Podcasts about Mitosis

This is the last episode before the Season 3 Finale featuring Kent Chungus! In this episode Brad the Impaler, Wesley Weaseltits, Phil Downerpants, and the Research Department are joined by special guest Mitosis!

This episode explores the critical role of tryptophan, an aromatic amino acid, in forming tubulin—the key protein building microtubules, which act as cellular "train tracks" for structure and movement. We delve into how microtubules drive mitosis, the process of cell division essential for growth and repair, and discuss tryptophan's unique biochemical significance, including its single codon (UGG) and contributions to DNA methylation.We connect these cellular mechanisms to Autism, examining how microtubule disruptions may affect neuron proliferation and migration during prenatal development, potentially leading to sensory processing issues and altered connectivity. The episode highlights the intricate dance of cells in neural tube formation and emphasizes the need for deeper research into these upstream processes to uncover Autism's developmental roots.YT video of tryptophan and microtubules https://youtu.be/AY6GmS_AePk?si=K_ZTy5RjLGkm1hGdInner Cell Life video https://youtu.be/RrS2uROUjK4?si=DCHs927yteOZ00dWSee Stuart Hameroff, Martin Picard, Michael Levin, Jack Kruseuse "autism" for $25 off athttps://buy.daylightcomputer.com/RYAN03139use "autism" for 10% discount athttps://getchroma.co/?ref=autism00:00 Daylight Computer Company, use "autism" for $25 discount04:22 tryptophan, aromatic amino acid, microtubules, mitosis; human biology, autism04:44 tryptophan, UGG codon, methionine, SAM, MTHFR, folate, DNA methylation; upstream biology, RNA, DNA06:04 microtubules, train tracks, mitosis, cell division, spindle, DNA separation; skin repair06:55 tryptophan, tubulin, microtubules, mitosis, intracellular transport, cell shape; Autism research, upstream processes9:25 Chroma Light Devices- Lights Designed for Humans, use "autism" for 10% discount12:27 tryptophan fluorescence, mitosis, prophase, prometaphase, metaphase, anaphase, telophase, cytokinesis; microtubules, chromosome movement, cell division, tissue repair15:58 mitosis, neural tube, embryonic development, neuron proliferation, migration; Autism, brain size, connectivity20:33 sensory processing, hyperconnectivity, synaptic pruning, microtubules; Autism, sensory sensitivities, cortical connections25:06 excitation-inhibition imbalance, microtubules, environmental toxins, light exposure, fertilization, blastocyst; Autism, prenatal development, cell polarity31:09 microtubules, neural tube, gastrulation, neurogenesis, synaptogenesis, ectoderm, mesoderm, endoderm; Autism, cell migration,37:18 outro, reviewsX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

(00:47) Wie sagt man «Klimakleber» auf Rätoromanisch? Oder «Bierdose»? Dafür hat die Hüterin der romanischen Sprache und Hauslinguistin von RTR ein Wort gebildet. Weitere Themen: (10:54) «Aarauer Demokratietage»: Wie können Demokratien vor Kriegen Schützen? Ein Gespräch mit Laurent Goetschel. (15:32) «Wie ein Mann nichts tat und so die Welt rettete» von Lukas Maisel ist ein packender Roman, hätte aber das Potenzial zu mehr geboten. (20:15) Wanda Dufners «Bauchlandung» ist eine unterhaltsame Graphic Novel über die Herausforderungen einer Teenagerschwangerschaft. (24:22) «MITOSIS: an LSD opera»: Ein Musiktheaterstück über das Sterben und welche Rolle psychedelische Drogen dabei spielen können. (28:31) Fasnachtsscherz wird Justizfall – Ausgerechnet in Payerne, wo 1942 Schweizer Nazis einen Juden umbrachten.

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]

Have you wondered why you're not getting the six figure airdrops like you did from back in DeFi Summer of 2020? Jake Kim of Mitosis—and former Luna Anchor dev—spills the tea.#blockchaintech #technews #web3news #interchainfm #cryptocurrency #cryptopodcasts #mitosis

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“Seth Meyers And the Cauldron of Doom” OMG— YOU have a cauldron of doom?! I have a cauldron of doom!!! DO NOT SHAKE THIS SNOWGLOBE. I had been avoiding Rockefeller plaza for months as it was, without the sometimes accidental ending up there anyway, and I thought not once but twice or three times about changing into my regular pants so that the deep pockets could hold my keys and passports sans wallet— or a purse and considered taking a notebook as well; on the list of prohibited items were backpacks and large bags, and though the dress code seemed to be null in void at all, I was happy to be able to wear my hat at least— and almost prepared to be dogged out, the last min it e change into my harem pants would probably be the comfortable choice; looking intentionally dressed down as a statement—a broad statement that I wasn't looking to be noticed at all, or trying to be noticed. The guest for the show was nearly an EGOT winner, probably younger, and definitely skinner and more beautiful than I was; a black woman, but a British woman, and it would be almost entirely impossible to think that besides Whoopi Goldberg, an American black woman would strive to win such a thing as an EGOT herself. Still, I was looking for a cure to the writer's block and crippling depression that I had been in, however—knowing who the president of Peacock was, and after the elections at all's though I knew NBC to be left-leaning— I didn't feel at all as if I would ever belong on the stage, and was quite happily taking my place as simply a fan…and audience member, though ready to creep back into obscurity, and probably more likely than not with a pint of Ben and Jerry's after the show. I had gone to see Drew Barrymore sand makeup, and would do the same, but only as a proclamation that I had read Tina Fey's book nearly religiously now rounding three times, and I almost wish I had an oversized black t-shirt which read “hot water heater” to accompany my lax look and blonde hair—a testament to her correctness standing, as the grossities of tinder loved “the blonde”, almost as if, without the hair I would be ugly, and just as much in the same breath, unworthy of such status anyway. But more than anything, I just wanted to be able to write again, at least for my own sake, and certainly not for anyone else's. I was still in hiatus, for the better, and had not completely recovered from the unbearable racism and parallel of doom the election had tossed me into with trajectory—in this world—supposedly “fascist”. I was comfortable enough in the jeans, but had nowhere to put my phone. I was ready to be dogged out and shown what a real a list celebrity looked like, and why I simply wasn't one. I left the house with a sink full of dishes, an unmade bed, and a pile of laundry unfolded—a pile of books in boxes I had collected for my son but would cost too much to send—almost as a testament to his sick I had been since the election. In this world, I was just another poor black fat single mother— a dead beat living in poverty. In trump's world, I was an ugly, poor nothing. Everywhere I had gone about the past week, the rich seemed richer and the poor poorer, the whites whiter and the blacks blacker, good gone and evil fleeting, with the return of the motorcycles and pieces of me dying, simply giving up. I planned my return to the workforce, and the eventual fortitude of my freedom; the wealthy had become more arrogant, and the rest of us more distraught. What was I going to rocketfeller plaza for, anyway? The news. My apartment was disgusting, but at least I had been to the gym—I had run the full mile and lifted and pulled, all with the gym to myself. My harem pants still felt even better, and for the first time in me months I ventured into the world in only one waist trainer. Be prepared to be [lost in a revolving door Be cool to the two dudes in blue suits goddamnit I never know where I'm going in this bitch. I can never breath in this bitch and I don't know why. How do you get lost at the rock? Like this: [Infinitely Lost at Rockafeller Plaza] This is why I avoid this place like the plague. Maybe I'm the plague. First of all, there's no track on the floor upstairs. (I've never been upstairs.) It's just store after store of ways to spend money. This is my only pair of clean socks. No shit, this is the reason practicing your mantras on the train becomes dangerous. DANGEROUS. Somewhere in the frenzy, I remember this. Frequency, however, Not yet partial to my own inner self, and empty in the array of superstardom, I become nothing, Only a spectator of celebrity— And now, suddenly. 8 remember this day Why? Suddenly, now, in the Is moment. Where I always have been, waiting for myself— I avoid Rockerfeller plaza at all costs. Why. I heard a grimlin lives here. Now is the time for Skrillex! I would really love you forever if you didn't. Que the Arc! Oh boy, this writer's block is a doozy. The only reason I had even bothered was because it was as if I had been summoned, as if something had clocked in my sense memory where, all of a sudden, looking at an unrelated picture of some kid on Tinee, with his hands covering his mouth the way that Stefon always did, made me immidiately stop whatever I was doing—probably eating tacos or pancakes, insurmountably out of bounds— and pausing the comedian I was watching instead, just to watch Stefon, and in the way that I remembered it all, it made me laugh. Although now, I knew exactly what he was talking about by the avant-grade and strangely abysmal club scene not just of the time, but of any time in New York City— and, somehow summoning a laugh even in the darkness that had been my own distraught and depression in the previous weeks, something of a belly roll laugh might have triggered something in the alrgorithm to send last minute tickets to my email in almost that exact moment. Are they going to tell me to take off my hat?! There was no dress code, They had better not tell me to take off my motherfucking hat. I won't do it. Fuck Seth Meyers . I'm not taking off my hat for Seth Meyers. Oh yeah. That's why I'm here. I found it hard to say that I was there for such a thing; I— I turned off my peripheral vision and hyperfocus. I didn't know there would be music. Goddammit. I had deleted Shazam filming for I love New York, an all but abandoned project—the writer's block had been too real, and now the real rest had come—would I laugh at anything in show show when in reality I wanted to cry? The way the lights kept going up and down as if it were intermission only slightly distracted from the fact that I had never seen a page in real life. THEY EXIST . I had never seen an actual NBC PAGE. GODDAMMIT GET THIS BLUE SUIT LOAFER WEARING MOTHERFUCKER OUT OF MY PERIPHERAL BEFORE I LOSE IT. Shoot a midget at her. What. Just do it. Don't do that. What Don't put the midget in the cannon. What! Thays's what he's here for! I'm a stunt double! This is a stunt. That's a horrible joke. That's not a joke. SHAZAM. WTF IS THIS. Some top 40 bullshit. Good, get it ( I'm never going to have any other l exposure to top 40, ever in my life. ) Congratulations, you've made the A list What?! NO FAIR. What. What does that mean. It means I can't do shit and mandatory attendance to everything. What is everything “Everythin—g.” Man, fuck this. Alright At this moment, I realize I must be some sort of autistic. Let's get this over with… I let the sound of my own mix blare in my ears to drown out the sound of whatever pop singer was on over the loud speakers; I didn't realize there would be music, and I hoped the flutter was good l. Maybe it was the lights, or whatever, but— SUNNI BLU what in the fuck dimention is this . It's the same dimension, you're just drunk. Ah. Now what? I was as uncomfortable as ever, there was a track on the higher level, but it didn't matter, the cattle call was contained inside of velvet ropes— black ones, unlike the typical red ones, and it was at this point I realized that not only had I never seen actual NBC pages— Yo, their skirts are kinda short… RIGHT. I THOUGHT THE PAGES WERE THE PARAGON OF SANCTITY! No, those are, um… Nvm. Maybe the ugly shoes distract from the shortness of their skirts on the general basis. Oh come on, nobody gives a fuck how ugly your shoes are if your skirt is that short! These are facts, Liz. No, I'm serious what dimention is this. I already told you. I had to ask for directions three times just get here. THIS IS MY LEVEL. why is your level on acid. Cause. This is—just— Where I'm at. CUT TO: Jimmy Fallon after Mardi Gras's. Come on that's not fair! {Enter The Multiverse} What exactly isn't fair?! He's in all the scenes. Well, how else are you going to explain a time traveling helicopter?! Got him. THERES MY INVISIBLE MOTORCYCLE. I'm not going to pa— Goddamn it. I'm not going to p— It actually hurt not to write and just stand there; but I still didn't feel like myself—or sound like myself—or look like myself; I was playing a character, I just didnt know who. As I moved forward in line, the music began to fade away behind me and into the nothingness that was whatever was behind, in front of, and all around me. I hated cattle calls, but after all, I was still just a fan and as the world began to fold into chaos, I realized that my pants were falling off of me, though I had been feeling fat, and walking, and running, and cycling, and protein shaking—the only thing that had gained any extra weight was my ass, which was exactly what I was intending on hiding with my same old usual harems. My blonde hair made it so that I stuck out like a sore thumb, but that didn't matter, I was a walking statement piece and almost in a fit of tears just thinking about my own status; the NBC pages probably all had crazy incredible accolades and numerous degrees and achievements—what was I, if anything at all— ? I had put the candles out, but had I left the stove on? Did I really unplug the nail dryer and leave the stove on? I had almost washed all of the dishes, but stopped just short of right on time to leave; my producer brain was on fire and wanted more pancakes, but however hard I tried I could not find where I had placed my EBT card; probably for the better—celebrities didn't carry EBT cards, and even my awkward general being thrown off by the doorman or security— —whichever I wasn't sure— standing outside of the roller rink— probably ice this time of year, by the looks of the Zamboni in the foreground of it… ‘Don't stop writing, no matter what. ‘ Dammit, dammit dammit— That seems inappropriate. I told you to get this motherfucker out of my peripheral before something— Nevermind, don't write that. [redacted] (But imma remember this shit cause it's heavy.) A remarkable and accidental tableau, My feet flat to the floor, as my ankles bare, This is my only pair of hole-less socks. I feel so much better with my back against the wall and Listening to mau5 and, Not giving a fuck about the music playing Or the people watching But keeping it for later Forgetting how to codeswitch, Just an ever so limited existence Trying not to stick out like a sore thumb in the wrong world It's a long way up, But even longer way down, And in all the demoralizing humiliation and emasculation, I realize I'm no man at all, No man at all I realize I'm no man at all, No man at all, No mana I realized my son's Lego Lamborghini should be waiting for me as I returned to my apartment in Brooklyn probably starting but pretending not to care; I winced at everything— this was a dangerous disaster, to even be in the building at all and edging closer to death were the secrets I kept that were not only secrets, but non existences. Nothing in nothing and nothing— Oh shit, is the suffering done? This is the end of the End of the end It's the Beginning of the end It's the end of the beginning This will be the end Of the end Of the end, This will be the end of the end Of the end Of the end Of the beginning Of the end Of the beginning of the end. This will be the end Of the end Of the end Of the beginning of the beginning Of the end of the end Of the beginning Of the end This will be the end Of the beginning Of the beginning Of the beginning Of the end Of the end Of the end This will be the end Of the beginning of the beginning This will be the beginning of the beginning of the beginning This will be the beginning, The beginning of the end This will be the end of the end of the end This will be the end of the end of the end This will be the end (This will be the end) Of the beginning This will be the beginning The beginning of the beginning Of the end My friends. LET US COMMECE! All of it, this is recorded history, Smoke and mirrors, here portions and pardons This is probably why can't breathe at the rock Was I here last time; I choked last time I wrote nothing remarkable at all (Nothing remarkable at all.) I love getting lost at the rock Okay, this is the host— This is the host of the show (I think I lost my lunch before.) I was at a show, I never woke up, Okay; This is the host This is the host (This is the host) This is the host. Cue the Nirvana; Curtains go up, I don't want to see the show, I just want to host it. I don't want to get lost no more On the way to the rock Or the store Cause only one train goes there I wanna climb the straits to the top Get lost at the rock, Guess this isn't he host huh This is the lost god, That was a long walk The top of the rock off is a long jump And I'm still in talks how's every morning Someone told me not to ignore you So, this is the host, huh. Someone told me, go hard or go home (Almost time tknkove) Parenthesises, please and—Parenthetical, hypotheticals and paleontology's, Please, I need a mixologist (And anthologist) Please slow down to peace, Mr poltergeist, Please Mr poltergeist The ghost of Mr giest I'm doing a hiest Please, slow down mister poltergeist, Please for the peace Mr. Poltergeist, Or what have you? How old are you, 40. I'm the whole medium and still, Nice to meat you sir. A house made of mediums I hope that shock, And I hop to the rock there's still something in it A pogo stick Or a poltergeist Slow down, poltergeist. Terrible timing, Victoria Beckham and monsuier, Please Mr, I mean it no more— If I'm Mr ooltergieat (A policeman and polgergeist) Please, sir, no jokes. All sandwhich, no buns and pastrmi, And all the God, I'm going cold, I'm going ghost again And a the god, on all the rocks, I'm going old, I'm going cold again; On all the God on all the rocks, I'm going God, I'm going old again Hold on again, mi got a song again? I'm just a serviceman WATCH OUT FOR THE DOORMAN. MORE FUEL. So all the Rockerfeller plazas on all the earths aim alll yhr parallel dimensions can actually communicate with each other RADIO CITY BABBBBBBBYYYYYYY! OH GOD. WHAT ARE YOU DOING HERE Did you get his dog's name!? I think so. Good. [meniacal rubbing of hands] good. Cue the nirvana. Cue the m— Mitosis. The migos. Nah, I can't catch the flow. There it is. [the flow is a literal] Something medicinal in this meniacal, is this I spy a specscle, monocle— monopoly, Time to go, it's the devil at my left; Time for the fight against darkness, And it all is, Cause this is the ark, Noah This is the arc, God. This is apartheid and apart from that. You're fired. What. You heard me. But—I'm Seth Meyers. That's debatable. I am! I'm Seth Meyers. If you say so. This is nonsense. It's not nonsense. It is nonsense. And it's also impossible; cause this is my show. It's my show, I'M SETH MEYERS. Debatable, Not debatable. I'm ME. THAT'S ME. Debatable. I can't even hear the words, But the bass is so fire, I summon Shazam! …I want a ham sandwhich. Oh good! He's alive. Ham. Sandwhich. What the fuck happened buddy?! Where were you man?! —Zoolander. What. disleylandhamsandwhich. Get him a sandwhich!!!!! YO QUIERO CUBANO. Here's your sandwhich. CUBANO. Remember what you look like Who you are What your place is What you weigh, And Check your status Remember how still started What your mark is And what happened to your wallet; Did you leave the stove on Do you put the show on; Did you miss your mark Your mom was hotter Please remember the circumstances In which you—- [BLACKOUT] After several days gone completely missing, Jimmy Fallon is found under the craft services table sleeping peacefully. The apparatus I entered in with Is not adjusted to this condition The biometrics are non concurrent; {enter the multiverse} I felt tragic. By the time I got back to my apartment, my ribcage was showing again—although I had only been wearing one waist trainer, it was the skimpy one, and it was already wearing, it was after all eight dollars. Really and once and for all, something had come over me at Rockerfeller plaza that I didn't understand. I was more awkward and nervous than usual, and sure that I should have eaten, but couldn't —even after a long gym session, there was no time for food before the show, and I had no stomach for it. I chose to as much as I could ignore the code switching, and the more I picked it up, the further my mind began to drift. —a door slammed. My documents were probably compromised, and my phone hacked which I might have guessed, but continuing the thought I had often wondered how or why anything could have possibly known what I had written, or how—or how anyone would know what I had written, or of the things I had written, and most importantly of all—what did I write?! Most of the previous months' entries into the festival project were a blank, and the time I had spent considerably enough sifting through whatever masked man acting in part of Fallon, whoever he really was had been turbulent, as if I had been disfigured to be brainwashed into half a mind—then, slowly peeking back the layers of such a chaotic artifact of time and this, Seth Meyers, to whom now I had become a loyal fan, an actual fan—and had noticed something ingenuously crafted here. A genuine and talented, very kind and gifted man, who was not in any sense miserable or in peril. Peril, so to speak, as I remembered the almost villainous approach that the decent into madness had accompanied this Fallon and his mask, and besides this was the assumption that Seth Meyers, though professionally trained as such, seemed happy. Fallon did not. We had all learned to craft masks in order to protect our inner selves—however, with such a veil lifted as the partitioned screen of all does, this spoke to me with numerous volumes and sometimes even screamed, with the ethics of no worse a gentleman than some surgeon soldier or sailor and no more a nobleman than a king or god itself; I had not been Shocked and all but murmured even to just the slightest gawk of just an awkward cry, a muster of some shallow disaster which had called me to all of them— to whom I had loved and yet somehow not known, at least being here—and here I was, slightly convulsed, bearing no armor and gripping at the fortitude of death's barriers; On wheels with no bearings plummeted towards a forged death of sorts, by my own hands but also at the hands of others, the forgery calling from the halls of a place I had known as once my own fortress; but was no more. I belonged and now, almost with gratitude, to the eye of all gods, and all things that moved. No cherished nature, perhaps, was this into my own eye, but of disgust for what I had not yet accomplished, and still might never— I was a skull and crossbones with no love, and nothing known at all besides my own. —Tales of a superstar DJ “16 Songs” I got it. What's that. The thing that sets Seth Meyers apart from the other hosts. What is it? Seth Meyers is not a host—he's an anchor. Goddammit, you're right . I know I'm right. GODDAMIT. It just took me this long to figure it out . Great. Now how long's it gonna get you to take this thing fixed. Possibly forever. Entaer The Multiverse} [The Festival Project.™] COPYRIGHT © THE FESTIVAL PROJECT 2024 ALL RIGHTS RESERVED. ©

“Seth Meyers And the Cauldron of Doom” OMG— YOU have a cauldron of doom?! I have a cauldron of doom!!! DO NOT SHAKE THIS SNOWGLOBE. I had been avoiding Rockefeller plaza for months as it was, without the sometimes accidental ending up there anyway, and I thought not once but twice or three times about changing into my regular pants so that the deep pockets could hold my keys and passports sans wallet— or a purse and considered taking a notebook as well; on the list of prohibited items were backpacks and large bags, and though the dress code seemed to be null in void at all, I was happy to be able to wear my hat at least— and almost prepared to be dogged out, the last min it e change into my harem pants would probably be the comfortable choice; looking intentionally dressed down as a statement—a broad statement that I wasn't looking to be noticed at all, or trying to be noticed. The guest for the show was nearly an EGOT winner, probably younger, and definitely skinner and more beautiful than I was; a black woman, but a British woman, and it would be almost entirely impossible to think that besides Whoopi Goldberg, an American black woman would strive to win such a thing as an EGOT herself. Still, I was looking for a cure to the writer's block and crippling depression that I had been in, however—knowing who the president of Peacock was, and after the elections at all's though I knew NBC to be left-leaning— I didn't feel at all as if I would ever belong on the stage, and was quite happily taking my place as simply a fan…and audience member, though ready to creep back into obscurity, and probably more likely than not with a pint of Ben and Jerry's after the show. I had gone to see Drew Barrymore sand makeup, and would do the same, but only as a proclamation that I had read Tina Fey's book nearly religiously now rounding three times, and I almost wish I had an oversized black t-shirt which read “hot water heater” to accompany my lax look and blonde hair—a testament to her correctness standing, as the grossities of tinder loved “the blonde”, almost as if, without the hair I would be ugly, and just as much in the same breath, unworthy of such status anyway. But more than anything, I just wanted to be able to write again, at least for my own sake, and certainly not for anyone else's. I was still in hiatus, for the better, and had not completely recovered from the unbearable racism and parallel of doom the election had tossed me into with trajectory—in this world—supposedly “fascist”. I was comfortable enough in the jeans, but had nowhere to put my phone. I was ready to be dogged out and shown what a real a list celebrity looked like, and why I simply wasn't one. I left the house with a sink full of dishes, an unmade bed, and a pile of laundry unfolded—a pile of books in boxes I had collected for my son but would cost too much to send—almost as a testament to his sick I had been since the election. In this world, I was just another poor black fat single mother— a dead beat living in poverty. In trump's world, I was an ugly, poor nothing. Everywhere I had gone about the past week, the rich seemed richer and the poor poorer, the whites whiter and the blacks blacker, good gone and evil fleeting, with the return of the motorcycles and pieces of me dying, simply giving up. I planned my return to the workforce, and the eventual fortitude of my freedom; the wealthy had become more arrogant, and the rest of us more distraught. What was I going to rocketfeller plaza for, anyway? The news. My apartment was disgusting, but at least I had been to the gym—I had run the full mile and lifted and pulled, all with the gym to myself. My harem pants still felt even better, and for the first time in me months I ventured into the world in only one waist trainer. Be prepared to be [lost in a revolving door Be cool to the two dudes in blue suits goddamnit I never know where I'm going in this bitch. I can never breath in this bitch and I don't know why. How do you get lost at the rock? Like this: [Infinitely Lost at Rockafeller Plaza] This is why I avoid this place like the plague. Maybe I'm the plague. First of all, there's no track on the floor upstairs. (I've never been upstairs.) It's just store after store of ways to spend money. This is my only pair of clean socks. No shit, this is the reason practicing your mantras on the train becomes dangerous. DANGEROUS. Somewhere in the frenzy, I remember this. Frequency, however, Not yet partial to my own inner self, and empty in the array of superstardom, I become nothing, Only a spectator of celebrity— And now, suddenly. 8 remember this day Why? Suddenly, now, in the Is moment. Where I always have been, waiting for myself— I avoid Rockerfeller plaza at all costs. Why. I heard a grimlin lives here. Now is the time for Skrillex! I would really love you forever if you didn't. Que the Arc! Oh boy, this writer's block is a doozy. The only reason I had even bothered was because it was as if I had been summoned, as if something had clocked in my sense memory where, all of a sudden, looking at an unrelated picture of some kid on Tinee, with his hands covering his mouth the way that Stefon always did, made me immidiately stop whatever I was doing—probably eating tacos or pancakes, insurmountably out of bounds— and pausing the comedian I was watching instead, just to watch Stefon, and in the way that I remembered it all, it made me laugh. Although now, I knew exactly what he was talking about by the avant-grade and strangely abysmal club scene not just of the time, but of any time in New York City— and, somehow summoning a laugh even in the darkness that had been my own distraught and depression in the previous weeks, something of a belly roll laugh might have triggered something in the alrgorithm to send last minute tickets to my email in almost that exact moment. Are they going to tell me to take off my hat?! There was no dress code, They had better not tell me to take off my motherfucking hat. I won't do it. Fuck Seth Meyers . I'm not taking off my hat for Seth Meyers. Oh yeah. That's why I'm here. I found it hard to say that I was there for such a thing; I— I turned off my peripheral vision and hyperfocus. I didn't know there would be music. Goddammit. I had deleted Shazam filming for I love New York, an all but abandoned project—the writer's block had been too real, and now the real rest had come—would I laugh at anything in show show when in reality I wanted to cry? The way the lights kept going up and down as if it were intermission only slightly distracted from the fact that I had never seen a page in real life. THEY EXIST . I had never seen an actual NBC PAGE. GODDAMMIT GET THIS BLUE SUIT LOAFER WEARING MOTHERFUCKER OUT OF MY PERIPHERAL BEFORE I LOSE IT. Shoot a midget at her. What. Just do it. Don't do that. What Don't put the midget in the cannon. What! Thays's what he's here for! I'm a stunt double! This is a stunt. That's a horrible joke. That's not a joke. SHAZAM. WTF IS THIS. Some top 40 bullshit. Good, get it ( I'm never going to have any other l exposure to top 40, ever in my life. ) Congratulations, you've made the A list What?! NO FAIR. What. What does that mean. It means I can't do shit and mandatory attendance to everything. What is everything “Everythin—g.” Man, fuck this. Alright At this moment, I realize I must be some sort of autistic. Let's get this over with… I let the sound of my own mix blare in my ears to drown out the sound of whatever pop singer was on over the loud speakers; I didn't realize there would be music, and I hoped the flutter was good l. Maybe it was the lights, or whatever, but— SUNNI BLU what in the fuck dimention is this . It's the same dimension, you're just drunk. Ah. Now what? I was as uncomfortable as ever, there was a track on the higher level, but it didn't matter, the cattle call was contained inside of velvet ropes— black ones, unlike the typical red ones, and it was at this point I realized that not only had I never seen actual NBC pages— Yo, their skirts are kinda short… RIGHT. I THOUGHT THE PAGES WERE THE PARAGON OF SANCTITY! No, those are, um… Nvm. Maybe the ugly shoes distract from the shortness of their skirts on the general basis. Oh come on, nobody gives a fuck how ugly your shoes are if your skirt is that short! These are facts, Liz. No, I'm serious what dimention is this. I already told you. I had to ask for directions three times just get here. THIS IS MY LEVEL. why is your level on acid. Cause. This is—just— Where I'm at. CUT TO: Jimmy Fallon after Mardi Gras's. Come on that's not fair! {Enter The Multiverse} What exactly isn't fair?! He's in all the scenes. Well, how else are you going to explain a time traveling helicopter?! Got him. THERES MY INVISIBLE MOTORCYCLE. I'm not going to pa— Goddamn it. I'm not going to p— It actually hurt not to write and just stand there; but I still didn't feel like myself—or sound like myself—or look like myself; I was playing a character, I just didnt know who. As I moved forward in line, the music began to fade away behind me and into the nothingness that was whatever was behind, in front of, and all around me. I hated cattle calls, but after all, I was still just a fan and as the world began to fold into chaos, I realized that my pants were falling off of me, though I had been feeling fat, and walking, and running, and cycling, and protein shaking—the only thing that had gained any extra weight was my ass, which was exactly what I was intending on hiding with my same old usual harems. My blonde hair made it so that I stuck out like a sore thumb, but that didn't matter, I was a walking statement piece and almost in a fit of tears just thinking about my own status; the NBC pages probably all had crazy incredible accolades and numerous degrees and achievements—what was I, if anything at all— ? I had put the candles out, but had I left the stove on? Did I really unplug the nail dryer and leave the stove on? I had almost washed all of the dishes, but stopped just short of right on time to leave; my producer brain was on fire and wanted more pancakes, but however hard I tried I could not find where I had placed my EBT card; probably for the better—celebrities didn't carry EBT cards, and even my awkward general being thrown off by the doorman or security— —whichever I wasn't sure— standing outside of the roller rink— probably ice this time of year, by the looks of the Zamboni in the foreground of it… ‘Don't stop writing, no matter what. ‘ Dammit, dammit dammit— That seems inappropriate. I told you to get this motherfucker out of my peripheral before something— Nevermind, don't write that. [redacted] (But imma remember this shit cause it's heavy.) A remarkable and accidental tableau, My feet flat to the floor, as my ankles bare, This is my only pair of hole-less socks. I feel so much better with my back against the wall and Listening to mau5 and, Not giving a fuck about the music playing Or the people watching But keeping it for later Forgetting how to codeswitch, Just an ever so limited existence Trying not to stick out like a sore thumb in the wrong world It's a long way up, But even longer way down, And in all the demoralizing humiliation and emasculation, I realize I'm no man at all, No man at all I realize I'm no man at all, No man at all, No mana I realized my son's Lego Lamborghini should be waiting for me as I returned to my apartment in Brooklyn probably starting but pretending not to care; I winced at everything— this was a dangerous disaster, to even be in the building at all and edging closer to death were the secrets I kept that were not only secrets, but non existences. Nothing in nothing and nothing— Oh shit, is the suffering done? This is the end of the End of the end It's the Beginning of the end It's the end of the beginning This will be the end Of the end Of the end, This will be the end of the end Of the end Of the end Of the beginning Of the end Of the beginning of the end. This will be the end Of the end Of the end Of the beginning of the beginning Of the end of the end Of the beginning Of the end This will be the end Of the beginning Of the beginning Of the beginning Of the end Of the end Of the end This will be the end Of the beginning of the beginning This will be the beginning of the beginning of the beginning This will be the beginning, The beginning of the end This will be the end of the end of the end This will be the end of the end of the end This will be the end (This will be the end) Of the beginning This will be the beginning The beginning of the beginning Of the end My friends. LET US COMMECE! All of it, this is recorded history, Smoke and mirrors, here portions and pardons This is probably why can't breathe at the rock Was I here last time; I choked last time I wrote nothing remarkable at all (Nothing remarkable at all.) I love getting lost at the rock Okay, this is the host— This is the host of the show (I think I lost my lunch before.) I was at a show, I never woke up, Okay; This is the host This is the host (This is the host) This is the host. Cue the Nirvana; Curtains go up, I don't want to see the show, I just want to host it. I don't want to get lost no more On the way to the rock Or the store Cause only one train goes there I wanna climb the straits to the top Get lost at the rock, Guess this isn't he host huh This is the lost god, That was a long walk The top of the rock off is a long jump And I'm still in talks how's every morning Someone told me not to ignore you So, this is the host, huh. Someone told me, go hard or go home (Almost time tknkove) Parenthesises, please and—Parenthetical, hypotheticals and paleontology's, Please, I need a mixologist (And anthologist) Please slow down to peace, Mr poltergeist, Please Mr poltergeist The ghost of Mr giest I'm doing a hiest Please, slow down mister poltergeist, Please for the peace Mr. Poltergeist, Or what have you? How old are you, 40. I'm the whole medium and still, Nice to meat you sir. A house made of mediums I hope that shock, And I hop to the rock there's still something in it A pogo stick Or a poltergeist Slow down, poltergeist. Terrible timing, Victoria Beckham and monsuier, Please Mr, I mean it no more— If I'm Mr ooltergieat (A policeman and polgergeist) Please, sir, no jokes. All sandwhich, no buns and pastrmi, And all the God, I'm going cold, I'm going ghost again And a the god, on all the rocks, I'm going old, I'm going cold again; On all the God on all the rocks, I'm going God, I'm going old again Hold on again, mi got a song again? I'm just a serviceman WATCH OUT FOR THE DOORMAN. MORE FUEL. So all the Rockerfeller plazas on all the earths aim alll yhr parallel dimensions can actually communicate with each other RADIO CITY BABBBBBBBYYYYYYY! OH GOD. WHAT ARE YOU DOING HERE Did you get his dog's name!? I think so. Good. [meniacal rubbing of hands] good. Cue the nirvana. Cue the m— Mitosis. The migos. Nah, I can't catch the flow. There it is. [the flow is a literal] Something medicinal in this meniacal, is this I spy a specscle, monocle— monopoly, Time to go, it's the devil at my left; Time for the fight against darkness, And it all is, Cause this is the ark, Noah This is the arc, God. This is apartheid and apart from that. You're fired. What. You heard me. But—I'm Seth Meyers. That's debatable. I am! I'm Seth Meyers. If you say so. This is nonsense. It's not nonsense. It is nonsense. And it's also impossible; cause this is my show. It's my show, I'M SETH MEYERS. Debatable, Not debatable. I'm ME. THAT'S ME. Debatable. I can't even hear the words, But the bass is so fire, I summon Shazam! …I want a ham sandwhich. Oh good! He's alive. Ham. Sandwhich. What the fuck happened buddy?! Where were you man?! —Zoolander. What. disleylandhamsandwhich. Get him a sandwhich!!!!! YO QUIERO CUBANO. Here's your sandwhich. CUBANO. Remember what you look like Who you are What your place is What you weigh, And Check your status Remember how still started What your mark is And what happened to your wallet; Did you leave the stove on Do you put the show on; Did you miss your mark Your mom was hotter Please remember the circumstances In which you—- [BLACKOUT] After several days gone completely missing, Jimmy Fallon is found under the craft services table sleeping peacefully. The apparatus I entered in with Is not adjusted to this condition The biometrics are non concurrent; {enter the multiverse} I felt tragic. By the time I got back to my apartment, my ribcage was showing again—although I had only been wearing one waist trainer, it was the skimpy one, and it was already wearing, it was after all eight dollars. Really and once and for all, something had come over me at Rockerfeller plaza that I didn't understand. I was more awkward and nervous than usual, and sure that I should have eaten, but couldn't —even after a long gym session, there was no time for food before the show, and I had no stomach for it. I chose to as much as I could ignore the code switching, and the more I picked it up, the further my mind began to drift. —a door slammed. My documents were probably compromised, and my phone hacked which I might have guessed, but continuing the thought I had often wondered how or why anything could have possibly known what I had written, or how—or how anyone would know what I had written, or of the things I had written, and most importantly of all—what did I write?! Most of the previous months' entries into the festival project were a blank, and the time I had spent considerably enough sifting through whatever masked man acting in part of Fallon, whoever he really was had been turbulent, as if I had been disfigured to be brainwashed into half a mind—then, slowly peeking back the layers of such a chaotic artifact of time and this, Seth Meyers, to whom now I had become a loyal fan, an actual fan—and had noticed something ingenuously crafted here. A genuine and talented, very kind and gifted man, who was not in any sense miserable or in peril. Peril, so to speak, as I remembered the almost villainous approach that the decent into madness had accompanied this Fallon and his mask, and besides this was the assumption that Seth Meyers, though professionally trained as such, seemed happy. Fallon did not. We had all learned to craft masks in order to protect our inner selves—however, with such a veil lifted as the partitioned screen of all does, this spoke to me with numerous volumes and sometimes even screamed, with the ethics of no worse a gentleman than some surgeon soldier or sailor and no more a nobleman than a king or god itself; I had not been Shocked and all but murmured even to just the slightest gawk of just an awkward cry, a muster of some shallow disaster which had called me to all of them— to whom I had loved and yet somehow not known, at least being here—and here I was, slightly convulsed, bearing no armor and gripping at the fortitude of death's barriers; On wheels with no bearings plummeted towards a forged death of sorts, by my own hands but also at the hands of others, the forgery calling from the halls of a place I had known as once my own fortress; but was no more. I belonged and now, almost with gratitude, to the eye of all gods, and all things that moved. No cherished nature, perhaps, was this into my own eye, but of disgust for what I had not yet accomplished, and still might never— I was a skull and crossbones with no love, and nothing known at all besides my own. —Tales of a superstar DJ “16 Songs” I got it. What's that. The thing that sets Seth Meyers apart from the other hosts. What is it? Seth Meyers is not a host—he's an anchor. Goddammit, you're right . I know I'm right. GODDAMIT. It just took me this long to figure it out . Great. Now how long's it gonna get you to take this thing fixed. Possibly forever. Entaer The Multiverse} [The Festival Project.™] COPYRIGHT © THE FESTIVAL PROJECT 2024 ALL RIGHTS RESERVED. ©

“Seth Meyers And the Cauldron of Doom” OMG— YOU have a cauldron of doom?! I have a cauldron of doom!!! DO NOT SHAKE THIS SNOWGLOBE. I had been avoiding Rockefeller plaza for months as it was, without the sometimes accidental ending up there anyway, and I thought not once but twice or three times about changing into my regular pants so that the deep pockets could hold my keys and passports sans wallet— or a purse and considered taking a notebook as well; on the list of prohibited items were backpacks and large bags, and though the dress code seemed to be null in void at all, I was happy to be able to wear my hat at least— and almost prepared to be dogged out, the last min it e change into my harem pants would probably be the comfortable choice; looking intentionally dressed down as a statement—a broad statement that I wasn't looking to be noticed at all, or trying to be noticed. The guest for the show was nearly an EGOT winner, probably younger, and definitely skinner and more beautiful than I was; a black woman, but a British woman, and it would be almost entirely impossible to think that besides Whoopi Goldberg, an American black woman would strive to win such a thing as an EGOT herself. Still, I was looking for a cure to the writer's block and crippling depression that I had been in, however—knowing who the president of Peacock was, and after the elections at all's though I knew NBC to be left-leaning— I didn't feel at all as if I would ever belong on the stage, and was quite happily taking my place as simply a fan…and audience member, though ready to creep back into obscurity, and probably more likely than not with a pint of Ben and Jerry's after the show. I had gone to see Drew Barrymore sand makeup, and would do the same, but only as a proclamation that I had read Tina Fey's book nearly religiously now rounding three times, and I almost wish I had an oversized black t-shirt which read “hot water heater” to accompany my lax look and blonde hair—a testament to her correctness standing, as the grossities of tinder loved “the blonde”, almost as if, without the hair I would be ugly, and just as much in the same breath, unworthy of such status anyway. But more than anything, I just wanted to be able to write again, at least for my own sake, and certainly not for anyone else's. I was still in hiatus, for the better, and had not completely recovered from the unbearable racism and parallel of doom the election had tossed me into with trajectory—in this world—supposedly “fascist”. I was comfortable enough in the jeans, but had nowhere to put my phone. I was ready to be dogged out and shown what a real a list celebrity looked like, and why I simply wasn't one. I left the house with a sink full of dishes, an unmade bed, and a pile of laundry unfolded—a pile of books in boxes I had collected for my son but would cost too much to send—almost as a testament to his sick I had been since the election. In this world, I was just another poor black fat single mother— a dead beat living in poverty. In trump's world, I was an ugly, poor nothing. Everywhere I had gone about the past week, the rich seemed richer and the poor poorer, the whites whiter and the blacks blacker, good gone and evil fleeting, with the return of the motorcycles and pieces of me dying, simply giving up. I planned my return to the workforce, and the eventual fortitude of my freedom; the wealthy had become more arrogant, and the rest of us more distraught. What was I going to rocketfeller plaza for, anyway? The news. My apartment was disgusting, but at least I had been to the gym—I had run the full mile and lifted and pulled, all with the gym to myself. My harem pants still felt even better, and for the first time in me months I ventured into the world in only one waist trainer. Be prepared to be [lost in a revolving door Be cool to the two dudes in blue suits goddamnit I never know where I'm going in this bitch. I can never breath in this bitch and I don't know why. How do you get lost at the rock? Like this: [Infinitely Lost at Rockafeller Plaza] This is why I avoid this place like the plague. Maybe I'm the plague. First of all, there's no track on the floor upstairs. (I've never been upstairs.) It's just store after store of ways to spend money. This is my only pair of clean socks. No shit, this is the reason practicing your mantras on the train becomes dangerous. DANGEROUS. Somewhere in the frenzy, I remember this. Frequency, however, Not yet partial to my own inner self, and empty in the array of superstardom, I become nothing, Only a spectator of celebrity— And now, suddenly. 8 remember this day Why? Suddenly, now, in the Is moment. Where I always have been, waiting for myself— I avoid Rockerfeller plaza at all costs. Why. I heard a grimlin lives here. Now is the time for Skrillex! I would really love you forever if you didn't. Que the Arc! Oh boy, this writer's block is a doozy. The only reason I had even bothered was because it was as if I had been summoned, as if something had clocked in my sense memory where, all of a sudden, looking at an unrelated picture of some kid on Tinee, with his hands covering his mouth the way that Stefon always did, made me immidiately stop whatever I was doing—probably eating tacos or pancakes, insurmountably out of bounds— and pausing the comedian I was watching instead, just to watch Stefon, and in the way that I remembered it all, it made me laugh. Although now, I knew exactly what he was talking about by the avant-grade and strangely abysmal club scene not just of the time, but of any time in New York City— and, somehow summoning a laugh even in the darkness that had been my own distraught and depression in the previous weeks, something of a belly roll laugh might have triggered something in the alrgorithm to send last minute tickets to my email in almost that exact moment. Are they going to tell me to take off my hat?! There was no dress code, They had better not tell me to take off my motherfucking hat. I won't do it. Fuck Seth Meyers . I'm not taking off my hat for Seth Meyers. Oh yeah. That's why I'm here. I found it hard to say that I was there for such a thing; I— I turned off my peripheral vision and hyperfocus. I didn't know there would be music. Goddammit. I had deleted Shazam filming for I love New York, an all but abandoned project—the writer's block had been too real, and now the real rest had come—would I laugh at anything in show show when in reality I wanted to cry? The way the lights kept going up and down as if it were intermission only slightly distracted from the fact that I had never seen a page in real life. THEY EXIST . I had never seen an actual NBC PAGE. GODDAMMIT GET THIS BLUE SUIT LOAFER WEARING MOTHERFUCKER OUT OF MY PERIPHERAL BEFORE I LOSE IT. Shoot a midget at her. What. Just do it. Don't do that. What Don't put the midget in the cannon. What! Thays's what he's here for! I'm a stunt double! This is a stunt. That's a horrible joke. That's not a joke. SHAZAM. WTF IS THIS. Some top 40 bullshit. Good, get it ( I'm never going to have any other l exposure to top 40, ever in my life. ) Congratulations, you've made the A list What?! NO FAIR. What. What does that mean. It means I can't do shit and mandatory attendance to everything. What is everything “Everythin—g.” Man, fuck this. Alright At this moment, I realize I must be some sort of autistic. Let's get this over with… I let the sound of my own mix blare in my ears to drown out the sound of whatever pop singer was on over the loud speakers; I didn't realize there would be music, and I hoped the flutter was good l. Maybe it was the lights, or whatever, but— SUNNI BLU what in the fuck dimention is this . It's the same dimension, you're just drunk. Ah. Now what? I was as uncomfortable as ever, there was a track on the higher level, but it didn't matter, the cattle call was contained inside of velvet ropes— black ones, unlike the typical red ones, and it was at this point I realized that not only had I never seen actual NBC pages— Yo, their skirts are kinda short… RIGHT. I THOUGHT THE PAGES WERE THE PARAGON OF SANCTITY! No, those are, um… Nvm. Maybe the ugly shoes distract from the shortness of their skirts on the general basis. Oh come on, nobody gives a fuck how ugly your shoes are if your skirt is that short! These are facts, Liz. No, I'm serious what dimention is this. I already told you. I had to ask for directions three times just get here. THIS IS MY LEVEL. why is your level on acid. Cause. This is—just— Where I'm at. CUT TO: Jimmy Fallon after Mardi Gras's. Come on that's not fair! {Enter The Multiverse} What exactly isn't fair?! He's in all the scenes. Well, how else are you going to explain a time traveling helicopter?! Got him. THERES MY INVISIBLE MOTORCYCLE. I'm not going to pa— Goddamn it. I'm not going to p— It actually hurt not to write and just stand there; but I still didn't feel like myself—or sound like myself—or look like myself; I was playing a character, I just didnt know who. As I moved forward in line, the music began to fade away behind me and into the nothingness that was whatever was behind, in front of, and all around me. I hated cattle calls, but after all, I was still just a fan and as the world began to fold into chaos, I realized that my pants were falling off of me, though I had been feeling fat, and walking, and running, and cycling, and protein shaking—the only thing that had gained any extra weight was my ass, which was exactly what I was intending on hiding with my same old usual harems. My blonde hair made it so that I stuck out like a sore thumb, but that didn't matter, I was a walking statement piece and almost in a fit of tears just thinking about my own status; the NBC pages probably all had crazy incredible accolades and numerous degrees and achievements—what was I, if anything at all— ? I had put the candles out, but had I left the stove on? Did I really unplug the nail dryer and leave the stove on? I had almost washed all of the dishes, but stopped just short of right on time to leave; my producer brain was on fire and wanted more pancakes, but however hard I tried I could not find where I had placed my EBT card; probably for the better—celebrities didn't carry EBT cards, and even my awkward general being thrown off by the doorman or security— —whichever I wasn't sure— standing outside of the roller rink— probably ice this time of year, by the looks of the Zamboni in the foreground of it… ‘Don't stop writing, no matter what. ‘ Dammit, dammit dammit— That seems inappropriate. I told you to get this motherfucker out of my peripheral before something— Nevermind, don't write that. [redacted] (But imma remember this shit cause it's heavy.) A remarkable and accidental tableau, My feet flat to the floor, as my ankles bare, This is my only pair of hole-less socks. I feel so much better with my back against the wall and Listening to mau5 and, Not giving a fuck about the music playing Or the people watching But keeping it for later Forgetting how to codeswitch, Just an ever so limited existence Trying not to stick out like a sore thumb in the wrong world It's a long way up, But even longer way down, And in all the demoralizing humiliation and emasculation, I realize I'm no man at all, No man at all I realize I'm no man at all, No man at all, No mana I realized my son's Lego Lamborghini should be waiting for me as I returned to my apartment in Brooklyn probably starting but pretending not to care; I winced at everything— this was a dangerous disaster, to even be in the building at all and edging closer to death were the secrets I kept that were not only secrets, but non existences. Nothing in nothing and nothing— Oh shit, is the suffering done? This is the end of the End of the end It's the Beginning of the end It's the end of the beginning This will be the end Of the end Of the end, This will be the end of the end Of the end Of the end Of the beginning Of the end Of the beginning of the end. This will be the end Of the end Of the end Of the beginning of the beginning Of the end of the end Of the beginning Of the end This will be the end Of the beginning Of the beginning Of the beginning Of the end Of the end Of the end This will be the end Of the beginning of the beginning This will be the beginning of the beginning of the beginning This will be the beginning, The beginning of the end This will be the end of the end of the end This will be the end of the end of the end This will be the end (This will be the end) Of the beginning This will be the beginning The beginning of the beginning Of the end My friends. LET US COMMECE! All of it, this is recorded history, Smoke and mirrors, here portions and pardons This is probably why can't breathe at the rock Was I here last time; I choked last time I wrote nothing remarkable at all (Nothing remarkable at all.) I love getting lost at the rock Okay, this is the host— This is the host of the show (I think I lost my lunch before.) I was at a show, I never woke up, Okay; This is the host This is the host (This is the host) This is the host. Cue the Nirvana; Curtains go up, I don't want to see the show, I just want to host it. I don't want to get lost no more On the way to the rock Or the store Cause only one train goes there I wanna climb the straits to the top Get lost at the rock, Guess this isn't he host huh This is the lost god, That was a long walk The top of the rock off is a long jump And I'm still in talks how's every morning Someone told me not to ignore you So, this is the host, huh. Someone told me, go hard or go home (Almost time tknkove) Parenthesises, please and—Parenthetical, hypotheticals and paleontology's, Please, I need a mixologist (And anthologist) Please slow down to peace, Mr poltergeist, Please Mr poltergeist The ghost of Mr giest I'm doing a hiest Please, slow down mister poltergeist, Please for the peace Mr. Poltergeist, Or what have you? How old are you, 40. I'm the whole medium and still, Nice to meat you sir. A house made of mediums I hope that shock, And I hop to the rock there's still something in it A pogo stick Or a poltergeist Slow down, poltergeist. Terrible timing, Victoria Beckham and monsuier, Please Mr, I mean it no more— If I'm Mr ooltergieat (A policeman and polgergeist) Please, sir, no jokes. All sandwhich, no buns and pastrmi, And all the God, I'm going cold, I'm going ghost again And a the god, on all the rocks, I'm going old, I'm going cold again; On all the God on all the rocks, I'm going God, I'm going old again Hold on again, mi got a song again? I'm just a serviceman WATCH OUT FOR THE DOORMAN. MORE FUEL. So all the Rockerfeller plazas on all the earths aim alll yhr parallel dimensions can actually communicate with each other RADIO CITY BABBBBBBBYYYYYYY! OH GOD. WHAT ARE YOU DOING HERE Did you get his dog's name!? I think so. Good. [meniacal rubbing of hands] good. Cue the nirvana. Cue the m— Mitosis. The migos. Nah, I can't catch the flow. There it is. [the flow is a literal] Something medicinal in this meniacal, is this I spy a specscle, monocle— monopoly, Time to go, it's the devil at my left; Time for the fight against darkness, And it all is, Cause this is the ark, Noah This is the arc, God. This is apartheid and apart from that. You're fired. What. You heard me. But—I'm Seth Meyers. That's debatable. I am! I'm Seth Meyers. If you say so. This is nonsense. It's not nonsense. It is nonsense. And it's also impossible; cause this is my show. It's my show, I'M SETH MEYERS. Debatable, Not debatable. I'm ME. THAT'S ME. Debatable. I can't even hear the words, But the bass is so fire, I summon Shazam! …I want a ham sandwhich. Oh good! He's alive. Ham. Sandwhich. What the fuck happened buddy?! Where were you man?! —Zoolander. What. disleylandhamsandwhich. Get him a sandwhich!!!!! YO QUIERO CUBANO. Here's your sandwhich. CUBANO. Remember what you look like Who you are What your place is What you weigh, And Check your status Remember how still started What your mark is And what happened to your wallet; Did you leave the stove on Do you put the show on; Did you miss your mark Your mom was hotter Please remember the circumstances In which you—- [BLACKOUT] After several days gone completely missing, Jimmy Fallon is found under the craft services table sleeping peacefully. The apparatus I entered in with Is not adjusted to this condition The biometrics are non concurrent; {enter the multiverse} I felt tragic. By the time I got back to my apartment, my ribcage was showing again—although I had only been wearing one waist trainer, it was the skimpy one, and it was already wearing, it was after all eight dollars. Really and once and for all, something had come over me at Rockerfeller plaza that I didn't understand. I was more awkward and nervous than usual, and sure that I should have eaten, but couldn't —even after a long gym session, there was no time for food before the show, and I had no stomach for it. I chose to as much as I could ignore the code switching, and the more I picked it up, the further my mind began to drift. —a door slammed. My documents were probably compromised, and my phone hacked which I might have guessed, but continuing the thought I had often wondered how or why anything could have possibly known what I had written, or how—or how anyone would know what I had written, or of the things I had written, and most importantly of all—what did I write?! Most of the previous months' entries into the festival project were a blank, and the time I had spent considerably enough sifting through whatever masked man acting in part of Fallon, whoever he really was had been turbulent, as if I had been disfigured to be brainwashed into half a mind—then, slowly peeking back the layers of such a chaotic artifact of time and this, Seth Meyers, to whom now I had become a loyal fan, an actual fan—and had noticed something ingenuously crafted here. A genuine and talented, very kind and gifted man, who was not in any sense miserable or in peril. Peril, so to speak, as I remembered the almost villainous approach that the decent into madness had accompanied this Fallon and his mask, and besides this was the assumption that Seth Meyers, though professionally trained as such, seemed happy. Fallon did not. We had all learned to craft masks in order to protect our inner selves—however, with such a veil lifted as the partitioned screen of all does, this spoke to me with numerous volumes and sometimes even screamed, with the ethics of no worse a gentleman than some surgeon soldier or sailor and no more a nobleman than a king or god itself; I had not been Shocked and all but murmured even to just the slightest gawk of just an awkward cry, a muster of some shallow disaster which had called me to all of them— to whom I had loved and yet somehow not known, at least being here—and here I was, slightly convulsed, bearing no armor and gripping at the fortitude of death's barriers; On wheels with no bearings plummeted towards a forged death of sorts, by my own hands but also at the hands of others, the forgery calling from the halls of a place I had known as once my own fortress; but was no more. I belonged and now, almost with gratitude, to the eye of all gods, and all things that moved. No cherished nature, perhaps, was this into my own eye, but of disgust for what I had not yet accomplished, and still might never— I was a skull and crossbones with no love, and nothing known at all besides my own. —Tales of a superstar DJ “16 Songs” I got it. What's that. The thing that sets Seth Meyers apart from the other hosts. What is it? Seth Meyers is not a host—he's an anchor. Goddammit, you're right . I know I'm right. GODDAMIT. It just took me this long to figure it out . Great. Now how long's it gonna get you to take this thing fixed. Possibly forever. {Enter The Multiverse} [The Festival Project.™] COPYRIGHT © THE FESTIVAL PROJECT 2024 ALL RIGHTS RESERVED. ©

Um tipo de divisão celular que ocorre em todas as células eucarióticas. Separe trinta minutinhos do seu dia e descubra, com a Mila Massuda, sobre o processo onde uma célula dá origem a duas outras células idênticas. Apresentação: Mila Massuda (@milamassuda) Roteiro: Mila Massuda (@milamassuda) e Emilio Garcia (@emilioblablalogia) Revisão de Roteiro: Luisa Kahakura (@lukahakura) Técnica de Gravação: Julianna Harsche (@juvisharsche) Editora: Lilian Correa (@_lilianleme) Mixagem e Masterização: Juscelino Filho (@juscelino_filho) Produção: Prof. Vítor Soares (@profvitorsoares), Matheus Herédia (@Matheus_Heredia) e BláBláLogia (@blablalogia) Gravado e editado nos estúdios TocaCast, do grupo Tocalivros (@tocalivros) REFERÊNCIAS CHEESEMAN, I. M.; DESAI, A. Molecular architecture of the kinetochore–microtubule interface. Nature Reviews Molecular Cell Biology, v. 9, n. 1, p. 33–46, jan. 2008. CREMER, T.; CREMER, C. Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nature Reviews Genetics, v. 2, n. 4, p. 292–301, abr. 2001. HAGSTROM, K. A.; MEYER, B. J. Condensin and cohesin: more than chromosome compactor and glue. Nature Reviews Genetics, v. 4, n. 7, p. 520–534, jul. 2003. HIRANO, T. At the heart of the chromosome: SMC proteins in action. Nature Reviews Molecular Cell Biology, v. 7, n. 5, p. 311–322, maio 2006. MITCHISON, T. J.; SALMON, E. D. Mitosis: a history of division. Nature Cell Biology, v. 3, n. 1, p. E17–E21, jan. 2001. PARK, S. et al. The mammalian midbody and midbody remnant are assembly sites for RNA and localized translation. Developmental Cell, v. 58, n. 19, p. 1917-1932.e6, 1 out. 2023. PAWELETZ, N. Walther Flemming: pioneer of mitosis research. Nature Reviews Molecular Cell Biology, v. 2, n. 1, p. 72–75, jan. 2001. SATZINGER, H. Theodor and Marcella Boveri: chromosomes and cytoplasm in heredity and development. Nature Reviews Genetics, v. 9, n. 3, p. 231–238, mar. 2008.

Episode Summary: In this transformative episode of The Arcturian Playground, we dive deep into the metaphysical concept of "Soulular Mitosis" with guidance from the Arcturian Collective Thingy. This discussion explores the intricate and dynamic processes of spiritual evolution, likening the soul's growth to the biological process of mitosis but on a cosmic scale.Key Concepts Discussed:Soul as a Cosmic Beanstalk:The soul is envisioned as a continuously growing beanstalk, branching out into various directions and dimensions, each representing different aspects of consciousness and spiritual evolution.Energetic Patterns and Connections:The episode delves into how our souls are intertwined with the energetic patterns of the universe, specifically within the Arcturus solar system, suggesting a deep, intrinsic connection to the cosmos.Metaphysical Mitosis:"Soulular Mitosis" is introduced as a process where the soul constantly divides and multiplies, forming new consciousness units that remain interconnected. This concept is illustrated through the metaphor of a cactus, with new buds and branches continually emerging.Integration of Scientific and Spiritual Insights:The discussion bridges scientific understanding with spiritual insights, examining how atoms, subatomic particles, and waves contribute to our understanding of soul structures and their interactions with the universe.Philosophical Reflections on Soul Damage and Repair:Contrasting viewpoints from the book The Seat of the Soul are explored, particularly the idea that the soul can be damaged by earthly experiences versus the Arcturian perspective of the soul's indestructibility.Consciousness Evolution and the Cosmic Ecosystem:Insights into how consciousness evolves through interactions and relationships at various levels of existence, from the subatomic to the cosmic, are discussed, highlighting the interconnected nature of all beings.Call to Awareness and Connectivity:The episode encourages listeners to recognize their own part in the vast, interconnected soul system, urging a deeper awareness of their soul connections and the continuous growth and development of their spiritual selves.Listening Experience: This episode invites you to contemplate the boundless possibilities of your soul's journey and its interconnections with the cosmic fabric. Through a blend of metaphysical narratives and grounded discussions, listeners are encouraged to expand their perceptions and embrace a more interconnected view of existence.For Further Reflection: Consider how the concept of "Soulular Mitosis" might change your view of personal growth and spiritual evolution. How does it affect your understanding of your place in the universe?Join us on this cosmic journey as we explore the depths of the soul and its ceaseless evolution within the universal tapestry. This episode is not just a listening experience but an invitation to expand your consciousness and embrace the interconnectedness of all life.

The rewind mini series is back! This time, we're discuss the two forms of eukaryotic cell division, mitosis and meiosis. Sources for this episode: Campbell, N. A., Urry, L. A., Cain, M. L., Wasserman, S. A., Minorsky, P. V. and Reece, J. B. (2018), Biology: a global approach, 11th edition (Global Edition), Harlow, Pearson Education Limited. Hine, R. (2019), A Dictionary of Biology (Oxford Quick Reference), 8th edition, Oxford, Oxford University Press. Russell, P. J. (2006), iGenetics: A Molecular Approach. San Francisco: Pearson Education, Inc.

In this episode of the Pediatric and Developmental Pathology Podcast, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Mai (Mike) He of Washington University School of Medicine in St. Louis and Grady Yu, alum of the Whiting School of Engineering at The Johns Hopkins University, about their article in Pediatric and Developmental Pathology: Automated Tumor Count for Mitosis-Karyorrhexis Index Determination in Neuroblastoma Using Whole Slide Image and Qupath, an Image Analytic Software   Featured public domain music: Summer Pride by Loyalty Freak

In DejaVue episode number nine, Tim Benniks joins Alex discussing how he used Vue in huge applications and how Tim and his team built 3000 websites for a single brand that most of you know - Louis Vuitton.In addition, Tim shares his journey from becoming a nurse to eventually learn web development. Learn which benefits Vue brought compared to the old jQuery application, how Tim and his team migrated a huge system step by step and more!Enjoy the episode!Chapters(00:00) - Start and Guest Introduction (01:34) - From becoming a Nurse to becoming a Developer (06:49) - Building Social Network before Facebook (10:33) - Getting into Vue.js and Abandoning jQuery (16:01) - Reducing Bugs with Vue.js (19:33) - Accessibility - Reaching AA or AAA (26:16) - Balancing the Stakeholder Needs (30:39) - 3000 Websites with Vue.js for one Company (32:49) - Building your own Component Library? (35:40) - Cleaning up Technical Debt at Louis Vuitton (38:23) - Gradually upgrading legacy LV software (43:43) - Why not React or Angular? (52:40) - Mitosis (55:13) - Outro Links and ResourcesTim's episode on the "We Belong Here" podcastEpisode #E001 The Need for SSRGruntGulpWCAG for AccessibilityVue Route AnnouncerRoute Announcer in NuxtKnockout.jsAccessibility Needs OverviewPartytownCloudFlare ZarazEpisode #E007 From Code to DevRel and LeadershipTim's "Team First" TalkStorybookMigrating to Nuxt 4 Now?!Tim's "A Vue into Rock & Roll Part 2" talkMitosis

LM

Back with some SCIENCE SH*T! J.Daae is talking about MITOSIS aka cell replication! This episode covers how a cell slipts into two, when does this happen, and what is the process in the cell that is helping one become two. ——————————— ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠FOLLOW US on INSTAGRAM @HomoInTraining⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Find us on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook! LIKE & FOLLOW our page!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ EMAIL us your science queeries!: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠HomoInTrainingPodcast@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ——————————— Music Credit: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Jazzy Abstract Beat by Coma-Media⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ——————————— --- Send in a voice message: https://podcasters.spotify.com/pod/show/homointraining/message

On this episode, you'll learn...

Multidisciplinary artist Eartheater talks with NYU computational biologist and artist, Dr. Elizabeth Hénaff about cell division, snails, horseshit, gut biome health, artist residencies and more at this very special live event! This episode was recorded at DEMO2023, presented by NEW INC and the New Museum, June 2023

Antonio Cisneros, vocalista del grupo Mitosis, murió en Tucson, Arizon Este sábado se llevará a cabo la audiencia incial en la que se informará la acusación existente en contra de los seis detenido, por el presunto homicidio del empresario Íñigo ArenasUna amenaza de bomba en la Torre Eiffel en París, obligó a las autoridades a desalojar a los visitantes.Más información en nuestro podcast

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body. From the skin to the brain, muscles to blood, and everything in between, these countless cells collaborate harmoniously to keep us alive and well, but how do these cells know what to do? When a cell divides, how does it know that it's exact counterpart should do the same thing as the original. Researchers at the Goren Lab at UC San Diego are working to determine just that. They discuss some of the work they are doing to learn more about the human body beyond the cellular level [Health and Medicine] [Science] [Show ID: 38259]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body. From the skin to the brain, muscles to blood, and everything in between, these countless cells collaborate harmoniously to keep us alive and well, but how do these cells know what to do? When a cell divides, how does it know that it's exact counterpart should do the same thing as the original. Researchers at the Goren Lab at UC San Diego are working to determine just that. They discuss some of the work they are doing to learn more about the human body beyond the cellular level [Health and Medicine] [Science] [Show ID: 38259]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body. From the skin to the brain, muscles to blood, and everything in between, these countless cells collaborate harmoniously to keep us alive and well, but how do these cells know what to do? When a cell divides, how does it know that it's exact counterpart should do the same thing as the original. Researchers at the Goren Lab at UC San Diego are working to determine just that. They discuss some of the work they are doing to learn more about the human body beyond the cellular level [Health and Medicine] [Science] [Show ID: 38259]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body. From the skin to the brain, muscles to blood, and everything in between, these countless cells collaborate harmoniously to keep us alive and well, but how do these cells know what to do? When a cell divides, how does it know that it's exact counterpart should do the same thing as the original. Researchers at the Goren Lab at UC San Diego are working to determine just that. They discuss some of the work they are doing to learn more about the human body beyond the cellular level [Health and Medicine] [Science] [Show ID: 38259]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body. From the skin to the brain, muscles to blood, and everything in between, these countless cells collaborate harmoniously to keep us alive and well, but how do these cells know what to do? When a cell divides, how does it know that it's exact counterpart should do the same thing as the original. Researchers at the Goren Lab at UC San Diego are working to determine just that. They discuss some of the work they are doing to learn more about the human body beyond the cellular level [Health and Medicine] [Science] [Show ID: 38259]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body. From the skin to the brain, muscles to blood, and everything in between, these countless cells collaborate harmoniously to keep us alive and well, but how do these cells know what to do? When a cell divides, how does it know that it's exact counterpart should do the same thing as the original. Researchers at the Goren Lab at UC San Diego are working to determine just that. They discuss some of the work they are doing to learn more about the human body beyond the cellular level [Health and Medicine] [Science] [Show ID: 38259]

The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body. From the skin to the brain, muscles to blood, and everything in between, these countless cells collaborate harmoniously to keep us alive and well, but how do these cells know what to do? When a cell divides, how does it know that it's exact counterpart should do the same thing as the original. Researchers at the Goren Lab at UC San Diego are working to determine just that. They discuss some of the work they are doing to learn more about the human body beyond the cellular level [Health and Medicine] [Science] [Show ID: 38259]

What does symmetry and self-similarity between life and intelligence mean for the nature of reality? How are neurones like genes?  Today we have the extraordinary Fractal Brain Theory to discuss. After episode #38 about the World as a Neural Network, with Russian physicist and computer scientist Vitaly Vanchurin, i've become more open to a unified theory of universe that reconciles quantum mechanics with general relativity, as Vanchurin's equations seem to offer. So when I was recommended today's guest's Fractal Brain Theory by one of the wonderful listeners, I was curious if a little sceptical given all the psychedelic hype about fractal geometry. So a symmetrical theory of repeating self-similar, self-modifying behaviour in the universe is not so far from the vision of the universe as a thriving, adaptable neural network. And according to today's guest the symmetry directly connects the often divorced worlds of neurones, brains and intelligence with the world of genes, evolution and life.  He is multi-disciplinary researcher, computer scientist, musician and author Wai H Tsang. A self-taught thinker in the world of neurology, evolutionary biology, consciousness and philosophy of mind, Tsang is in the unique position of combining these traditions into a single theory of brain, that promises to solve even the hard problem of consciousness. Trained in computer science at Imperial college, he wrote the first version of his Fractal Brain Theory in 2016, in his book of the same name, and it was picked up by quantum consciousness theorist Stuart Hameroff, who invited him to the Science of Consciousness Conference, alongside heavy weights in the field like David Chalmers, Roger Penrose, Sue Blackmore,  Donald Hoffman - many who've been on this show already. This recognition catapulted his theory into the field, so it's with great pleasure that I include it on the show for us to compare alongside the theories of many of the giants. What we discuss: 00:00 Intro 07:10 Symmetry explained: Variance and non-variance; change and resistance to change 11:00 Genomes work like tiny fractal brains 12:30 The symmetry between intelligence and life, neurones and genes 13:00 Junk DNA, neurones and boolean algebra 17:45 Dendritic structure, processing and artificial intelligence 19:00 Self-similarity and recursively nested symmetry 21:30 Evolution and ontogenesis algorithm: differentiate, select, amplify  22:15 Fractal Mathematics and Benoit Mandelbrot: Approximate self-similarity 25:45 Binary trees generating life and intelligence 29:00 Mitosis and progenator fields 30:00 Allocentric and egocentric mapping (Nobel prize) 34:40 Goodwin and cell division VS epigenetic mutation/adaptation 36:00 Recursive modification IS intelligence; evolving evolvability 40:15 A new calculus: analytic geometry  47:00 The soft and hard problem of consciousness  51:00 Time symmetric quantum mechanics and problems with causal chains  58:00 David Chalmers: Identity cosmo-psychism critique 01:11:00 Is self-reflective conscious Ai possible? 01:19:30 Penrose: Quantum mechanics is incomplete until we understand the collapse of the wave function 01:21:00 The ethical debate about the future of Ai References: ‘The Fractal Brain Theory' Wai Tsang Wai Tsang You Tube Channel  Boolean Algebra David Chalmers, “Idealism and the mind body problem” paper

Sami joins James and Amy to discuss Mitosis and talk all about frameworks.Show Notes00:00 Introduction00:40 Welcome Sami01:22 What is Builder.io05:38 More Mitosis13:09 Cross Platform With Swift20:02 Importance of Different Frameworks22:54 Favorite Frameworks25:04 Communities and Libraries 29:27 Opensource Roadmap31:34 Testing33:04 Chat GPT and AI35:43 Behind The Scenes Dev Work40:26 Quality vs Speed46:22 Picks and Plugs

In this supper club episode of Syntax, Wes and Scott talk with Miško Hevery about why developers should check out Qwik, the benefits of lazy loading, sharing state between components, and other Builder.io projects like Partytown and Mitosis. Show Notes 00:35 Welcome 01:19 Guest intro Miško Hevery @MHevery 01:58 What is Resumability? 05:06 What is Qwik? Qwik Qwik City 07:03 Why would you want to make a component resumable? 12:08 Qwik code can be lazy loaded 15:28 How is server side rendering handled? 18:12 How does Vite help? 22:40 A bit more about hydration 31:03 How does the server collection information? 32:11 How do you share state between components? 34:45 How is data fetching handled? 37:47 Why are you using JSX? 41:53 Dealing with components in other frameworks Mitosis 49:21 What is Partytown? Partytown 54:30 Supper Club questions ××× SIIIIICK ××× PIIIICKS ××× Thinking Fast and Slow Shameless Plugs Builder.io Tweet us your tasty treats Scott's Instagram LevelUpTutorials Instagram Wes' Instagram Wes' Twitter Wes' Facebook Scott's Twitter Make sure to include @SyntaxFM in your tweets

Adam Bradley is the Director of Technology at Builder.io and co-creator of Partytown, a lazy-loaded library to help relocate resource intensive scripts off the main thread and into a web worker.In this episode we discuss making sites significantly more performant by offloading third party scripts into a web worker with Partytown, how Partytown fits into the larger suite of tools that Builder.io is working on including Qwik, and cross-compiling any frontend UI library with Mitosis.Adam Bradley Twitter GitHub Partytown Homepage GitHub Links WordPress Partytown Support Add Partytown support to run scripts in WordPress Worker Thread Offloading Scripts To A Web Worker in Next.js (experimental) How to Add Google Analytics gtag to Gatsby Using Partytown How to Deploy the Qwik JavaScript Framework Deploy a Qwik site on Cloudflare Pages Building Marko 6 w/ Dylan Piercey, and Michael Rawlings Resumability, WTF? Show Outline00:12 - Introduction01:26 - Do you miss mobile?04:43 - What is Partytown?07:50 - Can you use Partytown with WordPress?09:42 - How does Google Tag Manager work with Partytown?12:45 - Is there a roadmap for upcoming features or is Partytown feature complete?13:50 - What is Partytown's opinion on shipping no JavaScript?14:39 - How does Partytown fit into the larger suite of tools that Builder.io is working on?16:24 - Qwik as a server-side rendering first framework with QwikCity19:35 - Will it be possible in the future to migrate a Next.js project to QwikCity? 23:07 - Is QwikCity production ready?25:00 - How do you deploy a Qwik or QwikCity application?30:45 - What is Mitosis?34:19 - How does Qwik compare to Solid and Marko?40:09 - Will JavaScript ever reach utopia by attaining the nirvana of PHP?

This week on Baseless Claims we discuss No-Fly-List hackers, the perfect heist, Capri Sun loving aliens, disasterous gender reveals, Tyler's Wahlburger's Related Nighttime Emission, and the creation story of the Blue Man Group. Suggest topics and ask questions for the show here in the comments or over on our Discord! -Socials- Shapeless Media: Twitter.com/ShapelessMedia Tory: http://bit.ly/ToryTwitter Tyler: http://bit.ly/TylerTwitterSG Tay: http://bit.ly/TayTwitter Discord: https://discord.gg/78uGZZYhkz Instagram: instagram.com/ShapelessGaming Baseless Claims Facebook: facebook.com/BaselessClaims TikTok: https://vm.tiktok.com/ZMdDtkUhr/

The "cell cycle" describes discrete steps in the process of cell division.  The progression is mediated by a series of gatekeeping biochemical activities that ensure complete replication of DNA, and surveil it for fidelity. Precise execution of cell cycle is necessary for normal growth and development.  At the same time, loss of cell cycle coordination can lead to aberrant cell proliferation that can become genetically unstable, a condition recognized as cancer. Many drugs target the enzymes that control cell cycle progression, and several appear to be attractive candidates for future therapeutics. Spiro Rombotis of Cyclacel Pharmaceuticals describes targeting the cell cycle, along with new drugs that show promise in slowing, arresting, or possibly reversing some challenging subtypes of cancers. 

In this episode we will discuss mitosis which is the process of cell division for the somatic cells of your body. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

There was an unexpected reward when the vaccine turned out to be polyvalent and worked against several diseases. POLY-. Is that a prefix? No, it's a base, a Greek base, meaning “many, much.” Next element? VAL-, a Latin base meaning “be strong, be worthy.” Last element? The suffix -ent, meaning “-ing,” so this word is what part of speech? An adjective. And what do you think it means? Construct an etymological definition: “being strong (i.e. effective) in many (i.e. multiple) ways,” which implies a vaccine that “counteracts more than one toxin or microorganism.” Be sure, however, that the first word of your definition ends in -ing. This is an adjective: “counteracting more than one toxin…” The real tragedy is that drug use by women in this social class accounts for so many perinatal mortalities. A Greek prefix, peri- (“around, near”). Then what? A Latin base, NAT- (“be born”). And the last element? The suffix -al (“pertaining to”), which means this word is what part of speech? An adjective: “pertaining to being around being born.” The implication is clearly the time of birth. So, what's the definition? Remember to make it an adjective. “Occurring at or around the time of birth.” Con + tempor + ary - “with” + “tempor, temporis” “With the times” (Contemporaneous) Tempo - the speed at which a passage of music is or should be played. (Tempor) Co + habitation = (habito, habitare - “to live/ to live and/or have a home”) Co + labor + ate = to work together Con + solidate = to bring together with (solidatum= to make solid/ bring together) Con + done = give with/together “With” + “gift” Solidarity = support or sympathy “Solidatum” - to make solid/ bring together _________________________________________________________________________________________________________________________________________ Telomere - a compound structure at the end of a chromosome. “telos(end)” + “part” Telophase - the final phase of cell division, between anaphase and interphase, in which the chromatids or chromosomes move to opposite ends of the cell and two nuclei are formed. “End” + “stage” Mitosis - a type of cell division that results in two daughter cells each having the same number and kind of chromosomes as the parent nucleus, typical of ordinary tissue growth. “mitos(thread)” Mitochondria - POWERHOUSE OF THE CELL “Thread” + “kondros(granule)” + “likeness/related to” Chondromalcia patellae (genitive form of Patella) - degeneration of cartilage in the knee, usually caused by excessive wear between the patella and lower end of the femur. “Granule(transitions into - cartilage)” + “soft/softening” Chondrosarcoma - a type of bone cancer that develops in cartilage cells. Cartilage is the specialized, gristly connective tissue that is present in adults and the tissue from which most bones develop. Cartilage plays an important role in the growth process. “Cartilage” + “ flesh/muscle” + “tumor” --- Support this podcast: https://anchor.fm/liam-connerly/support

Brie enters the Morpheus Network, where something dangerous lurks…. Ellis gives a tour. Viola wants a coffee. . Tartarus is a sci-fi horror fiction podcast. An anxious astrobiologist, the terse manager of a secret Antarctic facility, and an A.I, keep humanity safe from the monsters they imprison. . Transcripts: PDF: https://bit.ly/3AzjgM8 Text: https://bit.ly/3e5AtVO . Content warnings: PDF: https://bit.ly/3B5NxDz Text: https://bit.ly/3ALmWdX . Sound Attributions: https://bit.ly/3QJEP35 . Tartarus, Episode 6, Mind Mitosis, was written by Arah Collins, Cam Thatcher, and Kitto Maddrell. Producer and Head Writer, Kitto Maddrell, Producer and Director by Janet Lalla-Hamblin. Brie Lake was voiced by Milly Hall, Ellis by Arah Collins, Viola by Janet Lalla-Hamblin. Dr Santoro and Amalgamate by Helen Stirling-Lane. Miller by Howard Squires. Cultist by Ja'Nya Austin. NPC Waiter by Wyn Turner. Talk Show Host by Gavin Matthew. Dr Hawthorne by Sue King-Spear. Scientist by Celine Shanu. Sigourney by Rebekah McLoughlin. Narrator by Oliver Jupiter Gibb.Sound Editing by Janet Lalla-Hamblin. Theme Music by Russ Evans, 'Badass Boss Battle Music' by Alex Manolache. Story Consultant: Arthur Greenhalf. Logo by Skye-Blue Scott Moon, and Promotional Artwork by Richard Jeffers. This episode used sound effects and music from freesound.org, zapsplat.com, Internet Archive, nixiebunny.com and TrackTribe, full attributions are linked in the episode description. 'Tartarus' created by Kitto Maddrell and Milly Hall. . Follow us: Twitter: twitter.com/tartaruspod Instagram: instagram.com/tartaruspod Tumblr: tartaruspod.tumblr.com . Get in touch at tartaruspod@gmail.com

Tonight Wednesday November 20th 1946 ten thousand snakes whosevenom I summoned leapt into the air across the entire earthWednesday 27 November 1946 at twenty-three hours in the eveningbeings that have not swallowed the nail, but have swallowed the pointFriday 13 December 1946 the espousals of my rondelles,testicular, infantile rondelles, through the palpatory intellectual lips

Con + tempor + ary - “with” + “tempor, temporis” “With the times” (Contemporaneous) Tempo - the speed at which a passage of music is or should be played. (Tempor) Co + habitation = (habito, habitare - “to live/ to live and/or have a home”) Co + labor + ate = to work together Con + solidate = to bring together with (solidatum= to make solid/ bring together) Con + done = give with/together “With” + “gift” Solidarity = support or sympathy “Solidatum” - to make solid/ bring together _______________________________________________________________________ BIO Processes Telomere - a compound structure at the end of a chromosome. “telos(end)” + “part” Telophase - the final phase of cell division, between anaphase and interphase, in which the chromatids or chromosomes move to opposite ends of the cell and two nuclei are formed. “End” + “stage” Mitosis - a type of cell division that results in two daughter cells each having the same number and kind of chromosomes as the parent nucleus, typical of ordinary tissue growth. “mitos(thread)” Mitochondria - POWERHOUSE OF THE CELL “Thread” + “kondros(granule)” + “likeness/related to” Chondromalcia patellae (genitive form of Patella) - degeneration of cartilage in the knee, usually caused by excessive wear between the patella and lower end of the femur. “Granule(transitions into - cartilage)” + “soft/softening” Chondrosarcoma - a type of bone cancer that develops in cartilage cells. Cartilage is the specialized, gristly connective tissue that is present in adults and the tissue from which most bones develop. Cartilage plays an important role in the growth process. “Cartilage” + “ flesh/muscle” + “tumor” ______________________________________________________________________________________________ Legal Nomenclature Jurisprudence - study, theory, or philosophy of law “Juris (from “ius, iuris” = law) + “prudentia(knowledge)” In fact; philosophy = philo(love/lover of) + sophos(wise) And further!!! Sophomore = sophos(wise) + moros(stupid/fool) Jurisdiction - the power, right, or authority to interpret and apply the law a matter that falls within the court's jurisdiction “Law” + “dictio(participle form of “to say” aka ‘saying')” Perjure - willfully tell an untruth when giving evidence to a court; commit perjury. “per(wrong)” + “ius(law)” - to wrong the law Impunity - freedom from punishment “in(not)” + “punire/punitum(to punish)” Subpoena - a writ ordering a person to attend a court. “under/beneath” + “penalty” (of law) Litigation - The process of a lawsuit “litigare/litigatum(to press a lawsuit)” --- Support this podcast: https://anchor.fm/liam-connerly/support

In this episode Kyle and Chris talk about the immediate effects of cutting pornography out of your life. Chris talks out an idea that he's been developing in the form of an image. Kyle explains why women are too emotional to be taken seriously and accuses every Disney movie ever made of being progressive propaganda, Chris pumps the brakes. Jordan Peterson and his very rare terrible takes are called out while addressing how pointless everything Matthew McConaughey said about gun control was. Kyle then closes out the episode all by his lonesome, rambling about nothing in particular because he's not used to doing the podcast by himself.    Enjoy :)

This week we have an exciting episode that peers into the future of the web.Steve Sewell is the CEO of Builder.io, a company that aims to be the Photoshop of building websites. They've built some clever tools come together to render pages insanely fast. join use for this fascinating conversation.

Subscribe Apple | Google | Spotify | Stitcher | iHeart   Support The Daily Gardener Buy Me A Coffee   Connect for FREE! The Friday Newsletter | Daily Gardener Community   Historical Events 1805 Birth of Hugo von Mohl, German botanist.  One newspaper called him the "greatest botanist of his day." He coined the word protoplasm. He discovered Mitosis and chloroplasts - describing them as discrete bodies within the green plant cell in 1837. In 1846 he described the sap in plant cells as "the living substance of the cell" and created the word "protoplasm."   1859 On this day, the Ohio Legislature named Alliance, Ohio, the "Carnation City," saying "truly it is the home of Ohio's State flower," thanks to the work of the amateur horticulturist Levi L. Lamborn (books by this author). In 1876, Levi ran against his friend William McKinley for congress. Before every debate, Levi gave William a "Lamborn Red" Carnation to wear on his lapel. Levi had propagated and named the Lamborn Red Carnation from seedlings he had received from France. After William won the election, he considered the Lamborn Red Carnation his good luck charm - his lucky flower - and he wore a Lamborn Red Carnation during his successful campaigns for Governor of Ohio and President of the United States. William wore a Lamborn Red Carnation when he was sworn into office. He was also wearing one when he attended the Pan-American Exposition in Buffalo, New York, in 1901. At that event, he removed the Carnation and gave it to a 12-year-old girl named Myrtle Ledger, saying, I must give this flower to another little flower. Minutes later, in the receiving line, he greeted his assassin, Leon Czolgosz. President McKinley lingered for eight days after being shot twice before finally succumbing to infection. When McKinley's funeral train passed through Alliance, Ohio, the train tracks were covered in Lamborn Red Carnations.  The Ohio General Assembly named the scarlet Carnation the official Ohio floral emblem three years later. The resolution reads: Even though the first mention of the Dianthus genus of plant... is traced to some four hundred years before the birth of Christ, it was not until a native son of Alliance, Ohio, (Levi L. Lamborn) worked his floricultural magic that it blossomed as the matchless symbol of life and love that is today. Representative Elijah W. Hill, from Columbiana County, said, England has the rose, France has the lily; Ireland, the shamrock; Scotland, the thistle. ...To these ends, we seek to adopt the scarlet Carnation as Ohio's floral emblem. Fifty-five years later, on this day, April 8, 1959, Alliance, Ohio, became the "Carnation City" thanks to the work of Levi L. Lamborn. Every year since 1960, Alliance has held a Carnation festival. In 2022, the 10-day festival takes place between August 4 - August 14.   1892 Birth of Mary Pickford (books about this person), born Gladys Marie Smith, became known as America's sweetheart and a Hollywood legend. Mary was also a lover of trees. If you jump on Twitter, search for "Mary Pickford Tree," and you'll see images of Douglas Fairbanks and Mary Pickford planting a tree at their PickFair estate. #ArborDay Mary Pickford was the first to plant a Japanese cedar tree in the Forest of Fame at the California Botanic Garden. And Trivia/Folklore says that Mary Pickford used to eat flowers - especially roses. Katie Melua sang about Mary in a song that goes: Mary Pickford Used to eat roses Thinking they'd make her Beautiful, and they did-  One supposes. In real life, Mary did indeed eat roses. Mary Pickford revealed in her autobiography, Sunshine and Shadow that as a young girl living in Toronto, she would buy a single rose and eat the petals, believing the beauty, color, and perfume would somehow get inside her. Mary starred in Madame Butterfly (1915). The movie was shot in the Japanese garden of Charles Pfizer's Bernardsville, New Jersey estate called Yademos, the word "someday" spelled backward. The elaborate three-and-a-half-acre Japanese garden - complete with a lake filled with Japanese goldfish, a tea house, and a hooped and arched bridge - looked like it had been there forever - but in reality, the garden was only nine years old.    1918 Birth of First Lady Betty Ford (books about this person). As a woman, Betty Ford consistently defied the odds. She was an incredible trailblazer and very open about her struggles with alcohol and breast cancer. She revolutionized addiction treatment and opened her center for treatment while she was in the middle of working on her own recovery. Today' the Betty Ford Alpine Gardens is a fitting living tribute to this remarkable woman. Known as Vail's Alpine Treasure, the garden was founded in 1985 by the Vail Alpine Garden Foundation and renamed in honor of Betty three years later in 1988. This special place is located in Ford Park right next to the Gerald R. Ford Amphitheater–named in honor of her husband, the 38th president of the United States. Over the years, the Betty Ford Alpine Garden has evolved to comprise four distinct sections; Mountain Perennial Garden (1989), Mountain Meditation Garden (1991), Alpine Rock Garden (1999), & the Children's Garden (2002.) Today, over 3,000 species of high-altitude plants play host to children's programs, horticultural therapy activities, and numerous partnerships and conservation initiatives. In 1991, Betty said, When I was a little girl, I spent many cherished hours with my mother in her garden. She wisely marked off an area for my very own plants. As we worked together, she nurtured me as she nurtured my love of gardening. This nurturing mother-daughter relationship, with its love growing strong in a garden, has been passed along to my daughter, Susan, and her two girls.   Grow That Garden Library™ Book Recommendation Immersion by Nola Anderson  This book came out on April 13, 2021 - (so we're almost at the year anniversary) - and the subtitle is Living and Learning in an Olmsted Garden. This book came about because Nola Anderson and her husband purchased a property called The Chimneys in 1991. The Chimneys was an old estate, and  Frederick Law Olmsted Jr. designed the gardens for the original owners. Sadly, the property had fallen into ruin by the time Nola and her husband got ahold of it. The Chimneys story reminds me so much of Sissinghurst. I love when people revive old spaces like this. One of the things that I appreciate about Nola is her courage and curiosity. When Nola walked onto The Chimneys property, she had not a lick of garden experience, which always reminds me of the saying, "Ignorance is bliss." Perhaps if Nola had been a gardener, she might've looked at the property and felt daunted by the task of restoration. But instead, Nola and her husband committed to renewing this incredible seaside garden. After three decades of hard work and research, The Chimneys was a sight to behold.  Originally, The Chimneys was created at the turn of the century, between 1902 and 1914. The Chimneys was home to a wealthy Boston finance guy named Gardiner Martin Lane and his wife, Emma. They hired Frederick Law Olmsted Jr. to create an Italianate garden for them. The seaside garden is perched on a bluff and comprises a series of garden terraces that gradually taper down with the natural topography. The very top terrace is called the water terrace and features a rose-covered pergola and a shelter that boasts a stunning view of the terraces below and the ocean. Then there is the most incredible water feature (on the book cover), inspired by a 16th-century country estate in Italy called Villa Lante. In the Facebook group for the show, I shared a video of Monte Don walking through the incredible garden at Villa Lante. Monte says that this garden, Villa Lante, is the prime example of an Italianate Garden and the inspiration for Frederick Law Olmsted Jr. when working for the Lane family. The other terraces at The Chimneys are also stunning. They include the overlook terrace, the lavender terrace, the all-white tea terrace, the vegetable garden, the crab apple allee, and finally, the luxuriant rose garden.  So how lucky are Nola and her husband to stumble on The Chimney's estate and then bring it back to life? It really was the chance of a lifetime. And, don't you just love stories like this? The people who take on these forgotten gems - these gardens from our past - usher them through a transformation to reclaim their former glory. Before I forget, I wanted to mention that Clint Clemens is the photographer for this book, and he did a truly magnificent job. The photography is absolutely stunning. This book is 293 pages of The Chimneys - a garden on my bucket list.  You can get a copy of Immersion by Nola Anderson and support the show using the Amazon link in today's show notes for about $50.   Botanic Spark 1955 Birth of Barbara Kingsolver (books by this author), American writer and poet. A daughter of Kentucky, Barbara graduated from DePauw University and the University of Arizona. She worked as a freelance writer before writing novels. Since 1993, her books have made the New York Times Best Seller list. The Poisonwood Bible (1998) brought critical acclaim and told the tale of a missionary family in the Congo - a place Barbara knew briefly as a child when her parents worked in public health in the Congo. In 2007 Barbara shared her family's quest to eat locally in Animal, Vegetable, Miracle, where she wrote, Spring is made of solid, fourteen-karat gratitude, the reward for the long wait. Every religious tradition from the northern hemisphere honors some form of April hallelujah, for this is the season of exquisite redemption, a slam-bang return to joy after a season of cold second thoughts. She also mused, I have seen women looking at jewelry ads with a misty eye and one hand resting on the heart, and I only know what they're feeling because that's how I read the seed catalogs in January.   Thanks for listening to The Daily Gardener And remember: For a happy, healthy life, garden every day.

Check out Noeo Science for your homeschooling needs: https://noeoscience.com/ 

Aliens are one thing, but what about when the alien is the environment and instead of your standard abduction it wanted to change you from the inside out? THIS is the horror of Annihilation; the notion that something would take us and make us into something new. It's not even clear if this alien wanting is something evil - what if, like everything else, humanity should die to make room for the next evolution? These are the heady questions Meg and Kris grapple with as they step into the Shimmer with the ladies of ANNIHILATION (2018). It's truly the invasion of the atom snatchers! Created & Hosted By: Meghan Livingston and Kristin Maccarrone Produced and Edited By: Denis Livingston Music By: Denis Livingston Artwork By: Grace Hughes – follow Grace on Instagram @gmhxedh Follow the Show on Instagram @thenightlightpodcast Email the Show at thenightlightpodcast@gmail.com

#ReckonersSpoilers The Reckoners discussion continues! The SICS crew has moved on to Firefight and the Reckoners have moved on to Babilar, the waterlogged remains of Manhattan. (After a brief encounter with Mitosis, a powerful new Epic.) What is Regalia planning? Who is the mysterious Dawnslight? And what has Firefight been up to since the end of Book 1? ___ This episode's show notes can be found here: https://docs.google.com/document/d/1BqTMIYLgF6q-6G2QFceEP0eKdlboJOBiO2w4ZeLbfhQ/edit?usp=sharing ___ You can support The Sandersonian Institute of Cosmere Studies by becoming a Patron at http://www.patreon.com/cosmerestudies SICS patrons make the show possible and gain access to additional content and early access to bonus episodes. ___ You can email us your questions about the Cosmere at cosmerestudies@gmail.com. We will occasionally select emails to respond to during the show, so we'd love to hear any theories you have, no matter how far-fetched, or anything else you may have to say about Brandon Sanderson's work. ___ Follow us at www.twitch.tv/innkeeperstable for our live shows, which stream on Mondays, every two weeks, at 8:30pm Mountain Time. VODs will be posted on the Cosmere Studies YouTube account here at https://www.youtube.com/cosmerestudies. ___ We'd like to thank the following artists for granting us permission to use their artwork in our opening video. Be sure to check out their websites! Stephan Martiniere - Elantris - http://www.martiniere.com/ Sam Weber - The Mistborn Trilogy - http://www.sampaints.com/ Chris McGrath - Alloy of Law - http://www.christianmcgrath.com/ Dan dos Santos - Warbreaker - http://www.dandossantos.com/ Michael Whelan - Words of Radiance and Oathbringer - http://www.michaelwhelan.com/ David Palumbo - Arcanum Unbounded - http://www.dvpalumbo.com/ ___ The Sandersonian Institute of Cosmere Studies is a biweekly podcast for fans of Brandon Sanderson's Cosmere novels. Bill, Amy, and Jordan discuss Brandon's work and dive a bit too deep into theories and speculation. So put on your aluminum foil hats and join us for the ride as we discuss Brandon's work and your emails, and remember—there's ALWAYS another secret! ___ Write to us! The Sandersonian Institute of Cosmere StudiesPO Box 970063Orem, UT 84097 ___ Find SICS online: Twitch: http://www.twitch.tv/innkeeperstable Youtube: https://www.youtube.com/cosmerestudies Patreon: http://www.patreon.com/cosmerestudies Twitter: http://www.twitter.com/cosmerestudies Facebook: http://www.facebook.com/cosmerestudies Instagram: http://www.instagram.com/cosmerestudies

My AP Biology Thoughts  Unit 5 HeredityWelcome to My AP Biology Thoughts podcast, my name is Nidhi and I am your host for episode # 97 called Unit 5 Heredity: Meiosis. Today we will be discussing what meiosis is, why it's important, and how it connects to other topics we've learned about this year.  Segment 1: Introduction to why Meiosis is important From what we have learned this year, we know Mitosis is used to prudence daughter cells that are genetically identical to a parent cell. On the other hand, the function of meiosis is to produce gametes. The daughter cells have half as many chromosomes as the parent. To put it in other words, a diploid cell is the parent to 4 haploid cells. In humans, the haploid cells produced are sperm and egg cells, essential for reproduction to occur. It imporant that meiosis occurs to produce sex cells and not mitosis because the combiation of 2 cells both with the nomral number of chromosomes during fertiliztion would result in an offspring wth double the normal number of chromosomes. Meiosis also created 4 unique haploid cells unlike mitosis which creates identical daughter cells. Meiosis creates new combinations of genetic material in each of the four daughter cells. The gametes produced through meiosis exhibit a larger range of genetic variation and this allows for genetic variation in a population. This genetic variation is increased even more when the two gametes unite during sexual reproduction. This overall helps to increase diversity in a population which increases the chances of the population surviving in a changing environment. Another difference between Meiosis and Mitosis is that Meiosis involves two rounds of nuclear division. The other events of Meiosis are pretty similar to Mitosis but there are some key differences.  Segment 2: More About what meiosis is To begin, a cell will first go through interphase where the cell grows during the G_1 phase, replicates its DNA during the S phase, and prepares for division during the G_2 phase. Then the cell enters Meiosis 1. It begins in prophase 1 where the chromosomes begin to condense. Unlike mitosis, the condensed chromosomes begin to pair up with their homologous partner. The DNA is then broken at the same spot on each chromosome and the homologous chromosomes exchange part of their DNA in a process called crossing over. This process of crossing over increases genetic variation producing unique chromosomes. After crossing over, the spindle fibers capture the chromosomes and move them towards the center of the cell. THis is similar to how the chromosomes in mitosis are moved by spindle fibers, but in meiosis, homologous pairs—not individual chromosomes—line up at the metaphase plate for separation. The orientation of each pair is random and this allows for the formation of gametes with different sets of chromosomes. In anaphase I, the homologues are pulled apart and move apart to opposite ends of the cell. The sister chromatids of each chromosome, however, remain attached to one another and don't come apart. Finally, in telophase I, the chromosomes arrive at opposite poles of the cell and cytokinesis occurs separating the two haploid daughter cells. After meiosis one, the cell does not re enter interphase to grow like it did before meiosis 1. The daughter cells produced by meiosis 1 enter meiosis 2. These cells are haploid but their chromosomes still consist of two sister chromatids. In meiosis II, the sister chromatids separate, making haploid cells with non-duplicated chromosomes. As part of prophase II, chromosomes condense and the nuclear envelope, if it was present, breaks down. The spindle forms between the speratedd centrosomes, and the spindle microtubules begin to capture chromosomes. The two sister chromatids of each chromosome are captured by fibers from opposite spindle poles. In metaphase II, the chromosomes line up individually along the metaphase plate. In anaphase II, the sister...