Podcasts about biological processes

In this episode of the Cornelius Seed podcast, Juan and James Cornelius discuss the challenges of managing crop residue and introduce the concept of Residue Release. They explore its benefits, application techniques, and the biological processes involved in residue breakdown. The conversation emphasizes the flexibility of the product, its compatibility with other farming practices, and the potential for improved soil health and crop yields. 00:00 Introduction to Residue Release05:15 Application Timing and Benefits10:34 Biological Processes in Residue Breakdown14:21 Practical Application and Flexibility16:52 Solving Problems for Farmers20:05 Final Thoughts

In this episode, Dr. Robert Whitfield speaks with Dr. Brandy Cummings, a clinical nutritionist, about how important circadian rhythms are for our health and recovery. Dr. Whitfield opens up about personal struggles with sleep issues and stresses how crucial it is to have a strong foundation for recovery. Dr. Cummings dives into how light exposure affects our biological processes, recommending morning sunlight and grounding practices. They also discuss how to align eating habits with our circadian rhythms and how to handle artificial light exposure. Tune in to hear handy tips for boosting sleep quality and overall wellness. Plus, Dr. Cummings shares exciting news about her upcoming "Resilient Motherhood Summit (https://www.resilientmotherhoodsummit.com/a/2148047258/bF3bBeQT)," aimed at supporting mothers' health. Connect with Dr. Cummings www.resilientmotherhood.health (http://www.resilientmotherhood.health) Instagram (www.instagram.com/resilientmotherhood.health) Facebook (www.facebook.com/resilientmotherhood.health) TikTok (www.tiktok.com/@resilientmotherhood) Show Highlights: Focus on Sleep and Circadian Rhythm (00:01:33) Importance of sleep in recovery and optimizing circadian rhythms Importance of Light Exposure (00:02:38) How circadian rhythms and light exposure impact overall health and wellness Grounding and Electron Intake (00:12:34) Benefits of grounding and electron intake for cellular health and energy production Nutrition and Energy Balance (00:14:00) Significance of protein and healthy fats in maintaining energy levels Timing of Physical Activity (00:21:13) Importance of early morning walks to align with natural light and improve overall health Nervous System Support (00:24:37) Nervous system support alongside detox protocols for chronic illness patients Affordable Light Solutions (00:25:43) Tips on free or low-cost solutions for light management to enhance health Bio. Dr. Brandy Cummings Dr. Brandy Cummings, DCN, is not your typical nutritionist—she's a former blackjack dealer who routinely chooses steak over quinoa, roasted veggies over kale chips, and, most importantly, she understands. Her passion for root cause-focused nutrition stems from her own struggles with illness, infertility, and feeling forgotten by conventional medicine. After overcoming severe mold exposure that triggered the loss of her first pregnancy as well as countless other debilitating symptoms, Dr. B explored every corner of improving cellular health; she researched overlooked causes of chronic illness, such as mold, parasites, reactivated viral infections, and a dysregulated nervous system and was alarmed at the lack of continuous care offered by the conventional model. Dr. Cummings holds an impressive list of qualifications, with her Doctorate of Clinical Nutrition from the University of Western States in Portland, OR. She lives in Idaho with her husband and two young daughters and is a proud homeschooler, foodie, and Lego enthusiast. You can find her at www.resilientmotherhood.health. (http://www.resilientmotherhood.health) Links and Resources Let's Connect... Podcast: https://podcasts.apple.com/gb/podcast/breast-implant-illness/id1678143554 Spotify: https://open.spotify.com/show/1SPDripbluZKYsC0rwrBdb?si=23ea2cd9f6734667 TikTok: https://www.tiktok.com/@drrobertwhitfield?t=8oQyjO25X5i&r=1 IG: https://www.instagram.com/breastimplantillnessexpert/ FB: https://www.facebook.com/DrRobertWhitfield Linkedin: https://www.linkedin.com/in/dr-robert-whitfield-md-50775b10/ X: https://x.com/rob_whitfieldmd Read this article - https://www.breastcancer.org/treatment/surgery/breast-reconstruction/types/implant-reconstruction/illness/breast-implant-illness Shop: https://drrobssolutions.com SHARP: https://www.harp.health NVISN Labs - https://nvisnlabs.com/ Get access to Dr. Rob's Favorite Products below: Danger Coffee - Use our link for mold free coffee - https://dangercoffee.com/pages/mold-free-coffee?ref=ztvhyjg JASPR Air Purifier - Use code DRROB for the Jaspr Air Purifier - https://jaspr.co/ Echo Water - Get high quality water with our code DRROB10 - https://echowater.com/ BallancerPro - Use code DRROBVIP for the world's leader in lymphatic drainage technology - https://ballancerpro.com Ultrahuman - Use code WHITFIELD10 for the most accurate wearable - https://www.ultrahuman.com/ring/buy/us/?affiliateCode=drwhitfield

A Year in Review from previous episodes. 00:00 - Intro 00:42 - Warning Against Comparing Rates; why comparing autism rates across different time periods is misleading due to changes in diagnostic criteria and definitions.02:07 - Historical Context; the Bayh-Dole Act, DSM acceptance of Autism, and changes in vaccination schedules, affecting Autism definitions; Core Autism Characteristics04:30 - Educational Challenges; Describes the typical school day's structure as potentially overwhelming for Autistic individuals due to frequent subject changes.05:36 - Intense Focus; Autistic individuals might fixate on topics with abnormal intensity or focus, which is a hallmark of Autism.08:40 - The biology of Autism allows us to be comfortable within ourselves; contrasting with societal expectations.09:09 - Employment and Anxiety; Considers how the expectation to fit into social norms can lead to anxiety and challenges in employment for Autistic individuals.10:10 - ADHD and Autism; Challenges the notion of coexisting ADHD and Autism, 14:26 - Early Detection; UCLA study on very young children showing altered salience network connectivity, hinting at early signs of Autism.14:49 - Developmental Timing; emphasizes that Autism likely starts in the womb, suggesting prenatal development as a critical area for research.15:14 - Neurodevelopmental Perspective; Autism as underdeveloped or abnormally developed cells, linking it to broader neurodevelopmental disorders.16:03 - Comorbid Conditions: Explores the concept of Autism being associated with various other conditions due to shared developmental issues.16:47 - Biological Processes: cellular proliferation, differentiation, and migration in the womb, crucial for brain development.17:41 - Mitochondria and Autism18:30 - Oxytocin & Autism; oxytocin as a molecule of interest, particularly its pathways and their implications for social behavior in Autism.20:29 - Social Reward System; Explains how oxytocin and serotonin interaction in the brain contributes to the rewarding nature of social interaction, which might be lacking in Autism.21:21 - Serotonin Synthesis; Details the synthesis of serotonin in both the GI tract and the brain, mentioning the enzymes involved and their significance.22:34 - Tryptophan and Light; Discusses how light affects tryptophan, an amino acid precursor to serotonin, and its role in biological processes.23:33 - Supplementing Relationships; Explores how visual thinking and movies can serve as a form of interaction for Autistic individuals, offering comfort or learning.25:17 - Visual Learning; Highlights the concept of "thinking in pictures" and how it leads to accelerated learning or Autistic intelligence.27:47 - Autistic Comfort and Societal Expectations; Advises against forcing Autistic individuals into societal norms that don't align with their natural inclinations, emphasizing understanding and acceptanceX; https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

In this episode of Vibe Science, co-hosts Ryan Alford and Chris Hansen explore the science of circadian rhythms with guest Andreas Christou, a movement specialist and lifestyle coach. Andreas dives into how these internal clocks regulate various body systems, highlighting the profound effects of natural versus artificial light on our health. He emphasizes the power of sunlight exposure, grounding practices, and quality sleep as essentials for maintaining overall well-being. The conversation also includes practical strategies for reducing blue light exposure and aligning daily routines with natural light cycles to boost both physical and mental health.TAKEAWAYSImportance of circadian rhythms for physical and mental healthBiological clocks and their regulation of bodily systemsEffects of natural light exposure on health and well-beingDetrimental impact of artificial light, particularly blue light, on melatonin productionStrategies for aligning daily routines with natural light cyclesBenefits of grounding and connecting with the earth for energy and healthRole of mitochondria in energy production and overall vitalityInfluence of the nervous system on energy levels and relaxationImportance of supplements and minerals for supporting mitochondrial functionPractical tips for optimizing health through light exposure and lifestyle adjustments Follow us on Instagram: @Vibe.Science Subscribe to our YouTube Page: www.youtube.com/@Vibe.Science

In the journal, Nature, researchers published a study discussing mental health. This study suggests a connection between one area of the brain, and the size of that area, to a person's risk for experiencing depression. Doctor Peter Lin, CBC's medical columnist, joined us on the line to give more details.

In this episode, we explored a range of topics from the biological processes of aging to cutting-edge techniques for maintaining vitality. Our goal was to provide you with actionable insights and tips to help you enhance your well-being. Here's a recap of the topics we discussed: • Biological Processes of Aging: Understanding cellular senescence, DNA damage, and oxidative stress. • Nutrition for Longevity: Anti-aging superfoods, the role of antioxidants, and benefits of caloric restriction and intermittent fasting. • Importance of Physical Activity: Types of exercises for longevity, strength training, and cardiovascular health. • Sleep and Recovery: The role of quality sleep, tips for improving sleep hygiene, and the impact of poor sleep on aging. • Stress Management and Mental Health: Effects of chronic stress, stress management techniques, and the connection between mental health and longevity. • Hormonal Balance and Aging: Hormonal changes in men and women, strategies for maintaining hormonal balance, and hormone replacement therapy. • Gut Health and Its Role in Aging: The importance of a healthy gut microbiome, supporting gut health, and the gut-brain connection. • Innovative Anti-Aging Treatments: Overview of NAD+ therapy, stem cell therapy, and other emerging treatments. • Functional Lab Testing for Longevity: Key biomarkers, interpreting results, and the role of genetic testing. • Lifestyle Modifications for a Longer Life: Impact of lifestyle choices, practical tips for daily habits, and the importance of sustainable changes. Remember, while we can't control how long we live, we can certainly take steps to ensure that our years are filled with health and vitality. Optimization is key, and with the right knowledge and tools, we can live our best lives every day. Stay connected with us for more insights on optimizing your health and achieving timeless well-being. Thank you for being part of our community, and we look forward to bringing you more valuable content soon! Connect with Nikki: Website: www.tastelifenutrition.com Facebook: @TasteLifeNutrition Instagram: @tastelifenutrition Apple Podcasts: apple.co/3V8Q6wT Spotify: spoti.fi/3SZYQDw Sponsor: www.cellcore.com

Im heutigen Podcast werde ich einige unterhaltsame aber auch ernsthafte Geschichten erzählen, zu einem Thema, das ich in verschiedenen anderen Episoden schon angesprochen habe: »Unintended Consequences — Unerwartete Folgen« In dieser Episode wird es also weniger um eine tiefe Analyse der Gründe für unerwartete Folgen bestimmter Maßnahmen gehen, sondern es soll vielmehr die Breite und Tragweite der Problematik anschaulich gemacht werden. Dies trifft sowohl auf die Fälle zu, wo die unerwünschten Folgen negativer als auch positiver Natur sind. In der Episode spreche ich Beispiele aus der Chemie, der Ökologie, Politik und Wissenschaft an. Es ist auch das erste Mal, dass mit Barbara Streisand eine Schauspielerin und Sängerin thematisiert wird, oder besser gesagt, ihre Villa am Strand! Welche Rolle spielen simple und komplexe Systeme, oder Probleme mit engem oder weitem Kontext? Was können wir tun, um schwerwiegende unerwünschte Folgen zu vermeiden und positive zu begünstigen? “All history is the history of unintended consequences.”, T. J. Jackson Lears Referenzen Andere Episoden Episode 86: Climate Uncertainty and Risk, a conversation with Dr. Judith Curry Episode 80: Wissen, Expertise und Prognose, eine Reflexion Episode 76: Existentielle Risiken Episode 72: Scheitern an komplexen Problemen? Wissenschaft, Sprache und Gesellschaft — Ein Gespräch mit Jan David Zimmermann Episode 69: Complexity in Software Episode 37: Probleme und Lösungen Episode 27: Wicked Problems Episode 25: Entscheiden unter Unsicherheit Episode 23: Frozen Accidents Episode 10: Komplizierte Komplexität Fachliche Referenzen Rory Sutherland, Alchemy, Virgin Digital (2019) Los Angeles Times, Unintended consequences of conserving water: leaky pipes, less revenue, bad odors (2015) Rachel Carson, Silent Spring, Penguin Classic (1962) Bloomberg, Tree Planting Program in Mexico may Encourage Deforestation (2021) Tokunaga, E., Yamamoto, T., Ito, E. et al. Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers. Sci Rep 8, 17131 Barbara Streisand Estate (Photo): Copyright (C) 2002 Kenneth & Gabrielle Adelman, California Coastal Records Project Thomas Sowell, Intellectuals and Society, Basic Books (2012) Vaclav Smil, Invention and Innovation: A Brief History of Hype and Failure, MIT Press (2023) Reason TV, Great Moments in Unintended Consequences (YouTube Playlist) Niall Ferguson on Regulation (YouTube), Zitat T. J. Jackson Lears

The ‘scientific' consensus is that the Earth is some billions of years old (on the order of four-and-a-half billion years old) and that the Universe is some fourteen or so billion years old. But Scripture paints a different picture. Which may, should, or must the Christian believe? Is the contention of the so-called ‘scientific community' even reasonable? Which is to say: Does it stand up to scrutiny? Knowledge is warranted true belief, and so it is vitally important to ask upon what warrant the scientists base their beliefs. As we will show in this episode, the Christian position is — unequivocally — that the Earth is ancient in terms of created age and young (some six thousand or so years) in terms of chronological age and that God created all things in six literal, twenty-four-hour days. As to the supposedly ‘scientific' position? Well, it does not stand up particularly well under scrutiny. Subscribe to the podcast here. Show Notes Hexameron [Wikipedia] See Also “Geochronologically Speaking” “James Tour: The Origin of Life Has Not Been Explained” [YouTube] “James Tour & Stephen Meyer Bring Clarity to the Origin of Life Debate (Ep. 1)” [YouTube] Discover Science [YouTube Channel] “Copying and Pasting Passwords” (Relevant for the math involved in the latter part of the episode.) Creation.com CreationWiki.com Further Reading Cosmic background radiation [Wikipedia] DNA [Wikipedia] RNA [Wikipedia] mRNA [Wikipedia] Chirality [Wikipedia] “The Significance of Chirality in Drug Design and Development” “Nature's mirror: The code for chirality” “Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers” Amino Acid [Wikipedia] Abiogenesis [Wikipedia] Neo-Darwinism [Wikipedia] Modern Synthesis [Wikipedia] Hard Problem of Consciousness [Wikipedia] Qualia [Wikipedia] Probability [Wikipedia] Blood Clotting “How it all starts: initiation of the clotting cascade” “Coagulation Cascade” Coagulation [Wikipedia] Vision Visual Phototransduction [Wikipedia] “Phototransduction” Labeling of Fertilizer [Wikipedia] Deoxyribose [Wikipedia] Organophosphate [Wikipedia] Books Darwin's Black Box: The Biochemical Challenge to Evolution by Michael Behe Theistic Evolution: A Scientific, Philosophical, and Theological Critique edited by J. P. Moreland, et al. Also available on ChristinBook.com. Parental Warnings None.

If bright light at night bothers you, it is much worse for marine life, and they don't realize it, they just react. Their instinctual biological processes change in reaction to artificial light and sky glow which then affects the food chain. To add to that, the blue light from LED's penetrates deeper into the water. The sky glow disrupts biological processes that are guided by moonlight. Dr. Davies and Prof. Smyth are doing the research. Now it's up to us to take action. Dr Davies is a marine conservation ecologist at the University of Plymouth, UK working. His research seeks to understand the impacts and management of man-made global change on ecosystems, and human-environment interrelationships. He has published research on the impacts and management of a variety of global change issues - most notably Artificial Light at Night (ALAN). Prof. Tim Smyth is the Head of Science for Marine Biogeochemistry and Observations at PML. This involves leading a team of around 20 people ranging from PhD students to experienced senior scientists across a range of disciplines from air-sea exchange, nutrient cycling to molecular science within the broad remit of marine biogeochemistry. His brief also includes oversight of the Atlantic Meridional Transect (AMT) as well as the Western Channel Observatory (WCO) which he has been leading for the past 15 years. 

Con + tempor + ary - “with” + “tempor, temporis” “With the times” (Contemporaneous) Tempo - the speed at which a passage of music is or should be played. (Tempor) Co + habitation = (habito, habitare - “to live/ to live and/or have a home”) Co + labor + ate = to work together Con + solidate = to bring together with (solidatum= to make solid/ bring together) Con + done = give with/together “With” + “gift” Solidarity = support or sympathy “Solidatum” - to make solid/ bring together _______________________________________________________________________ BIO Processes Telomere - a compound structure at the end of a chromosome. “telos(end)” + “part” Telophase - the final phase of cell division, between anaphase and interphase, in which the chromatids or chromosomes move to opposite ends of the cell and two nuclei are formed. “End” + “stage” Mitosis - a type of cell division that results in two daughter cells each having the same number and kind of chromosomes as the parent nucleus, typical of ordinary tissue growth. “mitos(thread)” Mitochondria - POWERHOUSE OF THE CELL “Thread” + “kondros(granule)” + “likeness/related to” Chondromalcia patellae (genitive form of Patella) - degeneration of cartilage in the knee, usually caused by excessive wear between the patella and lower end of the femur. “Granule(transitions into - cartilage)” + “soft/softening” Chondrosarcoma - a type of bone cancer that develops in cartilage cells. Cartilage is the specialized, gristly connective tissue that is present in adults and the tissue from which most bones develop. Cartilage plays an important role in the growth process. “Cartilage” + “ flesh/muscle” + “tumor” ______________________________________________________________________________________________ Legal Nomenclature Jurisprudence - study, theory, or philosophy of law “Juris (from “ius, iuris” = law) + “prudentia(knowledge)” In fact; philosophy = philo(love/lover of) + sophos(wise) And further!!! Sophomore = sophos(wise) + moros(stupid/fool) Jurisdiction - the power, right, or authority to interpret and apply the law a matter that falls within the court's jurisdiction “Law” + “dictio(participle form of “to say” aka ‘saying')” Perjure - willfully tell an untruth when giving evidence to a court; commit perjury. “per(wrong)” + “ius(law)” - to wrong the law Impunity - freedom from punishment “in(not)” + “punire/punitum(to punish)” Subpoena - a writ ordering a person to attend a court. “under/beneath” + “penalty” (of law) Litigation - The process of a lawsuit “litigare/litigatum(to press a lawsuit)” --- Support this podcast: https://anchor.fm/liam-connerly/support

Dr. Clarice D. Aiello (https://samueli.ucla.edu/people/clarice-aiello/), is Assistant Professor, Electrical and Computer Engineering, at the UCLA Samueli School Of Engineering. Dr. Aiello is also leader of the new Quantum Biology Tech (QuBiT) Lab, a new center dedicated to interdisciplinary research on the possible quantum underpinnings of biological processes, within the UCLA California NanoSystems Institute (https://cnsi.ucla.edu/). With her Ph.D. from MIT in electrical engineering, and postdoctoral appointments in bio-engineering at Stanford, and in chemistry at Berkeley, Dr. Aiello's research group, the Quantum Biology Tech (QuBiT) Lab, is focused on performing quantum measurements on “living sensors,” such as proteins, cells and microorganisms, to understand how they interact with their environment. This knowledge can lead to a broad range of discoveries, for example, how animals navigate, advanced therapeutics for metabolic-related diseases, and quantum information strategies for computing.

Huberman Lab Podcast Notes Key Takeaways Attention deficit disorder (ADD) is now called Attention deficit hyperactivity disorder (ADHD) when it became clear there was a hyperactive componentDespite the stereotype, people with ADHD can be hyper-focused but only focus attention on things of interestDopamine is the neurotransmitter that underlies enjoyment and curiosity – most ADHD pharmaceuticals are stimulants with a play on the dopamine systemThere's a fine line between street drugs and therapeutics for ADHD: Ritalin is closely related to speed; Adderall closely resembles methamphetamineNon-pharmaceutical and behavioral treatments for ADHD may be used in combination with pharmaceuticals with the potential to wean off as possibleWhile research for elimination diets has been controversial as a treatment for ADHD, it seems like avoiding simple sugars and exploring allergies to make informed food choices is worthwhileNewer studies point to the idea that smartphone use is inducing ADHD in adolescence if used more than 60 minutes per day, and approximately 120 minutes per day in adultsRead the full notes @ podcastnotes.orgIn this episode, I discuss ADHD (Attention-Deficit Hyperactivity Disorder): what it is, the common myths, and the biology and psychology of ADHD. I discuss both behavioral and pharmacologic treatments for ADHD, and brain-machine interface tools. I also discuss behavioral training protocols that can improve focus in people with ADHD and those without ADHD, and for people of different ages. I discuss the role of dopamine in coordinating 'default-mode' and 'task-related' neural networks, attentional "blinks" (lapses of attention) and how to overcome them, and the role of actual blinks in time perception and attention. Finally, I review some of the prescription and over-the-counter compounds for increasing focus such as Adderall, Ritalin, Modafinil and Armodafinil, the racetams, Alpha-GPC and phosphatidylserine and the role of diet for managing ADHD (and the controversies of diet for ADHD). The role of cell phones/technology in ADHD and ADHD-like challenges with focus are also discussed. Throughout, both basic science and clinical scenarios, as well as applicable tools and resources are covered. Thank you to our sponsors: Roka - https://www.roka.com -- code "huberman" Belcampo - https://www.belcampo.com/huberman Helix Sleep - https://www.helixsleep.com/huberman   Our Patreon page: https://www.patreon.com/andrewhuberman   Supplements from Thorne: http://www.thorne.com/u/huberman   Support Research in the Huberman Lab at Stanford: https://hubermanlab.stanford.edu/giving   Social: Instagram - https://www.instagram.com/hubermanlab Twitter - https://twitter.com/hubermanlab Facebook - https://www.facebook.com/hubermanlab Website - https://hubermanlab.com Email Newsletter - https://hubermanlab.com/neural-network   Links: Review of Compounds for ADHD, Smart Drugs & Focus - https://www.fbscience.com/Landmark/articles/10.52586/4948 Review of Atypical Compounds for ADHD - https://www.hindawi.com/journals/np/2016/1320423/ Study of Focus Protocol In ADHD & Non-ADHD Children - https://www.mdpi.com/1660-4601/17/13/4780   Timestamps: 00:00:00 Introduction & Note About Diagnosis 00:03:27 Sponsors  00:07:56 ADHD vs. ADD: Genetics, IQ, Rates in Kids & Adults 00:13:00 Attention & Focus, Impulse Control 00:14:57 Hyper-focus  00:16:45 Time Perception 00:18:25 The Pile System 00:20:00 Working Memory 00:24:10 Hyper-Focus & Dopamine  00:26:40 Neural Circuits In ADHD: Default Mode Network & Task-Related Networks  00:32:57 Low Dopamine in ADHD & Stimulant Use & Abuse 00:37:10 Sugar, Ritalin, Adderall, Modafinil & Armodafinil  00:47:00 Non-Prescribed Adderall, Caffeine, Nicotine 00:49:18 How Stimulants “Teach” the Brains of ADHD Children to Focus 00:52:00 When To Medicate: A Highly Informed (Anecdotal) Case Study 00:56:35 Elimination Diets & Allergies In ADHD 01:04:46 Omega-3 Fatty Acids: EPAs & DHAs  01:07:00 Modulation vs Mediation of Biological Processes 01:10:50 Attentional Blinks  01:16:56 Open Monitoring & 17minute Focus Enhancement  01:22:50 Blinking, Dopamine & Time Perception; & Focus Training  01:30:10 Reverberatory Neural & Physical Activity 01:33:40 Adderall, Ritalin & Blink Frequency 01:35:00 Cannabis  01:37:30 Interoceptive Awareness  01:41:15 Ritalin, Adderall, Modafinil, Armodafinil; Smart Drugs & Caffeine: Dangers 01:48:05 DHA Fatty Acids, Phosphatidylserine 0:1:50:54 Ginko Biloba  01:51:45 Modafinil & Armodafanil: Dopamine Action & Orexin 01:56:19 Acetylcholine: Circuits Underlying Focus; Alpha-GPC 01:59:04 L-Tyrosine, (PEA) Phenylethylamine  02:01:23 Racetams, Noopept  02:05:15 Transcranial Magnetic Stimulation; Combining Technology & Pharmacology  02:09:14 Smart Phones & ADHD & Sub-Clinical Focus Issues In Adults & Kids 02:14:30 Synthesis/Summary 02:16:10 Support for Podcast & Research, Supplement Resources   Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.   Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com 

In this episode, I discuss ADHD (Attention-Deficit Hyperactivity Disorder): what it is, the common myths, and the biology and psychology of ADHD. I discuss both behavioral and pharmacologic treatments for ADHD, and brain-machine interface tools. I also discuss behavioral training protocols that can improve focus in people with ADHD and those without ADHD, and for people of different ages. I discuss the role of dopamine in coordinating 'default-mode' and 'task-related' neural networks, attentional "blinks" (lapses of attention) and how to overcome them, and the role of actual blinks in time perception and attention. Finally, I review some of the prescription and over-the-counter compounds for increasing focus such as Adderall, Ritalin, Modafinil and Armodafinil, the racetams, Alpha-GPC and phosphatidylserine and the role of diet for managing ADHD (and the controversies of diet for ADHD). The role of cell phones/technology in ADHD and ADHD-like challenges with focus are also discussed. Throughout, both basic science and clinical scenarios, as well as applicable tools and resources are covered. Thank you to our sponsors: Roka - https://www.roka.com -- code "huberman" Belcampo - https://www.belcampo.com/huberman Helix Sleep - https://www.helixsleep.com/huberman   Our Patreon page: https://www.patreon.com/andrewhuberman   Supplements from Thorne: http://www.thorne.com/u/huberman   Support Research in the Huberman Lab at Stanford: https://hubermanlab.stanford.edu/giving   Social: Instagram - https://www.instagram.com/hubermanlab Twitter - https://twitter.com/hubermanlab Facebook - https://www.facebook.com/hubermanlab Website - https://hubermanlab.com Email Newsletter - https://hubermanlab.com/neural-network   Links: Review of Compounds for ADHD, Smart Drugs & Focus - https://www.fbscience.com/Landmark/articles/10.52586/4948 Review of Atypical Compounds for ADHD - https://www.hindawi.com/journals/np/2016/1320423/ Study of Focus Protocol In ADHD & Non-ADHD Children - https://www.mdpi.com/1660-4601/17/13/4780   Timestamps: 00:00:00 Introduction & Note About Diagnosis 00:03:27 Sponsors  00:07:56 ADHD vs. ADD: Genetics, IQ, Rates in Kids & Adults 00:13:00 Attention & Focus, Impulse Control 00:14:57 Hyper-focus  00:16:45 Time Perception 00:18:25 The Pile System 00:20:00 Working Memory 00:24:10 Hyper-Focus & Dopamine  00:26:40 Neural Circuits In ADHD: Default Mode Network & Task-Related Networks  00:32:57 Low Dopamine in ADHD & Stimulant Use & Abuse 00:37:10 Sugar, Ritalin, Adderall, Modafinil & Armodafinil  00:47:00 Non-Prescribed Adderall, Caffeine, Nicotine 00:49:18 How Stimulants “Teach” the Brains of ADHD Children to Focus 00:52:00 When To Medicate: A Highly Informed (Anecdotal) Case Study 00:56:35 Elimination Diets & Allergies In ADHD 01:04:46 Omega-3 Fatty Acids: EPAs & DHAs  01:07:00 Modulation vs Mediation of Biological Processes 01:10:50 Attentional Blinks  01:16:56 Open Monitoring & 17minute Focus Enhancement  01:22:50 Blinking, Dopamine & Time Perception; & Focus Training  01:30:10 Reverberatory Neural & Physical Activity 01:33:40 Adderall, Ritalin & Blink Frequency 01:35:00 Cannabis  01:37:30 Interoceptive Awareness  01:41:15 Ritalin, Adderall, Modafinil, Armodafinil; Smart Drugs & Caffeine: Dangers 01:48:05 DHA Fatty Acids, Phosphatidylserine 0:1:50:54 Ginko Biloba  01:51:45 Modafinil & Armodafanil: Dopamine Action & Orexin 01:56:19 Acetylcholine: Circuits Underlying Focus; Alpha-GPC 01:59:04 L-Tyrosine, (PEA) Phenylethylamine  02:01:23 Racetams, Noopept  02:05:15 Transcranial Magnetic Stimulation; Combining Technology & Pharmacology  02:09:14 Smart Phones & ADHD & Sub-Clinical Focus Issues In Adults & Kids 02:14:30 Synthesis/Summary 02:16:10 Support for Podcast & Research, Supplement Resources   Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.   Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com 

Today on Mushroom Hour we have the privilege of speaking with Jeff Lowenfels. Jeff is the author of the Award-winning books “Teaming With Microbes: The Organic Gardener’s Guide To The Soil Food Web”, “Teaming With Nutrients: The Organic Gardener’s Guide to Optimizing Plant Nutrition” and “Teaming With Fungi: The Organic Grower’s Guide to Mycorrhizae”. Jeff Lowenfels has become a leader in the organic gardening/sustainability movement because of these best-selling books. His “Guide to the soil food web” has been hailed as one of the most important gardening books in the last 25 years. His talks have converted tens of thousands of gardeners at venues throughout North and South America to follow the path of organic gardening. Jeff hosted Alaska public television’s most popular show, “Alaska Gardens with Jeff Lowenfels.” Most importantly for him, Jeff is the founder of the national program “Plant A Row for The Hungry.” This program is active all 50 states and Canada and has resulted in millions pounds of garden produce being donated to feed the hungry every year.    TOPICS COVERED:   Transformation from “Chemical Head” to Organic Gardener   Discovering the Soil Food Web   Teaming with Microbes  Nematodes, Protozoa, Fungi and the Rhizosphere   Testing for Soil Health   Teaming with Nutrients   How do Plants Eat?   Biological Processes of Plant Cells   Roles of Mycorrhizal Fungi   Humans Controlled by Microorganisms   Spiritual Microbial Ecology   Chemical Agriculture & the Soil Food Web   Our Future Depends on Soil   Planting a Row for the Hungry   EPISODE RESOURCES:   Jeff Lowenfels' Column: https://www.adn.com/author/jeff-lowenfels/   "Teaming with Microbes": https://www.amazon.com/Teaming-Microbes-Organic-Gardeners-Revised/dp/1604691131   "Teaming with Nutrients": https://www.amazon.com/Teaming-Nutrients-Gardeners-Optimizing-Nutrition/dp/1604693142/   "Teaming with Fungi": https://www.amazon.com/Teaming-Fungi-Organic-Mycorrhizae-Gardeners/dp/1604697296/   Rudolf Steiner: https://en.wikipedia.org/wiki/Rudolf_Steiner   Dr. Elaine Ingham: https://www.soilfoodweb.com/   Microbiometer (Test your soil biomass!): https://microbiometer.com/   Plant a Row for the Hungry: https://gardencomm.org/PAR   

Nuclear factor interleukin 3 (NFIL3, also known as E4-binding protein 4, E4BP4) is a repressor of numerous genes. NFIL3 contains a basic leucine zipper domain, comprising amino acids 73–146, among 462 residues; the N-terminal part of this domain directly binds to DNA, while the C-terminal region is responsible for homo- or heterodimerization of the protein. Amino acids 299–363 comprise a transcriptional repression domain where the N-terminal part of this domain directly binds to DNA, while the C-terminal region is responsible for homo- or heterodimerization of the protein and amino acids 299–363 comprise a transcriptional repression domain. Please SUBSCRIBE and help out with $ donations! --- Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.29.318931v1?rss=1 Authors: Nadeau, R., Shahryari Fard, S., Scheer, A., Hashimoto-Roth, E., Nygard, D., Abramchuk, I., Chung, Y.-E., Bennett, S. A. L., Lavallee-Adam, M. Abstract: While the COVID-19 pandemic is causing important loss of life, knowledge of the effects of the causative SARS-CoV-2 virus on human cells is currently limited. Investigating protein-protein interactions (PPIs) between viral and host proteins can provide a better understanding of the mechanisms exploited by the virus and enable the identification of potential drug targets. We therefore performed an in-depth computational analysis of the interactome of SARS-CoV-2 and human proteins in infected HEK293 cells published by Gordon et al. to reveal processes that are potentially affected by the virus and putative protein binding sites. Specifically, we performed a set of network-based functional and sequence motif enrichment analyses on SARS-CoV-2-interacting human proteins and on a PPI network generated by supplementing viral-host PPIs with known interactions. Using a novel implementation of our GoNet algorithm, we identified 329 Gene Ontology terms for which the SARS-CoV-2-interacting human proteins are significantly clustered in the network. Furthermore, we present a novel protein sequence motif discovery approach, LESMoN-Pro, that identified 9 amino acid motifs for which the associated proteins are clustered in the network. Together, these results provide insights into the processes and sequence motifs that are putatively implicated in SARS-CoV-2 infection and could lead to potential therapeutic targets. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.24.220335v1?rss=1 Authors: Sayed, M., Park, J. W. Abstract: MicroRNAs are small non-coding RNAs that are known for their role in post-transcriptional regulation of target genes. Typically, their functions are predicted by first identifying their target genes and then finding biological processes enriched in these targets. Current tools for miRNA functional analysis use only genes with physical binding sites as their targets and exclude other genes that are indirectly targeted transcriptionally through transcription factors. Here, we introduce a method to predict gene ontology (GO) annotations indirectly targeted by microRNAs. The proposed method resulted in better performance in predicting known miRNA-GO term associations compared to the canonical approach. To facilitate miRNA GO enrichment analysis, we developed an R Shiny application, miRinGO, that is freely available from GitHub at https://github.com/Fadeel/miRinGO Copy rights belong to original authors. Visit the link for more info

What if the person you cared most about suddenly became replaced by an identical duplicate? We explore the history and causes of this devastating delusion. References: Abumrad, J., & Krulwich, R. (2010, March 30). Seeing Impostors: When loved ones suddenly aren't. Retrieved November 29, 2019, from https://www.npr.org/templates/story/story.php?storyId=124745692 Bier, D. (2018, October 8). Capgras and dementia: The imposter syndrome. Retrieved November 29, 2019, from https://psychcentral.com/lib/capgras-and-dementia-the-imposter-syndrome/ Capgras delusion. (n.d.). Retrieved November 29, 2019, from https://en.wikipedia.org/wiki/Capgras_delusion Capgras delusion [Blog post]. (2018, November 7). Retrieved from Neuroscientifically challenged website: https://www.neuroscientificallychallenged.com/blog/capgras-delusion Darby, R. R., & Caplan, D. (2016). “Cat-gras” delusion: a unique misidentification syndrome and a novel explanation. Neurocase (Psychology Press), 22(2), 251–256. https://doi-org.ezproxy.bellevue.edu/10.1080/13554794.2015.1136335 Edelstyn, N. (2017, June 8). Ever thought a loved one was an imposter? That's the Capgras delusion. Retrieved November 29, 2019, from https://theconversation.com/ever-thought-a-loved-one-was-an-imposter-thats-the-capgras-delusion78291 Ogden, J. (2012, August 21). The Capgras Delusion: You are not my wife! [Blog post]. Retrieved from https://www.psychologytoday.com/us/blog/ trouble-in-mind/201208/the-capgras-delusion-you-are-not-my-wife The syndrome of Capgras. (2008). Psychiatry: Interpersonal & Biological Processes, 71(4), 371–378. Retrieved from https://search-ebscohost-com.ezproxy.bellevue.edu/login.aspx?direct=true&db=ccm&AN=105631705&site=eds-live

In this seminar we explore why human interventions such as euthanasia or use of biotechnologies are controversial. Is it wrong to intervene in biological processes? Human intervention in the living world gives rise to controversies where scientists are criticised for working on biotechnologies and physicians for ending life when a terminally ill patient is experiencing unmanageable suffering. This lecture will explain the perpetuation of political controversies by showing that scientific and moral assessments of human intervention in the living world are unsolvable because they are based on cognitive biases. Looking at case studies of such controversial issues (end of life intervention, GMOs and synthetic biology debates), my analysis will focus on the apparent clarity of the double contrast between natural beings and artificial objects on the one hand, and risk and realms of uncertainty on the other. The interesting point here is that the relationship between scientific expertise and political issues is clearly related to these implicit epistemological prerequisites.

Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data. Professor Jens Rittscher has a joint appointment between the Ludwig Institute for Cancer Research, the Target Discovery Institute and the Department of Engineering Science. His research aims to enhance our understanding of complex biological processes through the analysis of image data acquired at the microscopic scale.

Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data. Professor Jens Rittscher has a joint appointment between the Ludwig Institute for Cancer Research, the Target Discovery Institute and the Department of Engineering Science. His research aims to enhance our understanding of complex biological processes through the analysis of image data acquired at the microscopic scale.

Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data. Professor Jens Rittscher has a joint appointment between the Ludwig Institute for Cancer Research, the Target Discovery Institute and the Department of Engineering Science. His research aims to enhance our understanding of complex biological processes through the analysis of image data acquired at the microscopic scale.

According to NASA, the Curiosity rover has taken significant steps toward understanding how Mars may have lost much of its original atmosphere. Learning what happened to the Martian atmosphere will help scientists assess whether the planet ever was habitable. An important indicator is whether there is any methane present in the atmosphere. Scientists want to know about methane in the Martian atmosphere because life as we know it produces methane and most methane in Earth's atmosphere is due to biological processes. Today's first set of results came back negative for methane, meaning at present there appears to be no modern-day life. However these are preliminary results and NASA says that the hunt has just begun in earnest and not to draw any final conclusions yet.

Hear about natures natural nitrogen fixers.

Why nitrogen is important to plants and the communities of microorganisms living in the soil.

Diabetic nephropathy (DN) is a complex and chronic metabolic disease that evolves into a progressive fibrosing renal disorder. Effective transcriptomic profiling of slowly evolving disease processes such as DN can be problematic. The changes that occur are often subtle and can escape detection by conventional oligonucleotide DNA array analyses. We examined microdissected human renal tissue with or without DN using Affymetrix oligonucleotide microarrays (HG-U133A) by standard Robust Multi-array Analysis (RMA). Subsequent gene ontology analysis by Database for Annotation, Visualization and Integrated Discovery (DAVID) showed limited detection of biological processes previously identified as central mechanisms in the development of DN (e.g. inflammation and angiogenesis). This apparent lack of sensitivity may be associated with the gene-oriented averaging of oligonucleotide probe signals, as this includes signals from cross-hybridizing probes and gene annotation that is based on out of date genomic data. We then examined the same CEL file data using a different methodology to determine how well it could correlate transcriptomic data with observed biology. ChipInspector (CI) is based on single probe analysis and de novo gene annotation that bypasses probe set definitions. Both methods, RMA and CI, used at default settings yielded comparable numbers of differentially regulated genes. However, when verified by RT-PCR, the single probe based analysis demonstrated reduced background noise with enhanced sensitivity and fewer false positives. Using a single probe based analysis approach with de novo gene annotation allowed an improved representation of the biological processes linked to the development and progression of DN. The improved analysis was exemplified by the detection of Wnt signaling pathway activation in DN, a process not previously reported to be involved in this disease.