Podcast appearances and mentions of David Baker

Dr David Baker's Nobel Prize-winning breakthrough of designing new proteins has the potential to stop cancers, pandemics, fix plastic pollution, and rein in carbon emissions. 

Today on the podcast... A food supplier to the supermarkets tells me the shocking way they make money, it’s so, so ruthless. Little wonder we are being ripped off. Plus, if you’re a builder, having a home built, or even planning on doing some DIY - you can’t miss these guys. They will call out the scams, the over-charging, and stop you from being screwed over. And some Letters to the Editor. Website: https://www.rova.nz/home/podcasts/duncan-garner---editor-in-chief. Instagram: @DuncanGarnerpodcast TikTok: @DuncanGarnerpodcast

David Baker, who was awarded the 2024 Nobel Prize in Chemistry for designing novel proteins with AI, is a professor at the University of Washington. In this episode, he explains how he socially engineers his lab's "communal brain", where all individuals function like neurons, densely interconnected to maximize idea generation. We explore the role of AI in science, discussing whether AI can be truly creative. Finally, we discuss the current funding crisis in science, which disproportionately affects young researchers.For more information about Night Science, visit https://www.biomedcentral.com/collections/night-science .

After 60 years of discussion, we may finally be making real, actionable plans to send a crew to Mars. One of the prime advocates for sending humans to the Red Planet has been Dr. Robert Zubrin, founder and president of The Mars Society. In 1990, he and David Baker worked up a plan called "Mars Direct," which took the core of then-current NASA planning and streamlined it into a more realistic, affordable approach. Since then, some of the key elements have been incorporated into NASA's Design Reference Missions, still the primary set of plans for reaching Mars. Join us for this fascinating discussion. Headlines Crew-9 Return: Astronauts Wilmore and Williams returned to Earth via SpaceX Dragon with dolphins swimming around their capsule—spoiler alert: it was NOT AI generated! Isar Aerospace: A German company prepared for the first orbital launch from Norway's Andoya Spaceport SpaceX Record: Achieved fastest booster turnaround yet by flying the same booster twice within nine days Main Topic: Mars Exploration with Dr. Robert Zubrin Mars Direct Plan: Zubrin's revolutionary 1990 proposal using just two heavy-lift launches and in-situ resource utilization, influencing NASA's planning Purpose vs. Vendor-Driven: Critique of NASA's Artemis as "vendor-driven" rather than focused on the mission goal Current Opportunity: New potential for Mars exploration under the current administration, but it must be a national program Timeline Prediction: Realistic goals of uncrewed Starship on Mars by 2028 and humans by 2033 Scientific Value: First Mars Starship should carry substantial scientific payload instead of just a demonstration mission—no red Tesla Roadsters to Mars, please Planetary Protection: Strong case against the "anti-human aesthetics" of keeping Mars pristine Science Budget Concerns: Warning against proposed 50% cuts to NASA's science programs Starboat Concept: Proposal for a smaller ascent vehicle to complement Starship for more efficient Mars and Moon missions Moon vs. Mars Strategy: Design hardware primarily for Mars that can also work for lunar exploration Hosts: Rod Pyle and Tariq Malik Guest: Dr. Robert Zubrin Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit

After 60 years of discussion, we may finally be making real, actionable plans to send a crew to Mars. One of the prime advocates for sending humans to the Red Planet has been Dr. Robert Zubrin, founder and president of The Mars Society. In 1990, he and David Baker worked up a plan called "Mars Direct," which took the core of then-current NASA planning and streamlined it into a more realistic, affordable approach. Since then, some of the key elements have been incorporated into NASA's Design Reference Missions, still the primary set of plans for reaching Mars. Join us for this fascinating discussion. Headlines Crew-9 Return: Astronauts Wilmore and Williams returned to Earth via SpaceX Dragon with dolphins swimming around their capsule—spoiler alert: it was NOT AI generated! Isar Aerospace: A German company prepared for the first orbital launch from Norway's Andoya Spaceport SpaceX Record: Achieved fastest booster turnaround yet by flying the same booster twice within nine days Main Topic: Mars Exploration with Dr. Robert Zubrin Mars Direct Plan: Zubrin's revolutionary 1990 proposal using just two heavy-lift launches and in-situ resource utilization, influencing NASA's planning Purpose vs. Vendor-Driven: Critique of NASA's Artemis as "vendor-driven" rather than focused on the mission goal Current Opportunity: New potential for Mars exploration under the current administration, but it must be a national program Timeline Prediction: Realistic goals of uncrewed Starship on Mars by 2028 and humans by 2033 Scientific Value: First Mars Starship should carry substantial scientific payload instead of just a demonstration mission—no red Tesla Roadsters to Mars, please Planetary Protection: Strong case against the "anti-human aesthetics" of keeping Mars pristine Science Budget Concerns: Warning against proposed 50% cuts to NASA's science programs Starboat Concept: Proposal for a smaller ascent vehicle to complement Starship for more efficient Mars and Moon missions Moon vs. Mars Strategy: Design hardware primarily for Mars that can also work for lunar exploration Hosts: Rod Pyle and Tariq Malik Guest: Dr. Robert Zubrin Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit

After 60 years of discussion, we may finally be making real, actionable plans to send a crew to Mars. One of the prime advocates for sending humans to the Red Planet has been Dr. Robert Zubrin, founder and president of The Mars Society. In 1990, he and David Baker worked up a plan called "Mars Direct," which took the core of then-current NASA planning and streamlined it into a more realistic, affordable approach. Since then, some of the key elements have been incorporated into NASA's Design Reference Missions, still the primary set of plans for reaching Mars. Join us for this fascinating discussion. Headlines Crew-9 Return: Astronauts Wilmore and Williams returned to Earth via SpaceX Dragon with dolphins swimming around their capsule—spoiler alert: it was NOT AI generated! Isar Aerospace: A German company prepared for the first orbital launch from Norway's Andoya Spaceport SpaceX Record: Achieved fastest booster turnaround yet by flying the same booster twice within nine days Main Topic: Mars Exploration with Dr. Robert Zubrin Mars Direct Plan: Zubrin's revolutionary 1990 proposal using just two heavy-lift launches and in-situ resource utilization, influencing NASA's planning Purpose vs. Vendor-Driven: Critique of NASA's Artemis as "vendor-driven" rather than focused on the mission goal Current Opportunity: New potential for Mars exploration under the current administration, but it must be a national program Timeline Prediction: Realistic goals of uncrewed Starship on Mars by 2028 and humans by 2033 Scientific Value: First Mars Starship should carry substantial scientific payload instead of just a demonstration mission—no red Tesla Roadsters to Mars, please Planetary Protection: Strong case against the "anti-human aesthetics" of keeping Mars pristine Science Budget Concerns: Warning against proposed 50% cuts to NASA's science programs Starboat Concept: Proposal for a smaller ascent vehicle to complement Starship for more efficient Mars and Moon missions Moon vs. Mars Strategy: Design hardware primarily for Mars that can also work for lunar exploration Hosts: Rod Pyle and Tariq Malik Guest: Dr. Robert Zubrin Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit

After 60 years of discussion, we may finally be making real, actionable plans to send a crew to Mars. One of the prime advocates for sending humans to the Red Planet has been Dr. Robert Zubrin, founder and president of The Mars Society. In 1990, he and David Baker worked up a plan called "Mars Direct," which took the core of then-current NASA planning and streamlined it into a more realistic, affordable approach. Since then, some of the key elements have been incorporated into NASA's Design Reference Missions, still the primary set of plans for reaching Mars. Join us for this fascinating discussion. Headlines Crew-9 Return: Astronauts Wilmore and Williams returned to Earth via SpaceX Dragon with dolphins swimming around their capsule—spoiler alert: it was NOT AI generated! Isar Aerospace: A German company prepared for the first orbital launch from Norway's Andoya Spaceport SpaceX Record: Achieved fastest booster turnaround yet by flying the same booster twice within nine days Main Topic: Mars Exploration with Dr. Robert Zubrin Mars Direct Plan: Zubrin's revolutionary 1990 proposal using just two heavy-lift launches and in-situ resource utilization, influencing NASA's planning Purpose vs. Vendor-Driven: Critique of NASA's Artemis as "vendor-driven" rather than focused on the mission goal Current Opportunity: New potential for Mars exploration under the current administration, but it must be a national program Timeline Prediction: Realistic goals of uncrewed Starship on Mars by 2028 and humans by 2033 Scientific Value: First Mars Starship should carry substantial scientific payload instead of just a demonstration mission—no red Tesla Roadsters to Mars, please Planetary Protection: Strong case against the "anti-human aesthetics" of keeping Mars pristine Science Budget Concerns: Warning against proposed 50% cuts to NASA's science programs Starboat Concept: Proposal for a smaller ascent vehicle to complement Starship for more efficient Mars and Moon missions Moon vs. Mars Strategy: Design hardware primarily for Mars that can also work for lunar exploration Hosts: Rod Pyle and Tariq Malik Guest: Dr. Robert Zubrin Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit

There are hidden costs in your construction business which could be killing your profits. David Baker, founder of RapidQS, joins us for another episode of The Builders Ladder podcast to share exactly why most builders are silently losing money on every project. After losing $2,500 on a $6,000 bathroom renovation early in his career, David discovered a key pricing element most building business owners overlook - properly accounting for time and management costs. In this episode, David shares: ✅Why sitting at your desk pricing jobs at night isn't "free time" - it's profit walking out the door ✅The exact “P&G” costs you must include on every quote (from site admin to vehicle charges) ✅How his company scaled from 2 jobs per week to 140 monthly by mastering these fundamentals ✅Why growth often means lower initial profits (and how to navigate this transition) Plus, discover RapidQS's journey from small local operation to international expansion. Including candid insights about the realities of scaling a construction-focused business. Key moments: 00:02:10 Beyond materials and labor00:03:20 New builds & small jobs00:06:00 Site protection costs 00:08:20 Losing money on jobs 00:13:30 Growth = smaller margins 00:18:30 What to focus on in tough times00:24:00 Create content to save time & energy00:30:50 The best partnerships Tune in for practical wisdom about pricing, leadership, and finding your "zone of genius" in a growing construction company. -

In honor of Rare Disease Day, we discuss news from Healx, a clinical-stage biotech, which has dosed the first patient in a Phase II trial of its new drug for neurofibromatosis type 1. In the world of AI, the Arc Institute in collaboration with Nvidia has dropped Evo 2, the “largest publicly accessible AI model for biology to date,” for designing genomes. Additionally, new work from Nobel Laureate, David Baker, uses AI to generate enzymes from scratch. We also dig into the big announcements from Illumina and Roche that got the community buzzing ahead of this year's AGBT meeting. Join GEN editors Corinna Singleman, PhD, Alex Philippidis, Fay Lin, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base: Healx Candidate, SpringWorks Therapy Expand NF1 Treatment OptionsBy Alex Philippidis, GEN Edge, February 25, 2025 Arc Institute's AI Model Evo 2 Designs the Genetic Code Across All Domains of Life By Fay Lin, PhD, GEN Edge, February 19, 2025 AI-Driven Protein Design Produces Enzyme that Mimics Natural Hydrolase Activity By Corinna Singleman, PhD, GEN, February 13, 2025 Illumina Unveils Spatial Technology Days Before AGBT Meeting By Julianna LeMieux, PhD, GEN, February 19, 2025 StockWatch: Illumina Tumbles on Q4 Results, China Retaliation By Alex Philippidis, GEN Edge, February 8, 2025 Roche Announces SBX Technology, Creates Sequencing Buzz By Julianna LeMieux, PhD, GEN, February 21, 2025 StockWatch: NIH Indirect Cost Cuts Shake Tools Stocks By Alex Philippidis, GEN Edge, February 17, 2025 Hosted on Acast. See acast.com/privacy for more information.

How would you react if a puck hit you in the face in the middle of a hockey broadcast? Also, the crew relives an awkward moment from Dan at this past weekend's South Beach Wine and Food Festival. Then, legendary college basketball coach Rick Barnes of the Tennessee Volunteers joins the show to discuss why he'd rather be at practice than talking with us, his love of NASCAR, the Yankees of his youth, and the Summer of '49. He also explains what he learned throughout his career from Bobby Knight, T.J. Ford, Richard Petty, and Kevin Durant before playing a game of Shot For Your Life. Plus, Patrick Willis joins the NFL Hall of Fame, Chris Cote has a great "looks like" for David Baker, and Roy has an Alexander Ovechkin Stat of the Day.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Life, Culture and Current Events from a Biblical perspective.Your support sends the gospel to every corner of Australia through broadcast, online and print media: https://vision.org.au/donateSee omnystudio.com/listener for privacy information.

Send us a textThe FTGN Merch Store is Live!! Help Support the site with official FTGN Gear!In this episode, Joe welcomes David Baker, former President & Executive Director of the Pro Football Hall of Fame, to explore leadership, legacy, and the values that shape extraordinary careers. David shares lessons from his time working with NFL legends, his deep respect for the military, and his latest mission to impact youth sports.Together, they discuss the key moments and insights that shaped his career, offering valuable takeaways for leaders in sports, business, and the military. David and Joe dive into:Why success isn't about a single job or title but about embracing the journey.Lessons in leadership from mentors like Jerry Jones, Roger Goodell, and Wellington Mara.The emotional power of "The Knock"—telling players they've been inducted into the Hall of Fame.How sports and the military share fundamental values like resilience, teamwork, and sacrifice.The importance of legacy—whether as a player, a leader, a parent, or a soldier.How his new initiative, World Youth Sports, aims to instill character and leadership in young athletes.Why every day matters, and how to make each one your masterpiece.Tune in to hear David's incredible stories and gain timeless leadership lessons that can help you build your own Hall of Fame-worthy legacy.A special thanks to this week's sponsors!Veteran-founded Adyton. Step into the next generation of equipment management with Log-E by Adyton. Whether you are doing monthly inventories or preparing for deployment, Log-E is your pocket property book, giving real-time visibility into equipment status and mission readiness. Learn more about how Log-E can revolutionize your property tracking process here!Exray a veteran-owned apparel brand elevating the custom gear experience. Exray provides free design services and creates dedicated web stores for units.Onebrief, the transformative software platform redefining operational planning and military staff workflows.

On this episode of the Kentucky Afield Podcast we're joined by Dave Baker, a fisheries biologist with The Kentucky Department of Fish and Wildlife Resources! Dave is extremely knowledgeable when it comes to both fish and fishing, as he's not only a professional in the field, but also an excellent angler as well... Here we're talking about all the exciting spring fishing opportunities that are on the horizon, including: White Bass, Crappie, Sauger, Walleye, Largemouth Bass, and Catfish! Get your rods and reels ready... It's just about time to go fishing!

Enjoy the first in our three-part series on the complete recordings of the late Alonzo “Pookie” Johnson, a legendary Indiana Avenue jazz saxophonist. This episode explores his early recordings.  Many local jazz fans consider Johnson to be one of the greatest saxophonists in Indianapolis history. During his six-decade career, Johnson performed with the greatest jazz players in Naptown, including Wes Montgomery, Slide Hampton, Jimmy Coe, Carl Perkins, Virgil Jones, David Baker, Errol Grandy, Freddie Hubbard, and many more.  Johnson was born in Indianapolis in October 1927. He studied music at Crispus Attucks High School, and the Jordan Conservatory. Johnson was a veteran of the Avenue club scene, performing at legendary venues such as the Sky Club, George's Bar, The P&P Club, Henri's, the Golden West, Sunset Terrace, and the British Lounge.

Ioannis Antonoglou, founding engineer at DeepMind and co-founder of ReflectionAI, has seen the triumphs of reinforcement learning firsthand. From AlphaGo to AlphaZero and MuZero, Ioannis has built the most powerful agents in the world. Ioannis breaks down key moments in AlphaGo's game against Lee Sodol (Moves 37 and 78), the importance of self-play and the impact of scale, reliability, planning and in-context learning as core factors that will unlock the next level of progress in AI. Hosted by: Stephanie Zhan and Sonya Huang, Sequoia Capital Mentioned in this episode: PPO: Proximal Policy Optimization algorithm developed by DeepMind in game environments. Also used by OpenAI for RLHF in ChatGPT. MuJoCo: Open source physics engine used to develop PPO Monte Carlo Tree Search: Heuristic search algorithm used in AlphaGo as well as video compression for YouTube and the self-driving system at Tesla AlphaZero: The DeepMind model that taught itself from scratch how to master the games of chess, shogi and Go MuZero: The DeepMind follow up to AlphaZero that mastered games without knowing the rules and able to plan winning strategies in unknown environments AlphaChem: Chemical Synthesis Planning with Tree Search and Deep Neural Network Policies DQN: Deep Q-Network, Introduced in 2013 paper, Playing Atari with Deep Reinforcement Learning AlphaFold: DeepMind model for predicting protein structures for which Demis Hassabis, John Jumper and David Baker won the 2024 Nobel Prize in Chemistry

A recent study in the journal Nature unveiled new proteins that can neutralize the deadliest of snake venoms. They're “new” in that they aren't found in nature—they were created in a lab, dreamed up by AI.Using AI to discover, or design, the building blocks of drugs is a fast-growing area of research. Another team of scientists out of Philadelphia is using AI to discover new antibiotics by resurrecting long-lost molecules from extinct species like neanderthals and woolly mammoths.We know what you're thinking: It sounds too sci-fi to be true.Flora Lichtman talks with two pioneers in the field about how AI is supercharging drug discovery: Dr. César de la Fuente, bioengineer and presidential associate professor at the University of Pennsylvania in Philadelphia, and Nobel laureate Dr. David Baker, director of the Institute for Protein Design and professor at the University of Washington in Seattle.Transcripts for each segment will be available after the show airs on sciencefriday.com.For our Los Angeles listeners: We're working on a story about the toxins left behind by the fires and we want to hear from you. How is this affecting you? Are you worried about the air and water and soil? How are you approaching clean-up? And what questions do you have?Leave us a voicemail at 1-646-767-6532 or send us an email at scifri@sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

This week on Data in Biotech, we welcome Timothy Jenkins, the Head of Data Science and Associate Professor at DTU Bioengineering, a leading scientific community dedicated to advancing areas of biotechnology, food technology, and health through innovative teaching and research.  Timothy starts the conversation by walking us through his background and early career beginnings, from the first time he expressed interest in zoology and venomous snakes to now leading a research group focused on AI-guided drug discovery for snake antivenom. He and our host, Ross Katz, dive into one of DTU's most exciting recent publications about "de novo" designed proteins to neutralize lethal snake venom toxins.  Inspired by Nobel Prize winner David Baker's groundbreaking paper and in collaboration with the Baker Lab on computational design methodology, this project holds great promise in therapeutic discovery and drug development. Tim explains how computational protein design and protein structure prediction are revolutionizing his field, highlighting compelling examples and milestones from his research on antivenom. He also provides an overview of the process used to discover new antivenoms, including the sourcing of biological data, model training, and integration of experimental feedback. Finally, we get Tim's perspective on the future of AI-powered therapeutic discovery, and his take on the integration of quantum computing into protein design. Data in Biotech is a fortnightly podcast exploring how companies leverage data innovation in the life sciences. Useful Links Nature - De novo designed proteins neutralize lethal snake venom toxins Timothy's LinkedIn DTU Bioengineering Website UW Institute for Protein Design “de novo” designed proteins project Information on Nobel Prize winner David Baker

Dr Chris Smith and the Naked Scientists look at the year ahead, and asking leading experts from the world of science what we can expect to hear about in 2025.Plus, a conversation with the 2024 chemistry Nobel laureate David Baker, about his pioneering working on proteins.

In light of Janis Stockhouse's unexpected death at the tail end of 2024, we're re-posting Kirk's 2019 interview with her for anyone who might want to listen to it.Janis started teaching at North high school in Bloomington, Indiana, in the early 1980s. It was a time when "jazz education" as a concept was still a relatively new thing. She retired 38 years later, having grown the North band program into a well-known Midwest institution, winning countless awards at festivals around the world and regularly turning out graduates who would go on to become professional musicians, as well as many others who would simply have a lifelong love of music.On this episode she tells the story of starting out at North and developing the program, along with her thoughts on how to get students to practice, which composers she prefers for student groups, women in jazz, funding for the arts, and some good old-fashioned album recommendations.REFERENCED ON THIS EPISODE:Janis's 2004 book Jazzwomen: Conversations With Twenty-One Musicians, which she co-wrote with Wayne Enstice - there are used copies on Amazon, and you should really track down a copy and read itThe late great jazz legend David Baker, whose NYT obituary captured at least some of his legacy: https://www.nytimes.com/2016/03/30/arts/music/david-baker-who-helped-bring-jazz-studies-into-the-academy-dies-at-84.htmlMUSIC ON THIS EPISODE:"IU Swing Machine" by David Baker as played by the 2016 IU Celebration Big Band"Don't Get Sassy" by the Thad Jones/Mel Lewis big band"Hang Gliding" by Maria Schneider from Alegresse"Bright Eyes" as played by the Bill Holman big band"Take the 'A' Train" by Billy Strayhorn as performed by the Duke Ellington orchestra"Vol. 6: All 'Bird' - Now's The Time" Play-A-Long by Jamey Aebersold (featuring Kenny Barron and Ron Carter(!!))"Laugh, Clown, Laugh" by Abbey Lincoln from Abbey Is Blue, 1959"Song Patrol" by Jane Ira Bloom from Early Americans, 2016"Lingala" by the SF Jazz Collective from their 2005 self-titled album"So What" and "Flamenco Sketches" by Miles Davis from Kind of Blue, 1959"My Favorite Things" as performed by John Coltrane on My Favorite Things, 1966"Mercy Mercy Mercy" by Josef Zawinul as performed by the Cannonball Adderley quintet on Mercy, Mercy, Mercy, 1966OUTRO SOLOIST: BJ CORDThis episode's outro soloist is BJ Cord, a fellow Bloomington North graduate and fantastic trumpet player based in Portland. BJ works at Monette trumpets making some of the most beautiful horns in the world, and is a regular presence on their Instagram: https://www.instagram.com/monettetrumpets

In this hour of VSiN PrimeTime, Mitch Moss, Pauly Howard, and Tim Murray preview Thursday Night Football. Plus, David Baker joins the show with more on the Seahawks-Bears game. See omnystudio.com/listener for privacy information.

Today's poem is Childhood by David Baker. The Slowdown is your daily poetry ritual. We're taking a break this week, so we're sharing some of our favorite episodes from the archive. We'll be back with new episodes on January 6, 2025. This episode was originally released on May 21, 2024. In this episode, Major writes… “I enjoy today's poem immensely for how it makes its opening comparison, then leads us to the sweet conclusion, one about an experience we all share. Yet, it individualizes through the power of metaphor.” Celebrate the power of poems with a gift to The Slowdown today. Every donation makes a difference: https://tinyurl.com/rjm4synp

PRL 1-6-25 Ellerbe, Alex Harper, Brian Bailey, John David Baker by Pirate Radio

Accusations of sabotage have been made after a Chinese merchant ship cut through two important undersea cables in the Baltic Sea. Eight of the nine states in the Baltic are members of NATO but Russia has access to the sea from St Petersburg and for its Kaliningrad exclave. With previous incidents of damage to underwater pipelines and cables, there's concern that the security of critical underwater infrastructure is at risk from ‘grey zone' activities - damaging but deniable incidents below the level of outright war. David Baker hears how countries' security is threatened by incidents like these. The pipelines that were cut ran between Finland and Germany and Sweden and Lithuania. He asks who can intervene to protect these assets in the Baltic. Can NATO respond?EXPERTS: Elizabeth Braw, a senior fellow at the Atlantic Council Scowcroft Centre for Strategy and Security, a thinktank based in Washington DC in the US and the author of an upcoming book called The Undersea War.Helga Kalm, director of the Lennart Meri Conference in Tallinn, Estonia, an annual meeting dedicated to international security and foreign affairs.Marion Messmer, senior research fellow in the International Security Programme at Chatham House, an international relations think tank in London, UK.Tormod Heier, a professor at the National Defence University College in Oslo, Norway and a former officer in the Norwegian Intelligence Service.CREDITS: Presenter - David Baker Producer - Philip Reevell. Researcher - Katie Morgan Editor - Tara McDermott Technical Producer - Craig BoardmanImage Credit - Rex/Shutterstock via BBC Images

Our Titans of Science season continues with the man who used AI to create an unprecedented number of custom proteins: Nobel Prize winning biochemist David Baker... Like this podcast? Please help us by supporting the Naked Scientists

Episode: 245 Released on December 16, 2024 Description:  Join us this week as we welcome a legend in law enforcement analysis, Jason's old friend and mentor, Joey Ryan! With a career spanning 15 years in analysis and another decade in law enforcement sales, Joey's story is a masterclass in turning passion into impact. From mapping crime hotspots in Maryland to reshaping the sales world, Joey's journey is filled with hilarious missteps, inspiring victories, and unfiltered wisdom.

Nathan welcomes back computational biochemist Amelie Schreiber for a fascinating update on AI's revolutionary impact in biology. In this episode of The Cognitive Revolution, we explore recent breakthroughs including AlphaFold3, ESM3, and new diffusion models transforming protein engineering and drug discovery. Join us for an insightful discussion about how AI is reshaping our understanding of molecular biology and making complex protein engineering tasks more accessible than ever before. Help shape our show by taking our quick listener survey at https://bit.ly/TurpentinePulse SPONSORS: Shopify: Shopify is the world's leading e-commerce platform, offering a market-leading checkout system and exclusive AI apps like Quikly. Nobody does selling better than Shopify. Get a $1 per month trial at https://shopify.com/cognitive SelectQuote: Finding the right life insurance shouldn't be another task you put off. SelectQuote compares top-rated policies to get you the best coverage at the right price. Even in our AI-driven world, protecting your family's future remains essential. Get your personalized quote at https://selectquote.com/cognitive Oracle Cloud Infrastructure (OCI): Oracle's next-generation cloud platform delivers blazing-fast AI and ML performance with 50% less for compute and 80% less for outbound networking compared to other cloud providers13. OCI powers industry leaders with secure infrastructure and application development capabilities. New U.S. customers can get their cloud bill cut in half by switching to OCI before December 31, 2024 at https://oracle.com/cognitive Weights & Biases RAG++: Advanced training for building production-ready RAG applications. Learn from experts to overcome LLM challenges, evaluate systematically, and integrate advanced features. Includes free Cohere credits. Visit https://wandb.me/cr to start the RAG++ course today. CHAPTERS: (00:00:00) Teaser (00:00:46) About the Episode (00:04:30) AI for Biology (00:07:14) David Baker's Impact (00:11:49) AlphaFold 3 & ESM3 (00:16:40) Protein Interaction Prediction (Part 1) (00:16:44) Sponsors: Shopify | SelectQuote (00:19:18) Protein Interaction Prediction (Part 2) (00:31:12) MSAs & Embeddings (Part 1) (00:32:32) Sponsors: Oracle Cloud Infrastructure (OCI) | Weights & Biases RAG++ (00:34:49) MSAs & Embeddings (Part 2) (00:35:57) Beyond Structure Prediction (00:51:13) Dynamics vs. Statics (00:57:24) In-Painting & Use Cases (00:59:48) Workflow & Platforms (01:06:45) Design Process & Success Rates (01:13:23) Ambition & Task Definition (01:19:25) New Models: PepFlow & GeoAB (01:28:23) Flow Matching vs. Diffusion (01:30:42) ESM3 & Multimodality (01:37:10) Summary & Future Directions (01:45:34) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://www.linkedin.com/in/nathanlabenz/ Youtube: https://www.youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431

Bailey Cichon, juggler and host of the podcast "The 441," joins the "ROI" team for episode #590 to discuss the history of juggling.The host for this edition is John Kealey, and the history buffs are Brett Monnard and David Baker.Opinions expressed in this program are those of the hosts and the guest(s), and not necessarily those of KALA-FM or St. Ambrose University. This program is recorded at KALA-FM, St. Ambrose University, Davenport, Iowa, USA!

BONUS DISCUSSION:  Bailey Cichon, juggler and host of the podcast "The 441," joins the "ROI" team for episode #590 to discuss the history of juggling.The host for this edition is John Kealey, and the history buffs are Brett Monnard and David Baker.Opinions expressed in this program are those of the hosts and the guest(s), and not necessarily those of KALA-FM or St. Ambrose University. This program is recorded at KALA-FM, St. Ambrose University, Davenport, Iowa, USA!

Ross Smith was eating chicken in the bath when he was shot dead by Malcolm Baker. Filled with wicked rage, Baker was on a violent killing spree, murdering his ex-girlfriend Kerryann Gannon and her pregnant sister Lisa Gannon, their father Thomas Gannon, his own son David Baker, as well as Ross' partner Leslie Read. Within 50 minutes, six lives had been stolen. Former detective Ted Bassingthwaighte unpacks the harrowing massacre that's rarely seen on Australian soil.   This episode of I Catch Killers discusses family violence. If this raises any issues or concerns, you can reach out to White Ribbon Australia on 1800RESPECT.   To buy a copy of the book, Bloody Odyssey, email Ted Bassingthwaighte directly, or find one here.   Can't get enough of I Catch Killers? Stay up to date on all the latest crime news at The Daily Telegraph. Get episodes of I Catch Killers a week early and ad-free, as well as bonus content, by subscribing to Crime X+ today. Like the show? Get more at icatchkillers.com.au Advertising enquiries: newspodcastssold@news.com.au  Questions for Gary: icatchkillers@news.com.au  Get in touch with the show by joining our Facebook group, and visiting us on Instagram or Tiktok.See omnystudio.com/listener for privacy information.

Terminamos nuestro repaso a los premios Nobel de ciencias, como siempre, con el galardón de Química, que este año ha sido todo lo contrario de una sorpresa. Se lo han llevado tres de los candidatos más firmes: David Baker, "por diseñar nuevas proteínas mediante ordenador", y Demis Hassabis y John Jumper, "por sus métodos para predecir la estructura tridimensional de las proteínas". Jumper y Hassabis son los responsables de que exista AlphaFold, una inteligencia artificial de la que hemos hablado más de una vez en La Brújula, y que fue la primera en predecir la forma tridimensional de una proteína a partir de su secuencia de aminoácidos. Esto ha supuesto una revolución para la bioquímica, porque la secuencia de aminoácidos de las proteínas podemos "leerlas" en el ADN, y gracias a programas como éste ahora podemos pasar de "la letra" a "el objeto". Baker, por su parte, es uno de los padres de las técnicas informáticas para el estudio de proteínas, y es responsable de RoseTTAFold, el "competidor" de AlphaFold, que aunque llegó un poco más tarde también está siendo parte de esta revolución. En el programa de hoy repasamos muy rápido la relevancia de estas investigaciones, pero si queréis aprender más sobre ellas podéis volver a escuchar los capítulos s08e16 y s10e17 de este pódcast. También podéis buscar el episodio s05e10 de nuestro pódcast hermano, Aparici en Órbita. En todos ellos os hablamos de estas inteligencias artificiales en mucho más detalle. Este programa se emitió originalmente el 9 de octubre de 2024. Podéis escuchar el resto de audios de La Brújula en la app de Onda Cero y en su web, ondacero.es

Aerospace giant Boeing has had big problems to overcome since the crashes of two of its 737 Max aircraft. Its situation was compounded this year with another safety scare and a strike losing it billions of dollars. It has a new CEO who has pledged to return the company to its engineering roots and away from cost cutting and in October, Boeing managed to raise 21bn US dollars by issuing new shares in the company. However, catching up on lost production will take time and money and financially the company is nowhere near out of the weeds.Can Boeing regain the trust of regulators, airlines and passengers? Contributors: Richard Aboulafia, AeroDynamic Advisory, a US aerospace consultancy Sharon Turlep, an aviation industry reporter at the Wall Street Journal Christine Negroni, an aviation journalist specialising in safety Scott Hamilton, aviation analystPresented by David Baker. Produced by Bob Howard. Researched by Matt Toulson. Edited by Tara McDermott. Mixed by David Crackles.

In this episode of FYI, ARK Chief Investment Strategist Dr. Charles Roberts and ARK Analyst Nemo Despot, PhD speak with David Baker, Nobel Prize-winning scientist and pioneer in protein engineering. Baker shares insights into his revolutionary work on Rosetta and the evolution of AI-driven protein design tools. With advances in technologies like RoseTTAFold and generative AI, he discusses how the field is moving towards designing proteins that can neutralize pathogens, catalyze chemical reactions, and potentially combat neurodegenerative diseases. Charlie and Nemo also examine the implications for healthcare, aging, and drug discovery as Baker envisions a future where synthetic biology and AI enable groundbreaking therapeutic options.Key Points From This Episode:Introduction of David Baker and his achievements in protein design and engineering.RoseTTAFold's evolution and its role in advancing protein structure prediction.How protein design could impact healthcare and the development of new therapies.The use of generative AI and diffusion models in protein design for medical applications.Challenges of modeling protein function and dynamics with current AI models.Potential of AI-designed proteins in applications like cancer therapy and neurodegenerative diseases.The role of multiomic research in understanding causality and improving drug efficacy.The implications of synthetic molecular machines for nanotechnology.Integrating computational and experimental methods in protein engineering.Future directions for protein design in therapeutic development, including custom protein-based solutions for disease.

David Baker, CFO of Elemental Altus Royalties, discusses the company's recent market performance, financial position, and growth strategies. He highlights positive market reactions following the recent acquisition of the AlphaStream portfolio, revenue projections for the upcoming years, and the challenges of navigating the royalty landscape amidst rising costs. Baker also emphasizes the importance of maintaining lean operations and the complexities involved in asset management and development.

Listen to the music of Quincy Jones and the masters of Indiana Avenue jazz. Quincy Jones was a legendary producer, musician, composer, and arranger. He died earlier this month at the age of 91.  Jones worked with many of the biggest stars in popular music, producing and arranging music for iconic performers, including Michael Jackson and Frank Sinatra. As a composer, Jones broke racial barriers in Hollywood, becoming one of the first Black musicians to score soundtracks for major films and television programs. During his historic career, Jones received many accolades, including 28 Grammys, an Emmy, a Tony, and seven Academy Award nominations. During his early years in music, Jones worked extensively, with musician from Indiana Avenue, including the Montgomery Brothers, Freddie Hubbard, David Baker, Pookie Johnson, Virgil Jones, J.J. Johnson, Carl Perkins, Leroy Vinnegar, and more. It's possible Jones himself played on the Avenue. From 1951 to 1953, Jones toured with the Lionel Hampton band as a trumpet player and arranger. During that time, the band played at Indiana Avenue's Sunset Terrace, on Thanksgiving Day of 1952. In the liner notes for the Wes Montgomery anthology “In the Beginning,” Jones recalled sleeping on Montgomery's floor when the Hampton band toured through Indianapolis.

In this hour of Cashing Out, Joe Ceraulo recaps the biggest stories coming out of week 9 in the NFL. Jordan Love shares an injury update after a tough loss against the Detroit Lions. Then, three-time World Series of Poker bracelet winner and 2020 Super Contest winner David Baker joins the show as we look ahead to the Baker Mayfield-Patrick Mahomes Monday Night Football matchup. Plus, Joe shares how he did on his Pick 6 this weekend. And, VSiN Senior Reporter Dave Tuley joins the show with a Circa Survivor update. See omnystudio.com/listener for privacy information.

I am a dad. That means I worry almost constantly about our kids. This week, I met two lovely people who made me worry a tiny bit less about how I am doing as a parent. You may have heard of Dr. David Baker. He’s a genius who works at UW on creating brand new proteins.  He was just awarded the Nobel Prize in Chemistry for his work. He’s a pretty big deal. What you may not have heard, is that long before he was a Nobel recipient, he was a kid in Seattle Public Schools. He went to Garfield High School and what was then Meany Junior High.

On Oct. 9, the 2024 Nobel Prize for Chemistry was awarded to David Baker, Demis Hassabis, and John M. Jumper for their work in prediction and design of protein structures. C&EN's executive editor for life sciences, Laura Howes, joins a special episode of Stereo Chemistry to discuss why the trio won, the significance of their work around proteins, and how she accurately predicted the win in C&EN's annual “Who Will Win?” webinar. Stereo Chemistry offers a deeper look at subjects from recent stories pulled from the pages of Chemical & Engineering News. Check out Laura's story on how these computational chemists won this year's Nobel Prize in Chemistry at cenm.ag/chemnobel2024.  

This is the audio of a presentation I gave at David Baker's MYOB conference in October 2024. In it I talk about 3 big fears that inhibit growth in your agency. Enjoy.

Interview with David Baker, CFO of Elemental Altus Royalties Corp.Our previous interview: https://www.cruxinvestor.com/posts/elemental-altus-royalties-tsxvele-poised-for-growth-and-flush-with-cash-5014Recording date: 17th October 2024Elemental Altus Royalties, a precious metals royalty company, has announced a strategic $28 million all-equity deal that significantly expands its portfolio and is expected to boost its revenue by 25% year-over-year. This transaction focused on consolidating royalties on the Bonikro mine and acquiring interests in 21 other exploration and development royalties, positions the company for substantial growth in the coming years.The deal's centerpiece is the increase of Elemental's royalty on the Bonikro mine from 2.25% to 4.5%, effectively doubling the quarterly payments from $1 million to $2 million. This consolidation of existing interests, coupled with the addition of new royalties, is projected to generate $6 million in revenue next year and $5 million annually over the next five years, based on consensus pricing. David Baker, CFO of Elemental Altus Royalties, emphasized the immediate impact of this acquisition, stating, "We're estimating it on consensus pricing, $6 million next year and then $5 million over the next five years just on consensus pricing. Obviously, fair bit lower than spot, so we've got full exposure to high gold price."The company now expects to generate over $30 million in revenue next year, marking a significant milestone in its growth trajectory. This revenue increase is particularly noteworthy given the current market conditions, where many junior miners are struggling to access capital. Elemental's ability to acquire royalties from cash-strapped juniors at attractive valuations presents a unique opportunity for growth.Investors should note that Elemental's portfolio is underpinned by high-quality, long-life assets. Nearly half of the company's revenue comes from two key royalties: Karlawinda, a large Australian gold mine, and Caserones, a significant copper mine in Chile. These assets provide a stable base of cash flow, supporting the company's growth initiatives and potential future acquisitions.The royalty business model offers investors exposure to precious metals with a lower risk profile compared to direct mining investments. Elemental's focus on gold and copper aligns well with current macro trends, including ongoing economic uncertainties driving interest in gold as a safe-haven asset and the global push towards clean energy and electrification supporting copper demand.Looking ahead, Elemental is well-positioned to leverage its growing cash flow for future acquisitions. The company's management has indicated openness to exploring streaming deals as it grows, potentially broadening its range of financing options for mining companies.From a valuation perspective, Baker suggests that the company may be undervalued based on projected cash flows: "If that translates to $20 million of recurring free cash flow, then you've got a precious metal royalty company trading at 10% free cash flow yield, which I feel like is a fair way off historical norms."For investors, Elemental Altus Royalties presents an opportunity to gain exposure to the precious metals sector through a company with a diversified portfolio, strong growth prospects, and a business model that benefits from market dislocations. However, as with any investment in the mining sector, investors should remain mindful of commodity price volatility and jurisdiction-specific risks associated with the company's royalty interests.As Elemental continues to execute its growth strategy and potentially explores new financing models, it could attract increased attention from both investors and larger players in a consolidating royalty sector, potentially offering additional value creation opportunities for shareholders.—View Elemental Altus Royalties' company profile: https://www.cruxinvestor.com/companies/elemental-altus-royaltiesSign up for Crux Investor: https://cruxinvestor.com

Evitar que un asteroide choque contra la Tierra es el objetivo de un proyecto conjunto de NASA y ESA. Hace dos años, la sonda DART impactó contra el asteroide Dimorphos para modificar su órbita alrededor de otra roca de mayor tamaño, Dydimos. Ahora, la misión Hera viaja rumbo al asteroide para estudiar a fondo los resultados de aquel impacto. Hemos entrevistado al catedrático de física de la universidad de Elche Adriano Campo Bagatin, participante en este proyecto. Esta semana ha sido la de los Nobel. El de Medicina o fisiología ha sido para los estadounidenses Victor Ambros y Gary Ruvkun por descubrir los microARNs, una diminuta clase de moléculas que constituyen un mecanismo esencial para controlar los genes. El de Física ha distinguido al estadounidense John J. Hopfield y al británico Geoffrey E. Hinton, pioneros de las redes neuronales que sentaron las bases de la Inteligencia Artificial. Y el de Química ha reconocido a los estadounidenses David Baker y John M. Jumper y al británico Demis Hassabis por aplicar la computación y la Inteligencia Artificial para conocer la estructura tridimensional de las proteínas a partir de la secuencia de sus aminoácidos y predecir cómo será esa estructura con la secuencia deseada. Verónica Fuentes nos ha informado que destaca la importancia de la genética en la longevidad, mayor que las dietas bajas en calorías. Álvaro Martínez del Pozo ha dedicado su sección a la bilivedina, una molécula derivada del catabolismo de la hemoglobina de la sangre, que proporciona el color verde a la bilis de los herbívoros, de las aves y de los animales de sangre fría. Con Fernando de Castro hemos hablado de la capacidad que tiene el cerebro para remodelarse y adaptarse a nuevas situaciones provocadas por traumas o enfermedades. El doctor Pedro Gargantilla nos ha explicado como el trasplante de órganos encuentra ecos sorprendentes en la mitología, donde dioses, héroes y criaturas fantásticas se enfrentan a la muerte a través de la renovación y el intercambio de partes del cuerpo. Escuchar audio

durée : 00:05:35 - Avec sciences - par : Alexandra Delbot - Les trois lauréats sont David Baker de l'Université de Washington, Demis Hassabis et John Jumper de Google DeepMind. Ce prix Nobel de chimie 2024 est scindé en deux. Il récompense à la fois des travaux sur la prédiction et sur la conception de la structure des protéines.

A Academia Real das Ciências da Suécia anunciou nesta quarta-feira (9) que os cientistas americanos David Baker e John Jumper e o britânico Demis Hassabis irão receber o Nobel de Química de 2024. Os laureados pela academia sueca para as áreas de física e medicina foram anunciados na segunda (7) e na terça-feira (8). O prêmio serve como uma vitrine para a produção em ciências desde 1901, mas a falta de diversidade entre os escolhidos levanta questões sobre as barreiras que existem na educação e nas carreiras científicas. O Durma com Essa conta as descobertas dos premiados e as críticas ao Nobel. O programa tem também Marcelo Montanini falando sobre a escolha de Gabriel Galípolo para comandar o Banco Central. Learn more about your ad choices. Visit megaphone.fm/adchoices

“I got the phone call and my wife promptly started screaming.” News of the 2024 Nobel Prize in Chemistry gave David Baker's household a very early wake up call. Here, just after the prize announcement, Baker speaks to the Nobel Prize's Adam Smith about the exciting potential of building brand new proteins, the inspirational effect his fellow laureates have had on his field and whether it is necessary to understand how predictive algorithms work. Hosted on Acast. See acast.com/privacy for more information.

Comprehensive coverage of the day's news with a focus on war and peace; social, environmental and economic justice. Hurricane Milton makes landfall in Florida as a Category 3 storm. The United Nations held briefings on the escalating crisis in the middle east as fighting in Gaza and Israel spreads to Lebanon. As the war in Gaza enters its second year, residents of the war-torn territory reflect on Hamas, its role in Gaza, and the cross-border attack the group launched last year that sparked the conflict. Nobel Prize in Chemistry awarded to David Baker, Demis Hassabis, and John Jumper for protein research UC healthcare, service workers rally statewide for higher wages, housing aid amid contract impasse. The post Hurricane Milton makes landfall in Florida as a Category 3 storm – October 9, 2024 appeared first on KPFA.

David Baker teilt sich den Preis mit Demis Hassabis and John Jumper für ihre Arbeit zur Vorhersage und Gestaltung von Proteinstrukturen mit künstlicher Intelligenz. Die ausgezeichneten Methoden haben großes Potential für Medizin und Materialforschung. Von Anneke Meyer

(Alleged) Pedophile David Hyles wrote a book called "Successful Church Youth Work" in 1976. In this episode, Sadie reads this book and gives us the lowdown. We also discuss the recent death by suicide of David Hyles' close associate, David Baker, whose death occurred days after he was arrested for sex crimes against a minor.WE HAVE NEW MERCH AVAILABLE, AND A NEW MERCH SHOP, at https://leavingedenpodcast.threadless.comStream the Leaving Eden Podcast theme song, Rolling River of Time on Spotify! https://open.spotify.com/artist/6lB7RwSQ9X5gnt1BDNugyS?si=jVhmqFfYRSiruRxekdLgKA.Join our Facebook Discussion group! https://www.facebook.com/groups/edenexodusJoin our subreddit! Reddit.com/r/EdenExodusInstagram:https://www.instagram.com/leavingedenpodcast/https://www.instagram.com/sadiecarpentermusic/https://www.instagram.com/gavrielhacohen/Twitter:https://twitter.com/HellYeahSadieFacebook:https://www.facebook.com/LeavingEdenPodcasthttps://www.facebook.com/GavrielHaCohen Get bonus content on Patreon Hosted on Acast. See acast.com/privacy for more information.

Content Warning: This podcast contains descriptions of abuse involving minors as well as descriptions of suicide, listener discretion is advised.On September 11, 2024, Pastor David Baker walked into the restroom of Maury Regional Medical Center and shot himself twice in the chest.After the shots were fired, the hospital went into lockdown, and hospital staff tried to save him, but his suicide attempt proved successful.To understand why this happened, you need to understand who David Baker was and the events that led up to this moment.✖️✖️✖️Support the Show: Patreon.com/PreacherBoys✖️✖️✖️If you or someone you know has experienced abuse, visit courage365.org/need-help✖️✖️✖️CONNECT WITH THE SHOW:preacherboyspodcast.comhttps://www.youtube.com/@PreacherBoyshttps://www.facebook.com/preacherboysdoc/https://twitter.com/preacherboysdochttps://www.instagram.com/preacherboyspodhttps://www.tiktok.com/@preacherboyspodTo connect with a community that shares the Preacher Boys Podcast's mission to expose abuse in the IFB, join the OFFICIAL Preacher Boys Facebook Group: https://www.facebook.com/groups/1403898676438188/✖️✖️✖️Sources & Clips Referenced:Let Us Prey Documentary: https://www.max.com/shows/let-us-prey-a-ministry-of-scandals/ca01f963-90fe-4028-9d3c-deb127d48f34Eddie Lapina x David Baker Interview: https://youtu.be/ejw0Ahc8veEDavid Baker on Modesty: https://x.com/BadSermons/status/1681000158635466752David Baker on Shiny Happy People: https://youtu.be/BZfH5suT9uMDavid Hyles Partnering with David Bakeer: https://youtu.be/y7PNis9G9FsDavid Baker for Mayor: https://youtu.be/y9DLydQoL0UDavid Baker sues mayoral candidate: https://www.columbiadailyherald.com/story/news/2022/07/25/mayoral-candidate-baker-subpoenas-rep-party-butt-defamation-suit/10052276002/David Baker loses election: https://www.columbiadailyherald.com/story/news/2022/08/04/maury-county-tn-mayor-election-results-sheila-butt-carlie-norman/10192331002/Restoration Care Ministries: https://youtu.be/CDWkzd9Qu_wBakers Arrest and Aftermath: https://fox17.com/news/local/affidavit-obtained-for-pastor-charged-with-sexual-battery-who-took-his-own-life-wednesday✖️✖️✖️The content presented in this video is for informational and educational purposes only. All individuals and entities discussed are presumed innocent until proven guilty through due legal process. The views and opinions expressed are those of the speakers.This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/PreacherBoys and get on your way to being your best self.Support this podcast at — https://redcircle.com/preacher-boys-podcast/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

This week we're breaking down “Stairmaggedon” and we hear from actor Leslie David Baker who played our favorite work-hating, pretzel-loving Stanley Hudson! Dwight is having the elevator repaired forcing everyone to use the stairs which is much to Stanley's dismay. Meanwhile Angela Martin tries to stand by the Senator and Nellie and Toby give Pam and Jim relationship advice. Director Matt Sohn also sends in audio clips about directing this episode, Angela makes Stanley's 3x5 drink for the Office Ladies team and Jenna breaks down the animal stacking scene with Paul Feig. So come celebrate that Kevin kept a secret so good and enjoy this episode!  Office Ladies Website - Submit a fan question: https://officeladies.com/submitaquestion  Follow Us on Instagram: OfficeLadiesPod To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices