Podcasts about depressing

PhenoNet Cleared By FDA To Begin Phase 3 Trial Of Inhaled Alzheimer's Drug PhenoNet has received FDA clearance to begin a Phase 3 trial of PHENOGENE-1A, an inhaled formulation of cromolyn sodium, an asthma drug with decades of safety data. Unlike most Alzheimer's therapies, which target only APOE4 gene carriers, this ~648-person trial stratifies both carriers and non-carriers by genotype, testing whether reducing amyloid aggregation, inflammation, and microglial dysfunction can benefit a broader Alzheimer's population than current treatments reach. Host Dave Asprey explains why this genotype-inclusive design challenges the field's narrow focus on APOE4 carriers, and what it means for families with Alzheimer's history who don't carry the gene. Sources: https://www.morningstar.com/news/business-wire/20260813649121/phenonet-cleared-by-fda-to-begin-phase-3-trial-of-inhaled-phenogene-1a-in-early-alzheimers-disease https://www.businesswire.com/news/home/20260813649121/en/ https://www.phenonet.us ~~~University Of Zurich Researchers Discover The Adult Brain Can Repair Itself Better Than Believed Researchers at the University of Zurich identified a population of "regenerative astrocytes" in living mouse brains that repair damaged tissue through a previously unknown mechanism: dividing cells send newly formed nuclei traveling across long cellular extensions to repopulate injured regions and rebuild the astrocyte network. The discovery overturns the long-standing assumption that adult brains have limited capacity to replace lost astrocytes after injury or autoimmune disease. Host Dave Asprey unpacks why this finding reframes brain injury recovery as something the body may already be equipped to handle, and what the newly identified genetic pathways could mean for future regenerative therapies. Sources: https://www.news.uzh.ch/en/articles/media/2026/regenerative-astrocytes.html https://www.sciencedaily.com/releases/2026/08/260812015158.htm https://www.eurekalert.org/news-releases/1139114 https://www.nature.com/articles/s41593-026-02354-5 ~~~Sheep's Wool-Derived Keratin Outperforms Collagen In Bone Regeneration Study Researchers at King's College London developed a keratin scaffold from sheep's wool, a farming industry waste product, and tested it against collagen, the current gold standard, in rats with non-healing skull defects. While collagen produced more total bone volume, the keratin scaffold generated bone that was more structurally organized and closer to natural bone architecture, while remaining stable and integrating cleanly with surrounding tissue. Host Dave Asprey explains why bone quality, not just quantity, matters for weight-bearing repair, and why a cheaper, more sustainable material outperforming the standard is a bigger deal than it sounds. Sources: https://medicalxpress.com/news/2026-04-scientists-wool-bone-material.html https://www.sciencedaily.com/releases/2026/08/260812015210.htm https://www.ivanhoe.com/news_flash/scientists-turn-sheeps-wool-into-a-material-that-helps-regrow-bone-click-here/ ~~~Oral GLP-1 Pill Aleniglipron Shows 12% Weight Loss In Phase 2b Trial Structure Therapeutics' oral small-molecule GLP-1 receptor agonist, aleniglipron, produced up to 12.1% weight loss at 36 weeks in a 230-person Phase 2b trial, with no apparent plateau and continued loss to 16% in the open-label extension, putting an oral pill in the same efficacy range as injectable GLP-1 drugs like Wegovy and Ozempic. Host Dave Asprey weighs the compliance advantage of an oral option against his ongoing concerns about muscle loss, rebound weight gain, and the fact that GLP-1 drugs treat a symptom rather than the underlying metabolic cause. Sources: https://pubmed.ncbi.nlm.nih.gov/42249138/ https://www.nature.com/articles/s41591-026-04476-6 https://ir.structuretx.com/news-releases/news-release-details/structure-therapeutics-announces-publication-nature-medicine/ https://www.fiercebiotech.com/biotech/structure-touts-16-weight-loss-aleniglipron-highest-efficacy-oral-glp-1 ~~~Study Finds 150 Minutes Of Weekly Exercise Falls Far Short Of Real Heart Protection A Macao Polytechnic University analysis of over 17,000 UK Biobank participants found that the standard 150-minute weekly exercise guideline only reduces cardiovascular risk by 8-9%, while achieving a substantial risk reduction of over 30% requires 560-610 minutes a week, three to four times current recommendations. Only 12% of participants hit that higher threshold. Host Dave Asprey breaks down why public health minimums are a floor, not an optimization target, and what listeners serious about cardiovascular protection should actually be aiming for. Sources: https://medicalxpress.com/news/2026-05-real-heart-weekly-climbs-current.html https://www.medicalnewstoday.com/articles/560-610-minutes-weekly-exercise-lower-cardiovascular-risk-heart-health https://bjsm.bmj.com/content/early/2026/05/19/bjsports-2025-111351 ~~~New Research Clarifies The Mechanism Behind IV Vitamin C's Anti-Cancer Effect Decades after Linus Pauling's high-dose vitamin C claims were dismissed following failed oral-dose trials, researchers have clarified that Pauling had the mechanism right and the delivery method wrong: IV vitamin C bypasses gut absorption limits to reach plasma concentrations up to 100 times higher than oral dosing, generating hydrogen peroxide that is selectively toxic to cancer cells due to their lower catalase levels. A 2024 University of Iowa study found IV vitamin C combined with chemotherapy doubled overall survival in advanced pancreatic cancer patients. Host Dave Asprey reflects on how this vindicates a decades-old idea that was dismissed for the wrong reasons, and what it means for anyone facing a cancer diagnosis. Sources: https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2018.01182/full https://www.cancer.gov/about-cancer/treatment/cam/hp/vitamin-c-pdq https://medicine.uiowa.edu/news/2024/11/high-dose-iv-vitamin-c-plus-chemotherapy-doubles-survival-advanced-pancreatic-cancer This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want the latest breakthroughs in neurodegenerative disease, regenerative medicine, metabolic health, and cancer therapeutics, translated into what actually matters for your biology right now. Host Dave Asprey connects clinical trial data, mechanistic research, and decades of context into practical frameworks for taking control of your own health decisions. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: PhenoNet PHENOGENE-1A, inhaled cromolyn Alzheimer's, APOE4 genotype Alzheimer's trial, regenerative astrocytes brain repair, University of Zurich brain regeneration, adult neuroplasticity, keratin bone scaffold, sheep's wool regenerative medicine, collagen vs keratin bone repair, aleniglipron oral GLP-1, Structure Therapeutics weight loss drug, oral semaglutide alternative, exercise minutes cardiovascular risk, 150 minutes exercise guideline, Macao Polytechnic University heart study, IV vitamin C cancer, Linus Pauling vitamin C, ascorbate hydrogen peroxide cancer cells, integrative oncology, biohacking news 2026, Thank you to our sponsors! - Visit www.myvitalc.com/davesfav to unlock Dave's discount - Neuronic | Go to www.neuronic.online Code DAVE for $100 off - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Alzheimer's Drug Trial 01:43 – Brain Repair Cells 03:07 – Keratin Bone Scaffolds 04:45 – Oral GLP-1 Pill 05:59 – Minimum Effective Exercise 07:26 – IV Vitamin C Revisited 08:12 – Vitamin C Cancer Trial 09:30 – Takeaway See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Trade Deadline is Monday. Will the Pirates make a move? Camilo Doval already acquired. What kind of answer is this? We'll talk about it. Depressing series in Cincinnati. https://linktr.ee/bridgetobuctoberSEE THIS VIDEO FOR A CHANCE TO WIN A PAUL SKENES BOBBLEHEAD!https://youtu.be/NXULahD52UsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The Fangirls start off the second half of the season with a bang as they welcome BookTuber and debut author Cindy Pham to chat about her debut novel, THE SECRET WORLD OF BRIAR ROSE! Stay up to date with Cindy by visiting her website.Click here to read the extended show notes, which includes where to find a list of all the books mentioned in this episode, how to contact us, where to find us on social media, how to support the show and The Fangirls, and all our internet besties and associated coupon codes: http://theincoherentfangirl.com/show-notes

Aston Villa have sold midfielder Morgan Rogers to Chelsea for a whopping £117m. Where does he fit in to the Stamford Bridge project, and where does this leave Villa in terms of midfield options? It is one of the biggest fees in British history, but also, where do these giant deals stop? We get deep on today's episode as we ask whether the financial landscape in the Premier League is good for the health of the game in this country. SUBSCRIBE NOW: ⁠https://footballsocialdaily.supportingcast.fm/⁠NEW: Instagram: ⁠https://www.instagram.com/fsdpod?igsh=MjQ5d29veGdoMmZ4&utm_source=qr⁠ Twitter: ⁠https://twitter.com/FSDPod⁠ TikTok: ⁠https://www.tiktok.com/@footballsocialdaily⁠ Telegram Group: ⁠https://t.me/FootballSocialMerch Store: https://www.etsy.com/uk/shop/FootballSocialDaily Learn more about your ad choices. Visit podcastchoices.com/adchoices

Megan had no idea what was coming when Colin Fassnidge and Manu Feildel arrived to sample her daily homemade pancakes. The celebrity chefs didn't hold back with their feedback, delivering some savage reviews! They also share stories from filming, travelling New Zealand, and why Kiwi food and produce impress them so much. Join the Itty Bitty Hitty Committee HERE!Instagram: @THEHITSBREAKFASTFacebook: The Hits Breakfast with Jono, Ben & MeganSee omnystudio.com/listener for privacy information.

NBA fanbases that are always down bad! #nba   Check out the TD3 merch: https://the-deep-3-shop.fourthwall.com/   Listen on Spotify!: https://open.spotify.com/show/3elbbqVumwqz8wlIdknsLW   Listen on Apple Podcasts!: https://podcasts.apple.com/us/podcast/the-deep-3-podcast/id1657940794   Follow us on TikTok!: https://www.tiktok.com/@thedeepthree   Follow us on Instagram!: https://www.instagram.com/thedeep3podcast/   Isaac's twitter: https://twitter.com/byisaacg   Mo's twitter: https://twitter.com/Mojo99_   Donnavan's twitter: https://twitter.com/Dsmoot3D Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Paul followed through on his promise to read Fathers and Sons by Turgenev, Paradise Lost, and Crime and Punishment to discuss with a former student. Some gleanings from his particular corner of the asylum.

From Caroline Calloway penning viral essays to the constant discourse surrounding Ariana Grande - it's no news to listeners of this podcast that thin is in. Yet on a weekly if not daily basis, a new Internet fixation surrounding weight loss rears its ugly head. The content is impossible to avoid, but in a culture that is normalising extreme thinness more and more, is it any wonder how we got to this point?This week, hosts Ione and Gina dig into the proliferation of not just skinniness but pro-ana rhetoric, and whether we will ever return from the ongoing requirement of extreme restrictions in women.Trigger warning: This week's podcast discusses eating disorders and weight loss and may be triggering for some readers.Order The Polyester Book Of Bad Taste here!Support our work and become a Polyester Podcast member

Host & former MTV VJ Matt Pinfield tells Shout It Out Loudcast his thoughts on "Down In A Hole" by Alice In Chains and how its "Depressing As Hell!" To Purchase Shout It Out Loudcast's KISS Book “Raise Your Glasses: A Celebration Of 50 Years of KISS Songs By Celebrities, Musicians & Fans Please Click Below:   ⁠⁠Raise Your Glasses Book⁠⁠   For all things Shout It Out Loudcast the #1 KISS Podcast check out our amazing website by clicking below:   ⁠⁠www.ShoutItOutLoudcast.com⁠⁠   Interested in more Shout It Out Loudcast content?  Care to help us out?  Come join us on Patreon by clicking below:   ⁠⁠SIOL Patreon⁠⁠   Get all your Shout It Out Loudcast Merchandise by clicking below:   ⁠⁠Shout It Out Loudcast Merch At Printify⁠⁠   Shop At Our Amazon Store by clicking below: ⁠⁠Shout It Out Loudcast Amazon Store⁠⁠   Please Email us comments or suggestions by clicking below: ⁠⁠ShoutItOutLoudcast@Gmail.com⁠⁠   Please subscribe to us and give us a 5 Star (Child) review on the following places below: ⁠⁠iTunes⁠⁠ ⁠⁠Podchaser⁠⁠ ⁠⁠Stitcher⁠⁠ ⁠⁠iHeart Radio⁠⁠ ⁠⁠Spotify ⁠⁠   Please follow us and like our social media pages clicking below: ⁠⁠Twitter⁠⁠ ⁠⁠Facebook Page⁠⁠ ⁠⁠Facebook Group Page Shout It Out Loudcasters⁠⁠ ⁠⁠Instagram⁠⁠ ⁠⁠YouTube⁠⁠   Proud Member of the Pantheon Podcast click below to see the website: ⁠⁠Pantheon Podcast Network⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Where you Live and Work...Depressing or Inspiring? Have you created an environment that inspires you to be healthy, fit, strong and happy? If NOT, is it time to move/UPROOT yourself? You are not a tree – You can move!!

The new Zul'jan quest line just went live, so we're looking forward to World of Warcraft patch 12.1, which includes a new Player Housing exterior. Maybe. We hope. And we're not Monkey's Paw-ing this thing either, so don't act like we said it and that's why it's on the store. We already firmly rejected that possibility, so it is not on us if it goes down like that.Speaking of Monkey's Paws, Summer Games Done Quick is live, and Microsoft took that as a challenge, seeing if they could finish games as a whole really quickly by firing 20% of Xbox employees. This included closing many iconic game studios, some of which are going independent (again), and some being bought out by another party. There are some silver linings here, but it's a tough summer for people who make or enjoy games.A new Hearthstone expansion also released this week, so we have the lowdown on Escape from Violet Hold. It involves a jailbreak and Vanessa Van Cleef, so we're going out on a high note.If you have a few minutes, please fill out our survey to tell us what you think about the podcast. This data is collected by our podcast host, Acast, and will be used to help us improve the show as well as attract potential sponsors. Your answers are completely anonymous. We appreciate your help!If you enjoy the show, please support us on Patreon, where you can get these episodes early and ad-free! Hosted on Acast. See acast.com/privacy for more information.

Donna & Steve open the show talking about upcoming celebrity pairings for Who Wants to Be a Millionaire, you can bid on Colonel Sanders memorabilia and do you have any "weak-tie" relationships?In hour two, we play the Soap Opera edition of the College of Pop Culture Knowledge, Rick Springfield looks shredded at 76 and why you should always wash your hands after touching these three things.Finally, Anthony Hopkins signed a record deal, the best travel & leisure cities in America and we find out the Soup of the Day!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, we meet Simon, a 51-year-old former Jehovah's Witness who was born into the organization during the height of the 1975 end-times hysteria. Growing up in a "biosphere of fear" in Quebec, Simon recounts a childhood defined by apocalyptic imagery, Holocaust-themed propaganda, and the intense pressure to conform to a "misfit" family dynamic that prioritized religious survival over individual identity. He takes us through his formative years—from his baptism at 17 to a 25-year marriage that ultimately dissolved when his pursuit of truth collided with the organization's rigid demand for loyalty. The narrative reaches a turning point when Simon confronts the systemic rot within the organization, including the discovery of an elder who had assaulted 22 women in a single congregation, only to be reinstated and sent to Simon's home. Simon discusses the specific mental health toll on men within the Watchtower, describing a "treadmill" of performance that leads to chronic depression and emasculation. Now living authentically after a pivotal sabbatical in Mexico, Simon shares how reclaiming his voice and listening to his "inner voice" led to a life of peace, clarity, and deep connection with his daughter, who also escaped the group. Key Takeaways The "North Star" of Truth: Simon explains that the very tools the organization gave him—a high respect for "The Truth"—eventually became his way out once he began to apply critical thinking and honest research to the group's own history and policies. Institutional Betrayal and Safety: A major catalyst for Simon's exit was the organization's failure to protect its members, highlighted by the "prolific" scandal of a predatory elder whose crimes were overlooked while the victims remained unprotected. The Psychological Treadmill for Men: Simon highlights the unique burden on men to be "beta males" who are compliant and self-sacrificing, which often results in a chronic loss of agency and deep-seated depression. The Body Knows: Simon encourages those in high-control groups to pay attention to physical symptoms—such as anxiety, depression, or a "lack of peace"—as these are often the body's way of demanding to be heard when the mind is being gaslit. "Who's on My Bench?": Through his disassociation letter, Simon found clarity by forcing his social circle to take a stand, allowing him to distinguish between superficial, conditional connections and real, solid relationships. Direct Quotes "Reality wins. You know, like you can keep your head in the sand and have your delusions and hang on tight to them, but you know, the longer it goes on, the higher the consequences… and in the end, reality wins." "If I could encourage anybody out there that's questioning… listen to your body and what it's telling to you… your body will demand to be heard sooner or later." "I needed to know going into the third period of my life who's on my bench and who's not… I don't have any more resources, time, attention, space for shallow relationships." Resources Mentioned ExJwHelp.com (Cult recovery coaching and resources) RAADS-R test (Screening tool related to autism and social interaction) Shunned Podcast (Lived experience and deconstruction episodes) Insight on the Scriptures and Bound Volumes Revelation—Its Grand Climax at Hand! (The "Revelation book") Australian Royal Commission (ARC) Disentangling from Emotionally Immature People (Book) ExJW subreddit (Reddit community) This JW Life (The host's original podcast story) Becoming Jehovah (Free online book by the host) patreon.com/shunned (Bonus content and guest connections) Guest Bio Simon is a 51-year-old former third-generation Jehovah's Witness and father who reclaimed his agency after five decades in a high-control environment. Now a self-employed professional, he focuses on living a life of peace and clarity while advocating for the importance of mental health and self-validation for those recovering from religious trauma. Support the show and get bonuses as well by donating to the cause on our Patreon page, Patreon.com/shunned Are you struggling in some area of life? Feeling stuck? Need an accountability partner or some encouragement? Need to talk to someone that understands cult life? Reach out and let's talk. I have affordable programs to help as a certified life coach with a focus on cult recovery. Click HERE for more information. Want more resources? Go to my other website exjwHelp.com Leave us a review on iTunes Find shunned podcast on Youtube, including new VIDcasts here. Follow us on Twitter and Instagram. You can listen to the Shunned Podcast Spotify playlist here for all of the songs chosen by guests of the show. This podcast was made possible by my original podcast This JW Life. You can find it on any podcast app. It is a 9 part series about life as Jehovah's Witnesses designed to help you understand how it worked in one comprehensive story and to help you process your own if you came from that environment. Read my FREE online book, based on This JW Life, called Becoming Jehovah, in both English and Spanish by clicking here An ExJW podcast and ExJW YouTube Channel

The Steve Harvey Morning Show for Tuesday June 30th, 2026: Steve Harvey's Morning Inspiration | Show Open - Intros | Nephew Tommy's Run That Prank Back - "Bump & Grind" | Ask The CLO | Depressing Places | Would You Rather | Should Party Guests Help Clean Up? | Nephew Tommy's Prank - "PSC - Prostate Checker" | Strawberry Letter - "He Knew He Married A Black Woman" Pt. 1-2 | Ask Steve | Social Media Advice | Would You Leave Your Marriage For $10M? | Would You Rather | Steve Harvey's Closing RemarksSupport the show: https://www.steveharveyfm.com/See omnystudio.com/listener for privacy information.

Steve Harvey Morning Show Online: http://www.steveharveyfm.com/See omnystudio.com/listener for privacy information.

A massive new missing-child mystery miniseries has officially hit streaming, and it is full of the high-stakes legal drama we love. With a beloved television heartthrob making a very good-looking appearance as a helpful billionaire, you will be completely hooked from the very first episode.Plus, one of the biggest and most highly anticipated movies of the year has finally dropped on a major streamer. Its a whimsical, star-studded book adaptation, packed with laugh-out-loud comedy, distinct fluffy characters, and an unexpectedly touching message about processing grief.Remember The Spill drops the tea twice a day in this feed so follow us for all the latest entertainment news OR you can WATCH our show in full length video on the Apple Podcast app - make sure your phone is up to date and enjoy the watch! Link here. THE END BITS Find and follow us on socials: Instagram: https://www.instagram.com/thespillpodcast/ TikTok: https://www.tiktok.com/@thespillpod Facebook: https://www.facebook.com/thespillpodcast/ Read all the latest entertainment news on Mamamia: https://mamamia.com.au/entertainment/ Support independent women’s media and get our biggest offer of the year. Subscribe here for 30% off your annual Mamamia subscription. Code applied at the checkout. Offer ends June 30. Your subscription helps us continue to tell the stories that matter to women. Want to join the conversation? Have feedback or a topic you want us to discuss? Send us a voice message or email us at thespill@mamamia.com.au and we’ll get back to you ASAP! Executive Producer: Monisha Iswaran Audio & Video Producer: Michael Kean Mamamia acknowledges the traditional owners of the land on which we have recorded this podcast.Become a Mamamia subscriber: https://www.mamamia.com.au/subscribeSee omnystudio.com/listener for privacy information.

Grant & Danny debate which D.C. Sports losses broke their heart the most.

Welcome to Media Club Plus: a podcast about diving into the media that interests us and the stories that excite us. This season we're watching The Sopranos. In this episode, we watched episodes 3 and 4: Denial, Anger, Acceptance and Meadowlands. Next episode we're watching episodes 5 and 6: College and Pax Soprana. Featuring Keith Carberry (@KeithJCarberry), Sylvi Bullet (@SYLVIBULLET), Arthur Martinez-Tebbel (@amtebbel), and Andrew Lee Swan (@swandre3000) Produced by Keith Carberry Music by Jack de Quidt (available at notquitereal.bandcamp.com) Cover Art by by Annie Johnston-Glick (@dancynrew) anniejg.com You can find the screenshot post here This episode was made with support from listeners like you! To support us, you can go to http://friendsatthetable.cash

From a 24-hour hangover and the pure joy of a clean garage to campaigning for the return of the mixtape (Spotify playlists just aren't the same), Wells is showing his age again in today's episode. And after weeks of YFTers begging, Brandi FINALLY started Off Campus! The excitement continues as Wells shares that he got to film his golf show with the legendary Luke Wilson, where he discovers Luke's favorite Wes Anderson movie (not the one you'd expect) but somehow forgets to ask about The Family Stone. A devastating fumble. Meanwhile, Brandi spends her week h anging with all the dogs at Wags & Walks and accidentally spills the tea on a secret Cyrus family pet (and it's not the tortoise or the ducks!). Plus, they discuss the deeply upsetting Netflix documentary The Crash, the never-ending Murdoch family drama, and a book recommendation featuring aliens and a cat named Princess Donut. Please keep those DMs coming because we love hearing from you! Favorite Things: (18:37) Off Campus (22:38) The Crash (25:32) Instadocs: Alex Murdaugh, Unconvicted, (26:24) Dutton Ranch (SPOILERS) (27:01) Dungeon Crawler Carl by Matt Dinniman (Book)(29:42) Ladies First (33:14) The Burroughs (34:21) Four Seasons Thank you to our awesome sponsors: Article: Article is offering our listeners $50 off your first purchase of $100 or more. Visit article.com/discount/yft and the discount will be automatically applied at checkout. BetterHelp: You don't have to say yes to everything this summer. Find support in therapy. Sign up and get 10% off at BetterHelp.com/yft. First Leaf: Stop settling for wines that don't quite hit the mark. Head to TryFirstleaf.com/YFT to sign up and you'll get 50% OFF your first box PLUS free shipping for an entire year. Hers: Ready to reach your goals? Visit forhers.com/yft to get personalized, affordable care that gets you. Quince: Go to Quince.com/yft for free shipping on your order and 365-day returns. Now available in Canada, too! Zazzle: Right now, save 25% on your first order at Zazzle.com. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

us too Megyn, us toowatch the full podcast - https://www.youtube.com/watch?v=9W6gxWycbVABecome a Member and Give Us Some DAMN GOOD Support :https://www.youtube.com/channel/UCX8lCshQmMN0dUc0JmQYDdg/joinGet your Twins merch and have a chance to win our Damn Good Giveaways! - https://officialhodgetwins.com/Get Optimal Human, your all in one daily nutritional supplement - https://optimalhuman.com/Want to be a guest on the Twins Pod? Contact us at bookings@twinspod.comDownload Free Twins Pod Content - https://drive.google.com/drive/folders/1_iNb2RYwHUisypEjkrbZ3nFoBK8k60COFollow Hodgwtins Podcast Everywhere -X - https://x.com/hodgetwinspodInstagram - https://www.instagram.com/hodgetwinspodcast/Facebook - https://www.facebook.com/thehodgetwinsYouTube - https://www.youtube.com/@HodgetwinsPodcastRumble - https://rumble.com/c/HodgetwinsPodcast?e9s=src_v1_cmdSpotify - https://open.spotify.com/show/79BWPxHPWnijyl4lf8vWVuApple - https://podcasts.apple.com/us/podcast/hodgetwins-podcast/id1731232810

Lords: Lena Cory Topics: Re: Cory's teeth topic, there's so many artists making teeth It would actually rule to be immortal, and all those stories about how it's not are just cope How committed to the bit is committed to the bit enough? A poem by Evan Balster, shared with us at GDC: A shapeless figure, locked away Inside a realm she godly sways; To weave in light and shadow, there, A living, breathing world from air. And nightly does she host a guest Who comes and goes at own behest, And time to time might take the throne To make the place a toy his own And on the morn to leave the mess Its keeper cleans, without protest. For lonely is the weaving-hand, The breaking-one's its only friend. Microtopics: Topic Lords-themed hangouts. Indie City Games. Two Truths and a Lie, a science fiction detective story. A disgusting old man using an army of combat drones to find out what happened to his ex-boyfriend. Two topics for the price of one. Tooth dreams. Considering what to do about your teeth as you go through various phases of having or not having teeth. What people say if your femur is yellow. People dying from mouth problems. Going to the tooth artists and customizing your new teeth, just like Build-a-Bear. Reaching into your mouth and pushing the button on your artificial tooth that plays your catchphrase. The artist who illustrates your subject in stages as you dissect it. Illustrating gross health things in a way that people can understand. The cartoon amoeba that teaches you how to not get salmonella. The kind of people who comment on Fecal Transplant Explainer videos. Teeth: you chew with them. Hitting up your dentist for extra teeth because the last ones were delicious. The thing you have in your mouth the most that you're not allowed to eat. (Your teeth.) Gradually eating your own teeth because you grind your own teeth at night. Different sets of dentures for different vibes. How to get glow in the dark teeth. Discovering the hard way that your fake teeth don't fluoresce under UV light. An entire generation of Americans going into the dentist together, like Hands Across America, to get all their teeth pulled so they can get dentures. Losing all your teeth just in time for COVID. Learning to not feel like you have to explain why you don't have any teeth. Depressing people with possible existences that your mind can create. What to do with the people who get too old to have good opinions. Trying to maintain a continuous personality day to day. Immortality vs. just living a really long time. Burning it all down for the sake of your legacy. Continuing to try to save people's lives and eventually inventing immortality. Death: it's really cool actually. Coming face to face with death and realizing it's not scary at all. A Satanist and his wife selling everything to open a shop where they refuse to sell you human skulls and serial killer memorabilia. Not needing a Memento Mori room because you already think about death all the time. Transferring a marble from the future jar to the past jar to remind yourself not to waste this day. Having a child and tossing it on the pile of existing children that everyone's already taking care of. All there is to learn in the universe. The Sword in the Stone. Working all of physics out from first principles because it's fun and you have that kind of time. Deciding to spend 100 years just hanging out with a tree and you don't even have podcasts. Icehenge. Associated Press title capitalization rules. A decision that is awesome for everything except your wallet. Artists who don't like what they make and don't enjoy the process, they just have to do it. Not doing art for long enough to realize how unhappy you are because you're not doing art. Making games because it's cool and fun to make games. Making yourself happier by pretending to be happy. What's bad about being too happy? Oh thank God, a crisis! A series of dreams in which the dream world is aware of you and hates you. Lonely is the weaving hand, the breaking one its only friend. Why you should be grateful when your son throws his trash on the floor. The most mystical thing that we get to regularly experience. Déjà rêvé. One of the worst ways to determine whether you're dreaming. Morpheus refusing to explain the Matrix in words even though he could describe it in 30 seconds. Spoilers: the events of Inception did not actually occur.

Conor Sheehan, Labour Party housing spokesperson, reacts to the latest Daft.ie Rental Report.

HOUR 4: Are zoos actually kind of depressing? full 1993 Mon, 18 May 2026 22:00:00 +0000 b8zHOEX4luDCiHSYTOKOz106OXNVmxgN news The Dana & Parks Podcast news HOUR 4: Are zoos actually kind of depressing? You wanted it... Now here it is! Listen to each hour of the Dana & Parks Show whenever and wherever you want! © 2025 Audacy, Inc. News https://player.amperwavepodcasting.com?feed-lin

Join the Bruins Benders Podcast as they cover the HOTTEST topics in the Boston Bruins market, along with... Charle Jacobs says the team is on the right track? Huh? Cam Neely admits the team needs speed and skill, what happened to piss and vinegar? Don Sweeney says player development hasn't been a failure. Wait. What? Providence Bruins out of the playoffs early, again. Connah's Cornah, On A Bender & Much More! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

If you want to know why youth in America are struggling to move from renting to home ownership, then look no further than the Covid years. As one housing expert says, Covid became the pivot point in the nation where building homes turned into a developer's nightmare, because pricing homes was so impossible. And that challenge was passed right along to consumers. The effects still linger.

Listen to today's Laugh Again with Phil Callaway, "Depressing Nursery Rhymes." Enjoy!

Is your house depressing? We are here to help you make it a happy place. Let's talk about the things that might be making your home feel sad.For starters, make sure you have good lighting and you've decluttered your home.Kelly's App - Home Design Coach is fantastic! Have you checked it out? Right now save 20% and have Kelly help you design a home you truly LOVE! Go HERE to see what it is all about and subscribe. The special launch pricing ends on May 8th - don't miss out!Crushes:Anita's crush is a set of these clear plastic bins she uses in her pantry HERE.Kelly's crush is the new patterned made to measure rugs by Ernesta. See the collection HERE.Need help with your home? We'd love to help! We do personalized consults, and we'll offer advice specific to your room that typically includes room layout ideas, suggestions for what the room needs, and how to pull the room together. We'll also help you to decide what isn't working for you. We work with any budget, large or small. Find out more HERECheck out Anita's Amazon shop HERE.Are you subscribed to the podcast? Don't need to search for us each Wednesday let us come right to your door ...er...device. Subscribe wherever you listen to your podcasts. Just hit the SUBSCRIBE button & we'll show up!XX,Anita & KellyDI- 11:05 / 18:39See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The boys drink and review "Fried Salad," a dry-hopped oat lager from Tactical Brewing Company in Orlando, then dive into the world of national parks.They start with a little history: from Yellowstone's establishment under Ulysses S. Grant in 1872, to Theodore Roosevelt's conservation legacy, to the National Park Service itself. Then they take a tour through Maryland's 15 national park sites before turning their attention to the roughly 20 parks and monuments designated in recent years under the Biden administration.What do the new designations have in common? The guys break them down one by one — from Bears Ears and the Grand Canyon expansion to the Harriet Tubman Underground Railroad site, the Harvey Milk National Historic Site, the Pullman National Historic Park, and the Emmett Till Monument — and share their take on what the trends say about how America chooses to remember itself.A wide-ranging, honest conversation about conservation, history, national identity, and whether the park system should make you feel proud — or guilty.

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It’s the end of the world, again. This time the hosts are like the two worlds slowly colliding while they discuss this 2011 drama. Depressing, isn’t it? Promo: Monsterkid Radio (http://www.monsterkidradio.net) Please click, follow, rate and review! https://linktr.ee/TSPandOE_Podcasts

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Listen below or click here for full show notes Main Mission, Part 1 (with an appropriate sound effect) Starfleet Academy cancelled Star Trek: Starfleet Academy EP Confirms Season 2’s Major Risk ‘Star Trek: Starfleet Academy’ Canceled After Two Seasons Why Paramount Plus Ended Star Trek: Starfleet Academy After Two Seasons Star Trek: Starfleet Academy Ending With Season 2 Breaking — STAR TREK: STARFLEET ACADEMY Ends with Season 2, Wrapping Known Kurtzman-Era Productions – TrekCore.com ‘Star Trek: Starfleet Academy’ To End With Season 2 At Paramount+ ‘Star Trek: Starfleet Academy’ to End With Season 2 (EXCLUSIVE) William Shatner Speaks Out After Starfleet Academy’s Cancellation: ‘That Aspect Of Star Trek I’ve Always Loved’ William Shatner Breaks Silence on Surprise ‘Star Trek: Starfleet Academy’ Cancelation – Men’s Journal Paramount+ Is Dismantling Star Trek After a Historic 9-Year Streaming Run Star Trek is Adrift: Why ‘Starfleet Academy’ is Folding After Season 2 The Real Reason for Paramount Dismantling Star Trek’s 9-Year Streaming Run Isn’t What You Think David Ellison On Cost Savings, Growth, The Tech Stack & AI As WBD Merge Star Trek: Starfleet Academy Cancellation Explained By Robert Picardo These 7 Rumored ‘Star Trek’ Shows Could Save the Franchise After ‘Starfleet Academy’s Cancelation The Star Trek Series Decades In The Making Lasted Just Over 2 Months Why Starfleet Academy's Cancelation Has Me Worried About The Star Trek Franchise ‘Star Trek: Starfleet Academy’ Offers the Franchise a Unique Way Forward STAR TREK’s TV Future Explained by Alex Kurtzman Amid Paramount Skydance Changes — GeekTyrant Subspace Chatter STAR TREK: YEAR ONE Has Already Been Pitched To Paramount Skydance STAR TREK: YEAR ONE Pitch Has Officially Reached Paramount Skydance -CBR “Star Trek: Year One” Has Been Pitched – Dark Horizons Star Trek: Starfleet Academy Fan Petition Hits Milestone After Paramount+ Cancellation Petition · Renew ‘Star Trek: Starfleet Academy' for a third season – United Kingdom · Change.org Star Trek: Scouts Final Episodes Released on YouTube Star Trek: The Next Generation Star Remembers When They Weren’t Real Trek | Den of Geek NickALive!: The 16th Anniversary Bundle! | Star Trek Online 25 Years Later, Star Trek Has Revealed The Hidden Reason Starfleet Actually Began PREVIEW — Inside IDW's THE ART OF STAR TREK: LOWER DECKS – TrekCore.comAndy Weir Apologizes To Alex Kurtzman After Slamming Modern STAR TREK ‘Project Hail Mary' Author Stirs Controversy Over Failed Star Trek Pitch, Then Apologizes To Alex Kurtzman – TrekMovie.com Andy Weir ‘Star Trek’ Comments Draw Fire From Author Don Winslow ‘Star Trek’: How The Beatles Inspired Kirk and Spock's Reboot Bond Leonard Nimoy’s Positive Reaction To Star Trek: DS9’s ‘Trials and Tribble-ations’ Star Trek: Prodigy Wins Emmy Award Land The Shuttlecraft Galileo by Brian Mix — Kickstarter STAR TREK: STRANGE NEW WORLDS Season 4 Premiere Expected In Late Summer Toy Fair ’26: Nacelle announces Lucille Ball & Gene Roddenberry action figures Action Figure Insider » Nacelle Toys Reveal New Star Trek Products at #Wondercon2026 Here are links to 57  additional stories.broken out by series, movies and other categories. CLASSIC TV SERIES (in order of premiere) Star Trek: The Original Series (1966 – 1969) [3 seasons] 57 Years Ago Today, Star Trek Released A Time Travel Masterpiece That The Franchise Has Never Beaten – ComicBook.com ‘Star Trek' Actress Admits She Had a Crush on William Shatner Star Trek: The Next Generation (1987 – 1994) [7 seasons] 10 Star Trek: The Next Generation Episodes To Skip On A Rewatch Star Trek: TNG’s Chain of Command Is Mandatory Viewing for Every Sci-Fi Fan Star Trek: Deep Space Nine (1993 – 1999) [7 seasons] One Of Star Trek's Best Episodes Was Created Out Of Spite Star Trek: Voyager (1995 – 2001) [7 seasons] The Star Trek Episode That Only Exists Because Of A Sex Joke STREAMING SERIES AND MOVIES (in order of premiere) Star Trek: Picard (2020 – 2023) [3 seasons] Why 1 Returning Star Trek: The Next Generation Star Was Disappointed by Picard Season 3's Reunion – ComicBook.com ‘Star Trek: Picard’ Never Confirmed ‘Voyager’s Alternate Future Captain La Forge Reveal Star Trek’s Marina Sirtis Explained Why Comparing Her Experience On Picard Season 3 To TNG Was ‘Depressing’ | Cinemablend Star Trek: Lower Decks (2020 – 2024) [5 seasons] Star Trek: Lower Decks Made An Abandoned Vulcan Character Franchise Canon Star Trek: Strange New Worlds (2022 – present) [4th season yet to premier, 5th/final season filmed] Star Trek director ‘was very proud of’ arguably the worst Strange New Worlds episode STAR TREK: STRANGE NEW WORLDS Season 4 Promises “Classic” Episodes Alongside Bold New Experiments Star Trek: Starfleet Academy [2026 – present] [season 2 will end series] Star Trek Officially Confirms It Now Follows One of the Oldest Star Wars Rules – ComicBook.com Starfleet Academy Showrunner Teases Season 2: ‘The Dynamics You Thought Were Going to Be One Way Forever Start to Slowly Shift' – IGN REVIEW – Star Trek: Starfleet Academy “Rubincon” – Trek Central Starfleet Academy is Star Trek (despite what so-called fans would have you believe) Star Trek's Most Divisive Spin-Off Warps Past a Major Streaming Milestone Starfleet Academy's Finale Improved Because It Removed Terrible Star Trek Characters Star Trek: Starfleet Academy season 1 finale provides 6 unexpected glimpses of the future Star Trek: Starfleet Academy Is The Greatest Argument For The Return Of Long TV Seasons Yes, There Will Be a Starfleet Academy Season 2. Here’s What We Know About It – Reactor KUOW – ‘Starfleet Academy’ isn’t for everybody, but ‘Star Trek’ still is (Did ‘Star Trek’ jump the targ?) 39 Years Later, The Star Trek Franchise Just Put Itself On Trial — Again Jonathan Frakes Reacts to ‘Absurd’ Star Trek: Starfleet Academy Gag The United Federation of Planets Has a War College Now — Are We Gonna Talk About It? – Reactor Star Trek just fumbled what could have been an all-time villain reveal Star Trek: 3 Best Things About Starfleet Academy Season 1 (& The 5 Worst) – ComicBook.com Starfleet Academy season 1 finale makes it painfully obvious what's coming for the Doctor in season 2 Star Trek: Starfleet Academy Calls Out a Missing Piece of Starfleet Canon 60 Years Later Star Trek actor was Jonathan Frakes’ ‘secret weapon’ on Starfleet Academy Star Trek icon praises Starfleet Academy’s ‘great’ Khionian actor unannounced “Star Trek: Legacy” series Star Trek: Legacy Is ‘Never Gonna Happen’ Says TNG Icon Trek series that never were, for one reason or another, [such as “Phase II”] The Lost ‘Star Trek' Movies and Shows That Almost Happened—and the Stories Behind Them THEATRICAL MOTION PICTURES (in order of premiere) Star Trek: First Contact (1996) Tom Hanks Wanted To Play An Extremely Important Star Trek Character Fourth Kelvin-timeline movie [cancelled in 2025 after many false starts] Why Star Trek 4 Isn't Happening OTHER MEDIAStar Trek video games/board games We Boldly Go Hands-On With Star Trek: Infection & Live To Tell About It Star Trek toys/collectibles/other merchandise March STAR TREK Merch Roundup: Klingon Weapons, STARFLEET ACADEMY Pins, New EXO-6 Figures, and More! – TrekCore.com Star Trek Comics/graphic novels/magazines Star Trek: The Last Starship #8 Exclusive Preview Star Trek: The Last Starship #6 – Comic Book Preview MISCELLANEOUS Paramount+ / Paramount Skydance David Ellison On Cost Savings, Growth, The Tech Stack & AI As WBD Merger Star Trek related science news A Modest Proposal: Star-Trek-like Communicator Badges for Siri | Scientific American Franchise-wide/Miscellaneous All 10 Star Trek Series Finale Episodes, Ranked – AOL All 14 Star Trek Movies Ranked According To Rotten Tomatoes Paramount has a Star Trek Strategy Problem. Here Are Five Ways to Fix It. 10 essential Star Trek episodes to watch after Starfleet Academy season 1 Every Star Trek First Season Ranked Worst to Best – Reactor Everything We Know About the Future of ‘Star Trek’ Column | What ‘Star Trek' teaches us about the 21st century – The Pitt News Rod Roddenberry on Carrying Forward the STAR TREK Legacy – Nerdist The 10 Best Star Trek Episodes of All Time – ComicBook.com Where did ‘Star Trek’ go? And what does it mean for the future of Paramount – and movie theaters? – East Idaho News 10 Most Uncomfortable Star Trek Scenes Of All Time Star Trek Should Boldly Go Back To Network TV ‘Star Trek: The Next Generation’ Trivia: Take the World’s Hardest Quiz Actor Watch Jonathan Frakes Says STARFLEET ACADEMY Could Be His Last Time Directing STAR TREK — GeekTyrant Shatner's 95th sparks global Star Trek party Shatner Reveals Why He Avoids Watching Star Trek Main Mission, Part 2 (with an appropriate sound effect) Star Trek: The Cruise 2026 End Of Show It’s about time to refill the dilithium chamber and get on out of here. Find Clinton at Comedy4Cast Find Chuck and Kreg at Technorama Podcast (MUSIC IN) If you liked the show, please be sure to tell a friend about it. And subscribe, so you’ll never miss an episode. We’d love to hear from you. Follow us on BlueSky (@thetopicistrek), visit our Facebook page or call us at 816-TREKKER, that’s (816) 873-5537 Don’t put on the red shirt! END RECORDING – HAILING FREQUENCIES CLOSED

In this episode, Scott Becker breaks down 5 key worries including market declines, billionaire losses, retirement risks, rising national debt, and concerns about Apple's outlook.

In this episode, Scott Becker breaks down 5 key worries including market declines, billionaire losses, retirement risks, rising national debt, and concerns about Apple's outlook.

New book alert! We are back to Skyclan for Skyclan's Destiny! We look at covers, survive a prologue, and meet way to many cats.Resources:Mobilize.usStand With MinnesotaBook: Super Edition: Skyclan's DestinySupport us on Ko-fi! WCWITCast Ko-fiFollow us on BlueSky! WCWITCastFollow us on Instagram! WCWITCastCat Fact Sources:A lost cat's mysterious 2-month, 900-mile journey home to California - Houston HeraldCat lost in Yellowstone National Park reunites with owners in California | CNNMissing house cat makes incredible trek from Yellowstone to California - Los Angeles TimesMusic:Happy Boy End Theme Kevin MacLeod (incompetech.com)Licensed under Creative Commons: By Attribution 4.0https://creativecommons.org/licenses/by/4.0/This transformative podcast work constitutes a fair-use of any copyrighted material as provided for in section 107 of the US copyright law. Warrior Cats: What is That? is not endorsed or supported by Harper Collins and/or Working Partners. All views are our own.

A Reddit thread revealed the most depressing bachelor pads ever—guys showing off lounge rooms with fold-out camping chairs facing walls, a spin bike and a picture of a horse, and one bloke who doesn't even have a TV just sitting on his couch staring at nothing. We discovered you're apparently not supposed to put your couch against the wall (it has to be slightly forward to look nice, even if it makes your living area smaller), and Tim defended his halfway house era where he had fantastic furniture with a two-person wooden-armed couch you couldn't even lay on.See omnystudio.com/listener for privacy information.

Seth and Sean discuss who the most depressing team in the NFL to be a fan of is, why it's the Falcons, and react to CJ Gardner-Johnson on a livestream being petty about the Texans.

Seth and Sean discuss why the Falcons are the most depressing team in the NFL right now, react to CJ Gardner-Johnson getting petty about the Texans in a livestream, talk about how it's tough rooting for the USA team in the World Baseball Classic when you hate Aaron Judge and Bryce Harper, Texans fans keeping eyes open for a Will Anderson Jr. extension that could be coming this week, and see what the ITL question of the day is.

Do you remember The Grey from 2011? Of course you do. It's basically the cinematic equivalent of clinical depression… but with wolves. Join us as we follow Liam Neeson, Dermot Mulroney, and Frank Grillo after they literally fall out of the sky and begin one of the bleakest nature hikes ever filmed through the stunning Alaskan wilderness. Between the plane crash, the freezing cold, the elements, and some very angry local wildlife, the odds of a happy ending are… not great. But hey, we're going to hope anyway.

Are you sucked in the "Traumaverse"? Does recovery feel Heavy, Dark, and Depressing? Besties, this episode is for you! Today I help you tackle the emotional weight that can come with the healing journey and trauma recovery. We'll share practical tips to help you bring balance and joy back into your life, emphasizing the importance of integrating playful, lighthearted activities. ______________________________________MENTIONED IN PODCAST:

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3857: Fritz Gilbert sheds light on the emotional challenges many face after leaving the workforce, revealing that retirement can increase the risk of depression, especially for those whose identity is closely tied to their careers. Drawing from research and personal reflection, he outlines how cultivating hobbies, social connections, and a sense of purpose before retiring can significantly boost well-being in this new life chapter. Read along with the original article(s) here: https://www.theretirementmanifesto.com/will-retirement-be-depressing/ Quotes to ponder: "Be intentional in your retirement planning years, with a focus on incorporating non-financial elements into your plan." "The key to a happier retirement was having ‘multiple selves', which means hobbies and other activities to keep them busy." "Populate a bucket list of items you'd like to do in retirement. Broaden it to include categories beyond travel. Stretch yourself." Episode references: Ready To Retire? by Lyndsay Green: https://www.amazon.com/Ready-Retire-Spouse-Reality-Retirement/dp/1443440566 Institute of Economic Affairs – Work Longer, Live Healthier: https://iea.org.uk/publications/research/work-longer-live-healthier Learn more about your ad choices. Visit megaphone.fm/adchoices