Podcasts about adipose

Join Joe, Frazer, Daniel & Kieran as we face Adipose, Pyrovilles, evil corporations, Sontarans and genetic warfare in the aim to crown the winner of this half season...with a very special guest star!

Cyrus Khambatta reveals how a plant-based diet can reverse prediabetes and type 2 diabetes. Learn the science and practical steps to take control of your health. #ReverseDiabetes #PlantBasedDiet #HealthyLiving

Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Jordi Mayneris-Perxachs and Dr Anna Castells-Nobau from the Girona Biomedical Research Centre (IDIBGI), Girona, Spain, on the paper "Multiomics of the intestine-liver-adipose axis in multiple studies unveils a consistent link of the gut microbiota and the antiviral response with systemic glucose metabolism" published in paper copy in Gut in February 2025. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).  

In this episode of the Epigenetics Podcast, we talked with Ferdinand von Meyenn from ETH Zürich about his work on the interplay of nutrition, metabolic pathways, and epigenetic regulation. To start Dr. Meyenn recounts his pivotal research on DNA methylation in naive embryonic stem cells during his time with Wolf Reick. He explains the dynamics of global demethylation in naive stem cells, revealing the key enzymes involved and the unexpected findings surrounding UHF1—its role in maintaining DNA methylation levels and influencing the methylation landscape during early embryonic development. Dr. Meyenn then shares his perspective on the scientific transition to establishing his own lab at ETH. He reflects on his ambitions to merge the fields of metabolism and epigenetics, which is a recurring theme throughout his research. By investigating the interplay between metabolic changes and epigenetic regulation, he aims to uncover how environmental factors affect cellular dynamics across various tissues. This leads to a discussion of his recent findings on histone lactylation and its implications in cellular metabolism, as well as the intricacies of epigenetic imprinting in stem cell biology. Last but not least we touch upon Dr. Meyenn's most recent study, published in Nature, investigating the epigenetic effects of obesity. He provides a detailed overview of how adipose tissue undergoes transcriptional and epigenetic rearrangements during weight fluctuations. The conversation highlights the notion of epigenetic memory in adipocytes, showing how obesity is not just a temporary state but leaves lasting cellular changes that can predispose individuals to future weight regain after dieting. This exploration opens avenues for potential therapeutic interventions aimed at reversing adverse epigenetic modifications.   References von Meyenn, F., Iurlaro, M., Habibi, E., Liu, N. Q., Salehzadeh-Yazdi, A., Santos, F., Petrini, E., Milagre, I., Yu, M., Xie, Z., Kroeze, L. I., Nesterova, T. B., Jansen, J. H., Xie, H., He, C., Reik, W., & Stunnenberg, H. G. (2016). Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells. Molecular cell, 62(6), 848–861. https://doi.org/10.1016/j.molcel.2016.04.025 Galle, E., Wong, C. W., Ghosh, A., Desgeorges, T., Melrose, K., Hinte, L. C., Castellano-Castillo, D., Engl, M., de Sousa, J. A., Ruiz-Ojeda, F. J., De Bock, K., Ruiz, J. R., & von Meyenn, F. (2022). H3K18 lactylation marks tissue-specific active enhancers. Genome biology, 23(1), 207. https://doi.org/10.1186/s13059-022-02775-y Agostinho de Sousa, J., Wong, C. W., Dunkel, I., Owens, T., Voigt, P., Hodgson, A., Baker, D., Schulz, E. G., Reik, W., Smith, A., Rostovskaya, M., & von Meyenn, F. (2023). Epigenetic dynamics during capacitation of naïve human pluripotent stem cells. Science advances, 9(39), eadg1936. https://doi.org/10.1126/sciadv.adg1936 Bonder, M. J., Clark, S. J., Krueger, F., Luo, S., Agostinho de Sousa, J., Hashtroud, A. M., Stubbs, T. M., Stark, A. K., Rulands, S., Stegle, O., Reik, W., & von Meyenn, F. (2024). scEpiAge: an age predictor highlighting single-cell ageing heterogeneity in mouse blood. Nature communications, 15(1), 7567. https://doi.org/10.1038/s41467-024-51833-5 Hinte, L. C., Castellano-Castillo, D., Ghosh, A., Melrose, K., Gasser, E., Noé, F., Massier, L., Dong, H., Sun, W., Hoffmann, A., Wolfrum, C., Rydén, M., Mejhert, N., Blüher, M., & von Meyenn, F. (2024). Adipose tissue retains an epigenetic memory of obesity after weight loss. Nature, 636(8042), 457–465. https://doi.org/10.1038/s41586-024-08165-7   Related Episodes Nutriepigenetics: The Effects of Diet on Behavior (Monica Dus) Epigenetic and Metabolic Regulation of Early Development (Jan Żylicz) Effects of Environmental Cues on the Epigenome and Longevity (Paul Shiels)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Why do people regain weight more quickly than expected after successfully losing it? Research shows that once someone has been overweight or obese, the genes in their fat cells undergo changes, creating a "memory" of the overweight state. This makes it easier for the body to return to that state. Listen in this week as Dee discusses this fascinating research, and what it means for long term weight loss maintenance.Reference:Hinte, L. C., Castellano-Castillo, D., Ghosh, A., Melrose, K., Gasser, E., Noé, F., Massier, L., Dong, H., Sun, W., Hoffmann, A., Wolfrum, C., Rydén, M., Mejhert, N., Blüher, M., & Von Meyenn, F. (2024). Adipose tissue retains an epigenetic memory of obesity after weight loss. Nature, (2024). https://www.nature.com/articles/s41586-024-08165-7

Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us. I recently tuned into a podcast with Jillian Michaels—the trainer from The Biggest Loser (possibly one of the most problematic shows to ever grace TV). I listened as she doubled down on the same old narrative: weight loss is all about motivation, eating less, and moving more. It was frustrating, especially because two respected physicians in the obesity medicine community were trying to bring a more evidence-based approach to the conversation, but it was falling on deaf ears.As research continues to reveal, chronic obesity is a complex condition that differs significantly from simple weight management. It's clear that it's time to move beyond these outdated beliefs and focus on the science shaping our understanding of obesity today. In this episode, we'll explore the latest scientific research on obesity, including how metabolic and hormonal responses to weight loss differ for those with chronic obesity, as well as the benefits of GLP-1s and GIPs that go far beyond weight loss alone.ReferencesHinte, L.C., Castellano-Castillo, D., Ghosh, A. et al. Adipose tissue retains an epigenetic memory of obesity after weight loss. Nature (2024).Audio Stamps02:38 - Dr. Rentea critiques Jillian Michaels' outdated stance on obesity as a chronic condition, and emphasizes the importance of evolving with current science in understanding obesity and its treatments.07:56 - Dr. Rentea discusses the growing body of evidence showing that GLP-1 medications offer numerous health benefits beyond weight loss, including improvements in various metabolic and cardiovascular conditions.10:49 - We learn how GLP-1 medications help protect the cardiac system by improving endothelial function, reducing blood pressure, and lowering inflammation and cholesterol.13:20 - It's becoming increasingly difficult to ignore the wide-ranging health improvements these medications offer beyond just weight loss.Quotes“I believe radically different right now than what I did five, six years ago. Every single year I'm learning new things.”“The biggest question I always get asked from people is, ‘When I lose the weight, am I good? Can I then just go on with my life?' and I always say, ‘It's a chronic medical condition, meaning it's there for life. We can manage it, we don't have a cure.'”“It's been an explosion recently of updates from long term trials and new trials that are showing ever increasing benefits of GLP-1s and GIPs.”“It's never been about shapeshifting. It's never been about what size you are. It's really always about health. And this is a hard shift because most people are just obsessed with what the scale number is.”All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast. If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com

Piscine doomsday, Native democracy, Racecar rats, Superbug soldiers, Gopher rejuvenation, Asteroid contamination, Adipose memory. Jennifer, Angie, Way, and Bradley discuss the curated links for the week of 11/29/2024. Please consider supporting this ad-free content on Patreon.

One should know that type 2 DM is not only caused by beta cell dysfunction of pancreas. There are eight different organs of body involved in the pathophysiology of T2 DM. 1. Beta cells of pancreas, that they don't produce enough insulin. 2. Alpha cells of pancreas produce disproportionately high glucagon as there is poor suppression of glucagon in the post meal phase, causing post prandial hyperglycemia. 3. Liver produces extra glucose causing high fasting blood glucose. 4. Skeletal muscles have poor uptake of glucose, which increases blood glucose. 5. Adipose tissue produces higher fatty acid. 6. Incretin hormone from intestine also show dysregulation (GLPl & GIP) 7. Kidney increase glucose reabsorption from proximal convoluted tubules 8. Brains satiety centers show dysregulation. 9. Thus, while treating a case of T2 DM, we should address all Eight Arms of, So called “Ominous Octet”. Recorded at Akashwani Nagpur on the 30th August 2024 Anchor – Kalyani Gokhale Speaker – Dr. Sunil Gupta

In this episode, Dr. Rohrich discusses the power of adipose matrix in facial rejuvenation as opposed to fillers.

ReferencesChitnis MM, Yuen JS, Protheroe AS, et al. The type 1 insulin-like growth factor receptor pathway.Clin Cancer Res 2008,14:6364-6370.Werner H, Bruchim I. The insulin-like growth factor-I receptor as an oncogene.Arch Physiol Biochem 2009, 115:58-71.Davies M, Gupta S, Goldspink G, Winslet M. The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence.Int J Colorectal Dis 2006, 21:201-208.Sandhu MS, Dunger DB, Giovannucci EL. Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer.J Natl Cancer Inst 2002, 94:972-980.Kaaks R. Nutrition, insulin, IGF-1 metabolism and cancer risk: a summary of epidemiological evidence.Novartis Found Symp 2004, 262:247-260; discussion 260-268.Lamberts SW, van den Beld AW, van der Lely AJ. The endocrinology of aging.Science 1997, 278:419-424.Doi T, Shimada H, Makizako H, et al. Association of insulin-like growth factor-1 with mild cognitive impairment and slow gait speed.Neurobiol Aging 2015, 36:942-947.Calvo D, Gunstad J, Miller LA, et al. Higher serum insulin-like growth factor-1 is associated with better cognitive performance in persons with mild cognitive impairment.Psychogeriatrics 2013, 13:170-174.Thissen JP, Ketelslegers JM, Underwood LE. Nutritional regulation of the insulin-like growth factors.Endocr Rev 1994,15:80-101.Clemmons DR, Seek MM, Underwood LE. Supplemental essential amino acids augment the somatomedin-C/insulin-like growth factor I response to refeeding after fasting.Metabolism 1985, 34:391-395.Runchey SS, Pollak MN, Valsta LM, et al. Glycemic load effect on fasting and post-prandial serum glucose, insulin, IGF-1 and IGFBP-3 in a randomized, controlled feeding study.Eur J Clin Nutr 2012, 66:1146-1152.Brand-Miller JC, Liu V, Petocz P, Baxter RC. The glycemic index of foods influences postprandial insulin-like growth factor-binding protein responses in lean young subjects.Am J Clin Nutr 2005, 82:350-354.Biddinger SB, Ludwig DS. The insulin-like growth factor axis: a potential link between glycemic index and cancer.Am J Clin Nutr 2005, 82:277-278.Burgers AM, Biermasz NR, Schoones JW, et al. Meta-analysis and dose-response metaregression: circulating insulin-like growth factor I (IGF-I) and mortality.J Clin Endocrinol Metab 2011, 96:2912-2920.Ranke MB, Osterziel KJ, Schweizer R, et al. Reference levels of insulin-like growth factor I in the serum of healthy adults: comparison of four immunoassays.Clin Chem Lab Med 2003, 41:1329-1334.Bidlingmaier M, Friedrich N, Emeny RT, et al. Reference intervals for insulin-like growth factor-1 (igf-i) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-I immunoassay conforming to recent international recommendations.J Clin Endocrinol Metab 2014, 99:1712-1721.Brabant G, von zur Muhlen A, Wuster C, et al. Serum insulin-like growth factor I reference values for an automated chemiluminescence immunoassay system: results from a multicenter study.Horm Res 2003, 60:53-60.Crowe FL, Key TJ, Allen NE, et al. The association between diet and serum concentrations of IGF-I, IGFBP-1, IGFBP-2, and IGFBP-3 in the European Prospective Investigation into Cancer and Nutrition.Cancer Epidemiol Biomarkers Prev 2009,18:1333-1340.Fontana L, Klein S, Holloszy JO. Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk.Am J Clin Nutr 2006, 84:1456-1462.Fontana L, Weiss EP, Villareal DT, et al. Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans.Aging Cell 2008, 7:681-687.Friedrich N, Haring R, Nauck M, et al. Mortality and serum insulin-like growth factor (IGF)-I and IGF binding protein 3 concentrations.J Clin Endocrinol Metab 2009, 94:1732-1739.Carlzon D, Svensson J, Petzold M, et al. Both low and high serum IGF-1 levels associate with increased risk of cardiovascular events in elderly men.J Clin Endocrinol Metab 2014, 99:E2308-2316.Svensson J, Carlzon D, Petzold M, et al. Both low and high serum IGF-I levels associate with cancer mortality in older men.J Clin Endocrinol Metab 2012, 97:4623-4630. .van Bunderen CC, van Nieuwpoort IC, van Schoor NM, et al. The Association of Serum Insulin-Like Growth Factor-I with Mortality, Cardiovascular Disease, and Cancer in the Elderly: A Population-Based Study.J Clin Endocrinol Metab 2010.Arai Y, Takayama M, Gondo Y, et al. Adipose endocrine function, insulin-like growth factor-1 axis, and exceptional survival beyond 100 years of age.J Gerontol A Biol Sci Med Sci 2008, 63:1209-1218.Johnsen SP, Hundborg HH, Sorensen HT, et al. Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke.J Clin Endocrinol Metab 2005, 90:5937-5941.Hankinson SE, Willett WC, Colditz GA, et al. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer.Lancet 1998, 351:1393-1396.Chan JM, Stampfer MJ, Giovannucci E, et al. Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study.Science 1998, 279:563-566.

References Nat Commun. 2022; 13: Article Number:6661. Nature Commun. 2024; 15: Article number:1541 Myrow and Gordon 1946. You Make Me Feel so Young. Sinatra https://open.spotify.com/track/6N1amIkGGddramWRDrP3Nm?si=0de15d2fec054455 Mozart WA. 1773 Symphony 24 in G minor. K.183 https://youtu.be/707oHEGF6l8?si=E_1zWSSN5zRAHs9i --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Guerra, DJ. 2024. lecture notes Leach, Donovan. 1967 "Mountain Jam" Allman Brothers https://youtu.be/w9ZubobGMLs?si=uHLon1CvCiCSiqtX --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

In this episode, we talk about brown fat and some new discoveries in how it regulates metabolic function. Joining host Aaron Lohr is Marsel Lino, PhD, a research fellow at Joslin Diabetes Center in Boston. Dr. Lino presented an abstract at ENDO 2024 titled, “A New Layer of Endocrine Regulation: Brown Fat Secretes Exosomal MicroRNAs, Which Regulate Metabolic Functions and Distal Organs.” Show notes are available at https://www.endocrine.org/podcast/enp89-brown-fat-and-metabolic-function — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

In this special episode of The Dr. Tyna Show, I'm tackling the puzzling phenomenon of midlife weight gain—a challenge many of us women face. If you've noticed your midsection thickening and overall body changes as you hit middle age, you're definitely not alone. I'll break down a recent study on this topic, covering metabolic dysfunction, the role of estrogen, and the impact of physical activity. Join me as I explore the complexities of this stage of life and offer practical solutions, including the benefits of exercise and resistance training. Tune in to uncover the science and get actionable insights for managing your health during this transformative period and learn WHY I think microdosing GLP1 agonists can be such a potent tool in this struggle. On This Episode We Cover: 02:04 - Summarizing the study  07:01 - Metabolic dysfunction in middle aged women  10:03 - The importance of physical activity 11:47 - Disease risk and metabolic syndrome  15:03 - Estrogen, appetite, and physical activity  19:25 - GLP1s, reward pathways, and movement 22:05 - Insulin resistance, mitochondrial and immune dysfunction   25:13 - Testosterone and estrogen rations 26:54 - Adipose tissue dysfunction  28:51 - Obesity, inflammation, and pain  30:11 - Weight affects people differently  33:36 - Therapeutic effects of exercise 35:21 - Insulin resistance 37:43 - The importance of resistance training, HIIT, and yoga  41:52 - Sleep and hormones  44:35 - Study conclusions Sponsored By: BIOptimizers Go to masszymes.com/drtynafree for your first free bottle of Masszymes Maui Nui Use code DRTYNA for 20% off at mauinuivenison.com Show Links: Adipocyte Metabolism and Health after the Menopause: The Role of Exercise Ozempic Done Right University Coupon Code: OUVIP Further Listening EP. 94: For the Men: Master Your Testosterone | Solo Episode EP. 95: Women Need Testosterone, Too | Solo Episode EP. 104: Fatty Liver 101 | Solo Episode EP 106: Ozempic Done Right Part 1 | Solo Episode EP 107: Ozempic Done Right Part 2 | Solo Episode EP. 109: Ozempic Done Right Part 3 | Solo Episode EP. 129: Ozempic Done Right Part 4: Sustained Weight Loss | Solo Episode EP. 132: Ozempic Done Right Part 5: Osteoarthritis + GLP1 Agonists | Solo Episode Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

Clayton from 'Men Who Like Men Who Like Movies' joins Sean for a brand new side-series. The Donna Noble Chronicles will explore every episode from 2006-2010 which starred Catherine Tate as Donna, from 'The Runaway Bride' to 'The End of Time'. This second episode explores the Series Four opener: Partners in Crime. Discussion Points: -The characterisation of Donna Noble in this episode. -The quality of this episode. -Clayton thinks Tennant and Tate are the ultimate duo, ever. Sean thinks he is being silly. -The power of a Health and Safety badge. -The performance of Sarah Lancashire. -The noise of the Adipose. -*Lance not Lawrence. -Sean introduces Clayton to the word 'ginnel'. -The fantastic moment where the Doctor looks up and realises that he is alone in the TARDIS. -Clayton isn't a fan of The Voyage of the Damned. -The iconic reunion scene and the brilliant ending scene with Wilf. Raised Questions: -Did they soften Donna in this re-introductory episode? -Are all New-Who companions in love with the Doctor? -Is this episode better than you remember? -How many floors does that building have? -Has this episode become more topical? -Did you pick up on the 'Super-Nanny' look of Miss Foster? -Does anyone want a podcast concerned with Data Protection? -Do you miss the moments when the Doctor goes into the darker side of his character? -Is it plausible to hide in a toilet cubicle for 6 hours? -Which scene did they leave out of the press screening? Thanks for Listening! Review It Yourself is now on YouTube! Find us here: Twitter: @YourselfReview Instagram: reviewityourselfpodcast2021 YouTube: https://www.youtube.com/@ReviewItYourself⁠ This podcast is a member of the PodPack Collective, an indie podcasting group dedicated to spreading positivity within the podcast community. For further information, please follow the link: https://linktr.ee/podpackcollective

Exploring the phenomenal range of roles estrogens play with respect to our metabolism – a range that is only just beginning to be understood. With Deborah Clegg, Texas Tech University

Over the years, stem cells have gained significant attention for their remarkable ability to transform into various cell types, presenting immense potential for regenerative medicine and treatment for a wide range of diseases. This growing interest has been driven by a series of groundbreaking discoveries and significant advancements in stem cell research. In the context of breast implants and breast implant illness, stem cells offer promising solutions for tissue regeneration and recovery, providing new hope for those seeking alternative treatments. Whether you're curious about the science behind stem cells or considering a procedure involving fat transfer, this episode is packed with valuable insights to guide you on your journey to better health and wellness. Let's explore more about how stem cells are transforming the medical field, providing new avenues for treatment and recovery. We'll dive into valuable insights and the latest advancements, helping you understand the incredible potential of stem cells and their benefits. Fat transfer surgery for breast augmentation and reconstruction I've recently attended several notable conferences where I gained valuable insights and innovations that I'm eager to integrate into our clinic. Some of these advancements include the incorporation of more lymphatic massage techniques, the introduction of NanoVi technology to improve protein folding and recovery, and the use of H-Wave therapy to further enhance lymphatic drainage and aid in patient recovery. For today, however, let's focus on fat transfers. Drawing from my extensive experience with fat transfers, a technique I've refined over many years, I explain that fat transfers are effective because they use the patient's own tissue, making them autologous and thus free from the risks associated with donor tissues, such as genetic mismatches. Fat transfers are versatile, as adipose-derived stem cells can differentiate into fat cells, bone cells, or cartilage, providing a range of benefits. My initial interest in this technique stemmed from a personal desire to regenerate cartilage in my knees after multiple surgeries, leading to a deep understanding of the procedure's potential. With extensive experience in sarcoma reconstruction, I can confidently say that fat transfers are safe when performed correctly. It's essential not to transfer fat to areas with existing tumors or sarcomas, as these mesenchymal regions could complicate the procedure. For breast augmentation and reconstruction, fat transfers have been effective for many years, and I have conducted numerous procedures since 2005. Successful outcomes depend on transferring a mixture of adipocytes, vascular cells, and adipose-derived stem cells. This technique requires precise placement of fat in specific areas to avoid complications and ensure proper integration with the surrounding tissue. There were early safety concerns regarding fat transfers for cosmetic purposes, such as buttock augmentation, due to technical issues when the procedure first gained popularity in South America and Miami. However, with advancements in techniques and improved safety measures, fat transfers for both buttock and breast augmentation have become reliable and effective procedures. Fat transfer for breast implant illness, including stem cells and healing When the skin gets really tense, you'll notice a condition called "peau d'orange," where the surface of the skin starts to look like the surface of an orange. This indicates too much pressure and that expansion should stop. Unlike implants, which can hold their shape and maintain more volume, fat cannot be continuously added. The amount of fat that can be added depends on the initial condition of the skin. For younger clients with tight skin, multiple sessions may be needed to gradually increase volume. In cases where I remove implants that have been in place for a long time, often after weight changes, pregnancies, or breastfeeding, the skin is usually stretched out. After removing the implant with its capsular material intact, I don't fill the old implant pocket and instead, place the fat beneath the skin, where it belongs, and let it heal. Adipose-derived stem cells in the fat offer numerous benefits, aiding in wound rejuvenation and healing. They can help turn genes on, produce exosomes, modulate immune responses, and improve mitochondrial function. This is why fat transfers are more than just about the fat itself – they bring substantial healing properties. To maintain the results over time, factors like diet, detoxification ability, and gut health are crucial. We strongly advocate for fat transfers, leveraging the healing power of stem cells. We also offer stem cell harvesting and banking, a process I personally undergo every three to six months. Using our cell surgical device and extensive experience since 1998, we continually strive to enhance our offerings and improve patient outcomes. We offer a variety of wellness products and supplies to help you on your recovery journey. So make sure to check out our online store at https://drrobssolutions.myshopify.com/ for extra resources and support. Browse our collection today to find everything you need for a healthier, more vibrant you! Links and Resurces Dr. Robert Whitfield's Website (https://drrobssolutions.com/) For any inquiries or concerns, feel free to connect with us on Instagram (@breastimplantillnessexpert). https://www.instagram.com/drrobertwhitfield/ For more information on Virtual and In Person Consultations, we always answer our messenger personally: https://www.drrobertwhitfield.com/contact/ Try the Echo Hydrogen Water Bottle (https://echowater.com/?oid=21&affid=720) Code is DRROB10. About Dr. Rob Dr. Robert Whitfield (https://www.drrobertwhitfield.com/dr-whitfield-2/) In 2012, Dr. Whitfield came to Austin and became renowned for his breast surgery expertise. He set up his own practice in 2017. Here, he offers the men and women of Austin a full range of cosmetic procedures, both surgical and non-surgical, addressing the full array of breast, body and face. Born and bred in Las Vegas, Austin plastic surgeon Dr. Whitfield received his medical degree from the University of Las Vegas School of Medicine. This was followed by six years of surgical training, as well as his plastic surgery residency at Indiana University Medical Center. He returned to Nevada for a one year microsurgery fellowship before settling down to practice and teach at the Medical College of Wisconsin for seven years. Board-certified by the American Board of Plastic Surgery, Dr. Whitfield's approach to medicine has really been shaped by both his upbringing and his education. As a child of the “wild west,” he was born with an adventurous spirit. One of the reasons that he was drawn to plastic surgery is the constant innovation. In the field of plastic surgery, with innovative techniques and technologies developed each year, there are simply issues for which a solution has yet to be invented. Dr. Whitfield tempers his intrepid attitude with Midwestern pragmatism. It makes for a pretty winning combination.

Over the years, stem cells have gained significant attention for their remarkable ability to transform into various cell types, presenting immense potential for regenerative medicine and treatment for a wide range of diseases. This growing interest has been driven by a series of groundbreaking discoveries and significant advancements in stem cell research. In the context of breast implants and breast implant illness, stem cells offer promising solutions for tissue regeneration and recovery, providing new hope for those seeking alternative treatments. Whether you're curious about the science behind stem cells or considering a procedure involving fat transfer, this episode is packed with valuable insights to guide you on your journey to better health and wellness. Let's explore more about how stem cells are transforming the medical field, providing new avenues for treatment and recovery. We'll dive into valuable insights and the latest advancements, helping you understand the incredible potential of stem cells and their benefits. Fat transfer surgery for breast augmentation and reconstruction I've recently attended several notable conferences where I gained valuable insights and innovations that I'm eager to integrate into our clinic. Some of these advancements include the incorporation of more lymphatic massage techniques, the introduction of NanoVi technology to improve protein folding and recovery, and the use of H-Wave therapy to further enhance lymphatic drainage and aid in patient recovery. For today, however, let's focus on fat transfers. Drawing from my extensive experience with fat transfers, a technique I've refined over many years, I explain that fat transfers are effective because they use the patient's own tissue, making them autologous and thus free from the risks associated with donor tissues, such as genetic mismatches. Fat transfers are versatile, as adipose-derived stem cells can differentiate into fat cells, bone cells, or cartilage, providing a range of benefits. My initial interest in this technique stemmed from a personal desire to regenerate cartilage in my knees after multiple surgeries, leading to a deep understanding of the procedure's potential. With extensive experience in sarcoma reconstruction, I can confidently say that fat transfers are safe when performed correctly. It's essential not to transfer fat to areas with existing tumors or sarcomas, as these mesenchymal regions could complicate the procedure. For breast augmentation and reconstruction, fat transfers have been effective for many years, and I have conducted numerous procedures since 2005. Successful outcomes depend on transferring a mixture of adipocytes, vascular cells, and adipose-derived stem cells. This technique requires precise placement of fat in specific areas to avoid complications and ensure proper integration with the surrounding tissue. There were early safety concerns regarding fat transfers for cosmetic purposes, such as buttock augmentation, due to technical issues when the procedure first gained popularity in South America and Miami. However, with advancements in techniques and improved safety measures, fat transfers for both buttock and breast augmentation have become reliable and effective procedures. Fat transfer for breast implant illness, including stem cells and healing When the skin gets really tense, you'll notice a condition called "peau d'orange," where the surface of the skin starts to look like the surface of an orange. This indicates too much pressure and that expansion should stop. Unlike implants, which can hold their shape and maintain more volume, fat cannot be continuously added. The amount of fat that can be added depends on the initial condition of the skin. For younger clients with tight skin, multiple sessions may be needed to gradually increase volume. In cases where I remove implants that have been in place for a long time, often after weight changes, pregnancies, or breastfeeding, the skin is usually stretched out. After removing the implant with its capsular material intact, I don't fill the old implant pocket and instead, place the fat beneath the skin, where it belongs, and let it heal. Adipose-derived stem cells in the fat offer numerous benefits, aiding in wound rejuvenation and healing. They can help turn genes on, produce exosomes, modulate immune responses, and improve mitochondrial function. This is why fat transfers are more than just about the fat itself – they bring substantial healing properties. To maintain the results over time, factors like diet, detoxification ability, and gut health are crucial. We strongly advocate for fat transfers, leveraging the healing power of stem cells. We also offer stem cell harvesting and banking, a process I personally undergo every three to six months. Using our cell surgical device and extensive experience since 1998, we continually strive to enhance our offerings and improve patient outcomes. We offer a variety of wellness products and supplies to help you on your recovery journey. So make sure to check out our online store at https://drrobssolutions.myshopify.com/ for extra resources and support. Browse our collection today to find everything you need for a healthier, more vibrant you! For any inquiries or concerns, feel free to connect with us on Instagram (@breastimplantillnessexpert). *About Dr. Rob's Solutions Podcast * Austin's natural plastic surgeon Dr. Robert Whitfield brings you the true stories of actual patients, navigates through their surgical and non-surgical treatment options, then reveals their chosen path forward and the results they achieved. Dr. Rob is a board certified plastic surgeon and Austin's Natural Choice for plastic surgery, laser and energy treatments, and aesthetics. Visit Dr. Rob's Austin plastic surgery (https://www.drrobertwhitfield.com/) practice website or follow him on Instagram at @drrobertwhitfield (https://www.instagram.com/drrobertwhitfield/) Dr. Rob's Solutions is a production of TeamPodcast.com (https://www.teampodcast.com/)

CardioNerds (Drs. Richard Ferraro, Gurleen Kaur, and Rupan Bose) discuss the growing epidemic of obesity and dive into the role of its procedural management with Dr. Steve Nissen, Chief Academic Officer at the Cleveland Clinic HVTI and past president of the American College of Cardiology. This is an exciting topic that reflects a major inflection point in cardiovascular care. In this episode, we discuss the importance of addressing obesity in cardiovascular care, as it is a major driver of cardiovascular disease and the progression of associated cardiovascular comorbidities. We look at the role of bariatric surgery and its ability to produce sustained weight loss. Finally, we look into the emerging role of new medical therapies such as GLP1 and GIP agonist medications. Notes were drafted by Dr. Rupan Bose and episode audio was edited by CardioNerds Intern Dr. Atefeh Ghorbanzadeh. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - Procedural Management of Obesity with Dr. Steve Nissen Obesity is associated with adverse cardiovascular outcomes. Returning to a healthy weight can largely prevent the downstream consequences of obesity. Regarding lifestyle modifications, diet alone is insufficient in sustaining prolonged weight loss. It is associated with short-term weight loss, but it is generally necessary to supplement with exercise and activity to ensure sustained weight loss. Bariatric surgery should be considered for patients with BMI ≥40 kg/m2 or BMI ≥35 kg/m2 with obesity-related comorbid conditions who are motivated to lose weight and who have not responded to behavioral treatment with or without pharmacotherapy. New emerging medications, including GLP1 receptor agonists, GIP receptor agonists, and glucagon receptor agonists, are beginning to approach weight loss levels that were previously only seen with bariatric surgery. Further research in this dynamic area is ongoing. Show notes - Procedural Management of Obesity with Dr. Steve Nissen Notes drafted by Dr. Rupan Bose. What is the role of obesity in the burden of cardiovascular disease, and why is it so important for CardioNerds to address it? According to the AHA, approximately 2.8 to 3.5 billion people worldwide are either overweight or obese. It is estimated that by 2030, 30% of people in the US will have a BMI greater than 30. Adipose tissue is associated with cytokine release. Cytokines, in turn, can activate and increase levels of IL-1 beta, IL-6, and CRP, leading to an increased inflammatory state. This pro-inflammatory state then accelerates the rate of cardiovascular disease. Obesity is also associated with significant joint and orthopedic diseases, which further impact patients' quality of life and morbidity. Additionally, obesity is associated with NASH cirrhosis. These adverse liver outcomes hold additional significant systemic implications and morbidity. How do you determine one's goal weight and goal BMI? Is BMI a good standard for measuring obesity? BMI is a variable of both weight and height. However, it cannot differentiate those whose weight is from adipose tissue versus from muscle mass. Therefore, BMI measurements can sometimes be misleading. Waist circumference may be a better measurement standard for obesity and risk assessment. The “apple shape” body type, with more abdominal fat, is associated with higher inflammation and cardiovascular risk than the “pear-shaped” body type, which is where there is more fat deposition in the buttocks a...

Show Notes: https://wetflyswing.com/591  Presented by: Visit Helena, MT Sponsors: https://wetflyswing.com/sponsors  In this episode, we chat with Justin Waayenberg from Adipose Boatworks to delve into the groundbreaking world of resin infusion in drift boats, offering anglers the ultimate guide to navigating the transformative trends in boat durability and weight. As we unravel the secrets behind choosing the perfect drift boat for your adventures on the Missouri River and beyond, listeners are treated to invaluable safety tips, ensuring an unmatched fly fishing experience. This episode promises to equip you with the knowledge and inspiration to take your fly fishing journey to new heights, all while emphasizing conservation and the deep-rooted passion that connects us to the rivers we cherish.   Episode Chapters with Justin Waayenberg on the Future of Drift Boats 3:05 - Justin discusses Adipose Boatworks' dedication to producing high-quality, top-tier boats, comparing their brand's quality to well-known companies. A significant focus of the discussion is on the adoption of resin infusion technology, a method that Adipose has been researching and perfecting for over three years. Additionally, he touches on the environmental considerations of their manufacturing process and how it compares to using materials like carbon fiber. 14:37 - He talks about their range of models and the design philosophy behind them. Adipose offers three main models: the Flow Skiff, the Runoff, and the South Fork Skiff. The Flow Skiff, their flagship model, is designed for the specific needs of western Rocky Mountain rivers, offering stability, low draft, and maneuverability in shallow waters and windy conditions. It's particularly suitable for fishing with three people, a common scenario among fly anglers. The Runoff model caters to those needing a boat that can handle bigger water and class three rapids, featuring a larger bow for more significant wave trains while maintaining maneuverability. Unlike traditional dory designs meant for navigating big rapids rather than fishing, Adipose's designs aim to provide a versatile solution for anglers. The third model, the South Fork Skiff, is a traditional design dating back to the late '80s, characterized by its flat bow (pram design) and low sides, making it ideal for two anglers. Despite not being a big seller, it has a cult following among those who appreciate its design for specific fishing conditions. 21:57 - Justin highlights the thoughtful design considerations that go into each model, such as optimizing space for gear storage, ensuring stability, and enhancing maneuverability. These skiffs are not only capable of handling multi-day trips on rivers like the Smith River in Montana but also excel in efficiently utilizing space to accommodate gear and providing a stable fishing platform. 29:24 - We talk about his home waters. His go-to river is the expansive Missouri River, stretching from Tosin and Three Forks to Fort Peck and the North Dakota border. This river offers a diverse fishing experience, from fly fishing for trout to casting for pike and carp. He also highlights Helena, Montana, as an ideal spot for anglers due to its central location. From Helena, numerous renowned rivers like the Blackfoot, Big Hole, Yellowstone, Madison, and others are within a two-hour drive, offering a variety of fishing experiences based on weather conditions and target species. 32:49 - For those seeking guidance or local insights on the Missouri River, Justin recommends several fly shops, notably Headhunters in Craig and Trout Montana in Cascade, known for their expertise and willingness to share information with anglers. Other notable mentions include Montana Fly Goods in Helena and Wolf Creek Angler. These shops are praised for their knowledgeable staff, extensive fly selection, and up-to-date river reports, making them invaluable resources for anyone fishing the Missouri River. 34:34 - Justin tells the optimal times and strategies for fishing the Missouri River. Early spring, particularly mid-April to late April, is recommended for experiencing significant dry fly hatches, with the river temperature climbing into the high forties and low fifties. For those willing to brave the colder temperatures, Justin notes that fishing conditions on February 19th, for instance, could allow an angler to catch a hundred fish in a day. The conversation also covers the importance of following weather patterns and choosing fishing techniques based on seasonal changes. Justin mentions that as the season progresses, anglers can expect a variety of hatches, including PMDs, Tricos, and Caddis, but advises caution in late summer and fall when weed growth can complicate fishing. 40:35 - The conversation touches on the geographical and ecological transitions around Helena, the Continental Divide, and the historical significance of areas like the Gates of the Mountain, described by Lewis and Clark. Justin highlights the rich fishing experiences available across different water types in Montana, from tailwaters to freestones and reservoirs, underscoring the state's commitment to natural river management and the absence of river stocking since the mid-20th century. 45:19 - We talk about an upcoming drift boat clinic organized by Adipose Boatworks, scheduled for April 27th. This clinic, offered in collaboration with Mending Waters Montana—a Helena-based veterans organization—aims to educate participants on all aspects of drift boat handling. Mending Waters Montana is dedicated to supporting veterans through fishing trips, rod building, fly tying, and offering access to exclusive private waters and popular fishing destinations like the Missouri River. The clinic covers a comprehensive range of topics from the basics of drift boat design differences, preparation and launching techniques, to rowing strategies and fishing from a drift boat. The event is free, with attendees encouraged to donate to Mending Waters Montana. Those interested in participating in the clinic can contact Adipose Boatworks via email to register. 48:41 - We dig into safety tips for drift boat handling, which are crucial for anyone attending their drift boat clinic or navigating rivers independently. Key safety advice includes: 1. Always Pull, Never Push: Justin emphasizes the importance of pulling rather than pushing to slow down and maintain control of the drift boat. This technique gives the rower more time to react to obstacles by slowing the boat's speed, allowing for better maneuverability. 2. Avoid Tying Knots in the Anchor Rope: A common mistake is tying knots in the anchor rope to prevent losing the anchor. However, Justin advises against this because, in situations where the boat starts behaving unpredictably, it's safer to let the anchor rope go to avoid the boat capsizing. The cost of replacing an anchor is minimal compared to the potential loss of the boat or, more importantly, a life. 3. Don't Drop Anchor in Fast Water: Dropping an anchor in fast-moving water can lead to dangerous situations, including the boat getting lodged and potentially sinking. Justin recounts a tragic incident on the Missouri River where a boat capsized and resulted in a fatality due to the anchor being dropped in fast water. He advises rowers to anchor in calmer water or eddies where the bottom can be seen and the risk of getting the anchor stuck is minimized. 4. Floor Release Anchor Systems: Most drift boats come with a floor release anchor system. In case of emergency, rather than reaching for a knife or attempting to untie knots, the best action is to simply release the anchor by stepping on the floor mechanism, allowing the boat to free itself from the anchor's hold. 53:26 - Justin provides a variety of restaurant options in Helena ranging from casual to slightly more upscale, catering to different tastes and budgets. For a local beverage after fishing, Justin suggests visiting one of Helena's breweries, highlighting Lewis and Clark Brewery as a nationally recognized establishment. 56:27 - Justin emphasizes the appeal of Helena, Montana as a family-friendly town with plenty of outdoor activities, devoid of the college town atmosphere. He also highlights local attractions like the state capital building and Blackfoot Brewery, and emphasizes Helena's growing scene that caters well to families and outdoor enthusiasts alike. Show Notes: https://wetflyswing.com/591 

BUFFALO, NY- April 9, 2024 – A new #researchpaper was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, “CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction.” Modulated by differences in genetic and environmental factors, laboratory mice often show progressive weight gain, eventually leading to obesity and metabolic dyshomeostasis. The geroneuroprotector CMS121 has a positive effect on energy metabolism in a mouse model of type 2 diabetes. In this new study, researchers Alcir L. Dafre, Saadia Zahid, Jessica Jorge Probst, Antonio Currais, Jingting Yu, David Schubert, and Pamela Maher from Salk Institute for Biological Studies, National University of Sciences and Technology (NUST) and Federal University of Santa Catarina investigated the potential of CMS121 to counteract the metabolic changes observed during the ageing process of wild type mice. “This comprehensive analysis aimed to further understand how CMS121 influences the metabolic landscape, paving the way for potential therapeutic applications beyond its established geroneuroprotective benefits.” Control or CMS121-containing diets were supplied ad libitum for 6 months, and mice were sacrificed at the age of 7 months. Blood, adipose tissue, and liver were analyzed for glucose, lipids, and protein markers of energy metabolism. The CMS121 diet induced a 40% decrease in body weight gain and improved both glucose and lipid indexes. Lower levels of hepatic caspase 1, caspase 3, and NOX4 were observed with CMS121 indicating a lower liver inflammatory status. Adipose tissue from CMS121-treated mice showed increased levels of the transcription factors Nrf1 and TFAM, as well as markers of mitochondrial electron transport complexes, levels of GLUT4 and a higher resting metabolic rate. Metabolomic analysis revealed elevated plasma concentrations of short chain acylcarnitines and butyrate metabolites in mice treated with CMS121. “The diminished de novo lipogenesis, which is associated with increased acetyl-CoA, acylcarnitine, and butyrate metabolite levels, could contribute to safeguarding not only the peripheral system but also the aging brain. By mimicking the effects of ketogenic diets, CMS121 holds promise for metabolic diseases such as obesity and diabetes, since these diets are hard to follow over the long term.” DOI - https://doi.org/10.18632/aging.205673 Corresponding authors - Pamela Maher - pmaher@salk.edu and Alcir L. Dafre - alcir.dafre@ufsc.br Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.205673 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts About Aging-US Aging publishes research papers in all fields of aging research including but not limited, aging from yeast to mammals, cellular senescence, age-related diseases such as cancer and Alzheimer's diseases and their prevention and treatment, anti-aging strategies and drug development and especially the role of signal transduction pathways such as mTOR in aging and potential approaches to modulate these signaling pathways to extend lifespan. The journal aims to promote treatment of age-related diseases by slowing down aging, validation of anti-aging drugs by treating age-related diseases, prevention of cancer by inhibiting aging. Cancer and COVID-19 are age-related diseases. Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Diets high in seed oils are linked with migraines, chronic pain and developmental delay in children. Here's the truth about seed oils and their impact on your health.  Support your Intermittent Fasting lifestyle with the Berberine Fasting Accelerator  by MYOXCIENCE: https://bit.ly/berberine-fasting-accelerator Use code Podcast to save at checkout Link to research and show notes: https://bit.ly/3SYC94i Time Stamps:  00:00 Linoleic acid oxidizes easily. 00:50 Linoleic acid is stored in your fat tissue with a half life of over 680 days. 01:40 25% of total fatty acids in your fat cells comes from linoleic acid. 02:30 Soy, cotton seed, canola, and sunflower oil are in most processed foods. 03:05 Pain can be influenced by chronic seed oil consumption. 05:30 Adipose tissue linoleic acid has doubled. 06:00 We are eating less beef, pork, butter, and lard, and more chicken and seed oils. 07:25 Adipocytes become inflamed. 08:10 Inflammation from fat worsens metabolic health. 09:20 Oxidation of lipids in LDL is a major risk factor for coronary heart disease. 10:20 High intake of omega 6 fats from seed oils is associated with depression and poor mental health. 12:00 Omega 6 fat is liked to persistent pain, headaches, irritable bowel, low back pain, and rheumatoid arthritis. 12:45 Omega 3 fats are linked with reduced pain.  

This is a MUST LISTEN episode of The Sonography Lounge, hosted by Lori Green and Trisha Reo where we dive into a high-level discussion on various regenerative medicine options, and unveil the pivotal role ultrasound plays in musculoskeletal (MSK) injury diagnosis and treatment. This episode is for both healthcare providers and patients interested in Regenerative medicine treatment options. We discuss Prolotherapy, Platelet Rich Plasma (PRP), Adipose Derived Stem Cells, and Bone Marrow concentrate. This episode focuses mostly on Prolotherapy and PRP. Due to Time constraints, we will be doing follow up episodes on Adipose Derived Stem Cells (aka Lipoaspirate), and Bone Marrow Aspirate.   Joining us today are distinguished experts: Dr. John Broussard, (https://www.thealliancerx.com/) is board certified in Family Medicine and Sports Medicine and specializes in both regenerative and osteopathic manipulative medicine. He earned his Doctor of Osteopathic Medicine degree from Nova Southeastern University in South Florida and completed his residency training in Family Medicine at an osteopathic hospital, practicing in the urgent care setting. He then followed to complete a Sports Medicine Fellowship at the Institute for Non-Surgical Orthopedics in Florida. In 2014, he integrated ultrasound into his practice for diagnostics and guided interventional procedures. In 2020, he and his brother opened their own practice right here in sunny St. Pete. Together, they help active adults and athletes quickly overcome injury and get back to the activities they love. Dr. David Wang, (https://www.rosm.org/) Who earned his Doctor of Osteopathic Medicine degree from The West Virginia School of Osteopathic Medicine, where he was selected as a teaching Fellow in Osteopathic Manipulative Medicine. He completed his residency training in Physical Medicine and Rehabilitation at Harvard Medical School/Spaulding Rehabilitation Hospital, during which time he was appointed Chief Resident.  He is a founding partner and Director of Education and Training of Regenerative Orthopedics and Sports Medicine, with offices throughout the Metropolitan DC area.  He specializes in diagnostic musculoskeletal ultrasound, non-fluoroscopic interventional spine, osteopathic manual treatment, and regenerative medicine including prolotherapy, PRP, orthobiologics, and lipoaspirate stem cell therapies.    Dr. Imran Siddiqui, (https://www.rosm.org/) Currently serves as a Partner and the Director of Clinical Operations at Regenerative Orthopedics and Sports Medicine in Washington, DC.  He graduated medical school Cum Laude from Thomas Jefferson University where he was inducted in to the Alpha Omega Alpha honor society.  After which, he completed his residency at Harvard Medical School and Spaulding Rehabilitation Hospital where he trained extensively in musculoskeletal ultrasound and regenerative medicine and was awarded resident teacher of the year. Currently, Dr. Siddiqui also servers as an ultrasound and instructor and board member for the Interventional Orthobiologic Foundation.  He also has instructed at Harvard Medical School, Orthosound Educational Institute, and the American Academy of PM&R.   MSK ULTRASOUND RESOURCES   CME and Cross training resources: Gulfcoast Ultrasound Institute (Training materials and programs):https://www.gcus.com/   Certification Agencies: American Board of Emergency Medicine (ABEM): https://www.abem.org/public Sonographer / Physician: American Registry of Diagnostic Medical Sonography (ARDMS):http://www.ardms.org/ Physicians: Alliance for Physician Certification & Advancement (APCA):http://www.apca.org/ Point of Care Healthcare Providers: Point of Care Certification Academy (POCUS):http://www.pocus.org/ Sonographer / Physician: Cardiovascular Credentialing International (CCI):http://www.cci-online.org/  Find an accredited long term Ultrasound Program: https://www.caahep.org/Students/Find-a-Program.aspx

According to the National Institutes of Health, more than two in five adults have obesity in the United States, and nearly one in three is overweight. To equip health care practitioners with the resources they need to treat patients with obesity, the Endocrine Society recently held its innaugual obesity fellows program, an exclusive, application-based, educational activity for current fellows. The program covered a wealth of information, and host Aaron Lohr talks with Amy Rothberg, MD, DABOM, program chair and a clinical professor of internal medicine at the University of Michigan’s School of Public Health. If you weren’t able to attend the fellows program, we have a free series of on-demand lectures available online, and those are accredited. With thanks to Lilly USA LLC and Novo Nordisk for making both the obesity fellows program and this podcast episode possible through an unrestricted, educational grant. Show notes, including a link to the Endocrine Society Learning Center for earning ABIM points and AMA PRA Category 1 credits, are available at https://www.endocrine.org/podcast/enp81-obesity-fellows-program — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

According to the National Institutes of Health, more than two in five adults have obesity in the United States, and nearly one in three is overweight. To equip health care practitioners with the resources they need to treat patients with obesity, the Endocrine Society recently held its innaugual obesity fellows program, an exclusive, application-based, educational activity for current fellows. The program covered a wealth of information, and host Aaron Lohr talks with Amy Rothberg, MD, DABOM, program chair and a clinical professor of internal medicine at the University of Michigan’s School of Public Health. If you weren’t able to attend the fellows program, we have a free series of on-demand lectures available online, and those are accredited. With thanks to Lilly USA LLC and Novo Nordisk for making both the obesity fellows program and this podcast episode possible through an unrestricted, educational grant. Show notes, including a link to the Endocrine Society Learning Center for earning ABIM points and AMA PRA Category 1 credits, are available at https://www.endocrine.org/podcast/enp81-obesity-fellows-program — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

According to the National Institutes of Health, more than two in five adults have obesity in the United States, and nearly one in three is overweight. To equip health care practitioners with the resources they need to treat patients with obesity, the Endocrine Society recently held its innaugual obesity fellows program, an exclusive, application-based, educational activity for current fellows. The program covered a wealth of information, and host Aaron Lohr talks with Amy Rothberg, MD, DABOM, program chair and a clinical professor of internal medicine at the University of Michigan’s School of Public Health. If you weren’t able to attend the fellows program, we have a free series of on-demand lectures available online, and those are accredited. With thanks to Lilly USA LLC and Novo Nordisk for making both the obesity fellows program and this podcast episode possible through an unrestricted, educational grant. Show notes, including a link to the Endocrine Society Learning Center for earning ABIM points and AMA PRA Category 1 credits, are available at https://www.endocrine.org/podcast/enp81-obesity-fellows-program — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast

Preeti Sudheendra, MD, is a breast cancer medical oncologist at Ohio State/The James Cancer Hospital and has been in practice for almost 15 years. She also has an expertise in seeing patients who may be at high risk for developing breast cancer in the future due to genetic or other predispositions. Dr. Sudheendra has been involved with the American College of Lifestyle Medicine since 2022 and is the incoming co-chair for the ACLM Breast Cancer Subcommittee. Links:Connect with Dr. Sudheendra on Twitter/X and LinkedIn

Does a higher BMI sometimes lead to better outcomes? Is BMI  what we should be using to measure obesity? Whether you are considered obese, overweight, normal weight, or underweight... your BMI can be misleading. Tina & Leah delve into the details and give you some advice to achieve the ultimate goal: living your best life as long as you possibly can!Join us for free to get the links we refer to in this episode!Our September Sponsor:Pinkn' Patch's mission is to lift the burdens of fighting cancer so patients and their families can focus on healing. Through your contributions and partnerships with local businesses, this worthy initiative can expand into a powerful organization that helps thousands of patients and their families nationwide.For more information, go to pinkn.org.Support the showWe hope you find our talks useful and entertaining! Please rate & review us! This helps us get found by listeners like you!Share this podcast with someone you love! https://www.thecancerpod.com Email us: thecancerpod@gmail.comWe are @TheCancerPod on: Instagram Twitter Facebook We appreciate your support! THANK YOU!

References Telemann Georg P. 1765. Overture D Major, TWV 55:D18 | Tafelmusik https://youtu.be/8r-IFLtN9x4?si=T2hp65oGT--dTivY Leukemia 2020 volume 34, pages 75–86 Nat Cell Biol. 2019 Mar; 21(3): 397–407 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Haydn, Michael. 1760. Salve Regina in G MH32. https://youtu.be/u_Xjo5KJ3mg?si=kmKaaBJMvUgs_blX Leukemia 2020. volume 34, pages 75–86 CELL 2006. Volume 126, Issue 3, Pages 503-514 Nat Cell Biol. 2019 Mar; 21(3): 397–407. Curr Opin Pharmacol. 2021 Apr; 57: 107–116. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Saint-Saens. C. 1886. Symphony 3 (avec orgue) OP.78 J Clin Invest. 2011 Dec 1; 121(12):4903–4915 Cell Metab. 2022 Dec 6; 34(12): 2036–2046.e8. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Thyroid Talk with Dr. Angela Mazza, DORecorded Wednesday, Sept. 20, 2023SHOW NOTES EPISODE 22Part Two: Trouble With Your Weight?Host: Dr. Angela Mazza, DOCo-host: Dawn Sheffield I'm Dr. Angela Mazza, D.O., a thyroid, endocrine, and metabolism specialist with a private practice in Central Florida.  My goal for this podcast is to define and demystify the thyroid gland, and thyroid-related medical conditions.  By providing information in an easy-to-understand format, we hope to help patients better understand the ways in which their bodies work, and to help them thrive.  My goal is to help us live more fulfilling lives by taking control of our health, to feel our best. I wanted to do this podcast to provide life-saving education and encourage patients to see a doctor in time to prevent or minimize damage.  That's deeply fulfilling.  I enjoy helping folks understand how all aspects of their lives are tied to both thyroid and overall health.  In fact, this is why I went into endocrinology.  It's a medical art that combines science with the study of our lives—and all that they encompass.   To recap just some of what we covered in this episode, not necessarily in this order:·        Metabolism;·        Cortisol's role;·        Adipose tissue: it's alive;·        Weight goals: HEALTH;·        Weight regulation hormones;·        BMI--Body Mass Index--explained;·        Exercise vs. nutrition for weight loss;·        Best of all, we learned that we CAN impact our thyroid health!  Please watch for pre-order availability for Dr. Mazza's book, Thyroid Talk: An Integrative Endocrinologist's Guide to Optimal Thyroid Health.  As an added bonus, there will be an online master course, related to the book, to help guide you to optimal thyroid health.   For information on advance copies, being part of the book launch team, and the chance to write a review early-on, forward your name and email to thyroidtalk.mazza@gmail.com or our website at metaboliccenterforwellness.com   And for information on supplements mentioned in various episodes of this podcast, please visit the Wellness Store at metaboliccenterforwellness.com   Please send comments, show ideas, and questions for future episodes to thyroidtalk.mazza@gmail.com  We may disclose your general location on air (the city or town for example), but will NOT read your name NOR your address on the show.  We reserve the right to edit your input as necessary.  Please stay in touch!  Check out our YouTube channel; the website at metaboliccenterforwellness.com, as well as Facebook, Instagram, and TikTok.  In our next show, episode 23, we'll have a special guest: Jennifer Holkem, a thyroid patient and enthusiastic advocate for non-surgical thyroid treatment options, like RFA--Radio Frequency Ablation.  One of Jennifer's goals is to educate other thyroid patients and providers on her own experience, and what she's learned about maintaining thyroid health. Citations, references, and additional information you may find helpful:Mazza A.  Thyroid Talk: An Integrative Endocrinologist's Guide to Optimal Thyroid Health.   Don't forget to ask your healthcare provider about any specific questions regarding your wellness.  This podcast is meant for educational purposes only. CopyrigCheck out our YouTube channel - Dr. Angela Mazza, our website at Metabolic Center for Wellness, our FaceBook and our Instagram page.

References Cream 1968 Wheels of Fire J Neuroinflammation. 2019; 16: 34. Front Immunol. 2019; 10: 345. Cell Metabolism 2023. Volume 35 Issue 4. 601-619.e10 Sci Signal. 2017 Jan 31; 10(464):eaaf7478 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Many of us think of adipose tissue as just a place to store excess fat to be used for energy. However, adipose tissue is very biologically active and secretes some important hormones and mediators called adipokines. These messengers help regulate glucose and lipid metabolism, control hunger, and affect insulin levels. That being said, ALL of our hormones work together like a symphony – cortisol, thyroid hormones, sex hormones, and don't forget the adipokines. In today's episode, we discuss important bioactive messengers created by our fat tissue (leptin and adiponectin), how they affect us systemically, and strategies to optimize them. Today on The Lab Report: 3:40 Adipose tissue, adipokines, and types of fat 7:40 What are adipokines? 10:25 Adiponectin does great things 13:00 How to increase adiponectin 14:20 Better Know a Biomarker – Leptin! 17:40 Obesity and leptin resistance 19:25 Treating leptin resistance 21:35 Leptin vs. ghrelin 23:15 Adiponectin/leptin ratio Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week's episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don't forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

References Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55 Int J Biol Sci. 2015; 11(11):1272–1280 Front. Physiol., 01 June 2018 Int. J. Mol. Sci. 2019, 20(6), 1505 Front Immunol. 2023; 14: 1149366 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Inn Med (Heidelb). 2023 Apr;64(4):313-322. JBC 2001. Volume 276, Issue 31, August. Pages 28799-28805. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Schubert, Franz. 1824. March.String Quartet #14 in D minor, D.810 Hypertension. 2002;39:1088–1094 Physiol Rev. 2018 Apr1;98(2):641-665. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Dr Glenn McConell chats with Professor David Wright from the University of British Columbia, Canada. He has undertaken a lot of important work on the effect of exercise on muscle glucose uptake and mitochondria and then has branched out to examine the effect of exercise training on mitochondria in adipose tissue (fat). We discussed his work around that and then talked about an interesting new focus of his work around the metabolic effects of antipsychotics. He is finding that exercise can prevent the acute blood glucose raising effects of antipsychotics. A very interesting chat.0:00. Introduction and how David got into research6:10. His transition from muscle to fat research10:05. Exercise activates AMPK in muscle and fat10:57. Adipose tissue breakdown during exercise13:58. Adrenaline/epinephrine15:28. Exercise training effects on fat mitochondria21:00. Why so much fat turnover during exercise24:00. Fat use during ex in lean vs obese26:25. Adrenaline regulation of fat adaptations to ex training29:50. AMPK regulation of fat32:05. Cross talk between organs during exercise34:55. White, beige, brown adipose tissue39:00. Human vs rodents brown adipose tissue44:25. Adipokines and exercise training48:40. Ectopic fat49:40. Antipsychotics, obesity and diabetes51:15. Each dose of an antipsychotic increases blood glucose53:00. Exercise prevents these glucose effects of antipsychotics59:00. GLP-1, glucagon and antipsychotics1:03:20. Poor exercise adherence, do fasting instead?1:05:15. Ketogenic diets and antipsychotics1:08:50. Ketogenic diets and mental health1:11:03. Clinicians awareness etc.1:12:45. Sex and age differences1:15:00. Acute vs chronic effects1:15:40. Takeaway messages1:19:27. Outro (9 seconds)Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise's effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).Connect with Inside Exercise and Glenn McConell at:Twitter: @Inside_exercise and @GlennMcConell1Instagram: insideexerciseFacebook: Glenn McConellLinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460ResearchGate: Glenn McConellEmail: glenn.mcconell@gmail.comSubscribe to Inside exercise:Spotify: shorturl.at/tyGHLApple Podcasts: shorturl.at/oFQRUYouTube: https://www.youtube.com/@insideexerciseAnchor: https://anchor.fm/insideexerciseGoogle Podcasts: shorturl.at/bfhHIAnchor: https://anchor.fm/insideexercisePodcast Addict: https://podcastaddict.com/podcast/4025218Not medical advice

References Cells. 2019 Mar; 8(3): 227 Chest. 2016 Jul; 150(1): 91–101 JCI Insight. 2016 Nov 17; 1(19): e87748. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

References Inn Med (Heidelb). 2023 Apr;64(4):313-322 JBC 2001.Volume 276, Issue 31, Pages 28799-28805 Frein, Daniel. 2006. “Signaling and Redox Regulation by Nitric Oxide, Superoxide and Carbon Monoxide.” Hypertension. 2002;39:1088–1094 Nat Metab. 2022 Sep;4(9):1202-1213 JCI Insight. 2016 Nov 17; 1(19): e87748 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

References Graduate Biochemistry lectures-Guerra Front Immunol. 2021; 12: 746151 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

Heartburn, the burning sensation in your chest caused by acid reflux, affects millions worldwide. While over-the-counter medications and prescription drugs may offer relief, many people look for natural home remedies, which leads them to wonder, “Do essential oils help with heartburn?” In this article, I'll review what causes heartburn, how essential oils may help alleviate some symptoms, and how to prevent it. Prevalence In the United States alone, it is estimated that approximately 60 million adults experience heartburn at least once a month, with 15 million suffering daily.El-Serag, H. B., Sweet, S., Winchester, C. C., & Dent, J. (2014). Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut, 63(6), 871-880. Men are more likely to experience heartburn and gastroesophageal reflux disease (GERD) than women, likely because of men's hormones, lifestyles, diets, and alcohol consumption.Nilsson, M., Johnsen, R., Ye, W., Hveem, K., & Lagergren, J. (2003). Obesity and estrogen as risk factors for gastroesophageal reflux symptoms. JAMA, 290(1), 66-72. The prevalence of heartburn and GERD increases with age. One study found that GERD symptoms increased from 10.8% in individuals aged 18-24 to 21.8% in those aged 65-74.Locke, G. R., Talley, N. J., Fett, S. L., Zinsmeister, A. R., & Melton, L. J. (1997). Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology, 112(5), 1448-1456. This increase may be attributed to age-related changes in esophageal function and increased gastric acid secretion. Causes Heartburn occurs when stomach acid flows back into the esophagus, causing irritation and a burning sensation in the chest area. This condition, also known as acid reflux, can be triggered by obesity, smoking, certain medications, and consuming acidic, fatty, or spicy foods.Mayo Clinic. (2018). Heartburn. Retrieved from https://www.mayoclinic.org/diseases-conditions/heartburn/symptoms-causes/syc-20373223 Lifestyle habits like stress and lack of sleep can also contribute to heartburn episodes. I want to highlight obesity and medications, as they're often overlooked or ignored as causal factors. Obesity Obesity is a significant risk factor for the development of heartburn and gastroesophageal reflux disease (GERD). Obesity leads to heartburn and GERD through: Increased intra-abdominal pressure: Obesity, particularly central or abdominal obesity, increases intra-abdominal pressure. This increased pressure puts pressure on the stomach, which can cause the lower esophageal sphincter (LES) to weaken or open, allowing stomach acid to flow back into the esophagus, resulting in heartburn.Pandolfino, J. E., El-Serag, H. B., Zhang, Q., Shah, N., Ghosh, S. K., & Kahrilas, P. J. (2006). Obesity: a challenge to esophagogastric junction integrity. Gastroenterology, 130(3), 639-649. Hormonal changes: Adipose tissue in obese individuals can cause hormonal changes, including the release of adipokines and cytokines, which have been linked to inflammation and impaired LES function.Hampel, H., Abraham, N. S., & El-Serag, H. B. (2005). Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Annals of Internal Medicine, 143(3), 199-211. Esophageal motility disorders: Obesity may also be associated with esophageal motility disorders, which can contribute to developing heartburn and GERD.El-Serag, H. B. (2008). Role of obesity in GORD-related disorders. Gut, 57(3), 281-284. Medications Several medications can contribute to heartburn by weakening the LES, irritating the esophageal lining, or slowing gastric emptying. Some common medications associated with heartburn include: Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs, such as aspirin, ibuprofen, and naproxen, can irritate the esophageal lining and increase the risk of heartburn.Wolfe, M. M., Lichtenstein, D.

Show Notes:  https://wetflyswing.com/419 Presented by:  Mavrk, Zag, Country, Drifthook Sponsors:  https://wetflyswing.com/sponsors Have you ever had to uproot your entire life and go halfway across the globe to chase a dream? That's precisely what John Bond, the owner of Rena Fish Camp, did!  We are digging into Norway Fly Fishing today on the Swing! John Bond is here with us today to take us fishing in Norway and to talk about how he moved his drift boat, gear, and life from Montana to Norway amid COVID. We also find out how streamer fishing changed the game for him. Learn tips and tricks from the Umpqua signature Dragon tier himself as John takes us through the art of swinging for brown trout in Norway. Norway Fly Fishing Show Notes with John Bond 3:47 -  John's interest in fly fishing began early, having spent countless weekends traveling to fishing sites throughout the East Coast with his family. 05:20 - John worked as a butcher and part-time fly fishing guide in Vermont, but his ultimate goal was to move to Montana, a place his parents often talked about. 06:42 - He sold an old rod on Craigslist and made friends with the buyer's two sons, who offered him an apartment in Bozeman.  09:45 - In 2010, during his first streamer fishing trip in Missouri, John was amazed by how fish reacted to his Sculpzilla fly. This experience changed the fly fishing game for him. 11:25 - Just three months after moving to Montana, he invested $5,000 in a boat worth more than his Jeep Cherokee. 14:33 -  In 2013, he caught a 28-inch female brown trout on the Yellowstone River, and the experience changed his fishing game. 15:17 - John is an Umpqua signature tier for the Dragon, previously known as the Beefcake. 17:24 - We delve into John's fly fishing techniques and how he applies them to streamer and nymph fishing. He uses a Scientific Angler Sink Tip fly line.  22:00 - John breaks down the differences between the brown trouts in Montana versus the browns in Norway.   23:41 - A spin fisherman caught a 20-pound brown trout six years ago. John and his friend Christopher got a 25-inch brown on his third day in Norway. 25:05 - John talked about the Yellowstone Angler and James Anderson and how he opened the door to his guiding life back in Montana.  26:05 - John went to Norway with his wife in 2017. They visited Rena Fiskecamp in Norway, where the owners mentioned the camp might be up for sale. John jokingly suggested he would buy it and move to Norway, despite having no plans to leave Montana then. 27:32 - In 2019, John and his wife made the decision to move to Norway after she became pregnant with their second child. 30:37 - John and his friends went salmon fishing on the Orkla River in Norway, which is well-known for its fantastic Atlantic salmon fishing. After that, he went to Matt Haye's Winsnes Fly Fishing Lodge, where he had a brush with death. 35:39 - John tells us more about the Rena Fish Camp. The Rena River is one of the only rivers open to the public by buying a fishing license. 40:08 - We hear the story of how John moved his family, his gears, his brand new Adipose drift boat, and even his dog from Montana to Norway in the middle of the COVID-19 pandemic.  46:44 - John has been an ambassador with G. Loomis for several years through Yellowstone Angler. He is also an advisor with the Scientific Angler. 48:15 - We get a picture of life in Norway and the differences from life in the U.S. 58:24 - John talks more about his family's lodge and his guiding business on the Rena River. In summer, they have the midnight sun, and people can fish all night during those days.     1:03:00 - Norwegians traditionally have a culture of catching and keeping fish. The practice of catch and release has been steadily gaining popularity over the last 10 to 15 years. 1:04:43 - We hear the best time to visit their fish camp. People come from all over the world to catch Arctic Norwegian grayling.  1:13:45 - John tells the story of how he nearly died while salmon fishing using his brand new G. Loomis Asquith on the Gaula River. 1:17:25 - John ties a variety of flies. Wade Fellen had some luck fishing with the Dragon.  1:17:25 - John ties a variety of flies. Wade Fellen of the Big Hole Lodge had some luck fishing with the Dragon. We also did another episode about Norway with Erlend Nilssen. Show Notes:  https://wetflyswing.com/419    

In many watersheds, most wild steelhead returning each season will be caught and handled by anglers, some more than once. Regardless of our best intentions, some fish will die, and many will endure sublethal short and/or long-term impacts, such as reduced spawning success.Dr. Andy Danylchuk and his teams have researched the impacts of catch-and-release fishing on various recreational fisheries around the globe.In this episode of The Adipose, Andy shares the results of his study to evaluate the factors that influence C&R outcomes in wild steelhead on the Bulkley River in British Columbia and how improvements in catch-and-release survival can influence a population's ability to sustain or even grow, their numbers.  

Researchers are discovering how exercise causes muscles to make fat burning hormones and molecules called exerkines. In this show we dive into the details about the health benefits linked with exercise and exerkines. Support Healthy Hydration and Exercise Performance with the new Electrolyte Stix by MYOXCIENCE Nutrition: bit.ly/electrolyte-stix Save with code podcast at checkout  Link to references and show notes: https://bit.ly/3QoKbQT Time Stamps 0:00 Skeletal muscle is an endocrine organ. 0:10 Movement stimulates your skeletal muscle organ to release endocrine-like hormones and myokines (aka exerkines) that have systemic effects upon the brain, heart, liver, bone, mood, and more. 1:10 Movement/exercise can have anti-cancer properties. 1:50 Increases in exerkines influence microRNA increases. 2:40 Skeletal muscle is the largest organ of your body by weight. 4:55 Volume and intensity of exercise determines the duration and quantity of release of exerkines. 5:15 Start: Do 3 to 5 exercises for 3 to 5 reps, 3 to 5 sets, 3 to 5 days per week. Do the things you like. 6:00 Exerkines have paracrine and autocrine effects that effect muscle, the entire endocrine system, fat cells, immune system, bone, and brain. 7:30 Habitual exercise can induce sustained elevated increase in exerkines and the associations with disease reduction. 10:15 After exercise, there is a transient increase in proinflammatory interleukins, and a post exercise increase from skeletal muscle with systemic anti-inflammatory properties. 12:10 The anti-cancer effects of exercise go beyond the reduction in bodyfat. 13:30 Exerkine milieu lasts for several hours after exercise cessation.   14:05 Exercise can prevent or delay the onset of neural degenerative conditions. 15:30 Adipose tissue can release exerkines. 16:10 Your liver is a major source of many acute and chronic exercise-responsive cytokines. 17:10 Exercise affects your gut microbiome.  

Here is the link to participate: We are revisiting a SOLAR Room that was very successful in helping people lose weight, and many people experienced shifts in their habits. Not a week goes by that someone is requesting to continue this losing weight journey again... A Solar Room is opening... My wife lost about 12 pounds the month we did this SOLAR Room, and we had over 16 testimonials from this 7-days consecutive Energy Healing using multiple modalities and sending SEFI Frequencies. Many activations will be taking place: We will be healing certain glands in the body and ensuring that all hormones are being regulated to assist the body in losing weight. We will be working on any energies that cause you to sabotage yourself by missing out on exercise, not eating correctly, or curbing indulgences that don't serve your body in the short or long term. We will examine genetic programming, Adipose imbalances, Excess Stress Hormones, Gallbladder and Digestive malfunctioning, Toxins and Pathogens, Brain Lobes when malfunctioning cause weight gain,...and much more... Included: Guided meditation, SEFI Frequencies sent to the group, Conscious Integration Video, Inspired Message, and continuous assistance from my wife and I. We look forward to serving you! See you on the inside! --- Support this podcast: https://anchor.fm/healingthehealer/support

In this episode I sit down with Justin Waayenberg.  Justin grew up in Caledonia, Michigan on a small farm and struggled to make it through high school.  Justin joined the Army when he was just 17 years old as a Cavalry Scout.  In 2008 he was deployed to Iraq.  After returning from his deployment Justin moved to Montana in 2010 and left the Army in 2011.  Justin took a job with Adipose Boatworks, which at the time was a new drift boat company that had been created based out of Helena, MT.  When Justin started working at Adipose Drift Boats he ended up helping finish up their first boat.  He was quickly promoted to the production manager in the fall of 2010 and held that position until 2015 when he was promoted again to the General Manager of the company and has held the position with the company ever since and is now a part owner of the company. Additionally, Justin is the president of Mending Waters, MT a non-profit based out of Helena MT dedicated to healing veterans through fishing and nature.   I first met Justin in 2012 through the owner of the company Mike Ward (a close friend to both of us) and have worked with him in one capacity or another ever since then, as an Ambassador for the brand and most recently as a consultant for the company.  Justin's story is an inspiring example of change, commitment, and perseverance at the deepest level, one I look forward to exploring further today.  I am honored to call Justin a close friend, he has been an inspiration to me, and I personally think about his story often. Justin currently lives in Helena, MT with his girlfriend Kelly and his daughter Kenna.  Without further adieu please welcome Justin to the show.Be sure to subscribe to this show on iTunes, Spotify, and your favorite podcast hosting platform. Check our website (www.permittothink.com), subscribe to the newsletter, and get updates on the show.  Please forward the show onto anyone who you think might dig it. Reviews help, thank you!

Show Notes: https://wetflyswing.com/336 Presented By: Trxstle, Reyr Gear, Bearvault, LakeLady Custom Rods Sponsors: https://wetflyswing.com/sponsors In today's episode, we talk about fly fishing Idaho with Ed Anderson. He takes us to the McCall area in West Idaho where we touch on the Payette, Boise, and Snake rivers for rainbows, browns, and bass fishing. Find out why McCall was described as "the place of windows" and why you "have to be there to know when the windows open". We won't reveal those secret fishing spots but Ed tells us the best times to fish up there and some more useful tips. We also dig into Ed's artwork - his role being the Creative Director of West Mountain Drifters, and how he got picked up by Gray's Sporting Journal for multiple cover projects. Fly Fishing Idaho Show Notes with Ed Anderson 03:30 - Ed used to work for Jackson Kayaks - James McBeath from Jackson Kayaks was on the podcast at WFS 248 04:00 - McCall is located in Southwestern Idaho, 2 hours North of Boise, pinned between the Hells Canyon and Frank Church Wilderness of No Return - Frank Church is the largest wilderness area in the Lower 48 and Hells Canyon is the deepest Canyon in America 09:10 - The Payette and Boise rivers are Ed's home water 10:30 - The Payette and Cascade reservoirs are gigantic reservoirs - people go wakeboarding there 11:55 - Boise is now the fastest growing place in America 12:30 - Boise gets about 300 days of sunshine 13:50 - Summer is not a good fishing time in Idaho because the water level is low. Ed's favorite time to fish is when the snow is still on the ground - end of March going April. 17:05 - In Snake River, people go bass, carp, and sturgeon fishing. The largest sturgeon that was ever caught in America was in the Snake River at 117 inches 18:20 - Ed prefers the Boise over the Payette river, he says it's a more consistent cool-water fishery. August and September are Ed's preferred times to fish the Boise river because the water level stays the same for a number of days. 22:15 - On the Boise river, they get a little of the caddis hatch and primarily they're euro nymphing or streamer fishing 24:50 - Fish and Game Idaho plant steelheads in the Boise river from time to time 31:50 - Ed used to use a Coosa by Jackson Kayak 34:40 - Ed's got an Adipose skiff 35:10 - NRS Raft is a raft company from Moscow. They're coming out with a whole new line of rafts this year. 35:25 - Ed also loves Link Jackson's Stream Tech Rafts. It's a Maravia boat too. 39:50 - Ed talks about carp fishing 41:00 - Bass fishing is consistent in McCall fisheries, especially in the summer. There are some tiger muskies there too. Ed chooses bass over trout because he wants to get away from the crowd. 45:55 - Ray Troll, who is also a fish artist, was on the podcast at WFS 299 46:30 - We dig into Ed's art. You can check out his artwork on his Instagram at @edandersonart 48:20 - Ed created multiple cover artwork for Gray's Sporting Journal  49:30 - Ed and I met through Nick Torres of Waterworks Lamson. Nick had been on the podcast twice at WFS 304 and WFS 213 52:20 - Ed works with West Mountain Drifter as the Creative Director 59:30 - McCall Angler also works with Drift West  1:01:08 - Ed's go-to fly is a Yellow Sally. Fly Fishing Idaho Conclusion with Ed Anderson So there you go.. If you are from Idaho or near that area and want to enjoy some great fishing spots, you can reach out to Ed and the McCall Anglers crew. They're committed to making your experience on the water 10 out of 10. You can also reach out to Ed about artwork projects. If you need a cover art or a logo, he's the guy for you. Check out his work on Instagram at @edandersonart and send him a DM there to connect with him. Show Notes: https://wetflyswing.com/336

The NEW SOLAR HEALING room is now available to purchase, and it starts on May 15th and goes till May 21st. This will probably be our most FULL healing room; I would register sooner than later. We can only hold 100 people in these rooms—topic: Losing Weight and Removing Self Sabotaging Health Habits. You can pre-register now. My wife has lost 11 pounds in the 2.5 weeks of healing, which was done indirectly. Imagine working on this topic and things that hold you back (habits). If you want to register, here is the link: Do not use my link to share with others. Sign up first, and then you will have your own link on your dashboard to invite others so you can get credit. See you there! Here are some of the ACTIVATIONS that will take place: This activation and healing will assist with safety in losing weight. Most subconscious blocks are created to prevent the member from re-attracting the trauma created when they were at their ideal weight. We will assist all members to feel safe in losing weight; some members will notice shifts just in this activation alone. Excess Cortisol is the Number 1 Reason for obesity in the world. We will be assisting the Sympathetic and Parasympathetic systems in allowing the body to stay calm and relaxed, preventing further incurring inflammation. Also, working with different Glands of the body to secretes hormones to produce the right environment to lose weight. The Body may also have some genetic imprinting or faulty DNA, not allowing for the body to provide detox pathways to remove impurities from the body and stabilize Adipose tissue within the body. DNA imbalances will be transmitted and dismantled as we seek deeper imbalances. Working on any Energies around the Heart, Offensive attachments that could create self Sabotage, and Negative Core beliefs (present or inherited) to shift the mental image of our bodies to provide optimum Results. Included: -SEFI Frequencies sent to assist weight loss and determination: by Jessica Zevallos QLA - Meditation to assist visualization for weight loss (LOA) -Conscious Integration Video with Emanuel Zevallos CBCP, CGEF to assist with conscious ways to lose weight. - Light Activations We look forward to seeing you there! Once you are inside the group, you can invite others to join. Just look for the INVITE button on your dashboard, and you can invite people outside of HEAL and within HEAL! Happy Healing! https://network-7512321.mn.co/share/5pv3Sz3YjkHKrT-u... --- Support this podcast: https://anchor.fm/healingthehealer/support

Show Notes: https://wetflyswing.com/311 Presented By: Reyr Gear, LakeLady Custom Rods, Trxstle, Anglers Coffee Sponsors: https://wetflyswing.com/sponsors Brian Kozminski, the headman at True North Trout, is here today to shed some light on fishing streamers for brown trout. We find out the best times to go fishing in Manistee River, MI. We talk about TFO rods - Brian tells us the types of rods he uses for each season and what are his go-to flies. We learn how we can help prevent these water invasive species from spreading, which is one of our primary responsibilities as anglers, if we want to keep our waters fishable and clean. We also learn what size of native browns we can take that is actually beneficial for the fish's population system. Brian shares his story of how he once became homeless and decided to turn his life around by doing what he loves - fly fishing. Now he's on top of his game, living the life he's called for. Very powerful story! Streamers for Brown Trout Show Notes with Brian Kozminski 03:23 - Brian tells a quick story of how he once became homeless, went to rehab, then turned his life around and pursued fly fishing 06:21 - The previous owner of True North Trout wanted to retire the blog page but donated it to Brian instead 07:40 - Brian talks about the Manistee River - streamer fishing goes from April to September 09:45 - Rick Pope from TFO was on the podcast at WFS 158 10:30 - Brian shares what's coming up for him in the next couple of months 11:26 - May and June are the best times to book a fishing trip with Brian - October is great because the river gets quiet. June 21 has the longest day of the year, the sun goes down at 10:30 pm to 11 pm 16:16 - Brian walks us through Manistee River fishing (April and May) - from M72 to M66, there's a lot of 'flies only' section water in there, and bring a drift boat. Above 72, you can bring a longboat. Below 66, the river gets larger and slower 18:11 - Brian uses an Adipose drift boat 26:30 - Brian talks about mousing in July and August 30:30 - We talk about streamers in the fall - from end of August to September, they do terrestrial fishing - mid September, trout key in on cinnamon ants 31:55 - September to October, a lot of people come to Michigan to catch 25-30 pound king salmon 34:40 - Brian uses a 9 foot TFO BVO (which is now replaced by LK Legacy) fly rod during spring. During summertime, he uses a 4 wt. If he's strictly fishing streamers, the Axiom II-X is what he prefers 42:29 - Brian was on the Meat Eater show - Das Boat 49:04 - We talk about Rock Snot, aka Didymo, a type of algae - how it destroys our waters 51:08 - There are over 200 invasive species in the Great Lakes area - Brian explains how we need to take this seriously and what we can do to prevent the spread of these harmful species 55:50 - We find out what's coming up for TFO 1:08:48 - Sex Dungeon and Circus Peanut are Brian's go-to flies Streamers for Brown Trout Conclusion with Brian Kozminski Brian Kozminski sheds some light on fishing streamers for brown trout. We found out the best times to go fishing in Manistee River, MI. We talked about TFO rods - the types of rods he uses for each season and his go-to flies. We learned how we can help prevent these water invasive species from spreading if we want to keep our waters fishable and clean. We also learned what size of native browns we can take that is actually beneficial for the fish's population system. Show Notes: https://wetflyswing.com/311