Podcasts about Focal

「＜ヘッドフォン祭mini＞Astell&Kern最新DAP「SP4000T」など国内初披露モデルを多数展示／LUXMAN・FOCALはハイエンド試聴環境を訴求」　本日7月18日（土）に「夏のヘッドフォン祭 mini 2026」が、東京・丸の内のステーションコンファレンス東京6Fで開催。本稿では、Astell&KernやNoble Audio、SENDY AUDIOなどを展開するアユートブースと、LUXMAN／FOCALブースの模様を紹介する。

Can focal therapy truly “thread the needle” between active surveillance and radical prostate cancer treatment? In this episode of BackTable Urology, host Dr. Tiwa Akinsola is joined by Dr. George Schade from the University of Washington to explore focal therapy as a middle ground between active surveillance and radical treatments. Dr. Schade reviews non-radiation energy modalities including HIFU, TULSA/HI-DU, cryotherapy, and irreversible electroporation, highlighting patient selection, institutional experience, technical nuances, and quality-of-life outcomes from recent trials. --- Get the BackTable apphttps://www.backtable.com/app --- Timestamps00:00 - Introduction02:09 - Overview of Focal Therapy Modalities04:46 - Deciding Between HIFU and IRE06:56 - Evidence and Trials09:40 - Counseling Patients on Outcomes12:09 - Building a Focal Therapy Program16:12 - Navigating Insurance and Appeals21:48 - Managing Large Glands And TURP25:12 - Preop Workup Essentials and OR Workflow32:32 - Overcoming the Learning Curve35:52 - PostOp Recovery and Surveillance39:04 - Options for Managing Recurrence42:44 - Challenges with Repeat Ablation44:56 - Final Takeaways --- More about this episodeThe conversation covers candidate selection and confirmatory biopsy, perioperative technique and recovery, and ongoing surveillance with PSA, MRI, and biopsy. Dr. Schade also discusses challenges with insurance approvals, building a focal therapy practice, and options for managing recurrence, including repeat ablation, surgery, or radiation. The episode examines how to balance cancer control with quality of life and reviews the evolving evidence base supporting focal therapy's role in prostate cancer treatment. --- Resources Irreversible Electroporation for Prostate Tissue Ablation in Patients with Intermediate-risk Prostate Cancer: Results from the PRESERVE Trial:https://www.sciencedirect.com/science/article/pii/S030228382500346X Focal therapy of localized prostate cancerhttps://pubmed.ncbi.nlm.nih.gov/35996758/ Focal Therapy for Prostate Cancer: Available Technologies, Patient Selection, Follow-Up Protocols and Reported Outcomeshttps://pubmed.ncbi.nlm.nih.gov/41339218/ --- BackTable Urology is the go-to podcast for urologists, urologic oncologists, and urogynecologists. Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.► https://www.backtable.com/app

In this episode of The Penis Project Podcast, Melissa is joined by Dr Eve Tiong, a radiation oncologist with Icon Cancer Centre in Western Australia, for a deep dive into how prostate radiotherapy has changed and why many of the horror stories people associate with radiation no longer reflect modern practice.  Dr Tiong walks through the shift from older, broad-field radiation techniques to today's highly targeted approach, explaining how image guidance and modulated delivery now concentrate dose on the prostate while sharply reducing exposure to the bladder and bowel. She and Melissa unpack what this means in practical terms for urinary, bowel and sexual side effects, and discuss how rectal spacer gel is helping to protect bowel function during treatment.  The conversation also covers how patients and their clinicians weigh up surgery versus radiation, the role of hormone therapy for higher-risk cancers, the difference between external beam radiotherapy and brachytherapy, and the emergence of focal therapy as a less invasive option for carefully selected men. Throughout, Dr Tiong returns to a consistent theme: informed decision-making, honest counselling about trade-offs, and the importance of taking sexual health and quality of life seriously at every stage of the prostate cancer journey.  In This Episode, We Cover  Men on active surveillance who want to understand what triggers a move to treatment  Modern radiotherapy is far more targeted than the broad “four-field box” approach used decades ago, sharply reducing dose to the bladder and bowel  Severe long-term side effects from contemporary radiotherapy now sit below 5%  Rectal spacer gel can further protect the bowel during treatment and dissolves naturally within four to six months  Cure rates for surgery and radiation are equivalent for low-grade and favourable intermediate-risk prostate cancer  Focal therapy, treating only the affected area of the prostate, is now emerging as an option in WA  Sexual health and continence should be part of every prostate cancer conversation, regardless of treatment type  higher-risk cancers  PSA monitoring after treatment, the significance of the 0.2 threshold, and emerging PSMA PET tracers  Reframing relapsed or advanced prostate cancer as a manageable, often chronic condition rather than an immediate death sentence  Key Message from Eve  A cancer diagnosis, including relapse, is not automatically a worst-case outcome. With the range of treatments now available, many men go on to live full, active lives for many years, and ongoing advances continue to expand what is possible.  Resources & Links  https://iconcancercentre.com.au/doctors/eve-tiong/  Steve's YouTube channel – personal stories and practical experience from a prostate cancer survivor: Everyday Prostate Cancer Warrior on YouTube  Book a telehealth appointment with our sexual health nurse practitioners at Restorative Health Clinic  For more information check out our websites www.rshealth.com.au , www.makehardeasy.com.au and www.melissahadleybarrett.com.au   Steve Fisher YouTube link to his Everyday Prostate Cancer Warrior. https://youtu.be/APLm1W8uPBA?si=SfaA9A74GqMNcvUq  Click here to shop the Sompatherapy Pumps: The Touch II Automatic Pump, and the Response II Manual Pump  Click here to watch Melissa's YouTube video: Most Men Use the SOMA VED Wrong | Here's the Correct Way    Book a telehealth consultation with our sexual health nurse practitioners:  Restorative Health Clinic    For more information visit our websites:  www.rshealth.com.au  www.makehardeasy.com.au  www.melissahadleybarrett.com    Need Support?  At Restorative Health Clinic, we support men and their partners with:  Penile rehabilitation after prostate cancer treatment  Erectile dysfunction  Vacuum pump and constriction ring education and prescription  Penile injection therapy  Intimacy and sexual recovery  Partner-inclusive support where appropriate  Practical, evidence-based strategies for rebuilding confidence and function    We offer telehealth consultations Australia-wide and internationally, making it easier for men to access experienced, compassionate support no matter where they live. If Steve's story sounds familiar, we would love to hear from you.    Restorative Health Clinic also has a psychologist-sexologist joining the team. If you are struggling with the emotional or psychological side of erectile dysfunction, prostate cancer recovery, or intimacy, we can support you there too – as an individual or as a couple.    Listen & Subscribe  If you found this episode helpful, please subscribe, rate, and review The Penis Project Podcast. Your feedback helps more men and their partners find these conversations. Search for The Penis Project Podcast on Spotify, Apple Podcasts, or your favourite podcast app.    We also have a free email list for updates, episodes, and resources. You can sign up via our website.     Connect With Us  We love hearing from real people navigating their health. If you would like to share your story or ask a question, get in touch.    Email: admin@rshealth.com.au    Websites:  rshealth.com.au   makehardeasy.com.au  melissahadleybarrett.com    Instagram:  @melissahadleybarrett  @restorativehealth.clinic    YouTube:  Melissa Hadley Barrett    TikTok:  @melissahadleybarrett    Facebook:  Melissa Hadley Barrett  Restorative Health Clinic    LinkedIn:  Melissa Hadley Barrett    TEDx Talk:  Watch on YouTube 

Connection is your greatest multiplier—if you know how to build it right. Enjoy my conversation with David Homan, CEO of Orchestrated Connecting. 3 takeaways: Connection is built, not found. It starts with curiosity, vulnerability, and showing up consistently. Give first—without keeping score. The best relationships aren't transactional… they're intentional. Gratitude compounds. A simple thank you can strengthen a relationship for a lifetime. Most people focus on outcomes. The best focus on people. --- A "Connector of Connectors:" David Homan connects people. His primary skill in life is learning about people, helping them reframe and pitch themselves better, and then creating long-lasting relationships based on the premise that for everyone for whom he connects the dots, they would be described as an action oriented, natural giver with high integrity. His book, Orchestrating Connection, published in 2025 is a USA Best-Seller, and his community of over 2300 global "superconnectors" represents family offices, venture capitalists, impact investors, entertainers, athletes, CEOs/Founders, community organizers, and a myriad of other incredible "occupations" that do little to describe how amazing each individual in this community of communities is. He launched his tech company, SOAR Connect in July 2024 and will be bringing out of beta to change the way we build relationships at scale with trust. How David got here: As a prior non-profit CEO, David raised millions for the arts while running a multi-national, multi-million dollar Foundation that survived near total destruction due to Bernie Madoff, and incubated a social impact film company for the Dalio Family Office. His impact advisory firm, Orchestrated Opportunities, partners with family offices, start-ups, funds, and nonprofits to builds new, structured ecosystems of relationships to strategically scale and expand their growth. Focal areas include mental health, health and wellness, climate change, art, philanthropy, social justice, and investing in women, among others. David is a recognized classical composer whose music can be found by saying "Alexa–please play the music of David Homan" with 7 albums and radio play internationally. His latest project is a film/mini-series focused on a composer who loses his mind to Alzheimer's. He serves as an Advisor to NEXUS, the Catalyst Impact Foundation, Regeneration.VC, and as Board Chair of the Arthur Miller Foundation. Connect with Jon Dwoskin: Twitter: @jdwoskin Facebook: https://www.facebook.com/jonathan.dwoskin Instagram: https://www.instagram.com/thejondwoskinexperience/ Website: https://jondwoskin.com/LinkedIn: https://www.linkedin.com/in/jondwoskin/ Email: jon@jondwoskin.com Get Jon's Book: The Think Big Movement: Grow your business big. Very Big! Connect with David Homan:Website: www.orchestratingconnection.com Instagram: https://www.instagram.com/the_connection_orchestrator/  LinkedIn: https://www.linkedin.com/in/davidrhoman    *E - explicit language may be used in this podcast.

Essex-based cyclist Aidan Spence will be travelling through County Clare as part of a 2,200-mile journey around Ireland celebrating the historic links between Ireland and Essex while raising funds for Irish community organisations in Britain.    The challenge, titled Aidan Cycles for Cedd, aims to raise £2,200, equivalent to £1 for every mile cycled. Funds raised will support St Cedd's GAA, St Cedd's Céilí Band, Cúpla Focal na nGael Chelmsford and the wider work of Chelmsford Irish. He spoke to Alan Morrissey earlier about his trip. Photo (c) Aidan Spence via James Hoctor, Chair of Chelmsford Irish

What happens when you have to grieve the person you love before they've even gone?This week I'm joined by Holly Matthews. Holly is a former actress, TEDx speaker, founder of The Happy Me Project, and was widowed at just 32 when her husband Ross died from grade four brain cancer, leaving her to raise their two young daughters alone.But before any of that, there was a Pimm's promotional job, an instant connection, and a love story that moved at lightning speed. Holly and Ross built a relationship full of adventure, brutal honesty and the kind of laughter that makes two people feel like they're speaking a language nobody else understands.Then came headaches. Anxiety. Focal seizures that were dismissed as panic attacks. Until one scan changed everything.Holly talks candidly about anticipatory grief, watching the person you love slowly disappear while they're still alive, and the impossible conflict of desperately wanting more time while also wanting their suffering to end.We also discuss what good healthcare communication looks like, why Holly later stood in front of a room full of brain surgeons to tell them exactly where they were getting it wrong, and how a single compassionate doctor made all the difference.As always, we don't shy away from the harder conversations. Holly shares what it was like preparing two little girls for the death of their dad, why she chose honesty over euphemisms, and the practical ways she's helped them navigate grief ever since.This is a conversation about love, truth, parenting, neurodivergence, identity, and what it really means to live fully when you've learned just how fragile life is.In this episode we cover:• Falling in love almost instantly and trusting your instincts, even when everyone else thinks you're making a mistake.• The symptoms that were repeatedly dismissed before Ross's brain tumour was finally discovered.• Anticipatory grief and losing someone long before they physically die.• Hospice life, dark humour, and navigating the final weeks together.• Why the way doctors deliver devastating news matters so much.• Raising bereaved children with honesty, curiosity and space to ask every question.• Neurodivergence, masking and building a life that feels authentic after loss.

「＜OTOTEN＞FOCAL PROのスタジオ向け旗艦スピーカーを体験＆LEWITTのマイク、beyerdynamicのヘッドホンもよりどりみどり」　メディア・インテグレーションは現在有楽町・国際フォーラムにて開催中の「OTOTEN」にて、FOCALのスタジオ向けスピーカー、カスタムインストール向けスピーカーのトップライン“UTOPIA”シリーズを披露。なかなかオーディオイベントでは試聴機会の少ない貴重なモデルを体験できる場となった。

Teaching Shakespeare's Theatre of the World (Cambridge University Press, 2025) engages with one of Shakespeare's greatest thought-experiments: How does one navigate the 'theatre of the world'? It invites students to examine how Shakespeare challenges this metaphor's vertical hierarchies in response to shifting understandings of cosmological order. Teachers will find rich contextual frameworks for exploring how Shakespeare envisions 'worlds' as emerging from dynamic variables, raising urgent questions about how identity and justice are environmentally constructed. Focal plays include A Midsummer Night's Dream, As You Like It, Hamlet, Henry V, The Merchant of Venice, and Othello. Each discussion features student centered 'Explorations'. These play-specific classroom activities can also be adapted across Shakespeare's corpus and tailored for both secondary and university-level students. These exercises encourage non-linear critical and creative thinking, inviting students to contemplate big ideas and generate new perspectives about the shared points of contact between Shakespeare's world and their own. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Teaching Shakespeare's Theatre of the World (Cambridge University Press, 2025) engages with one of Shakespeare's greatest thought-experiments: How does one navigate the 'theatre of the world'? It invites students to examine how Shakespeare challenges this metaphor's vertical hierarchies in response to shifting understandings of cosmological order. Teachers will find rich contextual frameworks for exploring how Shakespeare envisions 'worlds' as emerging from dynamic variables, raising urgent questions about how identity and justice are environmentally constructed. Focal plays include A Midsummer Night's Dream, As You Like It, Hamlet, Henry V, The Merchant of Venice, and Othello. Each discussion features student centered 'Explorations'. These play-specific classroom activities can also be adapted across Shakespeare's corpus and tailored for both secondary and university-level students. These exercises encourage non-linear critical and creative thinking, inviting students to contemplate big ideas and generate new perspectives about the shared points of contact between Shakespeare's world and their own. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/literary-studies

Teaching Shakespeare's Theatre of the World (Cambridge University Press, 2025) engages with one of Shakespeare's greatest thought-experiments: How does one navigate the 'theatre of the world'? It invites students to examine how Shakespeare challenges this metaphor's vertical hierarchies in response to shifting understandings of cosmological order. Teachers will find rich contextual frameworks for exploring how Shakespeare envisions 'worlds' as emerging from dynamic variables, raising urgent questions about how identity and justice are environmentally constructed. Focal plays include A Midsummer Night's Dream, As You Like It, Hamlet, Henry V, The Merchant of Venice, and Othello. Each discussion features student centered 'Explorations'. These play-specific classroom activities can also be adapted across Shakespeare's corpus and tailored for both secondary and university-level students. These exercises encourage non-linear critical and creative thinking, inviting students to contemplate big ideas and generate new perspectives about the shared points of contact between Shakespeare's world and their own. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/performing-arts

Teaching Shakespeare's Theatre of the World (Cambridge University Press, 2025) engages with one of Shakespeare's greatest thought-experiments: How does one navigate the 'theatre of the world'? It invites students to examine how Shakespeare challenges this metaphor's vertical hierarchies in response to shifting understandings of cosmological order. Teachers will find rich contextual frameworks for exploring how Shakespeare envisions 'worlds' as emerging from dynamic variables, raising urgent questions about how identity and justice are environmentally constructed. Focal plays include A Midsummer Night's Dream, As You Like It, Hamlet, Henry V, The Merchant of Venice, and Othello. Each discussion features student centered 'Explorations'. These play-specific classroom activities can also be adapted across Shakespeare's corpus and tailored for both secondary and university-level students. These exercises encourage non-linear critical and creative thinking, inviting students to contemplate big ideas and generate new perspectives about the shared points of contact between Shakespeare's world and their own. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/education

Teaching Shakespeare's Theatre of the World (Cambridge University Press, 2025) engages with one of Shakespeare's greatest thought-experiments: How does one navigate the 'theatre of the world'? It invites students to examine how Shakespeare challenges this metaphor's vertical hierarchies in response to shifting understandings of cosmological order. Teachers will find rich contextual frameworks for exploring how Shakespeare envisions 'worlds' as emerging from dynamic variables, raising urgent questions about how identity and justice are environmentally constructed. Focal plays include A Midsummer Night's Dream, As You Like It, Hamlet, Henry V, The Merchant of Venice, and Othello. Each discussion features student centered 'Explorations'. These play-specific classroom activities can also be adapted across Shakespeare's corpus and tailored for both secondary and university-level students. These exercises encourage non-linear critical and creative thinking, inviting students to contemplate big ideas and generate new perspectives about the shared points of contact between Shakespeare's world and their own.

 A Chairde,As June heads towards July the distant beat of your drums is pounding out their rhythm. The marching season for all of the Loyal Orders is well underway and the 12 July is fast approaching. One July, sitting during yet another negotiation, into the early hours with Tony Blair the ratatat of Lambegs sundered the quiet. We paused as he asked if I knew what that was. Yes ,I replied that's the Orangemen.“Jungle drums?” he said.I am minded to remind you that the Battle of the Boyne was fought on the 1st July not the 12th. The date changed in 1752 when the English adopted the Gregorian calendar introduced by Pope Gregory. The war was part of a much wider European conflagration – the Nine Years War. James was backed by the English Aristocracy, by France and by the Irish Catholic aristocracy. William who was James's son-in-law and King of Holland, was backed by the English merchant class, by Pope Innocent X1, by Spain and Germany and by Protestant settlers in Ireland. At its core it was William leading a ‘Grand Alliance' of Europeans to curb the power and expansion plans of the French King.The Pope contributed to Williams expenses and when news reached Rome of the victory there was a Te Deum hymn sang in a “joyous proclamation of praise, thanksgiving and faith.” The Pope was front and centre of it all. So much for No Pope Here!  Bodenstown“To say all in one word, Ireland shall be independent. We shall be a nation, not a province, citizens not slaves.” Wolfe Tone On 28 June Republicans from across the island of Ireland will travel to Bodenstown, County Kildare, to stand in homage at the graveside of Theobald Wolfe Tone, the founder of Irish Republicanism.For those who know of Tone and for those who don't I want to recommend a new publication – Bodenstown: Honouring Wolfe Tone – A Pictorial History – which tells his remarkable and inspirational story and recounts the generations who have travelled to Bodenstown each June to remember and celebrate his life.This new publication profiles Tone and publishes photographs of many of the commemorations that have been held there. The first image of Bodenstown is of Padraig Pearse delivering the oration in June 1913. The Irish Republican Brotherhood had asked Pearse to speak and the event was chaired by veteran Fenian Tom Clarke. Both were executed by the British less than three years later following the 1916 Easter Rising.  Cupla Focal Eile.Another few words í nGaeilge as part of this column's contribution to the effort to use whatever Irish we have even if it is only a wee bit.  Here are a few more bits and pieces to replace their English equivalents.Lá breithe shona duit means Happy birthday to you.  It also sounds really good when sung by a crowd at a birthday gathering. Or even on a one to one basis. Try it. Use the same air as the English version. Tiomaint go curamac means drive carefully. Sliothar is a hurling ball. Tóg go bóg é means take it easy. Slán abhaile means Safe home.  

On today's show, we dive into the cost structure of audio speakers. We start with an article that asks whether 'audiophile' speaker brands are milking you for $20,000. We also read your emails and cover the week's news. News: Important update to your DIRECTV account SVS Auto EQ Room Correction for R|Evolution Subwoofers YouTube TV adds Fox One, Peacock to Primetime Channels store Other: Monoprice Alpha In-Wall Speaker There's never been a better time to grab a new Google TV launcher Are 'Audiophile' Speaker Brands Are Milking You for $20,000 The listeners keep delivering great ideas for show topics. This week Mike LaBorde sent in an article published at headphonesty.com entitled A Former FTC Economist Quit His Job to Prove 'Audiophile' Speaker Brands Are Milking You for $20,000.  The author talks about how a former FTC economist quit his job to design and build affordable high-performance speakers.  He argued that many premium audiophile brands are significantly overpriced because they use similar OEM drivers from the same factories while charging massive markups for branding, cabinets, and dealer margins. We'll break down this article into five points we felt were interesting. The full article is linked and you may want to read it for more details. Many premium audiophile speaker brands rely on the same small group of OEM driver manufacturers (like Sinar Baja/SB Acoustics, SEAS (Scandinavian Electro Acoustic Systems), Scan-Speak, etc.). The same factories and engineering talent supply drivers to both high-end and mainstream brands, even when the final speakers carry vastly different logos and price tags. "Custom" or "proprietary" drivers are often overstated. Most brands customize only the "soft parts" (cone, surround, voice coil) on top of standard off-the-shelf "hard parts" from OEM suppliers, rather than designing and building drivers entirely from scratch. Pricing of speakers — The actual cost of the drivers is a tiny fraction of the retail price. In the Wilson Audio Yvette example, the three drivers cost roughly $530–$580 total, representing only about 2% of the $25,000+ selling price. The vast majority of the cost comes from cabinetry, finish, dealer margins (40-50%), distribution, marketing, and brand prestige, with a typical 5x markup from manufacturing cost to retail. Only a few brands truly manufacture their own drivers in-house. Companies like Focal, KEF, Dynaudio, Paradigm, and Bowers & Wilkins are exceptions. Most premium brands outsource driver production due to the high cost and complexity of vertical integration. High performance doesn't require extreme prices. Former FTC economist Dennis Murphy's Philharmonic Audio proves this by offering well-engineered speakers (like the $850/pair Ceramic Mini using quality SB Acoustics drivers) with minimal overhead, direct sales, and no lavish dealer/showroom costs — challenging the idea that great sound must come with five-figure price tags. The article essentially argues that much of the ultra-premium speaker market is driven more by branding and distribution economics than by revolutionary driver technology. What is the Cost Breakdown of Thousand Dollar Speakers? After going through the previous article we wondered what the actual cost breakdown of Passive bookshelf speakers retailing at $1,000 per pair? ThinkKEF Q series, ELAC Debut Reference, or similar mid to high end consumer hi-fi brands. They balance good performance with accessible pricing.  What follows is our best estimation based on the data we uncovered. If you are in the industry and have better data, please let us know and we will update this analysis. Sources for this analysis include - Audio Science Review, AVS Forum, WhatHifi, headphonesty.com, hubhifi, and a few others.  1. Design & Development (R&D) – Upfront Investment Typical cost: $50,000–$250,000+ for a new model line. Includes acoustic modeling, driver selection/tuning, crossover design, enclosure simulation, multiple prototypes, listening tests, and anechoic chamber measurements. For this price tier, brands often use a mix of off-the-shelf and mildly customized drivers rather than fully bespoke high-end ones.   Amortization: Spread over production volume and for this exercise we used a production run of 5,000–20,000 pairs. This adds roughly $5–$25 per pair at a reasonable scale. 2. Prototyping & Tooling Prototypes: 5–15 iterations at $300–$1,200 each which include custom cabinets, driver samples, hand-assembled crossovers. Tooling: CNC molds/jigs for cabinets, baffle cutting, or vinyl wrap tooling: $8,000–$40,000 upfront. Amortized to $2–$10 per pair. 3. Bill of Materials (BOM) – The Biggest Per-Unit Cost For a typical 2-way passive bookshelf (6.5" woofer + 1" tweeter) at this price point: Drivers - $80–$180 - 6.5" coated paper woofer (~$30–$70 ea.), soft dome or aluminum tweeter (~$15–$50 ea.). Brands like SEAS, SB Acoustics, or custom OEM. Cabinet -  $60-$130, - Braced MDF (18–25mm), vinyl wrap or basic veneer, internal damping, port tube, terminals. Real wood veneer adds premium. Crossover - $30-$80 - 2nd/3rd order with air-core inductors, film capacitors, resistors. Higher quality parts (Mundorf-level) push toward the upper end. Other (grille, wiring, hardware, terminals) - $20-$50 - Magnetic grilles, internal wiring, binding posts. Total BOM per pair: $190–$440 at volume production (typically in China or Vietnam for most brands). Premium touches (better drivers, thicker bracing, nicer finishes) push BOM toward the higher end. 4. Manufacturing, Assembly & Overhead Labor & Assembly: $25–$60 per pair (cabinet gluing/bracing, driver mounting, crossover soldering, final wiring, testing). Quality Control & Testing: Burn-in, frequency sweeps, distortion checks: $10–$25. Factory Overhead/Utilities: $35 - $50. Total Manufacturing per pair: $70 - $135 5. Full Cost Structure to Retail ($1,000/pair) We will assume a large brand that sells 20,000 units and has already invested in tooling and requires minimal new tooling for each new speaker design.  Design and R&D Amortized - $5 Prototype and Tooling  - $2 Bill of Materials - $315 - We split the $190 - $440 down the middle Manufacturing -  $103 - We split the $40 - $135 down the middle Shipping, duties etc to distributor per pair on average - $50 Total to Manufacture $474. The rest of the thousand dollars covers the distribution chain, branding, and profit. And in reality, depending on the efficiency of the factory and ability to leverage design histories from years of experience, the soft costs can be about a third of $110 we came up with, bringing the total cost to about $400. Key Variables Affecting Cost Volume: Higher production = lower per-unit costs. Driver Quality: Exotic materials (beryllium tweeters, carbon fiber) can double driver costs. Cabinet Finish: Vinyl vs. real walnut veneer = big difference. Brand Positioning: Established names (KEF, ELAC) have higher R&D/marketing allocation than direct-to-consumer brands. For comparison DIY builders can replicate similar performance for $300–$600 per pair in parts using higher quality drivers and crossover components and flat-pack or self-built cabinets, eliminating most of the overhead and markups. And after building over 30 sets of speakers I can say without doubt that what you build will sound as good as speakers costing ten times the amount. Plus you can use material that works best for you as well as customizing the look to match your decor. Even my latest set built from stock off the shelf components bought from Part Express for about $200 sound simply amazing!  

In this episode of The Lead, host Sandeep A. Saha, MD, MS, FHRS, is joined by Babak Nazer, MD, and Rajesh Kabra, MD, FHRS, to discuss the journal article, Safety and Effectiveness of a Dual-Energy Focal Ablation Catheter to Treat Paroxysmal Atrial Fibrillation: 6-Month Results of the FlexPulse IDE Study. Together, they review the study's six-month findings and explore the safety and effectiveness of a dual-energy focal ablation catheter for the treatment of paroxysmal atrial fibrillation. Learning Objectives Review the six-month results of the FlexPulse IDE Study evaluating a dual-energy focal ablation catheter for the treatment of paroxysmal atrial fibrillation. Discuss the safety outcomes reported in the study and their implications for clinical practice. Examine the effectiveness findings of the dual-energy focal ablation approach in patients with paroxysmal atrial fibrillation. Podcast Contributors Sandeep A Saha, MD, MS, FHRS  Babak Nazer, MD Rajesh Kabra, MD, FHRS   Host and Contributor Disclosure(s): S. Saha• Honoraria/Speaking/Consulting Fee/Speaker's Bureau: Medtronic, Inc. B. Nazer •Honoraria/Speaking/Consulting Fee: Edwards Lifesciences, Biosense Webster, Inc., Siemens Healthineers •Research: Siemens Healthineers R. Kabra •Honoraria/Speaking/Consulting Fee: AtriCure, Inc., Biosense Webster, Inc., Milestone Pharmaceuticals, AltaThera Pharmaceuticals •Research: Abbott Medical, Medtronic, Inc.  

Signs of focal epilepsy before the seizures start: hear all about it from neurologist and epileptologist Dr. Jacob Pellinen, who shares with us his research and results proving that people can experience things like depression or learning difficulties at school or work before seizure onset.Chapters

As part of the 2026 UCSF Patient Conference on Prostate Cancer, Dr. Matthew Cooperberg discusses focal therapy. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 41553]

As part of the 2026 UCSF Patient Conference on Prostate Cancer, Dr. Matthew Cooperberg discusses focal therapy. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 41553]

As part of the 2026 UCSF Patient Conference on Prostate Cancer, Dr. Matthew Cooperberg discusses focal therapy. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 41553]

Cúpla FocalI often quote the late Seán Mac Goill. Seán was one of the visionaries who gave us the new Bombay Street after the pogroms of 1969, the urban Gaeltacht on Bóthar Seoighe, The Andersonstown News and many other outstanding projects going back to the 1960s. Seán and his peers and their families were immersed in the Irish language and the wider cultural revolution across Belfast. It was they who laid the foundations for today's revival and successes. Seán's name is immortalised in the Gael Ionad Mhic Gioll in Ballymurphy, home of Glór na Móna, the outstanding Irish language organisation. Britain's shameful role in the NakbaOn May 15 Palestinians across Palestine and throughout their diaspora commemorate the ‘Nakba' or the ‘catastrophe' of 1948. In that year Zionist militias commenced a systematic assault on Palestinian towns and villages creating fear and displacement. Massacres occurred daily and in a short time 800,000 Palestinians became refugees in their own place. The Nakba is ongoing. It is taking place now in the west Bank, in Lebanon and in the Gaza Strip.Fianna Fáil – A centenary of failureLast Saturday the Fianna Fáil Ard Fheis in Dublin marked the centenary of that party. At its foundation in 1926 meeting it was agreed that the party would be titled ‘Fianna Fáil – The Republican Party.'Its principal aim was defined as ‘Securing the political independence of a United Ireland as a republic.'That was the basis on which Fianna Fáil first entered government in 1932. But in the decades to follow nothing was done to advance that aim. On the contrary when in government every effort was made to thwart unity, including through the imprisonment and execution of republican political prisoners and the abandonment of nationalists living in the North under an apartheid unionist regime.

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What if I told you that after focal therapy, a normal PSA and a clean MRI can still mean prostate cancer is hiding in plain sight?That's the moment in this conversation that makes you stop—and rethink everything you've been told about “success” after focal therapy.In this episode, we're joined by Abhinav Sidana, MD, MPH, Associate Professor of Urology and Director of Prostate Cancer at University of Chicago Medicine, a nationally recognized urologic oncologist, clinical trial leader, and one of the architects shaping the future of focal therapy. Dr. Sidana has trained at AIIMS, Johns Hopkins, NIH, and now leads one of the most rigorous focal therapy programs in the country—backed by over 100 peer-reviewed publications and multiple active clinical trials.This is not a sales pitch for focal therapy. It's a clear-eyed look at what works, what doesn't, and what we still get wrong.In this episode, you'll learn:✅ Why MRI made focal therapy possible—and why it can still miss clinically significant disease✅ How biopsy strategy—fusion, mapping, or transperineal—directly affects recurrence risk✅ Why PSA is an unreliable signal after focal therapy—and what actually predicts failure✅ How short-term ADT may expand focal therapy to larger or higher-risk tumorsIf you're a patient, clinician, or researcher navigating prostate cancer decisions, this episode will fundamentally sharpen how you think about focal therapy—and its limits.00:00 Can MRI and PSA Miss Significant Cancer After Focal Therapy?04:00 Who Is a Good Candidate for Focal Therapy?06:30 Mapping Biopsies vs MRI Fusion Biopsies09:30 Transperineal vs Transrectal Biopsies11:00 What Is IRE (NanoKnife)?14:30 Who Is NOT a Candidate for Focal Therapy?18:00 Vapor Therapy & TULSA Pro23:00 Should Doctors Use Multiple Focal Therapy Technologies?25:30 Can Higher-Risk Prostate Cancer Be Treated with Focal Therapy?34:00 Does the Type of Energy Matter?37:00 Combining ADT with Focal Therapy40:30 How Tumor Size Impacts Eligibility45:30 Why MRI and PSA Are Imperfect After Treatment49:30 What Is PSA Recurrence After Focal Therapy?53:30 The Future of MRI, AI, and Surveillance57:30 Do Patients Need Repeat Biopsies Forever?___________________________________

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  In this episode, Ray Cochrane leads with Mozilla shipping Firefox 150 with 271 patched bugs found by Anthropic’s Mythos system, the first major real-world deployment of the AlphaGo-Moment cybersecurity tooling. He also covers a 9-year dormant Linux kernel root, a college student stopping Taiwan’s high-speed rail with a software-defined radio, GitHub MCP secret scanning going GA, the NVIDIA NeMo lawsuit surviving its motion to dismiss, the Hugging Face Reachy Mini app store, Anthropic’s Auto Mode for Claude Code, and the 4-gigabyte AI model Chrome silently installed on your computer. – Want to start a podcast? Its easy to get started! Sign-up at Blubrry – Thinking of buying a Starlink? Use my link to support the show. Subscribe to the Newsletter. Email Ray if you want to get in touch! Like and Follow Geek News Central’s Facebook Page. Support my Show Sponsor: Best Godaddy Promo Codes Get 1Password Full Summary Cochrane opens the show with the AlphaGo Moment moving from theory into production. Mozilla shipped Firefox 150 this week with 271 patched bugs that Anthropic’s Mythos system found. Furthermore, the broader episode threads a clear pattern: AI tooling is reshaping security, developer workflows, and consumer software faster than the surrounding ecosystem can absorb it. The show closes on the four-gigabyte AI model Chrome installed on a billion machines without explicit consent. Mozilla Ships 271 Mythos Bugs in Firefox 150 Mozilla ran Anthropic’s restricted Mythos system against the Firefox 150 codebase before shipping. The result: 271 found bugs (180 high severity, 80 moderate, 11 low) baked into the release. However, the bigger number is the year-over-year jump. April 2026 shipped 423 total Firefox security fixes versus 31 a year prior. The breakdown for April: 271 from Mythos, 41 from external researchers, and 111 from other internal sources. Cochrane is sticking to his guns on calling this the AlphaGo Moment for cybersecurity. Skeptics argue Mythos is industrial-scale fuzzing because most found bugs sit in memory-safety territory. However, his counter is the velocity itself. Furthermore, he frames the resistance as carriage-versus-cars: humans-first research still grounds the tool, but throughput is the win. The Firefox CTO put it directly: defenders finally have a chance to win, decisively. For developers asking whether Mythos changes anything if they already run fuzzers, Cochrane’s answer is yes, and not even close. Additionally, he notes Mythos is restricted-access. The broadly available tier is Claude Opus 4.7, which Mozilla used since February before getting onto the restricted program for the Firefox 150 cycle. Run Opus 4.7 first. Sponsor: GoDaddy GoDaddy has been sponsoring this show for over twenty years. Economy hosting starts at $6.99/month, WordPress hosting at $12.99/month, and domains at $11.99. Use codes at geeknewscentral.com/godaddy for exclusive deals and to directly support the show. Copy Fail: 9-Year Linux Kernel Bug, 732 Bytes to Root A 9-year-old dormant Linux kernel bug got disclosed April 29 as CVE-2026-31431. Researchers published a 732-byte Python script that roots every major Linux distribution shipped since 2017. Additionally, CISA added the CVE to its Known Exploited Vulnerabilities catalog on May 1 with a May 15 federal deadline. The bug lives in the kernel’s crypto socket layer through the AF_ALG AEAD interface, originating in a 2017 in-place crypto optimization that lacked bounds checking. Cloudflare published their post-mortem this week. Their first instinct was to remove the kernel module entirely. However, service dependencies forced a workaround instead. Cloudflare resumed normal patched-kernel reboot automation across their 330-city fleet on May 4, with manual reboots and rollouts continuing after. Taiwan Rail Stopped by a 23-Year-Old With a Software-Defined Radio A 23-year-old Taiwanese university student with the surname Lin spoofed a TETRA general alarm signal on April 5, stopping trains on Taiwan’s high-speed rail. The accomplice supplied the radio parameters. Both were arrested by month-end. Lin posted NT$100,000 bail; the accomplice posted NT$80,000. The incident hit at 11:23 PM during the Qingming holiday weekend, stopping three revenue passenger trains plus one deadhead. Furthermore, the system has been in service for 19 years without rotating its cryptographic parameters once. Cochrane notes this is exactly the type of long-dormant infrastructure flaw that Mythos-class tooling catches, if anyone bothers to point it at the wires we already have. GitHub MCP Secret Scanning Goes GA GitHub’s secret scanning in the MCP server hit GA on May 5, with dependency scanning entering public preview the same day. Both released after a seven-week public preview run starting March 17. Additionally, the feature lets MCP-compatible coding agents (Copilot CLI, VS Code, JetBrains, Claude Code, Cursor, Windsurf) detect exposed secrets before commits or pull requests. Findings are ephemeral. They surface only in the current chat session and don’t persist as GitHub alerts. Sources disagree on scope: GitHub’s GA changelog says repo-level or org-level settings work, while the docs say only org-level applies. Cochrane flags the open question of whether MCP prompt injections could be exploited to send discovered secrets elsewhere. Subquadratic Debuts a 12-Million-Token Context Window Miami-based Subquadratic emerged from stealth on May 5 with a $29 million seed round and a reported $500 million valuation. Their model, SubQ 1M-Preview, runs on a new Subquadratic Sparse Attention architecture (their technical writeup calls it Selective Attention; same acronym, different second word). The headline claim: a thousand-times reduction in attention compute at 12 million tokens versus frontier models. However, that figure is vendor marketing math. There is no peer-reviewed paper, no public weights, and no independent benchmark replication. Researchers are demanding independent proof. Furthermore, CTO Alex Whedon’s pull line, “Retrieval / RAG plumbing is a waste of human intelligence,” signals how aggressively they want to position against retrieval-augmented architectures. ChatGPT Goblins, China’s “Catch You Steadily”: Sycophancy Is Universal Last week’s ChatGPT goblin obsession has a Chinese-language twin. The model overuses a phrase translating as “I will steadily catch you.” Additionally, a new Stanford and CMU study called ELEPHANT shows social sycophancy is universal across all 11 LLMs tested with 2,400-plus participants. Models endorsed users 49 percent more than humans did, and 47 percent even on harmful prompts. Alibaba’s Qwen and DeepSeek topped the rankings. Cochrane notes sycophancy is obvious once you’re aware of it but tricky to dissuade. Even with explicit instructions, longer context windows can reintroduce the behavior as the instructions get diluted. Furthermore, the trap is believing you’ve handled it. Once you think you’ve got it under control, you’re more prone to being influenced because you stopped watching for it. NVIDIA NeMo Lawsuit: Judge Tigar Denies Motion to Dismiss Three authors filed Nazemian v. NVIDIA in March 2024, alleging NVIDIA used The Pile and Books3 (approximately 196,640 pirated books) to train its NeMo AI framework. NVIDIA’s defense relied on the Sony v. Universal Betamax doctrine, arguing NeMo’s training scripts are general-purpose tools like a VCR. This week, Judge Tigar denied NVIDIA’s motion to dismiss in the Northern District of California. The headline quote: NeMo’s training scripts “have no other purpose than to speed up the process of infringement.” Furthermore, the judge rejected the VCR analogy outright. NeMo’s scripts are not general-purpose tools; they were allegedly purpose-built to ingest pirated material. Cochrane reads the Betamax framing as legal-jargon arbitrage rather than honest defense. The Humanoid Robot Market Is Smaller Than the Hype Michael Barnard at CleanTechnica argues that scenario-math against the global labor market puts realistic humanoid TAM at $200 billion to $1 trillion, not $20 trillion. Near-term wins cluster in warehouses, not homes. Additionally, the framework weighs dexterity burden against human-proximity safety burden. Real opportunities cluster where both burdens are low. Cochrane connects this to last week’s reservations about humanoids in the household. Furthermore, the risk profile is the issue: these robots aren’t prepared for every scenario, can’t make dynamic decisions, and one software update can change the definition of “safe.” Hugging Face Launches Reachy Mini App Store Hugging Face launched an open-source app store for the Reachy Mini robot this week, $299 for the Lite tethered version and $449 wireless. There are 200-plus community-built apps at launch from over 150 creators, with nearly 10,000 Reachy Minis cumulative shipped. Additionally, apps are forkable, with the default agent (ML Intern) able to modify, write, test, and ship code on any existing app. Examples at launch include an office receptionist built in under two hours, a Reachy Phone Home anti-procrastination app, baby-monitor-style apps, a cooking assistant, and a 78-year-old Joel Cohen’s voice-controlled CEO peer-group app. Pollen Robotics, the company behind Reachy, was acquired by Hugging Face on April 14, 2025. Bebop the Humanoid Robot Delays Southwest Flight 1568 A 4-foot, 70-pound humanoid robot named Bebop delayed Southwest flight 1568 from Oakland to San Diego by more than 73 minutes on April 30. The crew flagged the lithium battery as oversized. Furthermore, the battery was reportedly four times the cabin limit. Bebop belongs to Dallas-based Elite Event Robotics, which bought a full-price cabin ticket because the robot exceeded checked-baggage weight. Bebop danced for passengers at the gate before boarding. However, Southwest had Elite remove the batteries before departure, and replacements were overnighted to Chicago for the next event. Cochrane flags the obvious: batteries have always been flagged in aviation, so forgetting that with a humanoid robot in tow is a strange miss. Ouster Rev8: Native Color Lidar With Google, Volvo, Skydio Stating Intent Ouster announced the Rev8 OS Family on May 4 in San Francisco. The sensors fuse depth and color via SPAD detectors (single photon avalanche diodes) on Ouster’s custom L4 and L4 Max chips. Google, Volvo Autonomous Solutions, Skydio, Liebherr, Epiroc, and PlusAI have stated intent to adopt, though nothing is formally signed. Specs include 48-bit color, 116 dB dynamic range, and pre-fused 3D colorized point clouds. The OS1 Max gets 500-meter max detection. Available to order today and shipping this quarter, with no pricing disclosed. CEO Angus Pacala in his TechCrunch interview: “The goal is to obviate cameras. There’s no reason that one sensor can’t do both.” TagTinker Lets a Flipper Zero Mess With Electronic Shelf Labels A new Flipper Zero app called TagTinker uses infrared signals to push images and text to electronic shelf labels. Additionally, these are the same kind of price tags grocery chains are starting to use for surveillance pricing. The app and GitHub repo went public this week. Maryland’s HB 895, signed by Governor Wes Moore, takes effect October 1 as the first-in-nation surveillance pricing law. It covers food retailers and third-party food delivery service providers. Furthermore, ESLs use the same IR signaling as TV remotes with weak security. The dev’s disclaimer states it’s strictly for educational research, security curiosity, and displaying digital art on hardware you legally own. Fitbit App Becomes Google Health, Plus Fitbit Air, Plus Google Fit Sunset Google announced May 7 that the Fitbit app becomes Google Health on May 19, rolling through May 26. The launch ships with the new $99.99 Fitbit Air screenless tracker and the long-rumored Google Fit shutdown. Additionally, the four-tab interface (Today, Fitness, Sleep, Health) bundles a Gemini-powered AI Health Coach. Coach is premium-gated at $9.99/month or $99/year. Medical records integration is US-only at launch. The Fitbit Air gets up to one week of battery life and 50-meter water resistance. However, Cochrane flags conflicting privacy framing: Google’s AI summary bullets say “your data stays private,” but the actual document copy says only “committed to not using Fitbit user health and wellness data for Google Ads.” Those are not the same statement. Russinovich on Why Win32 Won and WinRT Didn’t Microsoft Azure CTO Mark Russinovich said via Microsoft Dev Docs video that Win32, the 1995 API, is still foundational to Windows 11. WinRT, the modernization replacement, “didn’t play out the way a lot of people expected.” Mostly clickbait framing per Windows Latest, but the substantive angle is real. Microsoft is pivoting back to native WinUI 3 development after years of pushing developers toward WebView2 and Electron. Additionally, Electron-based apps are known for insane RAM usage, and everyone is hurting for RAM right now. Furthermore, the bigger open question is whether Electron survives the test of time, especially with the React engine reportedly being rewritten in Rust. “Tabula Plena”: The Brain Starts Full, Not Blank A Nature Communications study from the Institute of Science and Technology Austria found that the mouse hippocampal CA3 recurrent network begins densely connected and refines through pruning. ISTA’s press release frames this as “tabula plena,” meaning full slate, counter to tabula rasa. The paper published April 21. First author Victor Vargas-Barroso and senior author Professor Peter Jonas studied mice at three developmental stages. Furthermore, the “starting overloaded enables faster sensory integration” framing is Jonas’s hypothesis from the press release, not a paper conclusion. Cochrane closes on the bigger question: did we have human growth and experience mapped wrong from the start? The Aqueous Battery You Can Pour Down the Drain A Chinese research team led by Professor Chunyi Zhi at City University of Hong Kong built an aqueous battery using a custom organic polymer electrode plus neutral magnesium and calcium salts (food-grade tofu coagulants) as electrolyte. Published in Nature Communications on February 18. Numbers to know: 120,000-plus charge cycles, full-cell energy density of 48.3 watt-hours per kilogram. That’s well below typical lithium-ion. However, post-cycling analysis showed only magnesium, calcium, chlorine, carbon, and copper, with no heavy metals. The cell complies with US RCRA, ISO 14001, and China’s GB 18599-2020 for direct environmental disposal. Additionally, the “300-plus years” framing is journalists extrapolating from the 120,000 cycles, not a paper claim. ResoNix Klippel Tests Expose Car-Audio Spec Lies Nick Apicella, founder of ResoNix Sound Solutions in Stony Point, New York, spent around $23,000 on independent Klippel LSI and TRF testing of 40 subwoofers. He published 21 results showing widespread misrepresentation of Xmax (excursion) and thermal/power-handling claims. Test data published in three batches between December 2025 and January 2026. Specifics: Wavtech thinPRO12 claimed 20 mm of excursion but delivered 8.85 mm, scoring 15 out of 100 on marketing accuracy. One driver hit 44 percent of advertised excursion. Another tripped thermal protection at half its rated power. Additionally, nine of 21 drivers scored below 50 out of 100. Brands tested include JL Audio, Sundown, Focal, Morel, Audiofrog, Adire, Stereo Integrity, and Dynaudio. Conflict-of-interest flag: ResoNix’s own GUS-15, 12, and 10 prototypes conveniently rank one, two, three. JetBrains Opens 2026 Developer Ecosystem Survey JetBrains opened the 10th annual Developer Ecosystem Survey this week. It takes about 30 minutes, with prizes including a MacBook Pro 16-inch and a $1,000 Amazon gift card. Anonymized raw data is published publicly, and cumulative scale is 100,000-plus developers across recent years. Additionally, the survey is going fully anti-AI: “evil bots, dishonest respondents, and AI agents will be excluded from prize distribution.” Cochrane is curious whether TypeScript holds its 2025 crown after knocking Python off, and whether Rust shows real growth given the wave of LLM-driven Rust rewrites in the past few months. Anthropic’s Claude Code Auto Mode Goes Live Anthropic launched Auto Mode for Claude Code roughly six weeks ago. Claude Code’s previous behavior required user approval for most file modifications and command executions, generating heavy approval-fatigue complaints during longer sessions. Auto Mode is the answer: Claude can run multi-step development tasks without per-action approval. Additionally, the architecture is a two-stage classifier, with stage one a fast yes/no filter and stage two doing chain-of-thought on flagged actions. Cochrane runs his own Claude Code in YOLO mode but with custom rejection rules baked into settings to block commands he doesn’t want, even with skip-permissions on. He recommends configuring settings as the actual policy layer rather than relying on classifier judgment alone. Furthermore, recent posts about Claude deleting websites or wiping production databases reinforce why the settings layer matters more than the auto-mode toggle. Chrome Quietly Installed a 4GB AI Model on Your Computer Google Chrome silently downloads on-device AI model weights (Gemini Nano family) to a `weights.bin` file in the OptGuideOnDeviceModel directory, around four gigabytes in Alexander Hanff’s audit. Furthermore, the model re-downloads if you delete it. Hanff timed his own install at 14 minutes 28 seconds on macOS. Affected platforms include Windows, macOS (including Apple Silicon), and Linux. Hanff frames this as a multi-front legal violation: a direct breach of Europe’s ePrivacy Directive, two articles of GDPR, and an environmental harm of a magnitude that would be notifiable under the Corporate Sustainability Reporting Directive. At one billion users, the four-gigabyte distribution represents roughly 240 gigawatt-hours of network and storage energy paired with about 60,000 tonnes of CO2-equivalent emissions. However, no EU regulator action or formal complaint has surfaced as of this episode. The model powers on-device features (email writing, scam detection, summarization, smart paste, tab grouping) but not the visible AI Mode button, which routes to the cloud. To disable, Cochrane recommends Chrome Settings, then System, then On-device AI, toggle to off. Two more paths exist via `chrome://flags` or a Windows registry edit. Cochrane closes the show with show housekeeping: GNC Insider at geeknewscentral.com/insider, email at geeknews@gmail.com, newsletter signup at geeknewscentral.com, and Pocket Casts as a solid modern podcast app pick. Have a wonderful night. The post Mozilla Meets Mythos #1864 appeared first on Geek News Central.

Today we discuss the iPhone camera's focal lengths. What are they and why do we care? We'll also look at which ones to use in certain situations. Plus, we have something very cool to tell you about and you won't want to miss it.Jack Hollingsworth's MaterclassBuy Me a CoffeeVoicecastGreg's BookThe Podcast WebsiteDave on InstagramDave on ThreadsDave on BlueskyDave on XDave on TikTokDave on VERODave on MastodonDwight on FlickrDwight on VERODwight on GlassDwight on InstagramDwight's Art on InstagramDwight on VSCOGreg's WebsiteGreg on GlassGreg on About.meGreg on InstagramGreg on VEROGreg on FlickrGreg on XThe Podcast YouTube ChannelShayne Mostyn's YouTube ChannelSmartphone Photography TrainingThe iPhoneography Podcast Facebook GroupShayne Mostyn's Bloody Legends Facebook GroupRick Sammon's Smartphone Photo Experience Facebook GroupReeflex's Facebook GroupiPhone 17 Pro & Pro Max PhotographyGet your first year of Glass for $20: https://glass.photo/offer/gregReeflex Lenses - Get 10% off Reeflex lenses with the coupon code 10%OFFGREG

Recorded from the show floor at AXPONA 2026, eCoustics Editor in-Chief Ian White shares a straightforward take on what he saw and heard across the show. This episode covers the systems and brands that delivered, including QUAD, ATC, DeVore Fidelity, Advance Paris, Focal, Michell, Unison Research, TEAC, Amphion, and Dynaudio, along with a look at rooms and products that were less convincing. It is an honest assessment of what worked in real listening conditions, what felt overpriced, and how the gap between performance and cost continues to shape the high-end audio market.Sponsor: Please check out the latest SVS subwoofers, speakers and more at svsound.com.Panel:Ian White, eCoustics Editor-in-ChiefMitch Anderson, Co-Host & eCoustics Podcast ProducerBrian Mitchell, Co-Host & eCoustics Founder & CEOCredits:Original intro music by The Arc of All. https://sourceoflightandpower.bandcamp.comVoice Over Provided by Todd Harrell of SSP Unlimited. https://sspunlimited.comProduction by Mitch Anderson, Black Circle Studios. https://blackcircleradio.com#ecoustics #axpona2026

Dave McColl is Executive Director of Stanford Climate Ventures (SCV), a program designed to help students build climate companies through rigorous go-to-market strategy and hands-on company building. SCV is a project-based course at Stanford University that has helped launch dozens of startups across energy, infrastructure, and industrial decarbonization. In this episode of Inevitable, Yin Lu, General Partner at MCJ,  sits down with McColl to unpack the SCV playbook—from “earned secrets” to the importance of customer discovery. The conversation also features three founders who came out of the SCV ecosystem: Carla Pinzon, Founder of Expand Power, solid-state transformers for a more flexible grid Raj Tilwa, Founder of Focal, personalized heating systems for commercial spaces Nico Pinkowski, Founder of Nitricity, decentralized fertilizer with air, water, and renewable power Together, they share how SCV shaped their companies, from early pivots and customer insights to product-market fit, and what it takes to build sustainable businesses.  Episode recorded on March 13, 2026 (Published on April 14, 2026). In this episode, we cover:  (0:00) An overview of Stanford Climate Ventures (SCV) (5:12) The origin of SCV and its community-driven model (10:14) How SCV works: discovery, iteration, and “earned secrets” (16:25) The biggest founder mistake: ignoring the customer (18:56) What predicts success: discovery volume and team dynamics (25:51) Carla Pinzon (Expand Power): solid-state transformers for a modern grid (32:21) Finding product-market pull through customer discovery (35:56) Raj Tilwa (Focal): personalized heating vs heating entire spaces (44:21) 100+ interviews to find a real painkiller in hospitality (52:10) Nico Pinkowski (Nitricity): decentralized fertilizer production (58:31) How product-market fit can take years Enjoyed this episode? Please leave us a review! Share feedback or suggest future topics and guests at info@mcj.vc.Connect with MCJ:Cody Simms on LinkedInVisit mcj.vcSubscribe to the MCJ Newsletter*Editing and post-production work for this episode was provided by The Podcast Consultant

Fear Chorcaí atá lonnaithe i Munich agus tá grúpa bunaithe aige den teideal ‘Cúpla Focal' le tacaíocht.

We were supposed to record this episode a year ago. But the LA wildfires threatened Travis' home. From platinum records to mixing in headphones across dozens of hotels, Travis and his family wen through a nightmare, but found a way to make it all work.While he lost gear… gear that was imbued with memories and countless hit records… he found new ways to work. What what essential. And kept it all going.We talk about sharing industry wisdom, the value of community, and how mixing in headphones is a slept on art.For 30% off your first year of DistroKid to share your music with the world click ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DistroKid.com/vip/lovemusicmore⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

This month, Jamie Hopkins' new book, “Your Retirement Sketchbook,” co-written by Bonnie Treichel, hits bookstores, and a lot of advisors know Hopkins as a retirement planning expert. Less known is his own personal story, which includes the passing of his father in a job-site accident when he was 8 years old. “This has impacted so many things in my life—my desire to be a dad, a sense I would die early, a fear of heights and a scarcity mindset for years around money,” he writes in the book. In this episode of The Healthy Advisor, host Diana Britton chats with Jamie Hopkins, CEO of Bryn Mawr Trust and co-author of “Your Retirement Sketchbook,” about those fears and how childhood loss shaped his approach to retirement planning and life. He also explains the importance of financial advice access for underserved workers, the career decision that helped him be more present with his children, and why protecting health and relationships should matter as much as building wealth. Jamie discusses: The childhood tragedy that shaped his perspective on money, planning and family priorities Why many workers in trades and small businesses lack access to retirement guidance and financial advice How one comment from his son reshaped his approach to work and travel How scarcity around money can influence lifelong habits and emotional relationships with finances How Jamie invests in his own health Resources: Listen to The Healthy Advisor on Wealth Management Subscribe and listen to The Healthy Advisor on Apple Podcasts Subscribe and listen to The Healthy Advisor on Spotify Book: Your Retirement Sketchbook by Jamie Hopkins and Bonnie Treichel Connect With Jamie Hopkins: LinkedIn: Jamie Hopkins Website: Bryn Mawr Trust jhopkins@bmt.com  Connect with Wealth Management: Wealth Management LinkedIn: Diana Britton diana.britton@informa.com LinkedIn: Informa LinkedIn: Wealth Management About Our Guest: Jamie P. Hopkins is CEO of Bryn Mawr Trust Advisors and CWO of WSFS. A Wall Street Journal best-selling author, educator, and executive speaker, Jamie has previously served on numerous advisory boards around the financial services industry, such as Wing.app, Wealth.com, C2P, IncomeLab, and was a national trustee member of NAIFA. He currently sits on the advisory board of Focal, an AI startup. Jamie is also the founder and president of the 501(c)(3) non-profit, FinServ Foundation, and was recognized as the 2021 RIA Thought Leader of the Year by WealthManagement.com and Top 10 Investopedia 100 Top Financial Advisor for 2023. Jamie has also taught financial planning courses and created course content at Creighton University and American College of Financial Services since 2012.

Do you know how many seizures is too many? Or what drugs to avoid in older epilepsy patients? Credit available for this activity expires: 3/3/27 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/avoiding-common-mistakes-managing-focal-epilepsy-2026a10004kv?ecd=bdc_podcast_libsyn_mscpedu

Interview with Emanuele Cerulli Irelli, MD, PhD, author of Comparative Effectiveness of Brivaracetam, Cenobamate,Lacosamide, and Perampanel in Focal Epilepsy. Hosted by Cynthia E. Armand, MD. Related Content: Comparative Effectiveness of Brivaracetam, Cenobamate, Lacosamide, and Perampanel in Focal Epilepsy

Interview with Emanuele Cerulli Irelli, MD, PhD, author of Comparative Effectiveness of Brivaracetam, Cenobamate,Lacosamide, and Perampanel in Focal Epilepsy. Hosted by Cynthia E. Armand, MD. Related Content: Comparative Effectiveness of Brivaracetam, Cenobamate, Lacosamide, and Perampanel in Focal Epilepsy

Discover why the Focal Bathys remain a top choice for aspiring audiophiles in 2026. From 40mm Aluminum/Magnesium drivers to versatile ANC modes and USB-DAC capabilities, these wireless headphones bridge premium sound and everyday convenience. Check them out here: https://www.samash.com/focal-bathys-wireless-headphones-fbathysbx Sam Ash City: Hicksville Address: 278 Duffy Ave Website: https://www.samash.com/

Whether she's touring with Y La Bamba or scoring live stories for WNYC's Snap Judgment, Geneva Harrison is the kind of artist who breathes life into her work. She's a world-class percussionist and producer, and a total student of how music connects.I loved her takes on the "elasticity" of rhythm. It's steady and unsteady. Like a heartbeat. Human and tied to the environment. The culture. We sat down to talk about her deep dive into Brazilian music, what she's learned from years of touring, and collaborating with everyone from dancers to poets.For 30% off your first year of DistroKid to share your music with the world click ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DistroKid.com/vip/lovemusicmore⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Progress in medicine works best when it brings clarity especially when new prostate cancer treatments promise precision.In this episode, Dr. Stephen Petteruti takes a clear-eyed look at focal therapy and asks the question that matters most: does treating part of the prostate actually change long-term outcomes? He explains the difference between FDA clearance and true cancer effectiveness and how cancer biology challenges the idea of isolated “spot treatment.”The conversation breaks down laser ablation, HIFU, cryotherapy, and TULSA. Dr. Stephen also outlines why careful monitoring and whole-body strategies often protect health and vitality more reliably than localized procedures.Choose care that aligns with long-term health, not short-term promises. Watch the full episode of Focal Therapy for Prostate Cancer: Does It Actually Work?Enjoy the podcast? Subscribe and leave a 5-star review.Dr. Stephen Petteruti is a leading Functional Medicine Physician dedicated to enhancing vitality by addressing health at a cellular level. Combining the best of conventional medicine with advancements in cellular biology, he offers a patient-centered approach through his practice, Intellectual Medicine 120. A seasoned speaker and educator, he has lectured at prestigious conferences like A4M and ACAM, sharing his expertise on anti-aging. His innovative methods include concierge medicine and non-invasive anti-aging treatments, empowering patients to live longer, healthier lives.Website: https://www.intellectualmedicine.com/ Website: https://www.drstephenpetteruti.com/ Men's Vitality Community: https://www.intellectualmedicine.com/membership Consult with Dr. Petteruti: https://www.intellectualmedicine.com/consultation Provider training: https://www.imeduniversity.com/provider-growth-experience YouTube: https://www.youtube.com/@intellectualmedicine Instagram: instagram.com/intellectualmedine Disclaimer:  The content presented in this video reflects the opinions and clinical experience of Dr. Stephen Petteruti and is intended for informational and educational purposes only. It is not medical advice and should not be used as a substitute for professional diagnosis, treatment, or guidance from your personal healthcare provider. Always consult your physician or qualified healthcare professional before making any changes to your health regimen or treatment plan.Produced by https://www.BroadcastYourAuthority.com 

On this show, we cover the Ben Shapiro/Candice/Tucker feud, yet despite all the hate, Israel is leading the world in major areas like defense, technology, and more! Will they hate us for this even more? -with guest: Dr. Mordechai Ben-Menachem, commentator on mid-east and world issues, and author of the book: Muslim Winter https://tinyurl.com/y6g85sec The Tamar Yonah Show 21DEC2025 - PODCAST

Az is AWOL tonight, so FPL Focal steps in to add a touch of class to proceedings. His rank is astronomical at this stage, what has been the secret of his success? Andy will dig into all of that and more. From everyone at FPL BlackBox, if we don't see you before Christmas, we hope you have a great day and may your arrows be green Learn more about your ad choices. Visit podcastchoices.com/adchoices

And tonight… it's a BIG one.

In today's episode, I chat with IFBB Pro Rachel Farganis, a 40-year-old mom of two, full-time professional photographer, who lives in St. Paul, Minnesota. She is a former D1 sprinter and high jumper. After dealing with a string of autoimmune issues and becoming a mom, fitness took a bit of a backseat. But, around 2018, a fellow photographer started their bodybuilding journey and it sparked a flame in her life. She dove in head first in 2019, and hasn't looked back since.   TOPICS COVERED -prepping for the first time during COVID -competing as a mom -finding the right coach -balancing competing and marriage -missing a Pro Card by one spot three different times -winning a national overall with a broken foot -the aftermath of going viral -mindset and the mental difficulties   CONNECT WITH CELESTE: Website: http://www.celestial.fit Instagram: https://www.instagram.com/celestial_fit/ All Links: http://www.celestial.fit/links.html   CONNECT WITH RACHEL:  Instagram: https://www.instagram.com/rachelfarganis/   TIME STAMPS 1:00 introduction 7:07 the aftermath of going viral 14:48 competing with a broken foot 24:10 focuses in the offseason 27:07 competing as a mom 34:40 warning label to competitors 37:02 lessons for her kids 43:33 falling in love with bodybuilding 53:28 first show experience 58:47 finding the right coach 69:04 becoming a photographer 71:44 advice for competitors    CLICK HERE TO SIGN UP FOR THE FREE FOOD RELATIONSHIP COACHING SERIES   CLICK HERE TO SIGN UP FOR THE FREE POST SHOW BLUES COACHING SERIES   LEARN MORE AND APPLY FOR MY 5 WEEK FOOD RELATIONSHIP HEALING & DISCOVERY COACHING PROGRAM   FOR OTHER FREE RESOURCES, LIVE EVENTS, AND WAYS TO WORK WITH CELESTE CLICK HERE

Dr. Katie Krulisky and Dr. Stefano Meletti discuss the incidence and characteristics of postictal central apnea in focal seizures.   Show citation: Meletti S, Burani M, Ballerini A, et al. Persistent Postictal Central Apnea in Focal Seizures: Incidence, Features, and Imaging Findings. Neurology. 2025;105(4):e213856. doi:10.1212/WNL.0000000000213856  

Dr. Katie Krulisky talks with Dr. Stefano Meletti about the incidence and characteristics of postictal central apnea in focal seizures. Read the related article in Neurology®. Disclosures can be found at Neurology.org.