Podcasts about organoids

Miniaturized and simplified version of an organ

  • 208PODCASTS
  • 486EPISODES
  • 37mAVG DURATION
  • 5WEEKLY NEW EPISODES
  • May 2, 2025LATEST
organoids

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Best podcasts about organoids

Latest podcast episodes about organoids

Winning the War on Cancer (Video)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Winning the War on Cancer (Video)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

Science (Video)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Science (Video)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

Astronomy (Video)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Astronomy (Video)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

Health and Medicine (Video)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Health and Medicine (Video)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

University of California Audio Podcasts (Audio)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

University of California Audio Podcasts (Audio)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

Health and Medicine (Audio)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Health and Medicine (Audio)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

Science (Audio)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Science (Audio)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

Astronomy (Audio)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Astronomy (Audio)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

UC San Diego (Audio)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

UC San Diego (Audio)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

Winning the War on Cancer (Audio)
Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)

Winning the War on Cancer (Audio)

Play Episode Listen Later May 2, 2025 72:39


Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people understand and value the life-changing discoveries in science. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Sandra Dillon Patient Advocate Alexander Khalessi, M.D., M.B.A. UC San Diego Jana Stoudemire Celestial Strategy, LLC Alysson Muotri, Ph.D. UC San Diego Rebecca Moores Philanthropist and Patient Advocate Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40519]

MOTHER-podcast with Karina Vazirova
Leah Hazard - Midwifery and The Future of Birth

MOTHER-podcast with Karina Vazirova

Play Episode Listen Later Apr 29, 2025 47:57


You can see how much society values women's health by the magnitude of the crisis in maternity care.Meet Leah Hazard, a practising midwife, activist, award-winning author, and mother of 2 daughters. Her book Womb: The Inside Story of Where We All Began is a vital investigation of the body's most miraculous and misunderstood organ. From smart tampons to womb transplants, trans healthcare to reproductive justice, she explores how the uterus affects us all as individuals and as a society. In this episode, we unpack why the health of mothers, midwives, and maternity systems tells us everything about the health of society at large. More from MOTHER:Subscribe to the newsletter: themotherverse.substack.comWant to create some magic together? Reach out to us: forms.gle/zfKWVCbw1ERKUgKB8Follow Leah:Website - leahhazard.co.ukWomb: The Inside Story of Where We All Began - amazon.co.uk/Womb-Inside-Story-Gripping-Statesman/dp/0349015805Bluesky - bsky.app/profile/leahhazard.bsky.socialInstagram - instagram.com/leahhazardSubstack - leahhazard.substack.com(00:00) Intro(01:10) The role of midwives in society(11:40) The difference between a midwife and a doula(13:00) What happens during labour(17:45) Uterus as a muscle(22:00) Birth Plans vs. Birth Preferences(26:30) Artificial wombs(35:40) Organoid placentas and endometrium(38:00) The uterine microbiome(43:40) Lessons about life, nature and the universe(45:10) Leah's Next Book: Birth Wars Hosted on Acast. See acast.com/privacy for more information.

Dr.Future Show, Live FUTURE TUESDAYS on KSCO 1080
110 - Future Now Show - Elizabeth April & The End Times Tunes, The Earth Generator, Yellowstone Caldera Cap Revealed, Human Consciousness and Aquatic Alien Biosignature, Sideways planet, Liver Organoids

Dr.Future Show, Live FUTURE TUESDAYS on KSCO 1080

Play Episode Listen Later Apr 24, 2025


Listen Now to 110 Future Now Show Much going on this week! Our fav psychic, millenial Elizabeth April, shares her predictions of the end of one era and the beginning of the next..spoiler alert..things will get worse then get great). With the passing of the Pope right after Easter, and the global upheavals connected to US politics, times, they are a’changing!  We have a rousing discussion on the shift in conciousnesws  needed for heaven on Earth, and look at new inventions that are arising from a more aware consciousness, such as abn electrical generator that runs purely on the Earth’s magnetic field. There a great story on an exo-planet, K2-18b, that appears to be a water world, with strong biosignature, suggesting life..we take a closer look. We also discuss the very weird finding of a planet found orbiting two stars at once, sideways!   Closer to home there is new info on the super volcano under Yellowstone and major progress towards growing a personal replacement live for those in need. Enjoy..  

Brain Inspired
BI 210 Dean Buonomano: Consciousness, Time, and Organotypic Dynamics

Brain Inspired

Play Episode Listen Later Apr 22, 2025 110:33


Dean Buonomano runs the Buonomano lab at UCLA. Dean was a guest on Brain Inspired way back on episode 18, where we talked about his book Your Brain is a Time Machine: The Neuroscience and Physics of Time, which details much of his thought and research about how centrally important time is for virtually everything we do, different conceptions of time in philosophy, and how how brains might tell time. That was almost 7 years ago, and his work on time and dynamics in computational neuroscience continues. One thing we discuss today, later in the episode, is his recent work using organotypic brain slices to test the idea that cortical circuits implement timing as a computational primitive it's something they do by they're very nature. Organotypic brain slices are between what I think of as traditional brain slices and full on organoids. Brain slices are extracted from an organism, and maintained in a brain-like fluid while you perform experiments on them. Organoids start with a small amount of cells that you the culture, and let them divide and grow and specialize, until you have a mass of cells that have grown into an organ of some sort, to then perform experiments on. Organotypic brain slices are extracted from an organism, like brain slices, but then also cultured for some time to let them settle back into some sort of near-homeostatic point - to them as close as you can to what they're like in the intact brain... then perform experiments on them. Dean and his colleagues use optigenetics to train their brain slices to predict the timing of the stimuli, and they find the populations of neurons do indeed learn to predict the timing of the stimuli, and that they exhibit replaying of those sequences similar to the replay seen in brain areas like the hippocampus. But, we begin our conversation talking about Dean's recent piece in The Transmitter, that I'll point to in the show notes, called The brain holds no exclusive rights on how to create intelligence. There he argues that modern AI is likely to continue its recent successes despite the ongoing divergence between AI and neuroscience. This is in contrast to what folks in NeuroAI believe. We then talk about his recent chapter with physicist Carlo Rovelli, titled Bridging the neuroscience and physics of time, in which Dean and Carlo examine where neuroscience and physics disagree and where they agree about the nature of time. Finally, we discuss Dean's thoughts on the integrated information theory of consciousness, or IIT. IIT has see a little controversy lately. Over 100 scientists, a large part of that group calling themselves IIT-Concerned, have expressed concern that IIT is actually unscientific. This has cause backlash and anti-backlash, and all sorts of fun expression from many interested people. Dean explains his own views about why he thinks IIT is not in the purview of science - namely that it doesn't play well with the existing ontology of what physics says about science. What I just said doesn't do justice to his arguments, which he articulates much better. Buonomano lab. Related papers The brain holds no exclusive rights on how to create intelligence. What makes a theory of consciousness unscientific? Ex vivo cortical circuits learn to predict and spontaneously replay temporal patterns. Bridging the neuroscience and physics of time. 0:00 - Intro 8:49 - AI doesn't need biology 17:52 - Time in physics and in neuroscience 34:04 - Integrated information theory 1:01:34 - Global neuronal workspace theory 1:07:46 - Organotypic slices and predictive processing 1:26:07 - Do brains actually measure time? David Robbe

HistoTalks: NSH Podcasts
Fixation on Histology Blog: Enhancing Organoid Research with Histogel-Based Embedding Techniques

HistoTalks: NSH Podcasts

Play Episode Listen Later Apr 11, 2025 4:17


Fixation on Histology Blog: Enhancing Organoid Research with Histogel-Based Embedding Techniques Based on an Article By: Havnar, C., Holokai, L., Ichikawa, R., Chen, W., Scherl, A., & Shamir, E. R. (2024) Click to read this post.

Ask Doctor Dawn
From NSAIDs and Lab Tests to Women's Health Revolution: Deep Diving into Menstruation Research, Hormone Studies, and Natural Remedies

Ask Doctor Dawn

Play Episode Listen Later Mar 30, 2025 56:54


Broadcast from KSQD, Santa Cruz on 3-27-2025: Dr. Dawn comments on how inappropriate conclusions of cause and effect lead to too many drugs being prescribed and incorrect claims of drug allergies. Dr. Dawn examines the risks of ibuprofen overuse, discussing how NSAIDs can damage the gut lining, affect kidney function, and lead to various health complications when used long-term. She provides insight into Medicare reimbursement rates for common lab tests, explaining the significant price disparities between Medicare payments and commercial rates. The show explores the current H5N1 bird flu situation affecting egg and dairy production, discussing viral mutations and the promising development of a universal flu vaccine. Dr. Dawn explores the remarkable fact that among placental mammals, only humans, certain bats, elephant shrews, and one species of spiny mouse experience menstruation, leading to challenges in research models. She recounts the fascinating history of menstruation research, from 1940s scientists chasing elephant shrews in South Africa to shipping bats in takeout containers for laboratory studies. The show details modern breakthroughs in menstruation research through organoids and organs-on-chips technology, explaining how these tools are revolutionizing our understanding of women's health. Dr. Dawn addresses perimenopause and hormone replacement therapy, discussing historical misconceptions and current treatment perspectives. The show concludes with research on artemisia, explaining how this traditional herb shows promise in treating polycystic ovary syndrome through its effects on hormone regulation.

The Future of Everything presented by Stanford Engineering

Physician Tina Stankovic is an ear, nose, and throat specialist and a lover of music whose seemingly disparate pursuits — medicine and music — have led her to a groundbreaking career in hearing research. She recently worked with music legend Paul Simon during his well-publicized battle with hearing loss and he has become a vocal advocate for hearing research. New understandings and new approaches like regenerative medicine have put the once-impossible dream of hearing restoration within reach, Stankovic tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Konstantina M. StankovicStanford Researchers Assist Paul Simon with his Return to the StageInside the Stanford Initiative to Cure Hearing Loss: Cutting-Edge Science and InnovationConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Tina Stankovic, a professor of otolaryngology and neurosurgery at Stanford University.(00:03:36) Why Hearing LossWhat inspired Tina's lifelong journey into hearing science.(00:04:17) Treating Hearing LossLimits of current options and lack of FDA-approved therapies.(00:05:23) Causes of Hearing LossThe two main categories of hearing loss: conductive vs. sensorineural.(00:07:47) Inside the Inner EarThe complexity of the inner ear, and why diagnosis is so difficult.(00:09:22) Tinnitus & Hearing LossWhy ear damage can cause phantom sounds in the brain.(00:10:28) Emerging Technologies in Hearing ResearchNew technologies that are evolving treatment approaches.(00:15:19) Recreating the Ear in the LabChallenges the inner ear's unique composition pose to researchers.(00:20:02) AI Applications in Hearing DiagnosisThe ways AI is transforming diagnosis and genetic analysis.(00:21:31) Can Ears Regrow?Why humans don't regenerate ear cells—but mice might help.(00:23:55) Emotional & Social Toll of Hearing LossHow hearing loss can lead to isolation, stigma, and cognitive decline.(00:26:06) Born Deaf vs. Later Hearing LossExperiential differences between those with early and late hearing loss.(00:27:52) Paul Simon's Role and AdvocacyHow the artist got involved with Tina's work and the initiative at Stanford.(00:29:44) Protecting Your HearingBest practices for protecting your hearing.(00:33:21) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Data in Biotech
Organoids and Active Learning for Chronic Disease with Naren Tallapragada

Data in Biotech

Play Episode Listen Later Mar 5, 2025 50:25


In this episode of Data In Biotech, Ross Katz interviews Naren Tallapragada, CEO and Co-founder of Tessel Bio, about his background in electrical engineering and physics and how personal circumstances led to him pivoting his focus to enter biotech and start Tessel Bio. Naren breaks down Tessel Bio's unique approach to drug discovery, which involves "reverse engineering" chronic diseases. Instead of starting with a potential drug and testing its effects, they begin with a clear picture of the disease itself—specifically, how it appears and behaves in the body. A key part of their method is using human organoids—tiny, lab-grown versions of human tissues—to closely replicate real diseases and see how different treatments interact with them. This “small data” approach is made substantially more efficient with the addition of active learning. Join us for a fascinating conversation about Tessel Bio's approach to finding cures for chronic diseases that impact hundreds of thousands of people every day.  ​​What You'll Learn in This Episode: Naren's journey into biotech and personal motivationUnderstanding Tessel Bio's approach to drug discoveryThe role of organoids in disease modelingData gathering and target identification strategiesActive learning in drug discovery at Tessel Bio Connect with Our Guest: Sponsor: CorrDyn, a data consultancyFind out more about Tessel Bio Connect with Naren on LinkedIn Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode!

The Stem Cell Podcast
Ep. 289: “Heart-Forming Organoids” Featuring Dr. Robert Zweigerdt

The Stem Cell Podcast

Play Episode Listen Later Mar 4, 2025 86:43


Dr. Robert Zweigerdt is a Principal Investigator at Hannover Medical School, where his lab focuses on cardiac differentiation and the scalable culture of PSCs. He talks about regulating the lineage-specific differentiation of hPSCs and generating heart-forming organoids that mirror developmental cardiogenesis. He also discusses the importance of mentorship and the benefits of an international research group.

principal investigators organoids hannover medical school pscs
RARECast
A Rapid and Scalable Approach for Screening Personalized ASOs

RARECast

Play Episode Listen Later Feb 27, 2025 23:56


Organoids, three-dimensional cell models that can replicate an individual's organs, are valuable tools for testing medicines that might treat their illness. It can, however, take up to $10,000 and a year to grow organoids using conventional methods from patient-derived induced pluripotent stem cells. Researchers at Children's Mercy Kansas City's Genomic Medicine Center developed a way to do this from about $200 and in two to three weeks. We spoke to Scott Younger, director of disease gene engineering at Children Mercy Kansas City's Genomic Medicine Center, about the process, the test it ran to match three children with Duchenne muscular dystrophy to an antisense oligonucleotide therapy, and the potential impact this may have on developing customized therapies for people with rare genetic diseases.

Fringe Radio Network
Lab Grown Brains! - Happy Fools Podcast

Fringe Radio Network

Play Episode Listen Later Feb 26, 2025 56:07


In this episode, we explore the alarming development of lab-grown human brain tissue that is being harnessed to operate machinery, play video games, and potentially more. Researchers are pushing the boundaries of biotechnology by cultivating miniature, functional clusters of neurons capable of interfacing with external devices. We also delve into Orchestrated Objective Reduction (Orch-OR), a theory of consciousness proposing that self-awareness arises from quantum-level processes within neuronal microtubules. Together, these cutting-edge topics raise profound questions about the nature of intelligence, the ethics of creating and using living brain matter, and the very foundations of conscious experience.

The Stem Cell Podcast
Ep. 288: “Cerebellar Organoids” Featuring Dr. Giorgia Quadrato

The Stem Cell Podcast

Play Episode Listen Later Feb 18, 2025 82:28


Dr. Giorgia Quadrato is Assistant Professor of Stem Cell and Regenerative Medicine at the University of Southern California. Her research focuses on brain developmental and neural organoids. She talks about protocols for generating cerebellar organoids, including those with functional Purkinje cells. She also discusses a transcriptomic atlas of neural organoids and the stem cell research landscape in California.

MIB Agents OsteoBites
An Organoid-based Functional Precision Medicine Trial in Osteosarcoma (PREMOST)

MIB Agents OsteoBites

Play Episode Listen Later Feb 14, 2025 68:57


Alice Soragni, PhD shares information about PREMOST: an organoid-based functional PREcision Medicine trial in OSTeosarcoma (NCT06064682), a clinical trial that is studying the feasibility of using organoids for predicting drug response and guiding therapy in osteosarcoma.Patient-derived tumor organoids (PDTOs) are lab-grown replicas of tumors that closely resemble the original cancer in both structure and behavior. These models can be rapidly created from small samples obtained during biopsies or surgeries, allowing us to test their responses to different drugs in the lab. This makes them highly valuable for developing personalized treatment strategies, particularly in light of a growing body of evidence showing how PDTOs can in many cases accurately mimic clinical responses. The Soragni Lab has developed a unique platform to grow these organoids efficiently from osteosarcoma surgical samples. They can create these three-dimensional avatars without needing complicated cell sorting or lengthy lab procedures. This means they can start testing drugs and get results within a week of the surgery, a turnaround that is rapid enough to potentially be used in the future to help guide treatment decisions In a pilot study, they found that testing drugs on these organoids provided insights that closely matched the patients' actual clinical outcomes. Osteosarcoma organoids with low viability after neoadjuvant chemotherapy matched patients who experienced higher tumor cell death (necrosis) after treatment and long-term disease status. The lab also investigated responses of PDTOs from advanced, recurrent, and metastatic sarcomas and found that the viability of these organoids in the lab correlated with the time to the next treatment in patients. The data suggests that osteosarcoma organoids could help predict how well some treatments may work. Encouraged by these promising results, the Soragni Lab has initiated a clinical trial to further explore the use of PDTOs to predict osteosarcoma therapy responses. Dr. Soragni will describe the study design for this first-of-its-kind, organoid-based clinical trial in sarcoma.Alice Soragni, PhD, is an Associate Professor in the David Geffen School of Medicine at UCLA, and a member of the Jonsson Comprehensive Cancer Center. She has a Bachelor and Master of Science cum Laude from the University of Bologna, Italy, and a PhD from the ETH of Zuerich, Switzerland. Her laboratory couples basic research into mechanisms of disease to the development of novel therapeutic strategies. Her expertise lies in the development of tumor organoid models to investigate the biology of rare tumors such as osteosarcoma and perform screenings for functional precision medicine applications.

FYI - For Your Innovation
Replacing Animal Testing: Organoids And AI With Thomas Hartung

FYI - For Your Innovation

Play Episode Listen Later Jan 23, 2025 60:50


In this episode of FYI, Brett Winton and Nemo Marjanovic sit down with Professor Thomas Hartung, MD-PhD, a leading expert in biomedical innovation at Johns Hopkins Bloomberg School of Public Health. They explore how human organoids—3D organ proxies—are revolutionizing drug discovery and toxicology testing by reducing reliance on animal models. Professor Hartung explains how advancements in stem cell science, microfluidics, and artificial intelligence are converging to accelerate clinical trials, increase safety, and lower costs. The conversation also delves into the ethical considerations of biological computing, where organoids may one day aid in cognition and pattern recognition tasks. Key Points From This Episode:The limitations of animal testing in preclinical drug discovery.How human organoids replicate organ functionality, improving research accuracy.The role of stem cells and microfluidics in advancing organ-on-chip technology.The impact of AI and big data in analyzing organoid testing outcomes.Examples of pharmaceutical companies adopting human-based models.Discussion on rapid vaccine development during the COVID-19 pandemic.The potential for brain organoids in studying neurological diseases like autism and Alzheimer's.Speculation on the use of organoids in biological computing and sensors.Ethical challenges surrounding the development of self-aware organoids.

Best Medicine
6. Pain Management, Organoids, Prosthetic Leg Covers

Best Medicine

Play Episode Listen Later Dec 24, 2024 28:46


Joining Kiri this week is comedian Desiree Burch who explains the best ways to cope with pain following surgery. Dr Abdullah Khan engineers mini versions of human organs in a dish to enable more effective testing of new medical treatments, and Mark Williams shows off personalised prosthetic legs clad in anything from gold and flames to beer and the Welsh Flag.Best Medicine is your weekly dose of laughter, hope and incredible medicine. Award-winning comedian Kiri Pritchard-McLean is joined by a funny and fascinating panel of comedians, doctors, scientists, and historians to celebrate medicine's inspiring past, present and future. Each week, Kiri challenges a panel of medical experts and a comedian to make a case for what they think is 'the best medicine', and each guest champions anything from world-changing science or an obscure invention, to an every-day treatment, an uplifting worldview, an unsung hero or a futuristic cure. Whether it's origami surgical robots, life-changing pineapple UTI vaccines, Victorian scandal mags, denial, sleep, tiny beating organoid hearts, lifesaving stem cell transplants, gold poo donors or even crying - it's always something worth celebrating. Hosted by Kiri Pritchard-McLeanFeaturing: Desiree Burch, Dr Abdullah Khan and Dr Mark WilliamsWritten by Laura Claxton, Mel Owen, Kiri Pritchard-McLean, Nicky Roberts and Ben RowseProducers: Tashi Radha and Ben WorsfieldTheme tune composed by Andrew JonesA Large Time production for BBC Radio 4

Ask Doctor Dawn
From NSAIDs and Lab Tests to Women's Health Revolution: Deep Diving into Menstruation Research, Hormone Studies, and Natural Remedies

Ask Doctor Dawn

Play Episode Listen Later Dec 13, 2024


Broadcast from KSQD, Santa Cruz on 12-12-2024: Dr. Dawn examines the risks of ibuprofen overuse, discussing how NSAIDs can damage the gut lining, affect kidney function, and lead to various health complications when used long-term. She provides insight into Medicare reimbursement rates for common lab tests, explaining the significant price disparities between Medicare payments and commercial rates. The show explores the current H5N1 bird flu situation affecting egg and dairy production, discussing viral mutations and the promising development of a universal flu vaccine. Dr. Dawn explores the remarkable fact that among placental mammals, only humans, certain bats, elephant shrews, and one species of spiny mouse experience menstruation, leading to challenges in research models. She recounts the fascinating history of menstruation research, from 1940s scientists chasing elephant shrews in South Africa to shipping bats in takeout containers for laboratory studies. The show details modern breakthroughs in menstruation research through organoids and organs-on-chips technology, explaining how these tools are revolutionizing our understanding of women's health. Dr. Dawn addresses perimenopause and hormone replacement therapy, discussing historical misconceptions and current treatment perspectives. The show concludes with research on artemisia, explaining how this traditional herb shows promise in treating polycystic ovary syndrome through its effects on hormone regulation.

Einstein A Go-Go
Organoids, legumes and lambs

Einstein A Go-Go

Play Episode Listen Later Dec 3, 2024 49:11


What's the point of science if you can't communicate what you've discovered? This week Dr Shane spends time with four of Australia's FameLab finalists: early career scientists who present their original findings with just 3 minutes (and a prop)! Dr Clair Richards from the University of Technology Sydney expands on her work on preeclampsia and growing placental organoids, so that research can be conducted without further risk to mothers or their babies. Murdoch University animal production scientist, Georgia Welsh discusses her work on winter lambing management by providing different feed and shelter options. Auriane Drack, a PhD candidate at the University of Melbourne and Baker Heart and Diabetes Institute, shares her work navigating the complexities of treating heart disease.Finally, FameLab 2024 winner and PhD candidate Johannes Debler from Curtin University and the Centre for Crop and Disease Management discusses the arms-race between fungus and many of the legumes that are critical part of our agriculture.Program page: Einstein-A-Go-GoFacebook page: Einstein-A-Go-GoTwitter: Einstein-A-Go-Go

Diffusion Science radio
Stem Cells and the Organoids

Diffusion Science radio

Play Episode Listen Later Oct 27, 2024


From 2014 listen to Professor Michael Morris on investigating the basic science of embryology to find out how embryonic stem cells become all other cells. 2024 news of the Internet Archive is down, and AI clones report the news with unexpected Organoids. From 2014 Crocodiles climb, and use tools, while alligators make video Hosted and produced by Ian Woolf Support Diffusion by making a contribution Support Diffusion by buying Merchandise

Two Scientists Walk Into a Bar
S5E07: Organoids: From Dish to Discovery

Two Scientists Walk Into a Bar

Play Episode Listen Later Sep 25, 2024 39:44


Did you know that scientists can grow three-dimensional, miniature versions of human organs in a dish? These tiny in vitro models, known as organoids, are helping scientists to better understand human disease and to test new treatments. In this episode, co-host Danielle Mandikian sits down with Kim Homan, Senior Director and Distinguished Scientist, Complex in vitro Systems Lab, to discuss the fascinating world of organoids and organ-on-chip technologies. They delve into how these systems are transforming drug development, where AI and ML come into play, and how organoid models could lead to more accurate predictions, better clinical studies, and improved patient outcomes. Read the full text transcript at www.gene.com/stories/organoids-from-dish-to-discovery

Huberman Lab
Dr. Victor Carrión: How to Heal From Post-Traumatic Stress Disorder (PTSD)

Huberman Lab

Play Episode Listen Later Sep 23, 2024 146:58


In this episode, my guest is Dr. Victor Carrión, M.D., the Vice-Chair of Psychiatry and Behavioral Sciences at Stanford School of Medicine and a world expert on the understanding and treatment of post-traumatic stress disorder (PTSD) in children, adolescents, and adults. We explain why, as children, we are particularly vulnerable to PTSD and how stress and trauma affect the developing brain. We also discuss how PTSD is related to attention-deficient hyperactivity disorder (ADHD) and vice versa. Dr. Carrión shares effective therapeutic interventions for PTSD, including cue-centered therapy (CCT) and how to create a custom “toolbox” to help you identify triggers and manage stress. We discuss an emerging curriculum that combines yoga and mindfulness to help people with PTSD improve their stress resilience, mood, and sleep. The episode will provide listeners of all ages with a clear understanding of PTSD and effective strategies to heal from it. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman  BetterHelp: https://betterhelp.com/huberman Waking Up: https://wakingup.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Dr. Victor Carrión 00:01:56 Sponsors: Eight Sleep, BetterHelp & Waking Up 00:06:19 Stress, Post-Traumatic Stress Disorder (PTSD), Avoidance 00:11:41 Stressors, Perseverate; Children & PTSD 00:16:13 Transgenerational Trauma 00:19:20 Post-Traumatic Stress Injury (PTSI); Children, Dissociation & Cortisol 00:27:17 Cortisol & Brain, Post-Traumatic Stress Symptoms 00:31:48 Sponsor: AG1 00:33:19 PTSD, Attention Deficit Hyperactivity Disorder (ADHD) 00:40:17 PTSD & ADHD; Identifying Cues, Triggers & Interventions 00:47:49 PTSI, Autonomic Nervous System Seesaw; Sleep 00:53:11 PTSD, Brain Development & Kids; Cue-Centered Therapy 01:02:37 Sponsor: Function 01:04:25 Limbic Pathway, Inner Dialogue, Therapy Toolbox 01:12:34 Agency & Control, Deliberate Cold Exposure, Narrative 01:18:11 Custom Toolbox Development; Energy 01:26:32 Tool: 4-Corner Square Response, Understanding Cues 01:32:59 Tool: “Creating Space,” Feelings Thermometer, Analyzing 4-Corners 01:38:47 Social Media, Boundaries 01:46:07 School, Yoga & Mindfulness Curriculum 01:55:31 Implementing School Mindfulness Programs, Sleep 02:00:52 Barriers to School Programs 02:06:08 Redefining Success, Identity 02:10:33 Resilience & Adaptation; Organoids, Epigenetic Treatment Response 02:21:42 Listening to Kids & Adults 02:24:19 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures

The AdGRodcast
Adgrodcast BONUS content: Brain Organoid

The AdGRodcast

Play Episode Listen Later Sep 6, 2024 16:44


We are oft fascinated by modern science and what it creates, and in this case, it's terrifying. Scientists are growing human brains in petri dishes to do computer processing because, yeah, the human brain is a wildly competent at processing multiple things. Did we stop to think about what would happen??? Of course not! We're humans, we are full of pride and hubris and we don't give a FUCK about consequences!! Anyhow, these little brain organoids might be alive, and apparently we're just okay with that.  WHEW. This song is about Rodney saving one of them from the clutches of misguided modern science.  And, it is a BONUS EPISODE to our loyal podcast fans.  Enjoy, and feel maybe just a little gross. 

The AdGRodcast
9/6/24 Adgrodcast: First thousandnaire, Emo Farts, Accidentally Cape Fear, Brain Organoid Trail, First to Clown College

The AdGRodcast

Play Episode Listen Later Sep 6, 2024 27:09


THIS WEEK!!!!  First and foremost, we are now streaming [some, maybe all?] episodes with visuals of us making the sausage in The Infamous Studio B, and that includes THIS EPISODE! For followers on our Podcasting streams, we still love you, and will also release every episode PLUS some bonus content to your Podcast feed.  Anyhow, we're doing tunes about Thousandaires, farts, Cape fear, Brain Organoids (which is a companion song to a BONUS episode also released with this one!), and also Clown College. Yeah. Which is where we obviously went. OBVIOUSLY. But for real, go check out Graham's newly yoked and cut-ass bod on YouTube. GET IT!   

Blood Podcast
Protective role of neonatal CMV infection in B-ALL; GVHD targets organoid-forming bile duct stem cells; seven-year outcomes for venetoclax-ibrutinib therapy in MCL

Blood Podcast

Play Episode Listen Later Aug 22, 2024 16:56


In this week's episode we'll learn how cytomegalovirus infection early in life depletes preleukemic cells in a mouse model of B-cell acute lymphoblastic leukemia. After that we'll discuss new research, where GVHD targets organoid-forming bile duct stem cells in a TGF-beta-dependent manner. Conversely, a TGF-beta inhibitor protects these stem cells against GVHD and mitigates biliary dysfunction. Finally, we'll hear about the seven-year outcomes for venetoclax-ibrutinib in relapsed or refractory mantle cell lymphoma. In addition to long-term survival benefits, researchers report durable treatment-free remissions and effective retreatment in patients with MRD-negative complete responses. Featured Articles: Early-life infection depletes preleukemic cells in a mouse model of hyperdiploid B-cell acute lymphoblasticleukemiaGVHD targets organoid-forming bile duct stem cells in a TGF-β–dependent mannerSeven-year outcomes of venetoclax-ibrutinib therapy in mantle cell lymphoma: durable responses andtreatment-free remissions

Science (Video)
Modeling Kidney Disease and Regeneration with Organoids Derived from Human Pluripotent Stem Cells

Science (Video)

Play Episode Listen Later Aug 5, 2024 56:20


Benjamin Freedman, Ph.D., delves into the creation and functionality of kidney organoids. He discusses their focus on filtration over hormone functions, and answer intriguing questions about urine characterization and the necessity of organoid structures. Freedman explores the use of scaffolds for implants and ponder the philosophical implications of off-target cells in organoids, questioning whether these cells are a natural part of organ development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39455]

Health and Medicine (Video)
Modeling Kidney Disease and Regeneration with Organoids Derived from Human Pluripotent Stem Cells

Health and Medicine (Video)

Play Episode Listen Later Aug 5, 2024 56:20


Benjamin Freedman, Ph.D., delves into the creation and functionality of kidney organoids. He discusses their focus on filtration over hormone functions, and answer intriguing questions about urine characterization and the necessity of organoid structures. Freedman explores the use of scaffolds for implants and ponder the philosophical implications of off-target cells in organoids, questioning whether these cells are a natural part of organ development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39455]

University of California Audio Podcasts (Audio)
Modeling Kidney Disease and Regeneration with Organoids Derived from Human Pluripotent Stem Cells

University of California Audio Podcasts (Audio)

Play Episode Listen Later Aug 5, 2024 56:20


Benjamin Freedman, Ph.D., delves into the creation and functionality of kidney organoids. He discusses their focus on filtration over hormone functions, and answer intriguing questions about urine characterization and the necessity of organoid structures. Freedman explores the use of scaffolds for implants and ponder the philosophical implications of off-target cells in organoids, questioning whether these cells are a natural part of organ development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39455]

Health and Medicine (Audio)
Modeling Kidney Disease and Regeneration with Organoids Derived from Human Pluripotent Stem Cells

Health and Medicine (Audio)

Play Episode Listen Later Aug 5, 2024 56:20


Benjamin Freedman, Ph.D., delves into the creation and functionality of kidney organoids. He discusses their focus on filtration over hormone functions, and answer intriguing questions about urine characterization and the necessity of organoid structures. Freedman explores the use of scaffolds for implants and ponder the philosophical implications of off-target cells in organoids, questioning whether these cells are a natural part of organ development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39455]

Science (Audio)
Modeling Kidney Disease and Regeneration with Organoids Derived from Human Pluripotent Stem Cells

Science (Audio)

Play Episode Listen Later Aug 5, 2024 56:20


Benjamin Freedman, Ph.D., delves into the creation and functionality of kidney organoids. He discusses their focus on filtration over hormone functions, and answer intriguing questions about urine characterization and the necessity of organoid structures. Freedman explores the use of scaffolds for implants and ponder the philosophical implications of off-target cells in organoids, questioning whether these cells are a natural part of organ development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39455]

KQ Morning Show
Grow Some Organoids!

KQ Morning Show

Play Episode Listen Later Jul 25, 2024 115:16


Originally aired on July 25, 2024: We are just about 5 years out from lab grown testicles, we debunk anti-sex beds at the Olympics and share your Nextdoor Nightmares. See omnystudio.com/listener for privacy information.

Round Table China
Chinese scientists develop brain-on chip organoid robot

Round Table China

Play Episode Listen Later Jul 17, 2024 24:43


Ever wished you could download knowledge directly into your brain like Neo in The Matrix? Well, we might not be quite there yet, but we're getting closer! Today's technology allows us to control a computer with just our thoughts and even operate a robot with a lab-grown human brain. Heyang, Yushun & Steve Hatherly

Mind Pump: Raw Fitness Truth
2378: How to Minimize Fat Gain When Reverse Dieting, the Truth About Exercise Snacks, Kickstarting Growth in Stubborn Arms & More

Mind Pump: Raw Fitness Truth

Play Episode Listen Later Jul 12, 2024 80:05


In this episode of Quah (Q & A), Sal, Adam & Justin answer four Pump Head questions drawn from last Sunday's Quah post on the @mindpumpmedia Instagram page.  Mind Pump Fit Tip: The exercise that you suck the most at is where all the gains are! (2:01) Adam's embarrassing bowling injury. (12:23) Putting the chicken nuggets from Butcher Box through the ultimate test! (19:35) I got my friends back! (24:14) When your AI clone goes dark. (29:30) Speculating on the future of education. (30:57) The human nature learning curve of adopting AI. (34:08) Cool technology. (42:37) Weighing the pros and cons of assisted suicide. (44:26) Making your property a cemetery. (49:23) USA's football blunder. (53:49) Is Pat McAfee a sore loser? (56:41) Shout out to the NCI x Mind Pump Tahoe Event! (59:44) #Quah question #1 - How do you determine that you have spent enough time building muscle and will have something to reveal once you go into a deficit? Do you base it on time spent building or weight gain or something else? (1:02:04) #Quah question #2 - Can you reverse diet after a show without putting on insane amounts of body fat? (1:06:39) #Quah question #3 - What's your take on exercise snacks? Besides pull-ups and pushups, what other exercises are great to do during your breaks? (1:10:15) #Quah question #4 - I've tried for 2 years to build the inner part of my bicep and nothing seems to work. When my arms are down to their sides, the part of the bicep that rests against my body looks awful! I work out 4x a week, and could lose 8-10 lbs. so nothing drastic…. I hate that part of my arms and I cover them up even in this heat. HELP! I want to go sleeveless! (1:14:20) Related Links/Products Mentioned Visit Butcher Box for this month's exclusive Mind Pump offer!  ** Your choice of bone-in chicken thighs, top sirloins, or salmon in every box for an entire year, plus get $20 off! ** Visit ZBiotics for an exclusive offer for Mind Pump listeners! ** Promo code MINDPUMP24 for 15% off first-time purchasers on either one-time purchases, (3, 6, 12-packs) or subscriptions (6, 12-pack) ** July Promotion: MAPS Split | Sexy Athlete Bundle 50% off! ** Code JULY50 at checkout ** Mind Pump #2145: Forgotten Muscle & Strength Building Secrets Mind Pump #1897: Why Phasing Your Workouts Is So Important & How To Properly Switch It Up The Importance of Incorporating Mobility Training to Avoid Injury Influencer Disturbed When Her “AI Clone” Starts Engaging in Dark Fantasies Alpha School China builds robot with lab-grown HUMAN BRAIN dubbed ‘Organoid' in Frankenstein experiment to create ‘hybrid machines' The Revolving Toilet by Sanitronics, a revolutionary self cleaning toilet, by Business Insider NATIONAL DISASTER: Japan Beats Team USA National Team In Football... HOW DID THIS HAPPEN?! Caitlin Clark SUES Pat Macafee NCI x Mind Pump 2 Day Truckee Experience Visit Seed for an exclusive offer for Mind Pump listeners! **Promo code 25MINDPUMP at checkout for 25% off your first month's supply of Seed's DS-01® Daily Synbiotic** The Most Overlooked Muscle Building Principle - Mind Pump Media Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Mark Sisson (@marksissonprimal) Instagram  

Canary Cry News Talk
JOE UNSTOPPABLE | Trump Epstein News, Organoids, Enchanted AI, Jews in Antarctica | CCNT 754

Canary Cry News Talk

Play Episode Listen Later Jul 4, 2024 141:53


BestPodcastintheMetaverse.com Canary Cry News Talk #753 07.03.2024 - Recorded Live to 1s and 0s JOE UNSTOPPABLE | Trump Epstein News, Organoids, Enchanted AI, Jews in Antarctica Deconstructing Corporate Mainstream Media News from a Biblical Worldview Declaring Jesus as Lord amidst the Fifth Generation War! TJT Youtube (backup) Channel: https://www.youtube.com/@TheJoyspiracyTheory The Show Operates on the Value 4 Value Model: http://CanaryCry.Support Join the Supply Drop: https://CanaryCrySupplyDrop.com                   Submit Articles: https://CanaryCry.Report Submit Art: https://CanaryCry.Art Join the T-Shirt Council: https://CanaryCryTShirtCouncil.com Podcasting 2.0: https://PodcastIndex.org Resource: Index of MSM Ownership (Harvard.edu) Resource: Aliens Demons Doc (feat. Dr. Heiser, Unseen Realm) Resource: False Christ: Will the Antichrist Claim to be the Jewish Messiah Tree of Links: https://CanaryCry.Party   Join the Canary Cry Roundtable This Episode was Produced By: Full Credit to Producers of Treasure in next episode CanaryCry.ART Submissions Marti K Knight fo the Wrong Timeline, Warrior of Yah TIMESTAMPERS Jade Bouncerson, Morgan E CanaryCry.Report Submissions JAM REMINDERS Clankoniphius   SHOW NOTES/TIMESTAMPS Podcast = T - 6:05 from rumble PreShow Prayer: Anthony H 6:05 V / 0:00 P HELLO, RUN DOWN 12:56 V / 6:51 P TRUMP 15:10 V / 9:05 P 'Before marrying Melania in 2005': What new documents claim (Time of India) HARRY LEGS 26:52 V / 20:47 P As Biden digs in, some top Democrats want him out of the race this week (CNN) → Pressure building on Biden to step aside. But Democrats feel powerless to replace him (AP) VALUE FOR VALUE FOR THE WIN! 1:01:03 V / 54:58 P FLIPPY 1:30:55 V / 1:24:50 P 'Brain-in-a-jar' biocomputers can now learn to control robots (NewAtlas) → First coverage of organoids and brain on chips in 2012, CCR 003 TRANSHUMAN 1:49:28 V / 1:43:23 P New Podcast Asks, is the World Really Enchanted, or Disenchanted? (MindMatters) V4V/TALENT ANTARCTICA 1:59:06 V / 1:53:01 P How a plane mechanic named Bennie Roth became first Jew to set foot on Antarctica (Forward) SPEAKPIPE/TALENT/TIME 2:06:54 V / 2:00:49 P OUTRO 2:17:09 V / 2:11:04 P END 2:28:00 V / 2:21:55 P

Flyover Conservatives
Organoids | The Matrix Was NOT Fiction | Flyover Report

Flyover Conservatives

Play Episode Listen Later Jun 26, 2024 24:36


Send us a Text Message.TO WATCH ALL FLYOVER CONTENT: www.flyover.liveTO WATCH ALL FLYOVER CONTENT: www.flyover.liveTo Schedule A Time To Talk To Dr. Dr. Kirk Elliott Go To To Schedule A Time To Talk To Dr. Dr. Kirk Elliott Go To ▶ https://flyovergold.com▶ https://flyovergold.comOr Call 720-605-3900 Or Call 720-605-3900 Check out our other economic updates here ▶  https://subsplash.com/flyoverconservatives/media/ms/+93kmffvCheck out our other economic updates here ▶  https://subsplash.com/flyoverconservatives/media/ms/+93kmffv--------------------------------------------------------------------------------------

The Scientist Speaks
Organoids in Space: The Next Frontier

The Scientist Speaks

Play Episode Listen Later Jun 26, 2024 16:33


Building miniature brains may sound like a page out of a science fiction novel, but fact is indeed stranger than fiction. Researchers around the world grow brain organoids—3D miniature brains—to better understand brain development, aging, injury, and other disorders, as well as to test new treatment strategies. Some scientists take brain building to the next level by launching their brain organoids into outer space. In this episode, Iris Kulbatski from The Scientist spoke with Alysson Muotri, a University of California, San Diego professor and Stem Cell Program director to learn more about how microgravity affects the cellular and molecular biology of brain organoids and how these discoveries can improve human health.  The Scientist Speaks is a podcast produced by The Scientist's Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research. This month's episode is sponsored by ACROBiosystems and Molecular Devices.

Forum
Organoids Roundtable: Lancaster and Pasca

Forum

Play Episode Listen Later Jun 26, 2024 39:55


In this episode of Forum, Chief Editor Barbara Cheifet speaks with Madeline Lancaster and Sergiu Pasca about organoids – cell cultures derived from stem cells and crafted to replicate a particular organ or certain cell types that make up an organ. These two experts in the field discuss neural organoids specifically, and how they are being used to study both basic biology of the brain and their future impacts on disease research. Hosted on Acast. See acast.com/privacy for more information.

Unapologetically Outspoken
A CHATBOT RUNS FOR MAYOR, LAB-GROWN BRAINS, KILLER ROBOT DOGS, AND A HUMANOID PANEL DOMINATES A GLOBAL PRESS CONFERENCE

Unapologetically Outspoken

Play Episode Listen Later Jun 24, 2024 47:22


On today's podcast, Stephanie and Tara talk about some recent stories in the increasingly disturbing world of AI. Your hosts talk about OpenAI's recent partnership with Apple, an AI chatbot running for mayor of Cheyenne in Wyoming, lab-grown brains being used to power AI, more research studies showing AI's deception capabilities, some scary AI developments in China's military strategies, Ukraine creating the world's first drone warfare military branch, the global race to create killer robot dogs, and the recent UN Good Global Summit in Geneva with the world's first press conference with a panel of AI humanoid robots.  Read the blog and connect with Tara and Stephanie on TikTok, YouTube, Rumble, Facebook, and IG. https://msha.ke/unapologeticallyoutspoken/ Want to support the podcast and join the conversation? Head over to our Etsy store and pick up a cool UO Podcast sticker. https://www.etsy.com/shop/UOPatriotChicks  

From the Spectrum: Finding Superpowers with Autism
Dr. Catherine Lord: The Evolution of Autism Assessment, Challenges with Understanding the Spectrum of Autism, and Barriers in the Medical and Education Systems for Autism

From the Spectrum: Finding Superpowers with Autism

Play Episode Listen Later Jun 17, 2024 51:39


In this episode, we discuss Autism with Dr. Catherine Lord. Dr. Lord is a Distinguished Professor of Psychiatry and Education at UCLA and one of the foremost researchers in Autism. Dr. Lord provides tremendous insights into her roles in Autism and Autism Assessment.Dr. Lord discusses her journey into Autism, the evolution of the Assessment including the ADOS growing from her basement and being overran by demand to the Gold Standard, the Challenges with understanding the Spectrum, updates on the Lancet Commission and Profound Autism, and Barriers in the Medical and Educational Systems.Dr. Catherine Lord:https://www.semel.ucla.edu/autism/team/catherine-lord-phdhttps://childmind.org/bio/catherine-lord-phd/https://labs.dgsom.ucla.edu/lord/pages/our_teamThe Lancet Commission https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01541-5/abstractThe Lancet https://pubmed.ncbi.nlm.nih.gov/30078460/Nature Reviews Disease Primers https://pubmed.ncbi.nlm.nih.gov/31949163/Autism and Education https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000656055638https://music.amazon.com/podcasts/d948fecc-8cfa-4203-8493-a12d2c9c92ed/episodes/bf7ce843-0dd2-4fe8-b800-82ea9cace96d/from-the-spectrum-finding-superpowers-with-autism-autism-and-educationThe mention of a recent article on Predicting Profound Autism and Cell Biology and me shying away from saying "Organoids" in real-time https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11127428/(0:00) Intro(3:22) Dr. Lord's journey into Autism and Recognizing a Spectrum(11:25) The Evolution of Autism Assessment and Discussion on the ADI and ADOS- from making the ADOS in her Basement and being Overran by Demand to the Gold Standard; Revisions of Assessment Instruments(16:36) Gaps in the Autism Assessment(23:15) The Challenges with Understanding the Spectrum of Autism(29:32) Updates on the Lancet Commission and Profound Autism(35:19) Barriers with Autism and the Medical Field(39:29) Barriers with Autism and Education- Four Strikes against the Autistic Phenotype: Sensory-Processing, Speech and Language, Social Communication/Interaction, and Subject Switching (understand B3: Fixated Interests)(44:25) The Future of Autism and Helping Autistics Across the Life Span(51:03) Reviews/Ratings and Contact Infoemail: info.fromthespectrum@gmail.com

The James Cancer-Free World Podcast
Episode 162: New Research & Treatment for Adrenal Cancers, Drs. Dedhia and Miller

The James Cancer-Free World Podcast

Play Episode Listen Later Apr 16, 2024 25:31


Because adrenal cancer is so rare, very few cancer hospitals have specialists equipped to treat patients and perform research and offer clinical trials for this type of cancer. “Very few physicians ever see a case in their lifetime and so there are a lot of physicians out there who don't really understand the disease process,” said Barbra Miller, MD, the co-director of the James Multidisciplinary Adrenal Clinic. “I want to make sure patients get good, consistent and comprehensive and safe care and as a surgeon I want to make sure every patient gets the best surgery.” In this episode, Miller and Priya Dedhia, MD, PhD, a James expert in adrenal surgery and research, discussed this rare form of cancer and the wide range of screening and treatment options at the James, and their cutting-edge research. There are currently no screening procedures, such as mammograms for breast cancer or colonoscopies for colon cancer. This means adrenal cancer is often first diagnosed in the later stages when it has metastasized and spread. “We don't know there's a tumor until it's quite large or has gone somewhere else, and another way we know is if [the cancerous adrenal gland] overproduces hormones,” Miller said. Some of the research at the James is focused on understanding how benign tumors in the adrenals can become cancerous. “We know colon cancer starts as a benign polyp,” Miller said. “We never thought this was true with adrenal cancer but now we're at the stage where we think we can prove this is true.” Surgery is the primary modality for treating adrenal cancer, often followed by chemotherapy or, in recent years, immunotherapy. “We're working to create new models for adrenal cancer treatment,” Dedhia said, adding that in her lab she has created “organoids” that “are like patient avatars and help us better understand and treat the cancer.” Organoids are masses of cells grown in the lab and can be used to test the effectiveness of new drug treatments, such as immunotherapy, prior to clinical trials in patients. “We've found two new pathways that kill these organoid cells and the next step we're hoping for is a clinical trial,” Dedhia said. “We believe we've found a way to improve the immune response [of new immunotherapy drugs] and we're very excited.”

Frosty, Heidi and Frank Podcast
Heidi and Frank - 03/05/24

Frosty, Heidi and Frank Podcast

Play Episode Listen Later Mar 5, 2024


Topics discussed on today's show: Sierra Nevada Blizzard, Oregon Drugs, Sports News, Deaths, Claude and Organoids, Birthdays, History Quiz, Boeing Being Sued, Traveling, TV Show Catch Phrases, The Trendmill, Cool People, Proposal Rejection, Less Sex Today, and Apologies.

Ask Doctor Dawn
Compounded weight loss drugs, cloned monkeys for research, retinal organoids and other diverse topics

Ask Doctor Dawn

Play Episode Listen Later Jan 19, 2024 53:25


KSQD 1-17-2024: Compounding the Semaglutide weight-loss drugs reduces its cost If you have had COVID, you can now return to work after 24 hrs if you are fever-free; Exposure to the smell of tears from women appears to reduce aggression in men! Psialic helps stop the spread of flu; The problems of using cloned rhesus monkeys for drug development research; Does Ibuprofen help getting to sleep? Urinary incontinence was fixed by good physical therapy; Retinal organoids explain how humans see so many colors; Declines in blood levels of lead are associated with long term cardiovascular health improvements; The various sources of toxic polycyclic aromatic hydrocarbons

Science Friday
Brain ‘Organoids': Lab-Grown Cell Clusters Model Brain Functions

Science Friday

Play Episode Listen Later Jan 17, 2024 13:55 Very Popular


Brain organoids are grown in a lab using stem cells, and can mimic the functions of different regions of the brain like the cortex, retina, and cerebellum. Though it may sound a bit like science fiction, this technology is increasingly being used to better understand brain disorders and eventually develop better treatments.Ira talks with neuroscientist Dr. Giorgia Quadrato, assistant professor of stem cell biology and regenerative medicine at the University of Southern California, about the state of brain organoid research and her model that mimics the cerebellum.Transcripts for each segment will be available after the show airs on sciencefriday.com. To stay updated on all things science, sign up for Science Friday's newsletters.