Podcasts about Jaha

Justin, Jaha, and Cory discuss the government shutdown and which side is winning. They also talk about the role of economics in politics and Marjorie Taylor Greene's problem with the Republican Party.Show Notes: https://abcnews.go.com/Politics/bad-night-democrats-face-blowback-party-shutdown-deal/story?id=127379532 https://www.theamericansaga.com/p/the-2025-election-proves-that-the?utm_campaign=post&utm_medium=web https://thehill.com/homenews/house/5600663-mtg-greene-trump-health-care-syria/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Dr Sharonne Hayes, Professor of cardiovascular medicine and founding director of Mayo Clinic women's heart clinic, and Dr. Marysia Tweet, Associate Professor of cardiovascular medicine, and co-leader of the Spontaneous Coronary Artery Dissection Registry and leader in women's heart health join the show for this amazing November chapter of Always on EM. They are world experts on Spontaneous Coronary Artery Dissection authoring over 60 peer reviewed articles on the topic and in this chapter we explore with them the pitfalls and pearls related to making this diagnosis in the ED. SCAD is an important cause of myocardial infarction especially in patients who would not otherwise seem to be at risk for heart attacks for example active young women without comorbidities, and its imperitive that we as emergency physicians are current on this diagnosis.   DONATE TO DR JIM GREGOIRE SCHOLARSHIP FUND To honor the life of Dr. Jim Gregoire, dear friend of this show, consider donating to his scholarship fund. Go to https://give.mayoclinic.org/give/616870/#!/donation/checkout Go to: What would you like your donation to support? Choose “other” Enter: James Gregoire Scholarship Fund   CONTACTS X - @AlwaysOnEM; @VenkBellamkonda; @Marysia_Tweet; @SharonneHayes YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch; @SharonneHayes Email - AlwaysOnEM@gmail.com   DO YOU HAVE SCAD? DOES YOUR PATIENT HAVE SCAD? WANT TO GET CONNECTED? SCAD Research: www.scadresearch.org National Coalition for Women with Heart Disease: www.womenheart.org Mayo Clinic Womens Heart clinic: https://www.mayoclinic.org/departments-centers/womens-heart-clinic/overview/ovc-20442061   REFERENCES & LINKS Saleh G, Al-Abcha A, Chaaban K, Adi MZ, Tweet M, Collins JD, Alkhouli M, Gulati R. Concomitant Takotsubo Cardiomyopathy and Spontaneous Coronary Artery Dissection: Exploring the Role of Cardiac Mechanics on Coronary Disruption. JACC Cardiovasc Imaging. 2025 Oct;18(10):1161-1166. doi: 10.1016/j.jcmg.2025.05.020. Epub 2025 Aug 5. PMID: 40758075. Baqal O, Karikalan SA, Hasabo EA, Tareen H, Futela P, Qasba RK, Shafqat A, Qasba RK, Hayes SN, Tweet MS, El Masry HZ, Lee KS, Shen WK, Sorajja D. In- hospital and long-term outcomes in spontaneous coronary artery dissection with concurrent cardiac arrest: Systematic review and meta-analysis. Heart Rhythm O2. 2025 Apr 24;6(6):843-853. doi: 10.1016/j.hroo.2025.03.023. PMID: 40717849; PMCID: PMC12287955. Morosato M, Gaspardone C, Romagnolo D, Pagnesi M, Baldetti L, Dormio S, Federico F, Scandroglio AM, Chieffo A, Godino C, Margonato A, Adamo M, Metra M, Tchetche D, Dumonteil N, Tweet MS, Saw J, Beneduce A. Left Main Spontaneous Coronary Artery Dissection: Clinical Features, Management, and Outcomes. JACC Cardiovasc Interv. 2025 Apr 28;18(8):975-983. doi: 10.1016/j.jcin.2025.01.427. Epub 2025 Apr 9. PMID: 40208153; PMCID: PMC12290918. Tweet MS, Pellikka PA, Gulati R, Gochanour BR, Barrett-O'Keefe Z, Raphael CE, Best PJM, Hayes SN. Coronary Artery Tortuosity and Spontaneous Coronary Artery Dissection: Association With Echocardiography and Global Longitudinal Strain, Fibromuscular Dysplasia, and Outcomes. J Am Soc Echocardiogr. 2024 May;37(5):518-529. doi: 10.1016/j.echo.2024.02.013. Epub 2024 Mar 11. PMID: 38467311; PMCID: PMC11605948. Tweet MS, Hayes SN, Grimaldo ABG, Rose CH. Pregnancy After Spontaneous Coronary Artery Dissection: Counseling Patients Who Intend Future Pregnancy. JACC Adv. 2023 Dec;2(10):100714. doi: 10.1016/j.jacadv.2023.100714. Epub 2023 Nov 14. PMID: 38915307; PMCID: PMC11194843. Tarabochia AD, Tan NY, Lewis BR, Slusser JP, Hayes SN, Best PJM, Gulati R, Deshmukh AJ, Tweet MS. Association of Spontaneous Coronary Artery Dissection With Atrial Arrhythmias. Am J Cardiol. 2023 Jan 1;186:203-208. doi: 10.1016/j.amjcard.2022.09.032. Epub 2022 Oct 31. PMID: 36328832; PMCID: PMC10403149. Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). Am J Cardiol. 2022 Jun 15;173:33-38. doi: 10.1016/j.amjcard.2022.03.005. Epub 2022 Mar 29. PMID: 35365290; PMCID: PMC9133198. Johnson AK, Tweet MS, Rouleau SG, Sadosty AT, Hayes SN, Raukar NP. The presentation of spontaneous coronary artery dissection in the emergency department: Signs and symptoms in an unsuspecting population. Acad Emerg Med. 2022 Apr;29(4):423-428. doi: 10.1111/acem.14426. Epub 2021 Dec 26. PMID: 34897898; PMCID: PMC10403148. Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLoS One. 2022 Mar 23;17(3):e0265624. doi: 10.1371/journal.pone.0265624. PMID: 35320296; PMCID: PMC8942215. Adlam D, Tweet MS, Gulati R, Kotecha D, Rao P, Moss AJ, Hayes SN. Spontaneous Coronary Artery Dissection: Pitfalls of Angiographic Diagnosis and an Approach to Ambiguous Cases. JACC Cardiovasc Interv. 2021 Aug 23;14(16):1743-1756. doi: 10.1016/j.jcin.2021.06.027. PMID: 34412792; PMCID: PMC8383825. Kok SN, Tweet MS. Recurrent spontaneous coronary artery dissection. Expert Rev Cardiovasc Ther. 2021 Mar;19(3):201-210. doi: 10.1080/14779072.2021.1877538. Epub 2021 Feb 26. PMID: 33455483. Campbell KH, Tweet MS. Coronary Disease in Pregnancy: Myocardial Infarction and Spontaneous Coronary Artery Dissection. Clin Obstet Gynecol. 2020 Dec;63(4):852-867. doi: 10.1097/GRF.0000000000000558. PMID: 32701519; PMCID: PMC10767871. Tweet MS, Young KA, Best PJM, Hyun M, Gulati R, Rose CH, Hayes SN. Association of Pregnancy With Recurrence of Spontaneous Coronary Artery Dissection Among Women With Prior Coronary Artery Dissection. JAMA Netw Open. 2020 Sep 1;3(9):e2018170. doi: 10.1001/jamanetworkopen.2020. PMID: 32965500; PMCID: PMC7512056. Hayes SN, Tweet MS, Adlam D, Kim ESH, Gulati R, Price JE, Rose CH. Spontaneous Coronary Artery Dissection: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020 Aug 25;76(8):961-984. doi: 10.1016/j.jacc.2020.05.084. PMID: 32819471. Johnson AK, Hayes SN, Sawchuk C, Johnson MP, Best PJ, Gulati R, Tweet MS. Analysis of Posttraumatic Stress Disorder, Depression, Anxiety, and Resiliency Within the Unique Population of Spontaneous Coronary Artery Dissection Survivors. J Am Heart Assoc. 2020 May 5;9(9):e014372. doi: 10.1161/JAHA.119.014372. Epub 2020 Apr 28. PMID: 32342736; PMCID: PMC7428589. Tweet MS, Akhtar NJ, Hayes SN, Best PJ, Gulati R, Araoz PA. Spontaneous coronary artery dissection: Acute findings on coronary computed tomography angiography. Eur Heart J Acute Cardiovasc Care. 2019 Aug;8(5):467-475. doi: 10.1177/2048872617753799. Epub 2018 Jan 29. PMID: 29376398; PMCID: PMC6027604. Tan NY, Tweet MS. Spontaneous coronary artery dissection: etiology and recurrence. Expert Rev Cardiovasc Ther. 2019 Jul;17(7):497-510. doi: 10.1080/14779072.2019.1635011. Epub 2019 Jul 5. PMID: 31232618. Waterbury TM, Tweet MS, Hayes SN, Eleid MF, Bell MR, Lerman A, Singh M, Best PJM, Lewis BR, Rihal CS, Gersh BJ, Gulati R. Early Natural History of Spontaneous Coronary Artery Dissection. Circ Cardiovasc Interv. 2018 Sep;11(9):e006772. doi: 10.1161/CIRCINTERVENTIONS.118. PMID: 30354594. Hayes SN, Kim ESH, Saw J, Adlam D, Arslanian-Engoren C, Economy KE, Ganesh SK, Gulati R, Lindsay ME, Mieres JH, Naderi S, Shah S, Thaler DE, Tweet MS, Wood MJ; American Heart Association Council on Peripheral Vascular Disease; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Genomic and Precision Medicine; and Stroke Council. Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association. Circulation. 2018 May 8;137(19):e523-e557. doi: 10.1161/CIR.0000000000000564. Epub 2018 Feb 22. PMID: 29472380; PMCID: PMC5957087. Tweet MS, Kok SN, Hayes SN. Spontaneous coronary artery dissection in women: What is known and what is yet to be understood. Clin Cardiol. 2018 Feb;41(2):203-210. doi: 10.1002/clc.22909. Epub 2018 Mar 1. PMID: 29493808; PMCID: PMC5953427. Tweet MS, Codsi E, Best PJM, Gulati R, Rose CH, Hayes SN. Menstrual Chest Pain in Women With History of Spontaneous Coronary Artery Dissection. J Am Coll Cardiol. 2017 Oct 31;70(18):2308-2309. doi: 10.1016/j.jacc.2017.08.071. PMID: 29073960; PMCID: PMC5957076. Lindor RA, Tweet MS, Goyal KA, Lohse CM, Gulati R, Hayes SN, Sadosty AT. Emergency Department Presentation of Patients with Spontaneous Coronary Artery Dissection. J Emerg Med. 2017 Mar;52(3):286-291. doi: 10.1016/j.jemermed.2016.09. Epub 2016 Oct 8. PMID: 27727035. Tweet MS, Gulati R, Williamson EE, Vrtiska TJ, Hayes SN. Multimodality Imaging for Spontaneous Coronary Artery Dissection in Women. JACC Cardiovasc Imaging. 2016 Apr;9(4):436-50. doi: 10.1016/j.jcmg.2016.01.009. PMID: 27056163. Tweet MS, Gulati R, Hayes SN. What Clinicians Should Know Αbout Spontaneous Coronary Artery Dissection. Mayo Clin Proc. 2015 Aug;90(8):1125-30. doi: 10.1016/j.mayocp.2015.05.010. PMID: 26250728. Prasad M, Tweet MS, Hayes SN, Leng S, Liang JJ, Eleid MF, Gulati R, Vrtiska TJ. Prevalence of extracoronary vascular abnormalities and fibromuscular dysplasia in patients with spontaneous coronary artery dissection. Am J Cardiol. 2015 Jun 15;115(12):1672-7. doi: 10.1016/j.amjcard.2015.03.011. Epub 2015 Mar 23. PMID: 25929580. Goel K, Tweet M, Olson TM, Maleszewski JJ, Gulati R, Hayes SN. Familial spontaneous coronary artery dissection: evidence for genetic susceptibility. JAMA Intern Med. 2015 May;175(5):821-6. doi: 10.1001/jamainternmed.2014. PMID: 25798899. Liang JJ, Prasad M, Tweet MS, Hayes SN, Gulati R, Breen JF, Leng S, Vrtiska TJ. A novel application of CT angiography to detect extracoronary vascular abnormalities in patients with spontaneous coronary artery dissection. J Cardiovasc Comput Tomogr. 2014 May-Jun;8(3):189-97. doi: 10.1016/j.jcct.2014.02.001. Epub 2014 Apr 4. PMID: 24939067. Tweet MS, Hayes SN, Pitta SR, Simari RD, Lerman A, Lennon RJ, Gersh BJ, Khambatta S, Best PJ, Rihal CS, Gulati R. Clinical features, management, and prognosis of spontaneous coronary artery dissection. Circulation. 2012 Jul 31;126(5):579-88. doi: 10.1161/CIRCULATIONAHA.112. Epub 2012 Jul 16. PMID: 22800851. Tweet MS, Gulati R, Aase LA, Hayes SN. Spontaneous coronary artery dissection: a disease-specific, social networking community-initiated study. Mayo Clin Proc. 2011 Sep;86(9):845-50. doi: 10.4065/mcp.2011.0312. PMID: 21878595; PMCID: PMC3257995.   WANT TO WORK AT MAYO? EM Physicians: https://jobs.mayoclinic.org/emergencymedicine EM NP PAs: https://jobs.mayoclinic.org/em-nppa-jobs   Nursing/Techs/PAC: https://jobs.mayoclinic.org/Nursing-Emergency-Medicine EMTs/Paramedics: https://jobs.mayoclinic.org/ambulanceservice All groups above combined into one link: https://jobs.mayoclinic.org/EM-Jobs

With Sotiria Liori, Attikon University Hospital, National and Kapodistrian University of Athens - Greece and Julie De Backer, Ghent University Hospital - Belgium. In this episode, Sotiria Liori and Julie De Backer discuss heart failure in adult congenital heart disease patients — covering how congenital lesions and prior repairs shape epidemiology and mechanisms (ventricular remodeling, valvular and conduit dysfunction, arrhythmias), as well as clinical assessment with imaging, biomarkers, and hemodynamics. They outline management with guideline-directed therapy, rhythm considerations, indications for advanced therapies (MCS and transplant), and pregnancy counseling. The episode also highlights multidisciplinary care models and key evidence gaps. Proposed reading:  General Principles of Heart Failure Management in Adult Congenital Heart Disease. Tompkins R, Romfh A. Heart Failure Reviews. 2020;25(4):555-567. doi:10.1007/s10741-019-09895-x Chronic Heart Failure in Congenital Heart Disease: A Scientific Statement From the American Heart Association. Stout KK, Broberg CS, Book WM, et al. Circulation. 2016;133(8):770-801. doi:10.1161/CIR.0000000000000352. Relation Between New York Heart Association Functional Class and Objective Measures of Cardiopulmonary Exercise in Adults With Congenital Heart Disease. Das BB, Young ML, Niu J, et al. The American Journal of Cardiology. 2019;123(11):1868-1873. doi:10.1016/j.amjcard.2019.02.053.  Heart Failure and Patient-Reported Outcomes in Adults With Congenital Heart Disease from 15 Countries. Lu CW, Wang JK, Yang HL, Kovacs AH, et al; APPROACH‐IS consortium, the International Society for Adult Congenital Heart Disease (ISACHD) *.J Am Heart Assoc. 2022 May 3;11(9):e024993. doi: 10.1161/JAHA.121.024993. Epub 2022 Apr 26. Pharmacological Therapy in Adult Congenital Heart Disease: Growing Need, Yet Limited Evidence. Brida M, Diller GP, Nashat H, et al. European Heart Journal. 2019;40(13):1049-1056. doi:10.1093/eurheartj/ehy480. Advanced Heart Failure Therapies For Adults With Congenital Heart Disease: JACC State-of-the-Art Review. Givertz MM, DeFilippis EM, Landzberg MJ, et al. Journal of the American College of Cardiology. 2019;74(18):2295-2312.doi:10.1016/j.jacc.2019.09.004. A Review of Heart Transplantation for Adults With Congenital Heart Disease. McMahon A, McNamara J, Griffin M. Journal of Cardiothoracic and Vascular Anesthesia. 2021;35(3):752-762. doi:10.1053/j.jvca.2020.07.027. Heart Failure in Adult Congenital Heart Disease: From Advanced Therapies to End-of-Life Care. Crossland DS, Van De Bruaene A, Silversides CK, Hickey EJ, Roche SL. The Canadian Journal of Cardiology. 2019;35(12):1723-1739. doi:10.1016/j.cjca.2019.07.626. This 2025 HFA Cardio Talk podcast series is supported by Bayer AG in the form of an unrestricted financial support. The discussion has not been influenced in any way by its sponsor. 

Har ni massor av data, briljanta analytiker och ändå en känsla av att insikterna inte når fram? Du är inte ensam. I en tid där "datadrivet" är ledordet på allas läppar, glömmer vi ofta den viktigaste komponenten: kommunikationen. Att ha data är en sak. Att få en organisation att agera på den är något helt annat. I poddavsnitt 236 gästas Jonas Jaani av Ted Solomon från Ctrl Digital, vi pratar om just detta – data storytelling. Ted delar med sig av en konkret strategi för att omvandla komplexa analyser till övertygande berättelser som leder till faktisk förändring. Vad är Data Storytelling (och varför är det så svårt)? När experter gräver fram insikterna går det inte alltid samman med det skillset som krävs för att kommunicera dem. "Jag har varit i organisationer där det finns hur skarpa människor som helst… Men de har liksom fastnat i deras terminaler, i deras burkar som aldrig kommer ut i organisationen. För att det krävs ett annat skillset." Data storytelling är alltså bron mellan två olika världar: den tekniska analysen och den mänskliga kommunikationen. Börja inte med grafen – börja med affären Hur gör man då? Teds första poäng är att en bra databerättelse börjar långt innan du ens öppnat Excel eller ditt BI-verktyg. Den börjar med förarbetet. "En berättelse måste ha ett syfte. Den måste ha lite kontext… så handlar det om att förstå först och främst vad är businessen?" För att ta ett konkret exempel från e-handeln: tillväxt är oftast en funktion av två saker: Tillväxt = Antal kunder x genomsnittligt köp per kund Dessa kan i sin tur brytas ner i mindre "spakar" som trafik, konverteringsgrad, snittordervärde och köpfrekvens. Detta KPI-träd är dock inte berättelsen. Det är kartan. Berättelsen börjar när du ser vad som avviker. Var "blöder" ni? Varför tappar ni kunder efter första köpet? Den frågeställningen blir kärnan i din analys och din story. Aristoteles och AI: Teds 4-stegsmodell för en effektiv databerättelse När du väl har din kärnfråga guidar Ted oss genom en tydlig struktur i fyra steg. Förarbetet: Hitta kärnfråganSom nämnt ovan: Förstå affären, identifiera era "spakar" (KPI:er) och lokalisera var det största problemet eller möjligheten finns. Detta ger dig syftet. Inledningen: Fånga publikenBörja inte med hur du gjorde analysen. Börja med varför. Ge kontext. Hur stort är problemet? Vad händer om vi inte löser det? Kvantifiera det gärna i kronor och ören. Detta skapar en intresseväckare och visar varför din analys är avgörande. Analysen: Kombinera Logos och PatosNu kommer vi till själva analysen. Här refererar Ted till Aristoteles gamla lära om retorik: Etos, Patos och Logos. Logos (Logik): Det här är dina siffror, dina grafer, den logiska kedjan som bevisar din poäng. Etos (Trovärdighet): Du bygger trovärdighet genom att vara transparent med dina metoder och avgränsningar. Patos (Känsla): Det här är nyckeln! Komplettera din kvantitativa data med kvalitativ. Istället för att bara säga "vi tappar 20% av kunderna" – visa ett exempel. "Det här är Anna. Hon köpte sin första produkt… varför kommer hon inte tillbaka?" Kanske har ni ett citat från kundtjänst som förklarar hennes frustration. Det gör siffrorna levande. Slutet: Konkreta åtgärder (den viktigaste delen!)Det vanligaste misstaget analytiker gör? De slutar efter analysen. De har förklarat problemet och känner sig klara. Men publiken lämnas med ett "Jaha?". Den viktigaste delen är slutet. Knyt ihop säcken, summera insikterna och – viktigast av allt – kom med tydliga rekommendationer och nästa steg. Vad föreslår du att ni ska göra? Och (bonuspoäng!) vad är den förväntade effekten (business impact) om ni genomför åtgärderna? Svaren blir billigare, men frågorna blir dyrare I en tid av AI, blir detta viktigare än någonsin. Ted är tydlig med att AI är ett fantastiskt verktyg, men det ersätter inte det kritiska tänkandet. "AI är all ära… men man kan inte abdikera sitt eget kritiska tänkande.

This week we review an episode from 3 years back and delve into the world of adult congenital heart disease when we review a recent work from the ACHD team at UCSF that assesses the impact of BMI on clinical outcomes in the single ventricle adult Fontan patient. What is the cause of elevation in BMI in some Fontan patients? Is obesity the only explanation? Is BMI a modifiable risk factor for our Fontan patients and should exercise be 'prescribed' for these patients? If so prescribed, what type of exercise is best for the Fontan patient? This week's work's senior author, Dr. Anushree Agarwal, Assistant Professor of Medicine at UCSF, shares her insights into this important topic. DOI: 10.1161/JAHA.122.026732Also mentioned in today's episode is episode #222 with Dr. Dan Halpern of NYU medical center (https://www.stitcher.com/show/pediheartpediatric-cardiology-today/episode/pediheart-podcast-222-impact-of-cardiac-rehab-on-exercise-tolerance-in-the-achd-patient-206781483)

Justin, Jaha, and Hannah discuss David Brooks' article about red states outpacing blue states in education. They also discuss James Talarico and Trump's Gaza deal.Show Notes: https://www.nytimes.com/2025/10/09/opinion/democrats-education-failure.html?smid=nytcore-ios-share&referringSource=articleShare https://www.politico.com/news/2025/08/21/james-talarico-miriam-adelson-billionaire-donations-00517288 https://www.bbc.com/news/articles/cj3yke64vp6o Learn more about your ad choices. Visit podcastchoices.com/adchoices

Jaha.

Justin and Jaha talk about Dr. Alan Noble's article on a post-literate culture and how that impacts Christian discernment. They also discuss Gaza and how AI data centers are raising energy costs for Americans.   Show Notes: What Does a Post-Literate Culture Look Like?  https://www.bloomberg.com/graphics/2025-ai-data-centers-electricity-prices/ https://www.cnn.com/world/live-news/israel-gaza-hamas-trump-10-05-25 Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this compelling episode of Vital Voices Live, Gambian women's rights activist Jaha Dukureh — a leading campaigner against female genital mutilation, founder and executive director of Safe Hands for Girls, TIME 100 honoree, and Nobel Peace Prize nominee — joins acclaimed actor and New York Times bestselling author Ashley Judd. Interviewed by actor and CARE Ambassador Bellamy Young, they explore the global fight to end female genital mutilation, the ongoing evolution of the #MeToo movement in Hollywood, and the power of personal stories to spark change for women and girls worldwide.

Jaha Zainabu is a storyteller. She writes poetry, fiction and musings. She has been a member of the Anansi Writers Workshop in Leimert Park since 1993. She is the author of eleven books of poetry and fiction. She travels throughout the United States sharing her work. In addition to being a writer she is also a visual artist. On this podcast she shares her journey and weighs in on a few hovering headlines.https://www.instagram.com/jaha0903/ https://www.instagram.com/diprimaradio/

Justin, Jaha, and Cory discuss the importance of taking unpopular positions when principles are at stake. They also talk about the Jimmy Kimmel debacle and shout out Memphis Mayor Paul Young. Show Notes: https://www.nbcnews.com/politics/congress/rand-paul-fcc-chair-comments-absolutely-inappropriate-jimmy-kimmel-rcna232703 https://youtu.be/u3IGa1mrCKQ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Justin, Cory, and Jaha discuss reactions to the assassination of Charlie Kirk. They also talk about a Christlike path forward.   Show Notes: https://www.nytimes.com/2025/09/14/opinion/charlie-kirk-assassination-ideology.html Learn more about your ad choices. Visit podcastchoices.com/adchoices

Today, Sam, Ryan, and Tyler talk about the mysterious city of Jaha! Join them as they talk about the city's strange origins, their relationship with the stars, and why you should make sure you stock up on coffee before visiting! Continuing the exploration of Golarion, the Campaign Setting for the Pathfinder Roleplaying Game by Paizo Inc. Website: TabletopTravelGuide.com   Email: TabletopTravelGuidePodcast@gmail.com     Instagram: @TabletopTravelGuide Patreon: Tabletop Travel Guide Podcast Theme Music By: Raymond Gramke

Jaha, är det inte ljudet så är det uppkopplingen. I veckans avsnitt introducerar vi lite fasta punkter som vi tänkt ska bli återkommande. Dessutom laggar Jörgens ADSL. Vi pratar också jakt och Tomas avslöjar att han jobbar extra som barista ute i skogen. Välkommen att lyssna.

In this special episode on Strategies for Staying Full and Satisfied, our host, Dr. Neil Skolnik will moderate a discussion with Lily Correa, registered dietitian about communicating strategies for staying full and satisfied. This special edition of Diabetes Core Update is sponsored by Avocados - Love One Today ®.    For more information, as well as diabetes-friendly mean plans and a free downloadable toolkit just go to:http://loveonetoday.com/SatisfiedEating Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Lilian (Lily) M. Correa, Lily Correa is a registered dietitian and diplomate of the American College of Lifestyle Medicine   Resources and References:   Henning, Susanne M. et al. Hass Avocado Inclusion in a Weight-Loss Diet Supported Weight Loss and Altered Gut Microbiota: A 12-Week Randomized, Parallel-Controlled Trial. Current Developments in Nutrition 2019, Volume 3, Issue 8, ISSN 2475-2991. https://doi.org/10.1093/cdn/nzz068.   Khan, Naiman A. et al. Avocado Consumption, Abdominal Adiposity, and Oral Glucose Tolerance Among Persons with Overweight and Obesity. The Journal of Nutrition 2021, Volume 151, Issue 9p2513-2521. https://doi.org/10.1093/jn/nxab187.   Lichtenstein, Alice H. et al. Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial. Journal of the American Heart Association 2022, Volume 11, Number 14. https://doi.org/10.1161/JAHA.122.02565.   Pacheco, Lorena S. et al. Effects of Different Allotments of Avocados on the Nutritional Status of Families: A Cluster Randomized Controlled Trial. Nutrients 2021, 13(11), 4021. https://doi.org/10.3390/nu13114021.   Senn, MacKenzie K. et al. Associations between avocado intake and measures of glucose and insulin homeostasis in Hispanic individuals with and without type 2 diabetes: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Nutrition, Metabolism and Cardiovascular Diseases 2023, Volume 33, Issue 12, 2428 – 2439. https://doi.org/10.1016/j.numecd.2023.08.002.   Wood, Alexis C. et al. Associations between Metabolomic Biomarkers of Avocado Intake and Glycemia in the Multi-Ethnic Study of Atherosclerosis. The Journal of Nutrition 2023, Volume 153, Issue 10, 2797 – 2807. https://doi.org/10.1016/j.tjnut.2023.07.013.   For more resources, research and recipes visit LoveOneToday.com/healthprofessionals.

Vidcast:  https://www.instagram.com/p/DN023UfWjJq/So-called “clear e-cigarettes that contain synthetic cooling agents trigger greater blood pressure and heart rate increases than menthol flavored e-cigarettes.  Yale and Boston University researchers issue this warning following their study of 200 young adult vapers and non-vapers.  They analyzed 3 groups: 23 clear-ecig vapers; 111 non-clear vapers; and 73 non-vapers. Their paper appears in the Journal of the American Heart Association.These “clear” vapes contain WS-23 or WS-3, both synthetic coolants that mimic menthol's cooling effects but impart no flavor to the vapor. The data revealed that these agents were associated with greater heart strains than e-cigs containing menthol itself. The investigators suggest that these synthetic cooling agents have been introduced to circumvent bans against flavorings in vaping products, such as the ones in Massachusetts, California, New York State, Delaware, and elect cities around the country,.While this study only looked at the short term effects of these synthetic cooling agents, it's not unreasonable to believe that “clear” e-cigs create greater risks of heart failure and stroke over time than other e-cigs. As usual..buyer beware.https://medicalxpress.com/news/2025-08-cigarettes-linked-greater-acute-blood.htmlhttps://www.ahajournals.org/doi/10.1161/JAHA.124.036106#ecigarettes #vaping #clear #cooling #menthol #hypertension #heartfailure #stroke 

John Mandrola discusses conduction system pacing vs standard pacing, withdrawing HF meds when AF is corrected and patient selection in LAAO. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Conduction System Pacing CSPACE trial https://doi.org/10.1016/j.jacc.2025.06.043 BLOCK HF trial https://www.nejm.org/doi/full/10.1056/NEJMoa1210356 BioPace trial https://doi.org/10.1093/europace/euaf029 II  Withdrawing Meds After AF Corrected WITHDRAW AF https://doi.org/10.1093/eurheartj/ehaf563 TRED HF https://pubmed.ncbi.nlm.nih.gov/30429050/ III Patient Selection in Left Atrial Appendage Occlusion Long-Term Outcomes Following LAAO in Medicare Beneficiaries: Outcomes From the National Cardiovascular Data Registry https://www.ahajournals.org/doi/10.1161/JAHA.124.039780 ESC Preview IV HTN Guidelines New Blood Pressure Guidelines: 4 Things I Like and 2 Concerns https://www.medscape.com/viewarticle/new-blood-pressure-guidelines-4-thing-i-and-2-concerns-2025a1000m1x You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Justin, Jaha, and Cory discuss the pressure people are under to act more progressive in academia and professional class circles. They also discuss mandatory mental health screenings for kids and Meta chatbots flirting with children.   Show Notes:  https://thehill.com/opinion/education/5446702-performative-virtue-signaling-has-become-a-threat-to-higher-ed/ https://www.cbsnews.com/chicago/news/gov-pritzker-signs-requiring-mental-health-screenings-schools/ https://www.thefp.com/p/abigail-shrier-stop-asking-kids-if https://mchb.hrsa.gov/sites/default/files/mchb/data-research/nsch-data-brief-adolescent-mental-behavioral-health-2023.pdf   Learn more about your ad choices. Visit podcastchoices.com/adchoices

I veckans avsnitt av Soffhjältarna pratas det om cyklopens återkomst till Marvel, Bautista som muskulös skurk och punkig spindelman. Peter har laddat om med nya Naked Gun, åkt snabb vroomvroom-bil med Brad Pitt och rånat loss med The Pickup. Dessutom … Fortsätt läsa →

Join our scientific team in the discussion of the 3 most clinically impactful papers of the month, the crème de la crème of our weekly top picks.This month we're discussing:Exploring safety of down-titrating diuretics in heart failure managementDOI: https://doi.org/10.1002/ejhf.3714Artificial Intelligence–Enabled ECGs for Atrial Fibrillation Identification and Enhanced Oral Anticoagulant Adoption: A Pragmatic Randomized Clinical TrialDOI: https://doi.org/10.1161/JAHA.125.042106Gradual Titration of Semaglutide Results in Better Treatment Adherence and Fewer Adverse Events: A Randomized Controlled Open-Label Pilot Study Examining a 16-Week Flexible Titration Regimen Versus Label-Recommended 8-Week Semaglutide Titration RegimenDOI: https://doi.org/10.2337/dc25-0690Scientific team:Ricardo Ladeiras Lopes, Mário Santos and João Sérgio NevesDiscover Medical Portfolio App weekly top picks - the latest and most relevant papers, curated by our team of experts! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/medicalportfolioapp⁠

Just talks to Cory and Jaha about eight political tribes in the American electorate. They also discuss Michael Wear's new article in UnHerd and Charlie Kirk's answer to a question about Trump and the fruit of the spirit. ShowNotes:https://echeloninsights.com/tribes/https://hiddentribes.us/https://unherd.com/2025/07/will-democrats-defend-society/?lang=ushttps://x.com/aprilspark1890/status/1950278328184619011?s=46&t=QIXD2eZx9xXe5eDxKKUDPg Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this Mission Matters episode, Adam Torres interviews Jaha Cummings, Founder of the Blanchard House Institute, on how his work blends economic revitalization, cultural preservation, and storytelling. Through initiatives like the American Dream Fund and Storyboard USA, Jaha empowers underinvested communities to reclaim their history and reshape their futures. This interview is part of the Milken Global Conference coverage by Mission Matters. Big thanks to the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Milken Institute⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for inviting us to cover the conference. Follow Adam on Instagram at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/askadamtorres/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for up to date information on book releases and tour schedule. Apply to be a guest on our podcast: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://missionmatters.lpages.co/podcastguest/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Visit our website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://missionmatters.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠More FREE content from Mission Matters here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/missionmattersmedia Learn more about your ad choices. Visit podcastchoices.com/adchoices

Approval of first-generation devices, the ticagrelor controversy, ICD longevity, the PRAGUE-25 trial (one of the most important trials of the year), and some thoughts on the end of EP as a profession are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I More Ticagrelor Controversy BMJ Investigation Finds More Concerns in Ticagrelor Trials https://www.medscape.com/viewarticle/investigation-bmj-raises-more-concerns-about-ticagrelor-2025a1000gh3 Ticagrelor PLATO study https://www.bmj.com/content/389/bmj.r1201 Ticagrelor vs Clopidogrel https://www.nejm.org/doi/full/10.1056/NEJMoa0904327 Review of the Ticagrelor Trials Evidence Base https://www.ahajournals.org/doi/10.1161/JAHA.123.031606 The Plato Trial: Do you believe in magic? https://doi.org/10.1093/eurheartj/ehp545 ONSET/OFFSET Antiplatelet Effects https://www.ahajournals.org/doi/10.1161/circulationaha.109.912550 RESPOND Study https://www.ahajournals.org/doi/10.1161/circulationaha.109.919456 II ICD Battery Longevity Variability in ICD Battery Longevity https://doi.org/10.1016/j.hrthm.2025.05.031 PRAGUE-25 Trial of AF Ablation vs LFM PRAGUE-25 Trial https://www.jacc.org/doi/10.1016/j.jacc.2025.04.042 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

In this thought-provoking episode of the ESVS Podcast we delve into an important and under-discussed issue in vascular surgery: Are women left behind in carotid stenosis treatment?Carotid stenosis is a contributor to ischemic strokes, and some papers show women may experience delays or suboptimal care in comparison to men. In this episode, we will listen to Professor Barbara Rantner, a senior consultant vascular surgeon from Munich, Germany, and Dr Claudia Schrimpf, a leading expert from Zurich, Switzerland. Together, they explore sex-related differences in carotid disease treatment and share their insights on the latest research and clinical experiences.Join us in this episode!References:Naylor R, Rantner B, Ancetti S, de Borst GJ, De Carlo M, Halliday A, Kakkos SK, Markus HS, McCabe DJH, Sillesen H, van den Berg JC, Vega de Ceniga M, Venermo MA, Vermassen FEG. European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery Disease. Eur J Vasc Endovasc Surg. 2023;65(1):7–111. doi:10.1016/j.ejvs.2022.04.011van Dam-Nolen DHK, van Egmond NCM, Koudstaal PJ, van der Lugt A, Bos D. Sex differences in carotid atherosclerosis: a systematic review and meta-analysis. Stroke. 2023;54(2):315–326. doi:10.1161/STROKEAHA.122.041046Skowronska M, Piorkowska A, Czlonkowska A. Differences in carotid artery atherosclerosis between men and women in the early phase after ischemic event. Neurol Neurochir Pol. 2018;52(1):35–40. doi:10.1016/j.pjnns.2017.09.002Schmid S, Tsantilas P, Knappich C, Kallmayer M, König T, Breitkreuz T, Zimmermann A, Kuehnl A, Eckstein H-H. Risk of in-hospital stroke or death is associated with age but not sex in patients treated with carotid endarterectomy for asymptomatic or symptomatic stenosis in routine practice: secondary data analysis of the nationwide German statutory quality assurance database from 2009 to 2014. J Am Heart Assoc. 2017;6(10):e004764. doi:10.1161/JAHA.116.004764Behrendt CA, Ten Bosch JA, Cronenwett JL, Dick F, Guekht A, Halliday A, et al. Sex-related differences in indication and procedural outcomes of carotid interventions in VASCUNET. Eur J Vasc Endovasc Surg. 2023;66(1):7–14. doi:10.1016/j.ejvs.2023.04.022

FDA approves triple-drug polypill, a change of opinion, a deep dive into invasive pulmonary embolism therapies, heart disease trends, and diabetes care is on fire are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I FDA News in HTN FDA announcement https://george-medicines.com/george-medicines-announces-fda-approval-of-widaplik-telmisartan-amlodipine-and-indapamide-a-new-single-pill-combination-treatment-for-hypertension-in-adults-including-initial-treatment/ Lancet Study https://doi.org/10.1016/S0140-6736(24)01744-6 JACC study vs placebo https://www.jacc.org/doi/abs/10.1016/j.jacc.2024.08.025 JAMA Cardiology Meta-analysis https://jamanetwork.com/journals/jamacardiology/fullarticle/2804313 II Invasive PE Therapy EHJ-Open review: https://academic.oup.com/ehjopen/article/5/3/oeaf071/8156689 PEITHO Trial https://www.nejm.org/doi/10.1056/NEJMoa1302097 REAL PE Observational Study https://pmc.ncbi.nlm.nih.gov/articles/PMC11308131/ III Heart Disease Trends King et al https://www.ahajournals.org/doi/10.1161/JAHA.124.038644 IV Diabetes Coverage Medscape Link https://www.medscape.com/viewcollection/37830 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Merita Jaha previews her work at Allentown Art Festival full 268 Fri, 13 Jun 2025 19:48:00 +0000 hBvihWQ0tf5yk4YeImiOe0EGs6dViqHZ news & politics,news WBEN Extras news & politics,news Merita Jaha previews her work at Allentown Art Festival Archive of various reports and news events 2024 © 2021 Audacy, Inc. News & Politics News False https://player.amperwavepodcasting.co

In this raw and riveting episode of People, Alpha Warrior sits down with actor, director, and cultural firebrand Isaiah Washington for an unfiltered look at a life shaped by trauma, triumph, and tenacity. From growing up poor in Houston without knowing it, to walking away from Hollywood deals with his integrity intact, Isaiah shares the unvarnished truth behind the headlines. He recounts his mother's resilience, the early days of navigating identity and poverty, and the moment he reclaimed his legacy through roles like Bass Reeves in Corsicana and Jaha in The 100. The conversation dives deep into race, representation, faith, censorship, and the manipulation of narrative in media and politics. Isaiah reflects on his time in the military, the shadowy workings of Hollywood, and the spiritual war behind the scenes. With stunning vulnerability and sharp wisdom, he calls for a return to legacy over success, truth over applause, and God over algorithms. This isn't a celebrity interview, it's a masterclass in resilience, redemption, and living on purpose. If you think you know Isaiah Washington, think again. This is the man behind the camera, behind the controversy, and behind the mission.

AI and ECGs, novel ways to treat hypertension, combined lipid-lowering therapy after myocardial infarction, PFA and silent stroke, a move toward accountability in AF ablation, and pacing issues in TTVR are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Help with ECGs in the ED AI Shows Promise for Rapid NSTEMI Diagnosis https://www.medscape.com/viewarticle/ai-shows-promise-rapid-nstemi-diagnosis-2025a10009pw Buscher et al https://doi.org/10.1093/eurheartj/ehaf254 II A Novel way to Treat HTN A Pacemaker to Control BP Gets FDA Breakthrough Designation https://www.medscape.com/viewarticle/pacemaker-control-bp-gets-fda-breakthrough-designation-2025a10009t3 JAHA paper https://www.ahajournals.org/doi/10.1161/JAHA.120.020492 Backbeat https://clinicaltrials.gov/study/NCT06059638 III Type of PFA may matter for Silent Cerebral Lesions Paper https://www.ahajournals.org/doi/10.1161/CIRCEP.125.013719 IV Accountability coming to US AF ablation Heart Rhythm Society Releases a Document on Establishing Centers of Excellence for AF ablation -- Press Release https://www.hrsonline.org/news/new-white-paper-on-atrial-fibrillation-centers-of-excellence/ V Pacing in Patients with Undergoing Transcatheter Tricuspid Valve Replacement Paper https://doi.org/10.1016/j.hrthm.2025.02.004 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-428 Overview: Stay ahead in stroke prevention with the latest guidelines. In this episode, we cover new considerations for social determinants of health, interventions across the lifespan, and evidence-based strategies to reduce stroke risk. Learn how to integrate these updates into primary care for more effective patient outcomes. Episode resource links: Bushnell, C., Kernan, W. N., Sharrief, A. Z., Chaturvedi, S., Cole, J. W., Cornwell, W. K., 3rd, Cosby-Gaither, C., Doyle, S., Goldstein, L. B., Lennon, O., Levine, D. A., Love, M., Miller, E., Nguyen-Huynh, M., Rasmussen-Winkler, J., Rexrode, K. M., Rosendale, N., Sarma, S., Shimbo, D., Simpkins, A. N., … Whelton, P. K. (2024). 2024 Guideline for the Primary Prevention of Stroke: A Guideline From the American Heart Association/American Stroke Association. Stroke, 55(12), e344–e424. https://doi.org/10.1161/STR.0000000000000475 Ravichandran, S., Gajjar, P., Walker, M. E., Prescott, B., Tsao, C. W., Jha, M., Rao, P., Miller, P., Larson, M. G., Vasan, R. S., Shah, R. V., Xanthakis, V., Lewis, G. D., & Nayor, M. (2024). Life's Essential 8 Cardiovascular Health Score and Cardiorespiratory Fitness in the Community. Journal of the American Heart Association, 13(9), e032944. https://doi.org/10.1161/JAHA.123.032944 Kumar, M., Orkaby, A., Tighe, C., Villareal, D. T., Billingsley, H., Nanna, M. G., Kwak, M. J., Rohant, N., Patel, S., Goyal, P., Hummel, S., Al-Malouf, C., Kolimas, A., Krishnaswami, A., Rich, M. W., Kirkpatrick, J., Damluji, A. A., Kuchel, G. A., Forman, D. E., & Alexander, K. P. (2023). Life's Essential 8: Optimizing Health in Older Adults. JACC. Advances, 2(7), 100560. https://doi.org/10.1016/j.jacadv.2023.100560 Life's Essential 8 tools for providers and patient information: https://www.heart.org/en/healthy-living/healthy-lifestyle/lifes-essential-8 Guest: Jill M. Terrien PhD, ANP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-428 Overview: Stay ahead in stroke prevention with the latest guidelines. In this episode, we cover new considerations for social determinants of health, interventions across the lifespan, and evidence-based strategies to reduce stroke risk. Learn how to integrate these updates into primary care for more effective patient outcomes. Episode resource links: Bushnell, C., Kernan, W. N., Sharrief, A. Z., Chaturvedi, S., Cole, J. W., Cornwell, W. K., 3rd, Cosby-Gaither, C., Doyle, S., Goldstein, L. B., Lennon, O., Levine, D. A., Love, M., Miller, E., Nguyen-Huynh, M., Rasmussen-Winkler, J., Rexrode, K. M., Rosendale, N., Sarma, S., Shimbo, D., Simpkins, A. N., … Whelton, P. K. (2024). 2024 Guideline for the Primary Prevention of Stroke: A Guideline From the American Heart Association/American Stroke Association. Stroke, 55(12), e344–e424. https://doi.org/10.1161/STR.0000000000000475 Ravichandran, S., Gajjar, P., Walker, M. E., Prescott, B., Tsao, C. W., Jha, M., Rao, P., Miller, P., Larson, M. G., Vasan, R. S., Shah, R. V., Xanthakis, V., Lewis, G. D., & Nayor, M. (2024). Life's Essential 8 Cardiovascular Health Score and Cardiorespiratory Fitness in the Community. Journal of the American Heart Association, 13(9), e032944. https://doi.org/10.1161/JAHA.123.032944 Kumar, M., Orkaby, A., Tighe, C., Villareal, D. T., Billingsley, H., Nanna, M. G., Kwak, M. J., Rohant, N., Patel, S., Goyal, P., Hummel, S., Al-Malouf, C., Kolimas, A., Krishnaswami, A., Rich, M. W., Kirkpatrick, J., Damluji, A. A., Kuchel, G. A., Forman, D. E., & Alexander, K. P. (2023). Life's Essential 8: Optimizing Health in Older Adults. JACC. Advances, 2(7), 100560. https://doi.org/10.1016/j.jacadv.2023.100560 Life's Essential 8 tools for providers and patient information: https://www.heart.org/en/healthy-living/healthy-lifestyle/lifes-essential-8 Guest: Jill M. Terrien PhD, ANP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com   

150 - What If Your Brain Fog Isn't All In Your Head? 7 Fixes You've Never TriedIf you've ever walked into a room and immediately forgotten why you're there, you'll want to hear this. What if your brain fog isn't just a coffee shortage… but a mitochondrial meltdown? In this episode of the Pretty Well Podcast, we're digging into the real root of brain health—your mitochondria. Yep, those tiny powerhouses are pulling more weight than you think. You'll learn 7 simple, science-backed ways to boost your brain clarity, energy, and focus (without adding 42 more supplements to your cart). If you're dealing with forgetfulness, low energy, or feeling like your brain's operating on dial-up, this one's for you. We're talking longevity, cognitive vitality, and how to keep your brain as sharp as your wit. Think of it as a tune-up for your brain; real ways to support long-term cognitive health so you can stay sharp, focused, and actually remember where you put your keys.Links & Resources:Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke; Arch Neurol. 2004;61(6):889-892. doi:10.1001/archneur.61.6.889https://jamanetwork.com/journals/jamaneurology/fullarticle/786017#google_vignetteEffects of Coenzyme Q10 on Statin‐Induced Myopathy: An Updated Meta‐Analysis of Randomized Controlled Trials; Journal of the American Heart AssociationVolume 7, Number 19 https://doi.org/10.1161/JAHA.118.009835 Amazon Links: *As An Amazon Associate I Earn A Small Commission From Qualifying Purchases At No Extra Cost To You*Pure Encapsulations Brand Mitochondria-Supporting Supplements:Magnesium Glycinate https://amzn.to/4iWlvhx Magnesium Citrate https://amzn.to/4ldRPy1 B complex Plus https://amzn.to/4lj1yTD B complex with PQQ and ALA https://amzn.to/4i3Kv54 CoQ 10 (active form Ubiquinol) https://amzn.to/4lisnHA Saccharomyces boulardii (probiotic) https://amzn.to/3DXc4zg Bellway Super Fiber: https://amzn.to/4i7Ud6B Nature's Sunshine Liquid Chlorophyll ES: https://amzn.to/42xQEly Epic Water Filter Products: https://amzn.to/42wOKSe Join the conversation: Share your thoughts with us on social media or in the comments!Subscribe, Share & Review: Remember to subscribe, share this episode, and leave a review. Your support helps us reach more women looking for answers.Disclaimer: Nothing in this podcast is to be taken as medical advice, please take informed accountability and speak to your provider before making changes to your health routine.The primary purpose of The Pretty Well Podcast being to educate. This content is for informational and educational purposes only. It is not intended to provide medical advice nor to take the place of such advice or treatment from a personal physician. By listening to this content, you agree to consult your own physician or qualified health professional regarding specific health questions. Neither Lisa Smith, The Pretty Well Podcast, nor any guest takes responsibility for possible health consequences of any person or persons following the information in this educational content. All listeners of this content, especially those who are pregnant or taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, or lifestyle program. The Pretty Well Podcast is for private non-commercial use and our guests do not necessarily reflect any agency, organization, or company that they work for. In addition, opinions of interview guests do not necessarily reflect the opinions of Lisa Smith and/or The Pretty Well Podcast. This content is not guaranteed to be correct, complete, or up to date.If you tune into any of the following shows, you'll like ours too! The Dr. Josh Axe Show, Wellness Mama, Be Well By Kelly Leveque, The Freely Rooted Podcast with Kori Meloy, The Dr. Mark Hyman Show, Dr. Jockers Functional Nutrition

In this episode, we discuss the very early stages of drug targets and drug development with Dr. Mohd Shahid, PhD. Dr. Shahid's research involves the IER3 gene, which is an important modulator of the body's inflammatory response via its action in major immune cells, including macrophages and T-cells, and plays a role in metabolic disorders such as obesity, diabetes, and atherosclerosis, revealing a previously unknown function of this protein. Key Concepts Drug development is a multi-decade journey – human clinical trials occur very late in the process. Drug development often starts before a drug molecule is even conceived by identifying potential drug targets. Chronic inflammation is important for a variety of diseases, including obesity and atherosclerosis. Dr. Shahid's work focuses on a specific gene, Immediate Early Response 3 Gene (IER3 or IEX-1), and its role in modulating the inflammatory response in these disease states. The research process frequently leads to unexpected discoveries and new lines of inquiry. With Dr. Shahid, his work in obesity and inflammation actually led to a new understanding of the IER3's role in the interplay between macrophages, inflammation, and energy expenditure. References Shahid M, Javed AA, Chandra D, et al. IER3 deficiency induces browning of white adipose tissue and resists diet-induced obesity. Sci Rep. 2016;6:24135. Published 2016 Apr 11. doi:10.1038/srep24135 Shahid M, Hermes EL, Chandra D, et al. J Am Heart Assoc. 2018;7:e009261. DOI: 10.1161/JAHA.118.009261. Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med. 2008;359(21):2195-2207. doi:10.1056/NEJMoa0807646 Tardif JC, Kouz S, Waters DD, et al. Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction. N Engl J Med. 2019;381(26):2497-2505. doi:10.1056/NEJMoa1912388

The goal of CPR is to keep the brain and vital organs perfused until return of spontaneous circulation (ROSC) is achieved.Post-arrest care and recovery are the final two links in the chain of survival.Identification of ROSC during CPR.Initial patient management goals after identifying ROSC.The patient's GCS/LOC should be evaluated to determine if targeted temperature management (TTM) is indicated.Patients that cannot obey simple commands should receive TTM for at least 24 hours.Recently published studies on TTM and ACLS's current standard.Monitoring the patient's core temperature during TTM.Patients can undergo EEG, CT, MRI, & PCI while receiving TTM.Good luck with your ACLS class!Links: Buy Me a Coffee at https://buymeacoffee.com/paultaylor Practice ECG rhythms at Dialed Medics - https://dialedmedics.com/Safe Meds VIP - Learn about medication safety and download a free drug discount card to save money on prescription medications for you and your pets: https://safemeds.vipPass ACLS Web Site - Episode archives & other ACLS-related podcasts: https://passacls.com@Pass-ACLS-Podcast on LinkedIn No statistical diff (TTM2 summary): https://www.ahajournals.org/doi/10.1161/JAHA.122.026539

Stopping oral anticoagulation after AF ablation, the core problem with paradoxes like the smoker's paradox, chronic total occlusion PCI, and an ACC/EHRA preview are discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Oral Anticoagulation after Successful AF Ablation Iwawakie et al https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831851 OCEAN protocol paper https://doi.org/10.1016/j.ahj.2017.12.007 II Smoker's Paradox Presch et al https://www.jacc.org/doi/10.1016/j.jcin.2024.12.028 Gupta et al https://doi.org/10.1161/JAHA.116.003370 III CTO PCI Main sub-analysis paper Bangalore et al https://doi.org/10.1016/j.jacc.2025.01.029 DECISION CTO https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.031313 Main EURO CTO trial https://doi.org/10.1093/eurheartj/ehy220 3-year MACE of EURO CTO https://eurointervention.pcronline.com/article/three-year-outcomes-of-eurocto-a-randomized-multicentre-trial-comparing-revascularization-and-optimal-medical-therapy-for-chronic-total-coronary-occlusions EXPLORE https://www.jacc.org/doi/abs/10.1016/j.jacc.2016.07.744 ISCHEMIA CTO https://www.clinicaltrials.gov/study/NCT03563417   IV ACC and EHRA Preview Mandrola's 5 Trials to Look for at the 2025 American College of Cardiology Scientific Sessions https://www.medscape.com/viewarticle/mandrolas-5-trials-look-2025-american-college-cardiology-2025a10006zu You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Kan man inte få blåsa skattebetalare på miljarder utan att få dumma jävla frågor!? Jaha, så kalvar föds utan hjärna nu? Toppen. Plus: Toms 5åring och John Ludvik hatar Kaj. Hosted on Acast. See acast.com/privacy for more information.

Silent cerebral embolism after LAAC, AI in ECG rhythm analysis, anti-thrombotic strategies in patients with AF and CAD, and subclinical AF are the topics John Mandrola, MD, covers in today's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Silent Cerebral Embolism after LAAC JAHA Case Series  https://www.ahajournals.org/doi/10.1161/JAHA.124.037968 JACC  https://doi.org/10.1016/j.jacc.2018.12.039 II. AI Transforming Rhythm Monitor Reading Johnson and colleagues RCT https://www.nature.com/articles/s41591-025-03516-x III. Anticoagulation Alone or OAC plus antiplatelets in patients with CAD and AF Rashedi and colleagues Meta-analysis https://doi.org/10.1016/j.jacc.2024.12.030 AQUATIC https://clinicaltrials.gov/study/NCT04217447 IV. DOAC for Subclinical AF – A Subgroup Analysis of ARTESIA Anticoagulation Uncertainty in Embolic Stroke of Undetermined Source https://www.medscape.com/viewarticle/anticoagulation-uncertainty-embolic-stroke-undetermined-2024a1000h5e Lancet Neurology Subgroup Analysis of ARTESIA 10.1016/S1474-4422(24)00475-7 ARTESIA https://www.nejm.org/doi/full/10.1056/NEJMoa2310234 NOAH https://www.nejm.org/doi/full/10.1056/NEJMoa2303062 RE-SPECT ESUS https://www.nejm.org/doi/full/10.1056/NEJMoa1813959 NAVIGATE ESUS https://www.nejm.org/doi/full/10.1056/NEJMoa1802686 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

In this week's replay episode from 2023, we speak with Associate Professor of Pediatrics at Mount Sinai, Dr. Jennifer Cohen about a recent large scale Fetal Heart Society project she conducted on the topic of fetal ccTGA and outcomes. What observations in fetal life are associated with worse clinical outcomes? Why is it valuable to perform serial fetal echocardiograms in this patient group? How common are genetic or extracardiac abnormalities in this patient group? These are amongst the many questions reviewed with Dr. Cohen this week. DOI: 10.1161/JAHA.122.029706

Wellness is big. But it really divides opinion. Some think of it as extreme aesthetic procedures or unnecessary fad diets whereas others regard it as essential maintenance.I explore what wellness really means in this episode.——Links:The GWI and wellness definitions: https://globalwellnessinstitute.org/Wellness vs wellbeing: https://www.gallup.com/workplace/340202/wellness-wellbeing-difference.aspxKelp and the thyroid: https://pmc.ncbi.nlm.nih.gov/articles/PMC6750240/When wellness goes wrong: https://www.theguardian.com/lifeandstyle/2024/mar/31/the-wellness-instagrammer-who-learned-to-let-goBBL: https://www.bbc.co.uk/news/uk-england-norfolk-66798236Gluten antibodies and neurological disease: https://www.sth.nhs.uk/news/2020/11/23/new-breakthrough-diagnostic-test-leads-to-earlier-detection-of-neurological-damage-caused-by-gluten-sensitivity/Stress and heart rhythm issues: https://www.ahajournals.org/doi/10.1161/JAHA.123.032414 Hosted on Acast. See acast.com/privacy for more information.

This week we review a recent large scale, multicenter adult congenital heart study on outcomes of HLHS Fontan patients versus other single RV Fontan patients. How do the two groups compare in regards to thromboembolic risk, risk for arrhythmia or risk for death and heart transplantation? Why might there be differences between these single RV patient groups? How can these results inform management? We speak with Assistant Professor of Medicine and Pediatrics at The Icahn School of Medicine at  Mount Sinai, ACHD expert Dr. Kali Hopkins. doi: 10.1161/JAHA.124.034757. Epub 2024 Nov 27

The topic of this podcast episode is the liver and its importance for bodily function. Nurse Doza emphasizes how common it is for people to have a fatty liver due to their diet, specifically fast food consumption. He explains how the sugar and fructose in these foods directly affect the liver and contribute to non-alcoholic fatty liver disease. He also encourages listeners to take control of their diet and make choices that support a healthy liver. This episode provides practical tips for improving liver health and acknowledges the positive impact the podcast is having on listeners' lives.   TIMESTAMPS: 00:00 START 06:20 The liver and its importance. 09:07 Non-alcoholic fatty liver disease. 12:09 Importance of food and nutrients. 15:44 Alcohol's contribution to diabetes. 21:46 Liver-supporting supplements. 23:05 Resveratrol in the Mediterranean diet. 29:38 Liver health and supplements. 32:45 Gut and liver relationship. 34:07 Fasting for a healthier liver. 37:22 Liver health practices. Introducing Liver Love: Every vibrant life begins with a healthy core. Cleanse, rejuvenate, and love your liver with our premium supplement, "Liver Love". Designed meticulously for Phase 1 and 2 of liver detoxing. Begin your journey to a healthier you. Click here to get Liver Love now! Show Notes:   The Importance of Supporting Antioxidant Production.[^1^] - The crux of health issues: Inflammation. - The origin of inflammation: Stress. - Consequences of chronic stress: Bodily dysfunction. - The liver: A powerhouse of antioxidant production[^2^]. - Glutathione: Liver's potent gift and its profound benefits[^3^]. - Introducing NAC: Glutathione's precursor and its significance[^4^]. - The need for NAC and glutathione supplementation. - The liver-enhancing power of B vitamins[^5^].   Hormone Regulation & The Liver[^6^] - The liver's pivotal role in hormone regulation. - The communicative power of hormones. - Liver: The body's natural storage facility. - Better hormones equate to a healthier liver[^7^]. - Early menopause's potential link to liver health[^8^]. - The underappreciated link: Liver and insulin. - The domino effect: Insulin issues leading to hormonal imbalances[^9^].   The Perils of Fast Food on Liver Health[^10^] - The challenges in processing fast food. - Residues of past unhealthy diets lingering in the liver. - Beyond fast food: The toll of an unhealthy diet on the liver[^11^]. - The equation of good fats and a healthier liver. - Avocado: The liver's best friend. - Monounsaturated fat: A top-tier dietary inclusion[^12^]. - The liver's role in cholesterol production[^13^]. - The promise of fish oil for liver wellness[^14^]. - The connection: Fatty liver, omega 3, and choline deficiencies[^15^].   Decoding the Relationship: Liver & Estrogen[^16^] - Fatty liver's association with compromised estrogen. - Estrogen production's direct tie to the liver[^17^]. - The toll of birth control on liver health and estrogen quality[^18^]. - The malleability of epigenetics[^19^]. - Stress, liver health, and its implications on estrogen[^20^]. - The genetic connection to liver health and detoxification needs[^21^]. - Delving into the COMT gene's role in hormone regulation[^22^]. - The intersection of cholesterol, liver, and menopause-associated estrogen[^23^].   Methylation & Its Influence on Liver Function[^24^] - The expression of the MTHFR gene in the liver. - Prevalence and implications of MTHFR gene mutation[^25^]. - The methylation cycle's role in vitamin metabolism[^26^]. - Significance of B9 in methylation and liver functions[^27^]. - The interconnected web: MTHFR gene's impact on various bodily processes[^28^]. - Glutathione production's link to correct methylation[^29^]. - Methylation's role in disease risk[^30^]. - The importance of methylated vitamins for MTHFR gene support[^31^]. - The intertwined roles of MTHFR and COMT genes in methylation[^32^]. Discover Liver Love: Let's face it, our livers undergo a lot, daily. Toxins, processed foods, medications, and more. It's time to give back. Show your liver some love with our specially formulated detox supplement, "Liver Love". The first step towards a healthier tomorrow starts with a cleanse today. Tap here to give your liver the love it deserves!   ---   **REFERENCES**:   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320789/figure/molecules-23-03305-f001/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637678/#B4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125908/ https://pubmed.ncbi.nlm.nih.gov/14973104/ https://pubmed.ncbi.nlm.nih.gov/19095062/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726297/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637678/ https://pubmed.ncbi.nlm.nih.gov/334126/ https://www.ahajournals.org/doi/10.1161/JAHA.120.020560 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228367/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123374/#MOESM3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674329/#R28 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531579/#B30

US doc's pay, the ticagrelor controversy and new RCTs, clopidogrel beats ASA, holding antiplatelets for non-cardiac surgery, and Prof Cleland and ASA dogma are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. US Healthcare Mandrola's Top 10 Stories in 2024 https://www.medscape.com/viewarticle/mandrolas-top-10-stories-2024-2024a1000mxe?_gl=1*dcvmkh*_gcl_au*MTgzOTY2ODQ0Ni4xNzI5MjU4NjUz CMS Proposal II. Ticagrelor Controversy New Investigation Casts Doubt on Landmark Ticagrelor Trial https://www.medscape.com/viewarticle/new-investigation-casts-doubt-landmark-ticagrelor-trial-2024a1000n1d Doshi Review https://www.bmj.com/content/387/bmj.q2550 PLATO https://www.nejm.org/doi/full/10.1056/NEJMoa0904327 ISAR REACT 5 https://www.nejm.org/doi/full/10.1056/NEJMoa1908973 Bates Review https://www.ahajournals.org/doi/epub/10.1161/JAHA.123.031606 Victor Serebuany and Dan Atar Editorial https://doi.org/10.1093/eurheartj/ehp545 III. New Ticagrelor vs Clopdiogrel trial Preprint: https://www.medrxiv.org/content/10.1101/2024.11.06.24316875v1.full-text IV. Clopidogrel Better Than ASA Even in HBR Substudy Long-Term Aspirin vs Clopidogrel After Coronary Stenting by Bleeding Risk and Procedural Complexity HOST-EXAM 10.1016/S0140-6736(21)01063-1 HOST-EXAM-Extended https://doi.org/10.1161/CIRCULATIONAHA.122.062770 V. ASA During Non-Cardiac Surgery ASSURE DES https://doi.org/10.1016/j.jacc.2024.08.024 VII. Professor Cleland on ASA for Secondary Prevention Cleland Editorial https//jamanetwork.com/journals/jamacardiology/article-abstract/2827201 ASA Meta-analysis 10.1016/S0140-6736(09)60503-1 AMIS https://jamanetwork.com/journals/jama/fullarticle/368745 SAPAT 10.1016/0140-6736(92)92619-Q You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Jaha.. då är vi i farten igen! Vi har typ ingen aning om vad vi pratar om. Det blir lite dirty jokes, nunnecamp, vi försöker lista ut vad the age of Aquarius är, Pumpkin day och The Boogie Man.Om ni vill malja oss med frågor, dilemman, tips på ämnen eller bara för att säga hej så kan ni nå oss på AlmostAmerikan@gmail.comFölj oss behind the mic på instagram @almostamerikanMusik gjord av: Fannie hertzberg & Joseph WilcoxOm du gillar avsnittet glöm inte att lämna 5 stjärnor ❤️ Hosted on Acast. See acast.com/privacy for more information.

Cardiologists Bob Harrington and Dhruv Kazi discuss the projected burden of cardiovascular disease in 2050, why it's not sustainable, and what can be done to prevent it. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington INCLUDE URLS and full titles for some of the pertinent studies cited. Forecasting the Burden of Cardiovascular Disease and Stroke in the United States Through 2050 https://doi.org/10.1161/CIR.0000000000001256 Forecasting the Economic Burden of Cardiovascular Disease and Stroke in the United States Through 2050 https://doi.org/10.1161/CIR.0000000000001258 Calculating the 30-day Survival Rate in Acute Myocardial Infarction: Should we Use the Treatment Chain or the Hospital Catchment Model? https://doi.org/10.5301/heartint.5000238 Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health https://doi.org/10.1161/CIR.0000000000001078 Current Trends in Hypertension Identification and Management: Insights from the National Health and Nutrition Examination Survey https://doi.org/10.1161/JAHA.123.034322 Youth-Onset Type 2 Diabetes: The Epidemiology of an Awakening Epidemic https://doi.org/10.2337/dci22-0046 US Trends in Cholesterol Screening, Lipid Levels, and Lipid‐Lowering Medication Use in US Adults, 1999 to 2018 https://doi.org/10.1161/JAHA.122.028205 GLP-1 Receptor Agonist Discontinuation Among Patients With Obesity and/or Type 2 Diabetes https://pubmed.ncbi.nlm.nih.gov/38787563 Health Care by Food https://healthcarexfood.org/ You may also like: Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

A new study published in the Journal of the American Heart Association explores the effects of extra virgin olive oil (EVOO) on cholesterol and heart health. Researchers found that both high and low usage of EVOO in the diet were linked to reductions in LDL-C, the "bad" cholesterol associated with heart disease. But during a 4-week carryover period, an interesting twist was revealed. Listen in this week as Dee discusses the results of the study, it's pros and cons, and how it could impact your health.Reference: Krenek, A. M., Mathews, A., Guo, J., Courville, A. B., Pepine, C. J., Chung, S. T., & Aggarwal, M. (2024). Recipe for heart health: A randomized crossover trial on cardiometabolic effects of extra virgin olive oil within a whole‐food plant‐based vegan diet. Journal of the American Heart Association, 13(15), e035034. https://www.ahajournals.org/doi/10.1161/JAHA.124.035034

The use of drug-coated balloons (DCBs) for peripheral arterial disease has been controversial in the past. However, new data and updated FDA guidance have helped these devices regain popularity. In this episode of the BackTable Podcast, Dr. Ally Baheti hosts a discussion with Dr. Sahil Parikh, an interventional cardiologist in New York City, and Dr. John Park, a vascular surgeon in Omaha. --- CHECK OUT OUR SPONSOR BD Lutonix https://www.bd.com/en-us/products-and-solutions/products/product-families/lutonix-drug-coated-balloon-pta-catheters --- SYNPOSIS They review the historical controversy surrounding the potential late-mortality risks associated with Paclitaxel-coated devices, discuss more recent literature on the safety and efficacy of DCBs, and examine the implications of the FDA's updated guidance in 2023. This update was made possible through collaborative efforts across specialties and regulatory bodies to establish best practices for vascular interventions. They also delve into patient selection criteria, lesion characteristics, and practical considerations for choosing between DCBs and other revascularization options. Each provider shares their treatment algorithm for DCB use in peripheral arterial disease. Dr. Park uses DCBs as a first-line treatment for patients with complete occlusions, CLTI symptoms, or lifestyle-limiting claudication, with adjunctive stenting sometimes required afterwards. In his experience, DCBs work best in lesions shorter than 100 mm and are preferable in locations where stenting is not feasible, such as across the knee joint. Dr. Parikh similarly prefers DCBs over plain balloon angioplasty and places stents in longer lesions. He notes that Hunter's canal is a challenging area to treat with DCBs alone and may require atherectomy or intravascular lithotripsy. He recommends considering drug-eluting stents as a proactive measure to prevent more costly interventions for future restenosis. --- TIMESTAMPS 00:00 - Introduction 02:14 - History of DCB and Controversy 07:46 - Updated Research and 2023 FDA Guidelines 16:44 - Importance of Collaboration and Patient Preference 26:34 - DCB Treatment Algorithms 33:31 - Drug-Eluting Stents 35:46 - Approach for Patients with Claudication 37:22 - DCB Sizing and Dose --- RESOURCES Risk of Death Following Application of Paclitaxel‐Coated Balloons and Stents in the Femoropopliteal Artery of the Leg: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials (2018): https://www.ahajournals.org/doi/10.1161/JAHA.118.011245 FDA- Treatment of Peripheral Arterial Disease with Paclitaxel-Coated Balloons and Paclitaxel-Eluting Stents Potentially Associated with Increased Mortality–Letter to Health Care Providers (2018): www.fda.gov/medical-devices/letters-health-care-providers/update-treatment-peripheral-arterial-disease-paclitaxel-coated-balloons-and-paclitaxel-eluting FDA- Paclitaxel-Coated Devices to Treat Peripheral Arterial Disease Unlikely to Increase Risk of Mortality - Letter to Health Care Providers (2023): https://www.fda.gov/medical-devices/letters-health-care-providers/update-paclitaxel-coated-devices-treat-peripheral-arterial-disease-unlikely-increase-risk-mortality Mortality in randomised controlled trials using paclitaxel-coated devices for femoropopliteal interventional procedures: an updated patient-level meta-analysis (2023): https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02189-X/abstract

Send us a Text Message.Placental Pathology Contributes to Impaired Volumetric Brain Development in Neonates With Congenital Heart Disease.Nijman M, van der Meeren LE, Nikkels PGJ, Stegeman R, Breur JMPJ, Jansen NJG, Ter Heide H, Steenhuis TJ, de Heus R, Bekker MN, Claessens NHP, Benders MJNL; CHD LifeSpan Study Group ‡.J Am Heart Assoc. 2024 Mar 5;13(5):e033189. doi: 10.1161/JAHA.123.033189. Epub 2024 Feb 29.PMID: 38420785 Free PMC article.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

This week we review a novel multivariable model used to predict mortality in the repaired tetralogy of Fallot patient. Can this model identify who amongst the repaired TOF patients is at risk for death in the coming years? What are the most important inputs to this model? Why does the use of a validation cohort provide greater strength to this model and is there still room for improvement in the model? Can the data in this work help inform decisions regarding pulmonary valve replacement timing? These are amongst the questions posed to the senior author of this work, Cardiologist-in-Chief at Boston Children's Hospital and Professor of Pediatrics at Harvard University, Dr. Tal Geva. Novel risk calculator: https://github.com/rTOF-INDICATOR/MORTALITY-RISK-Scoredoi: 10.1161/JAHA.123.034871. Epub 2024 Jun 11.

Posture is a hot topic online, tons of people are teaching you how to fix it and making money of explaining how to stand up straight. The science is more complicated than that, is there such thing as "good posture"? How do you know what is right for you and is there a way to fix your posture quickly?Studytime: how to fix your posture fastWDWLTW:empathy is contagiouswhy Ozempic may cure parkinsonsReferences:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166197/#:~:text=It%20is%20known%20that%20the,against%20injury%20or%20progressive%20deformity.https://pubmed.ncbi.nlm.nih.gov/19910263/https://pubmed.ncbi.nlm.nih.gov/27174256/https://pubmed.ncbi.nlm.nih.gov/33290371/https://pubmed.ncbi.nlm.nih.gov/29306972/#:~:text=Conclusion%3A%20This%20study%20did%20not,growing%20prevalence%20of%20neck%20pain.https://www.ahajournals.org/doi/10.1161/JAHA.123.031156https://today.ucsd.edu/story/sedentary-behavior-increases-mortality-riskhttps://www.jospt.org/doi/full/10.2519/jospt.2019.0610https://www.physio-pedia.com/Posture#cite_note-6https://pubmed.ncbi.nlm.nih.gov/16540876/https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-023-16617-4https://www.kineed.org/wp-content/uploads/2020/01/Thorvaldur-Skuli-Palsson-paper.pdfhttps://www.washingtonpost.com/wellness/2023/07/17/posture-devices-back-pain/ Hosted on Acast. See acast.com/privacy for more information.