Podcasts about scientific discovery

Fr. Spitzer and Doug discuss the theory of evolution, whether there are parameters for which Catholics can believe in this theory, and how unique transphysical souls play a part.

We are together in South Bend and teach a class to PhD students in the Mendoza College of Business at the University of Notre Dame. Our joint teaching experience makes us wonder: What should all doctoral students learn or what should we all teach the next generation of IS students? We come up with Nick's rules for a good PhD education: First, understand what knowledge and inferences are. Second, learn different methods and then deep dive into a primary method. Third, pick a domain and learn its foundations and history. Fourth, develop a mindset of mastery to become the world's expert on your topic. And finally, develop and hone your writing skills.  Episode reading list Bacon, F. (1620/2019). Novum Organum. Anodos. Hume, D. (1748/1998). An Enquiry Concerning Human Understanding. In J. Perry & M. E. Bratman (Eds.), Introduction to Philosophy: Classical and Contemporary Readings (3rd ed., pp. 190-220). Oxford University Press. Popper, K. R. (1959). The Logic of Scientific Discovery. Basic Books. Yin, R. K. (2009). Case Study Research: Design and Methods (4th ed.). Sage Publications. Berente, N., Ivanov, D., & Vandenbosch, B. (2007). Process Compliance and Enterprise Systems Implementation. In: Proceedings of the 40th Annual Hawaii International Conference on System Sciences. Waikoloa, Hawaii, pp. 222-231. Castelo, N., Bos, M. W., & Lehmann, D. R. (2019). Task-Dependent Algorithmic Aversion. Journal of Marketing Research, 56(5), 809-825. Recker, J. (2021). Scientific Research in Information Systems: A Beginner's Guide (2nd ed.). Springer. Mackie, J. L. (1965). Causes and Conditions. American Philosophical Quarterly, 2(4), 245-264. Gable, G. G. (1994). Integrating Case Study and Survey Research Methods: An Example in Information Systems. European Journal of Information Systems, 3(2), 112-126. Chalmers, A. F. (2013). What Is This Thing Called Science? (4th ed.). Hackett. Shadish, W. R., Cook, T. D., & Campbell, D. T. (2001). Experimental and Quasi-Experimental Designs for Generalized Causal Inference (2nd ed.). Houghton Mifflin. Taylor, F. W. (1911). The Principles of Scientific Management. Harper and Bros. March, J. G., & Simon, H. A. (1958). Organizations. John Wiley & Sons. Nelson, R. R., & Winter, S. G. (1982). An Evolutionary Theory of Economic Change. Harvard University Press. 

From innovation pipeline movement to Series B funding, leadership changes and so much more, BiomEdit is on the move. This week, CEO Aaron Schacht joins Agbioscience to talk scientific discovery, artificial intelligence, creating “and” solutions and how he approaches adding to his team in a meaningful way. Highlights include:  An overview of BiomEdit's innovation pipeline and what has Aaron most excited right now Optavant – BE-101 – and its movement through the USDA regulatory process, what the technology is designed to do and its benefit to the poultry industry Creating solutions that establish certainty for producers – having the economics make sense to where they can realize the full genetic potential of the animal Finding the right messages to connect consumers to straightforward understanding of how their food is produced and why these innovations are so important for them How the BiomEdit team approaches scientific discovery  The company's latest Series B fundriase -- $18.4 M – and what it will enable the company to do New leadership additions and how they add not only competencies, but culture to the BiomEdit team Aaron's vision for the continued opportunity to marry the AI-driven predictive analysis with scientific discovery to drive this work forward – and some incredible updates for their team in this space What's ahead for BiomEdit 

Wednesday 17 September 2025 To hear the fascinating FULL idiscussion, become a MEMBER today and enjoy this and other full featured content.   "Reconquest" is a militant, engaging, and informative Catholic radio program featuring interviews with interesting guests as well as commentary by your host. It is a radio-journalistic extension of the Crusade of Saint Benedict Center.

The 2021 winner of the Nobel Prize in medicine, Ardem Patapoutian speaks of his love for science, why he wishes he had an MD, and the importance of getting out of the lab to inspire young people. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit: https://www.medscape.com/author/bob-harrington Nobel Prize in Physiology or Medicine 2021 https://pubmed.ncbi.nlm.nih.gov/39429349/ https://www.nobelprize.org/prizes/medicine/2021/press-release/ Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels https://pubmed.ncbi.nlm.nih.gov/20813920/ PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex https://doi.org/10.1126/science.aau6324 PIEZO Ion Channels in Cardiovascular Functions and Diseases https://doi.org/10.1161/CIRCRESAHA.123.322798 You may also like: Hear John Mandrola, MD, with his summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

Fr. Spitzer and Doug discuss the “partnership” theory of divine inspiration, noting how the biblical author plays a role in revealed text and is not simply a transcriptionist.

Fr. Spitzer and Doug discuss the reasons why the Bible is not intended to provided scientific facts. They also examine why science should not be used to explain revelation.

Today Joseph Krause and Jorge Colindres of Radical AI join The Cognitive Revolution to discuss their ambitious mission to revolutionize materials science by combining AI-powered discovery engines with fully autonomous robotic laboratories, exploring how they're accelerating the development of breakthrough materials like high-entropy alloys and room temperature superconductors that could unlock hypersonic flight, interplanetary travel, and other transformative technologies. Check out our sponsors: Oracle Cloud Infrastructure, Shopify. Shownotes below brought to you by Notion AI Meeting Notes - try one month for free at ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://⁠⁠notion.com/lp/nathan Material Development Challenges: Current material development faces three major obstacles: costs exceeding $100 million, 10-25 year commercialization timelines, and fragmentation between academic research and corporate R&D. Business Model Approach: Radical AI determined that selling software or licensing materials would be insufficient business models. Instead, they focus on selling materials at scale for high-impact industries. Focus on Processing IP: The real IP value in material science isn't just in composition patents but in the trade secrets of scaling production efficiently and cost-effectively. Public-Private Partnership: Radical AI advocates for government involvement in material science through public-private partnerships, particularly for critical applications in defense, energy, and advanced computing. China's Material Science Approach: China establishes entire manufacturing hubs around new material discoveries to scale production, demonstrating their prioritization of materials as foundational to innovation. Culture of Productive Failure: The company embraces daily failure as a necessary part of innovation, building on these failures to achieve breakthroughs. Sponsors: Oracle Cloud Infrastructure: Oracle Cloud Infrastructure (OCI) is the next-generation cloud that delivers better performance, faster speeds, and significantly lower costs, including up to 50% less for compute, 70% for storage, and 80% for networking. Run any workload, from infrastructure to AI, in a high-availability environment and try OCI for free with zero commitment at https://oracle.com/cognitive Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive

In the second episode on metascience, we discuss the benefits of metascientific study according to Mario Bunge, some key milestones in sociology, psychology, and anthropology of science, and whether there should be a science of the science of science.   Shownotes Galton, F. (1874). English men of science: Their nature and nurture. McMillian & Co. https://archive.org/details/englishmenofscie00galtuoft Latour, B. & Woolgar, S. (1979). Laboratory life: The social construction of scientific facts. Sage Publications.  Candolle, A. de (with Fisher - University of Toronto). (1873). Histoire des sciences et des savants depuis deux siècles; suivie d'autres études sur des sujets scientifiques, en particulier sur la sélection dans l'espèce humaine. Genève, Georg. http://archive.org/details/histoiredesscie00cand Vaesen, K. (2021). French Neopositivism and the Logic, Psychology, and Sociology of Scientific Discovery. HOPOS: The Journal of the International Society for the History of Philosophy of Science, 11(1), 183–200. https://doi.org/10.1086/712934  

Intelligent Design as Fuel for Scientific Discovery (2025 Dallas Conference on Science & Faith). ACU Saturday Series. Geologist Casey Luskin explains how the theory of intelligent design provides fuel for scientific discovery. Dr. Luskin is Associate Director of the Center for Science and Culture at Discovery Institute. Presented at the 2025 Dallas Conference on Science and Faith. Watch this video at-  https://youtu.be/M_4aBu2g8A8?si=jZsh1KbN7CACBAuT Discovery Science 278K subscribers 108,046 views Jul 7, 2025 ============================ Are you interested in the origins of life and the universe? Get this free book and explore the debate between Darwinian evolution and intelligent design. If you're intrigued by the origins of life, this is a must-read. It might change the way you view our world. As a special gift from the director of the CSC, Dr. Stephen Meyer, you can download his 32-page mini-book Scientific Evidence for a Creator for FREE: https://evolutionnews.org/_/sefac The Discovery Science News Channel is the official Youtube channel of Discovery Institute's Center for Science & Culture. The CSC is the institutional hub for scientists, educators, and inquiring minds who think that nature supplies compelling evidence of intelligent design. The CSC supports research, sponsors educational programs, defends free speech, and produce articles, books, and multimedia content. For more information visit: https://www.discovery.org/id/ https://evolutionnews.org/ https://intelligentdesign.org/ Follow us: X:   / discoverycsc   Facebook:   / discoverycsc   Instagram:   / discoverycsc   TikTok:   / discoverycsc   Visit other Youtube channels connected to the Center for Science & Culture Discovery Institute:    / discoveryinstitute   Dr. Stephen C. Meyer:    / drstephenmeyer  

This podcast was created using NotebookLM. This podcast emphasizes the increasing importance of geriatric dentistry due to the aging population and highlights how case reports are fundamental to educating future oral healthcare providers in this field. 

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Yerkes Observatory near Lake Geneva is more than 125 years old, is the site of numerous scientific discoveries, is home the world's largest refracting telescope and has been visited by the likes of Edwin Hubble, Carl Sagan and Albert Einstein.

As global food demand accelerates, the agricultural sector faces rising pressure to innovate faster, safer, and more sustainably. Today's guest on the ‘AI in Business' podcast is Brian Lutz, the Vice President of Agricultural Solutions at Corteva Agriscience, the world's leading pure-play seed and crop protection company. Brian joins Emerj Senior Editor Matthew DeMello to discuss their partnership with Deloitte to drive AI for discovery across biology and chemistry in agriculture. He explains how Corteva integrates AI into every phase of R&D — from genetic optimization in seeds to molecule discovery in crop protection. Want to share your AI adoption story with executive peers? Click emerj.com/expert2 for more information and to be a potential future guest on the ‘AI in Business' podcast! This episode is sponsored by Deloitte. Learn how brands work with Emerj and other Emerj Media options at emerj.com/ad1.

The market for ag biologicals is projected to grow significantly according to Grandview Research – making the leap from $11B market in 2024 to a $16.8B in 2030. One Indiana company has recently created a strategic alliance to drive biological innovation at every stage of the crop nutrition cycle. Dr. Tanya Soule, Vice President of Microbiology at BW Fusion, joins us to talk science, producers and the farm. We get into: What biologicals are and how they benefit farmers How they work in tandem with other fertilizers and modes of crop protection to drive yield BW Fusion's approach to scientific discovery and innovation How the company got into the agbioscience industry – it wasn't its first vertical Bain Capital Double Impact's support that led to the strategic alliance between BW Fusion, Biodyne USA and Agronomy 365 and what that has allowed them to do from an innovation perspective The farmers' role in advancing innovation at BW Fusion Why Tanya, a career academic, made the switch to working with the BW Fusion team and coming to the agbiosciences Her advice for young scientists What's ahead for BW Fusion

The market for ag biologicals is projected to grow significantly according to Grandview Research – making the leap from $11B market in 2024 to a $16.8B in 2030. One Indiana company has recently created a strategic alliance to drive biological innovation at every stage of the crop nutrition cycle. Dr. Tanya Soule, Vice President of Microbiology at BW Fusion, joins us to talk science, producers and the farm. We get into:  What biologicals are and how they benefit farmers How they work in tandem with other fertilizers and modes of crop protection to drive yield BW Fusion's approach to scientific discovery and innovation How the company got into the agbioscience industry – it wasn't its first vertical Bain Capital Double Impact's support that led to the strategic alliance between BW Fusion, Biodyne USA and Agronomy 365 and what that has allowed them to do from an innovation perspective The farmers' role in advancing innovation at BW Fusion Why Tanya, a career academic, made the switch to working with the BW Fusion team and coming to the agbiosciences Her advice for young scientists What's ahead for BW Fusion 

Dr James Keaveney spoke to Mike Wills about the 120th anniversary of Einstein’s Theory of Relativity, what it meant then, why it still matters now, and how it continues to inform science at UCT, CERN, and beyond. Afternoon Drive with John Maytham is the late afternoon show on CapeTalk. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567See omnystudio.com/listener for privacy information.

Much of the scientific process involves searching. But rather than continue to rely on the luck of discovery, Google DeepMind has engineered a more efficient AI agent that mines complex spaces to facilitate scientific breakthroughs. Sarah Guo speaks with Pushmeet Kohli, VP of Science and Strategic Initiatives, and research scientist Matej Balog at Google DeepMind about AlphaEvolve, an autonomous coding agent they developed that finds new algorithms through evolutionary search. Pushmeet and Matej talk about how AlphaEvolve tackles the problem of matrix multiplication efficiency, scaling and iteration in problem solving, and whether or not this means we are at self-improving AI. Together, they also explore the implications AlphaEvolve has to other sciences beyond mathematics and computer science. Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @pushmeet | @matejbalog Chapters: 00:00 Pushmeet Kohli and Matej Balog Introduction 0:48 Origin of AlphaEvolve 02:31 AlphaEvolve's Progression from AlphaGo and AlphaTensor 08:02 The Open Problem of Matrix Multiplication Efficiency 11:18 How AlphaEvolve Evolves Code 14:43 Scaling and Predicting Iterations 16:52 Implications for Coding Agents 19:42 Overcoming Limits of Automated Evaluators 25:21 Are We At Self-Improving AI? 28:10 Effects on Scientific Discovery and Mathematics 31:50 Role of Human Scientists with AlphaEvolve 38:30 Making AlphaEvolve Broadly Accessible 40:18 Applying AlphaEvolve Within Google 41:39 Conclusion

Pacific Northwest National Laboratory (PNNL) draws on signature fundamental capabilities to advance scientific discovery, improve energy resiliency, and enhance national security.  On this podcast episode, Laboratory Director Steven Ashby, Ph.D., discusses key drivers and challenges that are steering the lab's important work regarding grid resiliency and affordability. Ashby also tells our listeners about the new Grid Storage Launchpad, a one-of-a-kind Department of Energy facility to develop and test novel battery concepts at scale in a safe environment. Of course, with all these emerging technologies, there are inherent risks—wildfires, and cyberattacks to name a few. Ashby discusses these risks and the ways PNNL is working together with the industry (including by leveraging novel AI capabilities) to quantify and combat problems that can be addressed by advancing the grid.

My guest is Dr. Jay Bhattacharya, MD, PhD, Director of the National Institutes of Health (NIH) and Professor Emeritus of Health Policy at Stanford University. We discuss which scientific questions ought to be the priority for NIH, how to incentivize bold, innovative science especially from younger labs, how to solve the replication crisis and restore trust and transparency in science and public health, including acknowledging prior failures by the NIH. We discuss the COVID-19 pandemic and the data and sociological factors that motivated lockdowns, masking and vaccine mandates. Dr. Bhattacharya shares his views on how to resolve the vaccine–autism debate and how best to find the causes and cures for autism and chronic diseases. The topics we cover impact everyone: male, female, young and old and, given that NIH is the premier research and public health organization in the world, extend to Americans and non-Americans alike. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Levels: ⁠https://levels.link/huberman⁠ LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Jay Bhattacharya 00:06:56 National Institutes of Health (NIH), Mission 00:09:12 Funding, Basic vs. Applied Research 00:18:22 Sponsors: David & Eight Sleep 00:21:20 Indirect Costs (IDC), Policies & Distribution 00:30:43 Taxpayer Funding, Journal Access, Public Transparency 00:38:14 Taxpayer Funding, Patents; Drug Costs in the USA vs Other Countries 00:48:50 Reducing Medication Prices; R&D, Improving Health 01:00:01 Sponsors: AG1 & Levels 01:02:55 Lowering IDC?, Endowments, Monetary Distribution, Scientific Groupthink 01:12:29 Grant Review Process, Innovation 01:21:43 R01s, Tenure, Early Career Scientists & Novel Ideas 01:31:46 Sociology of Grant Evaluation, Careerism in Science, Failures 01:39:08 “Sick Care” System, Health Needs 01:44:01 Sponsor: LMNT 01:45:33 Incentives in Science, H-Index, Replication Crisis 01:58:54 Scientists, Data Fraud, Changing Careers 02:03:59 NIH & Changing Incentive Structure, Replication, Pro-Social Behavior 02:15:26 Scientific Discovery, Careers & Changing Times, Journals & Publications 02:19:56 NIH Grants & Appeals, Under-represented Populations, DEI 02:28:58 Inductive vs Deductive Science; DEI & Grants; Young Scientists & NIH Funding 02:39:38 Grant Funding, Identity & Race; Shift in NIH Priorities 02:51:23 Public Trust & Science, COVID Pandemic, Lockdowns, Masks 03:04:41 Pandemic Mandates & Economic Inequality; Fear; Public Health & Free Speech 03:13:39 Masks, Harms, Public Health Messaging, Uniformity, Groupthink, Vaccines 03:22:48 Academic Ostracism, Public Health Messaging & Opposition 03:30:26 Culture of American Science, Discourse & Disagreement 03:36:03 Vaccines, COVID Vaccines, Benefits & Harms 03:47:05 Vaccine Mandates, Money, Public Health Messaging, Civil Liberties 03:54:52 COVID Vaccines, Long-Term Effects; Long COVID, Vaccine Injury, Flu Shots 04:06:47 Do Vaccines Cause Autism?; What Explains Rise in Autism 04:18:33 Autism & NIH; MAHA & Restructuring NIH? 04:25:47 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Can a Nobel Prize-winning molecule help slow aging, improve sleep, and boost your energy?In this episode of Better Health Bookshelf, host Mike Capuzzi speaks with Chris Burres, scientist, entrepreneur, and author of Live Longer and Better, about the surprising health benefits of carbon 60—a powerful antioxidant gaining attention as a next-generation longevity supplement. For adults over 50 seeking alternatives to pharmaceutical solutions, this conversation explores what carbon 60 supplements (also known as C60) can really do for energy, inflammation, and healthy aging.Listeners will discover:• What carbon 60 is and why it matters for longevity • The link between C60, oxidative stress, and better sleep • How carbon 60 may support healthy aging from head to toeLearn why more people over 50 are turning to this promising discovery and what it could mean for your health.If you find this episode helpful, please consider subscribing and sharing it with friends and family.

MIT says that due to concerns about the “integrity” of a high-profile paper on the effects of artificial intelligence on the productivity of a materials science lab, the paper should be “withdrawn from public discourse.” The paper in question, “Artificial Intelligence, Scientific Discovery, and Product Innovation,” was written by a doctoral student Learn more about your ad choices. Visit podcastchoices.com/adchoices

The search for life beyond Earth is no longer science fiction—it takes a lot of data, powerful telescopes and a bit of cosmic detective work. And at the center of this search is University of Chicago astrophysicist Jacob Bean. Bean was part of the team that made history by detecting carbon dioxide in the atmosphere of a distant planet using the James Webb Space Telescope—a major step forward in our ability to study exoplanets.Bean uses cutting-edge tools and discoveries that are reshaping how we think about planet habitability, biosignatures and our place in the universe. From potentially habitable exoplanets like K2-18b to false hopes like Gliese 486b, Bean shares why the atmospheres of these faraway worlds might hold the key to one of humanity's oldest questions: Are we alone in the universe?

Hundreds of U.S.-based scientists are applying to a French university program following major federal research funding cuts in the U.S. France's new initiative promises financial support and academic freedom, prompting what some are calling a potential “brain drain.” The panel discusses the implications for American innovation, global collaboration, and the growing politicization of science funding.News SourceNPR by Alana Wise, April 18, 2025https://www.npr.org/2025/04/18/nx-s1-5368132/us-researchers-scientists-apply-french-university-programThe Non-Prophets, Episode 24.18.2 featuring Cynthia McDonald, Stephen Harder and AJ FranceAttracts U.S. Scientists After Research Cuts

In this episode of For Your Innovation, Brett Winton, along with ARK Invest Chief Investment Strategist, Charles Roberts, and Research Analyst, Nemo Marjanovic, sit down with Geoffrey von Maltzahn, CEO and founder of Lila Sciences and a general partner at Flagship Pioneering. Fresh out of stealth mode, Lila is pioneering the concept of scientific superintelligence—leveraging AI and automation to accelerate discovery across materials science, chemistry, and life sciences. Geoffrey shares his vision for transforming the scientific method into an AI-driven engine that pushes the boundaries of innovation at unprecedented speeds. The conversation explores the limitations of traditional scientific research, the role of AI-driven autonomous labs, and how Lila aims to revolutionize hypothesis testing and experimentation. Geoffrey discusses how scientific intelligence can scale across domains, the importance of proprietary data, and why unlocking AI's potential in science could be one of the most valuable technological advances of our time.Key Points From This Episode:ARK Invest sees Lila as a transformative opportunity.Lila's AI science factories are reinventing research.We're experiencing breakthroughs in mRNA and material science through AI.Scientists roles are evolving in an AI-powered world.

Is it okay to use large language models in the research process? For what task, exactly, and to automate the task or to augment the researcher? In this episode, we try to explore whether and how LLMs could be used in five aspects of the research process - for paper writing, reviewing, data analysis, as a subject of research, or as a surrogate for research subjects. We also discuss whether they should be used at all, and what some long-term consequences could be of such a choice, and we develop a number of heuristic rules to help researcher make decisions about using LLMs for research. Episode reading list Kankanhalli, A. (2024). Peer Review in the Age of Generative AI. Journal of the Association for Information Systems, 25(1), 76-84. Yang, Y., Duan, H., Liu, J., & Tam, K. Y. (2024). LLM-Measure: Generating Valid, Consistent, and Reproducible Text-Based Measures for Social Science Research. arXiv preprint, . Li, J., Larsen, K. R. T., & Abbasi, A. (2020). TheoryOn: A Design Framework and System for Unlocking Behavioral Knowledge Through Ontology Learning. MIS Quarterly, 44(4), 1733-1772. Larsen, K. R., Yan, S., & Lukyanenko, R. (2024). LLMs and Psychometrics: Global Construct Validity Integrating LLMs and Psychometrics. 45th International Conference on Information Systems, Bangkok, Thailand. Anthis, J. R., Liu, R., Richardson, S. M., Kozlowski, A. C., Koch, B., Evans, J., Brynjolfsson, E., & Bernstein, M. (2025). LLM Social Simulations Are a Promising Research Method. arXiv preprint, . Abbasi, A., Somanchi, S., & Kelley, K. (2025). The Critical Challenge of using Large-scale Digital Experiment Platforms for Scientific Discovery. MIS Quarterly, 49(1), 1-28.

In this episode of Crazy Wisdom, Stewart Alsop speaks with German Jurado about the strange loop between computation and biology, the emergence of reasoning in AI models, and what it means to "stand on the shoulders" of evolutionary systems. They talk about CRISPR not just as a gene-editing tool, but as a memory architecture encoded in bacterial immunity; they question whether LLMs are reasoning or just mimicking it; and they explore how scientists navigate the unknown with a kind of embodied intuition. For more about German's work, you can connect with him through email at germanjurado7@gmail.com.Check out this GPT we trained on the conversation!Timestamps00:00 - Stewart introduces German Jurado and opens with a reflection on how biology intersects with multiple disciplines—physics, chemistry, computation.05:00 - They explore the nature of life's interaction with matter, touching on how biology is about the interface between organic systems and the material world.10:00 - German explains how bioinformatics emerged to handle the complexity of modern biology, especially in genomics, and how it spans structural biology, systems biology, and more.15:00 - Introduction of AI into the scientific process—how models are being used in drug discovery and to represent biological processes with increasing fidelity.20:00 - Stewart and German talk about using LLMs like GPT to read and interpret dense scientific literature, changing the pace and style of research.25:00 - The conversation turns to societal implications—how these tools might influence institutions, and the decentralization of expertise.30:00 - Competitive dynamics between AI labs, the scaling of context windows, and speculation on where the frontier is heading.35:00 - Stewart reflects on English as the dominant language of science and the implications for access and translation of knowledge.40:00 - Historical thread: they discuss the Republic of Letters, how the structure of knowledge-sharing has evolved, and what AI might do to that structure.45:00 - Wrap-up thoughts on reasoning, intuition, and the idea of scientists as co-evolving participants in both natural and artificial systems.50:00 - Final reflections and thank-yous, German shares where to find more of his thinking, and Stewart closes the loop on the conversation.Key InsightsCRISPR as a memory system – Rather than viewing CRISPR solely as a gene-editing tool, German Jurado frames it as a memory architecture—an evolved mechanism through which bacteria store fragments of viral DNA as a kind of immune memory. This perspective shifts CRISPR into a broader conceptual space, where memory is not just cognitive but deeply biological.AI models as pattern recognizers, not yet reasoners – While large language models can mimic reasoning impressively, Jurado suggests they primarily excel at statistical pattern matching. The distinction between reasoning and simulation becomes central, raising the question: are these systems truly thinking, or just very good at appearing to?The loop between computation and biology – One of the core themes is the strange feedback loop where biology inspires computational models (like neural networks), and those models in turn are used to probe and understand biological systems. It's a recursive relationship that's accelerating scientific insight but also complicating our definitions of intelligence and understanding.Scientific discovery as embodied and intuitive – Jurado highlights that real science often begins in the gut, in a kind of embodied intuition before it becomes formalized. This challenges the myth of science as purely rational or step-by-step and instead suggests that hunches, sensory experience, and emotional resonance play a crucial role.Proteins as computational objects – Proteins aren't just biochemical entities—they're shaped by information. Their structure, function, and folding dynamics can be seen as computations, and tools like AlphaFold are beginning to unpack that informational complexity in ways that blur the line between physics and code.Human alignment is messier than AI alignment – While AI alignment gets a lot of attention, Jurado points out that human alignment—between scientists, institutions, and across cultures—is historically chaotic. This reframes the AI alignment debate in a broader evolutionary and historical context, questioning whether we're holding machines to stricter standards than ourselves.Standing on the shoulders of evolutionary processes – Evolution is not just a backdrop but an active epistemic force. Jurado sees scientists as participants in a much older system of experimentation and iteration—evolution itself. In this view, we're not just designing models; we're being shaped by them, in a co-evolution of tools and understanding.

Send us a textFrom the Front Lines to the Lab: Dino Garner's Extraordinary Journey of Service, Science, and SupportIn this captivating episode of Security Halt!, host Deny Caballero sits down with Dino Garner—veteran, innovator, author, and scientist—for a wide-ranging conversation on mentorship, resilience, and redefining purpose after military service.Dino opens up about his remarkable life—from growing up in Europe and navigating cultural transitions in the U.S., to serving in the military and later making groundbreaking discoveries in marine biology and scientific research. He emphasizes the critical role of mentorship, personal development, and helping others as guiding principles throughout his life.Together, they unpack the struggles many veterans face when returning to civilian life, the need for lifelong learning, and how innovation and empathy can drive new solutions for PTSD. Dino also shares compelling insights about the molecular side of trauma and why deeper scientific understanding is essential for creating lasting change in mental health care.This episode is an inspiring look at how one man's mission to lead, educate, and serve continues to evolve—and how every veteran has the power to turn pain into purpose.

In a world that often feels fragmented, uncertain, and spiritually empty, what if belief isn't just possible - but essential? Today, I'm sitting down with Ross Douthat, New York Times columnist and one of our most nuanced cultural thinkers, to explore a radical proposition: Why everyone should be religious in an age of growing skepticism. We're going beyond the debates of belief versus non-belief. This conversation dives into the mysteries at the heart of human experience - from quantum physics that suggests the universe might be more intentional than we thought, to near-death experiences that challenge everything we understand about consciousness. Douthat brings a provocative, intellectually rigorous perspective that defies easy categorization. We'll explore how ancient spiritual wisdom might hold profound answers for our hyper-individualized, technology-driven world. How can religious thinking help us navigate complexity, find meaning, and reconnect with something larger than ourselves? Expect surprises. We'll uncover scientific discoveries that point toward design, discuss supernatural experiences that defy materialist explanations, and wrestle with life's deepest questions. Whether you're a committed believer, a curious skeptic, or someone feeling spiritually lost, this episode promises to expand your understanding and offer a message of hope. We're not just talking about belief - we're reimagining what it means to be human in a mysterious universe. Ross Douthat is a columnist for The New York Times op-ed page. He is the author of Believe, The Deep Places, The Decadent Society, To Change The Church, Privilege, and Grand New Party. Before joining the Times he was a senior editor for The Atlantic. He is the film critic for National Review, and he has appeared regularly on television, including Charlie Rose, PBS Newshour, and Real Time with Bill Maher.Ross' Book:BelieveRoss' Recommendation:SeveranceSubscribe to Our Substack: Shifting CultureConnect with Joshua: jjohnson@allnations.usGo to www.shiftingculturepodcast.com to interact and donate. Every donation helps to produce more podcasts for you to enjoy.Follow on Facebook, Instagram, Twitter, Threads, Bluesky or YouTubeConsider Giving to the podcast and to the ministry that my wife and I do around the world. Just click on the support the show link belowEmail jjohnson@allnations.us, so we can get your creative project off the ground! Support the show

In episode 195, we welcome Benji Leibowitz, COO at Molecule and Co-Founder of pump.science. Benji is at the forefront of Decentralized Science (aka DeSci), a movement using blockchain to democratize research funding, unlock new discoveries, and shift power from big institutions of funders, and into the hands of scientists and the community.In this episode, we explore:How Decentralized Science (DeSci) is revolutionizing scientific research and funding The potential of IP tokens and crypto-powered science to unlock new medical breakthroughsAnd why now, amidst NIH cuts and a challenging funding environment in the US, presents a unique opportunity for DeSci to fill critical funding gaps, empower independent researchers, and accelerate scientific innovation beyond traditional institutional barriers.--Key Takeaways--

John Maytham speaks with Nazir Ismail, Head of Clinical Microbiology and Infectious Diseases at Wits University, about an extraordinary new discovery in the immune system that could revolutionize the fight against antibiotic-resistant infections. Scientists have found that the proteasome, previously known for recycling proteins, has an unexpected ability to produce bacteria-killing chemicals.See omnystudio.com/listener for privacy information.

Is “now” just an illusion? Neil deGrasse Tyson and comic co-host Paul Mecurio answer questions on the Higgs Field, dark energy, and the feasibility of Dyson spheres with astrophysicist Hakeem Oluseyi.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/hubble-trouble-with-hakeem-oluseyi/Thanks to our Patrons Omar Video, Dan Carson, Joy Jack, Christine Bryant, Andrea Andrade, mahmoud hassan, Kyal Murray, Mercedes Dominguez, Christopher Rogalski, Eric De Bruin, Telmore, Gabe Ramshaw, James Edward Humphrey, Laurel Herbert, AJ Chambers, Bill WInn, Mayson Howell, Julianne Markow, Manthan Patel, Sonya Ponds, Depression Rawr, David Leys, Garon Devine, Vishal Ayeppun, BIIZZxGaming, Kurt Clark, Max Goldberg, Beth McDaniel, Shelby Staudenmaier, Kinnick Sutton, Jane von Schilling, Joanne karl, Walter Kinslow, and Eric Johnston for supporting us this week. Subscribe to SiriusXM Podcasts+ to listen to new episodes of StarTalk Radio ad-free and a whole week early.Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

We speak with Sakana AI, who are building nature-inspired methods that could fundamentally transform how we develop AI systems.The guests include Chris Lu, a researcher who recently completed his DPhil at Oxford University under Prof. Jakob Foerster's supervision, where he focused on meta-learning and multi-agent systems. Chris is the first author of the DiscoPOP paper, which demonstrates how language models can discover and design better training algorithms. Also joining is Robert Tjarko Lange, a founding member of Sakana AI who specializes in evolutionary algorithms and large language models. Robert leads research at the intersection of evolutionary computation and foundation models, and is completing his PhD at TU Berlin on evolutionary meta-learning. The discussion also features Cong Lu, currently a Research Scientist at Google DeepMind's Open-Endedness team, who previously helped develop The AI Scientist and Intelligent Go-Explore.SPONSOR MESSAGES:***CentML offers competitive pricing for GenAI model deployment, with flexible options to suit a wide range of models, from small to large-scale deployments. Check out their super fast DeepSeek R1 hosting!https://centml.ai/pricing/Tufa AI Labs is a brand new research lab in Zurich started by Benjamin Crouzier focussed on o-series style reasoning and AGI. They are hiring a Chief Engineer and ML engineers. Events in Zurich. Goto https://tufalabs.ai/**** DiscoPOP - A framework where language models discover their own optimization algorithms* EvoLLM - Using language models as evolution strategies for optimizationThe AI Scientist - A fully automated system that conducts scientific research end-to-end* Neural Attention Memory Models (NAMMs) - Evolved memory systems that make transformers both faster and more accurateTRANSCRIPT + REFS:https://www.dropbox.com/scl/fi/gflcyvnujp8cl7zlv3v9d/Sakana.pdf?rlkey=woaoo82943170jd4yyi2he71c&dl=0Robert Tjarko Langehttps://roberttlange.com/Chris Luhttps://chrislu.page/Cong Luhttps://www.conglu.co.uk/Sakanahttps://sakana.ai/blog/TOC:1. LLMs for Algorithm Generation and Optimization [00:00:00] 1.1 LLMs generating algorithms for training other LLMs [00:04:00] 1.2 Evolutionary black-box optim using neural network loss parameterization [00:11:50] 1.3 DiscoPOP: Non-convex loss function for noisy data [00:20:45] 1.4 External entropy Injection for preventing Model collapse [00:26:25] 1.5 LLMs for black-box optimization using abstract numerical sequences2. Model Learning and Generalization [00:31:05] 2.1 Fine-tuning on teacher algorithm trajectories [00:31:30] 2.2 Transformers learning gradient descent [00:33:00] 2.3 LLM tokenization biases towards specific numbers [00:34:50] 2.4 LLMs as evolution strategies for black box optimization [00:38:05] 2.5 DiscoPOP: LLMs discovering novel optimization algorithms3. AI Agents and System Architectures [00:51:30] 3.1 ARC challenge: Induction vs. transformer approaches [00:54:35] 3.2 LangChain / modular agent components [00:57:50] 3.3 Debate improves LLM truthfulness [01:00:55] 3.4 Time limits controlling AI agent systems [01:03:00] 3.5 Gemini: Million-token context enables flatter hierarchies [01:04:05] 3.6 Agents follow own interest gradients [01:09:50] 3.7 Go-Explore algorithm: archive-based exploration [01:11:05] 3.8 Foundation models for interesting state discovery [01:13:00] 3.9 LLMs leverage prior game knowledge4. AI for Scientific Discovery and Human Alignment [01:17:45] 4.1 Encoding Alignment & Aesthetics via Reward Functions [01:20:00] 4.2 AI Scientist: Automated Open-Ended Scientific Discovery [01:24:15] 4.3 DiscoPOP: LLM for Preference Optimization Algorithms [01:28:30] 4.4 Balancing AI Knowledge with Human Understanding [01:33:55] 4.5 AI-Driven Conferences and Paper Review

Can experimenting with game design increase our chances of finding a cure for cancer? Cancer is crafty, forcing us to be just as clever in our efforts to outfox it—and we've made excellent progress, but is it time for a new play in the playbook?  In Gaming Cancer: How Building and Playing Video Games Can Accelerate Scientific Discovery (MIT Press, 2025), Jeff Yoshimi proposes a new approach to fighting an increasingly exhausting war. By putting the work of cancer research into the hands of nonspecialists, Yoshimi believes, we can accelerate the process of outgaming the disease once and for all. Gamers have already used “serious games” to discover new galaxies, digitize ancient texts, decode viruses, and solve theoretical problems in neuroscience. Cancer is a multilayered threat, and our best bet at overcoming it is via more minds working in concert. Gaming Cancer is an instruction manual for engineering games that motivate users to strain and sweat to find cancer cures. It integrates game design with research in cancer biology, data visualization techniques, and developments in cognitive science and AI while remaining sensitive to the limitations of citizen science and ethical concerns. Yoshimi sees in cutting-edge game technology the potential to educate and empower people to outwit cancer, an indirect route to richer science literacy that draws on the boundless resources of the mind. This book offers anyone invested in beating this seemingly intractable disease a concrete playbook that combines real science with creative vision in an effort to defeat the boss monster, cancer. Rudolf Thomas Inderst (*1978) enjoys video games since 1985. He received a master's degree in political science, American cultural studies as well as contemporary and recent history from Ludwig-Maximilians-University, Munich and holds two PhDs in game studies (LMU & University of Passau). Currently, he's teaching as a professor for game design at the IU International University for Applied Science, has submitted his third dissertation at the University of Vechta, holds the position as lead editor at the online journal Titel kulturmagazin for the game section, hosts the German local radio show Replay Value and is editor of the weekly game research newsletter DiGRA D-A-CH Game Studies Watchlist. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Can experimenting with game design increase our chances of finding a cure for cancer? Cancer is crafty, forcing us to be just as clever in our efforts to outfox it—and we've made excellent progress, but is it time for a new play in the playbook?  In Gaming Cancer: How Building and Playing Video Games Can Accelerate Scientific Discovery (MIT Press, 2025), Jeff Yoshimi proposes a new approach to fighting an increasingly exhausting war. By putting the work of cancer research into the hands of nonspecialists, Yoshimi believes, we can accelerate the process of outgaming the disease once and for all. Gamers have already used “serious games” to discover new galaxies, digitize ancient texts, decode viruses, and solve theoretical problems in neuroscience. Cancer is a multilayered threat, and our best bet at overcoming it is via more minds working in concert. Gaming Cancer is an instruction manual for engineering games that motivate users to strain and sweat to find cancer cures. It integrates game design with research in cancer biology, data visualization techniques, and developments in cognitive science and AI while remaining sensitive to the limitations of citizen science and ethical concerns. Yoshimi sees in cutting-edge game technology the potential to educate and empower people to outwit cancer, an indirect route to richer science literacy that draws on the boundless resources of the mind. This book offers anyone invested in beating this seemingly intractable disease a concrete playbook that combines real science with creative vision in an effort to defeat the boss monster, cancer. Rudolf Thomas Inderst (*1978) enjoys video games since 1985. He received a master's degree in political science, American cultural studies as well as contemporary and recent history from Ludwig-Maximilians-University, Munich and holds two PhDs in game studies (LMU & University of Passau). Currently, he's teaching as a professor for game design at the IU International University for Applied Science, has submitted his third dissertation at the University of Vechta, holds the position as lead editor at the online journal Titel kulturmagazin for the game section, hosts the German local radio show Replay Value and is editor of the weekly game research newsletter DiGRA D-A-CH Game Studies Watchlist. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science-technology-and-society

Is fusion the future of energy and space travel? Neil deGrasse Tyson and co-host Paul Mecurio explore the cutting-edge science of plasma physics and fusion energy with Fatima Ebrahimi, a physicist at Princeton Plasma Physics Lab.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/the-future-of-fusion-energy-with-fatima-ebrahimi/Thanks to our Patrons Christopher Salins, Alan Zismann, Paul Johansson, Aaron Brodsky, Debbie Fleming, Thayna Scarpetto, Kris, Jacob Mayfield, Danny Desmond, Tim Ellis, The Running Knitter, Kevin Collins, Mario Funes, Wendi McCall, Paula Patzova, derek lindstrom, Dave Jankus, Mercy Robinson, Linda Safarli, Hexeris, Julian Rassolov, Templex, Joseph, Adrian Aguilar, Nathan Colbert, Andoni Cardenas Huerta, Terrance B, William Strawbridge, Gabriel Torres, enrico janssens, Jonathan Winterrowd, Valentin Scherrer. For Chuck, just call me Val, Ozzie Springer, and Moon Light for supporting us this week. Subscribe to SiriusXM Podcasts+ to listen to new episodes of StarTalk Radio ad-free and a whole week early.Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

Welcome to Stanford Engineering's The Future of Everything, the podcast that delves into groundbreaking research and innovations that are shaping the world and inventing the future. The University has a long history of doing work to positively impact the world and it's a joy to share about the people who are doing this work, what motivates them, and how their work is creating a better future for everybody. Join us every Friday for new episodes featuring insightful conversations with Stanford faculty and to discover how Stanford's research is transforming tomorrow's world. Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

In this Convo of Flanigan's Eco-Logic, Ted speaks with Dr. Jennifer Bousselot, Assistant Professor at Colorado State University (CSU) in the Department of Horticulture and Landscape Architecture. Jennifer is exploring new and innovative ways to improve the productivity and aesthetics of modern urban spaces by harnessing the twin powers of the sun and plantlife. She specializes and is a leading expert in green roof research on native species evaluations, plant drought tolerance, integration with solar panels, and rooftop agrivoltaics. Jennifer shares a bit about her background, growing up on a 360-acre farm in Iowa, and was the youngest of 8 kids. She and her twin sister worked on the farm, and carried their deep farming roots into their careers. She earned her undergraduate and master's degrees at Iowa State University, and after a stint as a horticulture agent for the CSU Extension office in Douglas County, she followed her passion and pursued a doctorate of science in horticulture at CSU.Jennifer shares details on her green roofs project for her doctoral thesis, highlighting how she came upon rooftop agrovoltaics as a happy accident, finding there was a great synergy between the plants and solar panels; the plants grew better, and the solar performed better because of the plants' cooling effect. With a roster of graduate students and researchers, her team is pushing the boundaries of horticultural science with numerous pieces of published research and scientific discovery every year. She goes into the history of green roofs, and discusses her research on rooftop agrivoltaics and its benefits, including enhanced food production and security, improving clean energy pathways, and exploring sustainability integrations. 

How much more physics is out there to be discovered? Neil deGrasse Tyson sits down with physicist, professor, and rockstar Brian Cox, to discuss everything from the Higgs boson, life beyond our planet, and the fundamental forces that guide our universe.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/our-world-of-particles-with-brian-cox/Thanks to our Patrons Anthony Sclafani, Alejandro Arriola-Flores, Brian Christensen, Allen Baker, Atlanta Gamer, Nigel Gandy, Gene, Lisa Mettler, Daniel Johansson, Sunny Malhotra, Omar Marcelino, yoyodave, Mo TheRain, William Wilson, ChrissyK, David, Prabakar Venkataraman, PiaThanos22, BlackPiano, Radak Bence, Obaid Mohammadi, the1eagleman1, Scott Openlander, Brandon Micucci, Anastasios Kotoros, Thomas Ha, Phillip Thompson, Bojemo, Kenan Brooks, jmamblat@duck.com, TartarXO, Trinnie Schley, Davidson Zetrenne, and William Kramer for supporting us this week. Subscribe to SiriusXM Podcasts+ on Apple Podcasts to listen to new episodes ad-free and a whole week early.

What if the tiniest materials in the universe could save lives, fight diseases, and reshape our future?Today, we're uncovering the answers with Dr. Antonios Kelarakis. Join us for: The power of nanomaterials: Discover the science behind these tiny but mighty materials and their revolutionary potential. Exciting real-world applications: Learn how ultra-bright carbon dots are transforming medical treatments and how graphene coatings are combating harmful microbes. The role of AI in research: See how artificial intelligence is reshaping the discovery and development of groundbreaking materials. The big question: Can science truly save the next generation? This episode is packed with cutting-edge insights and real-world applications that will leave you inspired about the future of science and technology. Episode Chapters To help you navigate this episode, here are the chapter timestamps: 04:31 – Navigating the Academic Landscape 11:29 – Materials Alchemy: The Science Behind Innovation 16:59 – The Smart Revolution: Nanomaterials in Action 23:23 – Collaboration: The Heart of Scientific Discovery 27:21 – Theragnostics: The Role of Carbon Dots 29:52 – Graphene and Antimicrobial Coatings 33:33 – AI's Impact on Research and Academia 37:32 – Challenges and Opportunities in Nanomaterials 40:29 – Can Science Save the Next Generation?

Imagine a future in which Band-Aids talk to your cells, pacemakers are powered by light and your gut microbiome gets a tune-up—all thanks to tiny bioelectric devices. Sounds like sci-fi, right? Think again. Prof. Bozhi Tian of the University of Chicago is on the frontier of bioelectronics, building living machines that can heal, enhance and maybe even transform what it means to be human. In this episode, he explains his research lab's work and explores the thrilling, strange and sometimes unsettling world in which biology meets technology.

Stephen Dubner, live on stage, mixes it up with outbound mayor London Breed, and asks economists whether A.I. can be “human-centered” and if Tang is a gateway drug. SOURCES:London Breed, former mayor of San Francisco.Erik Brynjolfsson, professor of economics at Stanford UniversityKoleman Strumpf, professor of economics at Wake Forest University RESOURCES:"SF crime rate at lowest point in more than 20 years, mayor says," by George Kelly (The San Francisco Standard, 2025)"How the Trump Whale and Prediction Markets Beat the Pollsters in 2024," by Niall Ferguson and Manny Rincon-Cruz (Wall Street Journal, 2024)"Artificial Intelligence, Scientific Discovery, and Product Innovation," by Aidan Toner-Rodgers (MIT Department of Economics, 2024) EXTRAS:"Why Are Cities (Still) So Expensive?" by Freakonomics Radio (2020)

The complete archive of Subversive episodes, including exclusive episodes and my writing, is available on Substack.For a bit less, you can also subscribe to the podcast sans writing on Patreon. This is how the show is financed and grows, so I appreciate every contribution!Please subscribe at:⁠⁠https://www.alexkaschuta.com/⁠⁠⁠⁠https://www.patreon.com/aksubversive⁠Our chat explores the evolution of Human Biodiversity (HBD) discourse and the challenges of understanding complex data related to cognitive stratification and social mobility. We also discuss the impact of genetic technologies on future societal structures and the cultural perspectives surrounding fertility technologies, particularly in Eastern Europe. We also discuss the complexities of the economic viability of modern society, the challenges of immigration and integration, the rise of woke culture, the fragility of liberalism, the dynamics of gender, financial status, and relationships, particularly in the context of the baby boom and modern dating challenges. Our conversation also touches on parenting, emphasizing the limited impact of parenting styles on child development and the importance of understanding the realities of modern relationships. JayMan is a pseudonymous blogger: unz.com/author/jayman/ and can be found on X.com @JayMan471 Chapters 00:00 The Evolution of Human Biodiversity Discourse 04:00 The Impact of HBD on Society 08:01 Understanding Averages and Cognitive Stratification 09:50 Social Mobility and Assortative Mating 13:58 The Future of Genetic Technologies 17:51 Cultural Perspectives on Fertility Technologies 21:54 The Role of Scientific Discovery in Progress 29:02 The Economic Viability of Society 30:42 Immigration and Integration Challenges 32:52 Experiencing Dystopia: A Personal Account 36:43 The Rise of Woke Culture and Backlash 40:20 The Right's Response to Woke Culture 44:57 The Future of Immigration Policy 49:50 Global Voices and Cultural Shifts

Look at what Santa dropped when he came down the chimney last night. A bunch of valuable ThisISResearch Best paper Awards! As we do at the end of every year, we look back at the finest information systems scholarship our field has produced this year, and we pick some of our favorite papers that we want to give an award too. Like in previous years, we recognize three different kinds of best papers – a paper that is innovative in its use of research methods, a paper that is a fine example of elegant scholarship, and a paper that is trailblazing in the sense that it starts new conversations in our field. References Pujol Priego, L., & Wareham, J. (2023). From Bits to Atoms: White Rabbit at CERN. MIS Quarterly, 47(2), 639-668. Recker, J., Zeiss, R., & Mueller, M. (2024). iRepair or I Repair? A Dialectical Process Analysis of Control Enactment on the iPhone Repair Aftermarket. MIS Quarterly, 48(1), 321-346. Seidel, S., Frick, C. J., & vom Brocke, J. (2025). Regulating Emerging Technologies: Prospective Sensemaking through Abstraction and Elaboration. MIS Quarterly, 49, . Abbasi, A., Somanchi, S., & Kelley, K. (2025). The Critical Challenge of using Large-scale Digital Experiment Platforms for Scientific Discovery. MIS Quarterly, 49, . Lindberg, A., Schecter, A., Berente, N., Hennel, P., & Lyytinen, K. (2024). The Entrainment of Task Allocation and Release Cycles in Open Source Software Development. MIS Quarterly, 48(1), 67-94. Kitchens, B., Claggett, J. L., & Abbasi, A. (2024). Timely, Granular, and Actionable: Designing a Social Listening Platform for Public Health 3.0. MIS Quarterly, 48(3), 899-930. Chen, Z., & Chan, J. (2024). Large Language Model in Creative Work: The Role of Collaboration Modality and User Expertise. Management Science, 70(12), 9101-9117. Matherly, T., & Greenwood, B. N. (2024). No News is Bad News: The Internet, Corruption, and the Decline of the Fourth Estate. MIS Quarterly, 48(2), 699-714. Morse, L., Teodorescu, M., Awwad, Y., & Kane, G. C. (2022). Do the Ends Justify the Means? Variation in the Distributive and Procedural Fairness of Machine Learning Algorithms. Journal of Business Ethics, 181(4), 1083-1095. Hansen, S., Berente, N., & Lyytinen, K. (2009). Wikipedia, Critical Social Theory, and the Possibility of Rational Discourse. The Information Society, 25(1), 38-59. Habermas, J. (1984). Theory of Communicative Action, Volume 1: Reason and the Rationalization of Society. Heinemann.   

In this episode of The Cognitive Revolution, Nathan interviews Andrew White, Professor of Chemical Engineering at the University of Rochester and Head of Science at Future House. We explore groundbreaking AI systems for scientific discovery, including PaperQA and Aviary, and discuss how large language models are transforming research. Join us for an insightful conversation about the intersection of AI and scientific advancement with this pioneering researcher in his first-ever podcast appearance. Check out Future House: https://www.futurehouse.org Help shape our show by taking our quick listener survey at https://bit.ly/TurpentinePulse SPONSORS: Oracle Cloud Infrastructure (OCI): Oracle's next-generation cloud platform delivers blazing-fast AI and ML performance with 50% less for compute and 80% less for outbound networking compared to other cloud providers13. OCI powers industry leaders with secure infrastructure and application development capabilities. New U.S. customers can get their cloud bill cut in half by switching to OCI before December 31, 2024 at https://oracle.com/cognitive SelectQuote: Finding the right life insurance shouldn't be another task you put off. SelectQuote compares top-rated policies to get you the best coverage at the right price. Even in our AI-driven world, protecting your family's future remains essential. Get your personalized quote at https://selectquote.com/cognitive Shopify: Shopify is the world's leading e-commerce platform, offering a market-leading checkout system and exclusive AI apps like Quikly. Nobody does selling better than Shopify. Get a $1 per month trial at https://shopify.com/cognitive CHAPTERS: (00:00:00) Teaser (00:01:13) About the Episode (00:04:37) Andrew White's Journey (00:10:23) GPT-4 Red Team (00:15:33) GPT-4 & Chemistry (00:17:54) Sponsors: Oracle Cloud Infrastructure (OCI) | SelectQuote (00:20:19) Biology vs Physics (00:23:14) Conceptual Dark Matter (00:26:27) Future House Intro (00:30:42) Semi-Autonomous AI (00:35:39) Sponsors: Shopify (00:37:00) Lab Automation (00:39:46) In Silico Experiments (00:45:22) Cost of Experiments (00:51:30) Multi-Omic Models (00:54:54) Scale and Grokking (01:00:53) Future House Projects (01:10:42) Paper QA Insights (01:16:28) Generalizing to Other Domains (01:17:57) Using Figures Effectively (01:22:01) Need for Specialized Tools (01:24:23) Paper QA Cost & Latency (01:27:37) Aviary: Agents & Environments (01:31:42) Black Box Gradient Estimation (01:36:14) Open vs Closed Models (01:37:52) Improvement with Training (01:40:00) Runtime Choice & Q-Learning (01:43:43) Narrow vs General AI (01:48:22) Future Directions & Needs (01:53:22) Future House: What's Next? (01:55:32) Outro SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://www.linkedin.com/in/nathanlabenz/ Youtube: https://www.youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk

Episode: 1273 Some surprises in the 1852 Annual of Scientific Discovery.  Today, an old book takes stock of science and art in 1852.

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