POPULARITY
6 episodes with Wistar
3 episodes with Wistar
2 episodes with Wistar
2 episodes with Wistar
2 episodes with Wistar
2 episodes with Wistar
2 episodes with Wistar
2 episodes with Wistar
5 episodes with Wistar
We are building up rodent society in Rats of Wistar, and boy did we create a real Ratopia. How does one build up rat society? What cool adventures do rats go on? How do they manage to make super computers and jetpacks? Ever wonder about "dead game mechanics"? We discuss several from an article on BGG which you can check out below.https://boardgamegeek.com/geek...
Welcome adventurers! Today its Just Patrick and King Scott, with a couple of visitors throughout! King tells us all about his time at GAMA, then its on to game talk. Namely A Gest of Robinhood, Cover your Assets, and Floristry. The 8-bit breakdown goes to a tense two player duel game called Super Snipers! We look back on Rats of Wistar, then do a little game-trotting with Navigator Lana! Finally, don't miss out on a chance to win a copy of today's review game... just click here and join the discord, then click the contest topic! www.levelupgamepodcast.com X Facebook Instagram
Brendan looks back at 2023 and reflects on which games are his favorite and which games deserve special recognition. Join us, won't you?Exempted from Consideration49. Evacuation (2023)Top 5 Games of 2023Nucleum (2023)Voidfall (2023)Septima (2023)Daybreak (2023)Forest Shuffle (2023)Superlative Games of 2023Best Legacy Game: Sagrada Artisans (2023)Coolest Gimmick: Faraway (2023)Most silly: DroPolter (2023)Funniest: Freelancers: A Crossroads Game (2023)Most meditative: Tipperary (2023)Best game no one wants to play with me: Fiction (2023)Awesome Components: Globetrotting (2023)2023 games I have played but did not grant awardsEarth (2023)Star Wars: The Deckbuilding Game (2023)Sky Team (2023)Age of Innovation (2023)Cosmoctopus (2023)Distilled (2023)Apiary (2023)Forbidden Jungle (2023)The A.R.T. Project (2023)Thunder Road: Vendetta (2023)After Us (2023)Nimalia (2023)Expeditions (2023)Rats of Wistar (2023)Point City (2023)That's Not a Hat (2023)Everdell Farshore (2023)Amun-Re: 20th Anniversary Edition (2023)Chicken! (2023)Bark Avenue (2023)Dungeons & Dragons: Bedlam in Neverwinter (2023)Mother of Frankenstein (2023)Smug Owls (2023)TIME Stories Revolution: Cavendish (2023)Leaf (2023)Perspectives (2023)2023 games that I want to play but haven't.Earthborne Rangers (2023)The Fox Experiment (2023)Sail (2023)My Island (2023)First in Flight (2023)Wild Tiled West (2023)City of the Great Machine (2023)Hollywood 1947 (2023)Hegemony: Lead Your Class to Victory (2023)Darwin's Journey (2023)The White Castle (2023)Ticket to Ride Legacy: Legends of the West (2023)The Vale of Eternity (2023)Knarr (2023)Stationfall (2023)Kutná Hora: The City of Silver (2023)Unmatched Adventures: Tales to Amaze (2023)What are your favorite 2023 games? Share your thinking over on Boardgamegeek in guild #3269.
Brendan looks back at 2023 and reflects on which games are his favorite and which games deserve special recognition. Join us, won't you?Exempted from Consideration49. Evacuation (2023)Top 5 Games of 2023Nucleum (2023)Voidfall (2023)Septima (2023)Daybreak (2023)Forest Shuffle (2023)Superlative Games of 2023Best Legacy Game: Sagrada Artisans (2023)Coolest Gimmick: Faraway (2023)Most silly: DroPolter (2023)Funniest: Freelancers: A Crossroads Game (2023)Most meditative: Tipperary (2023)Best game no one wants to play with me: Fiction (2023)Awesome Components: Globetrotting (2023)2023 games I have played but did not grant awardsEarth (2023)Star Wars: The Deckbuilding Game (2023)Sky Team (2023)Age of Innovation (2023)Cosmoctopus (2023)Distilled (2023)Apiary (2023)Forbidden Jungle (2023)The A.R.T. Project (2023)Thunder Road: Vendetta (2023)After Us (2023)Nimalia (2023)Expeditions (2023)Rats of Wistar (2023)Point City (2023)That's Not a Hat (2023)Everdell Farshore (2023)Amun-Re: 20th Anniversary Edition (2023)Chicken! (2023)Bark Avenue (2023)Dungeons & Dragons: Bedlam in Neverwinter (2023)Mother of Frankenstein (2023)Smug Owls (2023)TIME Stories Revolution: Cavendish (2023)Leaf (2023)Perspectives (2023)2023 games that I want to play but haven't.Earthborne Rangers (2023)The Fox Experiment (2023)Sail (2023)My Island (2023)First in Flight (2023)Wild Tiled West (2023)City of the Great Machine (2023)Hollywood 1947 (2023)Hegemony: Lead Your Class to Victory (2023)Darwin's Journey (2023)The White Castle (2023)Ticket to Ride Legacy: Legends of the West (2023)The Vale of Eternity (2023)Knarr (2023)Stationfall (2023)Kutná Hora: The City of Silver (2023)Unmatched Adventures: Tales to Amaze (2023)What are your favorite 2023 games? Share your thinking over on Boardgamegeek in guild #3269.
The Integrative Cancer Solutions podcast, hosted by Dr. Karlfeldt, introduces Chris Burres, the chief scientist at My Vital C. They discuss a groundbreaking molecule called ESS 60, discovered in 1985 by scientists at Rice University. This molecule, shaped like a soccer ball with 60 carbon atoms, initially found use in industrial applications before its potential health benefits were uncovered. A toxicity study on Wistar rats revealed that ESS 60 extended their lifespan by 90%, shifting focus towards its health applications. Users of the My Vital C product containing ESS 60 report improved mental focus, increased energy, and better sleep. The molecule has shown promise in preventing tumor growth in rats and potentially enhancing the efficacy of anticancer agents. However, it's important to note that while ESS 60 is not claimed to cure cancer, it's suggested as a possible cancer preventative. The manufacturing process for ESS 60 is complex and expensive, involving the vaporization of graphite rods in a vacuum chamber, which emphasizes the importance of high-quality production. The recommended dosage is one teaspoon daily, preferably in the morning, with olive oil serving as a carrier to improve bioavailability. Recent studies have shown that the product can reduce high-sensitivity C-reactive protein (hsCRP) levels in four to six weeks, which is an important indicator of overall health and cancer risk. The company behind My Vital C is committed to ongoing research and transparency, offering different oil options (olive, avocado, and MCT) for consumers and providing additional information through their book, "Live Longer and Better."ESS 60, a molecule discovered in 1985 and shaped like a soccer ball with 60 carbon atoms, has shown potential health benefits including extending the lifespan of rats by 90% in toxicity studies.Users of My Vital C, which contains ESS 60, report improved mental focus, increased energy, and better sleep quality.While not claimed to cure cancer, ESS 60 has demonstrated tumor growth prevention in rats and may enhance the efficacy of anticancer agents.The recommended dosage is one teaspoon daily, preferably in the morning, with olive oil as a carrier to improve bioavailability.Recent studies indicate that the product can reduce high-sensitivity C-reactive protein (hsCRP) levels in 4-6 weeks, which is an important indicator of overall health and cancer risk.----The Cancer Revolution: https://www.amazon.com/s?k=the+cancer+revolution+by+dr.+leigh+connealy+book&crid=2GS09LV93ONK5&sprefix=The+Cancer+Revolution%2Caps%2C199&ref=nb_sb_ss_ts-doa-p_2_21Be Perfectly Healthy: https://www.amazon.com/s?k=be+perfectly+healthy+dr+connealy&crid=30H1M792AF1Q6&sprefix=be+perfectly+healthy%2Caps%2C142&ref=nb_sb_ss_ts-doa-p_1_20----Website: https://www.drrobertwhitfield.com/Youtube: https://www.youtube.com/@breastimplantillnessexpertApple Podcast: https://podcasts.apple.com/us/podcast/explant-breast-surgery-recovery/id1678143554Grab my book A Better Way to Treat Cancer: A Comprehensive Guide to Understanding, Preventing and Most Effectively Treating Our Biggest Health Threat - https://www.amazon.com/dp/B0CM1KKD9X?ref_=pe_3052080_397514860 Unleashing 10X Power: A Revolutionary Approach to Conquering Cancerhttps://store.thekarlfeldtcenter.com/products/unleashing-10x-power-Price: $24.99-100% Off Discount Code: CANCERPODCAST1Healing Within: Unraveling the Emotional Roots of Cancerhttps://store.thekarlfeldtcenter.com/products/healing-within-Price: $24.99-100% Off Discount Code: CANCERPODCAST2----Integrative Cancer Solutions was created to instill hope and empowerment. Other people have been where you are right now and have already done the research for you. Listen to their stories and journeys and apply what they learned to achieve similar outcomes as they have, cancer remission and an even more fullness of life than before the diagnosis. Guests will discuss what therapies, supplements, and practitioners they relied on to beat cancer. Once diagnosed, time is of the essence. This podcast will dramatically reduce your learning curve as you search for your own solution to cancer. To learn more about the cutting-edge integrative cancer therapies Dr. Karlfeldt offer at his center, please visit www.TheKarlfeldtCenter.com
Why not buy a board game from our sponsors Kienda: kienda.co.uk/polyhedroncollider Warning: This podcast contains strong language and adult content In this episode of the Polyhedron Collider Cast, the team dives into the latest board game news, reviews, and some seriously unexpected topics, like geese! Tune in as we discuss playing the Warhammer 40k Space Marine VR experience, review a cheese board of games, and design the Dunelm board game. We take a deep dive into the strategic and resource-management game Inventors of the South Tigris, asking is it a worthy end to the South Tigris trilogy. We then take a look at Fromage a quirky worker placement game about making cheese. Is it as rich in flavor as it sounds or does it stink like a ripe Stilton? We round off the cheese theme with the Rats of Wistar, is it a bad game, or are Sid and Rory just bad gamers? Games Mentioned 00:00:34 Untitled Goose Game 00:04:02 Space Marine VR Defenders of Avarax 00:11:07 Inventors of the South Tigris 00:32:36 Fromage 00:46:15 Rats of Wistar 01:07:30 Dunelm the board game ⭐Show Sponsor: Kienda When you sign up to an account with Kienda use this link to bag yourself a wee discount and help support the show. Let's face it, you were going to buy a board game anyway
In Episode 331 we give our hot take review on Rats of Wistar covering the mechanisms, the production, and our overall feelings of the game. We share poll results on buying games with the intent to sell them at a higher price and then discuss some games that have been on our table including Frozen Frontiers, Rebel Princess, and Dune: Imperium. Timestamps: 00:00 Introduction 00:25 Poll: Have you ever bought a game with the intention of flipping it, either for selling or trading it? 13:05 Rats of Wistar Description 15:12 Gameplay and Mechanisms 31:30 Production and Theme 38:50 Final Thoughts 42:54 Frozen Frontier 45:25 Rebel Princess 50:32 Dune: Imperium If you enjoy the show, please consider supporting us at https://www.patreon.com/boardgamehottakes Follow us on BlueSky: https://bsky.app/profile/boardgamehottakes.bsky.social Join our Facebook Community: https://www.facebook.com/groups/boardgamehottakes Join our Board Game Arena Community: https://boardgamearena.com/group?id=11417205 Join our Discord server at: https://discord.gg/vMtAYQWURd
Board Boys are back to get all the cheese in Fromage, a game about making all the cheese by Ben Rosset and Michael O'Malley. 0:00 Intro, E.V.A. - Jean Jacques Perrey 8:00 Pirates of Maracaibo: Commanders 14:00 Welcome to the Moon 22:45 Planta Nubo 29:30 Hamster Roll 31:15 Harmonies 35:00 Fromage: Overview 40:00 MMM Cheese - Freddy 4X 41:00 Fromage: Review 1:08:00 Fromage: Verdict 1:14:00 Board Boys Bump: Rats of Wistar 1:20:00 Thank You, Patrons 1:20:30 This Will Be Our Year - The Zombies
This week Jules, Joe and Lauren wax lyrical about the games hitting their table recently, with some very sizzling and some lukewarm receptions. Jules has been practicing his dexterity skills in Nekojima - a game about installing electricity poles without crossing or touching their cables. Joe pieces together all the information to share his perspective on Perspectives - a game about solving mysteries while sharing limited information with friends. To round us off, Lauren and Jules discuss their mixed feelings with the very beautiful looking Rats of Wistar. They also share the community responses from last week's Question of the Pod, anticipate what games they could play in this week's question, and get fired up for the coming week! New Question of the Pod: What game are you dying to get off your shelf of shame, and how will you get it played? Timestamps: Nekojima [0:26:27] Perspectives [0:32:58] Rats of Wistar [0:42:07] Question of the Pod: [0:57:24] Fired Up: [1:09:55] Check out our Eventbrite page for all of our upcoming Game Days: https://www.eventbrite.com.au/o/board-game-bbq-32833304483 Has this episode left you with a thirst for more? Here are all of the games that we discussed: Lord of the Rings: Duel for Middle-earth - https://boardgamegeek.com/boardgame/421006/the-lord-of-the-rings-duel-for-middle-earth Arcs - https://boardgamegeek.com/boardgame/359871/arcs The String Railway Collection - https://boardgamegeek.com/boardgame/391720/the-string-railway-collection Kiri-ai: The Duel - https://boardgamegeek.com/boardgame/387769/kiri-ai-the-duel Exceed Fighting System - https://boardgamegeek.com/boardgame/224483/exceed-fighting-system Pixies - https://boardgamegeek.com/boardgame/411875/pixies Yokai Septet - https://boardgamegeek.com/boardgame/251433/yokai-septet Speakeasy - https://boardgamegeek.com/boardgame/375459/speakeasy Nekojima - https://boardgamegeek.com/boardgame/359029/nekojima Perspectives - https://boardgamegeek.com/boardgame/400995/perspectives Rats of Wistar - https://boardgamegeek.com/boardgame/387780/rats-of-wistar SPONSORS Our podcast is proudly sponsored by Advent Games. Advent Games (http://www.adventgames.com.au/) are an Australian online board game store based in Sydney, NSW. Their core values are integrity, customer satisfaction, and providing a wide range of products including those hard-to-find board games. More Than Meeples is an Australian retail and online game store based in Brisbane, QLD. They have been strong supporters of, not only our Brisbane Game Days, but the broader Brisbane community. https://morethanmeeples.com.au/ PATREON Hey there, BBQ fans! Guess what? We've got a Patreon! By joining, you'll unlock exclusive content, gain access to a members-only section of our Discord where you can help shape the show, and so much more. Plus, your support will help us grow and bring some awesome new projects to life in 2024. At the Board Game BBQ Podcast, we're passionate about what we do and promise to keep the fun and shenanigans rolling. We're so grateful for your support! Joining our Patreon is totally optional, and we ask that you don't contribute if it'll cause financial stress. But if you'd like to chip in from just USD$5 a month, click the link to check out our Patreon page. Thanks a million for being amazing! We're committed to creating a welcoming and inclusive community, and you all make it special. See you at the BBQ!! https://www.patreon.com/BoardGameBBQ SOCIALS Support the podcast and join the community! https://linktr.ee/BoardGameBBQ
Brendan talks about three games he tried for the first time recently, and one he dusted off. Join us, won't you?Rats of Wistar (2023)Bullet♥︎ (2021)The Hunger (2021)Race for the Galaxy (2007) (revisited)What games have you tried recently? Join us over on boardgamegeek in guild #3269 to share your game plays!
Brendan talks about three games he tried for the first time recently, and one he dusted off. Join us, won't you?Rats of Wistar (2023)Bullet♥︎ (2021)The Hunger (2021)Race for the Galaxy (2007) (revisited)What games have you tried recently? Join us over on boardgamegeek in guild #3269 to share your game plays!
HEALTH NEWS · Eat This to Think Better for the Next Six Hours -- and Beyond · Americans over 40 could live extra 5 years if they were all as active as top 25% of population, modeling study suggests · Exposure to marijuana in the womb may increase risk of addiction to opioids later in life, study finds · Maternal stress linked to increased early onset epilepsy in children · Gut microbiome found to play key role in chronic disease progression · Chewing xylitol gum linked to decrease in preterm birth Russian scientists make alarming 5G discovery Cellphone radiation has led to changes in the brain tissue of lab rats Controlled exposure to the 5G radiation spectrum has resulted in changes to the brain tissue of laboratory rats, according to a team of scientists from Tomsk State University (TSU) in Russia. Ever since the introduction of 5G cellphone infrastructure, there have been concerns about its potential health effects. The International Agency for Research on Cancer has classified the 5G radio frequency electromagnetic field (RF-EMF) as a “possible” human carcinogen, but no conclusive research has emerged either way. “We decided to find out what the effect of non-ionizing radiation is on rodents of different ages,” Natalia Krivova, lead researcher at the TSU's Biology and Biophysics Research Institute, said in a statement this week. TSU scientists experimented on male Wistar rats, preferred by scientists for having similar reactions to external stimuli as humans. They tested three different age groups: 5-6 week old rats (corresponding to human adolescents), 10-11 week old (human adults age 40 and up) and rats aged 17-18 weeks (humans 65 and older). All were exposed to RF-EMF frequencies for five weeks, which is equivalent to about four years of human lifespan. The study showed no outward changes between the rats exposed to the radiation and the control group. “However, a more detailed study of the rats' brain tissue after exposure to the 5G antenna revealed a significant change in the ratio of antioxidants and oxidants,” Krivova said. It is still unclear whether the changes will lead to positive or negative changes in the rats' cognitive abilities, or whether their bodies will somehow compensate for the disruption, she added, calling for further research into the subject. The Tomsk study represents the first time scientists have been able to measure the radiation absorption rate on caged rodents, according to the university. The TSU radiophysics team led by Professor Sergey Shipilov designed the 5G antenna for the experiment, and a team led by postgraduate student Ramdas Mazmanazarov developed a method for measuring the absorption rate. Their work was published earlier this year in the journal Applied Sciences. The study was part of the International Electromagnetic Field Project, initiated by the World Health Organization (WHO) to obtain science-based and objective answers to questions of public concern about the possible health risks from 5G electromagnetic fields. According to Krivova, the next stage of research is intended to study female rats and investigate how 5G radiation might affect their offspring, if funding can be secured.
Brendan talks about three games he played recently for the first time, and one he dusted off. Join us, won't you?Rats of Wistar (2023)The Hunger (2021)El Grande (1995)Revisited Azul: Stained Glass of Sintra (2018)What games have you tried out lately? Share your thoughts over on boardgamegeek in guild #3269.
Brendan talks about three games he played recently for the first time, and one he dusted off. Join us, won't you?Rats of Wistar (2023)The Hunger (2021)El Grande (1995)Revisited Azul: Stained Glass of Sintra (2018)What games have you tried out lately? Share your thoughts over on boardgamegeek in guild #3269.
In this episode of Wistar Science Up Close, Dr. Maureen Murphy gets insights from Wistar postdoctoral student, Dr. Ebony Gary and first year Ph.D. cancer biology student Tyler Yang about life in and outside of the lab. Hear firsthand how they balance a career in biomedical research and their life outside the lab.
In der heutigen Podcast-Episode 307 blicke ich mal wieder auf meine Erfahrungen mit einigen Brettspielen zurück. Darunter sind auch 2 SPIEL '24 Neuheiten. Zudem beschäftige ich mich mit einem möglichen Umzug der Messe SPIEL und gehe ein wenig auf die Pro- und Contra-Argumente, sowie die umfangreichen Meinungen meiner Leser dazu ein.
Aquí tenéis un nuevo episodio de vuestro podcast maderil favorito en el que vamos a analizar en profundidad uno de los últimos éxitos de Cranio Creations. Además, recuperamos la sección de estante lustroso para desahogarnos un poco con ciertos juegos. Ahí os va el menú: (0:06:04) El Juego del Programa: Rats of Wistar (1:19:55) Estante Lustroso: Pinos y Castaños: (1:21:42) Hamlet (1:26:57) Barrio (1:32:02) 3000 Granujas (1:38:23) Imperium (1:47:20) AvGhost (1:53:22) Bruges
"If you had the same mental capacity and physical capacity that you have today, would you then be interested in living longer? It shifts everything." - Chris Burres Chris Burres is the founder and chief scientist at MyVitalC, a company that manufactures a Nobel Prize-winning molecule called ESS60. With a background in research and a passion for helping people live longer and healthier lives, Chris is dedicated to spreading awareness about the benefits of ESS60 and its potential to extend lifespan and improve overall well-being. Episode Summary: In this episode, host Jana Short interviews Chris Burres, the founder and chief scientist at MyVitalC. They discuss the revolutionary molecule ESS60, its role in extending lifespan, and the importance of living longer and healthier lives. Chris shares the fascinating story behind the discovery of ESS60 and its incredible effects on longevity. He also explains the science behind ESS60, its anti-inflammatory properties, and its positive impact on sleep. The conversation highlights the need for a mindset shift when it comes to living longer and the potential for a longer health span. Key Takeaways: ESS60 is a Nobel Prize-winning molecule that has shown a 90% extension of life in Wistar rats in a scientific study. A common misconception is that living longer means living in a debilitated state. The goal is to live longer and healthier, not just exist longer. ESS60 has anti-inflammatory properties and is 125 times more powerful than vitamin C in reducing inflammation. Sleep plays a crucial role in overall health and well-being. ESS60 has been reported to improve sleep quality, leading to better mental, physical, and emotional well-being. The MyVitalC products, particularly the olive oil-based formula, are recommended for those new to ESS60 supplementation. Get in touch with Chris: www.MyVitalC.com/omh (look for a special discount there) https://www.instagram.com/myvitalc/ facebook.com/myvitalc https://www.linkedin.com/in/chrisburres/ Learn more about Live Longer and Better: www.LiveLongerandBetterBook.com Get in touch with Jana and listen to more Podcasts: https://www.janashort.com/ Show Music ‘Hold On' by Amy Gerhartz https://www.amygerhartz.com/music. Get the Best Holistic Life Magazine Subscription! One of the fastest-growing independent magazines centered around holistic living. https://www.bestholisticlife.com/bhl-subscription/ Grab your gift today: https://www.janashort.com/becoming-the-next-influencers-download-offer/ Connect with Jana Short: https://www.janashort.com/contact/
Mit 2 Wochen Verspätung haben wir uns für das GeGeGe im Juni zusammengefunden. Natürlich sind vor allem die Partien unseres 2. Brettspiel Wochenendes in Mannheim ein großer Fokus im Gespielt Teil, sodass ein Highlight hier auf das Nächste folgt. Vielen Spaß beim reinhören. Der Podcast wird Euch präsentiert von Spieletastisch.de - Eurem Shop für Brettspiele. Kapitelmarker 00:04:21 Frage der letzten Folge 00:06:31 Gewinner Spiel des Jahres 00:11:31 GeGeGe 00:12:55 Gebackt Stefan 00:13:13 Mario versucht zu sprechen 00:14:03 Gebackt Mario 00:15:15 Gebackt Björn 00:17:23 Gebackt Basti 00:22:03 Gekauft Björn 00:32:20 Gekauft Stefan & Mario 00:32:46 Gekauft Basti 00:35:36 Gespielt Mario 00:36:05 Heroes of Might & Magic III: The Boardgame 00:47:53 Axon Protocol 00:54:58 Bamboo 01:03:37 Mario Sonstiges 01:04:24 Gespielt Björn 01:05:18 Pax Pamir 01:10:24 Rebel Princess 01:14:32 Blood Bowl Team Manager 01:19:59 Björn Sonstiges 01:21:03 Gespielt Stefan 01:21:33 Xia: Legends of a Drift System 01:26:51 On the Underground 01:28:04 Trick Shot 01:29:55 3 Minute Crazy Café 01:32:23 Stefan Sonstiges 01:35:22 Gespielt Basti 01:35:32 Die Ratten von Wistar 01:41:23 Great Western Trail: Neuseeland 01:47:43 Blood on the Clocktower 01:59:27 Basti Sonstiges 02:05:13 Highlights & Lowlights 02:12:57 Frage der Folge 02:15:22 Aufruf Verstärkung für die BP Squad Den Podcast findet Ihr u.a. auf folgenden Plattformen: iTunes / Spotify / Google Podcasts / Deezer Sowie in jeder Podcast App unter dem folgenden Feed: https://brettspiel-podcast.podcaster.de/brettspiel-podcast.rss Alle wichtigen Links zu uns findet Ihr in unserem Linktree Folge direkt herunterladen
In this episode The Wistar Institute's podcast, we take a deep dive with Dr. Luis Montaner, one of Wistar's longest-serving scientists. Listen today as he discusses his lab's groundbreaking HIV cure research and how he decided to dedicate his life to the cause of searching for an HIV cure.
Welcome to episode 64! It's all about rat themed or rat adjacent games. We discuss a number of rat games, including First Rat, Rattus, and Rats of Wistar. What are your favorite rat themed games? Rat Games: First Rat - 00:04:03 Rattus - 00:15:33 Rats of Wistar - 00:30:20 Messina 1347 - 00:43:42 Quacks of Quedlinburg - 00:53:40 Cockroach Poker - 01:00:29 Join our Discord: https://discord.gg/F4kX3Faxxf Other links : https://linktr.ee/Longestturn Affiliate codes: GameNerdz, Boardlandia (5% discount) Support us on Buy Me a Coffee!
Dear cultists! How are you? Today, English lesson. Lesson 1. The cat is on the table. The pen is blue. The entity is on the multilinear plane of existence. The invocation is nearly completed. Lost limbs will be replaced by merciful obscurity. Dato che ci seguite in tanti, e i numeri delle scorse settimane sono molto belli e incoraggianti, ci siamo sentiti in dovere di fornire alcune note educational a questo podcast. In altre parole, restituire alla comunità un po' di tutto il benessere di cui noi e i denti del Duca godiamo. Da veri filantropi, ci è sembrato giusto iniziare con un piccolo vademecum costituito da frasi di facile e frequente utilizzo per tutti voi che amate il disagio e l'oscurità. Un abbraccio forte.Buon ascolto e come sempre… Ci vediamo dall'altra parte!Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/dunwich-buyers-club--2814177/support.
In our two hundred and twenty-ninth episode, Aaron is joined by Scott. We talk about Rats of Wistar and French Quarter in the BA Banter. We reflect on our review of King's Dilemma. Then we get into Aaron's Top 40 Games of All Time, going from 20 to 11 and Scott's Top 18 Games of All Time. This episode is sponsored by Board Game Bliss and listeners like you on our Patreon
Mel und Manolo haben sich endlich mal persönlich getroffen. Natürlich zum Spielen. Und zwar in Tann. Das ist in Hessen. An der Rhön. Wie es dazu gekommen ist, und was sie alles gespielt haben, davon erzählen sie Euch in dieser Folge, die in völlig authentischem Landhotelzimmer-Stil aufgezeichnet wurde. Alle damit einhergehenden Nebengeräusche und Tonqualitätsschwankungen bitten wir zu entschuldigen. Ablauf der Folge: [00:00:00] Intro und Vorworte [00:04:45] Sag's mir! (aka Time's Up!) [00:05:40] Lisboa [00:08:25] Mage Knight - Das Brettspiel [00:12:10] Splito [00:13:00] Cabanga! [00:13:40] Dice Throne [00:15:40] Die Burgen von Burgund [00:18:25] Sky Team [00:20:30] Botanicus [00:23:25] Die Ratten von Wistar [00:28:25] 'ne Tüte Chips [00:29:45] Captain Flip [00:31:15] Schnitzeljagd [00:32:10] Mischwald [00:33:40] Apiary (aka Astro-Bienen) [00:35:15] Fazit und Verabschiedung Feedback zur Folge bzw. zum Podcast allgemein könnt Ihr uns auf Twitter, Bluesky, im Beeple Discord, im Einzelspiel Discord oder gern auch per Mail an info@solomanolo.de geben. Über ein Abo und/oder eine Bewertung des Podcasts auf iTunes, Spotify & Co. würden wir uns natürlich auch sehr freuen. Vielen Dank fürs Zuhören und bis zum nächsten Mal! Mel & Manolo. Folge direkt herunterladen
Shelley and I compete as ultrasmart rat clans in Rats of Wistar by Simone Luciani and Danilo Sabia from Cranio Creations and Capstone Games then we look once again (prepping to look at expansion maps) at Mini Express by Mark Gerrits from Moaideas Game Design This week's podcast is sponsored by Bezier Games, makers of modern classics like Castles of Mad King Ludwig Suburbia as well as the draw and write sequel Blueprints of Mad King Ludwig and the new trick-taking card games Xylotar and Sandbag
In today's episode, the guys talk about their recent plays at PPCon and review Rats of Wistar. Review starts at 01:29:33 Matthew's Geeklist about attending PPCon https://boardgamegeek.com/geeklist/336878/pp-con-2024-my-first-convention Help support the podcast on Patreon! www.patreon.com/punchboardparadise Join our Discord! discord.gg/4FrZ8S3yCv Check out the Website! punchboardparadise.com Need a new shirt? www.punchboardparadise.threadless.com Music by HookSounds
Reviews of Rats of Wistar, Art Society, Tesseract and so much more. Featured review: Dabba Walla by Queen Games. Board game discussion starts at {00:32:53}. Thank you to our sponsors: Queen Games, and Grand Gamers Guild. The post Episode 266: Dabba Walla appeared first on Blue Peg, Pink Peg Boardgaming Podcast.
HEYOH CABALISTS! The 2024 KICKSTARTER IS LIVE! Stop the podcast now and go support all The Secret Cabal Shows right now. The gang kicks off episode 297 with a little bit about the fundraiser including the Secret Cabal Zine and other rewards. Then the gang gets into the games they've been playing including Terra Mystica, Fortune and Glory, Small World, Golem, Armello, and a feature review of Rats of Wistar from Simone Luciani and Danilo Sabia and published by Capstone Games. Then Tony T gets down and dirty into all the most important news from around the tabletop gaming world for the 297th time (he didn't quit after 12). And finally, the Founders dive into the world of Ameritrash games - the most wild, crazy, and thematic games out there and celebrate what they love about them. Rats of Wistar Review 01:01:27, News with Tony T 01:36:19, Ameritrash Extravaganza 02:44:23. Support the show by pledging to our Kickstarter at https://www.kickstarter.com/projects/secretcabaljamie/the-secret-cabal-gaming-podcast-is-outta-control-in-2024
On this almost chiaroscuro episode of the Shut Up & Sit Down Podcast, Tom and Pip are chatting about games that could not be more different. First up, Rats of Wistar - a crunchy engine-building game with rats and cards and being as efficient as possible within a strict turn limit. That's followed up with Dro Polter and Rafter Five - two Oink games that are some of their silliest yet. Have a great weekend, everybody! Timestamps: 02:10 - Rats of Wistar 25:11 - Dro Polter 36:33 - Rafter Five
Just Patrick and King Scott are joined yet again by Navigator Lana! Today we talk Solstis and Wyrmspan before the 8-bit breakdown of Rats of Wistar! After looking back at Khora, Rise of an Empire, we venture to solo-land to chat about not one, not two, but THREE fantastic games for those of us who play with ourselves... hehe. www.levelupgamepodcast.com Facebook Instagram X BGG Guild
BJ and Jeremy played Barcelona and Rats of Wistar on a recent Twitch Tuesdays in the Gumbo Pot, but before the euro game goodness started, they took a look at two projects on Kickstarter right now for some first impressions: Logic & Lore from Weird Giraffe Games, a two player card game all about deducing the cards already in your tableau; and Cascadia: Rolling Hills from Flatout Games, a multiplayer flip-and-roll-and-write game from Randy Flynn! You can check out the Cascadia Rolling Hills crowdfunding project right here: https://www.kickstarter.com/projects/flatoutgames/cascadia-rolling You can find out more about the Logic & Lore crowdfunding project here: https://www.kickstarter.com/projects/weirdgiraffegames/logic-and-lore Our thanks to the publishers for providing these preview copies. Until next time, laissez les bon temps rouler!
EPISODE 144 of GROWING OLDER LIVING YOUNGER focuses on healthy aging and longevity, to increase health span not just lifespan.Today's featured guest is Christopher Burres, founder and chief scientist at MyVitalC. In Episode 112 of this podcast, I heard from Chris about ESS60, a unique carbon nano molecule, shown in a single 2012 toxicity study to significantly enhance longevity in the exposed group of Wistar rats. Since our interview, Chris has written, together with Jerome Corsi, a book titled Live Longer and Better: Your Journey to Living Longer and Better has Never been more Achievable than Today. I was also interested to hear all about the upcoming online summit which Chris has curated, called Uncovering the Secrets to Longevity: Living Beyond the Norms where you can hear from experts in all aspects of longevity. Episode Timeline: 0:01 introduction to Aging, longevity, and healthy habits 2:21 Aging and longevity biohacking with a focus on ESS60. 6:59 Longevity supplements 13.42 Aging, longevity, and molecular biology. 20:01 Aging, longevity, and biohacking with experts. 26:00 The upcoming Longevity and Living Longer summit 31:45 Aging, stem cells, and longevity. Learn more about Chris Burres and his work: Find the book here: Live Longer and Better: Your Journey to Living Longer and Better has Never been more Achievable Find Uncovering the Secrets to Longevity: Living Beyond the Norms Summit here: Get to know Your Host: Dr. Gillian Lockitch Download your free Guide to Living Younger Longer. Download the Growing Older Living Younger app for smartphone or tablet Schedule a free Discovery Call with Dr. Gill website: https://www.askdrgill.com/ Facebook: https://www.facebook.com/gillian.lockitch/ GOLY Community: https://www.facebook.com/groups/growingolderlivingyounger LinkedIn: https://www.linkedin.com/in/gillianlockitch/ X: https://twitter.com/GilliansReviews
Primer programa de 2024 en el que comenzamos con un vivero repleto de novedades (aunque algún rezagado hay). Ahí os va el menú: El Vivero: (0:03:50) Obsesión (0:25:28) The Glade (0:37:30) Rats of Wistar (0:54:50) Nucleum (1:12:10) Federación (1:20:45) Embarcadero (1:28:18) Coffee Rush (1:38:15) Sea of Strife
Board Boys are back with another Cranio Creation, Rats of Wistar by Danilo Sabia and Simone Luciani, a game about lab rats bustin loose. Is the rat game to end all rat games? Find out more just following the 45 minute intro to this episode (my bad). 0:00 Intro, E.V.A. and The Rose and the Cross - Jean Jacque Perrey 8:15 Scholars of the South Tigris 11:45 Halloween (A Hidden Movement Game) 17:30 The Stifling Dark 22:30 Hollywood 1946 26:45 Rats of Wistar: Overview 29:30 Rat Race - Bob Marley and the Wailers 31:00 Rats of Wistar: Review 1:01:00 Rats of Wistar: Verdict 1:09:00 Board Boys Bump: Woodcraft 1:15:00 Thank You, Patrons 1:15:30 Rat in Mi Kitchen - UB40
Chris Burres is a pioneer in carbon nanomaterials and a co-owner of SES Research Inc., a company delivering groundbreaking solutions in this field since 1991. In our conversation, we explored the remarkable journey of ESS60, a molecule that has been a game-changer in various industries and, more intriguingly, in the field of longevity. Burres detailed the journey of this Nobel Prize-associated molecule from its discovery at Rice University in 1985 to its unexpected role in extending the lifespan of Wistar rats by 90%.One of the most compelling aspects of our discussion was the molecule's journey from industrial applications to a potential longevity elixir. "This molecule is absolutely amazing. In industrial applications, it performs as well or better than the current best material in almost every application," Burres explained. He further delved into the molecule's unique structure, likening it to a soccer ball, where the lines represent bonds between carbon atoms.The conversation took an unexpected turn with the revelation that ESS60, initially assumed to be toxic due to its benzene-like structure, actually contributed to a significant increase in the lifespan of test subjects. This led to Burres and his team pivoting from being "happy go lucky carbon nanomaterial scientists" to entering the supplement industry. This shift was propelled by the remarkable finding that rats administered with ESS60 lived 90% longer than the control group, a result that Burres described as "the single longest longevity experimental result in history."As a business leader and entrepreneur, Burres also shared insights into the challenges and decisions faced when transitioning from manufacturing carbon nanomaterials for industrial use to creating a consumer health supplement. This shift was not without its ethical and legal considerations, as he candidly discussed the journey towards ensuring the product's safety and compliance with FDA regulations.Listeners will find value in Burres' exploration of the mechanisms behind ESS60's effectiveness. He discussed the concepts of oxidative stress and inflammation, and how ESS60 addresses these key factors in aging. The conversation also touched on broader topics in the realm of longevity, including dietary solutions, exercise, and the impact of sleep on overall health.This episode is a treasure trove of insights for anyone interested in the intersection of science, health, and entrepreneurship. It offers a unique perspective on how a scientific discovery can lead to unforeseen opportunities and challenges in the business world.
Welcome to another episode of the podcast this time LIVE from BGGCon 2023. Boardboy Rob is joined by BJ from Boardgame Gumbo and a couple of our friends and lovely patrons Bayou Dave and my roomie Jeremy. Lots of con shenanigans come get your Board Boy Shirts and think about coming to the con next year! Rob gets an opportunity to read BJs Tiletum Bump or Dump thoughts post and boy was it flowery. Until next time we hope you like Boardgames! 2:45 - The Perfect Wave 4:40 - Cathedral of Orleans 8:20 - After Us 12:50 - 3 Ring Circus 15:00 - Newton 17:00 - Challenders Beach Cup 19:00 - Kolaches 20:50 - Rats of Wistar 24:00 - Top Rat Games 25:15 - Sea Salt and Paper 28:30 - Top 3 New to You Games 38:15 - Can't Stop and Lil Wreckers Workshop 47:00 - Last Light Introduction 54:30 - Last Light Main Review 1:21:30 - Last Light Final Thoughts 1:28:05 - Board Boys Bump or Dump - Tiletum 1:37:00 - Patron Thanks and Outro
Adrian, Jeff, and Zach make an important announcement regarding the future of the show. Then Zach runs down all the games he played at BGG.Con. 00:00:44 - Important Announcement 00:12:35 - What have we been playing?: Spirit Island 00:18:32 - Zach BBG.Con Rundown: Day 1: Match of the Century, Sushi Go Dim Sum, Tiger & Dragon, KimJoy's Magic Bakery, Wild Tiled West, Nokosu Dice, Daybreak 00:53:55 - Zach BBG.Con Rundown: Day 2: Empire's End, Last Light, Forbidden Jungle, Wandering Towers, Legendary Encounters: Matrix 01:10:12 - Zach BBG.Con Rundown: Day 3: Nekojima, Crash Octopus, A.R.T. Project, Queen by Midnight, White Castle 01:23:26 - Zach BBG.Con Rundown: Day 4 & 5: Vale of Eternity, Nucleum, Heat, Rats of Wistar, Chicken, Fun Facts, Dogfight, Deep Dive, Herbaceous Pocket MHGG Twitch Discord Patreon Guild
Tom, Chris and Wendy take a look at Rats of Wistar! 0:00 Intro 1:01 Overview 6:05 Final Thoughts
Dan Patriss shares his thoughts on Spiel Essen 2023. Show your thanks to Major Spoilers for this episode by becoming a Major Spoilers Patron at http://patreon.com/MajorSpoilers. It will help ensure Munchkin Land continues far into the future! Join our Discord server and chat with fellow Spoilerites! (https://discord.gg/jWF9BbF) Contact us at podcast@majorspoilers.com NEWS First some stats from W. Eric Martin of BGG News Convention organizer Merz Verlag reports that the show attracted 193,000 visitors from 85 countries, while occupying a total area of 62,500 m² and featuring 935 exhibitors from 56 nations. Planta Nubo The White Castle Sky Team Forest Shuffle Nucleum Imperial Miners VoidFall Civolution FFG Has finally announced release dates for Star Wars Unlimited CCG- (Set 1 Spark of Rebellion) March ‘24 The release will have Booster Packs ($5) A Two-Player Starter (MSRP $35) And a Prerelease Box (MSRP $30) Mindclash games will release Septima into retail Q4 ‘23 ($50) Brotherwise Games will release my current #1 most anticipated game for the year Empire's End Nov ‘23 ($40) CrowD Games will release Portals Nov ‘23 ($45) Floodgate Games big release for ‘23 Sagrada Artisans is now out! ($50) Sagrada legacy Capstone Games has announced an agreement to release Cranio Creations games into US markets. Starting with Rats of Wistar ($70) and Anunnaki: Dawn of the Gods ($100) Lunar Rush, from Dead Alive Games, will release into US retail Oct 23 ($50) Pegasus Spiele will release Djinn, designed by Ben Schwer (Crown of Emara, Hadara) from Hall Games, in November ‘23 ($70) CROWDFUNDING KICKSTARTER Merchants of Magick: Dangerous Business + Draught of Dragons Forage Upcoming KS-- Likely have links to both next show GameToppersLLC-- 2023 campaign featuring young sherlock-- My video Fall Of Lumen-- My Overview Video GAMEFOUND Aberration (Coming Soon below) New Witcher Game Food Chain Magnate
Dan Patriss shares his thoughts on Spiel Essen 2023. Show your thanks to Major Spoilers for this episode by becoming a Major Spoilers Patron at http://patreon.com/MajorSpoilers. It will help ensure Munchkin Land continues far into the future! Join our Discord server and chat with fellow Spoilerites! (https://discord.gg/jWF9BbF) Contact us at podcast@majorspoilers.com NEWS First some stats from W. Eric Martin of BGG News Convention organizer Merz Verlag reports that the show attracted 193,000 visitors from 85 countries, while occupying a total area of 62,500 m² and featuring 935 exhibitors from 56 nations. Planta Nubo The White Castle Sky Team Forest Shuffle Nucleum Imperial Miners VoidFall Civolution FFG Has finally announced release dates for Star Wars Unlimited CCG- (Set 1 Spark of Rebellion) March ‘24 The release will have Booster Packs ($5) A Two-Player Starter (MSRP $35) And a Prerelease Box (MSRP $30) Mindclash games will release Septima into retail Q4 ‘23 ($50) Brotherwise Games will release my current #1 most anticipated game for the year Empire's End Nov ‘23 ($40) CrowD Games will release Portals Nov ‘23 ($45) Floodgate Games big release for ‘23 Sagrada Artisans is now out! ($50) Sagrada legacy Capstone Games has announced an agreement to release Cranio Creations games into US markets. Starting with Rats of Wistar ($70) and Anunnaki: Dawn of the Gods ($100) Lunar Rush, from Dead Alive Games, will release into US retail Oct 23 ($50) Pegasus Spiele will release Djinn, designed by Ben Schwer (Crown of Emara, Hadara) from Hall Games, in November ‘23 ($70) CROWDFUNDING KICKSTARTER Merchants of Magick: Dangerous Business + Draught of Dragons Forage Upcoming KS-- Likely have links to both next show GameToppersLLC-- 2023 campaign featuring young sherlock-- My video Fall Of Lumen-- My Overview Video GAMEFOUND Aberration (Coming Soon below) New Witcher Game Food Chain Magnate
Tom, Julie, and Eric discuss Essen Spiel 2023, including some general information on the layout, food, and happenings at the fair, as well as some of their most anticipated games. Then they close the show with reviews of Ticket To Ride Legacy, Fit to Print, and Deckscape: Tokyo Blackout. 01:27 - Food 04:26 - Layout Changes 17:32 - Booth Schedule (Dice Tower 3W103, Van Ryder Games 2C102) 19:55 - Press Pre-Show 20:49 - Tips 27:07 - Anticipated Games 27:48 - Among Cultists 29:15 - The White Castle 30:45 - Evacuation 31:28 - Lost Ruins of Arnak: The Missing Expedition 31:57 - Nucleum 32:41 - Kutna Hora: The City of Silver 34:09 - From the Moon 34:41 - 3 Ring Circus 35:54 - Karak II 36:58 - World Wonders 38:15 - Arborea 39:27 - Barcelona 40:30 - Shipyard 41:01 - Evil Corp. 41:35 - Sky Team 42:05 - Nekojima 43:06 - Witchcraft 44:02 - 1902 Méliès 45:07 - Zhanguo 46:12 - Rats of Wistar 48:28 - Imperial Miners 49:17 - House of Cats 50:01 - Freaky Frogs from Outaspace 50:27 - The Cathedral of Orleans 51:42 - Ticket to Ride Legacy 57:04 - Fit to Print 1:01:21 - Deckscape: Tokyo Blackout 1:04:19 - Unlock: Short Adventures
Welcome to episode 47! In this episode we talk about some of the games coming out or being previewed at Essen 2023. It is incredible how many games have been announced and we found the ones we are most excited about. We also talk about what we've been playing lately and some crowdfunding games that caught our eye. But before we get to any of the game discussions, we kick it off with a taste test... Pigs & Blankets Vienna Sausages - 00:01:35 Games we've been playing lately: 00:09:20 Lorcana - 00:11:24 Deep Dive - 00:23:44 Knarr - 00:33:08 Undaunted: Stalingrad - 00:43:09 (Check out Episode 43 for our all-things Undaunteds feature episode and David Thompson interview) Expeditions - 00:49:53 Essen Top 5 Preview - 01:05:31: Tyson's #5 Imperial Miners - 01:07:21 Kevin's #5 Shipyard (2nd Edition) - 01:10:42 Tyler's #5 Orleans: The Plague - 01:14:06 #4 Sea Dragons - 01:19:55 #4 ZhanGuo: The First Empire - 01:23:21 #4 How Dare You? - 01:26:48 #3 Anunnaki: Dawn of the Gods - 01:31:44 #3 Evenfall - 01:36:45 #3 Tricky Badger - 01:41:03 #2 Rats of Wistar - 01:46:37 #2 Cascadia: Landmarks - 01:50:20 #2 FLOE - 01:53:26 #1 Books of Time - 01:56:57 #1 Evacuation - 02:02:23 #1 Doggerland - 02:05:47 What we're excited about: Final Girl S3 - 02:12:59 (KRAMPUS!!!) Battle Card, Millennia - 02:16:47 Beast: Shattered Isles - 02:17:50 Vagrantsong: Encore & Off The Rails - 02:19:44 Fromage, Cascadero & Cascadito, Creature Caravan, Dragon Eclipse, Sirens/Defrag/16 Candies - 02:20:30 Outtakes - 2:26:44 Join our Discord: https://discord.gg/F4kX3Faxxf Other links, please subscribe: https://linktr.ee/Longestturn Support us on Buy Me a Coffee!
A teenager was shot and killed at a Henrico apartment complex, according to Henrico Police. Police were called to the Cardinal Forest apartment complex in the 7700 block of Northbourne Court, near Shrader and Wistar roads, at about 8 p.m. Wednesday. There officers found an 18-year-old man with a gunshot wound who was pronounced dead at the scene. He was later identified as Teshawn Damon Archer of Henrico County. Click here to continue reading on WTVR.com, a Henrico Citizen partner organization.Article LinkSupport the show
A new research paper was published in Aging (Aging-US) Volume 15, Issue 11, entitled, “Senescence and senotherapies in biliary atresia and biliary cirrhosis.” Premature senescence occurs in adult hepatobiliary diseases and worsens the prognosis through deleterious liver remodeling and hepatic dysfunction. Senescence might also arise in biliary atresia (BA), the first cause of pediatric liver transplantation. Alternatives to transplantation are needed. In this new study, researchers Giulia Jannone, Eliano Bonaccorsi Riani, Catherine de Magnée, Roberto Tambucci, Jonathan Evraerts, Joachim Ravau, Pamela Baldin, Caroline Bouzin, Axelle Loriot, Laurent Gatto, Anabelle Decottignies, Mustapha Najimi, and Etienne Marc Sokal from the Université catholique de Louvain in Brussels, Belgium, aimed to investigate premature senescence in BA and to assess senotherapies in a preclinical model of biliary cirrhosis. “As there is a need for new therapies to avoid or delay liver transplantation in pediatric biliary cirrhosis, the aim of our work was to investigate premature senescence in BA through a multi-technical approach and to assess senotherapies in a preclinical model of biliary cirrhosis.” BA liver tissues were prospectively obtained at hepatoportoenterostomy (n=5) and liver transplantation (n=30) and compared to controls (n=10). Senescence was investigated through spatial whole transcriptome analysis, SA-β-gal activity, p16 and p21 expression, γ-H2AX and senescence-associated secretory phenotype (SASP). Human allogenic liver-derived progenitor cells (HALPC) or dasatinib and quercetin (D+Q) were administered to two-month-old Wistar rats after bile duct ligation (BDL). Advanced premature senescence was evidenced in BA livers from early stage and continued to progress until liver transplantation. Senescence and SASP were predominant in cholangiocytes, but also present in surrounding hepatocytes. HALPC but not D+Q reduced the early marker of senescence p21 in BDL rats and improved biliary injury (serum γGT and Sox9 expression) and hepatocytes mass loss (Hnf4a). “BA livers displayed advanced cellular senescence at diagnosis that continued to progress until liver transplantation. HALPC reduced early senescence and improved liver disease in a preclinical model of BA, providing encouraging preliminary results regarding the use of senotherapies in pediatric biliary cirrhosis.” DOI - https://doi.org/10.18632/aging.204700 Corresponding author - Giulia Jannone - giulia.jannone@uclouvain.be Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.204700 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, senescence, senotherapy, liver, biliary cirrhosis, biliary atresia About Aging-US Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at https://www.Aging-US.com and connect with us: SoundCloud - https://soundcloud.com/Aging-Us Facebook - https://www.facebook.com/AgingUS/ Twitter - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM
On today's ID the Future, host Andrew McDiarmid rings up Science After Babel author David Berlinski in Paris to discuss the philosopher's latest book. Berlinski is at his cultivated best as the two discuss everything from the biblical Tower of Babel as a metaphor for modern materialistic science, to his friendship with the brilliant and colorful French intellectual Marcel Schützenberger, a world-class mathematician who was self-taught and, as we learn here, came within a hair's breadth of being swept up in the Chinese Revolution. Berlinski also reflects on the seminal 1966 WISTAR symposium, which laid out some mathematical challenges to Darwinism, challenges that Berlinski says remain unanswered to this day. At the same time, Berlinski gives the devil—here Darwinism—its due. Tune in for this and more, and order your copy of Berlinski's Science After Babel here. Source
This is Dice Tower Now for the week of June 6, 2023. This week, restoration arms themselves from my childhood, challengers challenge one more time, distillation gets luthier and luthier, and the gloom is back baby. TOP STORIES (1:55) Gloomhaven second edition announced Zev Shlasinger leaves WizKids Games Steve Jackson Games sales up from past 2 years First info on Restoration Games' Crossbows and Catapults More Ticket to Ride Legacy news Challengers 2 coming from 1 More Time Games and Z-Man Luthier from Paverson Games Djinn from H@ll Games and Benjamin Schwer coming Spiel 2023 Hamlet: By the Lake expansion coming to crowdfunding in July Rats of Wistar by Simone Luciani and Danilo Sabia, published by Cranio Creations Demon Loop, first video game by designer Alexander Pfister CROWDFUNDING (14:35) Age of Steam Deluxe Expansion Set IV Uncharted Stars El Burro: A La Granja Game Carson City Big Box Ruse: Instincts of the Den Into the Godsgrave SPONSOR UPDATE (24:50) Hosting a Lucky Duck Game Night THE HOTNESS (26:30) Frosthaven Gloomhaven Dune: Imperium Darwin's Journey The Witcher: Old World Ark Nova Stranger Things: Upside Down Earth Aeon Trespass: Odyssey Heat: Pedal to the Metal Ticket to Ride Legacy: Legends of the West Gloomhaven: Second Edition CONNECT: Follow our Twitter newsfeed: twitter.com/dicetowernow Dig in with Corey at DiceTowerDish.com. Have a look-see at Barry's wares at BrightBearLaser.com.
Omega-3 fatty acid supplementation could help with cognitive depression Duke University, August 27 2022. An article appearing in the Journal of the American College of Cardiology: Heart Failure reported the outcome of a pilot study that found an association between supplementation with the omega-3 fatty acids EPA and DHA and reduced cognitive depression in heart failure patients. Cognitive depression is characterized by subjective symptoms such as pessimism and sadness, while somatic depression includes physical manifestations that include fatigue and sleep disturbances. The study included 108 patients with a major depressive disorder, chronic heart failure and low blood levels of omega-3 fatty acids. Participants received fish oil containing EPA and DHA, a high EPA supplement or a placebo daily for 12 weeks. Blood samples collected before and after treatment were evaluated for red blood cell EPA and DHA, the Omega-3 Index and other factors. Omega-3 values increased in both the EPA/DHA and EPA only groups, while the placebo group showed little change. Higher omega-3 Index values were associated with lower cognitive depression scores. Social functioning as evaluated by a general health survey significantly improved with EPA/DHA supplementation and showed a tendency toward improvement in the high EPA group. "This was a study in already depressed individuals, which meant the researchers are looking to high-dose (although it could have been higher) omega-3 supplements to improve depressive symptoms, like a drug," noted coauthor William S. Harris, PhD. "Generally, we think of the function of omega-3s as preventative rather than as treatment. If used as treatment, the dose must be fairly high (4 grams is a typical 'drug' dose) and blood levels must be measured.” Groundbreaking Study Shows Fasting Can Slow Aging, Rebuild Immune System University of Southern California, August 28, 2022 Cutting-edge research reveals that occasionally adopting a diet that mimics the effects of fasting may provide dramatic health benefits. “Fasting flips a regenerative switch essentially regenerating the entire immune system. It gives the OK for stem cells to go begin proliferating and rebuild the entire system,” said Prof Valter Longo, Professor of Gerontology and the Biological Sciences at the University of California. A study, led by USC's Dr. Valter, revealed that a “cycles of a four-day low-calorie diet that mimics fasting (FMD) cut visceral belly fat and elevated the number of progenitor and stem cells in several organs of old mice — including the brain, where it boosted neural regeneration and improved learning and memory,” according to USC News. Dr. Longo notes that strict fasting can be difficult for people to adhere to, and also has the potential to be dangerous, while pointing out that a fasting mimicking diet is much safer and easier. “Strict fasting is hard for people to stick to, and it can also be dangerous, so we developed a complex diet that triggers the same effects in the body,” said Longo, Edna M. Jones Professor of Biogerontology at the USC Davis School of Gerontology and director of the USC Longevity Institute. “I've personally tried both, and the fasting mimicking diet is a lot easier and also a lot safer.” The fasting mimicking diet cuts a person's daily caloric intake over the fasting period down to 34 to 54 percent of their daily average, with a specific balance of micronutrients, fats, carbohydrates, and proteins. In previous groundbreaking research, Longo has shown how fasting can protect immune and other cells from chemotherapy toxicity, while simultaneously starving out cancer cells. Fasting for seventy-two hours protected cancer patients against the toxic impact of chemotherapy: “The good news is the body got rid of the parts in the system which might be damaged or old and inefficient parts, during the fasting. If you start with a system heavily damaged by chemotherapy or aging, fasting cycles can generate, literally, a new immune system,” he said. “It's about reprogramming the body so it enters a slower aging mode, but also rejuvenating it through stem cell-based regeneration,” Longo said. “It's not a typical diet because it isn't something you need to stay on.” “If the results remain as positive as the current ones, I believe this FMD will represent the first safe and effective intervention to promote positive changes associated with longevity and health span, which can be recommended by a physician,” Longo told USC News. “We will soon meet with FDA officers to pursue several FDA claims for disease prevention and treatment.” “Micro-breaks” from tasks show promise in boosting wellbeing West University of Timioara (Romania), August 31, 2022 A review of 22 previously published studies suggests that taking micro-breaks—discontinuing a task for periods of 10 minutes or less—is generally associated with reduced fatigue and increased vigor. Patricia Albulescu of the West University of Timioara, Romania, and colleagues present these findings in the open-access journal PLOS ONE . Concerns are rising over the heavy workloads and long shifts faced by many employees currently in the work force. An increasing number of studies explore various aspects of employee energy management and recovery, often focused on recovery after the workday is over. However, the potential effects of recovery processes during the workday remain unclear. To improve understanding, Albulescu and colleagues conducted a meta-analysis of 22 studies from 19 manuscripts published within the last 30 years, all of which examined the potential benefits of taking micro-breaks from assigned tasks. Tasks varied between experiments and included work simulations, real work-related tasks, and non-work-related cognitive tests. Types of breaks varied as well, including physical breaks, relaxing activities, and more engaging activities, such as watching videos. Statistical analysis of the combined study results revealed an overall association between micro-breaks, higher levels of vigor, and lower fatigue in participants, suggesting that micro-breaks may contribute to wellbeing. These findings support micro-breaks as a potential strategy for boosting wellbeing in the workplace. However, when it comes to job performance, longer breaks may be needed for recovery from more cognitively demanding tasks. Future research could investigate longer breaks as well as address other remaining questions, such as optimal activities to engage in during a micro-break. Mindfulness training improves diabetes symptoms and blood sugar levels VA Healthcare System in Pittsburg, August 24, 2022 It's easy to let current circumstances in our lives dictate our thoughts and feelings. When a problem arises, if we get sick, we are quick to blame it on anything but ourselves. In this way, we are undermining the power of our own thoughts and intentions at work, in us and around us, guiding our present reality. Instead of letting negative circumstances and illness just happen to us, we should embrace the power of mindfulness, allowing ourselves to instead happen to the universe around us. The awareness of our bodily functions, our breathing, our thinking, our motives and the way we treat others helps us be mindful and aware, putting us in the driver seat of determining our paths through life. Research recently presented at the American Association of Diabetes Educators Annual Meeting & Exhibition showed that positive mindfulness training can help improve diabetes symptoms and blood sugar levels. The research was carried out on 28 veterans with type 1 and type 2 diabetes at the VA Healthcare System in Pittsburgh, Pennsylvania, as part of the Mindful Stress Reduction in Diabetes Education program (Mind-STRIDE). Diabetes-related stress falls significantly in veterans during mindfulness training and deep breathing meditation Veterans' glucose levels drop dramatically as diabetes-related distress falls 41 percent The changes over the course of the training were significant. Three months after mindfulness training, diabetes-related distress for all 28 veterans fell 41 percent! A1C levels dropped significantly, almost measuring under the ideal 7.0 range. They went from 8.3 before the mindfulness training to 7.3 after the classes. On top of that, veterans completed diabetes self-management goals with more efficiency after the training. They were better problem solvers, began to eat healthier, were more active and coped better with stress. An Oral Combination of Vitamins A, C, E, and Mg++ Improves hearing University of Castilla (Spain), August 28, 2022 According to news reporting originating in Albacete, Spain,research stated, "The increasing rate of age-related hearing loss (ARHL), with its subsequent reduction in quality of life and increase in health care costs, requires new therapeutic strategies to reduce and delay its impact. The goal of this study was to determine if ARHL could be reduced in a rat model by administering a combination of antioxidant vitamins A, C, and E acting as free radical scavengers along with Mg, a known powerful cochlear vasodilator (ACEMg)." The news reporters obtained a quote from the research from the University of Castilla, "Toward this goal, young adult, 3 month-old Wistar rats were divided into two groups: one was fed with a diet composed of regular chow ('normal diet,' ND); the other received a diet based on chow enriched in ACEMg ('enhanced diet,' ED). Auditory brainstem recordings (ABR) were performed at 0.5, 1, 2, 4, 8, 16, and 32 kHz at 3, 6-8, and 12-14 months of age. No differences were observed at 3 months of age, in both ND and ED animals. At 6-8 and 12-14 months of age there were significant increases in auditory thresholds and a reduction in the wave amplitudes at all frequencies tested, compatible with progressive development of ARHL. However, at 6-8 months threshold shifts in ED rats were significantly lower in low and medium frequencies, and wave amplitudes were significantly larger at all frequencies when compared to ND rats. In the oldest animals, differences in the threshold shift persisted, as well as in the amplitude of the wave II, suggesting a protective effect of ACEMg on auditory function during aging." According to the news reporters, the research concluded: "These findings indicate that oral ACEMg may provide an effective adjuvant therapeutic intervention for the treatment of ARHL, delaying the progression of hearing impairment associated with age." Scientists use 'sleep age' to infer long-term health Stanford University, September 1, 2022 Sleep age is a projected age that correlates to one's health based on their quality of sleep. So for instance, if you analyze the sleep characteristics of dozens of 55-year-olds and average them out, you'll have an idea of what sleep looks like at that age. For instance, someone who's 55 and sleeps soundly through the night with good quality REM cycles could, theoretically, might have a sleep age of 45. Sleep expert Emmanuel Mignot, MD, Ph.D., and his colleagues analyzed some 12,000 studies, each of which focused on an individual, that reported characteristics of their sleep—such as chin and leg movement, breathing and heartbeat. Their goal was to develop a system that assigns one's sleep age and, using machine learning, identifies the variations in sleep most closely linked to mortality. I spoke with Mignot, who has studied sleep for 30 years, about why sleep age is important, how it's calculated and what the study's findings imply about our health. Why study sleep age? When you sleep, you're disconnected from sensory inputs—you're, ideally, not being bothered by the noisy external world or bright lights. During sleep, it's not just the brain that's going through an automatic program, but heart rate and breathing also change, and variations in these can be early predictors of a health disturbance. We spend about a third of our lives sleeping, so it's a substantial component of our general well-being. It's well known that, in pretty much any disorder, sleep is one of the first things that is disturbed. For example, about five or 10 years before other symptoms appear in Parkinson's disease patients, a specific sleep disturbance occurs during which the patient violently acts out dreams, shouts or punches into a wall. What was the most important finding from the study? Our main finding was that sleep fragmentation—when people wake up multiple times throughout the night for less than a minute without remembering it—was the strongest predictor of mortality. Though we see a link in the data, how it contributes to mortality is unknown. This is different from a person realizing they were waking up, which happens during sleep disorders such as insomnia. Determining why sleep fragmentation is so detrimental to health is something we plan to study in the future. Can we measure our own sleep age? Can it be improved? The code is available for physicians and researchers, but the average person would likely have trouble running it through a computer. Regardless, it's not deterministic. There is enormous variation. Even if you have an older sleep age than your chronological age, it doesn't mean that your mortality risk is going to be higher. You see people chain smoking and drinking alcohol at 90 years old and you wonder, "How is this person surviving so long?" There is always huge natural variation. Going to bed and waking up at regular hours is a key to improving your sleep. This means not oversleeping but ensuring you're fully rested. It's a different amount for everyone and often the window varies slightly—for example, being a night owl versus an early bird. Getting solid light exposure—preferably with outside light—during the day, keeping the sleep environment dark at night, exercising regularly but not too close to bedtime, not drinking alcohol and caffeine around bedtime, and avoiding heavy nighttime meals all contribute to healthy sleep. And, of course, make sure any sleep disorder is treated. We found that people with older sleep ages compared to their actual age are at an increased risk of mortality, based on the sleep of patients who later died. From other studies, we know that poor sleep is found in a variety of conditions such as sleep apnea, neurodegeneration, obesity and chronic pain. How poor sleep causes, exacerbates or results from these conditions is unknown.
"Aaron Rodgers Says Use of Psychedelic Helped Him Earn Recent MVPs" - USA TodayMy thoughts on the articlePodcast Aubrey MarcusWhat is ayahuasca?Ergogenic benefit?Long-term benefits?How does ayahuasca work?Potential downsides?What is pharmahuasca?Aaron Rodgers goes deeper on ayahuasca experiences, family feudThis episode of the Flex Diet Podcast is brought to you by the Mike T Nelson website. Go to miketnelson.com to find articles, podcasts, and free giveaways on things like "Should you keto?" and access to my daily fitness insider newsletter.Flex Diet Episode 111: My Plant Medicine Experience w Ayahuasca and Kambo in Costa RicaReferencesBrito-da-Costa AM, Dias-da-Silva D, Gomes NGM, Dinis-Oliveira RJ, Madureira-Carvalho Á. Toxicokinetics and Toxicodynamics of Ayahuasca Alkaloids N,N-Dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact. Pharmaceuticals (Basel). 2020 Oct 23;13(11):334. doi: 10.3390/ph13110334. PMID: 33114119; PMCID: PMC7690791.Callaway JC, McKenna DJ, Grob CS, Brito GS, Raymon LP, Poland RE, Andrade EN, Andrade EO, Mash DC. Pharmacokinetics of Hoasca alkaloids in healthy humans. J Ethnopharmacol. 1999 Jun;65(3):243-56. doi: 10.1016/s0378-8741(98)00168-8. PMID: 10404423.Colaço CS, Alves SS, Nolli LM, Pinheiro WO, de Oliveira DGR, Santos BWL, Pic-Taylor A, Mortari MR, Caldas ED. Toxicity of ayahuasca after 28 days daily exposure and effects on monoamines and brain-derived neurotrophic factor (BDNF) in brain of Wistar rats. Metab Brain Dis. 2020 Jun;35(5):739-751. doi: 10.1007/s11011-020-00547-w. Epub 2020 Feb 27. Erratum in: Metab Brain Dis. 2021 Dec;36(8):2603-2604. PMID: 32103409.Dos Santos RG, Bouso JC, Hallak JEC. Ayahuasca, dimethyltryptamine, and psychosis: a systematic review of human studies. Ther Adv Psychopharmacol. 2017 Apr;7(4):141-157. doi: 10.1177/2045125316689030. Epub 2017 Feb 23. PMID: 28540034; PMCID: PMC5433617.McKenna DJ, Towers GH, Abbott F. Monoamine oxidase inhibitors in South American hallucinogenic plants: tryptamine and beta-carboline constituents of ayahuasca. J Ethnopharmacol. 1984 Apr;10(2):195-223. doi: 10.1016/0378-8741(84)90003-5. PMID: 6587171.Osório Fde L, Sanches RF, Macedo LR, Santos RG, Maia-de-Oliveira JP, Wichert-Ana L, Araujo DB, Riba J, Crippa JA, Hallak JE. Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report. Braz J Psychiatry. 2015 Jan-Mar;37(1):13-20. doi: 10.1590/1516-4446-2014-1496. PMID: 25806551.Palhano-Fontes F, Barreto D, Onias H, Andrade KC, Novaes MM, Pessoa JA, Mota-Rolim SA, Osório FL, Sanches R, Dos Santos RG, Tófoli LF, de Oliveira Silveira G, Yonamine M, Riba J, Santos FR, Silva-Junior AA, Alchieri JC, Galvão-Coelho NL, Lobão-Soares B, Hallak JEC, Arcoverde E, Maia-de-Oliveira JP, Araújo DB. Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial. Psychol Med. 2019 Mar;49(4):655-663. doi: 10.1017/S0033291718001356. Epub 2018 Jun 15. PMID: 29903051; PMCID: PMC6378413.Palhano-Fontes F, Soares BL, Galvão-Coelho NL, Arcoverde E, Araujo DB. Ayahuasca for the Treatment of Depression. Curr Top Behav Neurosci. 2021 Nov 11. doi: 10.1007/7854_2021_277. Epub ahead of print. PMID: 34761362.Rivier, L., & Lindgren, J. E. (1972). “Ayahuasca,” the South American hallucinogenic drink: An ethnobotanical and chemical investigation. Economic Botany, 26(2), 101-129.Sanches RF, de Lima Osório F, Dos Santos RG, Macedo LR, Maia-de-Oliveira JP, Wichert-Ana L, de Araujo DB, Riba J, Crippa JA, Hallak JE. Antidepressant Effects of a Single Dose of Ayahuasca in Patients With Recurrent Depression: A SPECT Study. J Clin Psychopharmacol. 2016 Feb;36(1):77-81. doi: 10.1097/JCP.0000000000000436. PMID: 26650973.Winstock AR, Kaar S, Borschmann R. Dimethyltryptamine (DMT): prevalence, user characteristics and abuse liability in a large global sample. J Psychopharmacol. 2014 Jan;28(1):49-54. doi: 10.1177/0269881113513852. Epub 2013 Nov 27. PMID: 24284475.DisclaimerMike T Nelson is a PhD and not a physician or registered dietitian. The contents here should not be taken as medical advice. It is not intended to diagnose, treat, cure, or prevent any health problem - nor is it intended to replace the advice of a physician. Always consult your physician or qualified health professional on any matters regarding your health. This is for entertainment purpose only. Psychedelics are classified as Schedule 1 Controlled Substances by the DEA, and not approved by the FDA for any accepted medical use or prescription.
Antihypertensive and antioxidant activity in black beans National Polytechnic Institute (Mexico) 16 July 2022 Beans are one of the most important crops for the Mexican population due to its nutritional qualities. In fact, the country is one of the top 10 producers of this legume in the world, and several studies have reflected the correlation between consumption and decreased chronic degenerative diseases, cardiovascular diseases, obesity and diabetes. Therefore, the National School of Biological Sciences of the National Polytechnic Institute (IPN-ENCB), conducted an investigation to evaluate the antioxidant and antihypertensive activity in black beans, and found that in addition to these qualities, proteins in the bean can remove heavy metals from the body. The polytechnic research identified bioactive peptides in the legume that have a beneficial effect as antihypertensive and antioxidant, which could favor the prevention and treatment of cardiovascular diseases, with a specific effect on blood pressure and oxidative stress. It was determined that fasolina and lectin hydrolysates (main proteins in the Jamapa black bean) had chelating activity (removal of heavy metals in the body) and, when hydrolyzed with pepsin-pancratin, they release peptides (amino acids) with antihypertensive and antioxidant effects. Could Eating Fruit More Often Keep Depression At Bay? Aston University (UK), July 15, 2022 People who frequently eat fruit are more likely to report greater positive mental well-being and are less likely to report symptoms of depression than those who do not, according to new research from the College of Health and Life Sciences, Aston University The study found frequent fruit eaters had greater positive mental wellbeing The study surveyed 428 adults and looked at the relationship between their consumption of fruit, vegetables, sweet and savoury food snacks and their psychological health The more often people ate fruit, the lower they scored for depression and the higher for mental well-being. Published in the British Journal of Nutrition, the study surveyed 428 adults from across the UK and looked at the relationship between their consumption of fruit, vegetables, sweet and savoury food snacks, and their psychological health. People who frequently snacked on nutrient-poor savoury foods (such as crisps) were more likely to experience 'everyday mental lapses' (known as subjective cognitive failures) and report lower mental wellbeing. A greater number of lapses, was associated with higher reported symptoms of anxiety, stress and depression, and lower mental wellbeing scores. Effect of Short-term Quercetin, Caloric Restriction in Late Life Effective to Counter Age-Related Oxidative Macromolecular Damage. Pondicherry University (India), July 13, 2022 According to news from Pondicherry, India, research stated, "Aging is characterized by gradual accumulation of macromolecular damage leading to progressive loss of physiological function and increased susceptibility to diverse diseases. Effective anti-aging strategies involving caloric restriction or antioxidant supplementation are receiving growing attention to attenuate macromolecular damage in age associated pathology." Research from Pondicherry University, "In the present study, we for the first time investigated the effect of quercetin, caloric restriction and combined treatment (caloric restriction with quercetin) on oxidative stress parameters, acetylcholinesterase and ATPases enzyme activities in the cerebral cortex of aged male Wistar rats. Our results demonstrate that combined treatment of caloric restriction and quercetin significantly improved the age associated decline in the activities of endogenous antioxidant enzymes [such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)] and glutathione (GSH), and nitric oxide (NO). According to the news reporters, the research concluded: "Finally, we conclude that combined treatment of caloric restriction and quercetin in late life is an effective anti-aging therapy to counteract the age related accumulation of oxidative macromolecular damage." How Drinking Soda on a Hot Day Can Damage Kidneys, Leading to Diabetes, Heart Disease University of Buffalo, July 18, 2022 Research demonstrates the acute deleterious effects soda can have on your kidney function when used to quench your thirst during exertion on a hot day. Drinking soda causes dehydration and raises markers for kidney disease when consumed after performing manual labor or exercise in 95-degree Fahrenheit weather. When you exert yourself in a hot environment, your body regulates blood pressure and conserves water by reducing blood flow to your kidneys. A sudden and steep drop in blood flow through your kidneys can cause acute kidney injury due to the fact that it reduces the amount of oxygen being delivered to your kidneys. Your diet has an overriding influence over the health of your kidneys, with sugar and excess protein topping the list of food components known to cause problems when consumed regularly. The study, published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, found soda caused dehydration and raised markers for kidney disease when consumed after performing manual labor in 95-degree F. weather. “The volunteers completed … a 30-minute treadmill workout followed by three different five-minute lifting, dexterity and sledgehammer swinging activities. After 45 minutes of exercise, the volunteers rested for 15 minutes … while drinking 16 ounces of either a high-fructose, caffeinated soft drink or water. After the break, they repeated the cycle three more times for a total of four hours. Before leaving the laboratory, the volunteers were given more of their assigned beverages to drink before consuming any further fluids. The volume was either 1 liter or a volume equal to 115% of their body weight lost through sweating if that amount was greater.” When volunteers drank soda, 75% of them had elevated levels of creatinine in their blood, a marker for kidney injury. Only 8% of participants in the water trial had elevated creatinine. When drinking soda, volunteers also had: A lower glomerular filtration rate, another marker for kidney injury Higher uric acid levels Mild dehydration Higher levels of vasopressin, an antidiuretic hormone that raises blood pressure Black Seed Oil Extract Causes Oral Cancer Cells To Self-Destruct Institute of Biochemistry and Biotechnology (Taiwan), July 20, 2022 A range of chemotherapeutic options for treating cancer are available, however many of the treatments are themselves associated with significant morbidity and mortality. Today many cancer sufferers search for alternatives to conventional chemotherapy. Increasingly natural alternative options are becoming available, often with little or no side-effects and concrete science is proving the effects of many natural substances against cancer. One substance which is increasingly making the headlines is thymoquinone, an active component of Nigella sativa or black seed oil. Scientists from the Institute of Biochemistry and Biotechnology, Taiwan, have found that this remarkable compound elicits cytotoxic effects on various squamous cancer cell lines through various mechanisms. The study examined a highly malignant strain of squamous cell carcinoma, which was taken from various patients with oral cancer; this particular cancer type also causes many other cancers of the head and neck. The cell lines were grown in a lab and treated with different concentrations of thymoquinone. The results showed that after just 24 hours of treatment there was a significant concentration-dependent cytotoxic effect on these cells. The study further examined why this was happening. Their findings are quite remarkable as they were able to demonstrate that thymoquinone was a potent inhibitor of oral cancer cell viability via two distinct anti-neoplastic mechanisms. No bones about it: Cannabis may be used to treat fractures Tel Aviv University researcher finds non-psychotropic compound in marijuana can help heal bone fissures Tel Aviv University (Israel), July 19, 2022 A study published in the Journal of Bone and Mineral Research by Tel Aviv University and Hebrew University researchers explores another promising new medical application for marijuana. According to the research, the administration of the non-psychotropic component cannabinoid cannabidiol (CBD) significantly helps heal bone fractures. The study, conducted on rats with mid-femoral fractures, found that CBD -- even when isolated from tetrahydrocannabinol (THC), the major psychoactive component of cannabis -- markedly enhanced the healing process of the femora after just eight weeks. Undeniable clinical potential The same team, in earlier research, discovered that cannabinoid receptors within our bodies stimulated bone formation and inhibited bone loss. This paves the way for the future use of cannabinoid drugs to combat osteoporosis and other bone-related diseases. "We found that CBD alone makes bones stronger during healing, enhancing the maturation of the collagenous matrix, which provides the basis for new mineralization of bone tissue," said Dr. Gabet. "After being treated with CBD, the healed bone will be harder to break in the future." The researchers injected one group of rats with CBD alone and another with a combination of CBD and THC. After evaluating the administration of THC and CBD together in the rats, they found CBD alone provided the necessary therapeutic stimulus. OCCUPY PEACE & FREEDOM RALLY INFO Saturday, July 23 -- 2:00 pm Kingston, NY (at the historical 4 corners -- Crown and John Streets) Speakers: Gerald Celente Judge Andrew Napolitano Gary Null Scott Ritter Phil Giraldi (former CIA official) Live music, food and drink
© 2020-2025 Ivy Podcast Discovery LLC
