Podcasts about Nature Neuroscience

Imagine being trapped in your own body, unable to move or communicate effectively. This may seem like a nightmare, but it is a reality for many people living with brain or spinal cord injuries.We're re-releasing one of our favorite episodes from the archives: our 2024 conversation with Jaimie Henderson, a Stanford neurosurgeon leading groundbreaking research in brain-machine interfaces. Henderson shares how multiple types of brain implants are currently being developed to treat neurological disorders and restore communication for those who have lost the ability to speak. We also discuss the legacy of the late Krishna Shenoy and his transformative work in this field.Learn moreHenderson's Neural Prosthetics Translational LabBrainGate Consortium – "Turning thought into action"‘Unprecedented' level of control allows person without use of limbs to operate virtual quadcopter (University of Michigan, 2025)Brain Implants Helped 5 People Recover From Traumatic Injuries (New York Times, 2023)The man who controls computers with his mind (New York Times Magazine, 2022)Software turns ‘mental handwriting' into on-screen words, sentences (Stanford Medicine, 2021)Related video: Wu Tsai Neurosciences Institute, 2021Related publication: Nature, 2021Learn about the work of the late Krishna ShenoyKrishna V. Shenoy (1968–2023) (Nature Neuroscience, 2023)Krishna Shenoy, engineer who reimagined how the brain makes the body move, dies at 54 (Stanford Engineering, 2023)Episode CreditsThis episode was produced by Michael Osborne at 14th Street Studios, with sound design by Morgan Honaker. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute and supported in part by the Knight Iniative for Brain Resilience.Get in touchWe want to hear from your neurons! Email us at at neuronspodcast@stanford.edu.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Man kennt es... Vor der Klausur steht man vor einem Berg an Fakten, der unbezwingbar scheint. Wie gehe ich das Lernen an, sodass der Inhalt bestenfalls sogar langfristig in meinem Hirn hängen bleibt? Um euch den aktuellsten Stand der Lernforschung zu liefern, haben wir Michail aus Hamburg eingeladen! Er ist selbst Medi und beschäftigt sich mit der studentischen Forschungsgruppe ME-Learn mit diversen Lernmethoden. Wir liefern euch in dieser Folge wertvolle, evidenzbasierte Tipps für eure nächste Klausurenphase. Wir reden auch darüber, wie Dank Effizienz noch viel Zeit für Hobbies bleibt

Dr Lisa Feldman Barrett, who is in the top one percent of most cited scientists in the world for her revolutionary research in psychology and neuroscience. She is a Distinguished Professor of Psychology at Northeastern University, and also holds appointments at Harvard Medical School and Massachusetts General Hospital, where she is Chief Science Officer for the Center for Law, Brain & Behavior. In addition to the books Seven and a Half Lessons About the Brain and How Emotions are Made, Dr. Barrett has published over 260 peer-reviewed, scientific papers appearing in Science, Nature Neuroscience, and other top journals in psychology and cognitive neuroscience, as well as six academic volumes. She has also given a popular TED talk with over 6.5 million views. From this conversation, you'll learn: — Dr Barrett's groundbreaking theory of emotions and its implications for mental health and wellbeing — How emotional "granularity" can enhance your quality of life — Why everything we see is a "concept" and why this matters — Dr Barrett's thoughts on free will and personal responsibility. And more. You can learn more about Dr Barrett's work by going to: www.lisafeldmanbarrett.com --- Dr. Lisa Feldman Barrett is a psychologist, neuroscientist, professor, bestselling author, and one of the most cited scientists in the world. She received a National Institutes of Health Director's Pioneer Award for her revolutionary research on emotion in the brain. These highly competitive, multimillion dollar awards are given to scientists of exceptional creativity who are expected to transform biomedical and behavioral research. She also received a Guggenheim Fellowship in 2019, the APS Mentor Award for Lifetime Achievement in 2018, and the APA Distinguished Scientific Contribution Award in Psychology in 2021. Among her many accomplishments, Dr. Barrett has testified before Congress, presented her research to the FBI, consulted to the National Cancer Institute, appeared on Through The Wormhole with Morgan Freeman and The Today Show with Maria Shriver, and been a featured guest on public television and podcast and radio programs worldwide. She is also an elected fellow of the American Academy of Arts & Sciences and the Royal Society of Canada. --- Interview Links: — Seven and a Half Lessons About the Brain - Lisa Feldman Barrett: https://amzn.to/3CWM1VQ — How Emotions are Made - Lisa Feldman Barrett: https://amzn.to/3Rx1BeT — Dr Barrett's website: www.lisafeldmanbarrett.com — Matter and Consciousness - Dr Iain McGilchrist: https://bit.ly/3RGSQz0 3 Books Dr Porges Recommends Every Therapist Should Read: — Between us by Batja Mesquita - https://amzn.to/3FdYkxT — The End of Trauma by George Bonanno - https://amzn.to/3AW1fbL — How Emotions are Made by Lisa Feldman Barrett - https://amzn.to/3GVdxFl

Send us a textIn this episode, Joe sits down with Dr. Lisa Feldman Barrett, a leading neuroscientist and author of How Emotions Are Made, to explore groundbreaking insights on how emotions are formed and how we can better understand and regulate them. Together, they dive deep into the science behind emotions, how the brain predicts our feelings, and how we can gain more emotional agency in our personal and professional lives. Joe and Dr. Barrett cover:The theory of constructed emotions and how emotions are predictions, not reactionsThe role of the brain in regulating the body and how it shapes emotional experiencesWhy uncertainty feels like anxiety—and how to reframe itHow emotional granularity can help us build better emotional vocabulary and controlPractical steps to improve emotional regulation and decision-makingThe impact of body budgeting on mood, stress, and overall healthWhether you're leading a team, navigating personal relationships, or simply trying to better understand your emotional life, this conversation will give you powerful tools to enhance your emotional intelligence and well-being.Lisa Feldman Barrett, PhD, is among the top 0.1% most cited scientists in the world for her revolutionary research in psychology and neuroscience. She is a University Distinguished Professor of Psychology at Northeastern University. She also holds appointments at Harvard Medical School and Massachusetts General Hospital, where she is Chief Science Officer for the Center for Law, Brain & Behavior.In addition to the books Seven and a Half Lessons About the Brain and How Emotions are Made, Dr. Barrett has published over 275 peer-reviewed, scientific papers appearing in Science, Nature Neuroscience, and other top journals in psychology and cognitive neuroscience, as well as six academic volumes published by Guilford Press. She writes regularly about science in the popular press, including The New York Times, The Guardian, Scientific American, BBC Science Focus, Popular Science, Nautilus, BigThink, Cosmopolitan,  Time magazine, MIT Technology Review, and more (see full list). Her popular TED talk has been viewed over 7 million times.A Special Thanks to Our Sponsors!Veteran-founded Adyton. Step into the next generation of equipment management with Log-E by Adyton. Whether you are doing monthly inventories or preparing for deployment, Log-E is your pocket property book, giving real-time visibility into equipment status and mission readiness. Learn more about how Log-E can revolutionize your property tracking process here!Meet ROGER Bank—a modern, digital bank built for military members, by military members. With early payday, no fees, high-yield accounts, and real support, it's banking that gets you. Funds are FDIC insured through Citizens Bank of Edmond, so you can bank with confidence and peace of mind. Visit

125. EPIZÓDA / Integrovaná informačná teória sa snaží vysvetliť vedomie už dvadsať rokov. Za touto teóriou stoja aj známi neurovedci ako Ch. Koch a G. Tononi. Najnovšie im v prestížnom vedeckom žurnáli, Nature Neuroscience, vyšiel aj článok o agenciálnej kauzalite, a v inom časopise aj o tom, ako by mohli mať ľudia slobodnú vôľu. Navyše, uvadzájú aj to, ako by bolo možné matematicky vyrátať množstvo slobodnej vôle. Najnovšie publikácie o slobodnej vôli v IIT teórii vedomia si pre túto epizódu naštudovali neurovedec Peter Jedlička a fyzik Jaro Varchola.----more---- + + vypočujte si všetky extra časti a podporte tvorbu Kvanta ideí

Professor Sara C. Mednick is a cognitive neuroscientist at the University of California, Irvine and author of The Hidden Power of the Downstate (Hachette Go!, pub date: April, 2022) and Take a Nap! Change Your Life. (Workman). She is passionate about understanding how the brain works through her research into sleep and the autonomic nervous system. Dr. Mednick's seven-bedroom sleep lab works literally around-the-clock to discover methods for boosting cognition by napping, stimulating the brain with electricity, sound and light, and pharmacology. Her lab also investigates how the menstrual cycle and aging affect the brain. Her science has been continuously federally funded (National Institute of Health, National Science Foundation, Department of Defense Office of Naval Research, DARPA).Dr. Mednick was awarded the Office Naval Research Young Investigator Award in 2015. Her research findings have been published in such leading scientific journals as Nature Neuroscience and The Proceedings from the National Academy of Science, and covered by all major media outlets. She received a BA from Bard College, Annandale-on-Hudson, NY, in Drama/Dance. After college, her experience working in the psychiatry department at Bellevue Hospital in New York, inspired her to study the brain and how to make humans smarter through better sleep. She received a PhD in Psychology from Harvard University, and then completed a postdoc at the Salk Institute for Biological Studies and UC San Diego. She resides in San Diego, CA. SHOWNOTES:

Are you really tapping into intuition, or are your emotions fooling you?In this episode, Professor Joel Pearson, leading neuroscientist and researcher, breaks down the real science behind intuition—debunking common myths and revealing how to train your brain for better decision-making.We dive into:✅ What intuition actually is (hint: it's not just a feeling)✅ When to trust vs. ignore your gut instinct✅ How emotions like stress, anxiety, and excitement distort intuition✅ The 5-step "SMILE" framework to sharpen your decision-making✅ How AI will soon enhance human intuitionJoel has spent a decade studying intuition in the lab, discovering how our unconscious mind influences choices—sometimes for the better, sometimes leading us astray. If you're interested in neuroscience, psychology, or making smarter life choices, this episode is a must-listen.Listen now & start making better decisions today.ABOUT PROFESSOR JOEL PEARSONProfessor Joel Pearson is a world-leading neuroscientist, entrepreneur, and expert in human intuition, decision-making, and the science of consciousness. He is the Director of the Future Minds Lab at the University of New South Wales (UNSW) in Sydney, where he leads cutting-edge research on intuition, perception, and mental imagery—helping people and businesses unlock better decision-making strategies.With a background in neuroscience and psychology, Joel has spent over a decade studying how the brain processes unconscious information, how intuition works, and when we should (and shouldn't) trust our gut instincts. His work has been featured in Forbes, The Guardian, BBC, and Nature Neuroscience, and he regularly speaks on how scientific intuition can enhance performance in business, leadership, and everyday life.Joel is also the author of The Intuition Toolkit, where he introduces the SMILE framework, a five-step model to train and refine intuition using neuroscience-backed principles. His expertise has made him a sought-after speaker for Fortune 500 companies, elite athletes, and top executives looking to sharpen their cognitive edge.Currently, Joel is pioneering new research at the intersection of AI and human intuition, exploring how technology can enhance decision-making and help people navigate an increasingly complex world.CONNECT WITH JOELWebsite:https://www.profjoelpearson.com/The Intuition Toolkit Book:https://a.co/d/4rs9MEfCONNECT OWL & KEYGrab a copy of the Strategic Planning for Life bookA perfect gift for yourself or for your growth-oriented friend or family member.https://a.co/d/g8NBjQb UNLOCKED MembershipJoin the community and membership to tap into the ultimate at-your-fingertips, when-you-need-it-most life design resources.https://www.owlandkey.co/membership Level up with a 1:1 Expert Guided ExperienceTransform your life faster and with greater levels of success.https://www.owlandkey.co/coachingHelp your team thrive with our @Work PlatformUnlock growth, performance and wellbeing.https://www.owlandkey.co/at-work

"Part of the reason I stay super busy is bc if I stop to rest l'll ruminate. And if I ruminate, I start spiraling. And if I spiraling I'm like a nosediving plane" Sound familiar? Discover the ANSWER to WHY you get stuck in your most annoying perfectionist tendencies, like ruminating, catastrophizing, overthinking every small mistake etc. Plus the 6 reasons your perfectionist brain holds on to outdated habits,  how chronic stress impacts your brain's ability to change, the role of back and white thinking in reinforcing unhelpful neural pathways, why past experiences trick your brain into seeing danger everywhere and how to stop your worries from becoming self-fulfilling prophecies.  On paper, you've got it together— isn't it time you felt like it? Whether it's becoming much more DECISIVE in everything you do, stop playing out worst case scenarios in your head or JOYFULLY PRESENT AMBITIOUS again, Perfectionism Optimized, private 1-1 coaching gives you the life-long skills to *finally feel* as amazing on the inside as your life looks on the outside. Get your stress-free start today at https://courtneylovegavin.com/rewire TIMESTAMPS:00:00–How to finally take charge of ruminating02:16–Missed the last episode? Here's a quick recap04:06–What happens when your brain gets it wrong06:09–Why perfectionist brains resists learning from mistakes07:40–6 sneaky reasons your brain ignores new info08:23–How chronic stress keeps your brain stuck10:20–Why your brain clings to old patterns11:42–The hidden reason you avoid discomfort12:51–When your brain blows things out of proportion13:49–How black-and-white thinking is like wearing blinders15:19–Why past experiences warp your reactions19:34–How to update your brain so you can get unstuck21:09–One small shift to start seeing change today The first step in rewiring Resources Mentioned In Episode 250:Take your first step in rewiring Perfect Start Introductory SessionMagic Skill for Control of Emotions [Neuroscience Series #1] Perfectionism Rewired Ep. 248How Perfectionist Brain *Actually* Works [Neuroscience Series #2] Perfectionism Rewired Ep. 249When Taking A Few Deep Breaths Isn't Enough Perfectionism Rewired Ep. 192Will Save Your Sanity(might change your life) Perfectionism Rewired Ep. 193 Citations/Sources:Bar, M. (2009). The proactive brain: memory for predictions. Philosophical Transactions of the Royal Society B Biological Sciences, 364(1521), 1235–1243. https://doi.org/10.1098/rstb.2008.0310Barrett, L. F., & Simmons, W. K. (2015). Interoceptive predictions in the brain. Nature Reviews Neuroscience, 16(7), 419–429. https://doi.org/10.1038/nrn3950Braem, S., Coenen, E., Klaas Bombeke, Bochove, van, & Wim Notebaert. (2015). Open your eyes for prediction errors. Cognitive Affective & Behavioral Neuroscience, 15(2), 374–380. https://doi.org/10.3758/s13415-014-0333-4Clark, A. (2013). Whatever next? Predictive brains, situated agents, and the future of cognitive science. Behavioral and Brain Sciences, 36(3), 181–204. https://doi.org/10.1017/s0140525x12000477Handley, A. K., Egan, S. J., Kane, R. T., & Rees, C. S. (2014). The relationships between perfectionism, pathological worry and generalised anxiety disorder. BMC Psychiatry, 14(1). https://doi.org/10.1186/1471-244x-14-98Kummer, K., Mattes, A. & Stahl, J. Do perfectionists show negative, repetitive thoughts facing uncertain situations?. Curr Psychol (2023). https://doi.org/10.1007/s12144-023-04409-3Lital Yosopov, Saklofske, D. H., Smith, M. M., Flett, G. L., & Hewitt, P. L. (2024). Failure Sensitivity in Perfectionism and Procrastination: Fear of Failure and Overgeneralization of Failure as Mediators of Traits and Cognitions. Journal of Psychoeducational Assessment, 42(6), 705–724. https://doi.org/10.1177/07342829241249784Mattes, A., Mück, M., & Stahl, J. (2022). Perfectionism-related variations in error processing in a task with increased response selection complexity. Personality Neuroscience, 5. https://doi.org/10.1017/pen.2022.3‌McNally, G. P., Johansen, J. P., & Blair, H. T. (2011). Placing prediction into the fear circuit. *Trends in Neurosciences*, *34*(6), 283–292. https://doi.org/10.1016/j.tins.2011.03.005‌Meyer, A., & Wissemann, K. (2020). Controlling parenting and perfectionism is associated with an increased error-related negativity (ERN) in young adults. *Social Cognitive and Affective Neuroscience*, *15*(1), 87–95. https://doi.org/10.1093/scan/nsaa018‌Roy, M., Shohamy, D., Daw, N., Jepma, M., Wimmer, G. E., & Wager, T. D. (2014). Representation of aversive prediction errors in the human periaqueductal gray. *Nature Neuroscience*, *17*(11), 1607–1612. https://doi.org/10.1038/nn.3832‌ Perfectionism Rewired is committed to neuroscience truth and accuracy through a perfectionist affirming lens, offering cutting-edge research on perfectionism, neuroplasticity + interoception techniques for the practical perfectionist who wants to enjoy the life you've worked so hard to create instead of obsolete advice to "overcome your perfectionism"

What do you know about matrescence? Most people will agree that everything changes with parenthood, and that's what this term covers: the process of becoming a mother. Yet, despite shared private understanding and a large body of recent research on all the physiological and mental effects, many policies and medical processes continue to ignore what mothers have always known.Lucy Jones is a journalist and the author of Matrescene: On The Metamorphosis of Pregnancy, Childbirth, and Motherhood. In this episode, we delve into what's lacking in support for matrescence and why, and how ongoing research, policy changes, and sharing information through resources like Lucy's book can help change the conversation. Whether you're already a mother, are considering becoming one, or support one in any way, Lucy's insights will be enlightening and empowering.Discover the details of matrescence and why we need to talk more about it:The origins and importance of having a word for this universal, natural experience;The impact of not having enough information in the early months and years of parenthood;The permanent changes the brain goes through during this period;The social disconnect between the expectation to give birth and the lack of support.Related Links:Matrescence: On Pregnancy, Childbirth, and Motherhood by Lucy Jones - https://bookshop.org/p/books/matrescence-on-the-mind-body-spirit-transformations-of-pregnancy-childbirth-and-motherhood-lucy-jones/20398692Lucy's website - https://lucyfjones.com/Discover all of Lucy's books: https://lucyfjones.com/books/Lucy on Instagram - https://www.instagram.com/lucyfjones/Episode 333, An Honest Look Into Motherhood and Health - https://www.bossedup.org/podcast/episode333Episode 488, Talking Menopause at Work - https://www.bossedup.org/podcast/episode488Pregnancy leads to long-lasting changes in human brain structure, Nature Neuroscience - https://www.nature.com/articles/nn.4458The Birth Of A Mother by Alexandra Sacks - https://www.nytimes.com/2017/05/08/well/family/the-birth-of-a-mother.htmlOf Woman Born: Motherhood as Experience and Institution by Adrienne Rich - https://bookshop.org/p/books/of-woman-born-motherhood-as-experience-and-institution-adrienne-rich/8794956?ean=9780393541427LEVEL UP: a Leadership Accelerator for Women on the Rise - https://www.bossedup.org/levelupBossed Up Courage Community - https://www.facebook.com/groups/927776673968737/Bossed Up LinkedIn Group - https://www.linkedin.com/groups/7071888/

Ever feel like your body is working against you when it comes to weight loss? In this episode, I unpack the fascinating concept of homeostasis—our body's natural way of maintaining balance—and how it plays a critical role in our eating habits, cravings, and metabolism. I'll break down why extreme dieting backfires, how dopamine influences our food choices, and what we can do to work with our body instead of fighting against it. We'll also explore the power of pain—yes, pain!—and how embracing the right kind of discomfort can actually help us create lasting change. Drawing from the research of Dr. Anna Lembke, I'll share strategies to reset our brain's reward system, reduce emotional eating, and find balance in a world filled with instant gratification. And of course, I'll tie it all back to our Project Weight Loss journey and project management principles—because real, sustainable transformation is all about strategy and balance. If you've ever struggled with cravings, felt stuck in cycles of self-sabotage, or wondered why your body resists change, this episode is for you. Tune in as we uncover the science behind lasting weight loss and the small shifts that make all the difference. Quote of the week: “Balance is not something you find, it's something you create.” – by Jana KingsfordReferences:Caloric Restriction and Metabolic Adaptation: A study published in The American Journal of Clinical Nutrition found that increasing dietary protein from 15% to 30% of energy intake, while keeping carbohydrate intake constant, led to a sustained decrease in ad libitum caloric intake. Dopamine and Eating Behavior: Research in Nature Neuroscience highlighted that dopamine depletion reduces food-related reward activity, indicating that dopamine plays a significant role in eating behavior and energy balance.  Let's go, let's get it done. Get more information at: http://projectweightloss.org

Almost 2400 years ago, Hippocrates said "All disease begins in the gut"; and he was right. With modern scientific methods and studies to prove it, we can see exactly how and why all dieases begin in your gut, and what you can do to stop them. 93% od the leading causes of death are connected to your gut, and this episode is going to explain why that it, how it happens and to give you the tools you need to not only protect yourself and your loved ones, but even to reverse almost any diease.   TOPICS DISCUSSED: Reversing 93% of the leading causes of death The machanisms of how all diease begins in your gut How endotoxins (gut toxins) circulate around your body What they do to your organ systems and your body How to heal and seal your gut Reverse chronic inflammatory diseases How to heal from almost anything   Leave us a Review: https://www.reversablepod.com/review   Need help with your gut? Click the link, or visit gutsolution.ca for help: Get help now   Supplements: Get 15% off Practitioner Grade Supplements (forever) by creating an account   Contact us: reversablepod.com/tips    SOCIAL MEDIA: Instagram  Facebook  YouTube     STUDIES FOR REFERENCE: 1. LPS and Liver Disease: ·       Key Study: Lipopolysaccharides promote hepatic steatosis by activating the TLR4-NF-κB pathway in hepatocytes (Cai et al., 2012, Hepatology). Link: https://pubmed.ncbi.nlm.nih.gov/22025365/ 2. LPS and Kidney Disease: ·       Key Study: Role of lipopolysaccharide in the pathogenesis of kidney injury in sepsis (Matsushita et al., 2021, Nephrology). Link: https://pubmed.ncbi.nlm.nih.gov/33460487/ 3. LPS and Diabetes: ·       Key Study: Gut-derived endotoxin and metabolic inflammation in type 2 diabetes (Cani et al., 2007, Diabetologia). Link: https://pubmed.ncbi.nlm.nih.gov/17471239/ 4. LPS and Cancer: ·       Key Study: Gut microbiota-mediated inflammation in obesity: A link with gastrointestinal cancer (Cani et al., 2018, Nature Reviews Gastroenterology & Hepatology). Link: https://pubmed.ncbi.nlm.nih.gov/29348450/ 5. LPS and Cerebrovascular Disease: ·       Key Study: LPS-induced systemic inflammation exacerbates brain damage in ischemic stroke (Chen et al., 2016, Stroke). Link: https://pubmed.ncbi.nlm.nih.gov/26846899/ 6. LPS and Parkinson's Disease: ·       Key Study: Lipopolysaccharide induces neuroinflammation and dopaminergic neuron loss in Parkinson's disease models (Qin et al., 2007, Journal of Neuroscience). Link: https://pubmed.ncbi.nlm.nih.gov/17360907/ 7. LPS and Hypertension: ·       Key Study: Role of gut-derived endotoxemia in systemic inflammation and hypertension (Tang et al., 2017, Hypertension). Link: https://pubmed.ncbi.nlm.nih.gov/28209750/ 8. LPS and Colon/Gut Diseases: ·       Key Study: Lipopolysaccharides promote intestinal inflammation by disrupting the epithelial barrier (Schmidt et al., 2015, Gut). Link: https://pubmed.ncbi.nlm.nih.gov/25691570/ 9. Studies Supporting LPS's Role in Alzheimer's: ·       Study 1: Microbiome-derived lipopolysaccharide enriched in the perinuclear region of Alzheimer's disease brain (Zhao et al., 2017, Frontiers in Immunology). Link: https://pubmed.ncbi.nlm.nih.gov/28928740/ ·       Study 2: Lipopolysaccharides cause neuronal death and cognitive decline (Molecules, 2022). Link: https://pubmed.ncbi.nlm.nih.gov/35011994/ ·       Study 3: Neuroinflammation and Alzheimer's disease: Mechanisms of action (Nature Neuroscience, 2019). Link: https://pubmed.ncbi.nlm.nih.gov/30842661/

Como fatores ambientais e experiências de vida podem influenciar o nosso DNA, sem alterar sua sequência? Separe trinta minutinhos do seu dia e descubra, com a Mila Massuda, o que é epigenética e como esse fenômeno intrigante impacta a expressão gênica. Apresentação: Mila Massuda (@milamassuda) Roteiro: Mila Massuda (@milamassuda) e Emilio Garcia (@emilioblablalogia) Revisão de Roteiro: Vee Almeida Técnica de Gravação: Julianna Harsche (@juvisharsche) Editor: Angélica Peixoto (@angewlique) Mixagem e Masterização: Lívia Mello (@adiscolizard) Produção: Prof. Vítor Soares (@profvitorsoares), Matheus Herédia (@Matheus_Heredia) e BláBláLogia (@blablalogia) Gravado e editado nos estúdios TocaCast, do grupo Tocalivros (@tocalivros) REFERÊNCIAS ALBERTS, Bruce et al. Biologia molecular da célula. Artmed Editora, 2017. CAVALLI, G.; HEARD, E. Advances in epigenetics link genetics to the environment and disease. Nature, v. 571, n. 7766, p. 489–499, jul. 2019. COSTA, D. L.; YETTER, N.; DESOMER, H. Intergenerational transmission of paternal trauma among US Civil War ex-POWs. Proceedings of the National Academy of Sciences, v. 115, n. 44, p. 11215–11220, 15 out. 2018. DIAS, B. G.; RESSLER, K. J. Parental olfactory experience influences behavior and neural structure in subsequent generations. Nature Neuroscience, v. 17, n. 1, p. 89–96, 1 dez. 2013. KAATI, G.; BYGREN, L.; EDVINSSON, S. Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period. European Journal of Human Genetics, v. 10, n. 11, p. 682–688, 29 out. 2002.

Renzo Huber is a staff scientist at NIH. We talk about his work on layer-fMRI: what it  is, how Renzo got into it, how to do it, when it makes sense to do it, what the future holds, and much more.Support the show: https://geni.us/bjks-patreonTimestamps0:00:00: How Renzo got into high-resolution fMRI0:11:28: The difference between 3T and 7T fMRI0:22:46: Is a bigger fMRI scanner always better?0:33:35: Layer-fMRI0:56:28: For what types of research is layer-fMRI most useful?1:02:35: How to do layer-fMRI and make it reproducible1:19:21: The future of layer-fMRI1:27:02: A book or paper more people should read1:30:37: Something Renzo wishes he'd learnt sooner1:33:11: Advice for PhD students/postdocsPodcast linksWebsite: https://geni.us/bjks-podTwitter: https://geni.us/bjks-pod-twtRenzo's linksWebsite: https://geni.us/huber-webGoogle Scholar: https://geni.us/huber-scholarTwitter: https://geni.us/huber-twtBen's linksWebsite: https://geni.us/bjks-webGoogle Scholar: https://geni.us/bjks-scholarTwitter: https://geni.us/bjks-twtReferences and links mentionedEpisode with Peter Bandettini: https://geni.us/bjks-bandettiniEpisode with Emily Finn: https://geni.us/bjks-finnRenzo's blog about layer fMRI: https://layerfmri.com/YouTube channel on layer fMRI: https://www.youtube.com/@layerfmri/Bastos, ... & Friston (2012). Canonical microcircuits for predictive coding. Neuron.Bollmann & Barth (2021). New acquisition techniques and their prospects for the achievable resolution of fMRI. Progress in Neurobiology.Boulant, ... & Le Bihan (2024). In vivo imaging of the human brain with the Iseult 11.7-T MRI scanner. Nature Methods.Finn, ... & Bandettini (2019). Layer-dependent activity in human prefrontal cortex during working memory. Nature Neuroscience.Feynman (1985). "Surely you're joking, Mr. Feynman!": adventures of a curious character.Haarsma, Kok & Browning (2022). The promise of layer-specific neuroimaging for testing predictive coding theories of psychosis. Schizophrenia Research.Huber, ... & Bandettini (2017). High-resolution CBV-fMRI allows mapping of laminar activity and connectivity of cortical input and output in human M1. Neuron.Huber, ... & Möller (2019). Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2. Neuroimage.Huber, ... & Bandettini (2020). Sub-millimeter fMRI reveals multiple topographical digit representations that form action maps in human motor cortex. Neuroimage.Huber, ... & Kronbichler (2023). Evaluating the capabilities and challenges of layer-fMRI VASO at 3T. Aperture Neuro.Huber, ... & Horovitz (2023). Laminar VASO fMRI in focal hand dystonia patients. Dystonia.Persichetti, ... & Martin (2020). Layer-specific contributions to imagined and executed hand movements in human primary motor cortex. Current Biology.Polimeni, ... & Wald (2010). Laminar analysis of 7 T BOLD using an imposed spatial activation pattern in human V1. Neuroimage.

Motherhood is a journey full of transformations. We talk so much about how our bodies change, but what about our brains? In this episode, Dr Renee White chats with the incredible neuroscientist Dr. Magdalena Martínez García, who shares her groundbreaking research on how pregnancy and postpartum literally reshape the maternal brain.Dr. Magdalena, a postdoctoral researcher at UC Santa Barbara, has devoted her career to exploring the neuroscience of motherhood. Her work dives deep into how hormonal transitions during pregnancy and beyond affect our brains. Together, we unpack fascinating insights about brain remodeling, neuroplasticity, and the lasting impact of this incredible life stage.You'll Hear AboutThe Brain's Amazing Transformation: Discover how pregnancy rewires the brain, boosting areas responsible for social connection and caregiving.Labour's Lasting Impact: Whether vaginal or caesarean, labour plays a critical role in shaping the maternal brain.Healing Through Birth Stories: Talking about your birth experience isn't just cathartic; it helps you process and heal.Motherhood's Long-Term Effects: Explore how multiple pregnancies might influence your brain health down the track.Resources & Links:Books for Maternal Brain Insights:The Women's Brain Book by Sarah McKay, a fantastic resource from an Aussie author.Mummy Brain by Chelsea Conaboy, which unpacks the science of motherhood's brain changes.Neuromaternal by Susana Carmona (Spanish only for now), blending science with heartfelt stories.Must-Read Research:Studies from Nature Neuroscience that map brain changes during pregnancy, birth, and postpartum.Learn more about Dr Renee White and Explore Fill Your Cup Doula ServicesWant to be nurtured and nourished after the birth of your baby, have a peek at our doula offerings.If you want to gobble up our famous Chocolate + Goji lactation cookies, look no further!If this episode sparked something for you, share it with a friend or tag a mum who needs to hear it. Let's dive into the beautiful, messy, and powerful science behind motherhood together.Hit subscribe, and let's keep learning!Disclaimer: The information on this podcast presented by the Fill Your Cup is not a substitute for independent professional advice.Nothing contained in this podcast is intended to be used as medical advice and it is not intended to be used to diagnose, treat, cure or prevent any disease, nor should it be used for therapeutic purposes or as a substitute for your own health professional's advice.

Back in 2020, we released a two-part conversation (S1 Ep15 and 16) with neuroscientist Dr Lisa Feldman Barrett. We're long-time admirers of Lisa's work and were thrilled that she agreed to join co-hosts Jean Gomes and Scott Allender to discuss her work on The Evolving Leader podcast. It's also clear that Lisa Feldman Barrett's work is a big hit with our listeners as four years after release these two episodes continue to sit at the top of our listener chart, so here we've decided to pull them together into a special extended episode.Lisa Feldman Barrett is profoundly changing our understanding of the brain and in particular, our emotions. Since the ancient philosophers, and into our last century of scientific endeavour, emotions have been seen as hard-wired responses to external stimuli, located in specific regions of the brain. Lisa's work has over-turned this age-old model which shapes everything from our current beliefs about emotional intelligence to facial recognition software widely being deployed around the world.Beyond this extended conversation, you'll find more of Lisa Feldman Barrett's work in her two books, Seven and a Half Lessons About the Brain (2020) and How Emotions are Made (2017), as well as hundreds of peer reviewed scientific papers appearing in Science, Nature Neuroscience and other top journals in psychology and cognitive neuroscience.Other reading from Jean Gomes and Scott Allender:Leading In A Non-Linear World (J Gomes, 2023)The Enneagram of Emotional Intelligence (S Allender, 2023)Social:Instagram           @evolvingleaderLinkedIn             The Evolving Leader PodcastTwitter               @Evolving_LeaderYouTube           @evolvingleader The Evolving Leader is researched, written and presented by Jean Gomes and Scott Allender with production by Phil Kerby. It is an Outside production.Send a message to The Evolving Leader team

Want to add a healthy habit to your daily routine that is absolutely free and incredibly effective? Looking to reduce insulin resistance and lose visceral fat? Want to boost mental health and improve cognitive function? Look no further than walking! Tune in to hear us unpack the myriad of research-supported benefits.   In this episode, we discuss the incredible benefits of walking, from lowering blood pressure to improving heart rate variability to reducing stress and so much more. Learn about the magic number when it comes to step count, our thoughts on walking in nature vs. on a treadmill, and get practical tips for getting those steps!    Also in this episode:  Naturally Nourished Teas are buy 3 get 1 FREE, use code FREETEA Gift cards at Naturally Nourished Detox Masterclass 1/8 Keto Masterclass 1/15 Walking Pad C2 use code ALIMILLERRD for savings Health Benefits of Walking Lowers Blood Pressure Hypertension: Brisk walking for 30 minutes, five days a week reduces blood pressure (Hypertension, 2020). Improves Cholesterol Levels Cholesterol: Effects on LDL and HDL cholesterol (Journal of the American Heart Association, 2021). Lipid Profiles: Walking improves triglycerides and HDL (Atherosclerosis, 2021). Reduces the Risk of Coronary Artery Disease Coronary Artery Disease Risk: 150 minutes of walking weekly (Circulation, 2022). Enhances Cardiorespiratory Fitness Reduces Systemic Inflammation Systemic Inflammation: Walking lowers CRP and IL-6 (Arteriosclerosis, Thrombosis, and Vascular Biology, 2020). Systemic Inflammation: Walking reduces inflammatory cytokines (The Journal of Endocrinology, 2022). Helps Maintain Healthy Weight and Prevent Obesity Improves Heart Rate Variability Heart Rate Variability: HRV improvement with regular walking (Heart, 2022). Prevents Peripheral Artery Disease Peripheral Artery Disease: Walking improves circulation and function in PAD patients (Journal of Vascular Surgery, 2021). Reduces Resting Heart Rate Enhances Endothelial Function Supports Recovery After Cardiac Events Improves Insulin Sensitivity Insulin Sensitivity: Improvements with post-meal walks (Diabetes Care, 2021). Enhances Glucose Regulation Boosts Fat Oxidation Fat Oxidation: Brisk walking boosts fat metabolism (Journal of Applied Physiology, 2022). Reduces Visceral Fat Reduction of visceral fat after 10,000 steps/day (Obesity, 2021). Promotes Energy Balance Energy Balance: 12,000 steps/day for maintaining weight (Medicine & Science in Sports & Exercise, 2020). Regulates Hormones Related to Metabolism Increases Mitochondrial Efficiency Improves Metabolic Flexibility Prevents Metabolic Syndrome Helps Manage Type 2 Diabetes Mental health Stress Reduction: Nature walks lower cortisol more than treadmill (Environmental Research, 2022). Stimulates Neurogenesis and Brain Plasticity Brain Connectivity: Walking improves default mode network activity (Journal of Aging Research, 2021). Enhances Neurotransmitter Balance Supports Autonomic Nervous System Regulation Improves Sensory Integration Vestibular Function: Enhancing balance and stability with walking (Frontiers in Neuroscience, 2021). Strengthens Cognitive Function Neurogenesis and Cognitive Function: Exercise-induced brain growth (Nature Neuroscience, 2021). Promotes Myelination and Nerve Health Enhances Emotional Regulation via the Vagus Nerve Reduces Neurological Disease Risk Synchronizes the Nervous System Through Rhythmic Movement Improves Sleep and Circadian Rhythm Bone and Joint Health Immune System Support Longevity and Reduced Mortality Gut Health Gut Health: Positive effects on microbiota diversity (Gut Microbes, 2020). The Science of Step Counts Thoughts on Nature vs. Treadmill Walking Cognitive Benefits: Nature walking improves attention restoration (Nature Neuroscience, 2021). Proprioception: Benefits of uneven terrain in natural settings (Journal of Sports Medicine, 2023). Motivation: Outdoor walkers maintain habits better than treadmill users (Behavioral Medicine, 2022). Immune Boosting: Increased NK cell activity in forest walkers (International Journal of Environmental Health Research, 2021).   Sponsors for this episode:  According to extensive research by the Environmental Working Group, virtually every home in America has harmful contaminants in its tap water. That's why you've got to check out AquaTru. AquaTru purifiers use a 4-stage reverse osmosis purification process, and their countertop purifiers work with NO installation or plumbing. It removes 15x more contaminants than ordinary pitcher filters and are specifically designed to combat chemicals like PFAS in your water supply. Naturally Nourished Podcast listeners can use code ALIMILLERRD at AquaTru.com to save 20% off. 

Roberto Bottini is an Associate Professor at the University of Trento. We talk about his recent work on unusual cognitive maps in blind people, image spaces, metaphors, and he gives me some advice for writing successful grant applications.BJKS Podcast is a podcast about neuroscience, psychology, and anything vaguely related, hosted by Benjamin James Kuper-Smith.Support the show: https://geni.us/bjks-patreonTimestamps0:00:00: Roberto's background0:03:20: Start discussing Roberto's paper on altered grid cells in visually impaired people: theoretical background0:16:28: Methods & results: walking on a clock face / altered grid cells: fourfold symmetry0:47:48: Start discussing Roberto's paper on cognitive maps and image spaces (TiCS)0:52:05: Egocentric and allocentric perspectives0:55:27: Metaphors and analogies1:00:08: Tips for grant applications1:14:18: A book or paper that more people should read1:18:38: Something Roberto wishes he'd learnt sooner1:20:30: Advice for PhD students/postdocsPodcast linksWebsite: https://geni.us/bjks-podTwitter: https://geni.us/bjks-pod-twtRoberto's linksWebsite: https://geni.us/bottini-webGoogle Scholar: https://geni.us/bottini-scholarTwitter: https://geni.us/bottini-twtBen's linksWebsite: https://geni.us/bjks-webGoogle Scholar: https://geni.us/bjks-scholarTwitter: https://geni.us/bjks-twtReferencesAronov, ... & Tank (2017). Mapping of a non-spatial dimension by the hippocampal–entorhinal circuit. Nature.Bisiach & Luzzatti (1978). Unilateral neglect of representational space. Cortex.Bottini & Doeller (2020). Knowledge across reference frames: Cognitive maps and image spaces. Trends in Cognitive Sciences.Casasanto (2009). Embodiment of abstract concepts: good and bad in right-and left-handers. Journal of experimental psychology: General.Constantinescu, ... & Behrens (2016). Organizing conceptual knowledge in humans with a gridlike code. Science.Derdikman, ... & Moser (2009). Fragmentation of grid cell maps in a multicompartment environment. Nature neuroscience.Eichenbaum (2014). Time cells in the hippocampus: a new dimension for mapping memories. Nature Reviews Neuroscience.Gardenfors (2004). Conceptual spaces: The geometry of thought.Gentner (1983). Structure-mapping: A theoretical framework for analogy. Cognitive science.He & Brown (2019). Environmental barriers disrupt grid-like representations in humans during navigation. Current Biology.Horner, ... & Burgess (2016). Grid-like processing of imagined navigation. Current Biology.Jaynes (1976). The Origin of Consciousness in the Breakdown of the Bicameral Mind.Park, ... & Boorman (2021). Inferences on a multidimensional social hierarchy use a grid-like code. Nature Neuroscience.Sigismondi, ... & Bottini (2024). Altered grid-like coding in early blind people. Nature Communications.Stangl, ... & Wolbers (2018). Compromised grid-cell-like representations in old age as a key mechanism to explain age-related navigational deficits. Current Biology.Tolman (1948). Cognitive maps in rats and men. Psychological Review.Whittington, ... & Behrens (2022). How to build a cognitive map. Nature Neuroscience.

James (Mac) Shine is a PI and fellow at the University of Sydney. We talk about his background in sports, using fMRI to integrate various parts of neuroscience, collaboration, and much more.BJKS Podcast is a podcast about neuroscience, psychology, and anything vaguely related, hosted by Benjamin James Kuper-Smith.Support the show: https://geni.us/bjks-patreonTimestamps0:00:00: Mac's sporting background0:07:46: Overview of Mac's review in Nature (w/ Emily Finn and Russell Poldrack)0:14:03: The role of great editors in improving scientists and their work0:32:53: Connecting different levels of description0:40:07: Integration and specialisation0:48:49: You can scan any animal with fMRI - but they're usually anaesthetised0:54:13: The transfer from human fMRI to animal electrophysiology1:01:53: N=1 studies and layer-fMRI in clinical neuroscience1:16:17: Collaboration and building a multidisciplinary lab1:26:52: The magic formula in science: annoyance, excitement, and a constructive mindset1:34:51: Writing grants as a test to oneself, and the art of reframing1:41:52: A book or paper more people should read1:43:37: Something Mac wishes he'd learnt sooner1:45:43: Advice for PhD students/postdocsPodcast linksWebsite: https://geni.us/bjks-podTwitter: https://geni.us/bjks-pod-twtMac's linksWebsite: https://geni.us/shine-webGoogle Scholar: https://geni.us/shine-scholarTwitter: https://geni.us/shine-twtBen's linksWebsite: https://geni.us/bjks-webGoogle Scholar: https://geni.us/bjks-scholarTwitter: https://geni.us/bjks-twtReferences and linksOHMB interview: https://www.youtube.com/watch?v=ucDj_94ovaUBoyden, ... & Deisseroth (2005). Millisecond-timescale, genetically targeted optical control of neural activity. Nature Neuroscience.Finn, Poldrack & Shine (2023). Functional neuroimaging as a catalyst for integrated neuroscience. Nature.Friston, ... (2017). Active inference: a process theory. Neural Computation.Munn, ... Larkum & Shine (2023). A thalamocortical substrate for integrated information via critical synchronous bursting. PNAS.Newbold, ... & Dosenbach (2020). Plasticity and spontaneous activity pulses in disused human brain circuits. Neuron.Pezzulo & Cisek (2016). Navigating the affordance landscape: feedback control as a process model of behavior and cognition. TiCS.Poldrack, ... (2015). Long-term neural and physiological phenotyping of a single human. Nature Communications.Rao & Ballard (1999). Predictive coding in the visual cortex: a functional interpretation of some extra-classical receptive-field effects. Nature Neuroscience.Shine, ... (2011). Visual misperceptions and hallucinations in Parkinson's disease: dysfunction of attentional control networks?. Movement Disorders.Shine, ... & Poldrack (2016). The dynamics of functional brain networks: integrated network states during cognitive task performance. Neuron.Shine, ... & Poldrack (2016). Temporal metastates are associated with differential patterns of time-resolved connectivity, network topology, and attention. PNAS.Shine & Poldrack (2018). Principles of dynamic network reconfiguration across diverse brain states. NeuroImage.

When a brain scientist at the University of California, Irvine got pregnant at the age of 38, she saw a rare chance. Neuroscientist Liz Chrastil wanted to see how her brain changed while she was pregnant. 当加州大学欧文分校的一位脑科学家在 38 岁时怀孕时，她看到了一个难得的机会。神经科学家莉兹·克拉斯蒂尔想看看她怀孕期间大脑发生了怎样的变化。 Chrastil was among a group of researchers who presented their findings in a new study. It offers the first detailed map of one woman's brain through the steps of pregnancy, also called gestation. 克拉斯蒂尔是一组研究人员之一，他们在一项新研究中展示了他们的发现。它提供了第一个女性在怀孕（也称为妊娠）各个阶段的大脑详细图谱。Researchers say that motherhood affects nearly every part of the brain. 研究人员表示，母性几乎影响大脑的每个部分。 The researchers studied the effects of pregnancy in only one person: Chrastil. But their study has started a large international research project that aims to scan the brains of hundreds of women. The study could one day provide information about disorders like postpartum depression. Postpartum means after birth has taken place. 研究人员只研究了怀孕对一个人的影响：克里斯提尔。但他们的研究已经启动了一个大型国际研究项目，旨在扫描数百名女性的大脑。这项研究有一天可能会提供有关产后抑郁症等疾病的信息。产后是指出生后发生的。 Chrastil said it has been a very long process. “We did 26 scans before, during and after pregnancy…” She said some of the findings were very noteworthy, or in her words “remarkable.” Chrastil is co-writer of the study that researchers published in Nature Neuroscience in September. 克拉斯蒂尔表示，这是一个非常漫长的过程。“我们在怀孕前、怀孕期间和怀孕后进行了 26 次扫描……”她说，其中一些发现非常值得注意，或者用她的话来说“非常了不起”。Chrastil 是研究人员于 9 月份在《自然神经科学》杂志上发表的这项研究的合著者。 More than 80 percent of the parts of the brain studied had reductions in the amount of gray matter, where thinking takes place. This is an average of about four percent of the brain. This amount is nearly the same as the amount of reduction that happens during puberty. Puberty is the biological changes that cause a person to become a fertile adult. 研究中超过 80% 的大脑区域的灰质数量减少，灰质是进行思考的地方。这平均约为大脑的百分之四。这个量几乎与青春期期间发生的减少量相同。青春期是导致一个人成为具有生育能力的成年人的生物变化。 However, the researchers said the reduction is probably not a bad thing. It might mean that networks of interconnected nerve cells called “neural circuits” are preparing for a new time in a woman's life. 然而，研究人员表示，减少可能并不是一件坏事。这可能意味着被称为“神经回路”的相互连接的神经细胞网络正在为女性生命中的新时代做好准备。

Une équipe de chercheurs a réalisé une étude pionnière cartographiant les changements cérébraux chez une femme enceinte, de la préconception jusqu'à deux ans après l'accouchement. Cette recherche, publiée dans Nature Neuroscience, offre un aperçu sans précédent de la neuroplasticité maternelle pendant la grossesse. L'étude a suivi une femme primipare de 38 ans, effectuant 26 scans cérébraux et prélèvements sanguins sur une période de plus de deux ans. Les résultats révèlent des modifications significatives tant dans la matière grise que dans la matière blanche du cerveau. Les chercheurs ont observé une diminution prononcée du volume de matière grise et de l'épaisseur corticale dans l'ensemble du cerveau au fur et à mesure de la grossesse, coïncidant avec l'augmentation des hormones sexuelles. Ces changements étaient environ trois fois plus importants que la variabilité cérébrale moyenne chez les femmes non enceintes. Parallèlement, l'étude a mis en évidence une augmentation de l'intégrité microstructurale de la matière blanche, particulièrement marquée au deuxième trimestre, avant de revenir à la normale à la naissance. Cette découverte est une première dans le domaine. Contrairement aux idées reçues, la diminution du volume de matière grise n'est pas nécessairement négative. Les chercheurs suggèrent qu'il pourrait s'agir d'un "réglage fin" des circuits cérébraux en préparation à la parentalité, comparable aux changements observés pendant la puberté. Certaines régions cérébrales, comme le cortex extrastrié lié à la vision, sont restées stables. En revanche, le diencéphale ventral, comprenant des structures essentielles au comportement maternel, a montré les changements les plus prononcés. Ces modifications cérébrales ont persisté longtemps après l'accouchement, démontrant une capacité remarquable de neuroplasticité chez l'adulte. Cette découverte ouvre de nouvelles perspectives pour comprendre et potentiellement prédire des troubles comme la dépression post-partum. Bien que cette étude se soit concentrée sur une seule participante, elle fournit une carte détaillée du cerveau maternel pendant la grossesse. Ces données, disponibles en libre accès, offrent aux chercheurs une base pour explorer de nouvelles questions neurobiologiques et mieux comprendre le cerveau maternel. Les auteurs soulignent la nécessité de reproduire cette étude sur un échantillon plus large pour confirmer la généralisation de ces résultats. Néanmoins, cette recherche constitue une avancée majeure dans notre compréhension des changements cérébraux liés à la grossesse et ouvre la voie à de futures investigations sur la neurobiologie maternelle. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Une étude récente publiée dans Nature Neuroscience révèle un aspect fascinant du sommeil humain : notre cerveau connaît de brefs épisodes d'éveil même pendant les phases de sommeil profond. Ces "microréveils", trop courts pour être mémorisés, auraient en réalité des effets bénéfiques, notamment sur notre mémoire. Dirigée par la neurologue Celia Kjaerb de l'Université de Copenhague, cette recherche met en lumière le rôle crucial de la noradrénaline, une hormone proche de l'adrénaline. Cette substance, qui agit également comme neurotransmetteur, génère des micro-excitations cérébrales tout au long de la nuit. L'étude démontre que même lors d'un sommeil normal, notre cerveau se réveille plus d'une centaine de fois. Le niveau de noradrénaline dans le corps fluctue selon un cycle d'environ 30 secondes. Lorsque sa concentration est élevée, le cerveau connaît un bref éveil, tandis qu'il reste endormi quand le taux de l'hormone est au plus bas. Pour leurs expériences, les chercheurs ont équipé des souris de capteurs cérébraux et de fibres optiques microscopiques, permettant de mesurer avec précision leur activité cérébrale. Ils ont ainsi pu observer que ces microréveils, bien que trop courts pour être consciemment perçus, constituent une forme réelle d'éveil du point de vue scientifique. Ces épisodes d'éveil se produisent principalement durant les phases de sommeil liées à la mémoire. De façon surprenante, les chercheurs ont constaté que les souris présentant le plus grand nombre de micro-excitations démontraient de meilleures capacités de mémorisation. Dans le cadre de l'expérience, les rongeurs ont été exposés à deux objets différents avant de dormir. Au réveil, l'un des objets avait été remplacé. Les souris ayant les taux les plus élevés de noradrénaline ont montré une plus grande propension à explorer le nouvel objet, prouvant ainsi leur capacité à se souvenir de l'objet initial. Les chercheurs qualifient ce phénomène de "super mémoire". Ils suggèrent que la dynamique de la noradrénaline pourrait renforcer les processus du sommeil, affectant ainsi positivement la mémoire non seulement chez les rongeurs, mais potentiellement chez tous les mammifères, y compris les humains. Cette découverte ouvre de nouvelles perspectives dans la compréhension des mécanismes du sommeil et de son impact sur nos fonctions cognitives. Elle souligne l'importance de ces cycles naturels d'éveil et de sommeil profond pour la consolidation de notre mémoire. Bien que ces microréveils puissent sembler perturbateurs à première vue, ils apparaissent en réalité comme un élément essentiel d'un sommeil réparateur et bénéfique pour notre cerveau. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Neuroscientist Dr. Liz Chrastil joins Lisa Dent to discuss what pregnancy does to a mother’s brain. Dr. Chrastil explains that after her 26 brain scans, key areas in her cortex shrank and thinned then remained that way long-term. You can find the proof-of-concept experiment in the journal Nature Neuroscience.

Die Themen in den Wissensnachrichten: +++ Hunde helfen gegen Schmerzen +++ Todesfälle durch Antibiotika-Resistenzen könnten sich bis 2050 verdoppeln +++ Richtig schwere Fragen gesucht, um Grenzen von KI zu testen +++**********Weiterführende Quellen zu dieser Folge:Pet dogs succeed where human companions fail: The presence of pet dogs reduces pain/ Acta Psycholgica, September 2024Global burden of antimicrobial resistance and forecasts to 2050/ The Lancet, 16.09.2024Neuroanatomical changes observed over the course of a human pregnancy/ Nature Neuroscience, 16.09.2024Submit Your Toughest Questions for Humanity's Last Exam/ Scale, 16.09.2024Thread form at the Crystal Palace/ The International Journal for the History of Engineering & Technology, 03.09.2024Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: Tiktok und Instagram.

Un nuevo estudio publicado en la revista Nature Neuroscience describe los cambios en el cerebro de una mujer durante y después del embarazo, entre otros una disminución “pronunciada” del volumen de materia gris y del grosor cortical. Susana Carmona Cañabate, investigadora principal del Grupo Neuromaternal del Instituto de Investigación Sanitaria Gregorio Marañón, explica las conclusiones de este nuevo trabajo realizado en California, y contextualiza con sus propios trabajos relacionados con los cambios que la maternidad produce a todos los niveles.

Un nuevo estudio publicado en la revista Nature Neuroscience describe los cambios en el cerebro de una mujer durante y después del embarazo, entre otros una disminución “pronunciada” del volumen de materia gris y del grosor cortical. Susana Carmona Cañabate, investigadora principal del Grupo Neuromaternal del Instituto de Investigación Sanitaria Gregorio Marañón, explica las conclusiones de este nuevo trabajo realizado en California, y contextualiza con sus propios trabajos relacionados con los cambios que la maternidad produce a todos los niveles.

Die Themen in den Wissensnachrichten: +++ Neue Fossilien von indonesischen "Hobbits" entdeckt +++ ChatGPT ist genau so schlecht wie Dr. Google +++ Darmgesundheit von Fohlen entscheidet über den sportlichen Erfolg von Rennpferden +++ **********Weiterführende Quellen zu dieser Folge:Early evolution of small body size in Homo floresiensis, Nature Communications, 06.08.2024Evaluation of ChatGPT as a diagnostic tool for medical learners and clinicians, PLOS ONE, 31.07.2024Early-life gut bacterial community structure predicts disease risk and athletic performance in horses bred for racing, Scientific Reports, 07.08.2024Orexin neurons mediate temptation-resistant voluntary exercise, Nature Neuroscience, 06.08.2024Convergent and adaptive evolution drove change of secondary cell wall ultrastructure in extant lineages of seed plants, New Phytologist, 30.07.2024Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: Tiktok und Instagram.

This short comes from a two part conversation that co-hosts Jean Gomes and Scott Allender had with Dr Lisa Feldman Barrett back in December 2020 (S1 Ep15 and 16). LISTEN TO THE ENTIRE CONVERSATION:How emotions are made with Lisa Feldman Barrett (Pt 1)How emotions are made with Lisa Feldman Barrett (Pt 2)Lisa Feldman Barrett is among the top 0.1% most cited scientists in the world for her revolutionary research in psychology and neuroscience. Distinguished Professor of Psychology at Northeastern University, and Chief Science Officer for the Center for Law, Brain and Behaviour at Harvard, Lisa Feldman Barrett, is profoundly changing our understanding of the brain and in particular, our emotions. Since the ancient philosophers, and into our last century of scientific endeavor, emotions have been seen as hard-wired responses to external stimuli, located in specific regions of the brain. Lisa's work has over-turned this age-old model which shapes everything from our current beliefs about emotional intelligence to facial recognition software widely being deployed around the world.  Lisa Feldman Barrett has written two books, Seven and a Half Lessons About the Brain (2020) and How Emotions are Made (2017), as well as hundreds of peer reviewed scientific papers appearing in Science, Nature Neuroscience and other top journals in psychology and cognitive neuroscience.Social:Instagram           @evolvingleaderLinkedIn             The Evolving Leader PodcastTwitter               @Evolving_LeaderYouTube           @evolvingleader The Evolving Leader is researched, written and presented by Jean Gomes and Scott Allender with production by Phil Kerby. It is an Outside production.Send a message to The Evolving Leader team

Durante el embarazo, el cuerpo de la mujer sufre transformaciones evidentes: el útero se expande para alojar al feto en crecimiento, y los senos aumentan de tamaño en preparación para la lactancia, ciertas hormonas se disparan y aparecen náuseas, fatiga y cambios en el apetito y las emociones. La ansiedad y la preocupación sobre la salud del bebé, el parto y la futura maternidad son comunes. Esos son cambios evidentes, pero existen muchos otros que no son visibles y afectan al cerebro. Estudios recientes revelan que el cerebro de las madres primerizas sufre disminuciones prominentes en el volumen de materia gris inducidas por el embarazo. Un artículo recientemente publicado en Nature Neuroscience, cuya primera autora es Magdalena Martínez García, antes investigadora en el Instituto de Investigación Sanitaria Gregorio Marañón de Madrid y ahora en la Universidad de California, Santa Bárbara, revela que la neurociencia ha ignorado en gran medida los cuerpos de las mujeres y propone formas de llenar las lagunas de conocimiento que existen en este campo.

Durante el embarazo, el cuerpo de la mujer sufre transformaciones evidentes: el útero se expande para alojar al feto en crecimiento, y los senos aumentan de tamaño en preparación para la lactancia, ciertas hormonas se disparan y aparecen náuseas, fatiga y cambios en el apetito y las emociones. La ansiedad y la preocupación sobre la salud del bebé, el parto y la futura maternidad son comunes. Esos son cambios evidentes, pero existen muchos otros que no son visibles y afectan al cerebro. Estudios recientes revelan que el cerebro de las madres primerizas sufre disminuciones prominentes en el volumen de materia gris inducidas por el embarazo. Un artículo recientemente publicado en Nature Neuroscience, cuya primera autora es Magdalena Martínez García, antes investigadora en el Instituto de Investigación Sanitaria Gregorio Marañón de Madrid y ahora en la Universidad de California, Santa Bárbara, revela que la neurociencia ha ignorado en gran medida los cuerpos de las mujeres y propone formas de llenar las lagunas de conocimiento que existen en este campo.

How can we decode the meaning of the speech we hear or imagine? In this episode of the Neurocareers Podcast BCI Award series, we explore the groundbreaking work of Jerry Tang and a team of colleagues from Dr. Alexander Huths's Lab, a nominee for the International BCI Award. His research, published in Nature Neuroscience, introduces a non-invasive brain-computer interface (BCI) that can decode continuous language from functional magnetic resonance imaging (fMRI). This innovative decoder can interpret the meaning of perceived speech, imagined speech, and even silent videos, showcasing a significant leap forward in BCI technology. Jerry's work demonstrates that continuous language can be decoded from multiple brain regions by recording cortical semantic representations. Jerry discusses mental privacy in BCI applications. Join us as Jerry Tang shares insights from his BCI Award-nominated project, his career journey, and valuable advice for aspiring scientists and those aiming to succeed in their BCI Award submissions. Whether you're fascinated by neuroscience, intrigued by BCI technology, or looking for inspiration in your career, this episode is packed with valuable knowledge and insights. The International BCI Award is back and bigger than ever! If you're working on pioneering BCI research, don't miss your chance to gain international recognition. With a total endowment of $6,000 USD and opportunities to publish and present your work globally, this is an opportunity to shine at the forefront of neuroscience innovation. For more details on submission and criteria, visit BCI Award Submission Information: https://www.bci-award.com/Home Tune in to discover how Jerry Tang is breaking new ground in decoding the human brain!   About the Podcat Guest: Jerry Tang is a Ph.D. student in Computer Science at UT Austin, working with Alex Huth. His research focuses on modeling and decoding brain responses during language processing and understanding how language relates to other cognitive processes, such as vision. The link to the article in Nature Neuroscience: https://www.nature.com/articles/s41593-023-01304-9 Learn more about the HuthLab at the University of Texas in Austin: https://www.cs.utexas.edu/~huth/index.html   About the Podcat Host: The Neurocareers podcast is brought to you by The Institute of Neuroapproaches (https://www.neuroapproaches.org/) and its founder, Milena Korostenskaja, Ph.D. (Dr. K), a neuroscience educator, research consultant, and career coach for people in neuroscience and neurotechnologies. As a professional coach with a background in the field, Dr. K understands the unique challenges and opportunities job applicants face in this field and can provide personalized coaching and support to help you succeed. Here's what you'll get with one-on-one coaching sessions from Dr. K: Identification and pursuit of career goals Guidance on job search strategies, resume, and cover letter development Neurotech / neuroscience job interview preparation and practice Networking strategies to connect with professionals in the field of neuroscience and neurotechnologies Ongoing support and guidance to help you stay on track and achieve your goals You can always schedule a free neurocareer consultation/coaching session with Dr. K at https://neuroapproaches.as.me/free-neurocareer-consultation Subscribe to our Nerocareers Newsletter to stay on top of all our cool neurocareers news at updates https://www.neuroapproaches.org/neurocareers-news

Trauma transgeneracyjna… kit, czy coś, co faktycznie waży na naszym funkcjonowaniu? Nie znam się na biologicznych mechanizmach na tyle, aby być tu głosem eksperckim. Zatem zamiast głosić magiczne treści, zapraszam do rozmowy wybitnego specjalistę w tej dziedzinie, lekarza i naukowca, autora publikacji w takich czasopismach jak Nature czy Science, przed Wami rozmowa z dr Ali Jawaid.Ten odcinek nie powstałby bez wsparcia Patronów i Patronek.Podcast realizowany jest w języku angielskim, ale tłumaczenie rozmowy znajdziecie na moim blogu www.joannagutral.pl (jeśli nie już, to będzie lada moment!)  – bierzcie i ślijcie w świat, bo wierzę, że rozumienie jest ważne w życiu bardzo. Zapraszam do wysłuchania rozmowy.Fot. moje @opowiedziane_swiatlemGość:Dr Ali Jawaid -  lekarz i naukowiec o wykształceniu zarówno klinicznym, jak i neurologicznym. Ukończył studia medyczne na Uniwersytecie Aga Khan w Karachi, w Pakistanie, a następnie odbył staż w zakresie neuropsychiatrii na Baylor College of Medicine w Houston, TX, USA. Następnie ukończył studia doktoranckie (MD-PhD) w dziedzinie neurologii w Szwajcarii. Obecnie dr Ali Jawaid jest kierownikiem Pracowni Badań Translacyjnych w Chorobach Neuropsychiatrycznych (TREND Lab) w Instytucie Nenckiego w Warszawie. Dr Jawaid pracował intensywnie w dziedzinach traumy dzieciństwa, pamięci, zaburzeń neurodegeneracyjnych, neuroepigenetyki i dziedziczenia epigenetycznego. Jest autorem ponad 75 publikacji w znaczących czasopismach naukowych, takich jak Nature, Science, Nature Neuroscience, Nature Human Behavior, Neuron, Nature Communications, Trends in Genetics, EMBO Journal i Molecular Neurodegeneration (h-index=29). Obecnie jest stypendystą FENS-Kavli Network of Excellence, platformy 30 najwybitniejszych neurologów w Europie w ciągu 15 lat od uzyskania doktoratu. Poza pracą naukową jest autorem fikcji, poetą i entuzjastą wirtualnej rzeczywistości.Montaż: Eugeniusz Karlov

In this episode of the Epigenetics Podcast, we talked with Sarah Marzi from the UK Dementia Research Institute at Imperial College London about her work on epigenetic changes in Alzheimer's Disease, and comparing CUT&Tag to ENCODE ChIP-Seq using limited cell samples. The interview discusses Sarah Marzi's work on ChIP-Seq experiments and their significance in understanding Alzheimer's disease from an epigenetic perspective. The discussion touches on the widespread dysregulation and changes in acetylation, particularly in genes associated with Alzheimer's risk, providing insights into potential links between epigenetic insults and disease onset. Moving on to the technical aspects of the study, the interview examines the strategic use of CUT&Tag. It explores the challenges and optimizations involved in accurately profiling limited cell samples. The dialogue also compares CUT&Tag to ENCODE ChIP-Seq, highlighting the complexities of peak calling and data interpretation across different methodologies.   References Kumsta, R., Marzi, S., Viana, J. et al. Severe psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1. Transl Psychiatry 6, e830 (2016). https://doi.org/10.1038/tp.2016.95 Marzi, S. J., Schilder, B. M., Nott, A., Frigerio, C. S., Willaime‐Morawek, S., Bucholc, M., Hanger, D. P., James, C., Lewis, P. A., Lourida, I., Noble, W., Rodriguez‐Algarra, F., Sharif, J., Tsalenchuk, M., Winchester, L. M., Yaman, Ü., Yao, Z., The Deep Dementia Phenotyping (DEMON) Network, Ranson, J. M., & Llewellyn, D. J. (2023). Artificial intelligence for neurodegenerative experimental models. Alzheimer's & Dementia, 19(12), 5970–5987. https://doi.org/10.1002/alz.13479 Marzi, S. J., Leung, S. K., Ribarska, T., Hannon, E., Smith, A. R., Pishva, E., Poschmann, J., Moore, K., Troakes, C., Al-Sarraj, S., Beck, S., Newman, S., Lunnon, K., Schalkwyk, L. C., & Mill, J. (2018). A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience, 21(11), 1618–1627. https://doi.org/10.1038/s41593-018-0253-7 Hu, D., Abbasova, L., Schilder, B. M., Nott, A., Skene, N. G., & Marzi, S. J. (2022). CUT&Tag recovers up to half of ENCODE ChIP-seq peaks in modifications of H3K27 [Preprint]. Genomics. https://doi.org/10.1101/2022.03.30.486382   Related Episodes When is a Peak a Peak? (Claudio Cantù) Development of Integrative Machine Learning Tools for Neurodegenerative Diseases (Enrico Glaab) DNA Methylation Alterations in Neurodegenerative Diseases (Paula Desplats)   Contact Epigenetics Podcast on X Epigenetics Podcast on Instagram Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Epigenetics Podcast on Threads Active Motif on X Active Motif on LinkedIn Email: podcast@activemotif.com

Dora Hermes and Kai Miller are associate professors at Mayo Clinic, where they have become a powerhouse on neuroscience, due to their strong collaboration and work in neural signal processing and analysis. Dora has a mathematics background, while Kai studied physics, including a PhD in physics, before becoming a functional neurosurgeon. Last year, both of them last authored a paper each at Nature Neuroscience, each with remarkable and groundbreaking findings about pretty different topics. The first paper dove into the organization of the primary motor cortex using invasive electrophysiological recordings in humans. The second measured conduction delays along fiber tracts in the developing brain.We hope you enjoy this conversation as much as we did!

It's incredible how dramatic climate science can be. That was my first thought after I watched the new documentary, Canary, which chronicles the life and career of Dr. Lonnie Thompson. This week, the subject behind the film, Dr. Thompson, and the co-directors of the documentary, Danny O'Malley and Dr. Alex Rivest, explain how the film came together and the thrilling story behind its development. We discuss how to tell compelling climate stories, what motivates their work, and what decades of glacier science can teach us about the climate crisis.   Lonnie G. Thompson, a Distinguished University Professor at The Ohio State University, and senior research scientist, specializes in paleoclimatology, ice cores, and climate change.  Alex Rivest is a Massachusetts Institute of Technology-trained PhD Neuroscientist. Having worked alongside Nobel Prize winner Dr. Susumu Tonegawa, his research has been published in two of the most highly renowned scientific journals, Science and Nature Neuroscience.  Danny O'Malley is a Grammy nominated and James Beard nominated film director. Best known for his work on Netflix's Chef's Table, where he serves as co-executive producer and a director. As always, follow us @climatepod on Twitter and email us at theclimatepod@gmail.com. Our music is "Gotta Get Up" by The Passion Hifi, check out his music at thepassionhifi.com. Rate, review and subscribe to this podcast on iTunes, Spotify, Stitcher, and more! Subscribe to our YouTube channel! Join our Facebook group.   Rent Canary

Imagine being trapped in your own body, unable to move or communicate effectively. This may seem like a nightmare, but it is a reality for many people living with brain or spinal cord injuries. Join us as we talk with Jaimie Henderson, a Stanford neurosurgeon leading groundbreaking research in brain-machine interfaces. Henderson shares how multiple types of brain implants are currently being developed to treat neurological disorders and restore communication for those who have lost the ability to speak.  We also discuss the legacy of the late Krishna Shenoy and his transformative work in this field. Learn moreHenderson's Neural Prosthetics Translational LabBrainGate Consortium – "Turning thought into action"Commentary on Neuralink's brain-interfacing technology by Wu Tsai Neurosciences Institute Faculty Scholar Paul Nuyujukian (WIRED, 2023; NBC Bay Area, 2024)Brain Implants Helped 5 People Recover From Traumatic Injuries (New York Times, 2023)Related publication: Nature Medicine, 2023Brain to text technology is about more than Musk (Washington Post, 2023)Related publication: Nature, 2023The man who controls computers with his mind (New York Times Magazine, 2022)Software turns ‘mental handwriting' into on-screen words, sentences (Stanford Medicine, 2021)Related video: Wu Tsai Neurosciences Institute, 2021Related publication: Nature, 2021Learn about the work of the late Krishna ShenoyKrishna V. Shenoy (1968–2023) (Nature Neuroscience, 2023)Krishna Shenoy, engineer who reimagined how the brain makes the body move, dies at 54 (Stanford Engineering, 2023)Using software engineering to bring back speech in ALS (Wu Tsai Neurosciences Institute, 2023)Episode CreditsThis episode was produced by Michael Osborne, with production assistance by Morgan Honaker, and hosted by Nicholas Weiler. Cover art by Aimee Garza.Thanks for listening! Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Award-winning dementia researcher and educator Dr. Nir Grossman joins Being Patient Live Talks to talk about the potential of cutting-edge medical technology like deep brain stimulation as an emerging approach to treating neurodegenerative diseases like Alzheimer's. Grossman is an associate professor at the Department of Brain Sciences at Imperial College London and a founding fellow of the UK Dementia Research Institute (UK-DRI). He received a prestigious prize from the Science Journal and American Association for the Advancement of Science (AAAS) for developing a new, non-invasive method of deep brain stimulation, called temporal interference, which is now in early clinical trials. Previously, this procedure required invasive brain surgery. His research has been published in scientific journals like Cell, Science, and Nature Neuroscience. Read the article here: https://www.beingpatient.com/nir-grossman-deep-brain-stimulation-dementia/ ___ If you loved watching this Live Talk, visit our website to find more of our Alzheimer's coverage and subscribe to our newsletter: https://www.beingpatient.com/ Follow Being Patient: Twitter: https://twitter.com/Being_Patient_ Instagram: https://www.instagram.com/beingpatientvoices/ Facebook: https://www.facebook.com/beingpatientalzheimers LinkedIn: https://www.linkedin.com/company/being-patient Being Patient is an editorially independent journalism outlet for news and reporting about brain health, cognitive science, and neurodegenerative diseases. In our Live Talk series on Facebook, former Wall Street Journal Editor and founder of Being Patient, Deborah Kan, interviews brain health experts and people living with dementia. Check out our latest Live Talks: https://www.beingpatient.com/category/video/ #DeepBrainStimulation #Neuromodulation #AlzheimersResearch #Dementia #Alzheimers

Award-winning dementia researcher and educator Dr. Nir Grossman joins Being Patient Live Talks to talk about the potential of cutting-edge medical technology like deep brain stimulation as an emerging approach to treating neurodegenerative diseases like Alzheimer's. Grossman is an associate professor at the Department of Brain Sciences at Imperial College London and a founding fellow of the UK Dementia Research Institute (UK-DRI). He received a prestigious prize from the Science Journal and American Association for the Advancement of Science (AAAS) for developing a new, non-invasive method of deep brain stimulation, called temporal interference, which is now in early clinical trials. Previously, this procedure required invasive brain surgery. His research has been published in scientific journals like Cell, Science, and Nature Neuroscience. Read the article here: https://www.beingpatient.com/nir-grossman-deep-brain-stimulation-dementia/ ___ If you loved watching this Live Talk, visit our website to find more of our Alzheimer's coverage and subscribe to our newsletter: https://www.beingpatient.com/ Follow Being Patient: Twitter: https://twitter.com/Being_Patient_ Instagram: https://www.instagram.com/beingpatientvoices/ Facebook: https://www.facebook.com/beingpatientalzheimers LinkedIn: https://www.linkedin.com/company/being-patient Being Patient is an editorially independent journalism outlet for news and reporting about brain health, cognitive science, and neurodegenerative diseases. In our Live Talk series on Facebook, former Wall Street Journal Editor and founder of Being Patient, Deborah Kan, interviews brain health experts and people living with dementia. Check out our latest Live Talks: https://www.beingpatient.com/category/video/ #DeepBrainStimulation #Neuromodulation #AlzheimersResearch #Dementia #Alzheimers

*** How history's largest ape met its end *** For nearly two million years, a gigantic ape, three meters tall and weighing a quarter of a tonne, lived in what is now southern China, before mysteriously disappearing. Exactly why the Gigantopithecus Blacki went extinct has been a huge mystery for paleontologists, especially because other apes were able to thrive at the time. Now a massive study, co-led by geochronologist Kira Westaway of Macquarie University, reveals their size was a disadvantage, and left them unable to adapt to a changing climate. The research was published in the journal Nature. *** People with PTSD process their trauma as if it's happening in the present *** Post traumatic stress disorder (PTSD) is characterized by intrusive thoughts that cause people to relive their trauma. In a new study in the journal Nature Neuroscience, scientists have figured out that this is reflected in brain activity. Daniela Schiller, a professor of neuroscience and psychiatry at the Icahn School of Medicine at Mount Sinai in New York, said their brains respond differently with traumatic memories than with ordinary memories, causing the traumatic memories to feel as if they are happening in the present, rather than the past. *** Paleontologists identify animal skin 4½ times older than the last dinosaurs *** A fossilised skin sample discovered in an Oklahoma cave is the oldest skin sample ever identified. It belonged to a reptile species that lived nearly 300 million years ago. Ethan Mooney, a paleontology masters student at the University of Toronto, said this skin fossil gives insight into how the first vertebrate animals adapted to a more protective with the critical transition from ocean to land. Their research was published in the journal Current Biology. *** How an octopus told us the West Antarctic ice sheet collapsed *** Scientists are trying to learn when the West Antarctic Ice Sheet last collapsed, in order to learn when it might happen again. In a new study, published in the journal Science, Sally Lau at James Cook University analyzed the DNA of Turquet's octopuses, which have been scuttling around the Antarctic sea floor for millions of years. These octopuses are today separated by massive ice sheets, but by looking at when different populations were able to breed throughout history, they could see when the ice wasn't there. *** Geologic Hydrogen could be clean, green and plentiful *** More than a century ago we discovered that there were rich deposits of energy buried deep in Earth, and so oil and gas became the foundation of our industrial civilization. Now history might be repeating itself as scientists think there could be massive amounts of clean, green hydrogen hiding underground as well. Quirks producer Jim Lebans spoke with Geochemist Barbara Sherwood Lollar from the University of Toronto, and geologist Geoffrey Ellis from the United States Geological Survey to understand where this hydrogen has come from, how much there is, and what its potential could be as an energy resource.

This episode  covers various stages of a dog's life and corresponding physical and psychological changes that come with each stage. The conversation aims to provide insight, prepare you to help your dog through difficult times, to manage behavior, and plan fundamental training for your furry friend. When your dog displays sudden or concerning behavior at any stage of their life, or if any changes continue without resolution, please contact your veterinarian first for guidance. Thanks for listing vivian@dogbehaviorandconsulting.comEMBARK DNA savingsStarting December19 and through December 28,  Save $60 off Breed + Health Test & Purebred Test, Save $30 off Breed ID Test Click on this link here . At check out use the code DNAYAYResourcesAsher, L., England, G. C., Sommerville, R., & Harvey, N. D. (2020). Teenage dogs? Evidence for adolescent-phase conflict behaviour and an association between attachment to humans and pubertal timing in the domestic dog. Biology letters, 16(5), 20200097.de Faria Jr, O., Pivonkova, H., Varga, B., Timmler, S., Evans, K. A., & Káradóttir, R. T. (2021). Periods of synchronized myelin changes shape brain function and plasticity. Nature Neuroscience, 24(11), 1508-1521.Dinwoodie, I. R., Zottola, V., & Dodman, N. H. (2021). An investigation into the impact of pre-adolescent training on canine behavior. Animals, 11(5), 1298.Houston, M. L. (1968). The early brain development of the dog. Journal of Comparative Neurology, 134(3), 371-383.Miklósi, Á. (2014). Dog behaviour, evolution, and cognition. oUp Oxford.Overall, K. (2013). Manual of Clinical Behavioral Medicine for Dogs and Cats-E-Book. Elsevier Health Sciences.Owczarczak-Garstecka, S. C., Da Costa, R. E., Harvey, N. D., Giragosian, K., Kinsman, R. H., Casey, R. A., ... & Murray, J. K. “It's Like Living with a Sassy Teenager!”: A Mixed-Methods Analysis of Dog Owners' Perceptions and Experiences of Dog Behaviour between the Ages of 12 Weeks and 2 Years.Scott, J. P., & Fuller, J. L. (2012). Genetics and the Social Behavior of the Dog (Vol. 570). University of Chicago Sapolsky, R. M. (2005). Why Zebras Don't Get Ulcers. Henry Holt & Company: New York, NY, USA.Serpell, J., Duffy, D. L., & Jagoe, J. A. (2016). Becoming a dog: Early experience and the development of behavior. The domestic dog: Its evolution, behavior and interactions with People, 2, 93-117.Acoustic morning leaves TunePocket Receive $50 off when you follow this link and enter CSAT50 at check out. Here's the link written out https://courses.malenademartini.com/?aff=4 This podcast is suitable for pet dog guardians, shelters, rescue staff/volunteer fosters, adopters, veterinary professionals, animal trainers, behaviorists, research scientists and anyone interested in learning about human dog relations, evidence based behavior interventions, and ethical and humane practices. All content provided on this podcast is for entertainment and educational purposes only. The podcast host makes no representations as to the accuracy or completeness of any information; is not liable for any errors or omissions in the information; will not be liable for any losses, injuries or damages from the display or use of information. All information provided is not intended to diagnose, cure or prevent any conditions. Listening to this podcast does not guarantee change. Contact your veterinarian or board certified behaviorist if behavior persists.

When most of us think about dopamine, we think about reward signals. But new research from Northwestern Medicine, published in Nature Neuroscience, has found a genetic subtype of dopamine neurons that do not respond to rewards at all, and instead, fire when the body moves. Rajeshwar Awatramani, PhD, and Daniel Dombeck, PhD led this work. In this episode they explain how the results could change the field of dopamine research

Our guest today is Dr. Lisa Feldman Barrett. Lisa is among the top 0.1% most cited scientists in the world for her revolutionary research in psychology and neuroscience. She is a University Distinguished Professor of Psychology at Northeastern University. She also holds appointments at Harvard Medical School and Massachusetts General Hospital, where she is Chief Science Officer for the Center for Law, Brain & Behavior. In addition to the books Seven and a Half Lessons About the Brain and How Emotions are Made, Dr. Barrett has published over 275 peer-reviewed, scientific papers appearing in Science, Nature Neuroscience, and other top journals in psychology and cognitive neuroscience, as well as six academic volumes published by Guilford Press. She writes regularly about science in the popular press, including The New York Times, The Guardian, Scientific American, BBC Science Focus, Time magazine and more. She also has a popular TED talk, which we have linked in her bio, that has been viewed over 6.5 million times. Dr. Barrett received a National Institutes of Health Director's Pioneer Award for her revolutionary research on emotion in the brain. These highly competitive, multimillion dollar awards are given to scientists of exceptional creativity who are expected to transform biomedical and behavioral research.  Among her many accomplishments, Dr. Barrett has testified before Congress, presented her research to the FBI, consulted to the National Cancer Institute, and been a featured guest on public television and podcast and radio programs worldwide. She recently did a 2 hour podcast with Andrew Huberman which is definitely worth checking out! She was president of the Association for Psychological Science in 2019–2020 and co-founded the Society for Affective Science. She is also an elected fellow of the American Academy of Arts & Sciences and the Royal Society of Canada. Todays Topics: Her personal/professional story.  How she became THE person who would teach the world how emotions are REALLY made. How emotions are made (they aren't simply triggered reactions). She walks us through an instance of emotion (sadness, anxiety).  Her thoughts on adverse childhood experiences/trauma and disordered eating How metabolic functioning effects everything and why we need to be aware when we are doing things that are metabolically expensive (uncertainty, neural processing). How people predict and experience pain It's not our thoughts that create feelings but feelings that create our thoughts.  How our brain writes a story that makes predictions about what will happen and this becomes our reality.  Can we teach our brains to make different predictions? How emotion concepts are taught to us by our parents Actionable tools listeners can use to manage their body budget.  What is next for her? If she could tell a younger version of yourself something about emotions, what she would tell herself? Follow Lisa: Ted Talk: https://lisafeldmanbarrett.com/multimedia/ Books: https://lisafeldmanbarrett.com/books/ Website: https://lisafeldmanbarrett.com    

The Society for Neuroscience annual meeting, a big conference in neuroscience, is about to start. This year, it's in Washington. And here is a sneak peek of the meeting for you. Along with editors at Springer Nature, I got the chance to ask a bit about the meeting before it starts shortly. It was a mash up of a press conference of sorts and a wider discussion with colleagues from Scientific American and from Nature Neuroscience. In this podcast episode, you will hear questions from them and from me and responses by Dr. Oswald Steward, the president of the Society for Neuroscience (SFN) and Dr. Damien Fair who is the chair of the SfN Public Education and Communication committee. (Art J. Jackson) (Music: Billiard Balls by Raw, licensed from artlist.io)

Welcome to the Psychedelic Science conference in Denver, Colorado! In this episode, we delve into Daniel's background and his pivotal role at 'HMNC Brain Health'. We explore the mission and values of HMNC Brain Health, the origins of the company, and gain insight into the hypothalamus-pituitary-adrenal axis. We also discuss potential pharmacotherapy solutions for depression, the benefits that artificial intelligence may bring to therapy in the future, treatment-resistant patients, and HMNC's distinctive ketamine program. Additionally, we touch upon the skepticism faced by psychedelic therapies in European countries, Daniel's upcoming projects, and much more! 00:00 - Introduction 01:20 - The Founding Of HMNC 02:13 - Daniel's Role At HMNC Brain Health 04:16 - What HMNC Stand For, The HPA Axis 06:41 - Treatment-Resistant Patients 09:30 - Observations In My Community 11:50 - A Pharmacotherapy Solution 13:55 - Artificial Intelligence & Psychedelics 17:20 - Elon Musk's Neuralink 19:51 - The Ketamine Program 22:21 - Why Choose Ketamine? 23:35 - Skepticism In European Countries 26:01 - Daniel's Future Projects 28:35 - Outro About Daniel: Dr. Daniel Gehrlach is the associate director of biomarkers at HMNC Brain Health. After obtaining degrees in Pharmaceutical Biotechnology in Biberach and Medical Neurosciences at the Charité in Berlin, he completed his PhD at the Max Planck Institute of Neurobiology in Martinsried, Germany. He gained valuable experience in preclinical and translational in vivo models of affective disorders, in particular in the fields of anxiety, depression, and addiction. Daniel was awarded the Max Planck Institute's ‘Young Scientist Award 2019' for his doctoral project, which was also published in Nature Neuroscience. As associate director at HMNC Brain Health, he is the project lead for a Phase II clinical trial and leading the biomarker team. Connect with Daniel: Twitter: https://twitter.com/i/flow/login?redirect_after_login=%2Fdaniel_gehrlach LinkedIn: https://www.linkedin.com/in/dr-daniel-gehrlach?utm_source=share&utm_campaign=share_via&utm_content=profile&utm_medium=ios_app Thank you so much for joining us! Psychedelic Conversations Podcast is designed to educate, inform, and expand awareness. For more information, please head over to https://www.psychedelicconversations.com Please share with your friends or leave a review so that we can reach more people and feel free to join us in our private Facebook group to keep the conversation going. https://www.facebook.com/groups/psychedelicconversations This show is for information purposes only, and is not intended to provide mental health or medical advice. About Susan Guner: Susan is a trained somatic, trauma-informed holistic psychotherapist with a mindfulness-based approach grounded in Transpersonal Psychology that focuses on holistic perspective through introspection, insight, and empathetic self-exploration to increase self-awareness, allowing the integration of the mind, body and spirit aspects of human experience in personal growth and development. Connect with Susan: Website: https://www.psychedelicconversations.com/ Facebook: http://www.facebook.com/susan.guner LinkedIn: https://www.linkedin.com/in/susan-guner/ Instagram: http://www.instagram.com/susanguner Twitter: http://www.twitter.com/susanguner Blog: https://susanguner.medium.com/ Podcast: https://anchor.fm/susan-guner #PsychedelicScience2023 #SusanGuner #DanielGehrlach

In today's episode, we meet with Danny O'Malley a producer on Chef's Table, and Alex Rivest, an MIT-educated neuroscientist. Together they directed a riveting climate documentary disguised as an adventure epic that speaks to the heart versus the viewer's mind. CANARY is the film featuring Lonnie Thompson's climate odyssey atop the Quelccaya Ice Cap. Join us as we delve into the remarkable work and life of Dr. Lonnie Thompson, a pioneering glaciologist whose research has been instrumental in shedding light on the impacts of climate change. Dr. Thompson has spent decades studying glaciers and ice caps around the world, but his work on the Quelccaya Ice Cap is particularly significant. Located high in the Peruvian Andes, Quelccaya is one of the world's largest tropical ice caps. It serves as a critical indicator of climate change due to its sensitivity to temperature variations. Dr. Thompson's research involves drilling ice cores to extract ancient air bubbles, allowing scientists to analyze the Earth's past climate conditions with unparalleled precision. The documentary, "CANARY" takes us on a breathtaking journey to the top of the Quelccaya Ice Cap, where Lonnie, his team, and an entire film crew conduct and film the research. At an elevation of 18,000 feet, this desolate, icy expanse provides a stark visual representation of the profound changes our planet is undergoing. Through stunning visuals and interviews with the scientists, the film documents the dramatic retreat of Quelccaya's ice, which has accelerated in recent decades. At the peak of Dr. Thompson's career, he received some devastating health news that threatened to halt his progress. The directors draw a parallel between Lonnie's struggles to accept his health condition, and the broader challenge that many of us face in accepting the reality of climate change caused by a warming atmosphere.  Through their dedication and storytelling, Dr. Thompson, Rivest, and O'Malley inspire us all to take action to protect our world for future generations. Links: Find showings here: https://canary.oscilloscope.net/ Join us at Climate Week NYC here: https://www.climateweeknyc.org/events/canary-documentary-film-screening   Guest Bios (provided by the guest):  Danny O'Malley Danny O'Malley is a Grammy-nominated and James Beard-nominated film director, best known for his work on Netflix's Chef's Table, where he serves as co-executive producer and director. Danny has an extensive background in filming, collaborating with various bands across the U.S., including Tegan and Sara, The Rentals, The Decemberists, Kraftwerk, and more. Notably, his documentary ‘States', part of Tegan and Sara's release ‘Get Along' was nominated for a Grammy in the category of Best Long Form Music Video. Danny initially made his mark in documentary television as a story producer, and his work has been featured on major platforms such as Netflix, Fox Sports One, and NBC. On Chef's Table, Danny is a key driving force shaping the character-driven storytelling that defines the show's signature style. Danny, and his directing partner Alex Rivest PhD, won the Alfred P. Sloan development grant in 2017, which led to the creation of his first feature ‘Canary.'   Alex Rivest Alex Rivest is an MIT-trained PhD Neuroscientist. Having worked alongside Nobel Prize winner Dr. Susumu Tonegawa, Alex's research has been published in two of the most highly renowned scientific journals, Science and Nature Neuroscience. Alex grew up in an environment where curiosity and question-asking were highly valued, and he has dedicated his life to helping teach others about the wonders of the world. As an educator, he received the Angus MacDonald Award for Excellence in Undergraduate Teaching at MIT and founded the nonprofit Blue Kitabu, which built a sustainable primary school in central Ghana. As a science filmmaker, Alex's videos have accumulated over 70 million views online, and have been featured everywhere, from billboards in Times Square to installations in science museums, and even in an opera production of “Das Rheingold.” CANARY is his directorial debut.

Life Diversity Leads to a Happier Life (New Research Study) Research has recently discovered a correlation between our happiness and the amount of diversity we create in our lives.  When we enhance our mental and physical routines, our happiness state increases.  Additionally, these diverse activities affect our brain (the hippocampus and the striatum), supporting diversification's positive results. Aaron S. Heller, Tracey C. Shi, C. E. Chiemeka Ezie, Travis R. Reneau, Lara M. Baez, Conor J. Gibbons, Catherine A. Hartley. Association between real-world experiential diversity and positive affect relates to hippocampal–striatal functional connectivity. Nature Neuroscience, 2020; DOI: 10.1038/s41593-020-0636-4 New Happiness Podcast episode with Dr. Robert Puff, Newport Beach Psychologist

To access the full episode and our conference library of 200+ fascinating psychology talks and interviews (with certification), please visit: https://twumembers.com In this thought-provoking episode, Professor Lisa Feldman Barrett delves into the intricate workings of the brain, and its primary role in regulating bodily systems for overall well-being. Unravel the concept of affect, the ever-present feelings we experience, influencing our responses to life's challenges. Discover the transformative power of emotional granularity, as it enables us to discern and label emotions with precision, impacting our mental health profoundly. Gain insights into how investing in diverse experiences and learning can shape our future, "seeding" our brains for positive changes and empowering us to embrace personal responsibility. Uncover the path to enhanced resilience and a brighter life in this compelling talk. --- Dr Lisa Feldman Barrett is in the top one percent of the most cited scientists in the world for her revolutionary research in psychology and neuroscience. She is a Distinguished Professor of Psychology at Northeastern University, and also holds appointments at Harvard Medical School and Massachusetts General Hospital, where she is Chief Science Officer for the Center for Law, Brain & Behavior. In addition to the books Seven and a Half Lessons About the Brain and How Emotions are Made, Dr. Barrett has published over 260 peer-reviewed, scientific papers appearing in Science, Nature Neuroscience, and other top journals in psychology and cognitive neuroscience, as well as six academic volumes. She has also given a popular TED talk with over 6.5 million views. You can learn more about Dr Barrett's work by going to: www.lisafeldmanbarrett.com --- This session was recorded as part of the "Holistic Psychotherapy Summit" in January 2023. To access the full conference package, as well as supporting materials, quizzes, and certification, please visit: https://theweekenduniversity.com/membership. --- Interview Links: — Seven and a Half Lessons About the Brain - Lisa Feldman Barrett: https://amzn.to/3CWM1VQ — How Emotions are Made - Lisa Feldman Barrett: https://amzn.to/3Rx1BeT — Dr Barrett's website: www.lisafeldmanbarrett.com — Matter and Consciousness - Dr Iain McGilchrist: https://bit.ly/3RGSQz0 3 Books Dr Barrett Recommends Every Therapist Should Read: — Between us by Batja Mesquita - https://amzn.to/3FdYkxT — The End of Trauma by George Bonanno - https://amzn.to/3AW1fbL — How Emotions are Made by Lisa Feldman Barrett - https://amzn.to/3GVdxFl

To access the full episode and our conference library of 200+ fascinating psychology talks and interviews (with certification), please visit: https://twumembers.com In this episode I'm joined by Lisa Feldman Barrett to discuss the differences between the classical psychological view of emotions versus her work on the subject. Also discussed is how the brain uses past experiences in order to predict rather than react, and finally we discuss what it means to be experientially blind. --- Dr Lisa Feldman Barrett is in the top one percent of the most cited scientists in the world for her revolutionary research in psychology and neuroscience. She is a Distinguished Professor of Psychology at Northeastern University, and also holds appointments at Harvard Medical School and Massachusetts General Hospital, where she is Chief Science Officer for the Center for Law, Brain & Behavior. In addition to the books Seven and a Half Lessons About the Brain and How Emotions are Made, Dr. Barrett has published over 260 peer-reviewed, scientific papers appearing in Science, Nature Neuroscience, and other top journals in psychology and cognitive neuroscience, as well as six academic volumes. She has also given a popular TED talk with over 6.5 million views. You can learn more about Dr Barrett's work by going to: www.lisafeldmanbarrett.com --- This session was recorded as part of "Holistic Psychotherapy Summit" in January 2023. To access the full conference package, as well as supporting materials, quizzes, and certification, please visit: https://theweekenduniversity.com/membership --- Dr. Lisa Feldman Barrett is a psychologist, neuroscientist, professor, bestselling author, and one of the most cited scientists in the world. She received a National Institutes of Health Director's Pioneer Award for her revolutionary research on emotion in the brain. These highly competitive, multimillion-dollar awards are given to scientists of exceptional creativity who are expected to transform biomedical and behavioral research. She also received a Guggenheim Fellowship in 2019, the APS Mentor Award for Lifetime Achievement in 2018, and the APA Distinguished Scientific Contribution Award in Psychology in 2021. Among her many accomplishments, Dr. Barrett has testified before Congress, presented her research to the FBI, consulted with the National Cancer Institute, appeared on Through The Wormhole with Morgan Freeman and The Today Show with Maria Shriver, and been a featured guest on public television and podcast and radio programs worldwide. She is also an elected fellow of the American Academy of Arts & Sciences and the Royal Society of Canada. --- Interview Links: — Seven and a Half Lessons About the Brain - Lisa Feldman Barrett: https://amzn.to/3CWM1VQ — How Emotions are Made - Lisa Feldman Barrett: https://amzn.to/3Rx1BeT — Dr Barrett's website: www.lisafeldmanbarrett.com — Matter and Consciousness - Dr Iain McGilchrist: https://bit.ly/3RGSQz0 3 Books Dr Porges Recommends Every Therapist Should Read: — Between us by Batja Mesquita - https://amzn.to/3FdYkxT — The End of Trauma by George Bonanno - https://amzn.to/3AW1fbL — How Emotions are Made by Lisa Feldman Barrett - https://amzn.to/3GVdxFl

Chronic pain, according to a 2023 study, affects more Americans than diabetes, depression, and hypertension. Yet the disease is poorly understood, often undiagnosed or misdiagnosed, and effective treatments are in short supply.   A recent study in Nature Neuroscience provides new insights into how the disease affects the nervous system. For the first time, researchers recorded data from inside the brains of individuals who were suffering from chronic pain and found distinct biomarkers for the disease. These insights are an important first step toward better diagnosing and treating chronic pain.   In this episode, the lead author of that study, Prasad Shirvalkar, a neurologist and interventional pain medicine specialist at the University of California, San Francisco, talks with managing editor Jason Lloyd about his research and how it could transform physicians' understanding and treatment of what Shirvalkar calls a “multi-dimensional beast.”   Resources   ·     Read the article: Prasad Shirvalkar, Jordan Prosky, Gregory Chin, Parima Ahmadipour, Omid G. Sani, Maansi Desai, Ashlyn Schmitgen, Heather Dawes, Maryam M. Shanechi, Philip A. Starr, and Edward F. Chang, “First-in-human prediction of chronic pain state using intracranial neural biomarkers,” Nature Neuroscience 26 (2023): 1090–1099. ·     Prasad Shirvalkar leads the Shirvalkar Pain Neuromodulation Lab at the University of California San Francisco. ·     More about Shirvalkar's research in the New York Times: “Scientists Find Brain Signals of Chronic Pain.”   Transcript Coming soon!

Jonathan Jay Couey discusses his evolving COVID theory, why he no longer believes the now official "lab leak" narrative, and how the "no virus" people can get so many things right yet be so far off the mark, throwing the baby out with the bathwater. Much of what we know about coronaviruses is not done from wild-harvested coronaviruses but from sequences detected in the wild and then replicated in a DNA cloning technology form. This means that these coronaviruses rapidly lose fidelity or potency as they return to a natural viral quasispecies swarm where the majority of particles are replication incompetent. If enough coronavirus were released at best it would create an initial effect, but then dissipate. His theory is something more akin to COVID having been a low-yield bioweapon. The overarching idea is to convince young adults and their children to be genetically and biologically monitored for the rest of their lives. Elites want to use this information to achieve transhuman immortality. They can't depopulate us because they haven't collected the data that's here yet. Watch On BitChute / Brighteon / Rokfin / Rumble / YouTube Geopolitics & Empire · J.J. Couey: COVID as Low-Yield Bioweapon, Elites Want Genetic Info for Immortality #337 *Support Geopolitics & Empire! Become a Member https://geopoliticsandempire.substack.comDonate https://geopoliticsandempire.com/donationsConsult https://geopoliticsandempire.com/consultation **Visit Our Affiliates & Sponsors! Above Phone https://abovephone.com/?above=geopoliticseasyDNS (use code GEOPOLITICS for 15% off!) https://easydns.comEscape The Technocracy course (15% discount using link) https://escapethetechnocracy.com/geopoliticsPassVult https://passvult.comSociatates Civis (CitizenHR, CitizenIT, CitizenPL) https://societates-civis.comWise Wolf Gold https://www.wolfpack.gold/?ref=geopolitics Websites Gigaohm Biological https://gigaohmbiological.com DRASTIC Founder Renounces Lab Leak of COVID's Origins https://michaelpsenger.substack.com/p/drastic-founder-renounces-lab-leak Medical Doctors for Covid Ethics International: Gigaohm Biological Presents https://www.twitch.tv/videos/1660073740 About Jonathan Jay Couey JJC is a member of the research faculty of the University of Pittsburgh School of Medicine.  His research focuses on trying to connect structure to function using patch clamp and optogenetics. JJC has published work in Science, Nature Neuroscience, PNAS, and Neuron. *Podcast intro music is from the song "The Queens Jig" by "Musicke & Mirth" from their album "Music for Two Lyra Viols": http://musicke-mirth.de/en/recordings.html (available on iTunes or Amazon)

We're re-releasing one of our favorite episodes from the past year with Lisa Feldman Barrett.Dr. Lisa Feldman Barrett is among the top one percent most cited scientists in the world for her revolutionary research in psychology and neuroscience. She is a University Distinguished Professor of Psychology at Northeastern University. She also holds appointments at Harvard Medical School and Massachusetts General Hospital, where she is Chief Science Officer for the Center for Law, Brain & Behavior.Her books include Seven and a Half Lessons About the Brain and How Emotions are Made. She has published over 240 peer-reviewed, scientific papers appearing in Science, Nature Neuroscience, and other top journals. Dr. Barrett has been called “the most important affective scientist of our time”. In this episode, I talk to renowned neuroscientist Dr. Lisa Feldman Barrett about emotions and the brain. She reveals what the true function of the brain is⎯and it's not for thinking. We also discuss the impact of past experiences on our cognition and what we can do to overcome our own detrimental patterns. Further into our discussion, Dr. Lisa challenges the traditionally held view that emotions are universal. In her own theory of constructed emotion, she argues that variability in emotional expression exists due to socialization and language differences. We also touch on the topics of hallucinogens, culture, education, relationships, and authoritarianism. Website: lisafeldmanbarrett.comTwitter: @LFeldmanBarrett Topics00:01:42 Lisa's interest in clinical psychology00:03:53 A biological approach to emotions00:06:29 Why do we have a neocortex? 00:14:49 The default mode network00:21:47 The brain is not for thinking00:25:06 Authoritarianism during economic hardship00:32:04 Psychological entropy00:35:33 The brain weather forecast00:44:16 The mind-brain problem00:47:37 Relationships are reflexive00:51:46 Emotional expression isn't universal00:58:35 Why you shouldn't trust psychology textbooks / 6 universal emotions?01:03:03 Reaching out to Paul Ekman 01:10:42 The theory of constructed emotion01:16:49 The role of socialization and language in emotions 01:23:43 The never-ending domain-general vs domain-specific debate in cognitive science