Podcasts about jama neurology

Un nuovo studio, pubblicato su JAMA Neurology, ha analizzato oltre 11 milioni di persone e ha scoperto che chi soffre di apnea notturna non trattata ha un rischio più alto di sviluppare il Parkinson. Ne parliamo con la professoressa Carolina Lombardi, responsabile del Centro di Medicina del Sonno dell'Auxologico San Luca di Milano, per capire meglio questa connessione e l'importanza di riconoscere e curare l'apnea nel modo giusto.

Interview with John P. Ney, MD, MPH, author of US Burden of Disorders Affecting the Nervous System: From the Global Burden of Disease 2021 Study. Hosted by Cynthia E. Armand, MD. Related Content: US Burden of Disorders Affecting the Nervous System

Dès la première bouchée d'un biscuit industriel ou d'un plat prêt-à-réchauffer, le cerveau entre en scène. Les aliments ultra-transformés (AUT) — riches en sucres rapides, graisses, sel et additifs — activent rapidement les circuits de la récompense, notamment au niveau du système mésolimbique. Selon une revue de l'Université du Michigan, ces aliments « frappent » le cerveau de manière rapide et intense, stimulant les zones impliquées dans le plaisir, la motivation et l'apprentissage. Résultat : une forte libération de dopamine, comparable à celle observée avec certaines substances addictives. On ressent du plaisir, ce qui incite à recommencer, jusqu'à ce que le cerveau en fasse une habitude automatique.Mais le plaisir n'est qu'une partie de l'histoire. Une étude publiée en 2025 dans Nature Mental Health a montré que les personnes consommant le plus d'aliments ultra-transformés présentaient des altérations des zones sous-corticales du cerveau, notamment le noyau accumbens et l'hypothalamus — deux régions essentielles au contrôle de la faim et de la satiété. Le cerveau perd alors une partie de sa capacité à réguler le comportement alimentaire : la partie rationnelle (celle qui dit “stop”) devient moins influente face à la récompense immédiate.D'autres recherches mettent en évidence des effets inflammatoires. Une revue parue en 2024 dans la revue Nutrients (MDPI) a montré que les AUT favorisent la neuroinflammation et le stress oxydatif. Ces processus entraînent une fragilisation des neurones et altèrent la communication entre différentes zones cérébrales. Autrement dit, les aliments ultra-transformés créent un environnement chimique hostile dans lequel le cerveau fonctionne en surrégime, mais avec moins d'efficacité.Sur le long terme, ces modifications ne sont pas anodines. Une étude publiée dans JAMA Neurology en 2022 a suivi plus de 10 000 adultes pendant dix ans. Résultat : les gros consommateurs d'aliments ultra-transformés présentaient un risque de démence supérieur de 25 % et un risque de déclin cognitif accéléré. La mémoire et les fonctions exécutives (concentration, planification, autocontrole) semblent particulièrement touchées.Bonne nouvelle, pourtant : le cerveau reste plastique. En réduisant la part d'aliments ultra-transformés et en réintroduisant des produits bruts — fruits, légumes, grains entiers, légumineuses —, on peut rééquilibrer les circuits de la récompense et diminuer l'inflammation cérébrale. Autrement dit, le cerveau peut se réparer. Mais il réclame qu'on le traite comme un chef-d'œuvre biologique, pas comme une poubelle à calories rapides. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

What if one side of your body suddenly stopped moving — and your doctor said, “It's a migraine”?Hemiplegic migraines are rare, disorienting, and often confused with strokes. They challenge everything you think you know about how your brain, body, and energy connect.In this episode of Migraine Heroes Podcast, hosted by Diane Ducarme, we explore the science and the story behind this rare form of migraine — one that blurs the line between neurology and mystery. Together, we look at how the body can temporarily lose its flow, and how to gently help it find its rhythm again.In this episode, you'll learn:

Ready to finally break free from alcohol—and stop the cycle of numbing? Start your journey today with the Refresh & Reboot: 30 Day Alcohol-Free Challenge. This self-paced program gives you daily guidance, mindset tools, and video support from Sara to help you thrive through your first 30 days without alcohol. Podcast listeners get 20% off with code PODCAST20 at checkout.

Interview with Helen Kim, PhD, author of Risk of Future Hemorrhage From Unruptured Brain Arteriovenous Malformations: The Multicenter Arteriovenous Malformation Research Study (MARS). Hosted by Cynthia E. Armand, MD. Related Content: Risk of Future Hemorrhage From Unruptured Brain Arteriovenous Malformations

Send comments and feedbackSomatic genetic epilepsies arise from mutations that occur early in fetal development. They are usually only detectable by genetic sequencing of tissue. For these epilepsies, the timing of the mutation is key: For example, research has shown that focal cortical dysplasia type IIB and hemimegaloencephaly are genetically the same disease, but arise from somatic mutations at different developmental time points. This relatively new area of research is discussed by Dr. Alina Ivaniuk and Dr. Christian Bosselmann.Resources:Analysis of 1,386 epileptogenic brain lesions reveals association with DYRK1A and EGFR (Nature Communications 2024 - C. Bosselmann et al.)Neocortical development and epilepsy: Insights from focal cortical dysplasia and brain tumours (The Lancet Neurology 2021 - I. Blumcke et al.)Contribution of somatic Ras/Raf/Mitogen-activated protein kinase variants in the hippocampus in drug-resistant mesial temporal lobe epilepsy (JAMA Neurology 2023 - S. Khoshkhoo et al.)Somatic mosaicism and neurodevelopmental disease (Nature Neuroscience 2018 - AM D'Gama and CA Walsh)BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors (Nature Medicine 2018 - HY Koh et al.)SLC35A2 loss-of-function variants affect glycomic signatures, neuronal fate and network dynamics (Brain 2025 - D Lai et al.)Precise detection of low-level somatic mutation in resected epilepsy brain tissue (Acta Neuropathologica 2019 - NS Sim et al.)Toward a better definition of focal cortical dysplasia: An iterative histopathological and genetic agreement trial (Epilepsia 2021 - I Blumcke et al.)Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: A retrospective multicentre cohort study (The Lancet Neurology 2020 - HJ Lamberink et al.) Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.Let us know how we're doing: podcast@ilae.org.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Instagram, and LinkedIn.

Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues tested the ability of an AI model to differentiate between Parkinson disease and other neurodegenerative disorders when paired with MRI. He joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH to discuss. Related Content: A Large Proportion of Parkinson Disease Diagnoses Are Wrong—Here's How AI Could Help Automated Imaging Differentiation for Parkinsonism

Interview with Colin P. Derdeyn, MD, author of Intravenous Argatroban or Eptifibatide in Patients Undergoing Mechanical Thrombectomy: A Subgroup Analysis of the MOST Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Intravenous Argatroban or Eptifibatide in Patients Undergoing Mechanical Thrombectomy

To subscribe to our podcast and YouTube channel visit: https://www.youtube.com/@davisphinneyfdn/podcasts This episode of the Parkinon's Podcast features the full, unedited audio from a Live Well Today Webinar. During this live webinar, Dr. Corcos, Professor of Physical Therapy and Human Movement Sciences, shared insights from decades of research focused on the benefits of exercise for people with Parkinson's. Listen in as Dr. Corcos discusses the latest findings in Parkinson's exercise science and offers practical takeaways for incorporating effective movement strategies into everyday life.  Some links discussed in this webinar: SPARX Phase 2 Trial--https://jamanetwork.com/journals/jamaneurology/fullarticle/2664948 Dr. Corcos' Exercise Advice Article--https://journals.sagepub.com/doi/10.3233/JPD-230277 Cardio Pulmonary Exercise Test Article-https://journals.sagepub.com/doi/10.1177/1877718X251330814 Industrial Chemicals and Parkinson's Blog-- https://davisphinneyfoundation.org/industrial-chemicals-pesticides-and-parkinsons/ Climbing and Parkinson's Blog-- https://davisphinneyfoundation.org/stay-moving-with-parkinsons-tai-chi-ping-pong-and-rock-climbing/ ---- Speaker Bio Daniel Corcos, PhD Professor of Physical Therapy & Human Movement Sciences  Daniel Corcos obtained his PhD in Motor Control from the University of Oregon after obtaining his Master's Degree in Psychology. The primary research interests of Dr. Corcos are aimed at helping people with Parkinson's disease improve their quality of life, improve their mobility and cognition, and slow down the rate at which their disease progresses. Integrating neuroscience and expertise in conducting clinical trials, the research of Dr. Corcos focuses on interventions (such as resistance exercise, endurance exercise, stretching and balance training) that aim to reduce the symptoms of the disease and delay the rate at which the disease progresses. Within this context, Dr. Corcos uses exercise interventions whose dose (frequency, intensity, time and type) can be precisely controlled to achieve these goals and thereby develops and integrates laboratory-based interventions that people with Parkinson's disease can employ in their local community. His current research, published in JAMA Neurology suggests that high intensity endurance slows down the rate at which Parkinson's disease progresses. These findings have been covered in the New York Times and the general press world-wide. Dr. Corcos lectures nationally and internationally to physicians, neuroscientists, and people with the disease on the benefits of exercise for those with Parkinson's disease.

Interview with Dennis J. Rivet II, MD, author of GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension. Hosted by Cynthia E. Armand, MD. Related Content: GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension

Most of us are familiar with the idea that you need to take 10 thousand steps per day to stay healthy but getting to this magic number is not that easy. The 10,000-step target first became popular in Japan in the 1960s. A clockmaker capitalising on people's new interest in fitness following the 1964 Tokyo Olympic Games made a pedometer with a name that, when written in Japanese characters, resembled a walking man and coincidentally translated as “10,000-steps metre.” A study of over 78,000 people in the UK between 2013 and 2015 using wearable trackers was published in the journals JAMA Internal Medicine and JAMA Neurology. Where did we get the number 10 thousand from? Does that mean that we do not need to take 10 steps? So how many steps should I be aiming for per day? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: ⁠Can you eat eggs everyday?⁠ ⁠What is Lucky Girl syndrome, this new method that is all the rage on Tik Tok?⁠ ⁠Which type of wine is best for your health?⁠ A podcast written and realised by Amber Minogue. First broadcast: 19/1/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices

Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues tested the ability of an AI model to differentiate between Parkinson disease and other neurodegenerative disorders when paired with MRI. He joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH to discuss. Related Content: A Large Proportion of Parkinson Disease Diagnoses Are Wrong—Here's How AI Could Help Automated Imaging Differentiation for Parkinsonism

Interview with Manuel Comabella, MD, author of Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome. Hosted by Cynthia E. Armand, MD. Related Content: Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome

Interview with Richard B. Lipton, MD, author of Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder. Hosted by Cynthia E. Armand, MD. Related Content: Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder

While large retailers may weather the storm, independent businesses are struggling to absorb rising costs tied to new trade policies. "CBS Mornings" hears from one Los Angeles entrepreneur facing tough choices. Lori Vallow Daybell was in an Arizona court Monday to represent herself in a trial involving the killing of her fourth husband, Charles Vallow, in 2019. In her opening statement, Vallow said the evidence will show it was self defense, but prosecutors argued she conspired with her brother to kill Vallow, who had filed for divorce, to collect a $1 million life insurance policy. Two new studies in JAMA Neurology show some diabetes and popular weight loss drugs could help to protect against dementia. CBS News medical contributor Dr. Celine Gounder joins "CBS Mornings" to explain what researchers found. The Florida Gators won their first NCAA basketball title since 2007. Will Richard, who hit four three-pointers in the first half, speaks about the big win, what he'll remember from this season and the next steps in his career. Deja Kelly has turned her platform into a personal brand, but she says having the right support system — from a financial advisor to her "momager" — is key to staying grounded in the new NIL economy. With just days to go before liftoff, Gayle King gets a surprise sendoff on "CBS Mornings" from friends and famous faces including Tom Hanks, William Shatner, Bill Nye and Megan Rapinoe. Nearly a decade since her last Broadway role, Idina Menzel is back, this time climbing through midair as a grieving mother who finds healing and hope in California's redwood forest. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

Interview with Steven J. Warach, MD, PhD, author of Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation: A Pragmatic, Response-Adaptive Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation

Interview with David J. Seiffge, MD, author of Location and Timing of Recurrent, Nontraumatic Intracerebral Hemorrhage. Hosted by Cynthia E. Armand, MD. Related Content: Location and Timing of Recurrent, Nontraumatic Intracerebral Hemorrhage

As the earth continues to get warmer and we see record high temperatures across the globe, scientists tell us that this pattern is going to continue and be more common. Higher temperatures, more frequently has led to more heat strokes and other conditions when people aren't prepared for this situation.  Additionally, people with neurodegenerative diseases like Parkinson's are at greater risk for heat related complications, A recent article published in JAMA Neurology, describes the issue, what to look for, and how we, as individuals and community, can help to prevent people from heat related complications. It was co-written by my guest today, Indu Subramanian, MD, a neurologist and movement disorders researcher at the University of California, Los Angeles (UCLA), and Al Saad, MD, a neurologist with expertise in climate change at the University of Colorado. With summer around the corner, this is a great time to prepare for the heat and work with your healthcare team on a plan to prevent any heat related issues. We as a community need to look out for our neighbors, friends and family. Our neighbors   may be isolated or scared if they have Parkinson's diseasae or are older. As a community, we should come together to identify people who may need our help during a difficult situation such as heatwaves and higher temperatures, especially in areas in the world where they are not prepared to assist. We should keep in touch, check in, offer some water.   Learn all about how to prepare, provent, find help as well as recognizing the symptoms of heatstroke on this episode of the Parkinson's Experience. https://www.parkinsonsecrets.com/  https://parkinsonsnewstoday.com/news/heat-intolerance-rising-parkinsons-risk-climbing-temperatures/ https://www.uclahealth.org/providers/indu-subramanian https://www.dbsandme.com/en.html  

Interview with Wei-Hsuan Lo-Ciganic, PhD, author of Cardiovascular Safety of Anti-CGRP Monoclonal Antibodies in Older Adults or Adults With Disability With Migraine. Hosted by Cynthia E. Armand, MD. Related Content: Cardiovascular Safety of Anti-CGRP Monoclonal Antibodies in Older Adults or Adults With Disability With Migraine

Most of us are familiar with the idea that you need to take 10 thousand steps per day to stay healthy but getting to this magic number is not that easy. The 10,000-step target first became popular in Japan in the 1960s. A clockmaker capitalising on people's new interest in fitness following the 1964 Tokyo Olympic Games made a pedometer with a name that, when written in Japanese characters, resembled a walking man and coincidentally translated as “10,000-steps metre.” A study of over 78,000 people in the UK between 2013 and 2015 using wearable trackers was published in the journals JAMA Internal Medicine and JAMA Neurology. Where did we get the number 10 thousand from? Does that mean that we do not need to take 10 steps? So how many steps should I be aiming for per day? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Can you eat eggs everyday? What is Lucky Girl syndrome, this new method that is all the rage on Tik Tok? Which type of wine is best for your health? A podcast written and realised by Amber Minogue. First broadcast: 19/1/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices

Interview with Jordan L. Schultz, PharmD, author of β-Blocker Use and Delayed Onset and Progression of Huntington Disease. Hosted by Cynthia E. Armand, MD. Related Content: β-Blocker Use and Delayed Onset and Progression of Huntington Disease

Interview with Giovanni B. Frisoni, MD, author of Alzheimer Disease as a Clinical-Biological Construct—An International Working Group Recommendation. Hosted by Cynthia E. Armand, MD. Related Content: Alzheimer Disease as a Clinical-Biological Construct—An International Working Group Recommendation

A recent practice guideline provides updated evidence-based conclusions and recommendations regarding in utero effects of anti-seizure medications and folic acid supplementation on the prevalence of major congenital malformations, adverse perinatal outcomes, and neurodevelopmental outcomes. Dr. Parthvi Ravat interviewed Dr. Alison Pack about the guideline, which was produced by the American Academy of Neurology, American Epilepsy Society, and Society for Maternal-Fetal Medicine.Review the practice guideline: Teratogenesis, perinatal, and neurodevelopmental outcomes after in utero exposure to antiseizure medication (Neurology, May 2024)Other studies mentioned in the episode: Risk of major congenital malformations and exposure to antiseizure medication monotherapy (JAMA Neurology, March 2024) Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.Let us know how we're doing: podcast@ilae.org.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, X (Twitter), Instagram, and LinkedIn.

Interview with Rachel Grashow, PhD, MS, and Aaron L. Baggish, MD, authors of Perceived Chronic Traumatic Encephalopathy and Suicidality in Former Professional Football Players. Hosted by Cynthia E. Armand, MD. In the US, you can call, text, or chat 988, the Suicide and Crisis Lifeline. Related Content: Perceived Chronic Traumatic Encephalopathy and Suicidality in Former Professional Football Players

Dr. Gregg Day talks with Dr. Sebastian Palmqvist about the use of blood biomarkers to streamline the diagnostic workup and treatment of Alzheimer disease. Read the related article in JAMA Neurology. Disclosures can be found at Neurology.org.

Interview with Peter Vajkoczy, MD, author of Localized Nicardipine Release Implants for Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage: A Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Localized Nicardipine Release Implants for Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage

Dr. Matthew Barrett talks with Dr. Michael S. Okun about the caution and deliberation needed in understanding Parkinson disease biomarkers. Read the related viewpoint piece in JAMA Neurology. Disclosures can be found at Neurology.org.

Interview with Allison W. Willis, MD, MS, author of Direct-Acting Oral Anticoagulants and Antiseizure Medications for Atrial Fibrillation and Epilepsy and Risk of Thromboembolic Events. Hosted by Cynthia E. Armand, MD. Related Content: Direct-Acting Oral Anticoagulants and Antiseizure Medications for Atrial Fibrillation and Epilepsy and Risk of Thromboembolic Events

Most of us are familiar with the idea that you need to take 10 thousand steps per day to stay healthy but getting to this magic number is not that easy. The 10,000-step target first became popular in Japan in the 1960s. A clockmaker capitalising on people's new interest in fitness following the 1964 Tokyo Olympic Games made a pedometer with a name that, when written in Japanese characters, resembled a walking man and coincidentally translated as “10,000-steps metre.” A study of over 78,000 people in the UK between 2013 and 2015 using wearable trackers was published in the journals JAMA Internal Medicine and JAMA Neurology. Where did we get the number 10 thousand from? Does that mean that we do not need to take 10 steps? So how many steps should I be aiming for per day? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Can you eat eggs everyday? What is Lucky Girl syndrome, this new method that is all the rage on Tik Tok? Which type of wine is best for your health? A podcast written and realised by Amber Minogue. First broadcast: 19/01/2023 Learn more about your ad choices. Visit megaphone.fm/adchoices

Interview with Urs Fischer, MD, MSc, author of Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation: Post Hoc Analysis of the ELAN Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation

Interview with Churl-Su Kwon, MD, MPH, author of Association of New-Onset Seizures With SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Hosted by Cynthia E. Armand, MD. Related Content: Association of New-Onset Seizures With SARS-CoV-2 Vaccines

Interview with Anne Kerbrat, MD, PhD, author of High-Efficacy Therapy Discontinuation vs Continuation in Patients 50 Years and Older With Nonactive MS. Hosted by Cynthia E. Armand, MD. Related Content: High-Efficacy Therapy Discontinuation vs Continuation in Patients 50 Years and Older With Nonactive MS

Dr. Deanna Saylor talks with Drs. Gretchen Birbeck and Melody Asukile about ways to improve global collaboration among neurologists. Read the related article in JAMA Neurology. Disclosures can be found at Neurology.org.

Interview with Andrea L. C. Schneider, MD, PhD, author of Posttraumatic Epilepsy and Dementia Risk. Hosted by Cynthia E. Armand, MD. Related Content: Posttraumatic Epilepsy and Dementia Risk

Interview with Jesper Hallas, MD, DMSc, author of Risk of Stroke and Myocardial Infarction Among Initiators of Triptans. Hosted by Cynthia E. Armand, MD. Related Content: Risk of Stroke and Myocardial Infarction Among Initiators of Triptans

Un análisis de sangre permite diagnosticar la enfermedad del Alzheimer con una precisión de alrededor del 95%, según los resultados de un estudio publicado por la revista JAMA Neurology, en el que han participado investigadores del Hospital de Sant Pau (Barcelona).

Interview with Stevie Hendriks, PhD, author of Risk Factors for Young-Onset Dementia in the UK Biobank. Hosted by Cynthia E. Armand, MD. Related Content: Risk Factors for Young-Onset Dementia in the UK Biobank

Interview with Zhongrong Miao, MD, author of Alberta Stroke Program Early Computed Tomography Score, Infarct Core Volume, and Endovascular Therapy Outcomes in Patients With Large Infarct: A Secondary Analysis of the ANGEL-ASPECT Trial. Hosted by Cynthia E. Armand, MD. Read Transcript Related Content: Alberta Stroke Program Early Computed Tomography Score, Infarct Core Volume, and Endovascular Therapy Outcomes in Patients With Large Infarct

Interview with Ari J. Green, MD, author of Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis. Hosted by Cynthia E. Armand, MD. Related Content: Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis

Interview with Richard A. Bernstein, MD, PhD, author of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: 3-Year Results From the STROKE AF Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease

Dr. Halley Alexander talks with Dr. Sándor Beniczky about the use of artificial intelligence to accurately interpret routine clinical electroencephalograms. Read the relate article in JAMA Neurology. Visit NPUb.org/Podcast for associated article links.

Interview with Ann C. McKee, MD, author of Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts. Hosted by Cynthia E. Armand, MD. Related Content: Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts

Dr. Jason Crowell talks with Dr. Frederic Schaper about legion-related epilepsy mapping to specific brain networks.  Read the related article in JAMA Neurology.  Visit NPUb.org/Podcast for additional podcasts and associated article links.

Scientists who study the mind and brain have always been drawn to periods of intense change—to those life stages marked by rapid transformation. Infancy is one of those periods, of course. Adolescence is another. But there's a less-discussed time of life when our brains and minds have to reconfigure: the window surrounding when we become parents.  My guests today are Dr. Winnie Orchard and Dr. Jodi Pawluski. Winnie is a cognitive neuroscientist and postdoctoral scholar at the Yale Child Study Center. Jodi is a neuroscientist, author, and podcaster affiliated with the University of Rennes in France. Both are experts in the neural and cognitive changes that surround pregnancy, motherhood, and parenthood more generally.  Here, we talk about the idea of "matrescence" as a distinctive developmental stage. We discuss the research around memory loss in early motherhood, as well as findings that certain brain areas get fine-tuned during this period. We talk about postpartum anxiety, depression, and psychosis, and what may be causing them. We consider the finding that having children—and, in fact, having more children—seems to confer a protective effect on the aging brain. Throughout we talk about which of these changes also occur in fathers and other non-birthing parents. And we consider the difficulty of scientifically studying a period of life—parenthood—that is not only rife with social and psychological changes, but also fraught with expectations and narratives. Alright friends, I hope you enjoy this one. As you'll hear, this research area is very much still in its infancy. There are definitely some provocative findings. But maybe more exciting are all the questions that remain. Without further ado, here's my chat with Dr. Winnie Orchard and Dr. Jodi Pawluski. Enjoy!   A transcript of this episode will be available soon.   Notes and links 2:45 – For more on the relationship between adolescence and “matrescence,” see this recent review paper by Winnie and colleagues in Trends in Cognitive Sciences. 6:00 – For discussions surrounding the idea of “mommy brain,” see Jodi's podcast, ‘Mommy Brain Revisited.' See also this recent editorial by Jodi and colleagues in JAMA Neurology.  17:00 – A recent meta-analysis on cognitive impairment during pregnancy.  25:00 – A study by Winnie and colleagues showing subjective—but not objective—memory deficits in mothers one year after giving birth.   26:45 – An influential study showing structural changes in the brain following pregnancy. The same study also found that some of these changes correlated with measures of maternal attachment. 28:00 – A recent review article by Jodi and colleagues on the idea of neural fine-tuning in early motherhood.   41:45 – A recent review paper by Jodi and colleagues about the neural underpinnings of postpartum depression and anxiety.  44:00 – A review paper about postpartum psychosis.  51:00 – A study on the prevalence of postpartum depression across cultures.  58:00 – A 2014 review of research on mother-child synchrony. 1:00:00 – A recent study by Winnie and colleagues looking at how having children affects later life brain function. Another study by Winnie and colleagues on the same topic.  1:13:00 – Several studies have documented general changes in “Big 5” personality factors as people age. A study examining this in both American and Japanese participants is here. 1:18:00 – Since we recorded this interview, the publication date for the English version of Jodi's book has been scheduled. It comes out in September 2023—more info here.   Recommendations  Dr. Orchard recommends: Baby Brain, Sarah McKay Mother Brain, Chelsea Conaboy   Dr. Pawluski recommends: Matrescence, by Lucy Jones After the Storm, by Emma Jane Unsworth   Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the Templeton World Charity Foundation to UCLA. It is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Our transcripts are created by Sarah Dopierala. Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here! We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com.  For updates about the show, visit our website or follow us on Twitter: @ManyMindsPod.

Interview with Kristine Yaffe, MD, author of Dementia Risk and Disadvantaged Neighborhoods. Hosted by Cynthia E. Armand, MD. Related Content: Dementia Risk and Disadvantaged Neighborhoods

Read the related article in JAMA Neurology. 

Dr. Roy Hamilton talks with Dr. Kenneth Langa, about the prevalence of dementia and mild cognitive impairment in the US. Read the full article in JAMA Neurology. This episode is brought to you by Mass General Brigham Department of Neurology, please visit us at www.massgeneralbrigham.org.

Dr. Dan Ackerman talks with Dr. David Seiffge, about the use of oral anticoagulants on ischemic stroke. Read the full article in JAMA Neurology. This episode is brought to you by Mass General Brigham Department of Neurology, please visit us at www.massgeneralbrigham.org.