacred and profane meanings can apply to the act of taxpaying itself or to the specific uses of tax dollars. Despite intense disagreement about these meanings, politically diverse Americans engaged in both taxpaying and tax resistance valorize the individual taxpayer and “my tax dollars.”Braunstein explores the profound implications of this meaning making for tax consent, the legitimacy of the tax system, and citizens' broader understandings of their political relationships. Going beyond the usual focus on tax policy, Braunstein's innovative view of taxation through the lens of cultural sociology shows how citizens in value-diverse societies coalesce around shared visions of the sacred and fears of the profane. Interviewee: Ruth Braunstein is Associate Professor of sociology at the University of Connecticut. Host: Schneur Zalman Newfield is an Associate Professor of Sociology and Jewish Studies at Hunter College, City University of New York, and the author of Degrees of Separation: Identity Formation While Leaving Ultra-Orthodox Judaism (Temple University Press). Visit him online at ZalmanNewfield.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/public-policy

In My Tax Dollars: The Morality of Taxpaying in America (Princeton University Press, 2025), Ruth Braunstein maps the contested moral landscape in which Americans experience and make sense of the tax system. Braunstein tells the stories of Americans who view taxpaying as more than a mundane chore: antigovernment tax defiers who challenge the legitimacy of the tax system, antiwar activists who resist the use of their taxes to fund war, antiabortion activists against “taxpayer funded abortions,” and a diverse group of people who promote taxpaying as a moral good. Though taxpaying is often portrayed as dull and technical, exposure to collective rituals, civic education, propaganda, and protest transforms the practice for many Americans into either a sacred rite of citizenship or a profane threat to what they hold dear. These sacred and profane meanings can apply to the act of taxpaying itself or to the specific uses of tax dollars. Despite intense disagreement about these meanings, politically diverse Americans engaged in both taxpaying and tax resistance valorize the individual taxpayer and “my tax dollars.”Braunstein explores the profound implications of this meaning making for tax consent, the legitimacy of the tax system, and citizens' broader understandings of their political relationships. Going beyond the usual focus on tax policy, Braunstein's innovative view of taxation through the lens of cultural sociology shows how citizens in value-diverse societies coalesce around shared visions of the sacred and fears of the profane. Interviewee: Ruth Braunstein is Associate Professor of sociology at the University of Connecticut. Host: Schneur Zalman Newfield is an Associate Professor of Sociology and Jewish Studies at Hunter College, City University of New York, and the author of Degrees of Separation: Identity Formation While Leaving Ultra-Orthodox Judaism (Temple University Press). Visit him online at ZalmanNewfield.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/economics

In My Tax Dollars: The Morality of Taxpaying in America (Princeton University Press, 2025), Ruth Braunstein maps the contested moral landscape in which Americans experience and make sense of the tax system. Braunstein tells the stories of Americans who view taxpaying as more than a mundane chore: antigovernment tax defiers who challenge the legitimacy of the tax system, antiwar activists who resist the use of their taxes to fund war, antiabortion activists against “taxpayer funded abortions,” and a diverse group of people who promote taxpaying as a moral good. Though taxpaying is often portrayed as dull and technical, exposure to collective rituals, civic education, propaganda, and protest transforms the practice for many Americans into either a sacred rite of citizenship or a profane threat to what they hold dear. These sacred and profane meanings can apply to the act of taxpaying itself or to the specific uses of tax dollars. Despite intense disagreement about these meanings, politically diverse Americans engaged in both taxpaying and tax resistance valorize the individual taxpayer and “my tax dollars.”Braunstein explores the profound implications of this meaning making for tax consent, the legitimacy of the tax system, and citizens' broader understandings of their political relationships. Going beyond the usual focus on tax policy, Braunstein's innovative view of taxation through the lens of cultural sociology shows how citizens in value-diverse societies coalesce around shared visions of the sacred and fears of the profane. Interviewee: Ruth Braunstein is Associate Professor of sociology at the University of Connecticut. Host: Schneur Zalman Newfield is an Associate Professor of Sociology and Jewish Studies at Hunter College, City University of New York, and the author of Degrees of Separation: Identity Formation While Leaving Ultra-Orthodox Judaism (Temple University Press). Visit him online at ZalmanNewfield.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/book-of-the-day

Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious.  Do you know your nostalgia? ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠bfopnetwork.com⁠

Wells Fargo Bank Vice Chairman Doug Braunstein discusses how the Trump Trade is reshaping the investment landscape, mergers, and his plans for Wells Fargo with Bloomberg's Scarlet Fu and Romaine Bostick.See omnystudio.com/listener for privacy information.

Dundermoose returns to discuss the recent online battles over the Braunstein play style and how a peaceful resolution might be reached. Music by John Page T-shirts and more available on TeePublic Rollin' Bones is live every Tuesday night at 8 PM Central Want to create live streams like this? Check out StreamYards --- Support this podcast: https://podcasters.spotify.com/pod/show/rollin-bones/support

Amid the many events taking place at the Fair today - we had the chance to talk to Sandi Braunstein a disabled veteran with DAV of Minnesota about her overcoming injury to play adaptive sports. attending Winter Sports Clinics in Colorado and she shares how other disabled veterans can get involved!

Amid the many events taking place at the Fair today - we had the chance to talk to Sandi Braunstein a disabled veteran with DAV of Minnesota about her overcoming injury to play adaptive sports. attending Winter Sports Clinics in Colorado and she shares how other disabled veterans can get involved!

Let's talk about BRAUNSTEIN style games! Dubzaron's Shuckstein, featuring The Shucked Oyster and Gangbusters! Plus we'll review A Quiet Place Part One!

Sarah Braunstein reads her story “Abject Naturalism,” from the July 29, 2024, issue of the magazine. Braunstein is the author of two novels, “The Sweet Relief of Missing Children” and “Bad Animals,” which was published earlier this year. She is a recipient of the National Book Foundation's “5 Under 35” Award. 

In this episode of the Psychedelic Medicine Podcast, Mark Braunstein, DO joins to discuss the promise and the peril of ketamine. Dr. Braunstein graduated medical school in 1997 then completed a General Psychiatry Residency at the University of New Mexico and then a fellowship in Child and Adolescent psychiatry at Maine Medical Center in 2002. Upon graduation from his fellowship and becoming board certified in general psychiatry he established a private practice in Durango, Colorado where plant medicine became part of his everyday integrative psychiatric practice.  In this conversation, Dr. Braunstein shares some of the developments in the world of ketamine in the past three years since his previous episode, drawing on his own experience providing ketamine-assisted therapies. He stresses issues of grandiosity that can arise both when working with ketamine and when taking the medicine—issues which in the worst case and fuel ketamine use disorders. Dr. Braunstein stresses the importance of clinicians providing ketamine treatments being realistic and upfront about the potential harms of ketamine when advising prospective patients. In closing, he warns against the dangers of being in an echo chamber which reinforces potentially pathological substance use, especially for clinicians in the ketamine space.    In this episode you'll hear: Why ketamine has an addictive potential and how ketamine addiction presents Ways to treat ketamine use disorder  The importance of informed consent What patients should look for when seeking a ketamine provider The importance of ketamine providers working with multiple modalities and having multiple tools in the toolbox besides ketamine    Quotes: “Here's what's scary to me about ketamine: these people that I've seen having problems [with ketamine use] are largely lifetime recreational psychedelic/drug users without problems. And these are people who have made it to age fifty, smoking [cannabis], tripping a little bit, their whole life without having a problem—then at fifty years old, find themselves hooked on something for the first time.” [12:30] “[Ketamine] is not a microdosing medication… There is no such thing as ketamine microdosing. You think of microdosing as sub-perceptual. Everyone that I've met that's abusing ketamine, it was not a sub-perceptual effect—they were very much abusing it to have that perceived effect. Maybe not a psychedelic effect—usually an intoxicated wonky effect is what they're going for. And people refer to that as microdosing. It's not microdosing. It's abusing small doses.” [17:11] “What do I see that makes me concerned with someone I'm talking to—a clinician or a client? That grandiosity. So that gets me concerned right away when I hear about these ‘downloads' because that's where … other psychedelics can have dependency too. You see people … they go for aya ceremonies every week after week after week. So there can be an addiction to the download or to the release.” [34:35] “The people I know that have been successful in this line of work (from a patient standpoint), whether they're a clinician or not, have been the ones that have embraced the work. And just knowing that this is going to be a process and I'm in it to win it, for life. I'm working on myself.”  [35:40]   Links: Dr. Braunstein on LinkedIn Ketamine Research Foundation website NeuPath Mind Wellness website  Ketamine Training Center website Previous episode: Ketamine for Alcohol Use Disorder with Steven Mandel, MD Previous episode: Avoiding the Traps of Psychedelic Self-Absorption with Adam Aronovich, PhD(c) Previous episode: Navigating Psychedelic Narcissism with Adam Aronovich Previous episode: Psychedelic Therapy: Slow Down to Heal Faster with Sunny Strasburg, LMFT  Psychedelic Medicine Association Porangui

With a distinguished career spanning over three decades, Glenn Braunstein stands as a pioneering figure in the field of marriage and relationship coaching. His journey began in the complex world of family law, where he honed his skills and empathy as a paralegal specializing in matrimonial cases. This rich background laid the foundation for his transition into a revered marriage and relationship coach. Glenn brings a unique perspective to his coaching practice, deeply rooted in his Christian faith and an understanding of Biblical polygamy. This distinctive viewpoint allows him to offer specialized guidance not only to traditional couples but also to polygamous families, navigating them through the intricacies of their relationships with wisdom and compassion. An avid student of the Bible for over four and a half decades, Glenn's profound knowledge of scripture informs his holistic approach to relationship coaching. His expertise has empowered hundreds of individuals, both husbands and wives, to explore and strengthen their connections with one another. Throughout his career, Glenn has observed a common thread in the multitude of divorce cases he encountered: a profound disconnection and misunderstanding within the marital relationship, often exacerbated by infidelity or a breakdown in partnership roles. These observations have fueled his passion for addressing the deep-seated issues plaguing marriage in modern society. Connect with Glenn Braunstein: glenn@glennbraunstein.com Subscribe to the Kowalski Analysis Podcast: iTunes: https://apple.co/3aOeqNJ Spotify: https://spoti.fi/2CPn6a2 Google Play: http://bit.ly/GoogleKowalskiAnalysis Please complete this form to apply for my 'Man of Options' one-on-one coaching: http://tinyurl.com/39292xcr Join me on Patreon:   / biblicalpolygyny Join our Communities (100% free):  / unpluggedchristian / biblicalfamilies --- Support this podcast: https://podcasters.spotify.com/pod/show/robbkowalski/support

Todd Braunstein v. CHP

In this season's Flashlight episodes, we're taking a deep dive into the history of Dungeons and Dragons. Whether you love it, hate it, or are grimly resigned to playing it because everybody already knows the rules, the long history of D&D parallels the history of modern TTRPGs. We're starting out in the 1960s and working forward to the present day.This week, we try to talk about the wargames of the pre-D&D era. Along the way, we end up exposing our lack of knowledge of 1790s Prussia, discussing the travails of tavern ownership, and announcing a wholly fictitious live podcast tour. It's our first time back in the studio one-on-one in a while, and as a result we get a little silly.Here are some links that we used in research for the episode:This guide to running a Braunstein RPG is an excellent and comprehensive resource with links to plenty of other resources.This article from Ben Robbins (the creator of Microscope!) adds some more flavour to David Wesley's history with tabletop games.The first and second volume of Strategos explore the really deep history of wargames, which were the precursor to TTRPGs.Also, in this episode, Reilly asks Jake about the history about student loans, and Jake doesn't have a good answer. Jake, who writes the show notes, is still mortified about this. Here's a very long and detailed history of student loans.Follow us wherever you get your podcasts, including Spotify, Apple Podcasts, and YouTube. You can also get episodes right from the source at our RSS feed. If you enjoy Campaign Spotlight, consider subscribing to our Patreon. For more on the show, including links to all our social media, visit our website. 

Classical violinist Guy Braunstein has just released a record that revisits the Fab Four's classic "Abbey Road". It was recorded in the mythical London studios. He popped by FRANCE 24 to tell us more about what inspired him to revisit The Beatles and how there are only two categories of music: good and bad. We also look at new releases from Bon Jovi, Eminem and Manu Chao.

Accomplished conductor Ronald Braunstein founded an orchestra to help classical musicians with mental illness. Here's what we talk about in this episode: Art, Commuity, Creativity, Diversity, Entertainment, Illness, Inclusion, Inspiration, Mental health, Multicultural, Music, Treatment

Beth Golay recently spoke with Sarah Braunstein about "Bad Animals," how perspective shapes a novel, and more.

In this episode I that a look into 4D roleplaying as discussed by Sameøldji on episode 14 of their podcast The Four Dimensional Model of Roleplaying. https://open.spotify.com/episode/035cpq8HK6aK3ekVSI3ln9?si=UYL2wQVhTLqnoL-UWXIfyA I also came across a couple of YouTube videos that relate to the topic. Firstly, Quintin “Quinns” Smith takes a trip to Singapore to investigate the phenomenon of Jubensha for People Make Games. https://youtu.be/6_dlxbGUNNQ?si=cs6FXHpb-XHv2frV Also check out Quinns of the latest Bastionland Podcast episode. https://open.spotify.com/episode/4zGimNQaFxAa5lXwpq5GaQ?si=IFjiAbXgQN6yNxwBv8DbVA Here's Ben “Questing Beast” Milton getting to experience Dave Wesely's Braunstein. https://youtu.be/P-zzrWAQcWQ?si=5PyTo4FLqXxNbiJJ Honour mentions: Anthony “Runeslinger” Boyd of Casting Shadows, Che Webster of Roleplay Rescue and Daniel Jones' of Primæval Fantasy.Music by Timothy J. Drennon "Warning" by Lieren of Updates From the Middle of Nowhere Leave me an audio message via ⁠https://www.speakpipe.com/KeepOffTheBorderlands You can email me at ⁠spencer.freethrall@gmail.com⁠ You can find me in a bunch of other places here ⁠https://freethrall.carrd.co⁠ You can also find me on Discord by searching for FreeThrall/KeepOffTheBorderlands#762 This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit freethrall.substack.com

In this episode of the Plant Medicine Podcast, Dr. Mark Braunstein returns to discuss potential concerns surrounding the use of ketamine, especially use which is not overseen by a knowledgeable medical professional. Dr. Braunstein is a whole-health psychiatrist with 22 years of clinical experience. He is the medical director for multiple mental health and psychedelic psychotherapy clinics in Colorado, New Mexico, and Utah and he also runs in-patient and out-patient programs for addiction. Additionally, Dr. Braunstein is involved in multiple projects focused on expanding access, awareness, research, and safety in the field of psychedelics. To begin this conversation, Dr. Braunstein shares how his original exposure to ketamine wasn't in a medicinal context, but rather as a recreational drug of abuse. However, since then he has seen the transformative effects this substance can have on patients when used in a physician-directed context and for therapeutic purposes. Nonetheless, Dr. Braunstein stresses that this does not mean ketamine use does not come with certain risks. Ketamine can be addictive and even carries a risk of overdose, particularly when used recreationally in a context where the purity of the substance is unknown. Dr. Braunstein distinguishes recreational and therapeutic uses of ketamine, explaining that recreational doses are often lower and dosing is more frequent, whereas ketamine is used in high doses in a therapeutic context, with extended periods between sessions. Dr. Braunstein stresses both the responsibility of physicians and of patients to ensure ketamine is prescribed responsibly and used as directed. Despite the dangers posed by recreational ketamine use Dr. Braunstein describes in this conversation, it is still a medicine he believes can have significant positive impacts for patients. This requires, however, that it not be treated merely as yet another quick fix pill. Instead, Dr. Braunstein emphasizes that ketamine treatment ought to coincide with psychotherapeutic work. This combination, he says, will maximize the therapeutic potential of ketamine while also helping to ensure that the medicine is used responsibly, under the close direction of a medical professional.   In this episode: The addiction and overdose potential with recreational ketamine use How dosage can dramatically change the effects of ketamine Responsible prescribing practices for physicians working with ketamine The psychological and physiological harms of ketamine abuse How Dr. Braunstein talks to his patients about responsible use before prescribing ketamine The importance of combining psychedelic medicines with psychotherapeutic work   Quotes: “Part of why ketamine works is because it lights up your brain in all these different ways and when done occasionally, intentionally, it moves you. But if you're always doing that, it ends up having the reverse effect, causing damage.” [12:56] “This is a heavy-duty medication that, if you cross the line, can cause you to stop breathing and then die. So there is an actual, real danger to ketamine.” [16:25] “I think the organ that is most prone to damage from overuse of ketamine is the same organ we are touting it fixing: the mind.” [18:39] “When we think about these medications, we should think about combining them with therapy and not just taking these medications as medications… So that's why with ketamine I'm really recommending it with therapy.” [25:04]   Links: Reconscious Medical Psychedelic Medicine Association Porangui

In this JCO Article Insights episode, Giselle de Souza Carvalho provides a summary on  "Pathologic Exploration of the Axillary Soft Tissue Microenvironment and Its Impact on Axillary Management and Breast Cancer Outcomes" by Naoum, et al and "Optimization of Breast Cancer Regional Nodal Management" by Braunstein et al published in the January 10, 2024 issue in Journal of Clinical Oncology. The original report discusses how the examination of axillary soft tissue beyond lymph nodes is often omitted and it predicts breast cancer outcomes and need for nodal radiation. TRANSCRIPT The guest on this podcast episode has no disclosures to declare.  Giselle Carvalho: Welcome to the JCO Article Insights episode for the February issue of the Journal of Clinical Oncology. This is Giselle Carvalho, your host, one of the ASCO editorial fellows at JCO this year. Today, I'll be providing a summary of an article focused on “The Association of Axillary Soft Tissue Involvement on Outcomes for Breast Cancer Patients.” It was published in November 2023 and was partially presented at the 64th Annual ASCO in October 2022. Although lymph node involvement in breast cancer patients is correlated with a worse prognosis, the impact of extracapsular involvement is still a matter of debate, and the implications of axillary soft tissue involvement are still not fully understood. There is some evidence indicating a decrease in disease-free survival for patients with less than four lymph nodes and with extracapsular extension, while other studies show that extracapsular involvement has no prognostic role in these patients and that the number of positive lymph nodes might matter more. Patients with node-positive disease may present with only lymph node involvement or lymph node involvement plus extracapsular extension and/or axillary soft tissue involvement. The axillary soft tissue involvement can result from either direct lymph node extension through the capsule or direct microscopic spread from the primary tumor. It is pathologically defined in this article as axillary lymphatic channel invasion, axillary soft tissue deposits, axillary blood vessel invasion, or any combination of these. This was a retrospective study of patients with invasive breast cancer who received treatment at Massachusetts General Hospital in Boston, Massachusetts, from 2000 to 2020. Lymph nodes and surrounding adipose tissue were submitted in their entirety for histopathologic evaluation using hematoxylin and eosin stain, and immunohistochemical stains could be added at the pathologist's discretion. Eligibility criteria included primary breast cancer and positive lymph nodes without prior or contralateral breast cancer. 2,162 patients were included. They were divided into four groups according to their axillary pathology: the first group was composed of patients with positive lymph nodes with no additional axillary involvement; the second group of patients with positive lymph nodes and extracapsular involvement; the third group of patients with positive lymph nodes and axillary soft tissue involvement but with no extracapsular extension; and the fourth group of patients with positive lymph node and both extracapsular extension and axillary soft tissue involvement. Primary endpoints were 10-year rates of local-regional failure, which was defined as recurrence in the breast or chest wall or ipsilateral axilla, axillary failure, and distant metastasis. Among 2,162 patients, 58% had lymph node involvement only, 25% had lymph nodes with extracapsular extension, 3.5% had lymph node involvement with axillary soft tissue involvement, and 14% had lymph node involvement with both extracapsular and axillary soft tissue involvement. 51% of cases of axillary soft tissue involvement were in the form of axillary lymphatic channel invasion. The median follow-up was 9.4 years, and 74% of the cohort had hormone receptor-positive breast cancer, 10% had triple-negative disease, and 16% had HER2-positive disease. The groups with axillary soft tissue involvement, extracapsular extension, or both had more advanced tumor pathologic features when compared to the lymph node-only group, including a higher median size of breast tumors, a higher number of malignant lymph nodes, and an increased likelihood of breast lymphovascular invasion. Additionally, more patients in these three groups received mastectomy, axillary lymph node dissection, regional lymph node radiation, and systemic therapy. The lymph node-only group had the lowest 10-year incidence of distant failure, 13%, while the group with extracapsular extension and the group with axillary soft tissue involvement both had a 23% rate of distant failure at 10 years. The risk of distant failure reached an impressively high rate of 42% for the group with both extracapsular extension and axillary soft tissue involvement. Considering 10-year local-regional failure, the first group had a 6.2% rate, the second group a 5.7% rate, the third group a 10% rate, and the group with lymph node positivity with extracapsular extension and axillary soft tissue involvement had a 14% rate. The 10-year axillary failure rates were only 1.6% and 0.8% for the groups with no axillary soft tissue involvement but rose to 4.6% and 4.5% for the groups which did have axillary soft tissue involvement. In multivariable analysis, including tumor size, grade, number of positive nodes, and receptor status, axillary soft tissue involvement remained significantly associated with distant failure with a hazard ratio of 1.6, local-regional failure with a hazard ratio of 2.3, and axillary failure with a hazard ratio of 3.3. Of note, the number of axillary failures was overall low, only 4.6% in the group with both lymph node and axillary soft tissue involvement. Delivery of regional lymph node irradiation, defined as treatment of axillary, supraclavicular, and internal mammary nodes, was associated with improved local-regional outcomes in patients with extracapsular extension or axillary soft tissue involvement with a hazard ratio of 0.5 and a p-value of 0.03 but was not associated with any improvement in distant failure. The authors described the main limitations of this study as the retrospective nature and the absence of genomic marker results. In summary, although current guidelines do not emphasize axillary soft tissue examination, this study shows the importance of reporting axillary soft tissue involvement beyond the number of positive lymph nodes and the presence of extracapsular extension, as there is an increase in local-regional, and axillary failure rates for patients with axillary soft tissue involvement even without extracapsular extension. Therefore, both extracapsular extension and axillary soft tissue involvement should be consistently reported in large randomized trials as we continue to work to tailor local therapy to individual patient risk. This is Giselle Carvalho. Thank you for your attention and stay tuned for the next episode of JCO Article Insights. The purpose of this podcast is to educate and inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.  Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.        

Episode 174 streamed live Tuesday January 16, 2024 Main Topic: What are the OSR's of today? Old School Renaissance or Old School Revival A little History:https://en.wikipedia.org/wiki/Old_School_Renaissance A couple of primers: A Quick Primer for Old School Gaming (Matt Finch and Mythmere Games 2008): https://ia601802.us.archive.org/28/items/a-quick-primer-for-old-school-gaming/A%20Quick%20Primer%20for%20Old%20School%20Gaming.pdf 2. New OSR Primers (Lumpkin, Milton, & Perry):https://drive.google.com/file/d/1VSa6hSvQAlyvkTfmqhix1Z2EoFJPR-CP/view The Different Flavors of the OSR today https://osrsimulacrum.blogspot.com/2021/12/a-historical-look-at-osr-part-v.html “It was simply a rebirth of interest in old-school Dungeons & Dragons, specifically as its original designers intended it to be played. Its adherents had never entirely disappeared, but it was certainly a playerbase on life support for the longest time. Around 2007 began a renaissance, one that manifested in a variety of ways but at its heart was firmly rooted in mechanical compatibility with TSR-era D&D and a sharing of certain key design principles that went with those editions and the way their designers intended them to be played…” The main four variants: Classic OSR: The original wave. Has both compatibility and principles. OSR-Adjacent: Some principles, some compatibility. NSR: Principles, but not compatibility. Commercial OSR: Compatibility, but not principles. OTHERS: FKR:Free Kriegsspiel Revolution Numbers don't add up to a game. If the fiction fits, try it. You play worlds, not rules. https://followmeanddie.com/2021/10/02/fkr-free-kriegsspiel-revolution/ Great video by ben Milton of Questing beast for overview:https://youtu.be/d4lvrC3ZBzM BRoSR:https://youtu.be/JIEW2r6deXs “AD&D 1st edition with absolutely no house rules, do every single thing Gary told you to do." Also patron play / Braunstein where many domain level characters that would be NPC are run by the players" More annoying links: 1) https://jonmollison.com/2022/11/10/brosr-principles-a-primer/ 2) https://bdubsanddragons.blogspot.com/2021/11/bdubs-essential-guide-to-patron-play.html 3) https://bdubsanddragons.blogspot.com/2021/07/jeffrogaxian-time-keeping-vs-variable.html Live Character Creation Let's create a character with as many random rolls as possible using Horde Wars! Random Geek-itude Big Geek Con 2 Dates: September 20-22, 2024 (Times TBD) Four Points by Sheraton Saginaw Our Links: Cash Support PayPal: https://paypal.me/biggusgeekus Streamlabs: https://streamlabs.com/biggusgeekus1/tip Ko-fi: https://ko-fi.com/biggusgeekus Patreon: https://www.patreon.com/BiggusGeekus On the Web:  Website: www.biggusgeekuspodcast.com Email: thegeeks@biggusgeekuspodcast.com Big Geek Emporium: https://biggeekemporium.com/ --- Send in a voice message: https://podcasters.spotify.com/pod/show/biggusgeekus/message Support this podcast: https://podcasters.spotify.com/pod/show/biggusgeekus/support

Daddy Warpig and Dorrinal talk about D&D, the latest Hunger Games, and whatever else comes up! https://jeffro.wordpress.com/2023/11/17/trollopulous-adjusted-session-48-the-charge-of-the-douche-brigade/

Sound is one of the most important parts of how people perceive their surroundings – and yet it's usually left out of the design experience. It's time for buildings to have a soundtrack, according to Layne Braunstein, Leader, Creative, at ESI Design, an NBBJ studio. In this session, Braunstein, who has created multisensory experiences for brands like Google, Sonos, and Microsoft, will explore how new technologies are making it possible for buildings and spaces to harness the power of sound to create feelings of calm, excitement, or nostalgia, increase productivity and well-being, and even create hyper-personalized experiences that respond directly to your current mood.

The New Role of Blood Tests in Helping to Diagnose Alzheimer's Disease Lori La Bey talks with Dr. Braunstein the CEO and president of C₂N Diagnostics, a specialty diagnostics company with a vision to bring Clarity Through Innovation®. The company's Precivity™ tests are innovative new blood tests intended for use in patients with cognitive impairment. These tests aim to help healthcare providers determine the presence or absence of amyloid plaques in the brain, a hallmark sign of Alzheimer's disease, and aid in medical management and treatment decisions. Learn: What is C2N Diagnostics working on? What are the 3 types of Precivity tests? How fast do the blood tests get turned around for results?  Are all Precivity tests needed? Is genetic counseling set up as support for those taking the APOE tests? What is the cost-effectiveness of the Precivity tests compared to other tests such as MRIs and PET Scans? Is there a financial assistance program for the Precivity tests?   Listen and Subscribe to Alzheimer's Speaks on Apple Podcast https://podcasts.apple.com/us/podcast/alzheimers-speaks/id986940432   Listen and Subscribe to Alzheimer's Speaks on Spotify https://open.spotify.com/show/255okRnEgfCUqXq1NWcrT3   Contact  C2N ADiagnostics Website  www.precivityAD.com X - Twitter  @C2NDiagnostics Facebook  www.facebook.com/C2NDiagnostics   Contact Lori La Bey with questions or branding needs at https://www.alzheimersspeaks.com/ Alzheimer's Speaks Radio - Shifting dementia care from crisis to comfort around the world one episode at a time by raising all voices and delivering sound news, not just sound bites since 2011. Alzheimer's Speaks is part of the Senior Resource Podcast Network.  Support this Show: https://alzheimersspeaks.com/donate-now/See omnystudio.com/listener for privacy information.

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I don't know about you, but one of my least favourite things to see on my consult list is a cat with a snotty nose. The idea that my patient's problem can be anything from a self-limiting mild disease to a serious and frustrating impossible-to-treat condition, and the decision-making around this, fills me with uncertainty and dread. This episode aims to replace that uncertainty with confidence, or at least a solid plan based on sound knowledge! Dr Kath Briscoe is a Specialist in Feline Medicine who has worked in academic and specialist referral centres and as a referral clinician in a GP setting, and her experience gives her a great insight into the frontline work that we deal with in a non-referral setting. Dr Megan Braunstein is a practice owner and practicing clinician with a Masters in Small Animal Medicine and Surgery and many years of experience. Her practice in Perth, Western Australia, submitted the most feline respiratory PCR panels of any practice on Australia last year, and she helps us unpack what they're learning about these tests. Between them, they'll refresh your foundational knowledge about infectious causes of feline upper respiratory disease and help with decision-making around diagnostics and treatment. We delve into what's new in the world of diagnostics with a review of feline respiratory disease PCR panels, including learning what it's great for, when to use it, and how to do it. This episode is supported by our friends at the SVS Pathology Network, which our Australian listeners will know better as Vetnostics, QML Vetnostics, ASAP Laboratory and Vetpath Laboratory Services. The SVS  Pathology Network provides a wide range of infectious disease PCR tests, including a comprehensive panel for feline respiratory pathogens. Their PCR panels are designed for detecting Australian pathogens, and they have recently introduced additional pathogens on several of their PCR panels. Our guests provide a detailed guide on how to take samples for PCR in this conversation, but your state-based SVS Pathology Network laboratory customer care team are always happy to answer any questions. Topic list: 1. Feline upper respiratory diagnostics: who needs what? [00:00:00-00:05:00] 2. Discussion of different types of feline upper respiratory diseases [00:05:00-00:06:00] 3. Importance of husbandry and stress management in preventing feline upper respiratory diseases [00:16:00-00:31:00] 4. Hygiene practices for cat households and catteries [00:31:00-00:33:00] 5. Overview of infectious causes of feline upper respiratory diseases [00:02:00-00:08:00] 6. Discussion of feline herpesvirus and its symptoms [00:08:00-00:12:00] 7. Discussion of feline calicivirus and its symptoms [00:12:00-00:14:00] 8. Discussion of other infectious causes of feline upper respiratory diseases [00:14:00-00:16:00] 9. Vaccines for preventing feline upper respiratory diseases [00:16:00-00:18:00] 10. Overview of diagnostic tests for feline upper respiratory diseases [00:18:00-00:20:00] 11. Discussion of PCR panels and their usefulness in diagnosing feline upper respiratory diseases [00:20:00-00:22:00] 12. Discussion of treatment options for feline upper respiratory diseases [1, 00:24:00-00:28:00] Join our community of Vet Vault Nerds to lift your clinical game and get your groove back with our up to date easy-to-consume clinical episodes at ⁠vvn.supercast.com, ⁠visit ⁠thevetvault.com⁠ for the show notes and resources for this episode, and connect with us through our online ⁠Vet Vault Network.⁠ for episode highlights, discussions, questions and support. Subscribe to our weekly newsletter ⁠here⁠. Come help us create some live clinical content at ⁠⁠IVECSS '23⁠⁠ in Denver, Colorado from 7-11 September. Get up and running (or working!) with a 10% discount for ⁠Tarkine⁠ shoes, the official shoe of the Vet Vault. (discount automatically applied at checkout using this link). --- Send in a voice message: https://podcasters.spotify.com/pod/show/vet-vault/message

Due to issues with the previous upload, we've decided to just reissue this one. Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious.  Do you know your nostalgia?  bfopnetwork.com

Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious.  Do you know your nostalgia?  bfopnetwork.com

Caroline Whiddon thought she was going to play French horn professionally, but panic and anxiety had other ideas. Fortunately, orchestra administration turned out to be her true home, ultimately leading her to co-found the Me2/ orchestra with her husband, conductor Ronald Braunstein. Braunstein's bipolar diagnosis left him unable to find work, and Me2/ is the world's only classical music organization created by and for individuals with mental illnesses and the people who support them. Caroline and I talk about the power of music to create change, what happens when you create stigma-free zones, the documentary, Orchestrating Change, that chronicles Me/2's journey, and more. Episode breakdown: [00:04:31] Following someone else's strict sense of music education vs. having a strong inner sense of musical identity. [00:07:36] Panic attacks derail performance career, and lead to orchestra administration instead. [00:16:44] Starting orchestra administration in Savannah. [00:22:49] Conductor Ronald Braunstein decides to start a non-auditioned orchestra for the mentally ill. [00:30:49] Challenging beginnings, slow growth, but incredible progress. [00:35:15] Integration breaks stigma, impacts everyone's lives. [00:41:08] Music for mental health, supporting and educating. [00:48:20] A chance discovery leads to inspiring documentary. [00:51:22] Film documents musician's journey despite challenges. [00:58:43] Signage promotes safe spaces, challenges stigma. [01:02:46] Strategic planning for expansion, focus on accessibility. Please leave a review and in it, tell us about a time when being fully seen made a difference to you. Want more? Here are some handy playlists with all my previous interviews with guests in music. Check out the show notes at fycuriosity.com, and join the conversation on Post.news, Spoutible, and Mastodon! If you'd like weekly updates, plus a chance to see what's going on in my world, check out my new (free!) Substack newsletter.

Paul Braunstein, such a talented actor! I am really glad to have had the opportunity to interview him... The reason why I wanted to interview him is because he is the first actor in the movie to be infected with the alien parasite, and for me that is a very big deal. Being the first to die in any horror movie is a big deal to me... And, I had to confirm with him to find out when in the movie his character was attacked and cloned. These things I need to know (and to confirm fan theories). Overall, The Thing (2011) is still in my Top 10 favorite horror movies and yes, I have concluded that this version is up there with John Carpenter's from 1982. Excitedly exceeding the talents of all other actors, Mr. Braunstein has reached that level in my opinion with his phenomenal acting talent and very impressive resume'. Although this version of being the prequel has made John Carpenter's movie a sequel; nonetheless and overall an outstanding movie. Now if we can get a director or producer to come up with a third rendition because the damn dog is still alive (I think). I could be wrong, but who knows... --- Send in a voice message: https://podcasters.spotify.com/pod/show/southjerseyhorror/message

Drs. John Sweetenham and Marc Braunstein discuss advances in hematologic malignancies featured at the 2023 ASCO Annual Meeting, including the potentially practice-changing SWOG-S1826 study in Hodgkin lymphoma, the promise of bispecific antibodies in B-cell malignancies, and a novel approach to deliver vital anti-myeloma medications that could improve patient quality of life and alleviate barriers to care. TRANSCRIPT   Dr. John Sweetenham: Hello, I'm John Sweetenham, the associate director for cancer network clinical affairs at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center and the host of the ASCO Daily News Podcast.    The 2023 ASCO Annual Meeting featured some exciting new data on hematologic malignancies. I'm delighted to have Dr. Marc Braunstein return to the podcast to discuss some of these potentially practice-changing studies and new approaches in the heme space. Dr. Braunstein is a hematologist and oncologist at the NYU Perlmutter Cancer Center.    You'll find our full disclosures in the transcript of this episode, and disclosures of all guests on the ASCO Daily News Podcast are available on our transcripts at asco.org/DNpod.   Marc, it's great to have you back on the podcast, and thanks for being here again.   Dr. Marc Braunstein: Thank you, John. It's great to be back.   Dr. John Sweetenham: Marc, we already mentioned that there are some potentially practice-changing studies that were reported at ASCO this year. And among those, LBA4, which was presented in the Plenary Session, was a study which explored the treatment of advanced Hodgkin lymphoma. This was the Southwest Oncology Group study S1826. Could you give us your insights on this?    Dr. Marc Braunstein: Sure, happy to discuss S1826. So as background, you know, the ECHELON-1 study, which was published in the New England Journal of Medicine in 2022 showed a 40% decrease in the risk of death at six years follow-up by adding brentuximab to AVD compared to bleomycin AVD. And that was in high risk or advanced-stage patients and that led to adoption of brentuximab for upfront use in patients with classical Hodgkin lymphoma in advanced stage.    Also of note, immune checkpoint inhibitors such as pembrolizumab or nivolumab do have activity in the relapse setting. The SWOG S1826 study was a randomized control study looking at the use of the PD-1 inhibitor nivolumab plus AVD versus brentuximab AVD in patients with advanced stage classical Hodgkin lymphoma who are at least twelve years of age. And the primary endpoint in the study was progression-free survival.     It was a large study which enrolled 976 patients and randomized them one to one to either nivo AVD or brentuximab AVD. The median age in the study was 27 and the median follow-up was 12 months. And what the study found, which could be practice-changing, was that the primary endpoint of progression-free survival was superior in the nivolumab arm with a hazard ratio of 0.8 and a one-year PFS of 94% versus 86%, favoring the nivolumab arm. And while there were side effects associated with the class of medications, for example, hypo or hyperthyroidism was more frequent in the nivolumab group, whereas peripheral neuropathy was higher in the brentuximab group, I think that these results are particularly encouraging for how we can continue to improve outcomes for patients with advanced-stage classical Hodgkin lymphoma. And this may be practice-changing in terms of whether we use upfront immune checkpoint inhibitors in combination with our standard chemotherapy backbone.    Dr. John Sweetenham: Yeah, absolutely. There are a couple of things that occur to me. One in particular which is unique about this study, and the fact that it was for patients who are 12 years and older in many respects represents a first because I can't think of another large, randomized study of this type which has attempted to align pediatric and adult care of patients with Hodgkin lymphoma. So, I think it's something of a landmark in that regard. I don't know if you'd agree with that.    Dr. Marc Braunstein: I agree, especially with the range of ages from 12 to 83. It's a pretty broad population by age, but I agree it does kind of reconcile those two groups in a disease that has a bimodal presentation and clearly shows that immune checkpoint inhibitors are both potent and well tolerated in different age groups.    Dr. John Sweetenham: The other question that I have about this study is we haven't seen so far in this study an overall survival benefit to the nivo arm, which is maybe not surprising, but in terms of the practice-changing potential of this study, do you think that will matter?   Dr. Marc Braunstein:  I think that's an excellent question, John. Initially, the ECHELON-1 study only showed progression-free survival, and then the update did show overall survival. And so if we take the lead from that study, we expect to see an overall survival benefit in the SWOG study as well with nivolumab, but it remains to be seen. But I think that the data presented thus far at the Plenary Session is compelling enough to consider using nivolumab upfront.   Dr. John Sweetenham: Yeah, I absolutely agree. And then I guess the other question that we're going to have to wait probably several years to know is what happens in terms of relapse? So, for the minority of these patients who do relapse, how salvageable, if that's the right word, are they going to be with a second- or third-line regimen? But I think that's clearly something for the future, and it's a very interesting, exciting outcome from this study.   Dr. Marc Braunstein: Absolutely.    Dr. John Sweetenham: Let's move on. Marc, again, we're still in the lymphoma world here, but looking at high-risk follicular lymphoma. And this was Abstract 7506, looking at epcoritamab plus the R2 regimen in patients with follicular lymphoma. Could you walk us through this one?    Dr. Marc Braunstein: Yeah, absolutely. Bispecific T-cell engaging antibodies are showing impressive efficacy in relapsed and refractory non-Hodgkin lymphoma. Epcoritamab is a bispecific antibody that binds to CD3 on T-cells and CD20 B-cells. And this antibody is currently approved for diffuse large B-cell lymphoma patients after two or more prior lines of treatment.    In this study presented by Merryman and colleagues, they explored the addition of epcoritamab to standard lenalidomide-rituximab. In 109 patients with relapsed or refractory follicular lymphoma who had at least one prior therapy, and, of note, the study was enriched for high-risk patients for progression, including those who had progression of disease within 24 months of their initial treatment and those patients who had been refractory to prior anti-CD20 treatment. This study enrolled 109 patients with relapsed refractory follicular lymphoma. The median age was 65 and 56% of patients had FLIPI scores on the higher end of the spectrum from three to five, and 61% had stage 4 disease. Also of note, 38% of patients had progression of disease within 24 months of their prior treatment. So at a median follow-up of 8.8 months, the overall response rate was impressive at 97%, and 82% of patients were still on treatment at that time.     Now, of course, with this mechanism of action of bispecific antibodies, there is a risk of both cytokine release syndrome and immune-related neurotoxicity. The rates of CRS were primarily low grade, there were only 2% grade 3, and of note, most occurred after the first dose. And in terms of ICANS or neurological toxicity, there were no grade 3 adverse events, and those occurred in only two patients. Finally, the estimated six months progression-free survival was 93%. So, if we cross-compare these results historically to the R-squared regimen, which was published to be about 80%, just cross comparing, so it's not exactly the same study, this clearly shows high activity on par or better with R-squared alone. Although this study was not a randomized study, I think the addition of epcoritamab certainly shows high overall response rates and we'll need randomized data to confirm the efficacy, but it's definitely encouraging in high-risk follicular lymphoma patients.   Dr. John Sweetenham: Thanks, Marc. I agree. I think these data are really enticing, in as much as the response rates are so high, but of course, it is follicular lymphoma, so we'll have to wait a while. But the thing that it does make me reflect on is that bispecific antibodies really are turning out to be remarkably effective in a range of B cell malignancies, so, it's very interesting to continue to watch this space.    I'm going to change gears now and talk about something completely different for a moment. And this was Abstract 1536. I think that many of us are in a position where we're now looking at how we deliver our clinical services, and particularly inpatient services, to patients with hematologic malignancy. And this study addressed that very specifically. Can I have your thoughts on that?   Dr. Marc Braunstein: Sure. In the context of how our therapies are improving, our approaches to how we manage patients clinically is changing too, in many ways for the better. So, various models exist for, you know, which practitioners manage oncology patients who happen to be admitted to the hospital. This abstract, which was performed by authors at a large medical center in New York, describes the use of a dedicated hematologic malignancy hospitalist for managing medicine-related issues. And the authors did comparisons of that service to a service primarily managed by oncologists. The authors compared things such as length of stay, whether the patients were discharged by noon, which is a hospital metric that's used for facilitating turnover of patients and space availability, as well as 30-day readmission rates among patients cared for by an oncology attending versus this heme malignancy hospitalist between July of 2021 and July 2022.    The outcomes showed that admissions to the heme malignancy hospitalists were, although less because that service was primarily for patients who required medicine-related issues as opposed to primarily oncologic issues, there were 95 admissions to that service versus 669 to the oncology service. There was a significantly shorter length of stay on the heme malignancies hospitalist service by about 2 to 5 days compared to the oncology hospitalist service. The rates of patients who were discharged by noon or the length of stay were similar between the two groups.    So, while this study is confounded by differences in acuity of disease between the services, using a dedicated heme malignancy hospitalist has many benefits, not just to offload the oncology-managed service, which may have a higher level of acuity, but also allow for a deviation of care for medicine-specific issues, to a hospitalist that's specifically trained in managing patients with hematologic malignancies and then dedicating the oncology specialty service to those who need acute oncologic care, such as those with leukemia or other high acuity diseases.    Dr. John Sweetenham: Thanks, Marc. I think it is really interesting to see some outcome data for this model of care. A number of centers I know are looking at an APP-led inpatient service for these types of patients, too, so it's going to be very interesting to see how further studies of these kinds of approaches continue to develop.    And on a related theme of changes in patterns of care, Abstract TPS1609 looked at home infusion and of course, this is something that really started to attract a lot more attention during the COVID-19 pandemic. But I wonder if you could walk us through some of the details of this poster.    Dr. Marc Braunstein: This study was presented as a poster proposing a prospective study looking at home infusion of the anti-CD38 monoclonal antibody daratumumab, which has a vital role in managing patients with newly diagnosed or relapsed multiple myeloma. And monoclonal antibodies have really revolutionized the care of patients with multiple myeloma, but often their infusion schedule is weekly or biweekly, and it does require relatively frequent visits to an infusion center.    So, this single-arm, open-label study is going to examine whether we can provide home administration of subcutaneous daratumumab and assess whether it improves quality of life and assess its safety. So, in this study, a visiting nurse will come and deliver the medication after patients take their pre-medications at home prior to the arrival of the infusion nurse. And then the investigators will provide quality of life questionnaires prior to and after the infusions and at the end of the study, and they'll be looking at any barriers to adherence, any barriers to the logistics of this home infusion arrangement.    And I think that this has a lot of potential not just to improve quality of life, but also to facilitate care to patients who may be frail, who may not have good caregiver support, who may have barriers in traveling to an infusion center or perhaps in places that are more resource-deprived and don't have local infusion centers. This could be a potential approach to delivering vital anti-myeloma medications at home, and I'm looking forward to seeing the results.    Dr. John Sweetenham: Yeah, I agree. I think a lot of us still have anxieties about the safety of this approach, but I think there are increasing data to suggest that home infusion is not only safe but also, as you mentioned, is a big enhancer of the quality of life of these patients. And so, very interesting to see how this plays out in prospective studies.    So, to close out, I wonder if you could walk us through Abstract 7072, a poster looking at the issue of clonal hematopoiesis.    Dr. Marc Braunstein: Clonal hematopoiesis, which is a phenomenon in which the blood cells acquire somatic mutation, is associated with both cardiovascular disease adverse outcomes as well as hematologic malignancy. It's been shown to be a precursor for diseases such as leukemia. So, this relatively small study from MD Anderson Cancer Center examined clonal hematopoiesis in 78 patients with malignancies, 70% of which had a history of cancer, and the authors described outcomes associated with clonal hematopoiesis.    So, again, 78 patients were examined, and 76% of them had a history of malignancy, and 73% had other comorbidities. And the authors demonstrated clonal hematopoiesis by the finding of specific mutations in the blood associated with clonal hematopoiesis. The authors essentially looked at outcomes such as mortality. They noted that only 20% of the patients developed a myeloid neoplasm, and that's relevant because, again, clonal hematopoiesis is a precursor for myeloid neoplasms. They also noted that most patients had died from a primary malignancy rather than a myeloid neoplasm, which is not too surprising considering that most patients with clonal hematopoiesis will not develop a hematologic malignancy, but it is a marker for the potential transformation.    And so, I think the authors conclude that clonal hematopoiesis is important for monitoring patients who are at risk for potential myeloid transformation and hematologic malignancy, but it's not necessarily the case that patients who have a background of malignancy will often develop a myeloid malignancy. I think there are many implications of clonal hematopoiesis for cancer in general in terms of the risk of secondary malignancies in those treated with adjuvant chemotherapy, in terms of how we monitor patients who actually more and more are going to have this detected as we use more next-generation sequencing and liquid biopsies.     So, I look forward to future studies that are exploring how to actually prospectively assess clonal hematopoiesis and use it for clinical stratification for things like adjuvant chemotherapy or monitoring for risks of hematologic malignancy.    Dr. John Sweetenham: Thanks, Marc. I agree. Very important for the future, especially as we gain more and more sequencing data.    So, Marc, in conclusion, I want to thank you very much for sharing your insights with us today on the ASCO Daily News Podcast. It's been great to talk with you again.    Dr. Marc Braunstein: My pleasure. Happy to be back, and I look forward to a future podcast session.  Dr. John Sweetenham: And thank you to our listeners for joining us today. You'll find links to the abstracts discussed today in the transcripts of this episode. Finally, if you value the insights that you hear on ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts.   Disclaimer:   The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.    Find out more about today's speakers:   Dr. John Sweetenham   Dr. Marc Braunstein   @docbraunstein      Follow ASCO on social media:    @ASCO on Twitter    ASCO on Facebook    ASCO on LinkedIn       Disclosures:   Dr. John Sweetenham:   Consulting or Advisory Role: EMA Wellness   Dr. Marc Braunstein:   Consulting or Advisory Role: Pfizer, Bristol-Myers Squibb/Celgene, Adaptive Biotechnologies, GlaxoSmithKline, ADC Therapeutics, Janssen Oncology, Abbvie, Guidepoint Global, Epizyme, Sanofi, CTI BioPharma Corp   Speakers' Bureau: Janssen Oncology   Research Funding (Institution): Janssen, Celgene/BMS        

Notre invité ne s'est pas fait d'amis dans le milieu universitaire quand il a osé s'attaquer en 2018 à la théorie du genre avec son livre, La philosophie devenue folle.  « Des collègues et des amis, souvent depuis plus de 30 ans, ont soudainement arrêté de me parler, du jour au lendemain. »   Une forme d'excommunication de son milieu universitaire: « C'est la mort sociale. » L'épisode a probablement nourri la réflexion de ce philosophe qui s'est beaucoup intéressé à l'histoire des sciences et à l'éthique médicale. Son plus récent ouvrage, La religion woke, postule que nous ne sommes plus en face d'un mouvement idéologique, mais davantage en présence d'une nouvelle religion. « Il y a un prosélytisme, des cérémonies de demandes d'expiation, des textes sacrés, des études qu'il faut citer, des processions et même l'équivalent d'un calendrier religieux. » Détail intéressant, son ouvrage a été salué à gauche comme à droite lors de sa sortie...un miracle!Pour de l'information concernant l'utilisation de vos données personnelles - https://omnystudio.com/policies/listener/fr

This week on Soul of the Nation, we continue our series on White Christian Nationalism by welcoming cultural sociologist Ruth Braunstein to the podcast. Braunstein is an Associate Professor of Sociology at the University of Connecticut, where she is Director of Undergraduate Studies and Director of the Meanings of Democracy Lab, which studies the moral and cultural foundations of American democratic life. Braunstein reveals the types of people who are attracted to White Christian Nationalism, what the phrase "Judeo-Christian" really means, and offers insights on how to persuade people away from Christian nationalist views. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

durée : 00:51:46 - Répliques - par : Alain Finkielkraut - Débat autour de la question du wokisme, objet de vives discussions dans la sphère politique et intellectuelle : avec Albert Ogien et Jean-François Braunstein. - invités : Albert Ogien sociologue; Jean-François Braunstein philosophe et historien des sciences, professeur de philosophie contemporaine à l'université Paris 1 Panthéon-Sorbonne

On this episode of Let's be Blunt, Montel talks with writer, art curator and cannabis advocate, Mark Braunstein. Mark smokes canna daily to control pain and spasms due to a spinal cord injury that rendered him partially paralyzed. He has testified before committees of the Connecticut legislature seven times over 14 years, urging passage of bills to legalize medical canna. His sixth and most recent book, Mindful Marijuana Smoking: Health Tips for Cannabis Smokers, was published in 2022. #cannabiseducation #cannabis #cannabiscommunity #cannabiseducation #420 #420daily Support the showFor More Let's be BLUNT with MontelInstagram https://www.instagram.com/letsbebluntmontel/orYouTube https://www.youtube.com/channel/UCMGyFAMo_k-0Q7Ui9DXCCmQ

Today we dig into the history of Dungeons and Dragons and look at what influences Gary Gygax and others drew from to create such an immersive and addictive RPG experience. We'll examine the long history of wargaming and fantasy literature to understand where games like D&D come from. And I'll lay out exactly how D&D came to be associated with Satanic influences. Fight! Fight! Fight! Fight! Fight! That'll make sense when you listen. Happy 2023 and Hail Nimrod!Wet Hot Bad Magic Summer Camps coming up quick!  Tickets go on sale the week of JANUARY 16TH. Whooooo!!!Bad Magic Productions Monthly Patreon Donation: We're giving to The Museum of Tolerance - the only museum of its kind in the world. The MOT is dedicated to challenging visitors to understand the Holocaust in both historic and contemporary contexts and confront all forms of prejudice and discrimination in our world today. For more information, you can visit www.museumoftolerance.com.Get tour tickets at dancummins.tv Watch the Suck on YouTube: https://youtu.be/unHXHwm9UfIMerch: https://www.badmagicmerch.comDiscord! https://discord.gg/tqzH89vWant to join the Cult of the Curious private Facebook Group? Go directly to Facebook and search for "Cult of the Curious" in order to locate whatever happens to be our most current page :)For all merch related questions/problems: store@badmagicproductions.com (copy and paste)Please rate and subscribe on iTunes and elsewhere and follow the suck on social media!! @timesuckpodcast on IG and http://www.facebook.com/timesuckpodcastWanna become a Space Lizard?  Click here: https://www.patreon.com/timesuckpodcastSign up through Patreon and for $5 a month you get to listen to the Secret Suck, which will drop Thursdays at Noon, PST. You'll also get 20% off of all regular Timesuck merch PLUS access to exclusive Space Lizard merch. You get to vote on two Monday topics each month via the app. And you get the download link for my new comedy album, Feel the Heat. Check the Patreon posts to find out how to download the new album and take advantage of other benefits.

Quantum computers are a cutting-edge technology that has the potential to transform businesses, society, and the planet for the better. IonQ is a leader in the quantum computing industry, with a mission to build the best quantum computers to solve the world's most complex problems. Ariel Braunstein, SVP Product and Marketing at IonQ, demystifies the quantum computing industry for us and takes us through what he perceives to be the future of technology as we know it.https://ionq.com/ 

Fatherhood is a journey. It's a winding path with ups and downs, twists and turns. And for first-time fathers, it can be a bit daunting. But don't worry, you're not alone. Here at A Dad's Path, we're dedicated to helping dads everywhere navigate fatherhood.This week, we're featuring Will Braunstein. Will has co-founded and led multiple companies, including USA Rx, a market-driven discount on prescription medications, and CastleWave, a full-service strategy consultancy and interactive agency. Will is a mentor for the University of Rochester and serves on the Board of Directors of Inside the Orchestra.Be sure to check out this episode of the BOF Podcast. Don't forget to like, share and subscribe!Join the Brotherhood of Fatherhood FB group at https://www.facebook.com/groups/brotherhoodoffatherhoodwww.brotherhoodfatherhood.com/alphaOrder the DAPPERGURU and get 10% on your order by using the code: Brotherhoodhttps://thedapperguru.com/?ref=PngnnQiFoV05N Direct Hemp: Get 15% discount on purchases from Direct Hemp!www.directhemp.com Use Code: brotherhoodOur sponsor: Jarvis Copy ai: https://jasper.ai/?fpr=scottr#BOFPodcast #brotherhoodoffatherhood #brotherhoodoffatherhoodpodcast #dad #father #podcast #fatherhood #parenting #masculinity #menleadingmen #personalgrowth

Pierre-Édouard Deldique reçoit dans Idées : Jean-François Braunstein, professeur de Philosophe contemporaine à l'Université Paris 1 Panthéon-Sorbonne. Il y enseigne l'histoire des sciences et la philosophie de la médecine, ainsi que l'éthique médicale. Il a notamment publié : Canguilhem. Histoire des sciences et politique du vivant (PUF) ; L'histoire des sciences. Méthodes, styles et controverses (Vrin) ; La philosophie de la médecine d'Auguste Comte. Vaches carnivores, Vierge Mère et morts vivants (PUF) ; et La philosophie devenue folle (Grasset). Il vient de publier « La religion woke » chez Grasset.

Lawrence Jay Braunstein is a partner in the law firm of Braunstein & Zuckerman, Esqs, in White Plains, New York. His practice includes the areas of Matrimonial and Family Law and related civil and criminal litigation. Since 1985 he has specifically focused his practice in the areas of child custody litigation, including parent-child contact problems and issues involving allegations of parental alienation and refuse/resist dynamics, and litigation involving allegations of child sexual abuse, physical abuse and abusive head trauma (shaken baby) in matrimonial, family and criminal cases. He is recognized by his peers as an expert in these areas and is often hired by other lawyers to assist them in their litigation because of his expertise in these areas.He regularly lectures as an invited speaker, both nationally and internationally, in the areas of child sexual abuse, physical abuse and shaken baby, child custody litigation, expert witness testimony, courtroom psychology, trial procedures, and on various other criminal, family and matrimonial law topics to judges, attorneys, medical and mental health professionals, law enforcement personnel (State and Federal), prosecutors (State and Federal), and child protection service personnel. Since 1999 he has served on the faculty of the New York City Police Department Sex Crimes and Child Abuse Investigation Course and, since 2014, on the faculty of the New York City Police Department Homicide Investigator Course. In 2004 he was the only defense attorney invited by the FBI to participate as a member of the working group to plan the International Online Child Sexual Victimization Symposium, and to present to both the working group and the Symposium. He has conducted hundreds of training with police departments across the county, with the FBI Behavioral Analysis Units, and with police agencies in England, Scotland, Wales, and South Africa. Outside of his practice, Larry believes in the importance of adequately training the next generation of lawyers in both litigation and non-litigation skills. To further that goal he serves as an Adjunct Professor of Law at Hofstra University School of Law in Hempstead, New York where he teaches Modern Divorce Advocacy, and Child Abuse and Neglect.Since 2007 he has been named as one of the “Top Attorneys in the New York Metro Area” as published in the New York Times Magazine's Super Lawyer Section, and one of the top Twenty-Five “Super Lawyers” in the Westchester County, New York, area. In 2014 he was rated “AV Preeminent” by the Martindale Hubbell Peer Review Ratings, indicating his high level of ethical standards and professional ability, generated from evaluations by other members of the bar and the judiciary in the United States and Canada. In 2018 he was included in Best Lawyers in America, and his firm was included in Best Law Firms in America.He is a Fellow of the American Academy of Matrimonial Lawyers and the International Academy of Family Lawyers.Larry is a respected member of the legal community and is involved in leadership positions with several professional organizations. He is a member of the New York State Bar Association, Family Law Section, Executive Committee and Former Co-Chair of the Committee on Child Custody; Past Legal Chair of the New York State Interdisciplinary Forum on Mental Health and Family Law, and Past Chair of the Westchester County Bar Association, Family Law Section. He is Vice President of the American Professional Society on the Abuse of Children (APSAC) New York Chapter, and a member of the Expert Faculty of the International Society for Prevention of Child Abuse and Neglect (ISPCAN). He is also a Past Co-President of the Association of Family and Conciliation Courts (AFCC) New York Chapter, and a member of the Board of Directors of AFCC International.Larry is a member of the Board of Editors of, and is a contributor to, the Journal of Child Custody&

Episode 211 of Rendering Unconscious Podcast. Dr. Renata Salecl is a philosopher and sociologist. She is Senior Researcher at the Institute of Criminology at the Faculty of Law in Ljubljana and a Professor at the School of Law, Birkbeck College, London, United Kingdom. Salecl has held numerous Visiting Professorships at Cardozo School of Law, New York, Humboldt University, Berlin, and Duke University, Durham, among other institutions. Her work is very interdisciplinary and focuses on bringing together law, criminology, the study of political ideologies, and psychoanalysis. http://renatasalecl.com This episode is dedicated to the loving memory of Dr. Néstor A. Braunstein. http://nestorbraunstein.com This episode available to view on YouTube: https://youtu.be/GC00SqX8jyQ You can support the podcast at our Patreon. https://www.patreon.com/vanessa23carl Your support is greatly appreciated! Rendering Unconscious Podcast is hosted by psychoanalyst Dr. Vanessa Sinclair: www.drvanessasinclair.net Find me on social media at: Twitter: https://twitter.com/rawsin_ Instagram: https://www.instagram.com/rawsin_/ TikTok: https://www.tiktok.com/@drvanessasinclair23 Visit the main website for more information and links to everything: www.renderingunconscious.org Rendering Unconscious: Psychoanalytic Perspectives, Politics & Poetry (Trapart 2019): store.trapart.net/details/00000 The song at the end of the episode is “Solitude (realm of the shadow)” by Vanessa Sinclair and Per Åhlund from the album “Follow My Voice” available from Highbrow Lowlife: https://vanessasinclairperhlund.bandcamp.com Many thanks to Carl Abrahamsson, who created the intro and outro music for Rendering Unconscious podcast. https://www.carlabrahamsson.com Image: Dr. Renata Salecl

Throwback Trivia Takedown takes trivia back to the glory days from the late 20th century to the early 2000's. Two challengers go head to head in a duel of the decades where the one with the most nostalgic knowledge of pop culture comes out victorious.  Do you know your nostalgia? bfopnetwork.com

Parshat Balak includes one of the most unique stories in the entire Torah, a story that the Talmud thought should be read every day. Why is it so special? Take Ten to find out.  This Ten is ponsored by the Braunstein family in memory of Marie Dweck a”h, Miryam bat Mordechai HaCohen.   

Daniel Braunstein is a producer who has worked with Volumes, Spiritbox, Dayseeker, and many others. Raad Soudani is the bassist and co-producer in Volumes. On this episode: Dark times lead to even darker music Why Raad Soudani wanted to work with Daniel Braunstein again How Opeth, Mike Patton, and The Beatles trained their fans to expect the unexpected Why you need delusional optimism  Hell froze over. Heavy music is mainstream again. Dealing with the tragic loss of Diego Farias How Daniel Braunstein approached working with Volumes this time around Metal bands hiring a co-writer: strictly forbidden or the norm? If you want long and successful relationships, know your role Listen to Volumes on Spotify. Follow Daniel Braunstein on Instagram. Follow Raad Soudani on Instagram. Want to level up your audio game? Sign up for URM. When you sign up, you'll get access to: Insanely detailed audio production tutorials One-on-one feedback Multi-track sessions from some of the biggest names in rock and metal Be sure to follow URM on Instagram and Facebook. Follow Eyal Levi on Instagram. Like this show? Please leave us a 5-star review - even one sentence helps! Learn more about your ad choices. Visit megaphone.fm/adchoices

T.S. Eliot ends his poem “The Hollow Men” with the line “This is the way the world ends…not with a bang, but a whimper.” Spree criminals are always after the bang. Many see themselves going out in a blaze of glory, taking as many people with them as they can. Going down in history as some kind of dark antihero, shaking up the way we think, making us question our most basic values—leaving a big, smoking crater in the earth on their way out of it. These guys are legends in their own minds. Funnily enough, though, as hard as they try for the big bang, they often end up with the whimper. And there's no better example of that than Peter Braunstein, a former playwright and fashion writer who--after being fired from his job at Women's Wear Daily--embarked on an outrageous crime spree. His ultimate goal? Kill Vogue Editor-in-Chief Anna Wintour. Join us for the bizarre story of a grudge that spun out of control.Sources:"Friend of the Devil" by Aaron Gell: https://humanparts.medium.com/friend-of-the-devil-3726bd1ddc1cInvestigation Discovery, "I Almost Got Away With It," Episode "I Got to Pose as a Firefighter"Gothamist: https://gothamist.com/news/peter-braunstein-endures-fellow-prisoners-teasing-you-didnt-even-rape-herhttps://en.wikipedia.org/wiki/Peter_BraunsteinFollow us, campers!Patreon (join to get all episodes ad-free, at least a day early, an extra episode a month, and a free sticker!): https://patreon.com/TrueCrimeCampfireFacebook: True Crime CampfireInstagram: https://gramha.net/profile/truecrimecampfire/19093397079Twitter: @TCCampfire https://twitter.com/TCCampfireEmail: truecrimecampfirepod@gmail.com