Podcasts about jama neurology

  • 49PODCASTS
  • 166EPISODES
  • 22mAVG DURATION
  • 1MONTHLY NEW EPISODE
  • Jun 18, 2025LATEST

POPULARITY

20172018201920202021202220232024


Best podcasts about jama neurology

Latest podcast episodes about jama neurology

Do you really know?
Should I walk 10000 steps a day?

Do you really know?

Play Episode Listen Later Jun 18, 2025 4:47


Most of us are familiar with the idea that you need to take 10 thousand steps per day to stay healthy but getting to this magic number is not that easy. The 10,000-step target first became popular in Japan in the 1960s. A clockmaker capitalising on people's new interest in fitness following the 1964 Tokyo Olympic Games made a pedometer with a name that, when written in Japanese characters, resembled a walking man and coincidentally translated as “10,000-steps metre.” A study of over 78,000 people in the UK between 2013 and 2015 using wearable trackers was published in the journals JAMA Internal Medicine and JAMA Neurology. Where did we get the number 10 thousand from? Does that mean that we do not need to take 10 steps? So how many steps should I be aiming for per day? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: ⁠Can you eat eggs everyday?⁠ ⁠What is Lucky Girl syndrome, this new method that is all the rage on Tik Tok?⁠ ⁠Which type of wine is best for your health?⁠ A podcast written and realised by Amber Minogue. First broadcast: 19/1/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices

JAMA Medical News: Discussing timely topics in clinical medicine, biomedical sciences, public health, and health policy

Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues tested the ability of an AI model to differentiate between Parkinson disease and other neurodegenerative disorders when paired with MRI. He joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH to discuss. Related Content: A Large Proportion of Parkinson Disease Diagnoses Are Wrong—Here's How AI Could Help Automated Imaging Differentiation for Parkinsonism

JAMA Network
JAMA Neurology : Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome

JAMA Network

Play Episode Listen Later Jun 2, 2025 14:19


Interview with Manuel Comabella, MD, author of Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome. Hosted by Cynthia E. Armand, MD. Related Content: Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome

JAMA Network
JAMA Neurology : Fremanezumab for the Treatment of Migraine and Major Depressive Disorder

JAMA Network

Play Episode Listen Later May 5, 2025 21:13


Interview with Richard B. Lipton, MD, author of Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder. Hosted by Cynthia E. Armand, MD. Related Content: Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder

CBS This Morning - News on the Go
Could Weight Loss Drugs Help Protect Against Dementia? | Florida Gators Star on Winning NCAA National Championship | Idina Menzel Talks Returning to Broadway

CBS This Morning - News on the Go

Play Episode Listen Later Apr 8, 2025 41:41


While large retailers may weather the storm, independent businesses are struggling to absorb rising costs tied to new trade policies. "CBS Mornings" hears from one Los Angeles entrepreneur facing tough choices. Lori Vallow Daybell was in an Arizona court Monday to represent herself in a trial involving the killing of her fourth husband, Charles Vallow, in 2019. In her opening statement, Vallow said the evidence will show it was self defense, but prosecutors argued she conspired with her brother to kill Vallow, who had filed for divorce, to collect a $1 million life insurance policy. Two new studies in JAMA Neurology show some diabetes and popular weight loss drugs could help to protect against dementia. CBS News medical contributor Dr. Celine Gounder joins "CBS Mornings" to explain what researchers found. The Florida Gators won their first NCAA basketball title since 2007. Will Richard, who hit four three-pointers in the first half, speaks about the big win, what he'll remember from this season and the next steps in his career. Deja Kelly has turned her platform into a personal brand, but she says having the right support system — from a financial advisor to her "momager" — is key to staying grounded in the new NIL economy. With just days to go before liftoff, Gayle King gets a surprise sendoff on "CBS Mornings" from friends and famous faces including Tom Hanks, William Shatner, Bill Nye and Megan Rapinoe. Nearly a decade since her last Broadway role, Idina Menzel is back, this time climbing through midair as a grieving mother who finds healing and hope in California's redwood forest. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

JAMA Network
JAMA Neurology : Optimal Delay Time to Initiate Anticoagulation After AF-Associated Ischemic Stroke

JAMA Network

Play Episode Listen Later Mar 31, 2025 16:54


Interview with Steven J. Warach, MD, PhD, author of Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation: A Pragmatic, Response-Adaptive Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation

JAMA Network
JAMA Neurology : Location and Timing of Recurrent, Nontraumatic Intracerebral Hemorrhage

JAMA Network

Play Episode Listen Later Mar 3, 2025 15:57


Interview with David J. Seiffge, MD, author of Location and Timing of Recurrent, Nontraumatic Intracerebral Hemorrhage. Hosted by Cynthia E. Armand, MD. Related Content: Location and Timing of Recurrent, Nontraumatic Intracerebral Hemorrhage

The Parkinson's Experience podcast
109 Connect and Prepare for the Heat

The Parkinson's Experience podcast

Play Episode Listen Later Feb 13, 2025 34:40


As the earth continues to get warmer and we see record high temperatures across the globe, scientists tell us that this pattern is going to continue and be more common. Higher temperatures, more frequently has led to more heat strokes and other conditions when people aren't prepared for this situation.  Additionally, people with neurodegenerative diseases like Parkinson's are at greater risk for heat related complications, A recent article published in JAMA Neurology, describes the issue, what to look for, and how we, as individuals and community, can help to prevent people from heat related complications. It was co-written by my guest today, Indu Subramanian, MD, a neurologist and movement disorders researcher at the University of California, Los Angeles (UCLA), and Al Saad, MD, a neurologist with expertise in climate change at the University of Colorado. With summer around the corner, this is a great time to prepare for the heat and work with your healthcare team on a plan to prevent any heat related issues. We as a community need to look out for our neighbors, friends and family. Our neighbors   may be isolated or scared if they have Parkinson's diseasae or are older. As a community, we should come together to identify people who may need our help during a difficult situation such as heatwaves and higher temperatures, especially in areas in the world where they are not prepared to assist. We should keep in touch, check in, offer some water.   Learn all about how to prepare, provent, find help as well as recognizing the symptoms of heatstroke on this episode of the Parkinson's Experience. https://www.parkinsonsecrets.com/  https://parkinsonsnewstoday.com/news/heat-intolerance-rising-parkinsons-risk-climbing-temperatures/ https://www.uclahealth.org/providers/indu-subramanian https://www.dbsandme.com/en.html  

JAMA Network
JAMA Neurology : Cardiovascular Safety of Anti-CGRP Monoclonal Antibodies in Older Adults or Adults With Disability With Migraine

JAMA Network

Play Episode Listen Later Jan 6, 2025 18:09


Interview with Wei-Hsuan Lo-Ciganic, PhD, author of Cardiovascular Safety of Anti-CGRP Monoclonal Antibodies in Older Adults or Adults With Disability With Migraine. Hosted by Cynthia E. Armand, MD. Related Content: Cardiovascular Safety of Anti-CGRP Monoclonal Antibodies in Older Adults or Adults With Disability With Migraine

Do you really know?
Should I walk 10000 steps a day?

Do you really know?

Play Episode Listen Later Dec 18, 2024 4:17


Most of us are familiar with the idea that you need to take 10 thousand steps per day to stay healthy but getting to this magic number is not that easy. The 10,000-step target first became popular in Japan in the 1960s. A clockmaker capitalising on people's new interest in fitness following the 1964 Tokyo Olympic Games made a pedometer with a name that, when written in Japanese characters, resembled a walking man and coincidentally translated as “10,000-steps metre.” A study of over 78,000 people in the UK between 2013 and 2015 using wearable trackers was published in the journals JAMA Internal Medicine and JAMA Neurology. Where did we get the number 10 thousand from? Does that mean that we do not need to take 10 steps? So how many steps should I be aiming for per day? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Can you eat eggs everyday? What is Lucky Girl syndrome, this new method that is all the rage on Tik Tok? Which type of wine is best for your health? A podcast written and realised by Amber Minogue. First broadcast: 19/1/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices

JAMA Network
JAMA Neurology : β-Blocker Use and Delayed Onset and Progression of Huntington Disease

JAMA Network

Play Episode Listen Later Dec 2, 2024 18:33


Interview with Jordan L. Schultz, PharmD, author of β-Blocker Use and Delayed Onset and Progression of Huntington Disease. Hosted by Cynthia E. Armand, MD. Related Content: β-Blocker Use and Delayed Onset and Progression of Huntington Disease

JAMA Network
JAMA Neurology : Alzheimer Disease as a Clinical-Biological Construct

JAMA Network

Play Episode Listen Later Nov 1, 2024 22:01


Interview with Giovanni B. Frisoni, MD, author of Alzheimer Disease as a Clinical-Biological Construct—An International Working Group Recommendation. Hosted by Cynthia E. Armand, MD. Related Content: Alzheimer Disease as a Clinical-Biological Construct—An International Working Group Recommendation

Sharp Waves: ILAE's epilepsy podcast
Practice guideline on outcomes after in utero exposure to anti-seizure medications: Dr. Alison Pack

Sharp Waves: ILAE's epilepsy podcast

Play Episode Listen Later Oct 28, 2024 23:41 Transcription Available


A recent practice guideline provides updated evidence-based conclusions and recommendations regarding in utero effects of anti-seizure medications and folic acid supplementation on the prevalence of major congenital malformations, adverse perinatal outcomes, and neurodevelopmental outcomes. Dr. Parthvi Ravat interviewed Dr. Alison Pack about the guideline, which was produced by the American Academy of Neurology, American Epilepsy Society, and Society for Maternal-Fetal Medicine.Review the practice guideline: Teratogenesis, perinatal, and neurodevelopmental outcomes after in utero exposure to antiseizure medication (Neurology, May 2024)Other studies mentioned in the episode: Risk of major congenital malformations and exposure to antiseizure medication monotherapy (JAMA Neurology, March 2024) Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.Let us know how we're doing: podcast@ilae.org.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, X (Twitter), Instagram, and LinkedIn.

JAMA Network
JAMA Neurology : Perceived CTE in Former Professional Football Players

JAMA Network

Play Episode Listen Later Sep 23, 2024 17:09


Interview with Rachel Grashow, PhD, MS, and Aaron L. Baggish, MD, authors of Perceived Chronic Traumatic Encephalopathy and Suicidality in Former Professional Football Players. Hosted by Cynthia E. Armand, MD. In the US, you can call, text, or chat 988, the Suicide and Crisis Lifeline. Related Content: Perceived Chronic Traumatic Encephalopathy and Suicidality in Former Professional Football Players

Neurology® Podcast
Blood Biomarkers to Detect Alzheimer Disease

Neurology® Podcast

Play Episode Listen Later Aug 29, 2024 22:21


Dr. Gregg Day talks with Dr. Sebastian Palmqvist about the use of blood biomarkers to streamline the diagnostic workup and treatment of Alzheimer disease. Read the related article in JAMA Neurology. Disclosures can be found at Neurology.org.

JAMA Network
JAMA Neurology : Localized Nicardipine Release Implants for Prevention of Vasospasm

JAMA Network

Play Episode Listen Later Aug 19, 2024 15:20


Interview with Peter Vajkoczy, MD, author of Localized Nicardipine Release Implants for Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage: A Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Localized Nicardipine Release Implants for Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage

Neurology® Podcast
Tapping the Brakes on New Parkinson Disease Biological Staging

Neurology® Podcast

Play Episode Listen Later Jul 29, 2024 17:45


Dr. Matthew Barrett talks with Dr. Michael S. Okun about the caution and deliberation needed in understanding Parkinson disease biomarkers. Read the related viewpoint piece in JAMA Neurology. Disclosures can be found at Neurology.org.

JAMA Network
JAMA Neurology : Direct-Acting OACs and Antiseizure Medications for AF and Epilepsy and Risk of Thromboembolic Events

JAMA Network

Play Episode Listen Later Jul 8, 2024 19:32


Interview with Allison W. Willis, MD, MS, author of Direct-Acting Oral Anticoagulants and Antiseizure Medications for Atrial Fibrillation and Epilepsy and Risk of Thromboembolic Events. Hosted by Cynthia E. Armand, MD. Related Content: Direct-Acting Oral Anticoagulants and Antiseizure Medications for Atrial Fibrillation and Epilepsy and Risk of Thromboembolic Events

Do you really know?
Should I walk 10000 steps a day?

Do you really know?

Play Episode Listen Later May 30, 2024 4:17


Most of us are familiar with the idea that you need to take 10 thousand steps per day to stay healthy but getting to this magic number is not that easy. The 10,000-step target first became popular in Japan in the 1960s. A clockmaker capitalising on people's new interest in fitness following the 1964 Tokyo Olympic Games made a pedometer with a name that, when written in Japanese characters, resembled a walking man and coincidentally translated as “10,000-steps metre.” A study of over 78,000 people in the UK between 2013 and 2015 using wearable trackers was published in the journals JAMA Internal Medicine and JAMA Neurology. Where did we get the number 10 thousand from? Does that mean that we do not need to take 10 steps? So how many steps should I be aiming for per day? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Can you eat eggs everyday? What is Lucky Girl syndrome, this new method that is all the rage on Tik Tok? Which type of wine is best for your health? A podcast written and realised by Amber Minogue. First broadcast: 19/01/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices

JAMA Network
JAMA Neurology : Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation

JAMA Network

Play Episode Listen Later May 28, 2024 18:13


Interview with Urs Fischer, MD, MSc, author of Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation: Post Hoc Analysis of the ELAN Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation

JAMA Network
JAMA Neurology : Association of New-Onset Seizures With SARS-CoV-2 Vaccines

JAMA Network

Play Episode Listen Later Apr 29, 2024 16:43


Interview with Churl-Su Kwon, MD, MPH, author of Association of New-Onset Seizures With SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Hosted by Cynthia E. Armand, MD. Related Content: Association of New-Onset Seizures With SARS-CoV-2 Vaccines

interview vaccines md mph sars cov seizures onset meta analysis jama neurology randomized clinical trials related content association
JAMA Network
JAMA Neurology : High-Efficacy Therapy Discontinuation vs Continuation in Patients 50 Years and Older With Nonactive MS

JAMA Network

Play Episode Listen Later Mar 25, 2024 14:08


Interview with Anne Kerbrat, MD, PhD, author of High-Efficacy Therapy Discontinuation vs Continuation in Patients 50 Years and Older With Nonactive MS. Hosted by Cynthia E. Armand, MD. Related Content: High-Efficacy Therapy Discontinuation vs Continuation in Patients 50 Years and Older With Nonactive MS

Neurology® Podcast
The Perils and Pitfalls of Global Engagement

Neurology® Podcast

Play Episode Listen Later Mar 7, 2024 23:09


Dr. Deanna Saylor talks with Drs. Gretchen Birbeck and Melody Asukile about ways to improve global collaboration among neurologists. Read the related article in JAMA Neurology. Disclosures can be found at Neurology.org.

Medmastery's Cardiology Digest
#9: A primary mechanism behind decompression illness, cognitive repercussions of a myocardial infarction, and high-sensitivity cardiac troponin I (hs-cTnI) for risk-stratification of coronary artery disease

Medmastery's Cardiology Digest

Play Episode Listen Later Feb 27, 2024 10:30


Our latest episode dissects three groundbreaking studies that are reshaping our understanding of the heart and its intricate connections to the body and mind.   STUDY #1: First, we explore the potential of high-sensitivity cardiac troponin I (hs-cTnI) in risk-stratifying patients with known coronary artery disease. While current guidelines don't yet recommend these tests, could there be untapped value in using troponin concentration as a preventive treatment guide? Join us as we explore the intriguing possibilities and implications presented in this study from the Journal of the American College of Cardiology. Wereski, R, Adamson, P, Daud, NSS, et al. 2023. High-sensitivity cardiac troponin for risk assessment in patients with chronic coronary artery disease. J Am Coll Cardiol. 6: 473–485. (https://doi.org/10.1016/j.jacc.2023.05.046)   STUDY #2: Next, we shift our focus to the brain-heart connection. Ever wondered about the cognitive repercussions of a myocardial infarction (MI)? This study from JAMA Neurology sheds light on the potential cognitive consequences of an MI.  Johansen, MC, Ye, W, Gross, A, et al. 2023. Association between acute myocardial infarction and cognition. JAMA Neurol. 7: 723–731. (https://doi.org/10.1001/jamaneurol.2023.1331)   STUDY #3: Third, we dive deep (pun intended!) into decompression illness. Certain divers might want to reconsider their next dive because a recent Annals of Internal Medicine study suggests a primary mechanism behind decompression illness that could change the way we perceive diving risks. What are the implications for those passionate about the deep blue? Lee, H-J, Lim, DS, Lee, J, et al. 2023. Decompression illness in divers with or without patent foramen ovale: A cohort study. Ann Intern Med. 7: 934–939. (https://doi.org/10.7326/M23-0260)   Don't miss out on these captivating discussions. Listen in to stay at the forefront of cardiology insights and to satiate your curiosity about these studies' findings. We promise, it's a heartbeat away from being your favorite episode yet! For show notes, visit us at https://www.medmastery.com/podcasts/cardiology-podcast.

JAMA Network
JAMA Neurology : Posttraumatic Epilepsy and Dementia Risk

JAMA Network

Play Episode Listen Later Feb 26, 2024 13:01


Interview with Andrea L. C. Schneider, MD, PhD, author of Posttraumatic Epilepsy and Dementia Risk. Hosted by Cynthia E. Armand, MD. Related Content: Posttraumatic Epilepsy and Dementia Risk

JAMA Network
JAMA Neurology : Risk of Stroke and Myocardial Infarction Among Initiators of Triptans

JAMA Network

Play Episode Listen Later Feb 5, 2024 10:52


Interview with Jesper Hallas, MD, DMSc, author of Risk of Stroke and Myocardial Infarction Among Initiators of Triptans. Hosted by Cynthia E. Armand, MD. Related Content: Risk of Stroke and Myocardial Infarction Among Initiators of Triptans

Espacio Vital
¿Existe una nueva forma de diagnosticar el Alzheimer?

Espacio Vital

Play Episode Listen Later Jan 31, 2024 6:53


Un análisis de sangre permite diagnosticar la enfermedad del Alzheimer con una precisión de alrededor del 95%, según los resultados de un estudio publicado por la revista JAMA Neurology, en el que han participado investigadores del Hospital de Sant Pau (Barcelona).

JAMA Network
JAMA Neurology : Risk Factors for Young-Onset Dementia in the UK Biobank

JAMA Network

Play Episode Listen Later Dec 26, 2023 14:35


Interview with Stevie Hendriks, PhD, author of Risk Factors for Young-Onset Dementia in the UK Biobank. Hosted by Cynthia E. Armand, MD. Related Content: Risk Factors for Young-Onset Dementia in the UK Biobank

JAMA Network
JAMA Neurology : Endovascular Therapy Outcomes by ASPECTS and Infarct Core Volume in Patients With Large Infarct

JAMA Network

Play Episode Listen Later Nov 27, 2023 14:16


Interview with Zhongrong Miao, MD, author of Alberta Stroke Program Early Computed Tomography Score, Infarct Core Volume, and Endovascular Therapy Outcomes in Patients With Large Infarct: A Secondary Analysis of the ANGEL-ASPECT Trial. Hosted by Cynthia E. Armand, MD. Read Transcript Related Content: Alberta Stroke Program Early Computed Tomography Score, Infarct Core Volume, and Endovascular Therapy Outcomes in Patients With Large Infarct

JAMA Network
JAMA Neurology : Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis

JAMA Network

Play Episode Listen Later Nov 6, 2023 19:03


Interview with Ari J. Green, MD, author of Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis. Hosted by Cynthia E. Armand, MD. Related Content: Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis

JAMA Network
JAMA Neurology : Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease

JAMA Network

Play Episode Listen Later Oct 30, 2023 17:27


Interview with Richard A. Bernstein, MD, PhD, author of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: 3-Year Results From the STROKE AF Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease

Neurology® Podcast
Artificial Intelligence Interpretation of EEG

Neurology® Podcast

Play Episode Listen Later Oct 5, 2023 11:40


Dr. Halley Alexander talks with Dr. Sándor Beniczky about the use of artificial intelligence to accurately interpret routine clinical electroencephalograms. Read the relate article in JAMA Neurology. Visit NPUb.org/Podcast for associated article links.

JAMA Network
JAMA Neurology : Neuropathologic and Clinical Findings in Athletes With Repetitive Head Impacts

JAMA Network

Play Episode Listen Later Aug 28, 2023 16:39


Interview with Ann C. McKee, MD, author of Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts. Hosted by Cynthia E. Armand, MD. Related Content: Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts

Neurology® Podcast
Using Brain Network Mapping in Lesion-Related Epilepsy

Neurology® Podcast

Play Episode Listen Later Aug 21, 2023 9:18


Dr. Jason Crowell talks with Dr. Frederic Schaper about legion-related epilepsy mapping to specific brain networks.  Read the related article in JAMA Neurology.  Visit NPUb.org/Podcast for additional podcasts and associated article links.

Many Minds
Matrescence and the brain

Many Minds

Play Episode Listen Later Jul 26, 2023 78:58


Scientists who study the mind and brain have always been drawn to periods of intense change—to those life stages marked by rapid transformation. Infancy is one of those periods, of course. Adolescence is another. But there's a less-discussed time of life when our brains and minds have to reconfigure: the window surrounding when we become parents.  My guests today are Dr. Winnie Orchard and Dr. Jodi Pawluski. Winnie is a cognitive neuroscientist and postdoctoral scholar at the Yale Child Study Center. Jodi is a neuroscientist, author, and podcaster affiliated with the University of Rennes in France. Both are experts in the neural and cognitive changes that surround pregnancy, motherhood, and parenthood more generally.  Here, we talk about the idea of "matrescence" as a distinctive developmental stage. We discuss the research around memory loss in early motherhood, as well as findings that certain brain areas get fine-tuned during this period. We talk about postpartum anxiety, depression, and psychosis, and what may be causing them. We consider the finding that having children—and, in fact, having more children—seems to confer a protective effect on the aging brain. Throughout we talk about which of these changes also occur in fathers and other non-birthing parents. And we consider the difficulty of scientifically studying a period of life—parenthood—that is not only rife with social and psychological changes, but also fraught with expectations and narratives. Alright friends, I hope you enjoy this one. As you'll hear, this research area is very much still in its infancy. There are definitely some provocative findings. But maybe more exciting are all the questions that remain. Without further ado, here's my chat with Dr. Winnie Orchard and Dr. Jodi Pawluski. Enjoy!   A transcript of this episode will be available soon.   Notes and links 2:45 – For more on the relationship between adolescence and “matrescence,” see this recent review paper by Winnie and colleagues in Trends in Cognitive Sciences. 6:00 – For discussions surrounding the idea of “mommy brain,” see Jodi's podcast, ‘Mommy Brain Revisited.' See also this recent editorial by Jodi and colleagues in JAMA Neurology.  17:00 – A recent meta-analysis on cognitive impairment during pregnancy.  25:00 – A study by Winnie and colleagues showing subjective—but not objective—memory deficits in mothers one year after giving birth.   26:45 – An influential study showing structural changes in the brain following pregnancy. The same study also found that some of these changes correlated with measures of maternal attachment. 28:00 – A recent review article by Jodi and colleagues on the idea of neural fine-tuning in early motherhood.   41:45 – A recent review paper by Jodi and colleagues about the neural underpinnings of postpartum depression and anxiety.  44:00 – A review paper about postpartum psychosis.  51:00 – A study on the prevalence of postpartum depression across cultures.  58:00 – A 2014 review of research on mother-child synchrony. 1:00:00 – A recent study by Winnie and colleagues looking at how having children affects later life brain function. Another study by Winnie and colleagues on the same topic.  1:13:00 – Several studies have documented general changes in “Big 5” personality factors as people age. A study examining this in both American and Japanese participants is here. 1:18:00 – Since we recorded this interview, the publication date for the English version of Jodi's book has been scheduled. It comes out in September 2023—more info here.   Recommendations  Dr. Orchard recommends: Baby Brain, Sarah McKay Mother Brain, Chelsea Conaboy   Dr. Pawluski recommends: Matrescence, by Lucy Jones After the Storm, by Emma Jane Unsworth   Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the Templeton World Charity Foundation to UCLA. It is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Our transcripts are created by Sarah Dopierala. Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here! We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com.  For updates about the show, visit our website or follow us on Twitter: @ManyMindsPod.

JAMA Network
JAMA Neurology : Dementia Risk and Disadvantaged Neighborhoods

JAMA Network

Play Episode Listen Later Jul 19, 2023 17:08


Interview with Kristine Yaffe, MD, author of Dementia Risk and Disadvantaged Neighborhoods. Hosted by Cynthia E. Armand, MD. Related Content: Dementia Risk and Disadvantaged Neighborhoods

ANA Investigates
ANA Investigates Parkinsons and Environmental Toxins

ANA Investigates

Play Episode Listen Later Jun 27, 2023 18:26


A recent study in JAMA Neurology found an association between contaminated water at a military base in the 1970s-80s and the risk of Parkinson's disease in military service members. What do we know about Parkinson's and environmental toxins? Series 4, Episode 9 Featuring: Guest: Dr. Ray Dorsey, University of Rochester Interviewer: Dr. Sara Stern-Nezer, UC Irvine Disclosures: This episode does not award CME credit.

JAMA Network
JAMA Neurology : Automated Interpretation of Clinical Electroencephalograms Using Artificial Intelligence

JAMA Network

Play Episode Listen Later Jun 20, 2023 13:47


Interview with Sándor Beniczky, MD, PhD, author of Automated Interpretation of Clinical Electroencephalograms Using Artificial Intelligence. Hosted by Cynthia Armand, MD. Related Content: Automated Interpretation of Clinical Electroencephalograms Using Artificial Intelligence

JAMA Network
JAMA Neurology : Risk of Parkinson Disease Among Camp Lejeune Veterans

JAMA Network

Play Episode Listen Later May 15, 2023 21:24


Interview with Samuel M. Goldman, MD, MPH, author of Risk of Parkinson Disease Among Service Members at Marine Corps Base Camp Lejeune. Hosted by Cynthia E. Armand, MD. Related Content: Risk of Parkinson Disease Among Service Members at Marine Corps Base Camp Lejeune Large Study Links Industrial Solvent in Drinking Water to Parkinson Disease Risk in Camp Lejeune Veterans

JAMA Network
JAMA Neurology : Prenatal Exposure to Antiseizure Medication and Psychiatric Disorders

JAMA Network

Play Episode Listen Later Apr 17, 2023 17:21


Interview with Julie Werenberg Dreier, PhD, author of Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders. Hosted by Cynthia E. Armand, MD. Related Content: Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders

JAMA Network
JAMA Neurology : Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors

JAMA Network

Play Episode Listen Later Mar 27, 2023 19:36


Interview with Xin You Tai, MD, author of Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors. Hosted by Cynthia E. Armand, MD. Related Content: Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors

Neurology® Podcast
Modern Neurology Training Is Failing Outpatients

Neurology® Podcast

Play Episode Listen Later Mar 16, 2023 13:53


Read the related article in JAMA Neurology. 

JAMA Network
JAMA Neurology : Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke

JAMA Network

Play Episode Listen Later Feb 23, 2023 17:09


Interview with Pierce Boyne, PT, DPT, PhD, NCS, author of Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke: A Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke

Neurology® Podcast
Estimating the Prevalence of Dementia and Mild Cognitive Impairment in the United States

Neurology® Podcast

Play Episode Listen Later Feb 2, 2023 18:39


Dr. Roy Hamilton talks with Dr. Kenneth Langa, about the prevalence of dementia and mild cognitive impairment in the US. Read the full article in JAMA Neurology. This episode is brought to you by Mass General Brigham Department of Neurology, please visit us at www.massgeneralbrigham.org.

Neurology® Podcast
Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants

Neurology® Podcast

Play Episode Listen Later Jan 26, 2023 23:09


Dr. Dan Ackerman talks with Dr. David Seiffge, about the use of oral anticoagulants on ischemic stroke. Read the full article in JAMA Neurology. This episode is brought to you by Mass General Brigham Department of Neurology, please visit us at www.massgeneralbrigham.org.

Neurology® Podcast
Autoimmune Encephalitis Misdiagnosis in Adults

Neurology® Podcast

Play Episode Listen Later Dec 22, 2022 13:24


Dr. Justin Abbatemacro talks with Dr. Eoin Flanagan, about the misdiagnosis of autoimmune encephalitis. Read the full article discussed in this interview in JAMA Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Neurology® Podcast
Efficacy and Safety of Rituximab for New-Onset Generalized Myasthenia Gravis

Neurology® Podcast

Play Episode Listen Later Dec 8, 2022 21:22


Dr. Gordon Smith talks with Dr. Fredrik Piehl, about the use of rituximab for new-onset generalized myasthenia gravis. Read the full article on JAMA Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Neurology® Podcast
Risk of Suicide After Dementia Diagnosis

Neurology® Podcast

Play Episode Listen Later Dec 1, 2022 16:23


Dr. Shuvro Roy talks with Dr. Charles Marshall, about the increased risk of suicide following a dementia diagnosis. Read the full article discussed in this interview in JAMA Neurology. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

The Gary Null Show
The Gary Null Show - 09.23.22

The Gary Null Show

Play Episode Listen Later Sep 26, 2022 53:43


Omega-3 and Omega-6 supplement improves reading for children University of Gothenburg, Sweden - September 14, 2022   Supplement of omega-3 and omega-6 fatty acids may improve reading skills of mainstream schoolchildren, according to a new study from Sahlgrenska Academy, at the University of Gothenburg, Sweden. Children with attention problems, in particular, may be helped in their reading with the addition of these fatty acids.   The study included 154 schoolchildren from western Sweden in grade 3, between nine and ten years old. The children took a computer-based test (known as the Logos test) that measured their reading skills in a variety of ways, including reading speed, ability to read nonsense words and vocabulary.   The children were randomly assigned to receive either capsules with omega-3 and omega-6, or identical capsules that contained a placebo (palm oil) for 3 months. The children, parents and researchers did not learn until the study was completed which children had received fatty acids and which had received the placebo. After three months, all children received real omega-3/6 capsules for the final three months of the study.   "Even after three months, we could see that the children's reading skills improved with the addition of fatty acids, compared with those who received the placebo. This was particularly evident in the ability to read a nonsense word aloud and pronounce it correctly (phonologic decoding), and the ability to read a series of letters quickly (visual analysis time)," says Mats Johnson, who is chief physician and researcher at the Gillberg Neuropsychiatry Centre at Sahlgrenska Academy, University of Gothenburg.   No children diagnosed with ADHD were included in the study, but with the help of the children's parents, the researchers could identify children who had milder attention problems. These children attained even greater improvements in several tests, including faster reading already after three months of receiving fatty acid supplements.     Mango could help maintain gut bacteria at risk from high-fat diets Oklahoma State University, SEPTEMBER 21, 2022 Mango consumption could help prevent the loss of beneficial gut bacteria caused by a high fat diet, according to research on mice. The findings, published in the Journal of Nutrition , appears to reveal for the first time the positive impact of mango on gut microbiota. In the study, 60 male mice were assigned to one of four dietary treatment groups for 12 weeks - control (with 10% of calories from fat), high fat (with 60% calories from fat), or high fat with 1% or 10% mango. All high-fat diets had similar macronutrient, calcium, phosphorus, and fiber content. “We investigated the effects of freeze-dried mango pulp combined with an high-fat diet on the cecal microbial population and its relation to body composition, lipids, glucose parameters, short-chain fatty acid (SCFA) production, and gut inflammatory markers in a mouse model of diet-induced obesity,” the study reports. The high-fat dietary treatment with 10% mango (equivalent to 1½ cups of fresh mango pieces) was found to be the most effective in preventing the loss of beneficial bacteria from a high-fat diet without decreasing body weight or fat accumulation. Specifically, mango supplementation regulated gut bacteria in favor of Bifidobacteria and Akkermansia and enhanced short-chain fatty acid (SFCA) production. SCFAs have been shown to possess a wide range of beneficial effects, such as anti-inflammatory properties. Yoga improves arthritis symptoms and mood, study finds  Johns Hopkins School of Medicine,  September 15, 2022 A randomized trial of people with two common forms of arthritis has found that yoga can be safe and effective for people with arthritis. Johns Hopkins researchers report that 8 weeks of yoga classes improved the physical and mental wellbeing of people with two common forms of arthritis, knee osteoarthritis and rheumatoid arthritis. The study is believed to be the largest randomized trial so far to examine the effect of yoga on physical and psychological health and quality of life among people with arthritis. The study recruited 75 people with either knee osteoarthritis or rheumatoid arthritis. Participants were randomly assigned to either a wait list or eight weeks of twice-weekly yoga classes, plus a weekly practice session at home. Participants' physical and mental wellbeing was assessed before and after the yoga session by researchers who did not know which group the participants had been assigned to. Compared with the control group, those doing yoga reported a 20% improvement in pain, energy levels, mood and physical function, including their ability to complete physical tasks at work and home. Walking speed also improved to a smaller extent, though there was little difference between the groups in tests of balance and upper body strength. Improvements in those who completed yoga was still apparent nine months later.   Stevia Kills Lyme Disease Pathogen Better Than Antibiotics (Preclinical Study) University of New Haven, September 21, 2022 A promising new preclinical study has revealed that whole stevia leaf extract possesses exceptional antibiotic activity against the exceedingly difficult to treat pathogen Borrelia Burgdorferi known to cause Lyme disease. The study found, "Stevia whole leaf extract, as an individual agent, was effective against all known morphological forms of B. burgdorferi." At present, the CDC acknowledges that at least 300,000 are infected with Lyme disease, annually, with the conventional standard of care relying on antibiotics that are not only toxic but increasingly coming under scrutiny for addressing only surface aspects of the infection, often leaving antibiotic-resistance Lyme disease deep within the system to continue to cause harm.  The new study was published in the European Journal of Microbiology & Immunology and conducted by researchers from the Department of Biology and Environmental Science, University of New Haven, West Haven, CT. The researchers directly compared an alcohol extract of a whole stevia leaf product commonly found on the U.S. retail market to conventional antibiotics, and assessed their respective abilities to kill the various forms of Borrelia burgdorferi, including so called "persister" forms. The researchers explored Stevia's potential effectiveness against B. burgdorferi cultures, comparing it to three common antibiotics sometimes used to treat Lyme's disease: doxycycline, cefoperazone, daptomycin, as well as their combination. The study results were summarized as follows:     Our results demonstrated that Stevia had significant effect in eliminating B. burgdorferi spirochetes and persisters. Sub-culture experiments with Stevia and antibiotics treated cells were established for 7 and 14 days yielding, no and 10% viable cells, respectively compared to the above-mentioned antibiotics and antibiotic combination. When Stevia and the three antibiotics were tested against attached biofilms, Stevia significantly reduced B. burgdorferi forms. Results from this study suggest that a natural product such as Stevia leaf extract could be considered as an effective agent against B. burgdorferi." Notably, the study found that the most antibiotic resistant form of B. burgdorferi, the biofilm form, actually increased in mass when individual antibiotics were administered. Stevia, on the other hand, reduced the biofilm mass on both tested surfaces (plastic and collagen) by about 40%.     Green soy extract could prevent cognitive dysfunction: Mouse data University of Shizuoka (Japan), September 19, 2022   Intake of green soybean extract could help reverse cognitive dysfunction and its associated accumulation of beta-amyloid proteins in the brain, say researchers.   The accumulation of beta-amyloid proteins has long been linked to the development of brain stunting conditions including Alzheimer's disease and other forms of dementia.    Writing in the Journal of Functional Foods, the team revealed that brain functions were ‘significantly better-preserved' in aged mice fed green soybean than age-matched control mice with or without yellow soybean feeding.   An increased expression of lipocalin-type prostaglandin D2 synthase (Ptgds) and a significant reduction in the amyloid precursor protein Aplp1 was reported by the team, led by Keiko Unno from the University of Shizuoka in Japan.   “Furthermore, the amount of beta-amyloid 40 and 42 was reduced in the insoluble fraction of cerebral cortex,” the team noted.   In the current study, the isoflavones found to be present in soybean extracts were mostly the glycosides genstin and daidzin. Furthermore, the contents of saponin and carotene in green soybean were found to be slightly higher in the green than in yellow, however the contents of other components were not different between green and yellow soybeans.       JAMA study links low vitamin D levels to ‘profound' and ‘rapid' cognitive decline Rutgers University & University of California Davis, September 15, 2022 Vitamin D deficiency and insufficiency may have “substantial” accelerating effects on cognitive decline in the elderly, says a new study from UC Davis and Rutgers University. Low levels of the sunshine vitamin were associated with a three times faster rate of cognitive decline than those with adequate vitamin D levels, according to findings published in JAMA Neurology . The low vitamin D levels were associated with impaired performance, particularly in domains such as memory loss that are associated with Alzheimer's disease and dementia, added the researchers. The researchers said their findings amplify the importance of identifying vitamin D insufficiency among the elderly, particularly high-risk groups such as African-Americans and Hispanics, who are less able to absorb the nutrient from its most plentiful source: sunshine. Among those groups and other darker-skinned individuals, low vitamin D should be considered a risk factor for dementia, they added. Dr Miller and his co-workers analyzed data from 382 racially and ethnically diverse men and women (mean age of 76) in Northern California participating in longitudinal research at the Alzheimer's Disease Center in Sacramento. Of the participants, 41% were white, 30% were African American, 25% were Hispanics, and 4% were from other racial/ethnic groups. The participants were either cognitively normal, or had mild cognitive impairment or dementia. Baseline data showed that 26% of the participants were vitamin D deficient, while 35% were insufficient. Among Caucasians, 54% had low vitamin D, compared with 70% of African-Americans and Hispanics. The rate of cognitive decline was found to be two-to-three times faster in the vitamin D deficient people over five years of study, compared to people with adequate serum vitamin D levels. In other words, it took only two years for the deficient individuals to decline as much as those with adequate vitamin D declined during the five-year follow-up period.

The Gary Null Show
The Gary Null Show - 09.15.22

The Gary Null Show

Play Episode Listen Later Sep 15, 2022 54:27


Videos :   ELDERLY SUICIDE – This is Agenda 21 – MUST SEE! 2022 Fauci, meet 2004 Fauci. FACT CHECK: it did not go well for 2022 Fauci.  (1:23) Sam Bailey & Jessic Rose Part 1 (22:33) Gary Null Speaking Out at the NYS Assembly Hearing  (25:00)   Higher omega-3 levels linked to better sleep University of British Columbia, September 14 2022.  Having higher blood concentrations of the omega-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) was found to be associated with a reduction in excessive sleep in an analysis reported in 2022 in the American Journal of Clinical Nutrition. Sleep duration of over 9 hours per night has been correlated with an increased risk of cardiovascular disease and premature mortality from all causes. The analysis included 21,653 participants in 12 studies for whom information was available concerning sleep duration and/or difficulty falling asleep and blood levels of the omega-3 fatty acids EPA, DHA, ALA and, when available, DPA, and the omega-6 fatty acids AA and LA. When men and women whose fatty acid levels were among the lowest 20% of participants were compared to those whose levels were among the top 20%, individuals whose DHA intake was highest had a 22% lower risk of excessive sleep. Being among those who had the highest intake of EPA plus DHA and DPA was associated with a 24% lower risk. The authors noted that DHA's role in regulating melatonin production helps regulate sleep.  Twice-daily nasal irrigation reduces COVID-related illness, death Medical College of Georgia at Augusta University, September 13, 2022 Starting twice daily flushing of the mucus-lined nasal cavity with a mild saline solution soon after testing positive for COVID-19 can significantly reduce hospitalization and death, investigators report. They say the technique that can be used at home by mixing a half teaspoon each of salt and baking soda in a cup of boiled or distilled water then putting it into a sinus rinse bottle is a safe, effective and inexpensive way to reduce the risk of severe illness and death from coronavirus infection that could have a vital public health impact.  “By giving extra hydration to your sinuses, it makes them function better. “We found an 8.5-fold reduction in hospitalizations and no fatalities compared to our controls,” says senior author Dr. Richard Schwartz, chair of the MCG Department of Emergency Medicine. “Both of those are pretty significant endpoints.” The study appears to be the largest, prospective clinical trial of its kind and the older, high-risk population they studied—many of whom had preexisting conditions like obesity and hypertension—may benefit most from the easy, inexpensive practice, the investigators say. They found that less than 1.3% of the 79 study subjects age 55 and older who enrolled within 24-hours of testing positive for COVID-19 between Sept. 24 and Dec. 21, 2020, experienced hospitalization. No one died.  Researchers know that the more virus that was present in your body, the worse the impact. “One of our thoughts was: If we can rinse out some of the virus within 24 hours of them testing positive, then maybe we can lower the severity of that whole trajectory,” she says, including reducing the likelihood the virus could get into the lungs, where it was doing permanent, often lethal damage to many. Baxter says the nasal irrigation with saline helps decrease the usual robust attachment. Saline appears to inhibit the virus' ability to essentially make two cuts in itself, called furin cleavage, so it can better fit into an ACE2 receptor once it spots one. Participants self-administered nasal irrigation using either povidone-iodine, that brown antiseptic that gets painted on your body before surgery, or sodium bicarbonate, or baking soda, which is often used as a cleanser, mixed with water that had the same salt concentration normally found in the body. Those who completed nasal irrigation twice daily reported quicker resolution of symptoms regardless of which of two common antiseptics they were adding to the saline water. Eating more spicy foods decreases your risk of early death by 14% Chinese Academy of Medical Sciences, September 7, 2022 According to an international team of researchers led by the Chinese Academy of Medical Sciences, eating spicy foods may be the key to longevity. They found that eating such foods on a regular basis can help prevent people from dying prematurely by 14 percent. While a variety of spicy foods are excellent, one in particular caught their attention. It was noted that consumption of fresh chili pepper, compared to other spicy foods, was most effective in providing people with a lower risk of dying from cancer, ischemic heart disease and diabetes. It's explained that fresh chili pepper's combination of powerful ingredients are responsible for such health-boosting benefits.(1) “Compared with non-fresh spicy foods such as dried chilli pepper, chilli sauce or chilli oil,” says Lu Qi, associate professor at Harvard School of Public Health, “fresh chilli pepper is richer in bioactive ingredients, including capsaicin, vitamin C, and other nutrients such as vitamin A, K, and B6 and potassium.”(1) To conduct the study, the experts from the Chinese Academy of Medical Sciences assessed nearly 490,000 participants. After a follow-up that averaged approximately seven years, 20,224 deaths were noted. Analysis of these people led to the finding that compared to those who ingested spicy foods less than once weekly, people who ate such foods one or two days per week had a 10 percent reduced risk of death. More impressive however, was the discovery that those who enjoyed spicy foods nearly every other day were at a 14 percent lowered risk of death compared to those who ate them less than once a week. In this large prospective study, we observed an inverse association between consumption of spicy foods and total mortality, after adjusting for potential confounders. Compared with those who ate spicy foods less than once a week, those who consumed spicy foods almost every day had a 14% lower risk of death. Inverse associations were also observed for deaths due to cancer, ischemic heart diseases, and respiratory diseases. The associations were consistent in men and women. Meditation holds the potential to help treat children suffering from traumas, difficult diagnoses or other stressors Wayne State University, September 13, 2022 Children actively meditating experience lower activity in parts of the brain involved in rumination, mind-wandering and depression, our team found in the first brain-imaging study of young people under 18 years old. Over-activity in this collection of brain regions, known as the default mode network, is thought to be involved in the generation of negative self-directed thoughts – such as “I am such a failure” – that are prominent in mental disorders like depression. In our study, we compared a simple form of distraction – counting backward from 10 – with two relatively simple forms of meditation: focused attention to the breath and mindful acceptance. Children in an MRI scanner had to use these techniques while watching distress-inducing video clips, such as a child receiving an injection. We found that meditation techniques were more effective than distraction at quelling activity in that brain network. This reinforces research from our lab and others showing that meditation techniques and martial arts-based meditation programs are effective for reducing pain and stress in children with cancer or other chronic illnesses – and in their siblings – as well as in schoolchildren during the COVID-19 pandemic. Researchers know a lot about what is happening in the brain and body in adults while they meditate, but comparable data for children has been lacking. Understanding what is happening in children's brains when they meditate is important because the developing brain is wired differently from the adult brain.  Pace as important as 10,000 steps for health, finds new research University of Sydney and University of South Denmark, September 13, 2022 Two studies, published in JAMA Internal Medicine and JAMA Neurology, monitored 78,500 adults with wearable trackers—making these the largest studies to objectively track step count in relation to health outcomes. The researchers from the University of Sydney, Australia and University of Southern Denmark found lowered risk of dementia, heart disease, cancer and death are associated with achieving 10,000 steps a day. However, a faster stepping pace like a power walk showed benefits above and beyond the number of steps achieved. “The take-home message here is that for protective health benefits people could not only ideally aim for 10,000 steps a day but also aim to walk faster,” said co-lead author Dr. Matthew Ahmadi, Research Fellow at the University of Sydney's Charles Perkins Centre and Faculty of Medicine and Health. Key points: Every 2,000 steps lowered risk of premature death incrementally by 8 to 11 percent, up to approximately 10,000 steps a day. Similar associations were seen for cardiovascular disease and cancer incidence. A higher number of steps per day was associated with a lower risk of all-cause dementia 9,800 steps was the optimal dose linked to lower risk of dementia by 50 percent, however risk was reduced by 25 percent at as low as 3,800 steps a day Feed a virus, starve a bacterial infection? Yale University, September 8, 2022 A new study puts some old folk wisdom to “feed a cold and starve a fever” to the test. In mouse models of disease, Yale researchers looked at the effects of providing nutrients during infection and found opposing effects depending on whether the infections were bacterial or viral.  Mice with bacterial infections that were fed died, while those with viral infections who were fed lived. “We were surprised at how profound the effects of feeding were, both positive and negative,” says senior author Ruslan Medzhitov, David W. Wallace Professor of Immunobiology and a Howard Hughes Medical Institute investigator at Yale School of Medicine. In the first series of experiments, the investigators infected mice with the bacterium Listeria monocytogenes, which commonly causes food poisoning. The mice stopped eating, and they eventually recovered. But when the mice were force fed, they died. The researchers then broke the food down by component and found fatal reactions when the mice were given glucose, but not when they were fed proteins or fats. When the researchers did similar studies in mice with viral infections, they found the opposite effect. Mice infected with the flu virus A/WSN/33 survived when they were force fed glucose, but died when they were denied food or given 2-DG.