Podcasts about rabinovici

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Best podcasts about rabinovici

Latest podcast episodes about rabinovici

Dementia Matters
Talking about Tau: The Role of Tau PET Scans in Alzheimer's Research and Care

Dementia Matters

Play Episode Listen Later Apr 8, 2025 55:33


Early detection is a top priority in the field of Alzheimer's research, and one indicator of Alzheimer's disease is the buildup of tau in the brain. What is tau, though? How can we detect this protein, and what can it tell us about a person's symptoms or disease progression? Dr. Gil Rabinovici, a leader in the field of brain imaging, joins Dementia Matters this week for an in-depth discussion on the role of tau PET scans in Alzheimer's disease detection, research and clinical care. Guest: Gil Rabinovici, MD, professor, Department of Neurology, University of California San Francisco (UCSF), director, UCSF Alzheimer's Disease Research Center, study chair, Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) and New IDEAS studies, co-principal investigator, Alzheimer's Network for Treatment and Diagnostics (ALZ-NET), Longitudinal Evaluation of Alzheimer's Disease Study (LEADS) Show Notes Are you a clinician interested in receiving continuing education (CE) credits for listening to this episode? Find credit designation information, disclosures and evaluation information on our website and on the UW–Madison Interprofessional Continuing Education Partnership (ICEP) website. The accreditation for this course expires 4/7/2026. After this date, you will no longer be able to access the course or claim credit. Read “Criteria for Diagnosis and Staging of Alzheimer's Disease,” mentioned by Dr. Rabinovici at 18:43, on the Alzheimer's Association's website. Listen to our past episode with Dr. David Wolk, “LATE, Explained,” mentioned by Dr. Rabinovici at 26:31 on Spotify, Apple Podcasts and on our website. Connect with us Find transcripts and more at our website. Email Dementia Matters: dementiamatters@medicine.wisc.edu Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer's Disease Research Center's e-newsletter. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer's. All donations go toward outreach and production.

PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast
Gil Rabinovici, MD - At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies

PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast

Play Episode Listen Later Oct 22, 2024 48:08


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/GBW865. CME/MOC/NCPD/AAPA credit will be available until October 7, 2025.At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast
Gil Rabinovici, MD - At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast

Play Episode Listen Later Oct 22, 2024 48:08


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/GBW865. CME/MOC/NCPD/AAPA credit will be available until October 7, 2025.At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

PeerView Neuroscience & Psychiatry CME/CNE/CPE Audio Podcast
Gil Rabinovici, MD - At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies

PeerView Neuroscience & Psychiatry CME/CNE/CPE Audio Podcast

Play Episode Listen Later Oct 22, 2024 48:08


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/GBW865. CME/MOC/NCPD/AAPA credit will be available until October 7, 2025.At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

PeerView Neuroscience & Psychiatry CME/CNE/CPE Video Podcast
Gil Rabinovici, MD - At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies

PeerView Neuroscience & Psychiatry CME/CNE/CPE Video Podcast

Play Episode Listen Later Oct 22, 2024 48:08


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/GBW865. CME/MOC/NCPD/AAPA credit will be available until October 7, 2025.At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

PeerView Family Medicine & General Practice CME/CNE/CPE Audio Podcast
Gil Rabinovici, MD - At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies

PeerView Family Medicine & General Practice CME/CNE/CPE Audio Podcast

Play Episode Listen Later Oct 22, 2024 48:08


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/GBW865. CME/MOC/NCPD/AAPA credit will be available until October 7, 2025.At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

PeerView Clinical Pharmacology CME/CNE/CPE Video
Gil Rabinovici, MD - At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies

PeerView Clinical Pharmacology CME/CNE/CPE Video

Play Episode Listen Later Oct 22, 2024 48:08


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/GBW865. CME/MOC/NCPD/AAPA credit will be available until October 7, 2025.At the Ready for a New Standard of Alzheimer's Care: Preparing Your Practice for the New Era of Amyloid-Targeting Therapies In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

Kultur heute Beiträge - Deutschlandfunk
Vor den Nationalratswahlen in Österreich - "Volkskasperl" + D. Rabinovici i.G.

Kultur heute Beiträge - Deutschlandfunk

Play Episode Listen Later Sep 25, 2024 11:07


Seidel, Änne; Soos, Oliver www.deutschlandfunk.de, Kultur heute

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast
Jonathan E. McConathy, MD, PhD / Gil Rabinovici, MD - Applying Advances in PET Imaging to Facilitate the Early Diagnosis of Alzheimer's Disease: Preparing Nuclear Medicine and Radiology Specialists for New Diagnostic Workflows

PeerView Clinical Pharmacology CME/CNE/CPE Audio Podcast

Play Episode Listen Later Jun 3, 2024 68:52


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/WQE865. CME/AAPA credit will be available until June 15, 2025.Applying Advances in PET Imaging to Facilitate the Early Diagnosis of Alzheimer's Disease: Preparing Nuclear Medicine and Radiology Specialists for New Diagnostic Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

PeerView Neuroscience & Psychiatry CME/CNE/CPE Audio Podcast
Jonathan E. McConathy, MD, PhD / Gil Rabinovici, MD - Applying Advances in PET Imaging to Facilitate the Early Diagnosis of Alzheimer's Disease: Preparing Nuclear Medicine and Radiology Specialists for New Diagnostic Workflows

PeerView Neuroscience & Psychiatry CME/CNE/CPE Audio Podcast

Play Episode Listen Later Jun 3, 2024 68:52


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/WQE865. CME/AAPA credit will be available until June 15, 2025.Applying Advances in PET Imaging to Facilitate the Early Diagnosis of Alzheimer's Disease: Preparing Nuclear Medicine and Radiology Specialists for New Diagnostic Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

PeerView Neuroscience & Psychiatry CME/CNE/CPE Video Podcast
Jonathan E. McConathy, MD, PhD / Gil Rabinovici, MD - Applying Advances in PET Imaging to Facilitate the Early Diagnosis of Alzheimer's Disease: Preparing Nuclear Medicine and Radiology Specialists for New Diagnostic Workflows

PeerView Neuroscience & Psychiatry CME/CNE/CPE Video Podcast

Play Episode Listen Later Jun 3, 2024 68:54


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/WQE865. CME/AAPA credit will be available until June 15, 2025.Applying Advances in PET Imaging to Facilitate the Early Diagnosis of Alzheimer's Disease: Preparing Nuclear Medicine and Radiology Specialists for New Diagnostic Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

PeerView Clinical Pharmacology CME/CNE/CPE Video
Jonathan E. McConathy, MD, PhD / Gil Rabinovici, MD - Applying Advances in PET Imaging to Facilitate the Early Diagnosis of Alzheimer's Disease: Preparing Nuclear Medicine and Radiology Specialists for New Diagnostic Workflows

PeerView Clinical Pharmacology CME/CNE/CPE Video

Play Episode Listen Later Jun 3, 2024 68:54


This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/WQE865. CME/AAPA credit will be available until June 15, 2025.Applying Advances in PET Imaging to Facilitate the Early Diagnosis of Alzheimer's Disease: Preparing Nuclear Medicine and Radiology Specialists for New Diagnostic Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

RESSOURCES
Ygal Rabinovici, de l'amour à la résurrection de sa fille

RESSOURCES

Play Episode Listen Later Feb 29, 2024 49:42


The Lancet Neurology
Marianne Chapleau and Gil Rabinovici on posterior cortical atrophy

The Lancet Neurology

Play Episode Listen Later Jan 22, 2024 21:45


Marianne Chapleau and Gil Rabinovici join Senior Editor Sarah Passey to discuss their research on posterior cortical atrophy. The Article is published in the February issue of The Lancet Neurology.Read the full article:https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00414-3/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneurContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

posterior atrophy cortical rabinovici piis1474
History Behind News
S3E31: Really! Dieting Was A Thing In History?

History Behind News

Play Episode Listen Later Aug 11, 2023 74:48


Medieval Recipes & Eating Right in Renaissance. Ozempic, Wegovy, Mounjaro - expensive weight loss drugs that are all the rage now. Okay, let's get something straight away. In centuries past, diet didn't mean weight loss. In fact, it wasn't until the 18th century that researchers, and later society, began to see fat and obesity as health and, unfortunately, a social issue. Going back to history, what did people eat to stay healthy? That continues to be an important question today. In fact, it consumes many health-conscious people. But it also pertains to weight loss drugs, because experts warn that it's not enough to take Ozempic, Wegovy, Mounjaro. You also have to eat right to stay healthy! So, during the Renaissance, the answer to the above question depended on the type of body you were born with, your constitution. So, are you sanguine, phlegmatic, choleric or melancholic? These psychological terms dictated what best fit your physiology. Dr. Ken Albala, my guest for this episode, is the author of Eating Right in the Renaissance. He is a professor of history at the University of the Pacific, and has written and edited more than 25 books about food and nutrition history, including Cooking in Europe, 1250 to 1650. To learn more about Dr. Albala and his many projects and publications, you can visit his academic and also personal homepage. Obviously, eating right not only helps you lose weight, but, more importantly, it helps you stay healthy and fight the onslaught and progression of many diseases. In a conversation with Dr. Gil Rabinovici, a Distinguished Professor in Memory and Aging, in the Departments of Neurology, Radiology and Biomedical Imaging, at the University of California, San Francisco, I learned that eating right also helps with treating the symptoms of Alzheimer's disease. In that conversation, I asked Dr. Rabinovici why don't we have a cure for Alzheimer's disease. He gave a compelling explanation to that question, and additionally shared some good news - that while we don't have a cure for Alzheimer's Disease yet, we have learned how to live long and productive lives with Alzheimer's. You can listen to my conversation with him here: https://bit.ly/HbN-S2E7s I hope you enjoy these episodes. Adel Host of the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠History Behind News⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ podcast Watch my guests & I ⁠⁠⁠⁠on YouTube⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SUPPORT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here⁠ and join⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ our other supporters in the news peeler community. Thank you.

Neuro[con]Ciencia
#NeuroPsychoClub: ATROFIA CORTICAL POSTERIOR

Neuro[con]Ciencia

Play Episode Listen Later Feb 16, 2023 91:50


Bienvenidos al segundo episodio del programa #NeuroPsychoClub, del canal Neuro[con]Ciencia de la Fundación AISSE [@fundaisse]. Este programa amplía la visión transdisciplinar del canal, incorporando contenido específico del área de #Neuropsicología. En este capítulo, Paula Iglesias entrevista a José Féliz Mozo sobre un caso clínico de una mujer de de 78 años con una clínica que cursa con alteraciones visuales, perceptivas, visoespaciales y práxicas, correspondientes a una variante denominada Atrofia Cortical Posterior, con la que en ocasiones puede cursar la Enfermedad de Alzheimer y otras enfermedades neurodegenerativas. Recopilamos el inicio del caso desde el proceso de entrevista inicial, anamnesis, reunión con los familiares y estudio de informes médicos. Tras esto, hablamos sobre la valoración neuropsicológica específica centrada en los dominios cognitivos alterados; así como las pruebas administradas y el estudio de signos que ayudaron a establecer el perfil primario de afectación y el diagnóstico neurocognitivo. Analizamos también el correlato neuroanatómico de esta variante y las posibles áreas que pueden encontrarse en hipofuncionamiento asociadas a las funciones de percepción, cognición espacial y praxias. De cara a elaborar el plan de tratamiento, se realiza un estudio pormenorizado de los puntos fuertes con los que cuenta la mujer de este caso clínico, ya que son claves decisivas a la hora de enfocar el abordaje. Vamos hablando sobre algunos ejemplos de sesiones y de objetivos que se fueron trabajando para mejorar funcionalidad y el desempeño cognitivo en vida diaria. Concluimos con algunas impresiones sobre el caso y reflexiones tras una exposición magnífica de la que nos llevamos un gran aprendizaje ¡Queremos agradecer a José Félix Mozo todo lo que nos ha aportado en este capítulo! Os dejamos algunas de las referencias que se han comentado a lo largo del episodio: 1. La referencia sobre si alianza es el ingrediente más efectivo se cita de Wampold pero hace referencias al compendio de: Norcross, J. C., & Lambert, M. J. (Eds.). (2019). Psychotherapy relationships that work: Volume 1: Evidence-based therapist contributions. Oxford University Press. 2. La referencia de Crutch sobre la revisión de la Atrofia Cortical Posterior (ACP) se cita en: Schott, J. M., & Crutch, S. J. (2019). Posterior cortical atrophy. Continuum: Lifelong Learning in Neurology, 25(1), 52. y Crutch, S. J., Schott, J. M., Rabinovici, G. D., Murray, M., Snowden, J. S., van der Flier, W. M., ... & Alzheimer's Association ISTAART Atypical Alzheimer's Disease and Associated Syndromes Professional Interest Area. (2017). Consensus classification of posterior cortical atrophy. Alzheimer's & Dementia, 13(8), 870-884. 3. La referencia sobre apraxia táctil y agnosia de la imagen se citan en Binkofski, F., Kunesch, E., Classen, J., Seitz, R. J., & Freund, H. J. (2001). Tactile apraxia: unimodal apractic disorder of tactile object exploration associated with parietal lobe lesions. Brain, 124(1), 132-144. y Sugimoto, A., Midorikawa, A., Koyama, S., Futamura, A., Hieda, S., & Kawamura, M. (2012). Picture agnosia as a characteristic of posterior cortical atrophy. European Neurology, 68(1), 34-41. 4. Las referencias sobre diferencias de dependencia entre DTA y ACP se citan en: Shakespeare, T. J., Yong, K. X., Foxe, D., Hodges, J., & Crutch, S. J. (2015). Pronounced impairment of everyday skills and self-care in posterior cortical atrophy. Journal of Alzheimer's Disease, 43(2), 381-384. y Ahmed, S., Culley, S., Blanco-Duque, C., Hodges, J. R., Butler, C., & Mioshi, E. (2020). Pronounced impairment of activities of daily living in posterior cortical atrophy. Dementia and Geriatric Cognitive Disorders, 49(1), 48-55. 5. Las referencias sobre diferencias de evolución DTA y PCA: Firth, N. C., Primativo, S., Marinescu, R. V., Shakespeare, T. J., Suarez-Gonzalez, A., Lehmann, M., ... & Crutch, S. J. (2019). Longitudinal neuroanatomical and cognitive progression of posterior cortical atrophy. Brain, 142(7), 2082-2095. 6. La App para leer en ACP: Read Clear App - Making Reading Real y se cita en: Suarez-Gonzalez, A., Ocal, D., Pavisic, I., Peacock, A., Naessens, M., Ahmed, S., ... & Crutch, S. J. (2019). ReadClear: an assistive reading tool for people living with posterior cortical atrophy. Journal of Alzheimer's Disease, 71(4), 1285-1295. 7. La referencia a las 3 rutas dorsales se cita en: Binkofski, F., & Buxbaum, L. J. (2013). Two action systems in the human brain. Brain and language, 127(2), 222-229. 8. Las referencias al perfil neuropsicológico en ACP y pruebas sensibles como dot counting etc se cita aquí: North, C., Desai, R., Saunders, R., Suárez-González, A., Bamiou, D., Costafreda, S. G., ... & Stott, J. (2021). Neuropsychological deficits in Posterior Cortical Atrophy and typical Alzheimer's disease: A meta-analytic review. Cortex, 143, 223-236. Os recordamos que este programa también está disponible en YouTube. Muchas gracias por vuestro apoyo, esperamos vuestros comentarios y que este contenido sea de vuestro interés. Podéis proponer temas para tratar en el programa y contarnos qué os parece el enfoque que estamos dando.

Milborn
Zu Gast: Strache und Rabinovici

Milborn

Play Episode Listen Later Nov 16, 2022 31:40


Seit Jahren halten beschlagnahmte und geleakte Chats das Land in Atem: Von politischen Verwerfungen über Nebenabmachungen und Postenaufteilung – kaum ein Stein blieb auf dem anderen. Nun mussten auch zwei Chefredakteure die Konsequenzen ihres digitalen Austauschs mit der Spitzenpolitik ziehen und traten zurück. Eine zentrale Figur in den Chats und den Abmachungen rund um den ORF nimmt der ehemalige Vizekanzler der FPÖ, Heinz Christian Strache, ein. Corinna Milborn begrüßt ihn zum Thema im Studio. Danach nimmt Schriftsteller Doron Rabinovici bei Corinna Milborn Platz. Der Autor und frischgebackene Träger des Österreichischen Ehrenkreuz für Wissenschaft und Kunst spricht über die Reform des Verbotsgesetzes und freie Meinungsäußerung.

Eureka Street Crypto Podcast
Episode 160 - Is accredited investing a glass ceiling, or a necessary protection? Interview with Mike Rabinovici

Eureka Street Crypto Podcast

Play Episode Listen Later Sep 15, 2022 50:01


In this episode I speak with Mike Rabinovici on the subject of accredited investing.  Is the status of being an accredited investor just another glass ceiling that perpetuates inequality and creates a glass ceiling?  Or does it protect the innocent from all the scams that run rampant in the newly emerging web3 space?  Mike sheds light on the terms and the current situation in the web3 space regarding this subject.  We also zoom out and look at how this affects topics such as web3 ID and DAOs.    You can find Mike on Discord in the BanklessDAO server at ComeBackKid#3480 Twitter: @mikerabinovici  

ANA Investigates
ANA Investigates Biomarkers for Alzheimer's Disease

ANA Investigates

Play Episode Listen Later Mar 22, 2022 20:46


On today's show, we'll focus on the future of biomarkers in Alzheimer's disease. We know that amyloid beta and tau protein deposit long before patients with Alzheimer's develop symptoms. If we could use biomarkers to detect this pathology early, and treat patients early, could we prevent the progression to dementia? Our guests today are leaders in the development of biomarkers for Alzheimer's disease - Dr. Suzanne Schindler, Associate Professor of Neurology at Washington University in St. Louis and Dr. Gil Rabinovici, Professor of Neurology and Radiology at the University of California San Francisco. They'll talk with Dr. Doug Ney of UC Denver about the expanding role of biomarkers in Alzheimer's prevention and treatment. Series 3, Episode 5 Featuring: Guests: Dr. Suzanne Schindler, Washington University at St. Louis & Dr. Gil Rabinovici, University of California at San Francisco Interviewer/Producer: Dr. Douglas Ney, University of Colorado Disclosures: Dr. Schindler disclosed that C2N Diagnostics provided data free of cost for her team to analyze. Dr. Rabinovici disclosed that he leads the New IDEAS study and has received research funding from Avid Radiopharmaceuticals, GE Healthcare, Life Molecular Imaging, Genentech; and is on scientific advisory boards for Eisai, J&J, Genentech, Eli Lilly, and Roche.

Canal Livre
Canal Livre- Crise Internacional

Canal Livre

Play Episode Listen Later Feb 28, 2022 71:23


O Canal Livre deste domingo (27/02/22) discutiu a crise internacional que envolve Rússia e Ucrânia. A origem da disputa e os interesses que estão em jogo. A repercussão internacional, os reflexos na geopolítica e na economia. O papel dos Estados Unidos e da Europa nessa disputa. A história, os personagens e o cenário que se projeta. Os convidados são o ex-embaixador brasileiro nos Estados Unidos, Sergio Amaral e também o PhD em relações internacionais Carlos Gustavo Poggio. O programa também tem participações especiais do professor de relações internacionais Leonardo Trevisan, e do correspondente Yan Boechat, diretamente da Ucrânia. A apresentação é de Adriana Araujo. Participam como entrevistadores os jornalistas Fernando Mitre e Moisés Rabinovici.

History Behind News
S2E7: Alzheimer's, History & Hope... the Long Quest For A Cure...

History Behind News

Play Episode Listen Later Feb 21, 2022 57:37


"Alzheimer's Disease of forgetting was a forgotten disease" for most of the 20th century, says Dr. Gil Rabinovici of UCSF. In this episode, he tells us the history of Alzheimer's disease since its discovery and explains why we have yet to discover the cure for AD. In addition, he describes the innovations that ushered in the modern era of AD research. Dr. Rabinovici shares the exciting goal of his large clinical studies. And after giving us some frightening figures about the projected increase of AD population in the U.S., he ends our discussion with a great message of hope - don't be afraid. You can live a long, functional life with AD. In case you were wondering, the news that we are peeling in this episode is Biogen's ADUHELM AD drug - its exciting promise that failed to materialize, confusing product launch, and highly publicized controversy. To learn more about Dr. Rabinovici, his work and publications, visit his academic homepage. I hope you enjoy this episode and gain some perspective about the history and future of Alzheimer's Disease. Adel Host of ThePeel.news podcast Public Health Series SUPPORT: To continue our free podcast program, we depend on our listeners' support. So please click this link https://anchor.fm/the-peel-news/support and join our other supporters in the news peeler community. Thank you.

Lesart - das Literaturmagazin - Deutschlandfunk Kultur
Zum Tod des österreichischen Schriftstellers Gerhard Roth

Lesart - das Literaturmagazin - Deutschlandfunk Kultur

Play Episode Listen Later Feb 9, 2022 5:52


Rabinovici, Doronwww.deutschlandfunkkultur.de, LesartDirekter Link zur Audiodatei

Lesart - das Literaturmagazin (ganze Sendung) - Deutschlandfunk Kultur

Scholl, Joachim; Rabinovici, Doron; Flitner, Bettin; Kindermann, Kim; Zeh, Miriawww.deutschlandfunkkultur.de, LesartDirekter Link zur Audiodatei

São Paulo de Todos os Tempos
Moisés Rabinovici: histórias de um correspondente internacional #107

São Paulo de Todos os Tempos

Play Episode Listen Later Nov 23, 2021 48:34


Correspondente do Estadão e da Rádio Eldorado no Oriente Médio durante as décadas de 1980 e 1990, o jornalista Moisés Rabinovici fala de suas coberturas internacionais em uma entrevista gravada em 2008 para o São Paulo de Todos os Tempos.

New England Journal of Medicine Interviews
NEJM Interview: Dr. Gil Rabinovici on the FDA's controversial approval of a new treatment for Alzheimer's disease.

New England Journal of Medicine Interviews

Play Episode Listen Later Aug 25, 2021 16:39


Dr. Gil Rabinovici is a professor of neurology at the University of California, San Francisco. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. G.D. Rabinovici. Controversy and Progress in Alzheimer's Disease — FDA Approval of Aducanumab. N Engl J Med 2021;385:771-774. G.C. Alexander and Others. Revisiting FDA Approval of Aducanumab. N Engl J Med 2021;385:769-771.

PlanetaCast
#123 O Adeus de Netanyahu - entrevista com Moisés Rabinovici

PlanetaCast

Play Episode Listen Later Jul 20, 2021 37:08


No dia 13 de junho o Parlamento de Israel encerrou o mandato de Benjamin Netanyahu. Ele esteve 12 anos como primeiro-ministro, nos quais se aproximou de líderes populistas e conservadores, como Donald Trump. Sob seu comando, houve um aumento de ofensivas contra o estado Palestino e a quebra de acordos de paz. Apesar de ser o político israelense mais dominante de sua geração, o ex-primeiro-ministro, de 71 anos, fracassou na formação de um governo após as eleições em 23 de março, a quarta em dois anos. O novo governo israelense, liderado por Naftali Bennett, inclui legisladores de esquerda, de centro e árabes, que ele agrupou com o líder de oposição Yair Lapid. Bennett, de 49 anos, um judeu ortodoxo, será o premiê por dois anos antes de Lapid, um ex-apresentador de televisão, assumir o cargo. Com poucas perspectivas de progresso em relação à resolução do longo conflito com Israel, muitos palestinos provavelmente continuam impassíveis com a mudança de governo, dizendo que Bennett irá provavelmente seguir a mesma agenda de Netanyahu. Para falar sobre essa mudança de governo em Israel, O Planeta Azul conversou com Moises Rabinovici, jornalista especialista no Oriente Médio e correspondente internacional do jornal O Estado de São Paulo. Ele fala sobre os motivos dessa coalização inédita para retirar Netanyahu do poder, o julgamento por corrupção do ex-primeiro ministro e as perspectivas para a região com essas mudanças.

GeriPal - A Geriatrics and Palliative Care Podcast
All things Amyloid, including Aducanumab and Amyloid PET scans with Gil Rabinovici

GeriPal - A Geriatrics and Palliative Care Podcast

Play Episode Listen Later Apr 15, 2021 53:10


There are no currently approved disease modifying drugs for Alzheimer's disease, but in a couple months that may change.   In July of 2021, the FDA will consider approval of a human monoclonal antibody called Aducanumab for the treatment of Alzheimer's disease.  If approved, it will not only make this drug the defacto standard of care for Alzheimer's disease, but will create a monumental shift in the usage of other currently limited diagnostic tests, including Amyloid PET scans and other biomarkers. On today's podcast, we talk about all things Amyloid, including Aducanumab and Amyloid PET scans with Gil Rabinovici.  Dr. Rabinovici is the Edward Fein and Pearl Landrith Endowed Professor in Memory & Aging at UCSF.    I could talk to Gil all day long, but we try to fit all of these topics in this jam-packed podcast: The heterogeneity of dementia and potentially Alzheimer's disease Where are we now with disease modifying treatments for Alzheimer's disease The Role of Amyloid PET scans and other biomarkers both now and in the future The wild story Aducanumab and the controversy surrounding its pending FDA approval

DEALER TALK
Steve Rabinovici - Leveraging the SBA During these Times

DEALER TALK

Play Episode Listen Later Oct 13, 2020 33:35


Welcome Back! I am so excited about this session. I sit down with Steve Rabinovici, chairman of the business funding group to talk about the SBA and in particular how you can leverage this information. Right now there is a lot of opportunity for those who are looking at the market the right way. Make sure to tune-in and learn if this can be what you have been waiting for to level up! Time Highlights: 2:15 What is the SBA 06:00 How the financial landscape has changed in lending 14:00 Is now a good time to expand? 18:00 The impact of cashflow 31:25 Next 5 years and why How to connect with Steve and SBA funding: LinkedIn: https://www.linkedin.com/in/stevenrabinovici/ Phone Number: 407 920 6717 Email: steve@sbaloangroup.com SBA Funding Contact Phone Number: 646.699.1400 SBA Funding Email Adress: https://sbafunding.com/ Also, don’t forget to check us out at our website and on the following platforms: Facebook: https://www.facebook.com/Dealertalk/ Instagram: https://www.instagram.com/dealertalk/ YouTube: https://www.youtube.com/channel/UCFzze5QDo48HAS2K1kc83Tg?view_as=subscriber Twitter: https://twitter.com/TalkDealer LinkedIn: https://www.linkedin.com/in/herb-r-anderson-mba%F0%9F%8E%99-503546b/ Thank you for tuning in and as usual, we will TALK later!

Podcast Jüdische Geschichte
EP27: Literarischer Abend mit Doron Rabinovici und SAID

Podcast Jüdische Geschichte

Play Episode Listen Later Sep 23, 2020


In dieser Folge präsentieren wir Ihnen eine Literaturlesung, die in München in der Bayerischen Akademie der Wissenschaften am 16.1.2020 stattfand. Im Rahmen einer Konferenz zu Juden und Muslimen in Deutschland sollten der israelisch-österreichische Schriftsteller Doron Rabinovici aus Wien sowie sein deutsch-iranischer Kollege SAID aus München aus ihren Werken lesen. Leider musste Rabinovici aus gesundheitlichen Gründen absagen. Sein Werk wurde aber von Prof. Michael Brenner vorgestellt. Moderiert wurde die Lesung von Olga Mannheimer. Nach der Lesung der beiden Kurzgeschichten kam es zu einem spannenden Austausch darüber, inwiefern Literatur zur Annäherung verschiedener Religionen und Kulturen beitragen kann. Die Konferenz wurde von der Abteilung für Jüdische Geschichte und Kultur an der LMU zusammen mit dem Leo Baeck Institut, der Bayerischen Akademie der Wissenschaften sowie dem Zentrum für Antisemitismusforschung der TU Berlin organisiert. Finanziell unterstützt wurde diese von der Fritz Thyssen Stiftung für Wissenschaftsförderung. Neben einigen Audiomittschnitten hier im Podcast werden ausgewählte Beiträge der Konferenz zu „Juden und Muslime in Deutschland vom frühen 19. Jahrhundert bis heute“ nun auch im neuesten Band der Münchner Beiträge für Jüdische Geschichte und Kultur veröffentlicht: https://www.jgk.geschichte.uni-muenchen.de/muenchner-beitraege/index.html (Band 2020/2 - vorraussichtliche Veröffentlichung im Oktober 2020).

PaperPlayer biorxiv neuroscience
Connectome-mediated prediction of future tau-PET burden in Alzheimer's disease

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Aug 12, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.11.246496v1?rss=1 Authors: Damasceno, P. F., La Joie, R., Shcherbinin, S., Southekal, S., Kotari, V., Higgins, I. A., Rabinovici, G. D., Mintun, M. A., Raj, A. Abstract: Alzheimer's Disease (AD) tau pathology originates in the brainstem and subsequently spreads to the entorhinal cortex, hippocampus and finally to temporal, parietal and prefrontal association cortices in a relatively stereotyped progression. Current evidence attributes this orderly progression to trans-neuronal spread of misfolded tau protein along the projection pathways of affected neurons. The aggregation of tau is being increasingly recognized as a trustworthy biomarker preceding the appearance of Alzheimer's disease (AD) symptoms. One major goals of disease modifying therapies has been to stop or slow down the tau aggregation process. In order to evaluate drug efficacy, it would be desirable to have an accurate model predictive of a patient's future tau burden, against which the tau measurements from drug-receiving cohorts could be compared. Here we report the development of such a model, evaluated in a cohort of 88 subjects clinically diagnosed as Mild Cognitively Impaired (MCI = 60) or Alzheimer's disease (AD = 28) and tracked over a period of 18 months. Our approach combined data-driven and model-based methodologies, with the goal of predicting changes in tau within suitably specified target regions. We show that traditional statistical methods, allied to a network diffusion model for tau propagation in the brain, provide a remarkable prediction of the magnitude of incremental tau deposited in particular cortical areas of the brain over this period (MCI: R2 = 0.65+-0.16; AD: R2 = 0.71+-0.11) from baseline data. Our work has the potential to greatly strengthen the repertoire of analysis tools used in AD clinical trials, opening the door to future interventional trials with far fewer sample sizes than currently required. Copy rights belong to original authors. Visit the link for more info

Trendcast
#3 Márcio Jucá | Alta Performance de Tráfego Global

Trendcast

Play Episode Listen Later Jun 2, 2020 69:14


Atualmente Diretor de Mídia da agência Rabinovici and Associates em Miami. Ele é engenheiro de produção formado pelo UFF (Universidade Federal Fluminense) com pós graduação em marketing pela Universidade da Califórnia Los Angeles e MBA pela Universidade da Califórnia San Diego. Responsável pelo sucesso de diversas campanhas B2C on-line para clientes como a Rede de hotéis Ramada, Howard Johnson, Baymont and Wyndham. Atualmente lidera campanhas para Microsoft, HP, Motorola entre outras grandes marcas mundiais. Que prazer em conversar com meu amigo Marcio Jucá Barros diretamente de Miami na Flórida! Um bate papo incrível com tendências mundiais no mercado de anúncios! #trend #trendcast #podcast #trafego #performance #leads #eua #brasil Gostou? Quer saber mais? Quer falar sobre? Só chamar direto via WhatsApp. www.trendmarket.com.br | Instagram | LinkedIn

Das Gespräch | rbbKultur
Shoshana Rabinovici - Dank meiner Mutter

Das Gespräch | rbbKultur

Play Episode Listen Later Aug 7, 2019 47:15


Als Zehnjährige wird Schoschana Rabinovici ins Ghetto ihrer Heimatstadt Wilna getrieben, sie durchleidet Konzentrationslager und Todesmarsch. Dass sie als Kind die Torturen überhaupt überlebt, verdankt sie ihrer Mutter. Am 2. August ist Schoschana Rabinovici in Tel Aviv gestorben. Hier können Sie das Gespräch vom 26. April 2015 nachhören.

interview dank dass mutter diskussion tel aviv ghetto meiner biographie todesmarsch rabinovici geschichte 3. reich persönliches schicksal gespräch
Fehl am Platz
Bisschen mehr Gryffindor! | FehlamPlatz 13

Fehl am Platz

Play Episode Listen Later Jul 27, 2019 104:17


Weiter geht es zusammen mit unserem Gast Paul um das Thema Angst. Dabei ist uns wirklich eine ganze Menge dazu eingefallen. UNSER GAST Paul, 50% von „u ltralativ“ und „Doppeldenk“: Ultralativ: https://www.youtube.com/channel/UCb-cM927p9tWkqmpOrBabOQ Doppeldenk-Podcast: https://soundcloud.com/doppeldenkpodcast EMPFEHLUNGEN „A Little Something“-Podcast unter: https://alittlesomething-podcast.de Antilopen Gang über ihren Song „Déjà-vu“: https://www.youtube.com/watch?v=Y5gUpztmJOc Bollnow, Otto Friedrich (1995/2009): Das Wesen der Stimmung. Konigshausen & Neumann GmbH. Wiesbaden „Eine Reihe betrüblicher Ereignisse“, eine Netflixserie Ethymologie von Angst unter: https://www.dwds.de/wb/Angst „Große Völker 2: Die Germanen“ in der ZDFmediathek: https://www.zdf.de/dokumentation/terra-x/grosse-voelker-die-germanen-100.html Kerr, Judith (1971): Als Hitler das rosa Kaninchen stahl. „phosphorescentsite“ (Blog), online verfügbar unter: https://phosphorescentsite.wordpress.com/tag/theres-such-a-long-history-of-using-jewish-coded-features-to-signify-villains/ Rabinovici, Suzanne-Lucienne (1994): Dank meiner Mutter. Remarque, Erich Maria (1989): Im Westen nichts Neues. Aufbau Verlag, Berlin. Richter, Hans Peter (1961): Damals war es Friedrich. ­­­­­­­­ Schollak, Sigmar (1978): Das Mädchen aus Harrys Straße. Kinderbuchverlag Berlin. Spielberg, Steve (1993): Schindlers Liste. Wikipedia: https://de.wikipedia.org/wiki/Schindlers_Liste Thread über Aromantik von @epicLouT: https://twitter.com/epicLouT/status/1151155083746455552 Wicki, Bernhard (1959): Die Brücke. Wikipedia: https://de.wikipedia.org/wiki/Die_Brücke_(1959) „Writing with Color“ (Blog), online verfügbar unter: https://writingwithcolor.tumblr.com/post/154777574613/the-independent-jew-so-many-miles-to-go MUSIK Antilopen Gang (2014): Déjà-Vu. Online verfügbar unter: https://www.youtube.com/watch?v=bxhNuno7myo Billie Eilish (2019): Bury a Friend. Online verfügbar unter: https://www.youtube.com/watch?v=HUHC9tYz8ik Fatoni (2019): Ich glaub mit mir stimmt was nicht. Online verfügbar unter: https://www.youtube.com/watch?v=yYGKXS-Kkl4 Finneas (2019): I lost A Friend. Online verfügbar unter: https://www.youtube.com/watch?v=3mMVcCMO_Ng Idles (2018): Danny Nedelko. Online verfügbar unter: https://www.youtube.com/watch?v=QkF_G-RF66M Juse Ju (2015): German Angst. Online verfügbar unter: https://www.youtube.com/watch?v=l9xG4J--_D8 Die Orsons (2019): Schneeweiss. Online verfügbar unter: https://www.youtube.com/watch?v=wr2JSM-F3Ng Turbostaat (2013): Tut es doch weh. Online verfügbar unter: https://www.youtube.com/watch?v=IP33GgLEWS4 8 Letters (2018): Why don´t We. Online verfügbar unter: https://www.youtube.com/watch?v=C3DlM19x4RQ Zugezogenen Maskulin (2015): Oranienplatz. Online verfügbar unter: https://www.youtube.com/watch?v=iNKQXWsuqx8 Unsere Playlist auf Spotify: https://open.spotify.com/user/1148827511/playlist/1z0DQDCLxvvKVICF2kuEr9?si=854a2Z-1TZqe1S020Zjddw WIR Mail: info@fehlamplatzpodcast.de Twitter: @Fehlam_Platz Instagram: @fehlam_platz Patreon: https://www.patreon.com/FehlamPlatz

FALTER Radio
Episode 33: Doron Rabinovici über die Nationalbibliothek

FALTER Radio

Play Episode Listen Later Feb 23, 2018 17:17


Das heutige FALTER Radio ist der Österreichischen Nationalbibliothek gewidmet. Einen Marktplatz der Erinnerung nennt der Schriftsteller Doron Rabinovici bei seiner Jubiläumsrede die altehrwürdige Institution. Rabinovici spricht über die Welt der Bücher als Ort der Vielsprachigkeit und der Weltoffenheit, immer wieder im Kontrast zu reaktionären Zeiten. Er erinnert an die Auswirkungen Bücherverbrennung der Nazis und die Symbolbedeutung des Heldenplatzes in Wien, an dem Hitler 1938 seinen Einzug gefeiert hat und der in der jüngsten Vergangenheit wiederholt von der demokratischen Zivilgesellschaft für sich in Anspruch genommen wurde. Doron Rabinovicis Rede wurde am 25. Jänner 2018 bei der Eröffnung der 650. Jubiläumsausstellung der Österreichischen Nationalbibliothek gehalten und exklusiv dem FALTER Radio zur Verfügung gestellt. See acast.com/privacy for privacy and opt-out information.

Brain Channel (Audio)
Soccer The Brain and CTE

Brain Channel (Audio)

Play Episode Listen Later Oct 19, 2017 2:06


Dr. Gil Rabinovici explores CTE, a progressive disorder with symptoms appearing years to decades after exposure to repetitive mild traumatic brain injury (concussions and sub-concussive). Rabinovici discusses CTE's occurrence in the world's most popular sport, soccer. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 33036]

Brain Channel (Video)
Soccer The Brain and CTE

Brain Channel (Video)

Play Episode Listen Later Oct 19, 2017 2:06


Dr. Gil Rabinovici explores CTE, a progressive disorder with symptoms appearing years to decades after exposure to repetitive mild traumatic brain injury (concussions and sub-concussive). Rabinovici discusses CTE's occurrence in the world's most popular sport, soccer. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 33036]

Mini Medical School for the Public (Audio)

Dr. Gil Rabinovici explores CTE, a progressive disorder with symptoms appearing years to decades after exposure to repetitive mild traumatic brain injury (concussions and sub-concussive). Rabinovici discusses CTE's occurrence in the world's most popular sport, soccer. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 33036]

Mini Medical School for the Public (Video)

Dr. Gil Rabinovici explores CTE, a progressive disorder with symptoms appearing years to decades after exposure to repetitive mild traumatic brain injury (concussions and sub-concussive). Rabinovici discusses CTE's occurrence in the world's most popular sport, soccer. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 33036]

Bindannmalwech
Ausgabe 1: Alles von ihm gelernt

Bindannmalwech

Play Episode Listen Later Jan 6, 2011 34:53


Mit dem Flugzeug und dem Internet spielen zwei schnelle Medien eine Hauptrolle im Roman »Andernorts« des 1961 in Tel Aviv geborenen Schriftstellers und Historikers Doron Rabinovici – weil Menschen und Informationen damit schneller anderswohin gelangen als mit dem Schiff oder dem Brief. Rabinovici berichtet von Neuigkeiten im Sprechen über die Vergangenheit, über die Unterschiede von historischem und literarischem Erinnern, über neurophysiologische Erzähl- phantasien und Tarantinos Film »Inglorious Basterds«. Abschließend geht die erste Lieferung der Kolumnenserie »Things We Found In The Funhouse« der Frage nach, wie eine fast vergessene Kinderschallplatte ein erwachsenes Leben bestimmen kann.